Endosomal accumulation of APP in wobbler motor neurons reflects impaired vesicle trafficking: Implications for human motor neuron disease

BMC Neuroscience

Volumn 12, Issue , 2011, Pages

  Palmisano, Ralf ^a   Golfi, Panagiota ^a   Heimann, Peter ^b   Shaw, Christopher ^a   Troakes, Claire ^a   Schmitt John, Thomas ^c   Bartsch, Jörg W ^a,d  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b BIELEFELD UNIVERSITY   (Germany)

^c AARHUS UNIVERSITY   (Denmark)

^d PHILIPPS UNIVERSITY MARBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID PRECURSOR PROTEIN; COPPER ZINC SUPEROXIDE DISMUTASE; MEMBRANE PROTEIN; RAB7 PROTEIN; UNCLASSIFIED DRUG; VPS54 PROTEIN; RAB PROTEIN; SOD1 G93A PROTEIN; SUPEROXIDE DISMUTASE; VESICULAR TRANSPORT PROTEIN; VPS54 PROTEIN, HUMAN;

ADULT; AGED; AMYOTROPHIC LATERAL SCLEROSIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN STEM; CELL MIGRATION; CELL ULTRASTRUCTURE; CELL VACUOLE; CLINICAL ARTICLE; CONTROLLED STUDY; ENDOSOME; FEMALE; GENE MUTATION; HETEROZYGOSITY; HOMOZYGOSITY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MALE; MOTONEURON; MOTOR NEURON DISEASE; MOUSE; NONHUMAN; PROTEIN ANALYSIS; PROTEIN PROCESSING; SPINAL CORD; WOBBLER MOTOR NEURON; ANIMAL; C57BL MOUSE; DISEASE MODEL; GENETICS; METABOLISM; METHODOLOGY; MIDDLE AGED; MOUSE MUTANT; NERVE FIBER TRANSPORT; PATHOLOGY; PHYSIOLOGY; TRANSGENIC MOUSE; TRANSMISSION ELECTRON MICROSCOPY; ULTRASTRUCTURE;

AGED; AGED, 80 AND OVER; AMYLOID BETA-PROTEIN PRECURSOR; AMYOTROPHIC LATERAL SCLEROSIS; ANIMALS; AXONAL TRANSPORT; BRAIN STEM; DISEASE MODELS, ANIMAL; ENDOSOMES; FEMALE; HUMANS; MALE; MICE; MICE, INBRED C57BL; MICE, MUTANT STRAINS; MICE, TRANSGENIC; MICROSCOPY, ELECTRON, TRANSMISSION; MIDDLE AGED; MOTOR NEURON DISEASE; MOTOR NEURONS; RAB GTP-BINDING PROTEINS; RAB2 GTP-BINDING PROTEIN; SPINAL CORD; SUPEROXIDE DISMUTASE; VESICULAR TRANSPORT PROTEINS;

EID: 79952325543     PISSN: None     EISSN: 14712202     Source Type: Journal    
DOI: 10.1186/1471-2202-12-24     Document Type: Article

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