-
1
-
-
0017265531
-
Long-term methamphetamine induced changes in brain catecholamines in tolerant rhesus monkeys
-
&
-
Seiden, L.S., M.W. Fischman & C.R. Schuster. 1976. Long-term methamphetamine induced changes in brain catecholamines in tolerant rhesus monkeys. Drug Alcohol Depend. 1 : 215 219.
-
(1976)
Drug Alcohol Depend.
, vol.1
, pp. 215-219
-
-
Seiden, L.S.1
Fischman, M.W.2
Schuster, C.R.3
-
2
-
-
0018937896
-
Blockade of methamphetamine-induced depression of tyrosine hydroxylase by GABA transaminase inhibitors
-
&
-
Hotchkiss, A. & J.W. Gibb. 1980. Blockade of methamphetamine-induced depression of tyrosine hydroxylase by GABA transaminase inhibitors. Eur. J. Pharmacol. 66 : 201 205.
-
(1980)
Eur. J. Pharmacol.
, vol.66
, pp. 201-205
-
-
Hotchkiss, A.1
Gibb, J.W.2
-
3
-
-
0020084295
-
Dopamine nerve terminal degeneration produced by high doses of methylamphetamine in the rat brain
-
Ricaurte, G.A., R.W. Guillery, L.S. Seiden, et al. 1982. Dopamine nerve terminal degeneration produced by high doses of methylamphetamine in the rat brain. Brain Res. 235 : 93 103.
-
(1982)
Brain Res.
, vol.235
, pp. 93-103
-
-
Ricaurte, G.A.1
Guillery, R.W.2
Seiden, L.S.3
-
4
-
-
0022272191
-
Methamphetamine: Toxicity to dopaminergic neurons
-
Seiden, L.S. 1985. Methamphetamine: toxicity to dopaminergic neurons. NIDA Res. Monogr. 62 : 100 116.
-
(1985)
NIDA Res. Monogr.
, vol.62
, pp. 100-116
-
-
Seiden, L.S.1
-
5
-
-
15844384993
-
Striatal dopamine nerve terminal markers in human, chronic methamphetamine users
-
Wilson, J.M., K.S. Kalasinsky, A.I. Levey, et al. 1996. Striatal dopamine nerve terminal markers in human, chronic methamphetamine users. Nat. Med. 2 : 699 703.
-
(1996)
Nat. Med.
, vol.2
, pp. 699-703
-
-
Wilson, J.M.1
Kalasinsky, K.S.2
Levey, A.I.3
-
6
-
-
9144271094
-
Methamphetamine produces neuronal inclusions in the nigrostriatal system and in PC12 cells
-
Fornai, F., P. Lenzi, M. Gesi, et al. 2004. Methamphetamine produces neuronal inclusions in the nigrostriatal system and in PC12 cells. J. Neurochem. 88 : 114 123.
-
(2004)
J. Neurochem.
, vol.88
, pp. 114-123
-
-
Fornai, F.1
Lenzi, P.2
Gesi, M.3
-
7
-
-
20144389039
-
Occurrence of neuronal inclusions combined with increased nigral expression of alpha-synuclein within dopaminergic neurons following treatment with amphetamine derivatives in mice
-
Fornai, F., P. Lenzi, M. Ferrucci, et al. 2005. Occurrence of neuronal inclusions combined with increased nigral expression of alpha-synuclein within dopaminergic neurons following treatment with amphetamine derivatives in mice. Brain Res. Bull. 65 : 405 413.
-
(2005)
Brain Res. Bull.
, vol.65
, pp. 405-413
-
-
Fornai, F.1
Lenzi, P.2
Ferrucci, M.3
-
8
-
-
0034791072
-
Parallel increases in lipid and protein oxidative markers in several mouse brain regions after methamphetamine treatment
-
Gluck, M.R., L.Y. Moy, E. Jayatilleke, et al. 2001. Parallel increases in lipid and protein oxidative markers in several mouse brain regions after methamphetamine treatment. J. Neurochem. 79 : 152 160.
-
(2001)
J. Neurochem.
, vol.79
, pp. 152-160
-
-
Gluck, M.R.1
Moy, L.Y.2
Jayatilleke, E.3
-
9
-
-
0034939055
-
Methamphetamine-induced dopaminergic neurotoxicity: Role of peroxynitrite and neuroprotective role of antioxidants and peroxynitrite decomposition catalysts
-
Imam, S.Z., J. el-Yazal, G.D. Newport, et al. 2001. Methamphetamine- induced dopaminergic neurotoxicity: role of peroxynitrite and neuroprotective role of antioxidants and peroxynitrite decomposition catalysts. Ann. N. Y. Acad. Sci. 939 : 366 380.
-
(2001)
Ann. N. Y. Acad. Sci.
, vol.939
, pp. 366-380
-
-
Imam, S.Z.1
El-Yazal, J.2
Newport, G.D.3
-
10
-
-
34248192413
-
Mechanisms involved in the formation of dopamine-induced intracellular bodies within striatal neurons
-
Lazzeri, G., P. Lenzi, C.L. Busceti, et al. 2007. Mechanisms involved in the formation of dopamine-induced intracellular bodies within striatal neurons. J. Neurochem. 101 : 1414 1427.
-
(2007)
J. Neurochem.
, vol.101
, pp. 1414-1427
-
-
Lazzeri, G.1
Lenzi, P.2
Busceti, C.L.3
-
11
-
-
0028329215
-
Methamphetamine neurotoxicity involves vacuolation of endocytic organelles and dopamine-dependent intracellular oxidative stress
-
Cubells, J.F., S. Rayport, G. Rajendran, et al. 1994. Methamphetamine neurotoxicity involves vacuolation of endocytic organelles and dopamine-dependent intracellular oxidative stress. J. Neurosci. 14 : 2260 2271.
-
(1994)
J. Neurosci.
, vol.14
, pp. 2260-2271
-
-
Cubells, J.F.1
Rayport, S.2
Rajendran, G.3
-
12
-
-
0037109770
-
Methamphetamine-induced degeneration of dopaminergic neurons involves autophagy and upregulation of dopamine synthesis
-
Larsen, K.E., E.A. Fon, T.G. Hastings, et al. 2002. Methamphetamine- induced degeneration of dopaminergic neurons involves autophagy and upregulation of dopamine synthesis. J. Neurosci. 22 : 8951 8960.
-
(2002)
J. Neurosci.
, vol.22
, pp. 8951-8960
-
-
Larsen, K.E.1
Fon, E.A.2
Hastings, T.G.3
-
13
-
-
17444373101
-
Ubiquitin-immunoreactive structures in the midbrain of methamphetamine abusers
-
Quan, L., T. Ishikawa, T. Michiue, et al. 2005. Ubiquitin-immunoreactive structures in the midbrain of methamphetamine abusers. Leg. Med. (Tokyo) 7 : 144 150.
-
(2005)
Leg. Med. (Tokyo)
, vol.7
, pp. 144-150
-
-
Quan, L.1
Ishikawa, T.2
Michiue, T.3
-
14
-
-
0033884355
-
The role of the locus coeruleus in the development of Parkinson's disease
-
Gesi, M., P. Soldani, F.S. Giorgi, et al. 2000. The role of the locus coeruleus in the development of Parkinson's disease. Neurosci. Biobehav. Rev. 24 : 655 668.
-
(2000)
Neurosci. Biobehav. Rev.
, vol.24
, pp. 655-668
-
-
Gesi, M.1
Soldani, P.2
Giorgi, F.S.3
-
15
-
-
35448979969
-
Noradrenaline in Parkinson's disease: From disease progression to current therapeutics
-
Fornai, F., A.B. di Poggio, A. Pellegrini, et al. 2007. Noradrenaline in Parkinson's disease: from disease progression to current therapeutics. Curr. Med. Chem. 14 : 2330 2334.
-
(2007)
Curr. Med. Chem.
, vol.14
, pp. 2330-2334
-
-
Fornai, F.1
Di Poggio, A.B.2
Pellegrini, A.3
-
16
-
-
34250025128
-
Norepinephrine: The redheaded stepchild of Parkinson's disease
-
&
-
Rommelfanger, K.S. & D. Weinshenker. 2007. Norepinephrine: the redheaded stepchild of Parkinson's disease. Biochem. Pharmacol. 74 : 177 190.
-
(2007)
Biochem. Pharmacol.
, vol.74
, pp. 177-190
-
-
Rommelfanger, K.S.1
Weinshenker, D.2
-
17
-
-
0035693854
-
Is methamphetamine abuse a risk factor in parkinsonism?
-
Guilarte, T.R. 2001. Is methamphetamine abuse a risk factor in parkinsonism? Neurotoxicology. 22 : 725 731.
-
(2001)
Neurotoxicology.
, vol.22
, pp. 725-731
-
-
Guilarte, T.R.1
-
19
-
-
0027972286
-
Attenuation of methamphetamine-induced neurotoxicity in copper/zinc superoxide dismutase transgenic mice
-
Cadet, J.L., P. Sheng, S. Ali, et al. 1994. Attenuation of methamphetamine-induced neurotoxicity in copper/zinc superoxide dismutase transgenic mice. J. Neurochem. 62 : 380 383.
-
(1994)
J. Neurochem.
, vol.62
, pp. 380-383
-
-
Cadet, J.L.1
Sheng, P.2
Ali, S.3
-
20
-
-
0029348218
-
Neurotoxicity, drugs and abuse, and the CuZn-superoxide dismutase transgenic mice
-
Cadet, J.L., S.F. Ali, R.B. Rothman, et al. 1995. Neurotoxicity, drugs and abuse, and the CuZn-superoxide dismutase transgenic mice. Mol. Neurobiol. 11 : 155 163.
-
(1995)
Mol. Neurobiol.
, vol.11
, pp. 155-163
-
-
Cadet, J.L.1
Ali, S.F.2
Rothman, R.B.3
-
21
-
-
0035155763
-
Peroxynitrite plays a role in methamphetamine-induced dopaminergic neurotoxicity: Evidence from mice lacking neuronal nitric oxide synthase gene or overexpressing copper-zinc superoxide dismutase
-
Imam, S.Z., G.D. Newport, Y. Itzhak, et al. 2001. Peroxynitrite plays a role in methamphetamine-induced dopaminergic neurotoxicity: evidence from mice lacking neuronal nitric oxide synthase gene or overexpressing copper-zinc superoxide dismutase. J. Neurochem. 76 : 745 749.
-
(2001)
J. Neurochem.
, vol.76
, pp. 745-749
-
-
Imam, S.Z.1
Newport, G.D.2
Itzhak, Y.3
-
22
-
-
0027401203
-
Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis
-
Rosen, D.R., T. Siddique, D. Patterson, et al. 1993. Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis. Nature 362 : 59 62.
-
(1993)
Nature
, vol.362
, pp. 59-62
-
-
Rosen, D.R.1
Siddique, T.2
Patterson, D.3
-
23
-
-
0035516124
-
From Charcot to Lou Gehrig: Deciphering selective motor neuron death in ALS
-
&
-
Cleveland, D.W. & J.D. Rothstein. 2001. From Charcot to Lou Gehrig: deciphering selective motor neuron death in ALS. Nat. Rev. Neurosci. 2 : 806 819.
-
(2001)
Nat. Rev. Neurosci.
, vol.2
, pp. 806-819
-
-
Cleveland, D.W.1
Rothstein, J.D.2
-
24
-
-
0031724091
-
Diagnosis of amyotrophic lateral sclerosis
-
Rowland, L.P. 1998. Diagnosis of amyotrophic lateral sclerosis. J. Neurol. Sci. 160 (Suppl. 1 S6 S24.
-
(1998)
J. Neurol. Sci.
, vol.160
, Issue.1
-
-
Rowland, L.P.1
-
25
-
-
34447506680
-
Transgenic mice with human mutant genes causing Parkinson's disease and amyotrophic lateral sclerosis provide common insight into mechanisms of motor neuron selective vulnerability to degeneration
-
Martin, L.J. 2007. Transgenic mice with human mutant genes causing Parkinson's disease and amyotrophic lateral sclerosis provide common insight into mechanisms of motor neuron selective vulnerability to degeneration. Rev. Neurosci. 18 : 115 136.
-
(2007)
Rev. Neurosci.
, vol.18
, pp. 115-136
-
-
Martin, L.J.1
-
26
-
-
34248202138
-
Focality of upper and lower motor neuron degeneration at the clinical onset of ALS
-
&
-
Ravits, J., P. Paul & C. Jorg. 2007. Focality of upper and lower motor neuron degeneration at the clinical onset of ALS. Neurology 68 : 1571 1575.
-
(2007)
Neurology
, vol.68
, pp. 1571-1575
-
-
Ravits, J.1
Paul, P.2
Jorg, C.3
-
27
-
-
0028284779
-
Motor neuron degeneration in mice that express a human Cu/Zn superoxide dismutase mutation
-
Gurney, M.E., H. Pu, A.Y. Chiu, et al. 1994. Motor neuron degeneration in mice that express a human Cu/Zn superoxide dismutase mutation. Science. 264 : 1772 1775.
-
(1994)
Science.
, vol.264
, pp. 1772-1775
-
-
Gurney, M.E.1
Pu, H.2
Chiu, A.Y.3
-
28
-
-
33845361630
-
Motor neuron degeneration in amyotrophic lateral sclerosis mutant superoxide dismutase-1 transgenic mice: Mechanisms of mitochondriopathy and cell death
-
Martin, L.J., Z. Liu, K. Chen, et al. 2007. Motor neuron degeneration in amyotrophic lateral sclerosis mutant superoxide dismutase-1 transgenic mice: mechanisms of mitochondriopathy and cell death. J. Comp. Neurol. 500 : 20 46.
-
(2007)
J. Comp. Neurol.
, vol.500
, pp. 20-46
-
-
Martin, L.J.1
Liu, Z.2
Chen, K.3
-
29
-
-
0027946294
-
Development of central nervous system pathology in a murine transgenic model of human amyotrophic lateral sclerosis
-
&
-
Dal Canto, M.C. & M.E. Gurney. 1994. Development of central nervous system pathology in a murine transgenic model of human amyotrophic lateral sclerosis. Am. J. Pathol. 145 : 1271 1279.
-
(1994)
Am. J. Pathol.
, vol.145
, pp. 1271-1279
-
-
Dal Canto, M.C.1
Gurney, M.E.2
-
30
-
-
0032079517
-
Massive mitochondrial degeneration in motor neurons triggers the onset of amyotrophic lateral sclerosis in mice expressing a mutant SOD1
-
&
-
Kong, J. & Z. Xu. 1998. Massive mitochondrial degeneration in motor neurons triggers the onset of amyotrophic lateral sclerosis in mice expressing a mutant SOD1. J. Neurosci. 18 : 3241 3250.
-
(1998)
J. Neurosci.
, vol.18
, pp. 3241-3250
-
-
Kong, J.1
Xu, Z.2
-
31
-
-
0032544674
-
Aggregation and motor neuron toxicity of an ALS-linked SOD1 mutant independent from wild-type SOD1
-
Bruijn, L.I., M.K. Houseweart, S. Kato, et al. 1998. Aggregation and motor neuron toxicity of an ALS-linked SOD1 mutant independent from wild-type SOD1. Science 281 : 1851 1854.
-
(1998)
Science
, vol.281
, pp. 1851-1854
-
-
Bruijn, L.I.1
Houseweart, M.K.2
Kato, S.3
-
32
-
-
3242736666
-
Amyotrophic lateral sclerosis with neuronal intranuclear protein inclusions
-
Seilhean, D., J. Takahashi, K.H. El Hachimi, et al. 2004. Amyotrophic lateral sclerosis with neuronal intranuclear protein inclusions. Acta Neuropathol. 108 : 81 87.
-
(2004)
Acta Neuropathol.
, vol.108
, pp. 81-87
-
-
Seilhean, D.1
Takahashi, J.2
El Hachimi, K.H.3
-
33
-
-
33644831056
-
"forme fruste" of amyotrophic lateral sclerosis with dementia: A report of five autopsy cases without dementia and with ubiquitinated intraneuranal inclusions
-
&
-
Ota, S., K. Tsuchiya & H. Akiyama. 2005. "Forme fruste" of amyotrophic lateral sclerosis with dementia: a report of five autopsy cases without dementia and with ubiquitinated intraneuranal inclusions. Neuropathology 25 : 326 335.
-
(2005)
Neuropathology
, vol.25
, pp. 326-335
-
-
Ota, S.1
Tsuchiya, K.2
Akiyama, H.3
-
34
-
-
33749668139
-
Amyotrophic lateral sclerosis with dementia: An autopsy case showing many Bunina bodies, tau-positive neuronal and astrocytic plaque-like pathologies, and pallido-nigral degeneration
-
Yokota, O., K. Tsuchiya, T. Oda, et al. 2006. Amyotrophic lateral sclerosis with dementia: an autopsy case showing many Bunina bodies, tau-positive neuronal and astrocytic plaque-like pathologies, and pallido-nigral degeneration. Acta Neuropathol. 112 : 633 645.
-
(2006)
Acta Neuropathol.
, vol.112
, pp. 633-645
-
-
Yokota, O.1
Tsuchiya, K.2
Oda, T.3
-
35
-
-
34447308523
-
A familial form of pallidoluysionigral degeneration and amyotrophic lateral sclerosis with divergent clinical presentations
-
Portera-Cailliau, C., C. Russ, R.H. Jr. Brown, et al. 2007. A familial form of pallidoluysionigral degeneration and amyotrophic lateral sclerosis with divergent clinical presentations. J. Neuropathol. Exp. Neurol. 66 : 650 659.
-
(2007)
J. Neuropathol. Exp. Neurol.
, vol.66
, pp. 650-659
-
-
Portera-Cailliau, C.1
Russ, C.2
Brown Jr., R.H.3
-
36
-
-
34249048839
-
Amyotrophic lateral sclerosis with dementia showing clinical parkinsonism and severe degeneration of the substantia nigra: Report of an autopsy case
-
&
-
Shintaku, M., K. Oyanagi & D. Kaneda. 2007. Amyotrophic lateral sclerosis with dementia showing clinical parkinsonism and severe degeneration of the substantia nigra: report of an autopsy case. Neuropathology 27 : 295 299.
-
(2007)
Neuropathology
, vol.27
, pp. 295-299
-
-
Shintaku, M.1
Oyanagi, K.2
Kaneda, D.3
-
37
-
-
0018881202
-
Long-lasting depletions of striatal dopamine and loss of dopamine uptake sites following repeated administration of methamphetamine
-
Wagner, G.C., G.A. Ricaurte, L.S. Seiden, et al. 1980. Long-lasting depletions of striatal dopamine and loss of dopamine uptake sites following repeated administration of methamphetamine. Brain Res. 181 : 151 160.
-
(1980)
Brain Res.
, vol.181
, pp. 151-160
-
-
Wagner, G.C.1
Ricaurte, G.A.2
Seiden, L.S.3
-
38
-
-
4644304559
-
Methamphetamine and MDMA (ecstasy) neurotoxicity: "of mice and men"
-
&
-
Itzhak, J. & C. Achat-Mendes. 2004. Methamphetamine and MDMA (ecstasy) neurotoxicity: "of mice and men". IUBMB Life. 56 : 249 255.
-
(2004)
IUBMB Life.
, vol.56
, pp. 249-255
-
-
Itzhak, J.1
Achat-Mendes, C.2
-
39
-
-
33745651192
-
Mechanisms of methamphetamine-induced dopaminergic neurotoxicity
-
&
-
Riddle, E.L., A.E. Fleckenstein & G.R. Hanson. 2006. Mechanisms of methamphetamine-induced dopaminergic neurotoxicity. AAPS J. 8 : 413 418.
-
(2006)
AAPS J.
, vol.8
, pp. 413-418
-
-
Riddle, E.L.1
Fleckenstein, A.E.2
Hanson, G.R.3
-
40
-
-
20444498341
-
Recognition and management of complications of new recreational drug use
-
&
-
Ricaurte, G.A. & U.D. McCann. 2005. Recognition and management of complications of new recreational drug use. Lancet 365 : 2137 2145.
-
(2005)
Lancet
, vol.365
, pp. 2137-2145
-
-
Ricaurte, G.A.1
McCann, U.D.2
-
41
-
-
0027426169
-
Amyotrophic lateral sclerosis and structural defects in Cu, Zn superoxide dismutase
-
Deng, H.-X., A. Hentati, J.A. Tainer, et al. 1993. Amyotrophic lateral sclerosis and structural defects in Cu, Zn superoxide dismutase. Science 261 : 1047 1051.
-
(1993)
Science
, vol.261
, pp. 1047-1051
-
-
Deng, H.-X.1
Hentati, A.2
Tainer, J.A.3
-
42
-
-
33750363298
-
The roles of intracellular protein-degradation pathways in neurodegeneration
-
Rubinsztein, D.C. 2006. The roles of intracellular protein-degradation pathways in neurodegeneration. Nature 443 : 780 786.
-
(2006)
Nature
, vol.443
, pp. 780-786
-
-
Rubinsztein, D.C.1
-
43
-
-
34247464677
-
The parkinsonian neurotoxin rotenone activates calpain and caspase-3 leading to motoneuron degeneration in spinal cord of Lewis rats
-
Samantaray, S., V.H. Knaryan, M.K. Guyton, et al. 2007. The parkinsonian neurotoxin rotenone activates calpain and caspase-3 leading to motoneuron degeneration in spinal cord of Lewis rats. Neuroscience 146 : 741 755.
-
(2007)
Neuroscience
, vol.146
, pp. 741-755
-
-
Samantaray, S.1
Knaryan, V.H.2
Guyton, M.K.3
-
44
-
-
0033711406
-
Calpain up-regulation in spinal cord of mice with 1-methyl-4 phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced Parkinson's disease
-
Ray, S.K., G.G. Wilford, S.F. Ali, et al. 2000. Calpain up-regulation in spinal cord of mice with 1-methyl-4 phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced Parkinson's disease. Ann. N.Y. Acad. Sci. 914 : 275 283.
-
(2000)
Ann. N.Y. Acad. Sci.
, vol.914
, pp. 275-283
-
-
Ray, S.K.1
Wilford, G.G.2
Ali, S.F.3
-
45
-
-
0036291490
-
Calpain up-regulation and neuron death in spinal cord of MPTP-induced parkinsonism in mice
-
Chera, B., K.E. Schaecher, A. Rocchini, et al. 2002. Calpain up-regulation and neuron death in spinal cord of MPTP-induced parkinsonism in mice. Ann. N.Y. Acad. Sci. 965 : 274 280.
-
(2002)
Ann. N.Y. Acad. Sci.
, vol.965
, pp. 274-280
-
-
Chera, B.1
Schaecher, K.E.2
Rocchini, A.3
-
46
-
-
1642395294
-
Immunofluorescent labelling of increased calpain expression and neuronal death in the spinal cord of 1-methyl-4 phenyl-1,2,3,6-tetrahydropyridine-treated mice
-
Chera, B., K.E. Schaecher, A. Rocchini, et al. 2004. Immunofluorescent labelling of increased calpain expression and neuronal death in the spinal cord of 1-methyl-4 phenyl-1,2,3,6-tetrahydropyridine-treated mice. Brain Res. 1006 : 150 156.
-
(2004)
Brain Res.
, vol.1006
, pp. 150-156
-
-
Chera, B.1
Schaecher, K.E.2
Rocchini, A.3
-
47
-
-
0034681471
-
Dopaminergic loss and inclusions body formation in alpha-synuclein mice: Implications for neurodegenerative disorders
-
Masliah, E., E. Rockenstein, I. Weinbergs, et al. 2000. Dopaminergic loss and inclusions body formation in alpha-synuclein mice: implications for neurodegenerative disorders. Science 287 : 1265 1269.
-
(2000)
Science
, vol.287
, pp. 1265-1269
-
-
Masliah, E.1
Rockenstein, E.2
Weinbergs, I.3
-
48
-
-
0034663176
-
Neuropathology in mice expressing human alpha-synuclein
-
Van Der Putten, H., K.-H. Wiederhold, A. Probst, et al. 2000. Neuropathology in mice expressing human alpha-synuclein. J. Neurosci. 20 : 6021 6029.
-
(2000)
J. Neurosci.
, vol.20
, pp. 6021-6029
-
-
Van Der Putten, H.1
Wiederhold, K.-H.2
Probst, A.3
-
49
-
-
30644471051
-
Parkinson's disease alpha-synuclein transgenic mice develop neuronal mitochondrial degeneration and cell death
-
Martin, L.J., Y. Pan, A.C. Price, et al. 2006. Parkinson's disease alpha-synuclein transgenic mice develop neuronal mitochondrial degeneration and cell death. J. Neurosci. 26 : 41 50.
-
(2006)
J. Neurosci.
, vol.26
, pp. 41-50
-
-
Martin, L.J.1
Pan, Y.2
Price, A.C.3
-
50
-
-
33750089740
-
Degradation of amyotrophic lateral sclerosis-linked mutant Cu,Zn-superoxide dismutase proteins by macroautophagy and the proteasome
-
&
-
Kabuta T., Y. Suzuki & K. Wada. 2006. Degradation of amyotrophic lateral sclerosis-linked mutant Cu,Zn-superoxide dismutase proteins by macroautophagy and the proteasome. J. Biol. Chem. 281 : 30524 30533.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 30524-30533
-
-
Kabuta, T.1
Suzuki, Y.2
Wada, K.3
-
51
-
-
3042723794
-
Autophagy: Molecular mechanisms, physiological functions and relevance in human pathology
-
&
-
Mariño, G. & C. López-Otín. 2004. Autophagy: molecular mechanisms, physiological functions and relevance in human pathology. Cell. Mol. Life Sci. 61 : 1439 1454.
-
(2004)
Cell. Mol. Life Sci.
, vol.61
, pp. 1439-1454
-
-
Mariño, G.1
López-Otín, C.2
-
52
-
-
0034785509
-
The gene encoding alsin, a protein with three guanine-nucleotide exchange factor domains, is mutated in a form of recessive amyotrophic lateral sclerosis
-
Yang, Y., A. Hentati, H.X. Deng, et al. 2001. The gene encoding alsin, a protein with three guanine-nucleotide exchange factor domains, is mutated in a form of recessive amyotrophic lateral sclerosis. Nat. Genet. 29 : 160 165.
-
(2001)
Nat. Genet.
, vol.29
, pp. 160-165
-
-
Yang, Y.1
Hentati, A.2
Deng, H.X.3
-
53
-
-
0034785483
-
A gene encoding a putative GTPase regulator is mutated in familial amyotrophic lateral sclerosis 2
-
Hadano, S., C.K. Hand, H. Osuga, et al. 2001. A gene encoding a putative GTPase regulator is mutated in familial amyotrophic lateral sclerosis 2. Nat. Genet. 29 : 166 173.
-
(2001)
Nat. Genet.
, vol.29
, pp. 166-173
-
-
Hadano, S.1
Hand, C.K.2
Osuga, H.3
-
54
-
-
6344257200
-
A mutation in the vesicle-trafficking protein VAPB causes late-onset spinal muscular atrophy and amyotrophic lateral sclerosis
-
Nishimura, A.L., M. Mitne-Neto, H.C. Silva, et al. 2004. A mutation in the vesicle-trafficking protein VAPB causes late-onset spinal muscular atrophy and amyotrophic lateral sclerosis. Am. J. Hum. Genet. 75 : 822 831.
-
(2004)
Am. J. Hum. Genet.
, vol.75
, pp. 822-831
-
-
Nishimura, A.L.1
Mitne-Neto, M.2
Silva, H.C.3
-
55
-
-
0037382240
-
Mutant dynactin in motor neuron disease
-
Puls, I., C. Jonnakuty, B.H. LaMonte, et al. 2003. Mutant dynactin in motor neuron disease. Nat. Genet. 33 : 455 456.
-
(2003)
Nat. Genet.
, vol.33
, pp. 455-456
-
-
Puls, I.1
Jonnakuty, C.2
Lamonte, B.H.3
-
56
-
-
0031959591
-
Linkage of the gene for an autosomal dominant form of juvenile amyotrophic lateral sclerosis to chromosome 9q34
-
Chance, P.F., B.A. Rabin, S.G. Ryan, et al. 1998. Linkage of the gene for an autosomal dominant form of juvenile amyotrophic lateral sclerosis to chromosome 9q34. Am. J. Hum. Genet. 62 : 633 640.
-
(1998)
Am. J. Hum. Genet.
, vol.62
, pp. 633-640
-
-
Chance, P.F.1
Rabin, B.A.2
Ryan, S.G.3
-
57
-
-
2442658908
-
DNA/RNA helicase gene mutations in a form of juvenile amyotrophic lateral sclerosis (ALS4)
-
Chen, Y.Z., C.L. Bennett, H.M. Huynh, et al. 2004. DNA/RNA helicase gene mutations in a form of juvenile amyotrophic lateral sclerosis (ALS4). Am. J. Hum. Genet. 74 : 1128 1135.
-
(2004)
Am. J. Hum. Genet.
, vol.74
, pp. 1128-1135
-
-
Chen, Y.Z.1
Bennett, C.L.2
Huynh, H.M.3
-
58
-
-
33645422711
-
ANG mutations segregate with familial and "sporadic" amyotrophic lateral sclerosis
-
Greenway, M.J., P.M. Andersen, C. Russ, et al. 2006. ANG mutations segregate with familial and "sporadic" amyotrophic lateral sclerosis. Nat. Genet. 38 : 411 413.
-
(2006)
Nat. Genet.
, vol.38
, pp. 411-413
-
-
Greenway, M.J.1
Andersen, P.M.2
Russ, C.3
-
59
-
-
0041308082
-
ALS2, a novel guanine nucleotide exchange factor for the small GTPase Rab5, is implicated in endosomal dynamics
-
Otomo, A., S. Hadano, T. Okada, et al. 2003. ALS2, a novel guanine nucleotide exchange factor for the small GTPase Rab5, is implicated in endosomal dynamics. Hum. Mol. Genet. 12 : 1671 1687.
-
(2003)
Hum. Mol. Genet.
, vol.12
, pp. 1671-1687
-
-
Otomo, A.1
Hadano, S.2
Okada, T.3
-
60
-
-
2642536202
-
Alsin is a Rab5 and Rac1 guanine nucleotide exchange factor
-
Topp, J.D., N.W. Gray, R.D. Gerard, et al. 2004. Alsin is a Rab5 and Rac1 guanine nucleotide exchange factor. J. Biol. Chem. 279 : 24612 24623.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 24612-24623
-
-
Topp, J.D.1
Gray, N.W.2
Gerard, R.D.3
-
62
-
-
34547640096
-
Common molecular signature in SOD1 for both sporadic and familial amyotrophic lateral sclerosis
-
Gruzman, A., W.L. Wood, E. Alpert, et al. 2007. Common molecular signature in SOD1 for both sporadic and familial amyotrophic lateral sclerosis. PNAS 104 : 12524 12529.
-
(2007)
PNAS
, vol.104
, pp. 12524-12529
-
-
Gruzman, A.1
Wood, W.L.2
Alpert, E.3
-
63
-
-
0031915174
-
Cytochrome c oxidase subunit I microdeletion in a patient with motor neuron disease
-
Comi, G.P., A. Bordoni, S. Salani, et al. 1998. Cytochrome c oxidase subunit I microdeletion in a patient with motor neuron disease. Ann. Neurol. 43 : 110 116.
-
(1998)
Ann. Neurol.
, vol.43
, pp. 110-116
-
-
Comi, G.P.1
Bordoni, A.2
Salani, S.3
-
64
-
-
33644832850
-
Motor neuron disease in a patient with a mitochondrial tRNAIle mutation
-
Borthwick, G.M., R.W. Taylor, T.J. Walls, et al. 2006. Motor neuron disease in a patient with a mitochondrial tRNAIle mutation. Ann. Neurol. 59 : 570 574.
-
(2006)
Ann. Neurol.
, vol.59
, pp. 570-574
-
-
Borthwick, G.M.1
Taylor, R.W.2
Walls, T.J.3
-
65
-
-
22844436451
-
Dynein mutations impair autophagic clearance of aggregate-prone proteins
-
Ravikumar, B., A. Acevedo-Arozena, S. Imarisio, et al. 2005. Dynein mutations impair autophagic clearance of aggregate-prone proteins. Nat. Genet. 37 : 771 776.
-
(2005)
Nat. Genet.
, vol.37
, pp. 771-776
-
-
Ravikumar, B.1
Acevedo-Arozena, A.2
Imarisio, S.3
-
66
-
-
33644551565
-
A motor neuron disease-associated mutation in p150Glued perturbs dynactin function and induces protein aggregation
-
Levy, J.R., C.J. Sumner, J.P. Caviston, et al. 2006. A motor neuron disease-associated mutation in p150Glued perturbs dynactin function and induces protein aggregation. J. Cell. Biol. 172 : 733 745.
-
(2006)
J. Cell. Biol.
, vol.172
, pp. 733-745
-
-
Levy, J.R.1
Sumner, C.J.2
Caviston, J.P.3
-
68
-
-
0036566266
-
Aggregate-prone proteins with polyglutamine and polyalanine expansions are degraded by autophagy
-
&
-
Ravikumar, B., R. Duden & D.C. Rubinsztein. 2002. Aggregate-prone proteins with polyglutamine and polyalanine expansions are degraded by autophagy. Hum. Mol. Genet. 11 : 1107 1117.
-
(2002)
Hum. Mol. Genet.
, vol.11
, pp. 1107-1117
-
-
Ravikumar, B.1
Duden, R.2
Rubinsztein, D.C.3
-
69
-
-
8844220536
-
Huntingtin and the molecular pathogenesis of Huntington's disease (Fourth in molecular medicine review series)
-
&
-
Landles, C. & G.P. Bates. 2004. Huntingtin and the molecular pathogenesis of Huntington's disease (Fourth in molecular medicine review series). EMBO Rep. 5 : 958 963.
-
(2004)
EMBO Rep.
, vol.5
, pp. 958-963
-
-
Landles, C.1
Bates, G.P.2
-
70
-
-
0034307476
-
Huntingtin expression stimulates endosomal-lysosomal activity, endosome tubulation, and autophagy
-
Kegel, K.B., M. Kim, E. Sapp, et al. 2000. Huntingtin expression stimulates endosomal-lysosomal activity, endosome tubulation, and autophagy. J. Neurosci. 20 : 7268 7278.
-
(2000)
J. Neurosci.
, vol.20
, pp. 7268-7278
-
-
Kegel, K.B.1
Kim, M.2
Sapp, E.3
-
71
-
-
34250183177
-
HDAC6 rescues neurodegeneration and provides an essential link between autophagy and the UPS
-
Pandey, U.B., Z. Nie, Y. Batlevi, et al. 2007. HDAC6 rescues neurodegeneration and provides an essential link between autophagy and the UPS. Nature 447 : 859 863.
-
(2007)
Nature
, vol.447
, pp. 859-863
-
-
Pandey, U.B.1
Nie, Z.2
Batlevi, Y.3
-
72
-
-
6344275803
-
Activation of chaperone-mediated autophagy during oxidative stress
-
Kiffin, R., C. Christian, E. Knecht, et al. 2004. Activation of chaperone-mediated autophagy during oxidative stress. Mol. Biol. Cell. 15 : 4829 4834.
-
(2004)
Mol. Biol. Cell.
, vol.15
, pp. 4829-4834
-
-
Kiffin, R.1
Christian, C.2
Knecht, E.3
-
73
-
-
25444483066
-
Lithium induces autophagy by inhibiting inositol monophosphatase
-
Sarkar, S. R.A. Floto, Z. Berger, et al. 2005. Lithium induces autophagy by inhibiting inositol monophosphatase. J. Cell. Biol. 170 : 1101 1111.
-
(2005)
J. Cell. Biol.
, vol.170
, pp. 1101-1111
-
-
Floto, A.R.S.S.1
Berger, Z.2
-
76
-
-
37849042536
-
A rational mechanism for combination treatment of Huntington's disease using lithium and rapamycin
-
E-pub ahead of print.
-
Sarkar, S., G. Krishna, S. Imarisio, et al. 2007. A rational mechanism for combination treatment of Huntington's disease using lithium and rapamycin. Hum. Mol Genet. E-pub ahead of print.
-
(2007)
Hum. Mol Genet.
-
-
Sarkar, S.1
Krishna, G.2
Imarisio, S.3
-
77
-
-
33746810059
-
Amphetamine neurotoxicity: Cause and consequence of oxidative stress
-
&
-
Yamamoto B.K. & M.G. Bankson. 2005. Amphetamine neurotoxicity: cause and consequence of oxidative stress. Crit. Rev. Neurobiol. 17 : 87 117.
-
(2005)
Crit. Rev. Neurobiol.
, vol.17
, pp. 87-117
-
-
Yamamoto, B.K.1
Bankson, M.G.2
-
78
-
-
33845353404
-
Mitochondriopathy in Parkinson disease and amyotrophic lateral sclerosis
-
Martin, L.J. 2006. Mitochondriopathy in Parkinson disease and amyotrophic lateral sclerosis. J. Neuropathol. Exp. Neurol. 65 : 1103 1110.
-
(2006)
J. Neuropathol. Exp. Neurol.
, vol.65
, pp. 1103-1110
-
-
Martin, L.J.1
-
79
-
-
34249090719
-
Lithium increases PGC-1alpha expression and mitochondrial biogenesis in primary bovine aortic endothelial cells
-
Struewing, I.T., C.D. Barnett, T. Tang, et al. 2007. Lithium increases PGC-1alpha expression and mitochondrial biogenesis in primary bovine aortic endothelial cells. FEBS J. 274 : 2749 2765.
-
(2007)
FEBS J.
, vol.274
, pp. 2749-2765
-
-
Struewing, I.T.1
Barnett, C.D.2
Tang, T.3
|