Ultrastructural mitochondrial abnormalities in patients with sporadic amyotrophic lateral sclerosis

Archives of Neurology

Volumn 68, Issue 12, 2011, Pages 1612-1613

  Napoli, Laura ^a   Crugnola, Veronica ^b   Lamperti, Costanza ^c   Silani, Vincenzo ^d   Di Mauro, Salvatore ^e   Bresolin, Nereo ^a   Moggio, Maurizio ^a  

^a UNIVERSITY OF MILAN   (Italy)

^b San Giuseppe Hospital   (Italy)

^c DEPARTMENT OF NEUROSURGERY   (Italy)

^d ISTITUTO AUXOLOGICO ITALIANO   (Italy)

^e NewYork Presbyterian Hospital   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AEROBIC METABOLISM; AMYOTROPHIC LATERAL SCLEROSIS; ARTICLE; CLINICAL ARTICLE; DISEASE SEVERITY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; HISTOCHEMISTRY; HUMAN; HUMAN CELL; HUMAN TISSUE; MUSCLE BIOPSY; PATHOGENESIS; PRIORITY JOURNAL; SPORADIC AMYOTROPHIC LATERAL SCLEROSIS; ULTRASTRUCTURE ANALYSIS AND ELECTRON MICROSCOPY;

EID: 83455217437     PISSN: 00039942     EISSN: 15383687     Source Type: Journal    
DOI: 10.1001/archneur.68.12.1612     Document Type: Article

References (6)

1. Bossy-Wetzel E, Barsoum MJ, Godzik A, Schwarzenbacher R, Lipton SA. Mitochondrial fission in apoptosis, neurodegeneration and aging. Curr Opin Cell Biol. 2003;15(6):706-716. (Pubitemid 37487964)
2. Chan DC. Mitochondrial dynamics in disease. N Engl J Med. 2007;356(17):1707-1709. (Pubitemid 46658702)
3. Higgins CM, Jung C, Xu Z. ALS-associated mutant SOD1G93A causes mitochondrial vacuolation by expansion of the intermembrane space and by involvement of SOD1 aggregation and peroxisomes. BMC Neurosci. 2003;4:16.
4. Comi GP, Bordoni A, Salani S, et al. Cytochrome c oxidase subunit I microdeletion in a patient with motor neuron disease. Ann Neurol. 1998;43(1):110-116. (Pubitemid 28124656)
5. Finsterer J. Mitochondriopathy mimicking amyotrophic lateral sclerosis. Neurologist. 2003;9(1):45-48. (Pubitemid 36164023)
6. Crugnola V, Lamperti C, Lucchini V, et al. Mitochondrial respiratory chain dysfunction in muscle from patients with amyotrophic lateral sclerosis. Arch Neurol. 2010;67(7):849-854.