-
1
-
-
0027219569
-
Expression of intracellular adhesion molecule (ICAM)-1 by a subset of astrocytes in Alzheimer disease and some other degenerative neurological disorders
-
Akiyama H, Kawamata T, Yamada T, Tooyama I, Ishii T, McGeer PL. Expression of intracellular adhesion molecule (ICAM)-1 by a subset of astrocytes in Alzheimer disease and some other degenerative neurological disorders. Acta Neuropathol 1993;85:628-634.
-
(1993)
Acta Neuropathol
, vol.85
, pp. 628-634
-
-
Akiyama, H.1
Kawamata, T.2
Yamada, T.3
Tooyama, I.4
Ishii, T.5
McGeer, P.L.6
-
2
-
-
0025162755
-
Brain microglia constitutively express β-2 integrins
-
Akiyama H, McGeer PL. Brain microglia constitutively express β-2 integrins. J Neuroimmunol 1990;30:81-93.
-
(1990)
J Neuroimmunol
, vol.30
, pp. 81-93
-
-
Akiyama, H.1
McGeer, P.L.2
-
3
-
-
0035833937
-
Immune reactivity in a mouse model of familial ALS correlates with disease progression
-
Alexianu ME, Kozovska M, Appel SH. Immune reactivity in a mouse model of familial ALS correlates with disease progression. Neurology 2001;57:1282-1289.
-
(2001)
Neurology
, vol.57
, pp. 1282-1289
-
-
Alexianu, M.E.1
Kozovska, M.2
Appel, S.H.3
-
4
-
-
0035132167
-
Increased expression of the pro inflammatory enzyme cyclooxygenase-2 in amyotrophic lateral sclerosis
-
Almer G, Guegan C, Teismann P, Naini A, Rosoklija G, Hays AP, Chen C, Przedborski S. Increased expression of the pro inflammatory enzyme cyclooxygenase-2 in amyotrophic lateral sclerosis. Ann Neurol 2001;49:176-185.
-
(2001)
Ann Neurol
, vol.49
, pp. 176-185
-
-
Almer, G.1
Guegan, C.2
Teismann, P.3
Naini, A.4
Rosoklija, G.5
Hays, A.P.6
Chen, C.7
Przedborski, S.8
-
5
-
-
0033018506
-
Inducible nitric oxide synthase upregulation in a transgenic mouse model of familial amyotrophic lateral sclerosis
-
Almer G, Vukosavic S, Romero N, Przedborski S. Inducible nitric oxide synthase upregulation in a transgenic mouse model of familial amyotrophic lateral sclerosis. J Neurochem 1999;72:2415-2425.
-
(1999)
J Neurochem
, vol.72
, pp. 2415-2425
-
-
Almer, G.1
Vukosavic, S.2
Romero, N.3
Przedborski, S.4
-
7
-
-
0029010496
-
Amyotrophic lateral sclerosis associated with homozygosity for an Asp90Ala mutation in CuZn-superoxide dismutase
-
Andersen PM, Nilsson P, Ala-Hurula V, Keranen ML, Tarvainen I, Haltia T, Nilsson L, Binzer M, Forsgren L, Marklund SL. Amyotrophic lateral sclerosis associated with homozygosity for an Asp90Ala mutation in CuZn-superoxide dismutase. Nat Genet 1995;10:61-66.
-
(1995)
Nat Genet
, vol.10
, pp. 61-66
-
-
Andersen, P.M.1
Nilsson, P.2
Ala-Hurula, V.3
Keranen, M.L.4
Tarvainen, I.5
Haltia, T.6
Nilsson, L.7
Binzer, M.8
Forsgren, L.9
Marklund, S.L.10
-
8
-
-
0031444384
-
Lack of evidence for HTLV tax-rex DNA in motor neurone disease
-
Andrews WD, Alchalabi A, Garson JA. Lack of evidence for HTLV tax-rex DNA in motor neurone disease. J Neurol Sci 1997;153:86-90.
-
(1997)
J Neurol Sci
, vol.153
, pp. 86-90
-
-
Andrews, W.D.1
Alchalabi, A.2
Garson, J.A.3
-
9
-
-
0033923528
-
Detection of reverse transcriptase activity in the serum of patients with motor neurone disease
-
Andrews WD, Tuke PW, Al-Chalabi A, Gaudin P, Ijaz S, Parton MJ, Garson JA. Detection of reverse transcriptase activity in the serum of patients with motor neurone disease. J Med Virol 2000;61:527-532.
-
(2000)
J Med Virol
, vol.61
, pp. 527-532
-
-
Andrews, W.D.1
Tuke, P.W.2
Al-Chalabi, A.3
Gaudin, P.4
Ijaz, S.5
Parton, M.J.6
Garson, J.A.7
-
10
-
-
0034793858
-
Glial cells of the spinal cord and subcortical white matter upregulate nitric oxide synthase in sporadic amyotrophic lateral sclerosis
-
Anneser JMH, Cookson MR, Ince PG, Shaw PJ, Borasio GD. Glial cells of the spinal cord and subcortical white matter upregulate nitric oxide synthase in sporadic amyotrophic lateral sclerosis. Exp Neurol 2001;171:418-421.
-
(2001)
Exp Neurol
, vol.171
, pp. 418-421
-
-
Anneser, J.M.H.1
Cookson, M.R.2
Ince, P.G.3
Shaw, P.J.4
Borasio, G.D.5
-
11
-
-
0031957298
-
Mutations in the glutamate transporter EAAT2 gene do not cause abnormal EAAT2 transcripts in amyotrophic lateral sclerosis
-
Aoki M, Lin CLG, Rothstein JD, Geller BA, Hosler BA, Munsat TL, Horvitz HR, Brown RH. Mutations in the glutamate transporter EAAT2 gene do not cause abnormal EAAT2 transcripts in amyotrophic lateral sclerosis. Ann Neurol 1998;5:645-653.
-
(1998)
Ann Neurol
, vol.5
, pp. 645-653
-
-
Aoki, M.1
Lin, C.L.G.2
Rothstein, J.D.3
Geller, B.A.4
Hosler, B.A.5
Munsat, T.L.6
Horvitz, H.R.7
Brown, R.H.8
-
12
-
-
0029436559
-
Autoimmunity as an etiological factor in sporadic amyotrophic lateral sclerosis
-
Appel SH, Smith RG, Alexianu MF, Engelhardt JI, Stefani E. Autoimmunity as an etiological factor in sporadic amyotrophic lateral sclerosis. Adv Neurol 1995;68:47-57.
-
(1995)
Adv Neurol
, vol.68
, pp. 47-57
-
-
Appel, S.H.1
Smith, R.G.2
Alexianu, M.F.3
Engelhardt, J.I.4
Stefani, E.5
-
14
-
-
0344609220
-
Beneficial effects oflysine acetylsalicylate, a soluble salt of aspirin, on motor performance in a transgenic model of amyotrophic lateral sclerosis
-
Barneoud P, Curet O. Beneficial effects oflysine acetylsalicylate, a soluble salt of aspirin, on motor performance in a transgenic model of amyotrophic lateral sclerosis. Exp Neurol 1999;155:243-251.
-
(1999)
Exp Neurol
, vol.155
, pp. 243-251
-
-
Barneoud, P.1
Curet, O.2
-
15
-
-
0031015384
-
Expression and regulation of cyclooxygenase-2 in rat microglia
-
Bauer MK, Lieb K, Schulze-Osthoff K, Berger M, Gebicke-Haerter PJ, Bauer J, Fiebich BL. Expression and regulation of cyclooxygenase-2 in rat microglia. Eur J Biochem 1997;243:726-731.
-
(1997)
Eur J Biochem
, vol.243
, pp. 726-731
-
-
Bauer, M.K.1
Lieb, K.2
Schulze-Osthoff, K.3
Berger, M.4
Gebicke-Haerter, P.J.5
Bauer, J.6
Fiebich, B.L.7
-
16
-
-
0030851761
-
Increased 3-nitrotyrosine in both sporadic and familial amyotrophic lateral sclerosis
-
Beal MF, Ferrante RJ, Browne SE, Matthews RT, Lowal NW, Brown RH Jr. Increased 3-nitrotyrosine in both sporadic and familial amyotrophic lateral sclerosis. Ann Neurol 1997;42:646-654.
-
(1997)
Ann Neurol
, vol.42
, pp. 646-654
-
-
Beal, M.F.1
Ferrante, R.J.2
Browne, S.E.3
Matthews, R.T.4
Lowal, N.W.5
Brown R.H., Jr.6
-
17
-
-
0028097839
-
A controlled trial of riluzole in amyotrophic lateral sclerosis
-
Bensimon G, Lacomblez L, Meininger V, and the ALS/ Riluzole Study Group. A controlled trial of riluzole in amyotrophic lateral sclerosis. N Engl J Med 1994;330:585-591.
-
(1994)
N Engl J Med
, vol.330
, pp. 585-591
-
-
Bensimon, G.1
Lacomblez, L.2
Meininger, V.3
-
18
-
-
0033981056
-
Detection and cellular localization of enterovirus RNA sequence in spinal cord of patients with ALS
-
Berger MM, Kopp N, Vital C, Redl B, Aymard M, Lina B. Detection and cellular localization of enterovirus RNA sequence in spinal cord of patients with ALS. Neurology 2000;54:20-25.
-
(2000)
Neurology
, vol.54
, pp. 20-25
-
-
Berger, M.M.1
Kopp, N.2
Vital, C.3
Redl, B.4
Aymard, M.5
Lina, B.6
-
19
-
-
0031868461
-
Elevated "hydroxyl radical" generation in vivo in an animal model of amyotrophic lateral sclerosis
-
Bogdanov MB, Ramos LE, Xu ZS, Beal MF. Elevated "hydroxyl radical" generation in vivo in an animal model of amyotrophic lateral sclerosis. J Neurochem 1998;71:1321-1324.
-
(1998)
J Neurochem
, vol.71
, pp. 1321-1324
-
-
Bogdanov, M.B.1
Ramos, L.E.2
Xu, Z.S.3
Beal, M.F.4
-
20
-
-
0025033649
-
Cellular immune reaction in multiple sclerosis plaques
-
Boyle EA, McGeer PL. Cellular immune reaction in multiple sclerosis plaques. Am J Pathol 1990;137:575-584.
-
(1990)
Am J Pathol
, vol.137
, pp. 575-584
-
-
Boyle, E.A.1
McGeer, P.L.2
-
21
-
-
0032544674
-
Aggregation and motor neuron toxicity of an ALS-linked SOD1 mutant independent from wild-type SOD1
-
Bruijn LI, Houseweart MK, Kato S, Anderson KL, Anderson SD, Ohama E, Reaume AG, Scott RW, Cleveland DW. Aggregation and motor neuron toxicity of an ALS-linked SOD1 mutant independent from wild-type SOD1. Science 1998;281:1851-1854.
-
(1998)
Science
, vol.281
, pp. 1851-1854
-
-
Bruijn, L.I.1
Houseweart, M.K.2
Kato, S.3
Anderson, K.L.4
Anderson, S.D.5
Ohama, E.6
Reaume, A.G.7
Scott, R.W.8
Cleveland, D.W.9
-
22
-
-
0035880007
-
Brain protein oxidation in agerelated neurodegenerative disorders that are associated with aggregated proteins
-
Butterfield DA, Kanski J. Brain protein oxidation in agerelated neurodegenerative disorders that are associated with aggregated proteins. Mech Aging Dev 2001;122:945-962.
-
(2001)
Mech Aging Dev
, vol.122
, pp. 945-962
-
-
Butterfield, D.A.1
Kanski, J.2
-
23
-
-
0032530566
-
Transgenic mice for interleukin 3 develop motor neuron degeneration associated with autoimmune reaction against spinal cord motor neurons
-
Chavany C, Vicarioabejon C, Miller G, Jendoubi M. Transgenic mice for interleukin 3 develop motor neuron degeneration associated with autoimmune reaction against spinal cord motor neurons. Proc Natl Acad Sci U S A 1998;95:11354-11359.
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 11354-11359
-
-
Chavany, C.1
Vicarioabejon, C.2
Miller, G.3
Jendoubi, M.4
-
24
-
-
0032716333
-
A receptor for advanced glycosylation endproducts (AGEs) is colocalized with neurofilament-bound AGEs and SOD1 in motoneurons of ALS: Immunohistochemical study
-
Chous SM, Han CY, Wang HS, Vlassara H, Bucala R. A receptor for advanced glycosylation endproducts (AGEs) is colocalized with neurofilament-bound AGEs and SOD1 in motoneurons of ALS: immunohistochemical study. J Neurol Sci 1999;169:87-92.
-
(1999)
J Neurol Sci
, vol.169
, pp. 87-92
-
-
Chous, S.M.1
Han, C.Y.2
Wang, H.S.3
Vlassara, H.4
Bucala, R.5
-
25
-
-
10244256425
-
Mechanisms of selective motor neuron death in transgenic mouse models of motor neuron disease
-
Cleveland DW, Bruijn LI, Wong PC, Marszalek JR, Vechio JD, Lee MK, Xu XS, Borchelt DR, Sisodia SS, Price DL. Mechanisms of selective motor neuron death in transgenic mouse models of motor neuron disease. Neurology 1996;47(4 Suppl 2):S54-S61.
-
(1996)
Neurology
, vol.47
, Issue.4 SUPPL. 2
-
-
Cleveland, D.W.1
Bruijn, L.I.2
Wong, P.C.3
Marszalek, J.R.4
Vechio, J.D.5
Lee, M.K.6
Xu, X.S.7
Borchelt, D.R.8
Sisodia, S.S.9
Price, D.L.10
-
26
-
-
0035516124
-
From Charcot to Lou Gehrig: Deciphering selective motor neuron death in ALS
-
Cleveland DW, Rothstein JD. From Charcot to Lou Gehrig: deciphering selective motor neuron death in ALS. Nat Rev 2001;2:806-819.
-
(2001)
Nat Rev
, vol.2
, pp. 806-819
-
-
Cleveland, D.W.1
Rothstein, J.D.2
-
27
-
-
0023642584
-
Production of superoxide anions by a CNS macrophage, the microglia
-
Colton CA, Gilbert DI. Production of superoxide anions by a CNS macrophage, the microglia. FEBS Lett 1987;223:284-288.
-
(1987)
FEBS Lett
, vol.223
, pp. 284-288
-
-
Colton, C.A.1
Gilbert, D.I.2
-
28
-
-
0032568546
-
Chaperonefacilitated copper binding is a property common to several classes of familial amyotrophic lateral sclerosis-linked superoxide dismutase mutants
-
Corson LB, Strain JJ, Culotta VC, Cleveland DW. Chaperonefacilitated copper binding is a property common to several classes of familial amyotrophic lateral sclerosis-linked superoxide dismutase mutants. Proc Natl Acad Sci U S A 1998;95:6261-6366.
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 6261-6366
-
-
Corson, L.B.1
Strain, J.J.2
Culotta, V.C.3
Cleveland, D.W.4
-
29
-
-
0028933344
-
Neuropathological changes in two lines of mice carrying a transgene for mutant human Cu.Zn SOD, and in mice overexpressing wild type human SOD: A model of familial amyotrophic lateral sclerosis (FALS)
-
Dal Canto MC, Gurney ME. Neuropathological changes in two lines of mice carrying a transgene for mutant human Cu.Zn SOD, and in mice overexpressing wild type human SOD: a model of familial amyotrophic lateral sclerosis (FALS). Brain Res 1995;676:25-40.
-
(1995)
Brain Res
, vol.676
, pp. 25-40
-
-
Dal Canto, M.C.1
Gurney, M.E.2
-
31
-
-
0003136104
-
El 'tercer elemento' de los centros nerviosos. Poder fagocitario y movilidad de la microglia
-
Del Rio Hortega P. El 'tercer elemento' de los centros nerviosos. Poder fagocitario y movilidad de la microglia. Bol Soc Esp Biol Ano 1919;9:154-166.
-
(1919)
Bol Soc Esp Biol Ano
, vol.9
, pp. 154-166
-
-
Del Rio Hortega, P.1
-
32
-
-
0035007860
-
A double-blind, placebo-controlled randomized clinical trial of alphatocopherol (vitamin E) in the treatment of amyotrophic lateral sclerosis (ALS)
-
Desnuelle C, Dib M, Garrel C, Favier A. A double-blind, placebo-controlled randomized clinical trial of alphatocopherol (vitamin E) in the treatment of amyotrophic lateral sclerosis (ALS). Amyotroph Lat Scler Other Motor Neuron Disord 2001;2:9-18.
-
(2001)
Amyotroph Lat Scler Other Motor Neuron Disord
, vol.2
, pp. 9-18
-
-
Desnuelle, C.1
Dib, M.2
Garrel, C.3
Favier, A.4
-
33
-
-
0342621602
-
Does autoimmunity play a role in amyotrophic lateral sclerosis?
-
Braus RH Jr, Meininger V, Swash M, editors. London: Martin Dunitz
-
Drachman DB. Does autoimmunity play a role in amyotrophic lateral sclerosis? In: Braus RH Jr, Meininger V, Swash M, editors. Amyotrophic lateral sclerosis. London: Martin Dunitz; 2000. p 309-316.
-
(2000)
Amyotrophic lateral sclerosis
, pp. 309-316
-
-
Drachman, D.B.1
-
34
-
-
0033762974
-
Inhibition of cyclooxygenase-2 protects motor neurons in an organotypic model of amyotrophic lateral sclerosis
-
Drachman DB, Rothstein JD. Inhibition of cyclooxygenase-2 protects motor neurons in an organotypic model of amyotrophic lateral sclerosis. Ann Neurol 2000;48:792-795.
-
(2000)
Ann Neurol
, vol.48
, pp. 792-795
-
-
Drachman, D.B.1
Rothstein, J.D.2
-
35
-
-
0027759524
-
Anti-glutamate therapy in amyotrophic lateral sclerosis: A trial using lamotrigine
-
Eisen A, Steward H, Schulzer M, Cameron D. Anti-glutamate therapy in amyotrophic lateral sclerosis: a trial using lamotrigine. J Can Sci Neurol 1993;20:297-301.
-
(1993)
J Can Sci Neurol
, vol.20
, pp. 297-301
-
-
Eisen, A.1
Steward, H.2
Schulzer, M.3
Cameron, D.4
-
37
-
-
0025319048
-
Motor neuron destruction in guinea pigs immunized with bovine spinal cord ventral horn homogenate: Experimental autoimmune gray matter disease
-
Engelhardt JI, Appel SH, Killian JM. Motor neuron destruction in guinea pigs immunized with bovine spinal cord ventral horn homogenate: experimental autoimmune gray matter disease. J Neuroimmunol 1990;27:21-31.
-
(1990)
J Neuroimmunol
, vol.27
, pp. 21-31
-
-
Engelhardt, J.I.1
Appel, S.H.2
Killian, J.M.3
-
38
-
-
0027473452
-
Lymphocytic infiltrates in the spinal cord in amyotrophic lateral sclerosis
-
Engelhardt JI, Tajti J, Appel SH. Lymphocytic infiltrates in the spinal cord in amyotrophic lateral sclerosis. Arch Neurol 1993;50:30-36.
-
(1993)
Arch Neurol
, vol.50
, pp. 30-36
-
-
Engelhardt, J.I.1
Tajti, J.2
Appel, S.H.3
-
39
-
-
0034773568
-
Presymptomatic motor neuron loss and reactive astrocytosis in the SOD1 mouse model of amyotrophic lateral sclerosis
-
Feeney SJ, McKelvie PA, Austin L, Jean-Francois MJB, Kapsa R, Tombs SM, Byrne E. Presymptomatic motor neuron loss and reactive astrocytosis in the SOD1 mouse model of amyotrophic lateral sclerosis. Muscle Nerve 2001;24:1510-1519.
-
(2001)
Muscle Nerve
, vol.24
, pp. 1510-1519
-
-
Feeney, S.J.1
McKelvie, P.A.2
Austin, L.3
Jean-Francois, M.J.B.4
Kapsa, R.5
Tombs, S.M.6
Byrne, E.7
-
40
-
-
0030813067
-
Evidence of increased oxidative damage in both sporadic and familial amyotrophic lateral sclerosis
-
Ferrante RJ, Browne SE, Shinobu LA, Bowling AC, Baik MJ, Macgarvey U, Kowall NW, Brown RH, Beal MF. Evidence of increased oxidative damage in both sporadic and familial amyotrophic lateral sclerosis. J Neurochem 1997;69:2064-2074.
-
(1997)
J Neurochem
, vol.69
, pp. 2064-2074
-
-
Ferrante, R.J.1
Browne, S.E.2
Shinobu, L.A.3
Bowling, A.C.4
Baik, M.J.5
Macgarvey, U.6
Kowall, N.W.7
Brown, R.H.8
Beal, M.F.9
-
41
-
-
0030767498
-
Increased 3-nitrotyrosine and oxidative damage in mice with a human copper/zinc superoxide dismutase mutation
-
Ferrante RJ, Shinobu LA, Schulz JB, Matthews RT, Thomas CE, Kowall NW, Gurney ME, Beal ME. Increased 3-nitrotyrosine and oxidative damage in mice with a human copper/zinc superoxide dismutase mutation. Ann Neurol 1997;42:326-334.
-
(1997)
Ann Neurol
, vol.42
, pp. 326-334
-
-
Ferrante, R.J.1
Shinobu, L.A.2
Schulz, J.B.3
Matthews, R.T.4
Thomas, C.E.5
Kowall, N.W.6
Gurney, M.E.7
Beal, M.E.8
-
43
-
-
0029893001
-
Mouse innoculation studies reveal no transmissible agent in amyotrophic lateral sclerosis
-
Fraser H, Behan W, Chree A, Crossland G, Behan P. Mouse innoculation studies reveal no transmissible agent in amyotrophic lateral sclerosis. Brain Pathol 1996;6:89-99.
-
(1996)
Brain Pathol
, vol.6
, pp. 89-99
-
-
Fraser, H.1
Behan, W.2
Chree, A.3
Crossland, G.4
Behan, P.5
-
44
-
-
0034015718
-
Amyotrophic lateral sclerosis: A role for enteroviruses?
-
Giraud P, Kopp N, Lina B, Chazot G. Amyotrophic lateral sclerosis: a role for enteroviruses? Rev Neurol 2000;156:352-356.
-
(2000)
Rev Neurol
, vol.156
, pp. 352-356
-
-
Giraud, P.1
Kopp, N.2
Lina, B.3
Chazot, G.4
-
45
-
-
0029811105
-
Specific domains of β-amyloid from Alzheimer plaque elicit neuronal killing in human microglia
-
Giulian D, Haverkamp LJ, Yu JH, Harshin WL, Li J, Kirkpatrick J, Kuo Y-M, Roher AE. Specific domains of β-amyloid from Alzheimer plaque elicit neuronal killing in human microglia. J Neurosci 1996;16:6021-6037.
-
(1996)
J Neurosci
, vol.16
, pp. 6021-6037
-
-
Giulian, D.1
Haverkamp, L.J.2
Yu, J.H.3
Harshin, W.L.4
Li, J.5
Kirkpatrick, J.6
Kuo, Y.-M.7
Roher, A.E.8
-
46
-
-
0025609978
-
Secretion of neurotoxins by mononuclear phagocytes infected with HIV-1
-
Giulian D, Vaca K, Noonan CA. Secretion of neurotoxins by mononuclear phagocytes infected with HIV-1. Science 1990;250:1593-1596.
-
(1990)
Science
, vol.250
, pp. 1593-1596
-
-
Giulian, D.1
Vaca, K.2
Noonan, C.A.3
-
48
-
-
0033551794
-
ClqB and clusterin mRNA increase in association with neurodegeneration in sporadic amyotrophic lateral sclerosis
-
Grewal RP, Morgan TE, Finch CE. ClqB and clusterin mRNA increase in association with neurodegeneration in sporadic amyotrophic lateral sclerosis. Neurosci Lett 1999;271:65-67.
-
(1999)
Neurosci Lett
, vol.271
, pp. 65-67
-
-
Grewal, R.P.1
Morgan, T.E.2
Finch, C.E.3
-
49
-
-
0030050727
-
Benefit of vitamin E, riluzole and gabapentin in a transgenic model of familial amyotrophic lateral sclerosis
-
Gurney ME, Cutting FB, Zhai P, Doble A, Taylor CP, Andrus PK, Hall ED. Benefit of vitamin E, riluzole and gabapentin in a transgenic model of familial amyotrophic lateral sclerosis. Ann Neurol 1996;39:147-157.
-
(1996)
Ann Neurol
, vol.39
, pp. 147-157
-
-
Gurney, M.E.1
Cutting, F.B.2
Zhai, P.3
Doble, A.4
Taylor, C.P.5
Andrus, P.K.6
Hall, E.D.7
-
50
-
-
0028284779
-
Motor neuron degeneration in mice that express a human Cu, Zn superoxide dismutase mutation
-
Gurney ME, Pu H, Chiu AY, Dal Canto MC, Polchow CY, Alexander DD, Caliendo J, Hentati A, Kwon YW, Deng HX. Motor neuron degeneration in mice that express a human Cu, Zn superoxide dismutase mutation. Science 1994;264:1772-1775.
-
(1994)
Science
, vol.264
, pp. 1772-1775
-
-
Gurney, M.E.1
Pu, H.2
Chiu, A.Y.3
Dal Canto, M.C.4
Polchow, C.Y.5
Alexander, D.D.6
Caliendo, J.7
Hentati, A.8
Kwon, Y.W.9
Deng, H.X.10
-
51
-
-
0034785483
-
A gene encoding a putative GTPase regulator is mutated in familial amyotrophic lateral sclerosis 2
-
Hadano S, Hand CK, Osuga H, Yanagisawa Y, Otomo A, Devon RS, Miyamoto N, Showguchi-Miyata J, Okada Y, Singaraja R, Figlewicz DA, Kwiatkowski T, Hosler BA, Sagie T, Skaug J, Nasir J, Brown RH Jr, Scherer SW, Rouleau GA, Hayden MR, Ikeda J-E. A gene encoding a putative GTPase regulator is mutated in familial amyotrophic lateral sclerosis 2. Nat Genet 2001;29:166-173.
-
(2001)
Nat Genet
, vol.29
, pp. 166-173
-
-
Hadano, S.1
Hand, C.K.2
Osuga, H.3
Yanagisawa, Y.4
Otomo, A.5
Devon, R.S.6
Miyamoto, N.7
Showguchi-Miyata, J.8
Okada, Y.9
Singaraja, R.10
Figlewicz, D.A.11
Kwiatkowski, T.12
Hosler, B.A.13
Sagie, T.14
Skaug, J.15
Nasir, J.16
Brown R.H., Jr.17
Scherer, S.W.18
Rouleau, G.A.19
Hayden, M.R.20
Ikeda, J.-E.21
more..
-
52
-
-
0032127330
-
Relationship of oxygen radical-induced lipid peroxidative damage to disease onset and progression in a transgenic model of familial ALS
-
Hall ED, Andrus PK, Oostveen JA, Fleck TJ, Gurney ME. Relationship of oxygen radical-induced lipid peroxidative damage to disease onset and progression in a transgenic model of familial ALS. J Neurosci Res 1998;53:66-77.
-
(1998)
J Neurosci Res
, vol.53
, pp. 66-77
-
-
Hall, E.D.1
Andrus, P.K.2
Oostveen, J.A.3
Fleck, T.J.4
Gurney, M.E.5
-
53
-
-
0032125587
-
Relationship of microglial and astrocytic activation to disease onset and progression in a transgenic model of familial ALS
-
Hall ED, Ooseveen JA, Gurney ME. Relationship of microglial and astrocytic activation to disease onset and progression in a transgenic model of familial ALS. Glia 1998;23:249-256
-
(1998)
Glia
, vol.23
, pp. 249-256
-
-
Hall, E.D.1
Ooseveen, J.A.2
Gurney, M.E.3
-
55
-
-
0033009789
-
Molecular genetic analysis of the APEX nuclease gene in amyotrophic lateral sclerosis
-
Hayward C, Colville S, Swingler RJ, Brock DJH. Molecular genetic analysis of the APEX nuclease gene in amyotrophic lateral sclerosis. Neurology 1999;52:1899-1901.
-
(1999)
Neurology
, vol.52
, pp. 1899-1901
-
-
Hayward, C.1
Colville, S.2
Swingler, R.J.3
Brock, D.J.H.4
-
56
-
-
0025981021
-
T-lymphocyte entry into the central nervous system
-
Hickey WF, Hsu BL, Kimura H. T-lymphocyte entry into the central nervous system. J Neurosci Res 1991;28:254-260.
-
(1991)
J Neurosci Res
, vol.28
, pp. 254-260
-
-
Hickey, W.F.1
Hsu, B.L.2
Kimura, H.3
-
57
-
-
0030820955
-
Increased levels of cyclooxygenase-2 mRNA in the rat spinal cord after peripheral inflammation: An in situ hybridization study
-
Ichitani Y, Shi T, Haeggstrom JZ, Samuelsson B, Hokfelt T. Increased levels of cyclooxygenase-2 mRNA in the rat spinal cord after peripheral inflammation: an in situ hybridization study. Neuroreport 1997;8:2949-2952.
-
(1997)
Neuroreport
, vol.8
, pp. 2949-2952
-
-
Ichitani, Y.1
Shi, T.2
Haeggstrom, J.Z.3
Samuelsson, B.4
Hokfelt, T.5
-
58
-
-
0028916910
-
Superoxide dismutase mutations in an unselected cohort of Scottish amyotrophic lateral sclerosis patients
-
Jones CT, Swingler RJ, Simpson SA, Brock DJH. Superoxide dismutase mutations in an unselected cohort of Scottish amyotrophic lateral sclerosis patients. J Med Genet 1995;32:290-292.
-
(1995)
J Med Genet
, vol.32
, pp. 290-292
-
-
Jones, C.T.1
Swingler, R.J.2
Simpson, S.A.3
Brock, D.J.H.4
-
59
-
-
0029840428
-
Familial amyotrophic lateral sclerosis with a two base pair deletion in superoxide dismutase 1 gene: Multisystem degeneration with intracytoplasmic hyaline inclusions in astrocytes
-
Kato S, Shimoda M, Watanabe Y, Nakashima K, Takahashi K, Ohama E. Familial amyotrophic lateral sclerosis with a two base pair deletion in superoxide dismutase 1 gene: multisystem degeneration with intracytoplasmic hyaline inclusions in astrocytes. J Neuropathol Exp Neurol 1996;55:1089-1101.
-
(1996)
J Neuropathol Exp Neurol
, vol.55
, pp. 1089-1101
-
-
Kato, S.1
Shimoda, M.2
Watanabe, Y.3
Nakashima, K.4
Takahashi, K.5
Ohama, E.6
-
60
-
-
0034209203
-
New consensus research on neuropathological aspects of familial amyotrophic lateral sclerosis with superoxide dismutase 1 (SOD1) gene mutations: Inclusions containing SOD1 in neurons and astrocytes
-
Kato S, Takikawa M, Nakashima K, Hirano A, Cleveland DW, Kusaka H, Shibata N, Kato M, Nakano I, Ohama E. New consensus research on neuropathological aspects of familial amyotrophic lateral sclerosis with superoxide dismutase 1 (SOD1) gene mutations: inclusions containing SOD1 in neurons and astrocytes. Amyotroph Lat Scler Other Motor Neuron Disord 2000;1:163-184.
-
(2000)
Amyotroph Lat Scler Other Motor Neuron Disord
, vol.1
, pp. 163-184
-
-
Kato, S.1
Takikawa, M.2
Nakashima, K.3
Hirano, A.4
Cleveland, D.W.5
Kusaka, H.6
Shibata, N.7
Kato, M.8
Nakano, I.9
Ohama, E.10
-
61
-
-
0026605961
-
Immunologic reactions in amyotrophic lateral sclerosis brain and spinal cord tissue
-
Kawamata T, Akiyama H, Yamada T, McGeer PL. Immunologic reactions in amyotrophic lateral sclerosis brain and spinal cord tissue. Am J Pathol 1992;140:691-707.
-
(1992)
Am J Pathol
, vol.140
, pp. 691-707
-
-
Kawamata, T.1
Akiyama, H.2
Yamada, T.3
McGeer, P.L.4
-
62
-
-
0030754962
-
4-Hydroxynonenal, an aldehydic product of membrane lipid peroxidation, impairs glutamate transport and mitochondrial function in synaptosomes
-
Keller JN, Mark RJ, Bruce AJ, Blanc E, Rothstein JD, Uchida K, Waeg G, Mattson MP. 4-Hydroxynonenal, an aldehydic product of membrane lipid peroxidation, impairs glutamate transport and mitochondrial function in synaptosomes. Neuroscience 1997;80:685-696.
-
(1997)
Neuroscience
, vol.80
, pp. 685-696
-
-
Keller, J.N.1
Mark, R.J.2
Bruce, A.J.3
Blanc, E.4
Rothstein, J.D.5
Uchida, K.6
Waeg, G.7
Mattson, M.P.8
-
63
-
-
0033980332
-
Interaction of various intrasignalling mechanisms involved in mononuclear phagocyte toxicity towards neuronal cells
-
Klegeris A, McGeer PL. Interaction of various intrasignalling mechanisms involved in mononuclear phagocyte toxicity towards neuronal cells. J Leukoc Biol 2000;67:127-133.
-
(2000)
J Leukoc Biol
, vol.67
, pp. 127-133
-
-
Klegeris, A.1
McGeer, P.L.2
-
64
-
-
0027967219
-
Rat brain microglia and peritoneal macrophages show similar responses to respiratory burst stimulants
-
Klegeris A, McGeer PL. Rat brain microglia and peritoneal macrophages show similar responses to respiratory burst stimulants. J Neuroimmunol 1994;53:83-90.
-
(1994)
J Neuroimmunol
, vol.53
, pp. 83-90
-
-
Klegeris, A.1
McGeer, P.L.2
-
65
-
-
0030774899
-
Regulation of glutamate in cultures of human monocytic THP-1 and astrocytoma U-373 MG cells
-
Klegeris A, Walker DG, McGeer PL. Regulation of glutamate in cultures of human monocytic THP-1 and astrocytoma U-373 MG cells. J Neuroimmunol 1997;78:152-161.
-
(1997)
J Neuroimmunol
, vol.78
, pp. 152-161
-
-
Klegeris, A.1
Walker, D.G.2
McGeer, P.L.3
-
66
-
-
0031012304
-
Mutations in SOD1 associated with amyotrophic lateral sclerosis cause novel protein interactions
-
Kunst CB, Mezey E, Brownstein MJ, Patterson D. Mutations in SOD1 associated with amyotrophic lateral sclerosis cause novel protein interactions. Nat Genet 1997;15:91-94.
-
(1997)
Nat Genet
, vol.15
, pp. 91-94
-
-
Kunst, C.B.1
Mezey, E.2
Brownstein, M.J.3
Patterson, D.4
-
67
-
-
0029977337
-
Dose-ranging study of riluzole in amyotrophic lateral sclerosis
-
Lacomblez L, Bensimon G, Leigh PN, Guillet P, Meininger V. Dose-ranging study of riluzole in amyotrophic lateral sclerosis. Lancet 1996;347:1425-1431.
-
(1996)
Lancet
, vol.347
, pp. 1425-1431
-
-
Lacomblez, L.1
Bensimon, G.2
Leigh, P.N.3
Guillet, P.4
Meininger, V.5
-
68
-
-
0035970036
-
Reduced susceptibility to ischemic brain injury and N-methyl-D-aspartate neurotoxicity in cyclooxygenase-2-deficient mice
-
Ladecola C, Niwa K, Nogawa S, Zhao XR, Nagayama M, Araki E, Morham S, Ross ME. Reduced susceptibility to ischemic brain injury and N-methyl-D-aspartate neurotoxicity in cyclooxygenase-2-deficient mice. Proc Natl Acad Sci U S A 2001;98:1294-1299.
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 1294-1299
-
-
Ladecola, C.1
Niwa, K.2
Nogawa, S.3
Zhao, X.R.4
Nagayama, M.5
Araki, E.6
Morham, S.7
Ross, M.E.8
-
69
-
-
0024997449
-
Major histocompatibility complex antigen expression in the affected tissues in amyotrophic lateral sclerosis
-
Lampson LA, Kushner PD, Sobel RA. Major histocompatibility complex antigen expression in the affected tissues in amyotrophic lateral sclerosis. Ann Neurol 1990;28:365-372.
-
(1990)
Ann Neurol
, vol.28
, pp. 365-372
-
-
Lampson, L.A.1
Kushner, P.D.2
Sobel, R.A.3
-
70
-
-
0034925118
-
The glial glutamate transporter, GLT-1, is oxidatively modified by 4-hydroxy-2-nonenal in the Alzheimer's disease brain: The role of A beta 1-42
-
Lauderback CM, Hackett JM, Huang FF, Keller JN, Szweda LI, Markesbery WR, Butterfield DA. The glial glutamate transporter, GLT-1, is oxidatively modified by 4-hydroxy-2-nonenal in the Alzheimer's disease brain: the role of A beta 1-42. J Neurochem 2001;78:413-416.
-
(2001)
J Neurochem
, vol.78
, pp. 413-416
-
-
Lauderback, C.M.1
Hackett, J.M.2
Huang, F.F.3
Keller, J.N.4
Szweda, L.I.5
Markesbery, W.R.6
Butterfield, D.A.7
-
71
-
-
0033485920
-
Astrocytes interact intimately with degenerating motor neurons in mouse amyotrophic lateral sclerosis (ALS)
-
Levine JB, Kong JM, Nadler M, Xu ZS. Astrocytes interact intimately with degenerating motor neurons in mouse amyotrophic lateral sclerosis (ALS). Glia 1999;28:215-224.
-
(1999)
Glia
, vol.28
, pp. 215-224
-
-
Levine, J.B.1
Kong, J.M.2
Nadler, M.3
Xu, Z.S.4
-
72
-
-
0034647003
-
Functional role of caspase-1 and caspase-3 in an ALS transgenic mouse model
-
Li M, Oan VO, Guegan C, Chen M, Jackson-Lewis V, Andrews LJ, Olszewski AJ, Stieg PE, Lee J-P, Przedborski S, Friedlander RM. Functional role of caspase-1 and caspase-3 in an ALS transgenic mouse model. Science 2000;288:335-339.
-
(2000)
Science
, vol.288
, pp. 335-339
-
-
Li, M.1
Oan, V.O.2
Guegan, C.3
Chen, M.4
Jackson-Lewis, V.5
Andrews, L.J.6
Olszewski, A.J.7
Stieg, P.E.8
Lee, J.-P.9
Przedborski, S.10
Friedlander, R.M.11
-
73
-
-
0031768025
-
Enhanced oxygen radical production in a transgenic mouse model of familial amyotrophic lateral sclerosis
-
Liu R, Althaus JS, Ellerbrock BR, Becker DA, Guerney ME. Enhanced oxygen radical production in a transgenic mouse model of familial amyotrophic lateral sclerosis. Ann Neurol 1998;44:763-770.
-
(1998)
Ann Neurol
, vol.44
, pp. 763-770
-
-
Liu, R.1
Althaus, J.S.2
Ellerbrock, B.R.3
Becker, D.A.4
Guerney, M.E.5
-
74
-
-
0029040463
-
Randomized double-blind controlled trial of acetylcysteine in amyotrophic lateral sclerosis
-
Louwerse ES, Weverling GJ, Bossuyt PM, Meyes FE, de Jong JM. Randomized double-blind controlled trial of acetylcysteine in amyotrophic lateral sclerosis. Arch Neurol 1995;52:559-564.
-
(1995)
Arch Neurol
, vol.52
, pp. 559-564
-
-
Louwerse, E.S.1
Weverling, G.J.2
Bossuyt, P.M.3
Meyes, F.E.4
De Jong, J.M.5
-
75
-
-
0023757471
-
Immune system associated antigens expressed by cells of the human central nervous system
-
Luber-Narod J, Rogers J. Immune system associated antigens expressed by cells of the human central nervous system. Neurosci Lett 1988;94:265-273.
-
(1988)
Neurosci Lett
, vol.94
, pp. 265-273
-
-
Luber-Narod, J.1
Rogers, J.2
-
76
-
-
0033927533
-
Cyclooxygenase-2 inhibitors: Rationale and therapeutic potential for Alzheimer's disease
-
McGeer PL. Cyclooxygenase-2 inhibitors: rationale and therapeutic potential for Alzheimer's disease. Drugs Aging 2000;17:1-11.
-
(2000)
Drugs Aging
, vol.17
, pp. 1-11
-
-
McGeer, P.L.1
-
77
-
-
0023782375
-
Expression of the histocompatibility glycoprotein HLA-DR in neurological disease
-
McGeer PL, Itagaki S, McGeer EG. Expression of the histocompatibility glycoprotein HLA-DR in neurological disease. Acta Neuropathol 1988;76:550-557.
-
(1988)
Acta Neuropathol
, vol.76
, pp. 550-557
-
-
McGeer, P.L.1
Itagaki, S.2
McGeer, E.G.3
-
78
-
-
0034084677
-
Autotoxicity and Alzheimer disease
-
McGeer PL, McGeer EG. Autotoxicity and Alzheimer disease. Arch Neurol 2000;57:789-790.
-
(2000)
Arch Neurol
, vol.57
, pp. 789-790
-
-
McGeer, P.L.1
McGeer, E.G.2
-
79
-
-
0035693924
-
Inflammation, autotoxicity and Alzheimer disease
-
McGeer PL, McGeer EG. Inflammation, autotoxicity and Alzheimer disease. Neurobiol Aging 2001;22:799-809.
-
(2001)
Neurobiol Aging
, vol.22
, pp. 799-809
-
-
McGeer, P.L.1
McGeer, E.G.2
-
80
-
-
0029610011
-
The inflammatory response system of brain: Implications for therapy of Alzheimer and other neurodegenerative disease
-
McGeer PL, McGeer EG. The inflammatory response system of brain: implications for therapy of Alzheimer and other neurodegenerative disease. Brain Res Rev 1995;21:195-218.
-
(1995)
Brain Res Rev
, vol.21
, pp. 195-218
-
-
McGeer, P.L.1
McGeer, E.G.2
-
83
-
-
0035836649
-
Phase III randomized trial of gabapentin in patients with amyotrophic lateral sclerosis
-
Miller RG, Moore D, Gelinas DF, Dronsky V, Mendoza M, Barohn RJ, Bryan W, Ravits J, Yuen E, Neville H, Ringel S, Bromberg M, Petajan J, Amato AA, Jaclson C, Johnson W, Mandler R, Bosch P, Smith B, Graves M, Ross M, Sorenson EJ, Kelkar P, Parry G, Olney R. Phase III randomized trial of gabapentin in patients with amyotrophic lateral sclerosis. Neurology 2001;56:843-858.
-
(2001)
Neurology
, vol.56
, pp. 843-858
-
-
Miller, R.G.1
Moore, D.2
Gelinas, D.F.3
Dronsky, V.4
Mendoza, M.5
Barohn, R.J.6
Bryan, W.7
Ravits, J.8
Yuen, E.9
Neville, H.10
Ringel, S.11
Bromberg, M.12
Petajan, J.13
Amato, A.A.14
Jaclson, C.15
Johnson, W.16
Mandler, R.17
Bosch, P.18
Smith, B.19
Graves, M.20
Ross, M.21
Sorenson, E.J.22
Kelkar, P.23
Parry, G.24
Olney, R.25
more..
-
84
-
-
10544254257
-
Placebo-controlled trial of gabapentin in patients with amyotrophic lateral sclerosis
-
Miller RG, Moore D, Young LA, Armon C, Barohn RJ, Bromberg MB, Bryan WW, Gelinas DF, Mendoza MC, Neville HE, Parry GJ, Petajan JH, Ravits JM, Ringel SP, Ross MA, Quien A, Murphy J, Brinkman J, Burns D, Parsons J, Braiman J, Kelkar P, Hartsock L, Heffner M, Moses D. Placebo-controlled trial of gabapentin in patients with amyotrophic lateral sclerosis. Neurology 1996;47:1383-1388.
-
(1996)
Neurology
, vol.47
, pp. 1383-1388
-
-
Miller, R.G.1
Moore, D.2
Young, L.A.3
Armon, C.4
Barohn, R.J.5
Bromberg, M.B.6
Bryan, W.W.7
Gelinas, D.F.8
Mendoza, M.C.9
Neville, H.E.10
Parry, G.J.11
Petajan, J.H.12
Ravits, J.M.13
Ringel, S.P.14
Ross, M.A.15
Quien, A.16
Murphy, J.17
Brinkman, J.18
Burns, D.19
Parsons, J.20
Braiman, J.21
Kelkar, P.22
Hartsock, L.23
Heffner, M.24
Moses, D.25
more..
-
85
-
-
0032908774
-
Amyotrophic lateral sclerosis associated with mutations in superoxide dismutase: A putative mechanism of degeneration
-
Morrison BM, Morrison JH. Amyotrophic lateral sclerosis associated with mutations in superoxide dismutase: a putative mechanism of degeneration. Brain Res Rev 1999;29:121-135.
-
(1999)
Brain Res Rev
, vol.29
, pp. 121-135
-
-
Morrison, B.M.1
Morrison, J.H.2
-
87
-
-
8944256866
-
Enterovirus infection of the central nervous system of humans - Lack of association with chronic neurological disease
-
Muir P, Nicholson F, Spencer GT, Ajetynmobi JF, Starkey WG, Khan M, Archard LC, Cairns NJ, Anderson VER, Leigh PN, Howard RS, Banatvala JE. Enterovirus infection of the central nervous system of humans - lack of association with chronic neurological disease. J Gen Virol 1996;77:1469-1476.
-
(1996)
J Gen Virol
, vol.77
, pp. 1469-1476
-
-
Muir, P.1
Nicholson, F.2
Spencer, G.T.3
Ajetynmobi, J.F.4
Starkey, W.G.5
Khan, M.6
Archard, L.C.7
Cairns, N.J.8
Anderson, V.E.R.9
Leigh, P.N.10
Howard, R.S.11
Banatvala, J.E.12
-
88
-
-
0034612175
-
Inflammation and Alzheimer's disease
-
Neuroinflammation Working Group. Inflammation and Alzheimer's disease. Neurobiol Aging 2000;21:383-421.
-
(2000)
Neurobiol Aging
, vol.21
, pp. 383-421
-
-
-
90
-
-
0032896588
-
Cyclooxygenase-2: Molecular biology, pharmacology and neurobiology
-
O'Banion MK. Cyclooxygenase-2: molecular biology, pharmacology and neurobiology. Crit Rev Neurobiol 1999;13:45-82.
-
(1999)
Crit Rev Neurobiol
, vol.13
, pp. 45-82
-
-
O'Banion, M.K.1
-
91
-
-
0033989243
-
Amyotrophic lateral sclerosis: Copper/zinc superoxide dismutase (SOD1) gene mutations
-
Orrell RW. Amyotrophic lateral sclerosis: copper/zinc superoxide dismutase (SOD1) gene mutations. Neuromuscul Dis 2000;10:63-68.
-
(2000)
Neuromuscul Dis
, vol.10
, pp. 63-68
-
-
Orrell, R.W.1
-
92
-
-
0030945491
-
Clinical and functional investigation of 10 missense mutations and a novel frameshift insertion mutation of the gene for copper-zinc superoxide dismutase in UK families with amyotrophic lateral sclerosis
-
Orrell RW, Habgood JJ, Gardiner I, King AW, Bowe FA, Hallewell RA, Marklund SL, Greenwood J, Lane RJM, Debelleroche J. Clinical and functional investigation of 10 missense mutations and a novel frameshift insertion mutation of the gene for copper-zinc superoxide dismutase in UK families with amyotrophic lateral sclerosis. Neurology 1997;48:746-751.
-
(1997)
Neurology
, vol.48
, pp. 746-751
-
-
Orrell, R.W.1
Habgood, J.J.2
Gardiner, I.3
King, A.W.4
Bowe, F.A.5
Hallewell, R.A.6
Marklund, S.L.7
Greenwood, J.8
Lane, R.J.M.9
Debelleroche, J.10
-
93
-
-
85086348708
-
Detection and cellular localization of enterovirus RNA sequence in spinal cord of patients with ALS
-
Pamphlett R. Detection and cellular localization of enterovirus RNA sequence in spinal cord of patients with ALS. Neurology 2000;55:1420-1421.
-
(2000)
Neurology
, vol.55
, pp. 1420-1421
-
-
Pamphlett, R.1
-
94
-
-
0034610328
-
Caspase-1 and -3 are sequentially activated in motor neuron death in Cu/Zn superoxide dismutase-mediated familial amyotrophic lateral sclerosis
-
Pasinelli P, Houseweart MK, Brown RH, Cleveland DW. Caspase-1 and -3 are sequentially activated in motor neuron death in Cu/Zn superoxide dismutase-mediated familial amyotrophic lateral sclerosis. Proc Natl Acad Sci U S A 2000;97:13901-13906.
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 13901-13906
-
-
Pasinelli, P.1
Houseweart, M.K.2
Brown, R.H.3
Cleveland, D.W.4
-
95
-
-
0031768026
-
Protein modification by the lipid peroxidation product 4-hydroxynonenal in the spinal cords of amyotrophic lateral sclerosis
-
Pedersen WA, Fu W, Keller JN, Markesbery WR, Appel S, Smith RG, Kasarskis E, Mattson MP. Protein modification by the lipid peroxidation product 4-hydroxynonenal in the spinal cords of amyotrophic lateral sclerosis. Ann Neurol 1998;44:8819-8824.
-
(1998)
Ann Neurol
, vol.44
, pp. 8819-8824
-
-
Pedersen, W.A.1
Fu, W.2
Keller, J.N.3
Markesbery, W.R.4
Appel, S.5
Smith, R.G.6
Kasarskis, E.7
Mattson, M.P.8
-
96
-
-
0002913749
-
Microglia and the process of phagocytosis in gliomas
-
Penfield W. Microglia and the process of phagocytosis in gliomas. Am J Pathol 1925;1:77-89.
-
(1925)
Am J Pathol
, vol.1
, pp. 77-89
-
-
Penfield, W.1
-
99
-
-
0030032259
-
Brain superoxide dismutase, catalase and glutathione peroxidase activities in amyotrophic lateral sclerosis
-
Przedborski S, Donaldson D, Jakowee M, Kish SJ, Guttman M, Rosoklija G, Hays AP. Brain superoxide dismutase, catalase and glutathione peroxidase activities in amyotrophic lateral sclerosis. Ann Neurol 1996;39:158-165.
-
(1996)
Ann Neurol
, vol.39
, pp. 158-165
-
-
Przedborski, S.1
Donaldson, D.2
Jakowee, M.3
Kish, S.J.4
Guttman, M.5
Rosoklija, G.6
Hays, A.P.7
-
101
-
-
0031944832
-
An analysis of extended survival in patients with amyotrophic lateral sclerosis treated with riluzole
-
Riviere M, Meininger V, Zeisser P, Munsat T. An analysis of extended survival in patients with amyotrophic lateral sclerosis treated with riluzole. Arch Neurol 1998;55:526-528.
-
(1998)
Arch Neurol
, vol.55
, pp. 526-528
-
-
Riviere, M.1
Meininger, V.2
Zeisser, P.3
Munsat, T.4
-
102
-
-
0027401203
-
Mutations in CuZn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis
-
Rosen DR, Siddique T, Patterson D, Figlewicz DA, Sapp P, Hentati A, Donaldson S, Goto J, O'Regan JP, Deng HX. Mutations in CuZn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis. Nature 1993;362:59-62.
-
(1993)
Nature
, vol.362
, pp. 59-62
-
-
Rosen, D.R.1
Siddique, T.2
Patterson, D.3
Figlewicz, D.A.4
Sapp, P.5
Hentati, A.6
Donaldson, S.7
Goto, J.8
O'Regan, J.P.9
Deng, H.X.10
-
103
-
-
0029975105
-
Absence of serological evidence for foamy virus infection in patients with amyotrophic lateral sclerosis
-
Rosener M, Hahn H, Kranz M, Heeney J, Rethwilm A. Absence of serological evidence for foamy virus infection in patients with amyotrophic lateral sclerosis. J Med Virol 1996;48:222-226.
-
(1996)
J Med Virol
, vol.48
, pp. 222-226
-
-
Rosener, M.1
Hahn, H.2
Kranz, M.3
Heeney, J.4
Rethwilm, A.5
-
104
-
-
0029434244
-
Amyotrophic lateral sclerosis and viruses
-
Salazargrueso EF, Roos RP. Amyotrophic lateral sclerosis and viruses. Clin Neurosci 1996;3:360-367.
-
(1996)
Clin Neurosci
, vol.3
, pp. 360-367
-
-
Salazargrueso, E.F.1
Roos, R.P.2
-
105
-
-
0034836440
-
Inducible nitric oxide synthase (iNOS) and nitrotyrosine immunoreactivity in the spinal cords of transgenic mice with a G93A mutant SOD1 gene
-
Sasaki S, Warita H, Abe K, Iwata M. Inducible nitric oxide synthase (iNOS) and nitrotyrosine immunoreactivity in the spinal cords of transgenic mice with a G93A mutant SOD1 gene. J Neuropathol Exp Neurol 2001;60:839-846.
-
(2001)
J Neuropathol Exp Neurol
, vol.60
, pp. 839-846
-
-
Sasaki, S.1
Warita, H.2
Abe, K.3
Iwata, M.4
-
106
-
-
0029812020
-
Reactive astrogliosis of the spinal cord in amyotrophic lateral sclerosis
-
Schiffer D, Cordera S, Cavalla P, Migheli A. Reactive astrogliosis of the spinal cord in amyotrophic lateral sclerosis. J Neurol Sci 1996;139:27-33.
-
(1996)
J Neurol Sci
, vol.139
, pp. 27-33
-
-
Schiffer, D.1
Cordera, S.2
Cavalla, P.3
Migheli, A.4
-
107
-
-
0032485033
-
Cerebrospinal fluid interleukin 6 in amyotrophic lateral sclerosis: Immunological parameter and comparison with inflammatory and non-inflammatory central nervous system diseases
-
Sekizawa T, Openshaw H, Ohbo K, Sugamura K, Itoyama Y, Niland JC. Cerebrospinal fluid interleukin 6 in amyotrophic lateral sclerosis: immunological parameter and comparison with inflammatory and non-inflammatory central nervous system diseases. J Neurol Sci 1998;154:194-199.
-
(1998)
J Neurol Sci
, vol.154
, pp. 194-199
-
-
Sekizawa, T.1
Openshaw, H.2
Ohbo, K.3
Sugamura, K.4
Itoyama, Y.5
Niland, J.C.6
-
108
-
-
0031936175
-
Mutations in all five exons of SOD-1 may cause ALS
-
Shaw CE, Enayat ZE, Chioza BA, Alchalabi A, Radunovic A, Powell JF, Leigh PN. Mutations in all five exons of SOD-1 may cause ALS. Ann Neurol 1998;43:390-394.
-
(1998)
Ann Neurol
, vol.43
, pp. 390-394
-
-
Shaw, C.E.1
Enayat, Z.E.2
Chioza, B.A.3
Alchalabi, A.4
Radunovic, A.5
Powell, J.F.6
Leigh, P.N.7
-
109
-
-
0035955478
-
Morphological evidence for lipid peroxidation and protein glycoxidation in spinal cords from sporadic amyotrophic lateral sclerosis patients
-
Shibata N, Nagai R, Uchida K, Horiuchi S, Yamada S, Hirano A, Kawaguchi M, Yamamoto T, Saski S, Kobayashi M. Morphological evidence for lipid peroxidation and protein glycoxidation in spinal cords from sporadic amyotrophic lateral sclerosis patients. Brain Res 2001;917:97-104.
-
(2001)
Brain Res
, vol.917
, pp. 97-104
-
-
Shibata, N.1
Nagai, R.2
Uchida, K.3
Horiuchi, S.4
Yamada, S.5
Hirano, A.6
Kawaguchi, M.7
Yamamoto, T.8
Saski, S.9
Kobayashi, M.10
-
111
-
-
0030479496
-
Prostaglandin endoperoxide H synthases (cyclooxygenases) -1 and -2
-
Smith WL, Garavito RM, DeWitt DL. Prostaglandin endoperoxide H synthases (cyclooxygenases) -1 and -2. J Biol Chem 1996;271:33157-33160.
-
(1996)
J Biol Chem
, vol.271
, pp. 33157-33160
-
-
Smith, W.L.1
Garavito, R.M.2
DeWitt, D.L.3
-
112
-
-
0029782778
-
Human herpes virus 6 (HHV-6) in amyotrophic lateral sclerosis - A polymerase chain reaction (PCR) study
-
Sola P, Merelli E, Levani M, Giovannetti R, Barozzi P. Human herpes virus 6 (HHV-6) in amyotrophic lateral sclerosis - a polymerase chain reaction (PCR) study. Eur J Neurol 1996;3:315-318.
-
(1996)
Eur J Neurol
, vol.3
, pp. 315-318
-
-
Sola, P.1
Merelli, E.2
Levani, M.3
Giovannetti, R.4
Barozzi, P.5
-
113
-
-
0032588897
-
Cytosolic phospholipase A(2) is induced in reactive glia following different forms of neurodegeneration
-
Stephenson D, Rash K, Smalstig B, Roberts E, Johnstone E, Sharp J, Panetta J, Little S, Kramer R, Clemens J. Cytosolic phospholipase A(2) is induced in reactive glia following different forms of neurodegeneration. Glia 1999;27:110-128.
-
(1999)
Glia
, vol.27
, pp. 110-128
-
-
Stephenson, D.1
Rash, K.2
Smalstig, B.3
Roberts, E.4
Johnstone, E.5
Sharp, J.6
Panetta, J.7
Little, S.8
Kramer, R.9
Clemens, J.10
-
114
-
-
0028811503
-
Search for persistent infection with poliovirus or other enteroviruses in amyotrophic lateral sclerosis-motor neurone disease
-
Swanson NR, Fox SA, Mastaglia FL. Search for persistent infection with poliovirus or other enteroviruses in amyotrophic lateral sclerosis-motor neurone disease. Neuromuscul Dis 1995;5:457-465.
-
(1995)
Neuromuscul Dis
, vol.5
, pp. 457-465
-
-
Swanson, N.R.1
Fox, S.A.2
Mastaglia, F.L.3
-
115
-
-
0027972434
-
Immunosuppressive treatment of motor neuron syndrome. Attempts to distinguish a treatable disorder
-
Tan E, Lynn DJ, Amato AA, Kissel JT, Rammohan KW, Sahenk Z, Warmolts JR, Jackson CE, Barohn RJ, Mendell JR. Immunosuppressive treatment of motor neuron syndrome. Attempts to distinguish a treatable disorder. Arch Neurol 1994;51:194-200.
-
(1994)
Arch Neurol
, vol.51
, pp. 194-200
-
-
Tan, E.1
Lynn, D.J.2
Amato, A.A.3
Kissel, J.T.4
Rammohan, K.W.5
Sahenk, Z.6
Warmolts, J.R.7
Jackson, C.E.8
Barohn, R.J.9
Mendell, J.R.10
-
116
-
-
0025185079
-
Immunohistochemical characteristics of the inflammatory infiltration in amyotrophic lateral sclerosis
-
Troost D, Van den Oord JJ, Vianney de Jong JMB. Immunohistochemical characteristics of the inflammatory infiltration in amyotrophic lateral sclerosis. Neuropathol Appl Neurobiol 1990;16:401-410.
-
(1990)
Neuropathol Appl Neurobiol
, vol.16
, pp. 401-410
-
-
Troost, D.1
Van den Oord, J.J.2
Vianney de Jong, J.M.B.3
-
117
-
-
0028178503
-
Increased concentration of C4d complement protein in CSF in amyotrophic lateral sclerosis
-
Tsuboi Y, Yamada T. Increased concentration of C4d complement protein in CSF in amyotrophic lateral sclerosis. J Neurol Neurosurg Psychiatry 1994;57:859-861.
-
(1994)
J Neurol Neurosurg Psychiatry
, vol.57
, pp. 859-861
-
-
Tsuboi, Y.1
Yamada, T.2
-
118
-
-
0020050796
-
Current view on the mononuclear phagocyte system
-
Van Furth R. Current view on the mononuclear phagocyte system. Immunobiology 1982;161:178-185.
-
(1982)
Immunobiology
, vol.161
, pp. 178-185
-
-
Van Furth, R.1
-
119
-
-
0029787291
-
Survival in patients with amyotrophic lateral sclerosis treated with an array of antioxidants
-
Vyth A, Timmer JG, Bossuyt PM, Louwerse ES, de Jong JM. Survival in patients with amyotrophic lateral sclerosis treated with an array of antioxidants. J Neurol Sci 1996;139(Suppl):99-103.
-
(1996)
J Neurol Sci
, vol.139
, Issue.SUPPL.
, pp. 99-103
-
-
Vyth, A.1
Timmer, J.G.2
Bossuyt, P.M.3
Louwerse, E.S.4
De Jong, J.M.5
-
120
-
-
0025072761
-
Immunosuppressive treatment of patients with amyotrophic lateral sclerosis
-
Werdelin L, Boysen G, Jensen TS, Mogensen P. Immunosuppressive treatment of patients with amyotrophic lateral sclerosis. Acta Neurol Scand 1990;82:132-134.
-
(1990)
Acta Neurol Scand
, vol.82
, pp. 132-134
-
-
Werdelin, L.1
Boysen, G.2
Jensen, T.S.3
Mogensen, P.4
-
121
-
-
0028176068
-
Sequences specific for enterovirus detected in spinal cord from patients with motor neurone disease
-
Woodall CJ, Riding MH, Graham DI, Clements GB. Sequences specific for enterovirus detected in spinal cord from patients with motor neurone disease. BMJ 1994;308:1541-1543.
-
(1994)
BMJ
, vol.308
, pp. 1541-1543
-
-
Woodall, C.J.1
Riding, M.H.2
Graham, D.I.3
Clements, G.B.4
-
122
-
-
0034785509
-
The gene encoding alsin, a protein with three guanine-nucleotide exchange factor domains, is mutated in a form of recessive amyotrophic lateral sclerosis
-
Yang Y, Hentati A, Deng H-X, Dabbagh O, Saski T, Hirano M, Hung W-Y, Ouahchi K, Yan J, Azim AC, Cole N, Gascon G, Yagmour A, Ben-Humida M, Pericak-Vance M, Hentati F, Siddique T. The gene encoding alsin, a protein with three guanine-nucleotide exchange factor domains, is mutated in a form of recessive amyotrophic lateral sclerosis. Nat Genet 2001;29:160-165.
-
(2001)
Nat Genet
, vol.29
, pp. 160-165
-
-
Yang, Y.1
Hentati, A.2
Deng, H.-X.3
Dabbagh, O.4
Saski, T.5
Hirano, M.6
Hung, W.-Y.7
Ouahchi, K.8
Yan, J.9
Azim, A.C.10
Cole, N.11
Gascon, G.12
Yagmour, A.13
Ben-Humida, M.14
Pericak-Vance, M.15
Hentati, F.16
Siddique, T.17
-
123
-
-
0033526660
-
Distribution of cyclooxygenase-1 and cyclooxygenase-2 mRNAs and proteins in human brain and peripheral organs
-
Yasojima K, Schwab C, McGeer EG, McGeer PL. Distribution of cyclooxygenase-1 and cyclooxygenase-2 mRNAs and proteins in human brain and peripheral organs. Brain Res 1999;830:226-236.
-
(1999)
Brain Res
, vol.830
, pp. 226-236
-
-
Yasojima, K.1
Schwab, C.2
McGeer, E.G.3
McGeer, P.L.4
-
124
-
-
0035099170
-
Generation of C-reactive protein and complement components in atherosclerotic plaques
-
Yasojima K, Schwab C, McGeer EG, McGeer PL. Generation of C-reactive protein and complement components in atherosclerotic plaques. Am J Pathol 2001;158:1039-1051.
-
(2001)
Am J Pathol
, vol.158
, pp. 1039-1051
-
-
Yasojima, K.1
Schwab, C.2
McGeer, E.G.3
McGeer, P.L.4
-
125
-
-
0033061855
-
Upregulated production and activation of the complement system in Alzheimer's disease brain
-
Yasojima K, Schwab C, McGeer EG, McGeer PL. Upregulated production and activation of the complement system in Alzheimer's disease brain. Am J Pathol 1999;154:927-936.
-
(1999)
Am J Pathol
, vol.154
, pp. 927-936
-
-
Yasojima, K.1
Schwab, C.2
McGeer, E.G.3
McGeer, P.L.4
-
127
-
-
0028848472
-
Role of interferon-y in immune cell regulation
-
Young HA, Hardy KJ. Role of interferon-y in immune cell regulation. J Leukoc Biol 1995;58:373-381.
-
(1995)
J Leukoc Biol
, vol.58
, pp. 373-381
-
-
Young, H.A.1
Hardy, K.J.2
|