메뉴 건너뛰기




Volumn 391, Issue 1, 1998, Pages 64-77

Time course of neuropathology in the spinal cord of G86R superoxide dismutase transgenic mice

Author keywords

Amyotrophic lateral sclerosis; Astrocytes; Electron microscopy; Interneurons; Motor neurons

Indexed keywords

SUPEROXIDE DISMUTASE;

EID: 0032472831     PISSN: 00219967     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1096-9861(19980202)391:1<64::AID-CNE6>3.0.CO;2-P     Document Type: Article
Times cited : (92)

References (45)
  • 2
    • 0027946813 scopus 로고
    • The role of calcium-binding proteins in selective motoneuron vulnerability in amyotrophic lateral sclerosis
    • Alexianu, M.E., B.-K. Ho, A.H. Mohamed, V. La Bella, R.G. Smith, and S.H. Appel (1994) The role of calcium-binding proteins in selective motoneuron vulnerability in amyotrophic lateral sclerosis. Ann. Neurol. 36:846-858.
    • (1994) Ann. Neurol. , vol.36 , pp. 846-858
    • Alexianu, M.E.1    Ho, B.-K.2    Mohamed, A.H.3    La Bella, V.4    Smith, R.G.5    Appel, S.H.6
  • 3
    • 0023809302 scopus 로고
    • Down's syndrome: Abnormal neuromuscular junction in tongue of transgenic mice with elevated levels of human Cu/Zn-superoxide dismutase
    • Avraham, K.B., M. Schickler, D. Sapoznikov, R. Yarom, and Y. Groner (1988) Down's syndrome: Abnormal neuromuscular junction in tongue of transgenic mice with elevated levels of human Cu/Zn-superoxide dismutase. Cell 54:823-829.
    • (1988) Cell , vol.54 , pp. 823-829
    • Avraham, K.B.1    Schickler, M.2    Sapoznikov, D.3    Yarom, R.4    Groner, Y.5
  • 5
    • 0027440584 scopus 로고
    • The use of the optical disector to estimate the number of neurons, glial and endothelial cells in the spinal cord of the mouse - with a comparative note on the rat spinal cord
    • Bjugn, R. (1993) The use of the optical disector to estimate the number of neurons, glial and endothelial cells in the spinal cord of the mouse - with a comparative note on the rat spinal cord. Brain Res. 627:25-33.
    • (1993) Brain Res. , vol.627 , pp. 25-33
    • Bjugn, R.1
  • 6
    • 0027500127 scopus 로고
    • Estimate of the total number of neurons and glial and endothelial cells in the rat spinal cord by means of the optical disector
    • Bjugn, R., and H.J.G. Gundersen (1993) Estimate of the total number of neurons and glial and endothelial cells in the rat spinal cord by means of the optical disector. J. Comp. Neurol. 325:406-414.
    • (1993) J. Comp. Neurol. , vol.325 , pp. 406-414
    • Bjugn, R.1    Gundersen, H.J.G.2
  • 9
    • 0030806228 scopus 로고    scopus 로고
    • Elevated free nitrotyrosine levels, but not protein-bound nitrotyrosine or hydroxyl radicals, throughout amyotrophic lateral sclerosis (ALS)-like disease implicate tyrosine nitration as an aberrant in vivo property of one familial ALS-linked superoxide dismutase 1 mutant
    • Bruijn, L.I., M.F. Beal, M.W. Becher, J.B. Schulz, P.C. Wong, D.L. Price, and D.W. Cleveland (1997) Elevated free nitrotyrosine levels, but not protein-bound nitrotyrosine or hydroxyl radicals, throughout amyotrophic lateral sclerosis (ALS)-like disease implicate tyrosine nitration as an aberrant in vivo property of one familial ALS-linked superoxide dismutase 1 mutant. Proc. Natl. Acad. Sci. USA 94:7606-7611.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 7606-7611
    • Bruijn, L.I.1    Beal, M.F.2    Becher, M.W.3    Schulz, J.B.4    Wong, P.C.5    Price, D.L.6    Cleveland, D.W.7
  • 12
    • 0027465098 scopus 로고
    • Progressive neuronopathy in transgenic mice expressing the human neurofilament heavy gene: A mouse model of amyotrophic lateral sclerosis
    • Cote, F., J.-F. Collard, and J.-P. Julien (1993) Progressive neuronopathy in transgenic mice expressing the human neurofilament heavy gene: A mouse model of amyotrophic lateral sclerosis. Cell 73:35-46.
    • (1993) Cell , vol.73 , pp. 35-46
    • Cote, F.1    Collard, J.-F.2    Julien, J.-P.3
  • 13
    • 0028933344 scopus 로고
    • Neuropathological changes in two lines of mice carrying a transgene for mutant human Cu, Zn SOD, and in mice overexpressing wild type human SOD: A model of familial amyotrophic lateral sclerosis (FALS)
    • Dal Canto, M.C., and M.E. Gurney (1995) Neuropathological changes in two lines of mice carrying a transgene for mutant human Cu, Zn SOD, and in mice overexpressing wild type human SOD: A model of familial amyotrophic lateral sclerosis (FALS). Brain Res. 676:25-40.
    • (1995) Brain Res. , vol.676 , pp. 25-40
    • Dal Canto, M.C.1    Gurney, M.E.2
  • 14
    • 0030916609 scopus 로고    scopus 로고
    • A low expressing line of transgenic mice carrying a mutant human Cu,Zn superoxide dismutase (SOD1) gene develops pathologic changes that most closely resemble those in human amyotrophic lateral sclerosis
    • Dal Canto, M.C., and M.E. Gurney (1997) A low expressing line of transgenic mice carrying a mutant human Cu,Zn superoxide dismutase (SOD1) gene develops pathologic changes that most closely resemble those in human amyotrophic lateral sclerosis. Acta Neuropathol. 93:537-550.
    • (1997) Acta Neuropathol. , vol.93 , pp. 537-550
    • Dal Canto, M.C.1    Gurney, M.E.2
  • 16
    • 0028955472 scopus 로고
    • Characterization of wild-type and amyotrophic lateral sclerosis-related mutant Cu,Zn-superoxide dismutases overproduced in baculovirus-infected insect cells
    • Fujii, J., T. Myint, H.G. Seo, Y. Kayanoki, Y. Ikeda, and N. Taniguchi (1995) Characterization of wild-type and amyotrophic lateral sclerosis-related mutant Cu,Zn-superoxide dismutases overproduced in baculovirus-infected insect cells. J. Neurochem. 64:1456-1461.
    • (1995) J. Neurochem. , vol.64 , pp. 1456-1461
    • Fujii, J.1    Myint, T.2    Seo, H.G.3    Kayanoki, Y.4    Ikeda, Y.5    Taniguchi, N.6
  • 18
    • 0026042995 scopus 로고
    • Cytopathology of amyotrophic lateral sclerosis
    • L.P. Rowland (eds): New York:Raven Press,Ltd.
    • Hirano, A. (1991) Cytopathology of amyotrophic lateral sclerosis. In L.P. Rowland (eds): Amyotrophic Lateral Sclerosis and Other Motor Neuron Diseases. New York:Raven Press,Ltd., pp. 91-101.
    • (1991) Amyotrophic Lateral Sclerosis and Other Motor Neuron Diseases , pp. 91-101
    • Hirano, A.1
  • 19
    • 0021167918 scopus 로고
    • Fine structural observations of neurofilamentous changes in amyotrophic lateral sclerosis
    • Hirano, A., H. Donnenfeld, S. Sasaki, I. Nakano (1984) Fine structural observations of neurofilamentous changes in amyotrophic lateral sclerosis. J. Neuropathol. Exp. Neurol. 43:461-470.
    • (1984) J. Neuropathol. Exp. Neurol. , vol.43 , pp. 461-470
    • Hirano, A.1    Donnenfeld, H.2    Sasaki, S.3    Nakano, I.4
  • 20
    • 0014063240 scopus 로고
    • Familial amyotrophic lateral sclerosis
    • Hirano, A., L.T. Kurland, and G.P Sayre (1967) Familial amyotrophic lateral sclerosis. Arch. Neurol. 16:232-243.
    • (1967) Arch. Neurol. , vol.16 , pp. 232-243
    • Hirano, A.1    Kurland, L.T.2    Sayre, G.P.3
  • 21
    • 0029665882 scopus 로고    scopus 로고
    • Expression of calbindin-D28k in motoneuron hybrid cells after retroviral infection with calbindin-D28k cDNA prevents amyotrophic lateral sclerosis IgG-mediated toxicity
    • Ho, B.-K., M.E. Alexianu, L.V. Colom, A.H. Mohamed, F. Serrano, and S.H. Appel (1996) Expression of calbindin-D28k in motoneuron hybrid cells after retroviral infection with calbindin-D28k cDNA prevents amyotrophic lateral sclerosis IgG-mediated toxicity. Proc. Natl. Acad. Sci. USA 93:6796-6801.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 6796-6801
    • Ho, B.-K.1    Alexianu, M.E.2    Colom, L.V.3    Mohamed, A.H.4    Serrano, F.5    Appel, S.H.6
  • 22
    • 0028116467 scopus 로고
    • A mutant neurofilament subunit causes massive, selective motor neuron death: Implication for the pathogenesis of human motor neuron disease
    • Lee, M.K., J.R. Marszalek, and D.W. Cleveland (1994) A mutant neurofilament subunit causes massive, selective motor neuron death: Implication for the pathogenesis of human motor neuron disease. Neuron 13:975-988.
    • (1994) Neuron , vol.13 , pp. 975-988
    • Lee, M.K.1    Marszalek, J.R.2    Cleveland, D.W.3
  • 23
    • 0025999463 scopus 로고
    • Cytoskeletal pathology in motor neuron disease
    • L.P. Rowland (eds): New York:Raven Press, Ltd.
    • Leigh, P.N., and M. Swash (1991) Cytoskeletal pathology in motor neuron disease. In L.P. Rowland (eds): Amyotrophic Lateral Sclerosis and Other Motor Neuron Diseases. New York:Raven Press, Ltd., pp. 115-124.
    • (1991) Amyotrophic Lateral Sclerosis and Other Motor Neuron Diseases , pp. 115-124
    • Leigh, P.N.1    Swash, M.2
  • 25
    • 0029793872 scopus 로고    scopus 로고
    • Quantitative immunocytochemical analysis of the spinal cord in G86R superoxide dismutase transgenic mice: Neurochemical correlates of selective vulnerability
    • Morrison, B.M., J.W. Gordon, M.E. Ripps, and J.H. Morrison (1996) Quantitative immunocytochemical analysis of the spinal cord in G86R superoxide dismutase transgenic mice: Neurochemical correlates of selective vulnerability. J. Comp. Neurol. 373:619-631.
    • (1996) J. Comp. Neurol. , vol.373 , pp. 619-631
    • Morrison, B.M.1    Gordon, J.W.2    Ripps, M.E.3    Morrison, J.H.4
  • 26
    • 0024560042 scopus 로고
    • Evidence for sequential degeneration of the neurons in the intermediate zone of the spinal cord in amyotrophic lateral sclerosis: A topographic and quantitative investigation
    • Oyanagi, K., F. Ikuta, and Y. Horikawa (1989) Evidence for sequential degeneration of the neurons in the intermediate zone of the spinal cord in amyotrophic lateral sclerosis: A topographic and quantitative investigation. Acta Neuropathol. 77:343-349.
    • (1989) Acta Neuropathol. , vol.77 , pp. 343-349
    • Oyanagi, K.1    Ikuta, F.2    Horikawa, Y.3
  • 28
    • 0028888945 scopus 로고
    • Transgenic mice expressing an altered murine superoxide dismutase gene provide an animal model of amyotrophic lateral sclerosis
    • Ripps, M.E., G.W. Huntley, P.R. Hof, J.H. Morrison, and J.W. Gordon (1995) Transgenic mice expressing an altered murine superoxide dismutase gene provide an animal model of amyotrophic lateral sclerosis. Proc. Natl. Acad. Sci. USA 92:689-693.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 689-693
    • Ripps, M.E.1    Huntley, G.W.2    Hof, P.R.3    Morrison, J.H.4    Gordon, J.W.5
  • 30
    • 0029441620 scopus 로고
    • Excitotoxic mechanisms in the pathogenesis of Amyotrophic Lateral Sclerosis
    • G. Serratrice and T. Munsat (eds): Philadelphia: Lippincott-Raven Publishers
    • Rothstein, J.D. (1995) Excitotoxic mechanisms in the pathogenesis of Amyotrophic Lateral Sclerosis. In G. Serratrice and T. Munsat (eds): Pathogenesis and Therapy of Amyotrophic Lateral Sclerosis. Philadelphia: Lippincott-Raven Publishers, pp. 7-20.
    • (1995) Pathogenesis and Therapy of Amyotrophic Lateral Sclerosis , pp. 7-20
    • Rothstein, J.D.1
  • 31
    • 0029030610 scopus 로고
    • Selective loss of glial glutamate transporter GLT-1 in amyotrophic lateral sclerosis
    • Rothstein, J.D., M. Van Kammen, A.I. Levey, L.J. Martin, and R.W. Kuncl (1995) Selective loss of glial glutamate transporter GLT-1 in amyotrophic lateral sclerosis. Ann. Neurol. 38:73-84.
    • (1995) Ann. Neurol. , vol.38 , pp. 73-84
    • Rothstein, J.D.1    Van Kammen, M.2    Levey, A.I.3    Martin, L.J.4    Kuncl, R.W.5
  • 32
    • 0014531855 scopus 로고
    • Quantitative studies of the postnatal growth of the spinal cord and the vertebral column of the albino mouse
    • Sakla, F.B. (1969) Quantitative studies of the postnatal growth of the spinal cord and the vertebral column of the albino mouse. J. Comp. Neurol. 136:237-252.
    • (1969) J. Comp. Neurol. , vol.136 , pp. 237-252
    • Sakla, F.B.1
  • 33
    • 0029812020 scopus 로고    scopus 로고
    • Reactive astrogliosis of the spinal cord in amyotrophic lateral sclerosis
    • Schiffer, D., S. Cordera, P. Cavalla, and A. Migheli (1996) Reactive astrogliosis of the spinal cord in amyotrophic lateral sclerosis. J. Neurol. Sci. 139 (Suppl.):S27-33.
    • (1996) J. Neurol. Sci. , vol.139 , Issue.SUPPL.
    • Schiffer, D.1    Cordera, S.2    Cavalla, P.3    Migheli, A.4
  • 35
    • 0002634911 scopus 로고
    • Clinical features and differential diagnosis of classical motor neuron disease
    • A.C. Williams (ed): London: Chapman and Hall
    • Tandan, R. (1994) Clinical features and differential diagnosis of classical motor neuron disease. In A.C. Williams (ed): Motor Neuron Disease. London: Chapman and Hall, pp. 3-28.
    • (1994) Motor Neuron Disease , pp. 3-28
    • Tandan, R.1
  • 36
    • 0028325407 scopus 로고
    • Disease-specific patterns of neuronal loss in the spinal ventral horn in amyotrophic lateral sclerosis, multiple system atrophy and X-linked recessive bulbospinal neuronopathy, with special reference to the loss of small neurons in the intermediate zone
    • Terao, S., G. Sobue, Y. Hashizume, T. Mitsuma, and A. Takahashi (1994) Disease-specific patterns of neuronal loss in the spinal ventral horn in amyotrophic lateral sclerosis, multiple system atrophy and X-linked recessive bulbospinal neuronopathy, with special reference to the loss of small neurons in the intermediate zone. J. Neurol. 247:196-203.
    • (1994) J. Neurol. , vol.247 , pp. 196-203
    • Terao, S.1    Sobue, G.2    Hashizume, Y.3    Mitsuma, T.4    Takahashi, A.5
  • 38
    • 0030910404 scopus 로고    scopus 로고
    • Oxidative stress, mutant SOD1, and neurofilament pathology in transgenic mouse models of human motor neuron disease
    • Tu, P.-H., M.E. Gurney, J.-P. Julien, V.M.-Y. Lee, and J.Q. Trojanowski (1997) Oxidative stress, mutant SOD1, and neurofilament pathology in transgenic mouse models of human motor neuron disease. Lab. Invest. 76:441-456.
    • (1997) Lab. Invest. , vol.76 , pp. 441-456
    • Tu, P.-H.1    Gurney, M.E.2    Julien, J.-P.3    Lee, V.M.-Y.4    Trojanowski, J.Q.5
  • 39
    • 0029966363 scopus 로고    scopus 로고
    • Transgenic mice carrying a human mutant superoxide dismutase transgene develop neuronal cytoskeletal pathology resembling human amyotrophic lateral sclerosis lesions
    • Tu, P.-H., P. Raju, K.A. Robinson, M.E. Gurney, J.Q. Trojanowski, and V.M.-Y. Lee (1996) Transgenic mice carrying a human mutant superoxide dismutase transgene develop neuronal cytoskeletal pathology resembling human amyotrophic lateral sclerosis lesions. Proc. Natl. Acad. Sci. USA 93:3155-3160.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 3155-3160
    • Tu, P.-H.1    Raju, P.2    Robinson, K.A.3    Gurney, M.E.4    Trojanowski, J.Q.5    Lee, V.M.-Y.6
  • 40
    • 0027194462 scopus 로고
    • New stereological methods for counting neurons
    • West, M.J. (1993) New stereological methods for counting neurons. Neurobiol. Aging 14:275-285.
    • (1993) Neurobiol. Aging , vol.14 , pp. 275-285
    • West, M.J.1
  • 41
    • 0026339976 scopus 로고
    • Unbiased stereological estimation of the total number of neurons in the subdivisions of the rat hippocampus using the optical fractionator
    • West, M. J., L. Slomianka, and H.J.G. Gundersen (1991) Unbiased stereological estimation of the total number of neurons in the subdivisions of the rat hippocampus using the optical fractionator. Anat. Rec. 231:482-497.
    • (1991) Anat. Rec. , vol.231 , pp. 482-497
    • West, M.J.1    Slomianka, L.2    Gundersen, H.J.G.3
  • 43
    • 0029053881 scopus 로고
    • An adverse property of a familial ALS-linked SOD1 mutation causes motor neuron disease characterized by vacuolar degeneration of mitochondria
    • Wong, P.C., C.A. Pardo, D.R. Borchelt, M.K. Lee, N.G. Copeland, N.A. Jenkins, S.S. Sisodia, D.W. Cleveland, and D.L. Price (1995) An adverse property of a familial ALS-linked SOD1 mutation causes motor neuron disease characterized by vacuolar degeneration of mitochondria. Neuron 14:1105-1116.
    • (1995) Neuron , vol.14 , pp. 1105-1116
    • Wong, P.C.1    Pardo, C.A.2    Borchelt, D.R.3    Lee, M.K.4    Copeland, N.G.5    Jenkins, N.A.6    Sisodia, S.S.7    Cleveland, D.W.8    Price, D.L.9
  • 44
    • 0027410516 scopus 로고
    • Increased expression of neurofilament subunit NF-L produces morphological alterations that resemble the pathology of human motor neuron disease
    • Xu, Z., L.C. Cork, J.W. Griffin, and D.W. Cleveland (1993) Increased expression of neurofilament subunit NF-L produces morphological alterations that resemble the pathology of human motor neuron disease. Cell 73:23-33.
    • (1993) Cell , vol.73 , pp. 23-33
    • Xu, Z.1    Cork, L.C.2    Griffin, J.W.3    Cleveland, D.W.4
  • 45
    • 0029939471 scopus 로고    scopus 로고
    • A gain-of-function of an amyotrophic lateral sclerosis-associated Cu,Zn-superoxide dismutase mutant: An enhancement of free radical formation due to a decrease in Km for hydrogen peroxide
    • Yim, M.B., J.-H. Rang, H.-S. Yim, H.-S. Kwak, P.B. Chock, and E.R. Stadtman (1996) A gain-of-function of an amyotrophic lateral sclerosis-associated Cu,Zn-superoxide dismutase mutant: An enhancement of free radical formation due to a decrease in Km for hydrogen peroxide. Proc. Natl. Acad. Sci. USA 93:5709-5714.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 5709-5714
    • Yim, M.B.1    Rang, J.-H.2    Yim, H.-S.3    Kwak, H.-S.4    Chock, P.B.5    Stadtman, E.R.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.