A seeding reaction recapitulates intracellular formation of sarkosyl-insoluble transactivation response element (TAR) DNA-binding protein-43 inclusions

Journal of Biological Chemistry

Volumn 286, Issue 21, 2011, Pages 18664-18672

  Furukawa, Yoshiaki ^a,b   Kaneko, Kumi ^a   Watanabe, Shoji ^a   Yamanaka, Koji ^a   Nukina, Nobuyuki ^a  

^a RIKEN BRAIN SCIENCE INSTITUTE   (Japan)

^b KEIO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ALS PATIENTS; AMYOTROPHIC LATERAL SCLEROSIS; CELL MODEL; CULTURED CELL; DNA-BINDING; FIBRILLAR AGGREGATES; IN-VITRO; NUCLEAR PROTEINS; PROMINENT FEATURES; TRANS-ACTIVATION RESPONSE; UBIQUITINATION;

NUCLEIC ACIDS; SEED; TAR; TISSUE;

PROTEINS;

TAR DNA BINDING PROTEIN;

AMYOTROPHIC LATERAL SCLEROSIS; ARTICLE; CELL STRAIN HEK293; CONTROLLED STUDY; HUMAN; HUMAN CELL; IN VITRO STUDY; PLASMID; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN FUNCTION; UBIQUITINATION;

AMYOTROPHIC LATERAL SCLEROSIS; DNA-BINDING PROTEINS; HEK293 CELLS; HUMANS; INTRANUCLEAR INCLUSION BODIES; MODELS, BIOLOGICAL; RESPONSE ELEMENTS; SARCOSINE; SOLUBILITY;

EID: 79956311051     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.231209     Document Type: Article

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