dnc-1/dynactin 1 Knockdown Disrupts Transport of Autophagosomes and Induces Motor Neuron Degeneration

PLoS ONE

Volumn 8, Issue 2, 2013, Pages

  Ikenaka, Kensuke ^a   Kawai, Kaori ^a   Katsuno, Masahisa ^a   Huang, Zhe ^a   Jiang, Yue Mei ^a   Iguchi, Yohei ^a   Kobayashi, Kyogo ^b   Kimata, Tsubasa ^b   Waza, Masahiro ^a   Tanaka, Fumiaki ^a   Mori, Ikue ^b   Sobue, Gen ^a,c  

^a NAGOYA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b NAGOYA UNIVERSITY   (Japan)

^c JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

DYNACTIN; DYNACTIN 1; RAPAMYCIN; TRICHOSTATIN A; UNCLASSIFIED DRUG;

ADULT; AMYOTROPHIC LATERAL SCLEROSIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUTOPHAGOSOME; CAENORHABDITIS ELEGANS; CELL TRANSPORT; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; GENE SILENCING; HUMAN; HUMAN TISSUE; MALE; MOTONEURON; MOTOR NEURON DEGENERATION; MOTOR NEURON DISEASE; NERVE FIBER DEGENERATION; NERVE FIBER TRANSPORT; NONHUMAN; PHENOTYPE; PROTEIN DEPLETION; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS;

ANIMALS; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; HUMANS; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; MICROSCOPY, ELECTRON; MICROTUBULE-ASSOCIATED PROTEINS; MODELS, BIOLOGICAL; MOTOR NEURONS; PHAGOSOMES;

EID: 84873591088     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0054511     Document Type: Article

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