Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis

Science

Volumn 314, Issue 5796, 2006, Pages 130-133

  Neumann, Manuela ^a,f   Sampathu, Deepak M ^a   Kwong, Linda K ^a   Truax, Adam C ^a   Micsenyi, Matthew C ^a   Chou, Thomas T ^a   Bruce, Jennifer ^a   Schuck, Theresa ^a   Grossman, Murray ^a   Clark, Christopher M ^a   McCluskey, Leo F ^a   Miller, Bruce L ^b   Masliah, Eliezer ^c   Mackenzie, Ian R ^d   Feldman, Howard ^d   Feiden, Wolfgang ^e   Kretzschmar, Hans A ^f   Trojanowski, John Q ^a   Lee, Virginia M Y ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^e SAARLAND UNIVERSITY   (Germany)

^f UNIVERSITY OF MUNICH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

AMYOTROPHIC LATERAL SCLEROSIS; FRONTOTEMPORAL LOBAR DEGENERATION; NEURODEGENERATIVE DISORDERS; UBIQUITINATED PROTEIN;

DISEASES; MUSCULOSKELETAL SYSTEM; NEUROLOGY; PATHOLOGY; PROTEINS;

GENETIC ENGINEERING;

ALPHA SYNUCLEIN; DNA; DNA BINDING PROTEIN; GENE PRODUCT; GLYCINE; PROTEIN TDP 43; RNA; TAU PROTEIN; UBIQUITIN; UNCLASSIFIED DRUG; UREA;

NERVOUS SYSTEM DISORDER; NEUROLOGY; PATHOLOGY;

AMINO ACID SEQUENCE; AMYOTROPHIC LATERAL SCLEROSIS; ARTICLE; CELL INCLUSION; CONTROLLED STUDY; DEGENERATIVE DISEASE; FRONTAL CORTEX; FRONTOTEMPORAL DEMENTIA; FRONTOTEMPORAL LOBE DEMENTIA; HIPPOCAMPUS; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IMMUNOPRECIPITATION; LIQUID CHROMATOGRAPHY; NEOCORTEX; NUCLEOTIDE SEQUENCE; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DEGRADATION; PROTEIN PHOSPHORYLATION; SPINAL CORD; TANDEM MASS SPECTROMETRY; TEMPORAL CORTEX; UBIQUITINATION;

AMINO ACID SEQUENCE; AMYOTROPHIC LATERAL SCLEROSIS; ANTIBODIES, MONOCLONAL; BRAIN CHEMISTRY; CEREBRAL CORTEX; DEMENTIA; DNA-BINDING PROTEINS; FLUORESCENT ANTIBODY TECHNIQUE; HIPPOCAMPUS; HUMANS; IMMUNOBLOTTING; MOLECULAR SEQUENCE DATA; MOTOR NEURONS; NEURONS; PEPTIDE FRAGMENTS; PHOSPHORYLATION; SPINAL CORD; UBIQUITIN;

EID: 33749632259     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1134108     Document Type: Article

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