-
1
-
-
0036212849
-
Innate immune recognition
-
doi: 10.1146/annurev.immunol.20.083001.084359
-
Janeway CA Jr, Medzhitov R. Innate immune recognition. Annu Rev Immunol (2002) 20:197-216. doi: 10.1146/annurev.immunol.20.083001.084359
-
(2002)
Annu Rev Immunol
, vol.20
, pp. 197-216
-
-
Janeway Jr, C.A.1
Medzhitov, R.2
-
2
-
-
33845951211
-
DAMPs PAMPs and alarmins: all we need to know about danger
-
doi:10.1189/jlb.0306164
-
Bianchi ME. DAMPs, PAMPs and alarmins: all we need to know about danger. J Leukoc Biol (2007) 81:1-5. doi:10.1189/jlb.0306164
-
(2007)
J Leukoc Biol
, vol.81
, pp. 1-5
-
-
Bianchi, M.E.1
-
3
-
-
79956300649
-
Toll-like receptors and their crosstalk with other innate receptors in infection and immunity
-
doi:10.1016/j.immuni.2011.05.006
-
Kawai T, Akira S. Toll-like receptors and their crosstalk with other innate receptors in infection and immunity. Immunity (2011) 34:637-50. doi:10.1016/j.immuni.2011.05.006
-
(2011)
Immunity
, vol.34
, pp. 637-650
-
-
Kawai, T.1
Akira, S.2
-
4
-
-
79958205445
-
Sensing disease and danger: a survey of vertebrate PRRs and their origins
-
doi:10.1016/j.dci.2011.01.008
-
Hansen JD, Vojtech LN, Laing KJ. Sensing disease and danger: a survey of vertebrate PRRs and their origins. Dev Comp Immunol (2011) 35:886-97. doi:10.1016/j.dci.2011.01.008
-
(2011)
Dev Comp Immunol
, vol.35
, pp. 886-897
-
-
Hansen, J.D.1
Vojtech, L.N.2
Laing, K.J.3
-
5
-
-
84867876599
-
Effector functions of NLRs in the intestine: innate sensing, cell death, and disease
-
doi:10.1007/s12026-012-8317-3
-
Yeretssian G. Effector functions of NLRs in the intestine: innate sensing, cell death, and disease. Immunol Res (2012) 54:25-36. doi:10.1007/s12026-012-8317-3
-
(2012)
Immunol Res
, vol.54
, pp. 25-36
-
-
Yeretssian, G.1
-
6
-
-
84884332722
-
Mechanisms of NOD-like receptor-associated inflammasome activation
-
doi:10.1016/j.immuni.2013.08.037
-
Wen H, Miao EA, Ting JP. Mechanisms of NOD-like receptor-associated inflammasome activation. Immunity (2013) 39:432-41. doi:10.1016/j.immuni.2013.08.037
-
(2013)
Immunity
, vol.39
, pp. 432-441
-
-
Wen, H.1
Miao, E.A.2
Ting, J.P.3
-
7
-
-
84878173821
-
Cytosolic sensing of viruses
-
doi:10.1016/j.immuni.2013.05.007
-
Goubau D, Deddouche S, Reis E, Sousa C. Cytosolic sensing of viruses. Immunity (2013) 38:855-69. doi:10.1016/j.immuni.2013.05.007
-
(2013)
Immunity
, vol.38
, pp. 855-869
-
-
Goubau, D.1
Deddouche, S.2
Reis, E.3
Sousa, C.4
-
8
-
-
84865411904
-
C-type lectin receptors orchestrate antifungal immunity
-
doi:10.1038/ni.2369
-
Hardison SE, Brown GD. C-type lectin receptors orchestrate antifungal immunity. Nat Immunol (2012) 13:817-22. doi:10.1038/ni.2369
-
(2012)
Nat Immunol
, vol.13
, pp. 817-822
-
-
Hardison, S.E.1
Brown, G.D.2
-
9
-
-
84892149853
-
An update on PYRIN domain-containing pattern recognition receptors: from immunity to pathology
-
doi:10.3389/fimmu.2013.00440
-
Ratsimandresy RA, Dorfleutner A, Stehlik C. An update on PYRIN domain-containing pattern recognition receptors: from immunity to pathology. Front Immunol (2013) 4:440. doi:10.3389/fimmu.2013.00440
-
(2013)
Front Immunol
, vol.4
, pp. 440
-
-
Ratsimandresy, R.A.1
Dorfleutner, A.2
Stehlik, C.3
-
10
-
-
84890392687
-
Beneficial and detrimental roles of NLRs in carcinogenesis
-
doi:10.3389/fimmu.2013.00370
-
Janowski AM, Kolb R, Zhang W, Sutterwala FS. Beneficial and detrimental roles of NLRs in carcinogenesis. Front Immunol (2013) 4:370. doi:10.3389/fimmu.2013.00370
-
(2013)
Front Immunol
, vol.4
, pp. 370
-
-
Janowski, A.M.1
Kolb, R.2
Zhang, W.3
Sutterwala, F.S.4
-
11
-
-
0035901090
-
Inflammation and cancer: back to Virchow?
-
doi:10.1016/S0140-6736(00)04046-0
-
Balkwill F, Mantovani A. Inflammation and cancer: back to Virchow? Lancet (2001) 357:539-45. doi:10.1016/S0140-6736(00)04046-0
-
(2001)
Lancet
, vol.357
, pp. 539-545
-
-
Balkwill, F.1
Mantovani, A.2
-
12
-
-
47949096781
-
Cancer-related inflammation
-
doi:10.1038/nature07205
-
Mantovani A, Allavena P, Sica A, Balkwill F. Cancer-related inflammation. Nature (2008) 454:436-44. doi:10.1038/nature07205
-
(2008)
Nature
, vol.454
, pp. 436-444
-
-
Mantovani, A.1
Allavena, P.2
Sica, A.3
Balkwill, F.4
-
13
-
-
77950346282
-
Immunity, inflammation, and cancer
-
doi:10.1016/j.cell.2010.01.025
-
Grivennikov SI, Greten FR, Karin M. Immunity, inflammation, and cancer. Cell (2010) 140:883-99. doi:10.1016/j.cell.2010.01.025
-
(2010)
Cell
, vol.140
, pp. 883-899
-
-
Grivennikov, S.I.1
Greten, F.R.2
Karin, M.3
-
14
-
-
67349194929
-
Infections and cancer: established associations and new hypotheses
-
doi:10.1016/j.critrevonc.2008.07.021
-
de Martel C, Franceschi S. Infections and cancer: established associations and new hypotheses. Crit Rev Oncol Hematol (2009) 70:183-94. doi:10.1016/j.critrevonc.2008.07.021
-
(2009)
Crit Rev Oncol Hematol
, vol.70
, pp. 183-194
-
-
de Martel, C.1
Franceschi, S.2
-
15
-
-
73649112422
-
Tobacco smoke promotes lung tumorigenesis by triggering IKKbeta- and JNK1-dependent inflammation
-
doi:10.1016/j.ccr.2009.12.008
-
Takahashi H, Ogata H, Nishigaki R, Broide DH, Karin M. Tobacco smoke promotes lung tumorigenesis by triggering IKKbeta- and JNK1-dependent inflammation. Cancer Cell (2010) 17:89-97. doi:10.1016/j.ccr.2009.12.008
-
(2010)
Cancer Cell
, vol.17
, pp. 89-97
-
-
Takahashi, H.1
Ogata, H.2
Nishigaki, R.3
Broide, D.H.4
Karin, M.5
-
16
-
-
62549089788
-
Inflammation and mitochondrial fatty acid beta-oxidation link obesity to early tumor promotion
-
doi:10.1073/pnas.0802864106
-
Khasawneh J, Schulz MD, Walch A, Rozman J, Hrabe De Angelis M, Klingenspor M, et al. Inflammation and mitochondrial fatty acid beta-oxidation link obesity to early tumor promotion. Proc Natl Acad Sci U S A (2009) 106:3354-9. doi:10.1073/pnas.0802864106
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 3354-3359
-
-
Khasawneh, J.1
Schulz, M.D.2
Walch, A.3
Rozman, J.4
Hrabe De Hrabe, M.5
Klingenspor, M.6
-
17
-
-
74549167737
-
Dietary and genetic obesity promote liver inflammation and tumorigenesis by enhancing IL-6 and TNF expression
-
doi:10.1016/j.cell.2009.12.052
-
Park EJ, Lee JH, Yu GY, He G, Ali SR, Holzer RG, et al. Dietary and genetic obesity promote liver inflammation and tumorigenesis by enhancing IL-6 and TNF expression. Cell (2010) 140:197-208. doi:10.1016/j.cell.2009.12.052
-
(2010)
Cell
, vol.140
, pp. 197-208
-
-
Park, E.J.1
Lee, J.H.2
Yu, G.Y.3
He, G.4
Ali, S.R.5
Holzer, R.G.6
-
18
-
-
0034051068
-
Age-associated increased interleukin-6 gene expression, late-life diseases, and frailty
-
doi:10.1146/annurev.med.51.1.245
-
Ershler WB, Keller ET. Age-associated increased interleukin-6 gene expression, late-life diseases, and frailty. Annu Rev Med (2000) 51:245-70. doi:10.1146/annurev.med.51.1.245
-
(2000)
Annu Rev Med
, vol.51
, pp. 245-270
-
-
Ershler, W.B.1
Keller, E.T.2
-
19
-
-
68249096784
-
Persistent DNA damage signalling triggers senescence-associated inflammatory cytokine secretion
-
doi:10.1038/ncb1909
-
Rodier F, Coppe JP, Patil CK, Hoeijmakers WA, Munoz DP, Raza SR, et al. Persistent DNA damage signalling triggers senescence-associated inflammatory cytokine secretion. Nat Cell Biol (2009) 11:973-9. doi:10.1038/ncb1909
-
(2009)
Nat Cell Biol
, vol.11
, pp. 973-979
-
-
Rodier, F.1
Coppe, J.P.2
Patil, C.K.3
Hoeijmakers, W.A.4
Munoz, D.P.5
Raza, S.R.6
-
20
-
-
0037180757
-
Inflammation and cancer
-
doi:10.1038/nature01322
-
Coussens LM, Werb Z. Inflammation and cancer. Nature (2002) 420:860-7. doi:10.1038/nature01322
-
(2002)
Nature
, vol.420
, pp. 860-867
-
-
Coussens, L.M.1
Werb, Z.2
-
21
-
-
84901853867
-
Cancer epigenetics: tumor heterogeneity, plasticity of stem-like states, and drug resistance
-
doi:10.1016/j.molcel.2014.05.015
-
Easwaran H, Tsai HC, Baylin SB. Cancer epigenetics: tumor heterogeneity, plasticity of stem-like states, and drug resistance. Mol Cell (2014) 54:716-27. doi:10.1016/j.molcel.2014.05.015
-
(2014)
Mol Cell
, vol.54
, pp. 716-727
-
-
Easwaran, H.1
Tsai, H.C.2
Baylin, S.B.3
-
22
-
-
79952284127
-
Hallmarks of cancer: the next generation
-
doi:10.1016/j.cell.2011.02.013
-
Hanahan D, Weinberg RA. Hallmarks of cancer: the next generation. Cell (2011) 144:646-74. doi:10.1016/j.cell.2011.02.013
-
(2011)
Cell
, vol.144
, pp. 646-674
-
-
Hanahan, D.1
Weinberg, R.A.2
-
23
-
-
84860389354
-
Deciphering the rules of programmed cell death to improve therapy of cancer and other diseases
-
doi:10.1038/emboj.2011.307
-
Strasser A, Cory S, Adams JM. Deciphering the rules of programmed cell death to improve therapy of cancer and other diseases. EMBO J (2011) 30:3667-83. doi:10.1038/emboj.2011.307
-
(2011)
EMBO J
, vol.30
, pp. 3667-3683
-
-
Strasser, A.1
Cory, S.2
Adams, J.M.3
-
24
-
-
84906938621
-
Small-molecule SMAC mimetics as new cancer therapeutics
-
doi:10.1016/j.pharmthera.2014.05.007
-
Bai L, Smith DC, Wang S. Small-molecule SMAC mimetics as new cancer therapeutics. Pharmacol Ther (2014). doi:10.1016/j.pharmthera.2014.05.007
-
(2014)
Pharmacol Ther
-
-
Bai, L.1
Smith, D.C.2
Wang, S.3
-
25
-
-
0035920126
-
X-linked inhibitor of apoptosis protein (XIAP) inhibits caspase-3 and -7 in distinct modes
-
doi:10.1074/jbc.M102415200
-
Suzuki Y, Nakabayashi Y, Nakata K, Reed JC, Takahashi R. X-linked inhibitor of apoptosis protein (XIAP) inhibits caspase-3 and -7 in distinct modes. J Biol Chem (2001) 276:27058-63. doi:10.1074/jbc.M102415200
-
(2001)
J Biol Chem
, vol.276
, pp. 27058-27063
-
-
Suzuki, Y.1
Nakabayashi, Y.2
Nakata, K.3
Reed, J.C.4
Takahashi, R.5
-
26
-
-
68949210567
-
Anti-apoptotic genes in the survival of monocytic cells during infection
-
doi:10.2174/138920209788920967
-
Busca A, Saxena M, Kryworuchko M, Kumar A. Anti-apoptotic genes in the survival of monocytic cells during infection. Curr Genomics (2009) 10:306-17. doi:10.2174/138920209788920967
-
(2009)
Curr Genomics
, vol.10
, pp. 306-317
-
-
Busca, A.1
Saxena, M.2
Kryworuchko, M.3
Kumar, A.4
-
27
-
-
77954930632
-
IAPs: from caspase inhibitors to modulators of NF-kappaB, inflammation and cancer
-
doi:10.1038/nrc2889
-
Gyrd-Hansen M, Meier P. IAPs: from caspase inhibitors to modulators of NF-kappaB, inflammation and cancer. Nat Rev Cancer (2010) 10:561-74. doi:10.1038/nrc2889
-
(2010)
Nat Rev Cancer
, vol.10
, pp. 561-574
-
-
Gyrd-Hansen, M.1
Meier, P.2
-
28
-
-
82755190057
-
CpG protects human monocytic cells against HIV-Vpr-induced apoptosis by cellular inhibitor of apoptosis-2 through the calcium-activated JNK pathway in a TLR9-independent manner
-
doi:10.4049/jimmunol.1100115
-
Saxena M, Busca A, Pandey S, Kryworuchko M, Kumar A. CpG protects human monocytic cells against HIV-Vpr-induced apoptosis by cellular inhibitor of apoptosis-2 through the calcium-activated JNK pathway in a TLR9-independent manner. J Immunol (2011) 187:5865-78. doi:10.4049/jimmunol.1100115
-
(2011)
J Immunol
, vol.187
, pp. 5865-5878
-
-
Saxena, M.1
Busca, A.2
Pandey, S.3
Kryworuchko, M.4
Kumar, A.5
-
29
-
-
84860369516
-
Critical role for antiapoptotic Bcl-xL and Mcl-1 in human macrophage survival and cellular IAP1/2 (cIAP1/2) in resistance to HIV-Vpr-induced apoptosis
-
doi:10.1074/jbc.M111.312660
-
Busca A, Saxena M, Kumar A. Critical role for antiapoptotic Bcl-xL and Mcl-1 in human macrophage survival and cellular IAP1/2 (cIAP1/2) in resistance to HIV-Vpr-induced apoptosis. J Biol Chem (2012) 287:15118-33. doi:10.1074/jbc.M111.312660
-
(2012)
J Biol Chem
, vol.287
, pp. 15118-15133
-
-
Busca, A.1
Saxena, M.2
Kumar, A.3
-
30
-
-
37549048249
-
The BCL-2 protein family: opposing activities that mediate cell death
-
doi:10.1038/nrm2308
-
Youle RJ, Strasser A. The BCL-2 protein family: opposing activities that mediate cell death. Nat Rev Mol Cell Biol (2008) 9:47-59. doi:10.1038/nrm2308
-
(2008)
Nat Rev Mol Cell Biol
, vol.9
, pp. 47-59
-
-
Youle, R.J.1
Strasser, A.2
-
31
-
-
80051761743
-
The role of Bcl-2 and its pro-survival relatives in tumourigenesis and cancer therapy
-
doi:10.1038/cdd.2011.17
-
Kelly PN, Strasser A. The role of Bcl-2 and its pro-survival relatives in tumourigenesis and cancer therapy. Cell Death Differ (2011) 18:1414-24. doi:10.1038/cdd.2011.17
-
(2011)
Cell Death Differ
, vol.18
, pp. 1414-1424
-
-
Kelly, P.N.1
Strasser, A.2
-
32
-
-
85006263913
-
BID regulation by p53 contributes to chemosensitivity
-
doi:10.1038/ncb866
-
Sax JK, Fei P, Murphy ME, Bernhard E, Korsmeyer SJ, El-Deiry WS. BID regulation by p53 contributes to chemosensitivity. Nat Cell Biol (2002) 4:842-9. doi:10.1038/ncb866
-
(2002)
Nat Cell Biol
, vol.4
, pp. 842-849
-
-
Sax, J.K.1
Fei, P.2
Murphy, M.E.3
Bernhard, E.4
Korsmeyer, S.J.5
El-Deiry, W.S.6
-
33
-
-
67349129712
-
Puma and to a lesser extent Noxa are suppressors of Myc-induced lymphomagenesis
-
doi:10.1038/cdd.2008.195
-
Michalak EM, Jansen ES, Happo L, Cragg MS, Tai L, Smyth GK, et al. Puma and to a lesser extent Noxa are suppressors of Myc-induced lymphomagenesis. Cell Death Differ (2009) 16:684-96. doi:10.1038/cdd.2008.195
-
(2009)
Cell Death Differ
, vol.16
, pp. 684-696
-
-
Michalak, E.M.1
Jansen, E.S.2
Happo, L.3
Cragg, M.S.4
Tai, L.5
Smyth, G.K.6
-
34
-
-
0026561121
-
Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours
-
doi:10.1038/356215a0
-
Donehower LA, Harvey M, Slagle BL, Mcarthur MJ, Montgomery CA Jr, Butel JS, et al. Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours. Nature (1992) 356:215-21. doi:10.1038/356215a0
-
(1992)
Nature
, vol.356
, pp. 215-221
-
-
Donehower, L.A.1
Harvey, M.2
Slagle, B.L.3
Mcarthur, M.J.4
Montgomery Jr, C.A.5
Butel, J.S.6
-
35
-
-
77955363995
-
TP53 mutations in human cancers: origins, consequences, and clinical use
-
doi:10.1101/cshperspect.a001008
-
Olivier M, Hollstein M, Hainaut P. TP53 mutations in human cancers: origins, consequences, and clinical use. Cold Spring Harb Perspect Biol (2010) 2:a001008. doi:10.1101/cshperspect.a001008
-
(2010)
Cold Spring Harb Perspect Biol
, vol.2
-
-
Olivier, M.1
Hollstein, M.2
Hainaut, P.3
-
36
-
-
84899622427
-
Unravelling mechanisms of p53-mediated tumour suppression
-
doi:10.1038/nrc3711
-
Bieging KT, Mello SS, Attardi LD. Unravelling mechanisms of p53-mediated tumour suppression. Nat Rev Cancer (2014) 14:359-70. doi:10.1038/nrc3711
-
(2014)
Nat Rev Cancer
, vol.14
, pp. 359-370
-
-
Bieging, K.T.1
Mello, S.S.2
Attardi, L.D.3
-
37
-
-
84898608231
-
Understanding the non-canonical pathways involved in p53-mediated tumor suppression
-
doi:10.1093/carcin/bgt487
-
Hager KM, Gu W. Understanding the non-canonical pathways involved in p53-mediated tumor suppression. Carcinogenesis (2014) 35:740-6. doi:10.1093/carcin/bgt487
-
(2014)
Carcinogenesis
, vol.35
, pp. 740-746
-
-
Hager, K.M.1
Gu, W.2
-
38
-
-
84897944609
-
Cancer-induced alterations of NK-mediated target recognition: current and investigational pharmacological strategies aiming at restoring NK-mediated anti-tumor activity
-
doi:10.3389/fimmu.2014.00122
-
Chretien AS, Le Roy A, Vey N, Prebet T, Blaise D, Fauriat C, et al. Cancer-induced alterations of NK-mediated target recognition: current and investigational pharmacological strategies aiming at restoring NK-mediated anti-tumor activity. Front Immunol (2014) 5:122. doi:10.3389/fimmu.2014.00122
-
(2014)
Front Immunol
, vol.5
, pp. 122
-
-
Chretien, A.S.1
Le Roy, A.2
Vey, N.3
Prebet, T.4
Blaise, D.5
Fauriat, C.6
-
39
-
-
84858784892
-
Targeting natural killer cells and natural killer T cells in cancer
-
doi:10.1038/nri3174
-
Vivier E, Ugolini S, Blaise D, Chabannon C, Brossay L. Targeting natural killer cells and natural killer T cells in cancer. Nat Rev Immunol (2012) 12:239-52. doi:10.1038/nri3174
-
(2012)
Nat Rev Immunol
, vol.12
, pp. 239-252
-
-
Vivier, E.1
Ugolini, S.2
Blaise, D.3
Chabannon, C.4
Brossay, L.5
-
40
-
-
0033532091
-
Human CARD4 protein is a novel CED-4/Apaf-1 cell death family member that activates NF-kappaB
-
doi:10.1074/jbc.274.19.12955
-
Bertin J, Nir WJ, Fischer CM, Tayber OV, Errada PR, Grant JR, et al. Human CARD4 protein is a novel CED-4/Apaf-1 cell death family member that activates NF-kappaB. J Biol Chem (1999) 274:12955-8. doi:10.1074/jbc.274.19.12955
-
(1999)
J Biol Chem
, vol.274
, pp. 12955-12958
-
-
Bertin, J.1
Nir, W.J.2
Fischer, C.M.3
Tayber, O.V.4
Errada, P.R.5
Grant, J.R.6
-
41
-
-
0033591330
-
Nod1, an Apaf-1-like activator of caspase-9 and nuclear factor-kappaB
-
doi:10.1074/jbc.274.21.14560
-
Inohara N, Koseki T, Del Peso L, Hu Y, Yee C, Chen S, et al. Nod1, an Apaf-1-like activator of caspase-9 and nuclear factor-kappaB. J Biol Chem (1999) 274:14560-7. doi:10.1074/jbc.274.21.14560
-
(1999)
J Biol Chem
, vol.274
, pp. 14560-14567
-
-
Inohara, N.1
Koseki, T.2
Del Peso, L.3
Hu, Y.4
Yee, C.5
Chen, S.6
-
42
-
-
0035895992
-
Nod2, a Nod1/Apaf-1 family member that is restricted to monocytes and activates NF-kappaB
-
doi:10.1074/jbc.M008072200
-
Ogura Y, Inohara N, Benito A, Chen FF, Yamaoka S, Nunez G. Nod2, a Nod1/Apaf-1 family member that is restricted to monocytes and activates NF-kappaB. J Biol Chem (2001) 276:4812-8. doi:10.1074/jbc.M008072200
-
(2001)
J Biol Chem
, vol.276
, pp. 4812-4818
-
-
Ogura, Y.1
Inohara, N.2
Benito, A.3
Chen, F.F.4
Yamaoka, S.5
Nunez, G.6
-
43
-
-
40449140937
-
The NLR gene family: a standard nomenclature
-
doi:10.1016/j.immuni.2008.02.005
-
Ting JP, Lovering RC, Alnemri ES, Bertin J, Boss JM, Davis BK, et al. The NLR gene family: a standard nomenclature. Immunity (2008) 28:285-7. doi:10.1016/j.immuni.2008.02.005
-
(2008)
Immunity
, vol.28
, pp. 285-287
-
-
Ting, J.P.1
Lovering, R.C.2
Alnemri, E.S.3
Bertin, J.4
Boss, J.M.5
Davis, B.K.6
-
44
-
-
0035379670
-
Dendritic cell-specific MHC class II transactivator contains a caspase recruitment domain that confers potent transactivation activity
-
doi:10.1074/jbc.M101295200
-
Nickerson K, Sisk TJ, Inohara N, Yee CS, Kennell J, Cho MC, et al. Dendritic cell-specific MHC class II transactivator contains a caspase recruitment domain that confers potent transactivation activity. J Biol Chem (2001) 276:19089-93. doi:10.1074/jbc.M101295200
-
(2001)
J Biol Chem
, vol.276
, pp. 19089-19093
-
-
Nickerson, K.1
Sisk, T.J.2
Inohara, N.3
Yee, C.S.4
Kennell, J.5
Cho, M.C.6
-
45
-
-
0037228017
-
Birc1e is the gene within the Lgn1 locus associated with resistance to Legionella pneumophila
-
doi:10.1038/ng1065
-
Diez E, Lee SH, Gauthier S, Yaraghi Z, Tremblay M, Vidal S, et al. Birc1e is the gene within the Lgn1 locus associated with resistance to Legionella pneumophila. Nat Genet (2003) 33:55-60. doi:10.1038/ng1065
-
(2003)
Nat Genet
, vol.33
, pp. 55-60
-
-
Diez, E.1
Lee, S.H.2
Gauthier, S.3
Yaraghi, Z.4
Tremblay, M.5
Vidal, S.6
-
46
-
-
0037425584
-
Naip5 affects host susceptibility to the intracellular pathogen Legionella pneumophila
-
doi:10.1016/S0960-9822(02)01359-3
-
Wright EK, Goodart SA, Growney JD, Hadinoto V, Endrizzi MG, Long EM, et al. Naip5 affects host susceptibility to the intracellular pathogen Legionella pneumophila. Curr Biol (2003) 13:27-36. doi:10.1016/S0960-9822(02)01359-3
-
(2003)
Curr Biol
, vol.13
, pp. 27-36
-
-
Wright, E.K.1
Goodart, S.A.2
Growney, J.D.3
Hadinoto, V.4
Endrizzi, M.G.5
Long, E.M.6
-
47
-
-
52549099416
-
Critical function for Naip5 in inflammasome activation by a conserved carboxy-terminal domain of flagellin
-
doi:10.1038/ni.1646
-
Lightfield KL, Persson J, Brubaker SW, Witte CE, Von Moltke J, Dunipace EA, et al. Critical function for Naip5 in inflammasome activation by a conserved carboxy-terminal domain of flagellin. Nat Immunol (2008) 9:1171-8. doi:10.1038/ni.1646
-
(2008)
Nat Immunol
, vol.9
, pp. 1171-1178
-
-
Lightfield, K.L.1
Persson, J.2
Brubaker, S.W.3
Witte, C.E.4
Von Moltke, J.5
Dunipace, E.A.6
-
48
-
-
84893702846
-
NOD proteins: regulators of inflammation in health and disease
-
doi:10.1038/nri3565
-
Philpott DJ, Sorbara MT, Robertson SJ, Croitoru K, Girardin SE. NOD proteins: regulators of inflammation in health and disease. Nat Rev Immunol (2014) 14:9-23. doi:10.1038/nri3565
-
(2014)
Nat Rev Immunol
, vol.14
, pp. 9-23
-
-
Philpott, D.J.1
Sorbara, M.T.2
Robertson, S.J.3
Croitoru, K.4
Girardin, S.E.5
-
49
-
-
0035978651
-
Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease
-
doi:10.1038/35079107
-
Hugot JP, Chamaillard M, Zouali H, Lesage S, Cezard JP, Belaiche J, et al. Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease. Nature (2001) 411:599-603. doi:10.1038/35079107
-
(2001)
Nature
, vol.411
, pp. 599-603
-
-
Hugot, J.P.1
Chamaillard, M.2
Zouali, H.3
Lesage, S.4
Cezard, J.P.5
Belaiche, J.6
-
50
-
-
0035978533
-
A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease
-
doi:10.1038/35079114
-
Ogura Y, Bonen DK, Inohara N, Nicolae DL, Chen FF, Ramos R, et al. A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease. Nature (2001) 411:603-6. doi:10.1038/35079114
-
(2001)
Nature
, vol.411
, pp. 603-606
-
-
Ogura, Y.1
Bonen, D.K.2
Inohara, N.3
Nicolae, D.L.4
Chen, F.F.5
Ramos, R.6
-
51
-
-
0036671894
-
The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta
-
doi:10.1016/S1097-2765(02)00599-3
-
Martinon F, Burns K, Tschopp J. The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta. Mol Cell (2002) 10:417-26. doi:10.1016/S1097-2765(02)00599-3
-
(2002)
Mol Cell
, vol.10
, pp. 417-426
-
-
Martinon, F.1
Burns, K.2
Tschopp, J.3
-
52
-
-
38749097018
-
NLRX1 is a regulator of mitochondrial antiviral immunity
-
doi:10.1038/nature06501
-
Moore CB, Bergstralh DT, Duncan JA, Lei Y, Morrison TE, Zimmermann AG, et al. NLRX1 is a regulator of mitochondrial antiviral immunity. Nature (2008) 451:573-7. doi:10.1038/nature06501
-
(2008)
Nature
, vol.451
, pp. 573-577
-
-
Moore, C.B.1
Bergstralh, D.T.2
Duncan, J.A.3
Lei, Y.4
Morrison, T.E.5
Zimmermann, A.G.6
-
53
-
-
79959350721
-
NLRX1 protein attenuates inflammatory responses to infection by interfering with the RIG-I-MAVS and TRAF6-NF-kappaB signaling pathways
-
doi:10.1016/j.immuni.2011.03.026
-
Allen IC, Moore CB, Schneider M, Lei Y, Davis BK, Scull MA, et al. NLRX1 protein attenuates inflammatory responses to infection by interfering with the RIG-I-MAVS and TRAF6-NF-kappaB signaling pathways. Immunity (2011) 34:854-65. doi:10.1016/j.immuni.2011.03.026
-
(2011)
Immunity
, vol.34
, pp. 854-865
-
-
Allen, I.C.1
Moore, C.B.2
Schneider, M.3
Lei, Y.4
Davis, B.K.5
Scull, M.A.6
-
54
-
-
79959329537
-
NLRX1 negatively regulates TLR-induced NF-kappaB signaling by targeting TRAF6 and IKK
-
doi:10.1016/j.immuni.2011.02.022
-
Xia X, Cui J, Wang HY, Zhu L, Matsueda S, Wang Q, et al. NLRX1 negatively regulates TLR-induced NF-kappaB signaling by targeting TRAF6 and IKK. Immunity (2011) 34:843-53. doi:10.1016/j.immuni.2011.02.022
-
(2011)
Immunity
, vol.34
, pp. 843-853
-
-
Xia, X.1
Cui, J.2
Wang, H.Y.3
Zhu, L.4
Matsueda, S.5
Wang, Q.6
-
55
-
-
84863005844
-
The mitochondrial proteins NLRX1 and TUFM form a complex that regulates type I interferon and autophagy
-
doi:10.1016/j.immuni.2012.03.025
-
Lei Y, Wen H, Yu Y, Taxman DJ, Zhang L, Widman DG, et al. The mitochondrial proteins NLRX1 and TUFM form a complex that regulates type I interferon and autophagy. Immunity (2012) 36:933-46. doi:10.1016/j.immuni.2012.03.025
-
(2012)
Immunity
, vol.36
, pp. 933-946
-
-
Lei, Y.1
Wen, H.2
Yu, Y.3
Taxman, D.J.4
Zhang, L.5
Widman, D.G.6
-
56
-
-
84877344662
-
The NLR protein, NLRX1, and its partner, TUFM, reduce type I interferon, and enhance autophagy
-
doi:10.4161/auto.23026
-
Lei Y, Wen H, Ting JP. The NLR protein, NLRX1, and its partner, TUFM, reduce type I interferon, and enhance autophagy. Autophagy (2013) 9:432-3. doi:10.4161/auto.23026
-
(2013)
Autophagy
, vol.9
, pp. 432-433
-
-
Lei, Y.1
Wen, H.2
Ting, J.P.3
-
57
-
-
40249111682
-
NLRX1 is a mitochondrial NOD-like receptor that amplifies NF-kappaB and JNK pathways by inducing reactive oxygen species production
-
doi:10.1038/sj.embor.7401161
-
Tattoli I, Carneiro LA, Jehanno M, Magalhaes JG, Shu Y, Philpott DJ, et al. NLRX1 is a mitochondrial NOD-like receptor that amplifies NF-kappaB and JNK pathways by inducing reactive oxygen species production. EMBO Rep (2008) 9:293-300. doi:10.1038/sj.embor.7401161
-
(2008)
EMBO Rep
, vol.9
, pp. 293-300
-
-
Tattoli, I.1
Carneiro, L.A.2
Jehanno, M.3
Magalhaes, J.G.4
Shu, Y.5
Philpott, D.J.6
-
58
-
-
78650630756
-
Enhancement of reactive oxygen species production and chlamydial infection by the mitochondrial Nod-like family member NLRX1
-
doi:10.1074/jbc.M110.137885
-
Abdul-Sater AA, Said-Sadier N, Lam VM, Singh B, Pettengill MA, Soares F, et al. Enhancement of reactive oxygen species production and chlamydial infection by the mitochondrial Nod-like family member NLRX1. J Biol Chem (2010) 285:41637-45. doi:10.1074/jbc.M110.137885
-
(2010)
J Biol Chem
, vol.285
, pp. 41637-41645
-
-
Abdul-Sater, A.A.1
Said-Sadier, N.2
Lam, V.M.3
Singh, B.4
Pettengill, M.A.5
Soares, F.6
-
59
-
-
84880299261
-
NLRX1 does not inhibit MAVS-dependent antiviral signalling
-
doi:10.1177/1753425912467383
-
Soares F, Tattoli I, Wortzman ME, Arnoult D, Philpott DJ, Girardin SE. NLRX1 does not inhibit MAVS-dependent antiviral signalling. Innate Immun (2013) 19:438-48. doi:10.1177/1753425912467383
-
(2013)
Innate Immun
, vol.19
, pp. 438-448
-
-
Soares, F.1
Tattoli, I.2
Wortzman, M.E.3
Arnoult, D.4
Philpott, D.J.5
Girardin, S.E.6
-
60
-
-
79960205819
-
NLRX1/NOD5 deficiency does not affect MAVS signalling
-
doi:10.1038/cdd.2011.64
-
Rebsamen M, Vazquez J, Tardivel A, Guarda G, Curran J, Tschopp J. NLRX1/NOD5 deficiency does not affect MAVS signalling. Cell Death Differ (2011) 18:1387. doi:10.1038/cdd.2011.64
-
(2011)
Cell Death Differ
, vol.18
, pp. 1387
-
-
Rebsamen, M.1
Vazquez, J.2
Tardivel, A.3
Guarda, G.4
Curran, J.5
Tschopp, J.6
-
61
-
-
84858677223
-
Sensing and reacting to microbes through the inflammasomes
-
doi:10.1038/ni.2231
-
Franchi L, Munoz-Planillo R, Nunez G. Sensing and reacting to microbes through the inflammasomes. Nat Immunol (2012) 13:325-32. doi:10.1038/ni.2231
-
(2012)
Nat Immunol
, vol.13
, pp. 325-332
-
-
Franchi, L.1
Munoz-Planillo, R.2
Nunez, G.3
-
62
-
-
58149159542
-
Common variants in the NLRP3 region contribute to Crohn's disease susceptibility
-
doi:10.1038/ng.285
-
Villani AC, Lemire M, Fortin G, Louis E, Silverberg MS, Collette C, et al. Common variants in the NLRP3 region contribute to Crohn's disease susceptibility. Nat Genet (2009) 41:71-6. doi:10.1038/ng.285
-
(2009)
Nat Genet
, vol.41
, pp. 71-76
-
-
Villani, A.C.1
Lemire, M.2
Fortin, G.3
Louis, E.4
Silverberg, M.S.5
Collette, C.6
-
63
-
-
80052962565
-
Role of NOD1/CARD4 and NOD2/CARD15 gene polymorphisms in cancer etiology
-
doi:10.1016/j.humimm.2011.06.003
-
Kutikhin AG. Role of NOD1/CARD4 and NOD2/CARD15 gene polymorphisms in cancer etiology. Hum Immunol (2011) 72:955-68. doi:10.1016/j.humimm.2011.06.003
-
(2011)
Hum Immunol
, vol.72
, pp. 955-968
-
-
Kutikhin, A.G.1
-
64
-
-
84868336049
-
Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease
-
doi:10.1038/nature11582
-
Jostins L, Ripke S, Weersma RK, Duerr RH, Mcgovern DP, Hui KY, et al. Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease. Nature (2012) 491:119-24. doi:10.1038/nature11582
-
(2012)
Nature
, vol.491
, pp. 119-124
-
-
Jostins, L.1
Ripke, S.2
Weersma, R.K.3
Duerr, R.H.4
Mcgovern, D.P.5
Hui, K.Y.6
-
65
-
-
0038824980
-
An essential role for NOD1 in host recognition of bacterial peptidoglycan containing diaminopimelic acid
-
doi:10.1038/ni945
-
Chamaillard M, Hashimoto M, Horie Y, Masumoto J, Qiu S, Saab L, et al. An essential role for NOD1 in host recognition of bacterial peptidoglycan containing diaminopimelic acid. Nat Immunol (2003) 4:702-7. doi:10.1038/ni945
-
(2003)
Nat Immunol
, vol.4
, pp. 702-707
-
-
Chamaillard, M.1
Hashimoto, M.2
Horie, Y.3
Masumoto, J.4
Qiu, S.5
Saab, L.6
-
66
-
-
0038615855
-
Nod1 detects a unique muropeptide from gram-negative bacterial peptidoglycan
-
doi:10.1126/science.1084677
-
Girardin SE, Boneca IG, Carneiro LA, Antignac A, Jehanno M, Viala J, et al. Nod1 detects a unique muropeptide from gram-negative bacterial peptidoglycan. Science (2003) 300:1584-7. doi:10.1126/science.1084677
-
(2003)
Science
, vol.300
, pp. 1584-1587
-
-
Girardin, S.E.1
Boneca, I.G.2
Carneiro, L.A.3
Antignac, A.4
Jehanno, M.5
Viala, J.6
-
67
-
-
0142180157
-
Peptidoglycan molecular requirements allowing detection by Nod1 and Nod2
-
doi:10.1074/jbc.M307198200
-
Girardin SE, Travassos LH, Herve M, Blanot D, Boneca IG, Philpott DJ, et al. Peptidoglycan molecular requirements allowing detection by Nod1 and Nod2. J Biol Chem (2003) 278:41702-8. doi:10.1074/jbc.M307198200
-
(2003)
J Biol Chem
, vol.278
, pp. 41702-41708
-
-
Girardin, S.E.1
Travassos, L.H.2
Herve, M.3
Blanot, D.4
Boneca, I.G.5
Philpott, D.J.6
-
68
-
-
10744222688
-
Expression of NOD2 in Paneth cells: a possible link to Crohn's ileitis
-
doi:10.1136/gut.52.11.1591
-
Ogura Y, Lala S, Xin W, Smith E, Dowds TA, Chen FF, et al. Expression of NOD2 in Paneth cells: a possible link to Crohn's ileitis. Gut (2003) 52:1591-7. doi:10.1136/gut.52.11.1591
-
(2003)
Gut
, vol.52
, pp. 1591-1597
-
-
Ogura, Y.1
Lala, S.2
Xin, W.3
Smith, E.4
Dowds, T.A.5
Chen, F.F.6
-
69
-
-
0012722659
-
Nod2 is a general sensor of peptidoglycan through muramyl dipeptide (MDP) detection
-
doi:10.1074/jbc.C200651200
-
Girardin SE, Boneca IG, Viala J, Chamaillard M, Labigne A, Thomas G, et al. Nod2 is a general sensor of peptidoglycan through muramyl dipeptide (MDP) detection. J Biol Chem (2003) 278:8869-72. doi:10.1074/jbc.C200651200
-
(2003)
J Biol Chem
, vol.278
, pp. 8869-8872
-
-
Girardin, S.E.1
Boneca, I.G.2
Viala, J.3
Chamaillard, M.4
Labigne, A.5
Thomas, G.6
-
70
-
-
9244245293
-
Nod1 responds to peptidoglycan delivered by the Helicobacter pylori cag pathogenicity island
-
doi:10.1038/ni1131
-
Viala J, Chaput C, Boneca IG, Cardona A, Girardin SE, Moran AP, et al. Nod1 responds to peptidoglycan delivered by the Helicobacter pylori cag pathogenicity island. Nat Immunol (2004) 5:1166-74. doi:10.1038/ni1131
-
(2004)
Nat Immunol
, vol.5
, pp. 1166-1174
-
-
Viala, J.1
Chaput, C.2
Boneca, I.G.3
Cardona, A.4
Girardin, S.E.5
Moran, A.P.6
-
71
-
-
69949125920
-
pH-dependent internalization of muramyl peptides from early endosomes enables Nod1 and Nod2 signaling
-
doi:10.1074/jbc.M109.033670
-
Lee J, Tattoli I, Wojtal KA, Vavricka SR, Philpott DJ, Girardin SE. pH-dependent internalization of muramyl peptides from early endosomes enables Nod1 and Nod2 signaling. J Biol Chem (2009) 284:23818-29. doi:10.1074/jbc.M109.033670
-
(2009)
J Biol Chem
, vol.284
, pp. 23818-23829
-
-
Lee, J.1
Tattoli, I.2
Wojtal, K.A.3
Vavricka, S.R.4
Philpott, D.J.5
Girardin, S.E.6
-
72
-
-
64249166480
-
Clathrin- and dynamin-dependent endocytic pathway regulates muramyl dipeptide internalization and NOD2 activation
-
doi:10.4049/jimmunol.0802197
-
Marina-Garcia N, Franchi L, Kim YG, Hu Y, Smith DE, Boons GJ, et al. Clathrin- and dynamin-dependent endocytic pathway regulates muramyl dipeptide internalization and NOD2 activation. J Immunol (2009) 182:4321-7. doi:10.4049/jimmunol.0802197
-
(2009)
J Immunol
, vol.182
, pp. 4321-4327
-
-
Marina-Garcia, N.1
Franchi, L.2
Kim, Y.G.3
Hu, Y.4
Smith, D.E.5
Boons, G.J.6
-
73
-
-
84899953763
-
Endosomes are specialized platforms for bacterial sensing and NOD2 signalling
-
doi:10.1038/nature13133
-
Nakamura N, Lill JR, Phung Q, Jiang Z, Bakalarski C, De Maziere A, et al. Endosomes are specialized platforms for bacterial sensing and NOD2 signalling. Nature (2014) 509:240-4. doi:10.1038/nature13133
-
(2014)
Nature
, vol.509
, pp. 240-244
-
-
Nakamura, N.1
Lill, J.R.2
Phung, Q.3
Jiang, Z.4
Bakalarski, C.5
De Maziere, A.6
-
74
-
-
57149093623
-
GEF-H1 mediated control of NOD1 dependent NF-kappaB activation by Shigella effectors
-
doi:10.1371/journal.ppat.1000228
-
Fukazawa A, Alonso C, Kurachi K, Gupta S, Lesser CF, Mccormick BA, et al. GEF-H1 mediated control of NOD1 dependent NF-kappaB activation by Shigella effectors. PLoS Pathog (2008) 4:e1000228. doi:10.1371/journal.ppat.1000228
-
(2008)
PLoS Pathog
, vol.4
-
-
Fukazawa, A.1
Alonso, C.2
Kurachi, K.3
Gupta, S.4
Lesser, C.F.5
Mccormick, B.A.6
-
75
-
-
38049177193
-
The pattern-recognition molecule Nod1 is localized at the plasma membrane at sites of bacterial interaction
-
Kufer TA, Kremmer E, Adam AC, Philpott DJ, Sansonetti PJ. The pattern-recognition molecule Nod1 is localized at the plasma membrane at sites of bacterial interaction. Cell Microbiol (2008) 10:477-86.
-
(2008)
Cell Microbiol
, vol.10
, pp. 477-486
-
-
Kufer, T.A.1
Kremmer, E.2
Adam, A.C.3
Philpott, D.J.4
Sansonetti, P.J.5
-
76
-
-
84876282419
-
Manipulation of small Rho GTPases is a pathogen-induced process detected by NOD1
-
doi:10.1038/nature12025
-
Keestra AM, Winter MG, Auburger JJ, Frassle SP, Xavier MN, Winter SE, et al. Manipulation of small Rho GTPases is a pathogen-induced process detected by NOD1. Nature (2013) 496:233-7. doi:10.1038/nature12025
-
(2013)
Nature
, vol.496
, pp. 233-237
-
-
Keestra, A.M.1
Winter, M.G.2
Auburger, J.J.3
Frassle, S.P.4
Xavier, M.N.5
Winter, S.E.6
-
77
-
-
0037075549
-
Involvement of receptor-interacting protein 2 in innate and adaptive immune responses
-
doi:10.1038/416190a
-
Chin AI, Dempsey PW, Bruhn K, Miller JF, Xu Y, Cheng G. Involvement of receptor-interacting protein 2 in innate and adaptive immune responses. Nature (2002) 416:190-4. doi:10.1038/416190a
-
(2002)
Nature
, vol.416
, pp. 190-194
-
-
Chin, A.I.1
Dempsey, P.W.2
Bruhn, K.3
Miller, J.F.4
Xu, Y.5
Cheng, G.6
-
78
-
-
33846936219
-
RICK/RIP2 mediates innate immune responses induced through Nod1 and Nod2 but not TLRs
-
doi:10.4049/jimmunol.178.4.2380
-
Park JH, Kim YG, Mcdonald C, Kanneganti TD, Hasegawa M, Body-Malapel M, et al. RICK/RIP2 mediates innate immune responses induced through Nod1 and Nod2 but not TLRs. J Immunol (2007) 178:2380-6. doi:10.4049/jimmunol.178.4.2380
-
(2007)
J Immunol
, vol.178
, pp. 2380-2386
-
-
Park, J.H.1
Kim, Y.G.2
Mcdonald, C.3
Kanneganti, T.D.4
Hasegawa, M.5
Body-Malapel, M.6
-
79
-
-
77951784552
-
NOD1 contributes to mouse host defense against Helicobacter pylori via induction of type I IFN and activation of the ISGF3 signaling pathway
-
doi:10.1172/JCI39481
-
Watanabe T, Asano N, Fichtner-Feigl S, Gorelick PL, Tsuji Y, Matsumoto Y, et al. NOD1 contributes to mouse host defense against Helicobacter pylori via induction of type I IFN and activation of the ISGF3 signaling pathway. J Clin Invest (2010) 120:1645-62. doi:10.1172/JCI39481
-
(2010)
J Clin Invest
, vol.120
, pp. 1645-1662
-
-
Watanabe, T.1
Asano, N.2
Fichtner-Feigl, S.3
Gorelick, P.L.4
Tsuji, Y.5
Matsumoto, Y.6
-
80
-
-
79955129532
-
Essential role of Rip2 in the modulation of innate and adaptive immunity triggered by Nod1 and Nod2 ligands
-
doi:10.1002/eji.201040827
-
Magalhaes JG, Lee J, Geddes K, Rubino S, Philpott DJ, Girardin SE. Essential role of Rip2 in the modulation of innate and adaptive immunity triggered by Nod1 and Nod2 ligands. Eur J Immunol (2011) 41:1445-55. doi:10.1002/eji.201040827
-
(2011)
Eur J Immunol
, vol.41
, pp. 1445-1455
-
-
Magalhaes, J.G.1
Lee, J.2
Geddes, K.3
Rubino, S.4
Philpott, D.J.5
Girardin, S.E.6
-
81
-
-
0034623225
-
An induced proximity model for NF-kappa B activation in the Nod1/RICK and RIP signaling pathways
-
Inohara N, Koseki T, Lin J, Del Peso L, Lucas PC, Chen FF, et al. An induced proximity model for NF-kappa B activation in the Nod1/RICK and RIP signaling pathways. J Biol Chem (2000) 275:27823-31.
-
(2000)
J Biol Chem
, vol.275
, pp. 27823-27831
-
-
Inohara, N.1
Koseki, T.2
Lin, J.3
Del Peso, L.4
Lucas, P.C.5
Chen, F.F.6
-
82
-
-
0032524908
-
RICK, a novel protein kinase containing a caspase recruitment domain, interacts with CLARP and regulates CD95-mediated apoptosis
-
doi:10.1074/jbc.273.20.12296
-
Inohara N, Del Peso L, Koseki T, Chen S, Nunez G. RICK, a novel protein kinase containing a caspase recruitment domain, interacts with CLARP and regulates CD95-mediated apoptosis. J Biol Chem (1998) 273:12296-300. doi:10.1074/jbc.273.20.12296
-
(1998)
J Biol Chem
, vol.273
, pp. 12296-12300
-
-
Inohara, N.1
Del Peso, L.2
Koseki, T.3
Chen, S.4
Nunez, G.5
-
83
-
-
0032479145
-
RIP2 is a novel NF-kappaB-activating and cell death-inducing kinase
-
doi:10.1074/jbc.273.27.16968
-
McCarthy JV, Ni J, Dixit VM. RIP2 is a novel NF-kappaB-activating and cell death-inducing kinase. J Biol Chem (1998) 273:16968-75. doi:10.1074/jbc.273.27.16968
-
(1998)
J Biol Chem
, vol.273
, pp. 16968-16975
-
-
McCarthy, J.V.1
Ni, J.2
Dixit, V.M.3
-
84
-
-
0032537836
-
Identification of CARDIAK, a RIP-like kinase that associates with caspase-1
-
doi:10.1016/S0960-9822(07)00352-1
-
Thome M, Hofmann K, Burns K, Martinon F, Bodmer JL, Mattmann C, et al. Identification of CARDIAK, a RIP-like kinase that associates with caspase-1. Curr Biol (1998) 8:885-8. doi:10.1016/S0960-9822(07)00352-1
-
(1998)
Curr Biol
, vol.8
, pp. 885-888
-
-
Thome, M.1
Hofmann, K.2
Burns, K.3
Martinon, F.4
Bodmer, J.L.5
Mattmann, C.6
-
85
-
-
10744228362
-
RICK activates a NF-kappaB-dependent anti-human cytomegalovirus response
-
doi:10.1074/jbc.M312893200
-
Eickhoff J, Hanke M, Stein-Gerlach M, Kiang TP, Herzberger K, Habenberger P, et al. RICK activates a NF-kappaB-dependent anti-human cytomegalovirus response. J Biol Chem (2004) 279:9642-52. doi:10.1074/jbc.M312893200
-
(2004)
J Biol Chem
, vol.279
, pp. 9642-9652
-
-
Eickhoff, J.1
Hanke, M.2
Stein-Gerlach, M.3
Kiang, T.P.4
Herzberger, K.5
Habenberger, P.6
-
86
-
-
34249826059
-
Molecular mechanisms involved in the regulation of cytokine production by muramyl dipeptide
-
doi:10.1042/BJ20061704
-
Windheim M, Lang C, Peggie M, Plater LA, Cohen P. Molecular mechanisms involved in the regulation of cytokine production by muramyl dipeptide. Biochem J (2007) 404:179-90. doi:10.1042/BJ20061704
-
(2007)
Biochem J
, vol.404
, pp. 179-190
-
-
Windheim, M.1
Lang, C.2
Peggie, M.3
Plater, L.A.4
Cohen, P.5
-
87
-
-
67749095245
-
The kinase activity of Rip2 determines its stability and consequently Nod1- and Nod2-mediated immune responses
-
doi:10.1074/jbc.M109.006353
-
Nembrini C, Kisielow J, Shamshiev AT, Tortola L, Coyle AJ, Kopf M, et al. The kinase activity of Rip2 determines its stability and consequently Nod1- and Nod2-mediated immune responses. J Biol Chem (2009) 284:19183-8. doi:10.1074/jbc.M109.006353
-
(2009)
J Biol Chem
, vol.284
, pp. 19183-19188
-
-
Nembrini, C.1
Kisielow, J.2
Shamshiev, A.T.3
Tortola, L.4
Coyle, A.J.5
Kopf, M.6
-
88
-
-
37548999003
-
NOD2 pathway activation by MDP or Mycobacterium tuberculosis infection involves the stable polyubiquitination of Rip2
-
doi:10.1074/jbc.M703079200
-
Yang Y, Yin C, Pandey A, Abbott D, Sassetti C, Kelliher MA. NOD2 pathway activation by MDP or Mycobacterium tuberculosis infection involves the stable polyubiquitination of Rip2. J Biol Chem (2007) 282:36223-9. doi:10.1074/jbc.M703079200
-
(2007)
J Biol Chem
, vol.282
, pp. 36223-36229
-
-
Yang, Y.1
Yin, C.2
Pandey, A.3
Abbott, D.4
Sassetti, C.5
Kelliher, M.A.6
-
89
-
-
38549084725
-
A critical role of RICK/RIP2 polyubiquitination in Nod-induced NF-kappaB activation
-
doi:10.1038/sj.emboj.7601962
-
Hasegawa M, Fujimoto Y, Lucas PC, Nakano H, Fukase K, Nunez G, et al. A critical role of RICK/RIP2 polyubiquitination in Nod-induced NF-kappaB activation. EMBO J (2008) 27:373-83. doi:10.1038/sj.emboj.7601962
-
(2008)
EMBO J
, vol.27
, pp. 373-383
-
-
Hasegawa, M.1
Fujimoto, Y.2
Lucas, P.C.3
Nakano, H.4
Fukase, K.5
Nunez, G.6
-
90
-
-
78649890151
-
Inhibition of RIP2's tyrosine kinase activity limits NOD2-driven cytokine responses
-
doi:10.1101/gad.1964410
-
Tigno-Aranjuez JT, Asara JM, Abbott DW. Inhibition of RIP2's tyrosine kinase activity limits NOD2-driven cytokine responses. Genes Dev (2010) 24:2666-77. doi:10.1101/gad.1964410
-
(2010)
Genes Dev
, vol.24
, pp. 2666-2677
-
-
Tigno-Aranjuez, J.T.1
Asara, J.M.2
Abbott, D.W.3
-
91
-
-
11144289688
-
The Crohn's disease protein, NOD2, requires RIP2 in order to induce ubiquitinylation of a novel site on NEMO
-
doi:10.1016/j.cub.2004.12.032
-
Abbott DW, Wilkins A, Asara JM, Cantley LC. The Crohn's disease protein, NOD2, requires RIP2 in order to induce ubiquitinylation of a novel site on NEMO. Curr Biol (2004) 14:2217-27. doi:10.1016/j.cub.2004.12.032
-
(2004)
Curr Biol
, vol.14
, pp. 2217-2227
-
-
Abbott, D.W.1
Wilkins, A.2
Asara, J.M.3
Cantley, L.C.4
-
92
-
-
34548225910
-
Coordinated regulation of Toll-like receptor and NOD2 signaling by K63-linked polyubiquitin chains
-
doi:10.1128/MCB.00270-07
-
Abbott DW, Yang Y, Hutti JE, Madhavarapu S, Kelliher MA, Cantley LC. Coordinated regulation of Toll-like receptor and NOD2 signaling by K63-linked polyubiquitin chains. Mol Cell Biol (2007) 27:6012-25. doi:10.1128/MCB.00270-07
-
(2007)
Mol Cell Biol
, vol.27
, pp. 6012-6025
-
-
Abbott, D.W.1
Yang, Y.2
Hutti, J.E.3
Madhavarapu, S.4
Kelliher, M.A.5
Cantley, L.C.6
-
93
-
-
0033584841
-
RIP2 is a Raf1-activated mitogen-activated protein kinase kinase
-
doi:10.1074/jbc.274.47.33684
-
Navas TA, Baldwin DT, Stewart TA. RIP2 is a Raf1-activated mitogen-activated protein kinase kinase. J Biol Chem (1999) 274:33684-90. doi:10.1074/jbc.274.47.33684
-
(1999)
J Biol Chem
, vol.274
, pp. 33684-33690
-
-
Navas, T.A.1
Baldwin, D.T.2
Stewart, T.A.3
-
94
-
-
66949138341
-
Cellular inhibitors of apoptosis cIAP1 and cIAP2 are required for innate immunity signaling by the pattern recognition receptors NOD1 and NOD2
-
DoironK, Labbe K., Korneluk RG, Barker PA, Saleh M.
-
Bertrand MJ, Doiron K, Labbe K, Korneluk RG, Barker PA, Saleh M. Cellular inhibitors of apoptosis cIAP1 and cIAP2 are required for innate immunity signaling by the pattern recognition receptors NOD1 and NOD2. Immunity (2009) 30:789-801. doi:10.1016/j.immuni.2009.04.011
-
(2009)
Immunity
, vol.30
, pp. 789-801
-
-
Bertrand, M.J.1
-
95
-
-
70149099161
-
XIAP mediates NOD signaling via interaction with RIP2
-
doi:10.1073/pnas.0907131106
-
Krieg A, Correa RG, Garrison JB, Le Negrate G, Welsh K, Huang Z, et al. XIAP mediates NOD signaling via interaction with RIP2. Proc Natl Acad Sci U S A (2009) 106:14524-9. doi:10.1073/pnas.0907131106
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 14524-14529
-
-
Krieg, A.1
Correa, R.G.2
Garrison, J.B.3
Le Negrate, G.4
Welsh, K.5
Huang, Z.6
-
96
-
-
84863000898
-
The ubiquitin ligase XIAP recruits LUBAC for NOD2 signaling in inflammation and innate immunity
-
doi:10.1016/j.molcel.2012.04.014
-
Damgaard RB, Nachbur U, Yabal M, Wong WW, Fiil BK, Kastirr M, et al. The ubiquitin ligase XIAP recruits LUBAC for NOD2 signaling in inflammation and innate immunity. Mol Cell (2012) 46:746-58. doi:10.1016/j.molcel.2012.04.014
-
(2012)
Mol Cell
, vol.46
, pp. 746-758
-
-
Damgaard, R.B.1
Nachbur, U.2
Yabal, M.3
Wong, W.W.4
Fiil, B.K.5
Kastirr, M.6
-
97
-
-
84867905831
-
Linear ubiquitination: a novel NF-kappaB regulatory mechanism for inflammatory and immune responses by the LUBAC ubiquitin ligase complex
-
doi:10.1507/endocrj.EJ12-0148
-
Tokunaga F, Iwai K. Linear ubiquitination: a novel NF-kappaB regulatory mechanism for inflammatory and immune responses by the LUBAC ubiquitin ligase complex. Endocr J (2012) 59:641-52. doi:10.1507/endocrj.EJ12-0148
-
(2012)
Endocr J
, vol.59
, pp. 641-652
-
-
Tokunaga, F.1
Iwai, K.2
-
98
-
-
84880774323
-
Disease-causing mutations in the XIAP BIR2 domain impair NOD2-dependent immune signalling
-
doi:10.1002/emmm.201303090
-
Damgaard RB, Fiil BK, Speckmann C, Yabal M, Zur Stadt U, Bekker-Jensen S, et al. Disease-causing mutations in the XIAP BIR2 domain impair NOD2-dependent immune signalling. EMBO Mol Med (2013) 5:1278-95. doi:10.1002/emmm.201303090
-
(2013)
EMBO Mol Med
, vol.5
, pp. 1278-1295
-
-
Damgaard, R.B.1
Fiil, B.K.2
Speckmann, C.3
Yabal, M.4
Zur Stadt, U.5
Bekker-Jensen, S.6
-
99
-
-
38849163741
-
Muramyl dipeptide activation of nucleotide-binding oligomerization domain 2 protects mice from experimental colitis
-
doi:10.1172/JCI33145
-
Watanabe T, Asano N, Murray PJ, Ozato K, Tailor P, Fuss IJ, et al. Muramyl dipeptide activation of nucleotide-binding oligomerization domain 2 protects mice from experimental colitis. J Clin Invest (2008) 118:545-59. doi:10.1172/JCI33145
-
(2008)
J Clin Invest
, vol.118
, pp. 545-559
-
-
Watanabe, T.1
Asano, N.2
Murray, P.J.3
Ozato, K.4
Tailor, P.5
Fuss, I.J.6
-
100
-
-
66949174458
-
cIAP proteins: keystones in NOD receptor signal transduction
-
doi:10.1016/j.immuni.2009.06.005
-
Reardon C, Mak TW. cIAP proteins: keystones in NOD receptor signal transduction. Immunity (2009) 30:755-6. doi:10.1016/j.immuni.2009.06.005
-
(2009)
Immunity
, vol.30
, pp. 755-756
-
-
Reardon, C.1
Mak, T.W.2
-
101
-
-
79957962932
-
Non-apoptotic role of BID in inflammation and innate immunity
-
DoironK, Fitzgerald P., Dillon CP, Green DR, et al.
-
Yeretssian G, Correa RG, Doiron K, Fitzgerald P, Dillon CP, Green DR, et al. Non-apoptotic role of BID in inflammation and innate immunity. Nature (2011) 474:96-9. doi:10.1038/nature09982
-
(2011)
Nature
, vol.474
, pp. 96-99
-
-
Yeretssian, G.1
Correa, R.G.2
-
102
-
-
68149170034
-
ITCH K63-ubiquitinates the NOD2 binding protein, RIP2, to influence inflammatory signaling pathways
-
doi:10.1016/j.cub.2009.06.038
-
Tao M, Scacheri PC, Marinis JM, Harhaj EW, Matesic LE, Abbott DW. ITCH K63-ubiquitinates the NOD2 binding protein, RIP2, to influence inflammatory signaling pathways. Curr Biol (2009) 19:1255-63. doi:10.1016/j.cub.2009.06.038
-
(2009)
Curr Biol
, vol.19
, pp. 1255-1263
-
-
Tao, M.1
Scacheri, P.C.2
Marinis, J.M.3
Harhaj, E.W.4
Matesic, L.E.5
Abbott, D.W.6
-
103
-
-
44949240664
-
cIAP1 and cIAP2 facilitate cancer cell survival by functioning as E3 ligases that promote RIP1 ubiquitination
-
doi:10.1016/j.molcel.2008.05.014
-
Bertrand MJ, Milutinovic S, Dickson KM, Ho WC, Boudreault A, Durkin J, et al. cIAP1 and cIAP2 facilitate cancer cell survival by functioning as E3 ligases that promote RIP1 ubiquitination. Mol Cell (2008) 30:689-700. doi:10.1016/j.molcel.2008.05.014
-
(2008)
Mol Cell
, vol.30
, pp. 689-700
-
-
Bertrand, M.J.1
Milutinovic, S.2
Dickson, K.M.3
Ho, W.C.4
Boudreault, A.5
Durkin, J.6
-
104
-
-
32444445124
-
Nod1-dependent control of tumor growth
-
doi:10.1073/pnas.0509228103
-
da Silva Correia J, Miranda Y, Austin-Brown N, Hsu J, Mathison J, Xiang R, et al. Nod1-dependent control of tumor growth. Proc Natl Acad Sci U S A (2006) 103:1840-5. doi:10.1073/pnas.0509228103
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 1840-1845
-
-
da Silva, C.J.1
Miranda, Y.2
Austin-Brown, N.3
Hsu, J.4
Mathison, J.5
Xiang, R.6
-
105
-
-
33947379719
-
Regulation of Nod1-mediated signaling pathways
-
doi:10.1038/sj.cdd.4402070
-
da Silva Correia J, Miranda Y, Leonard N, Hsu J, Ulevitch RJ. Regulation of Nod1-mediated signaling pathways. Cell Death Differ (2007) 14:830-9. doi:10.1038/sj.cdd.4402070
-
(2007)
Cell Death Differ
, vol.14
, pp. 830-839
-
-
da Silva, C.J.1
Miranda, Y.2
Leonard, N.3
Hsu, J.4
Ulevitch, R.J.5
-
106
-
-
51349096358
-
Molecular regulation of inflammation and cell death
-
doi:10.1016/j.cyto.2008.07.015
-
Yeretssian G, Labbe K, Saleh M. Molecular regulation of inflammation and cell death. Cytokine (2008) 43:380-90. doi:10.1016/j.cyto.2008.07.015
-
(2008)
Cytokine
, vol.43
, pp. 380-390
-
-
Yeretssian, G.1
Labbe, K.2
Saleh, M.3
-
107
-
-
84859433796
-
Non-apoptotic functions of apoptosis-regulatory proteins
-
doi:10.1038/embor.2012.19
-
Galluzzi L, Kepp O, Trojel-Hansen C, Kroemer G. Non-apoptotic functions of apoptosis-regulatory proteins. EMBO Rep (2012) 13:322-30. doi:10.1038/embor.2012.19
-
(2012)
EMBO Rep
, vol.13
, pp. 322-330
-
-
Galluzzi, L.1
Kepp, O.2
Trojel-Hansen, C.3
Kroemer, G.4
-
108
-
-
84865205213
-
Is BID required for NOD signalling? reply
-
DoironK, Fitzgerald P., Dillon CP, Green DR, et al.
-
Yeretssian G, Correa RG, Doiron K, Fitzgerald P, Dillon CP, Green DR, et al. Is BID required for NOD signalling? reply. Nature (2012) 488:E6-8. doi:10.1038/nature11367
-
(2012)
Nature
, vol.488
-
-
Yeretssian, G.1
Correa, R.G.2
-
109
-
-
84865251377
-
Is BID required for NOD signalling?
-
doi:10.1038/nature11366
-
Nachbur U, Vince JE, O'Reilly LA, Strasser A, Silke J. Is BID required for NOD signalling? Nature (2012) 488:E4-6. doi:10.1038/nature11366
-
(2012)
Nature
, vol.488
-
-
Nachbur, U.1
Vince, J.E.2
O'Reilly, L.A.3
Strasser, A.4
Silke, J.5
-
110
-
-
33846627302
-
A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1
-
doi:10.1038/ng1954
-
Hampe J, Franke A, Rosenstiel P, Till A, Teuber M, Huse K, et al. A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1. Nat Genet (2007) 39:207-11. doi:10.1038/ng1954
-
(2007)
Nat Genet
, vol.39
, pp. 207-211
-
-
Hampe, J.1
Franke, A.2
Rosenstiel, P.3
Till, A.4
Teuber, M.5
Huse, K.6
-
111
-
-
34247554965
-
Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis
-
doi:10.1038/ng2032
-
Rioux JD, Xavier RJ, Taylor KD, Silverberg MS, Goyette P, Huett A, et al. Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis. Nat Genet (2007) 39:596-604. doi:10.1038/ng2032
-
(2007)
Nat Genet
, vol.39
, pp. 596-604
-
-
Rioux, J.D.1
Xavier, R.J.2
Taylor, K.D.3
Silverberg, M.S.4
Goyette, P.5
Huett, A.6
-
112
-
-
73849121209
-
Nod1 and Nod2 direct autophagy by recruiting ATG16L1 to the plasma membrane at the site of bacterial entry
-
doi:10.1038/ni.1823
-
Travassos LH, Carneiro LA, Ramjeet M, Hussey S, Kim YG, Magalhaes JG, et al. Nod1 and Nod2 direct autophagy by recruiting ATG16L1 to the plasma membrane at the site of bacterial entry. Nat Immunol (2010) 11:55-62. doi:10.1038/ni.1823
-
(2010)
Nat Immunol
, vol.11
, pp. 55-62
-
-
Travassos, L.H.1
Carneiro, L.A.2
Ramjeet, M.3
Hussey, S.4
Kim, Y.G.5
Magalhaes, J.G.6
-
113
-
-
73849151394
-
NOD2 stimulation induces autophagy in dendritic cells influencing bacterial handling and antigen presentation
-
doi:10.1038/nm.2069
-
Cooney R, Baker J, Brain O, Danis B, Pichulik T, Allan P, et al. NOD2 stimulation induces autophagy in dendritic cells influencing bacterial handling and antigen presentation. Nat Med (2010) 16:90-7. doi:10.1038/nm.2069
-
(2010)
Nat Med
, vol.16
, pp. 90-97
-
-
Cooney, R.1
Baker, J.2
Brain, O.3
Danis, B.4
Pichulik, T.5
Allan, P.6
-
114
-
-
77957682295
-
ATG16L1 and NOD2 interact in an autophagy-dependent antibacterial pathway implicated in Crohn's disease pathogenesis
-
doi:10.1053/j.gastro.2010.07.006
-
Homer CR, Richmond AL, Rebert NA, Achkar JP, Mcdonald C. ATG16L1 and NOD2 interact in an autophagy-dependent antibacterial pathway implicated in Crohn's disease pathogenesis. Gastroenterology (2010) 139:1630-41. doi:10.1053/j.gastro.2010.07.006
-
(2010)
Gastroenterology
, vol.139
, pp. 1630-1641
-
-
Homer, C.R.1
Richmond, A.L.2
Rebert, N.A.3
Achkar, J.P.4
Mcdonald, C.5
-
115
-
-
84864094479
-
A dual role for receptor-interacting protein kinase 2 (RIP2) kinase activity in nucleotide-binding oligomerization domain 2 (NOD2)-dependent autophagy
-
doi:10.1074/jbc.M111.326835
-
Homer CR, Kabi A, Marina-Garcia N, Sreekumar A, Nesvizhskii AI, Nickerson KP, et al. A dual role for receptor-interacting protein kinase 2 (RIP2) kinase activity in nucleotide-binding oligomerization domain 2 (NOD2)-dependent autophagy. J Biol Chem (2012) 287:25565-76. doi:10.1074/jbc.M111.326835
-
(2012)
J Biol Chem
, vol.287
, pp. 25565-25576
-
-
Homer, C.R.1
Kabi, A.2
Marina-Garcia, N.3
Sreekumar, A.4
Nesvizhskii, A.I.5
Nickerson, K.P.6
-
116
-
-
84887524897
-
The protein ATG16L1 suppresses inflammatory cytokines induced by the intracellular sensors Nod1 and Nod2 in an autophagy-independent manner
-
doi:10.1016/j.immuni.2013.10.013
-
Sorbara MT, Ellison LK, Ramjeet M, Travassos LH, Jones NL, Girardin SE, et al. The protein ATG16L1 suppresses inflammatory cytokines induced by the intracellular sensors Nod1 and Nod2 in an autophagy-independent manner. Immunity (2013) 39:858-73. doi:10.1016/j.immuni.2013.10.013
-
(2013)
Immunity
, vol.39
, pp. 858-873
-
-
Sorbara, M.T.1
Ellison, L.K.2
Ramjeet, M.3
Travassos, L.H.4
Jones, N.L.5
Girardin, S.E.6
-
117
-
-
84880256632
-
Impact of NOD2 polymorphisms on infectious complications following chemotherapy in patients with acute myeloid leukaemia
-
doi:10.1007/s00277-013-1734-0
-
Yomade O, Spies-Weisshart B, Glaser A, Schnetzke U, Hochhaus A, Scholl S. Impact of NOD2 polymorphisms on infectious complications following chemotherapy in patients with acute myeloid leukaemia. Ann Hematol (2013) 92:1071-7. doi:10.1007/s00277-013-1734-0
-
(2013)
Ann Hematol
, vol.92
, pp. 1071-1077
-
-
Yomade, O.1
Spies-Weisshart, B.2
Glaser, A.3
Schnetzke, U.4
Hochhaus, A.5
Scholl, S.6
-
118
-
-
77952557774
-
Association of c 802C >T polymorphism of NOD2/CARD15 gene with the chronic gastritis and predisposition to cancer in H pylori infected patients
-
doi:10.1016/j.yexmp.2010.03.003
-
Hnatyszyn A, Szalata M, Stanczyk J, Cichy W, Slomski R. Association of c.802C >T polymorphism of NOD2/CARD15 gene with the chronic gastritis and predisposition to cancer in H. pylori infected patients. Exp Mol Pathol (2010) 88:388-93. doi:10.1016/j.yexmp.2010.03.003
-
(2010)
Exp Mol Pathol
, vol.88
, pp. 388-393
-
-
Hnatyszyn, A.1
Szalata, M.2
Stanczyk, J.3
Cichy, W.4
Slomski, R.5
-
119
-
-
13644253821
-
The 3020insC allele of NOD2 predisposes to early-onset breast cancer
-
doi:10.1007/s10549-004-1250-y
-
Huzarski T, Lener M, Domagala W, Gronwald J, Byrski T, Kurzawski G, et al. The 3020insC allele of NOD2 predisposes to early-onset breast cancer. Breast Cancer Res Treat (2005) 89:91-3. doi:10.1007/s10549-004-1250-y
-
(2005)
Breast Cancer Res Treat
, vol.89
, pp. 91-93
-
-
Huzarski, T.1
Lener, M.2
Domagala, W.3
Gronwald, J.4
Byrski, T.5
Kurzawski, G.6
-
120
-
-
33645217871
-
Prevalence of the NOD2 3020insC mutation in aggregations of breast and lung cancer
-
doi:10.1007/s10549-005-9057-z
-
Lener MR, Oszutowska D, Castaneda J, Kurzawski G, Suchy J, Nej-Wolosiak K, et al. Prevalence of the NOD2 3020insC mutation in aggregations of breast and lung cancer. Breast Cancer Res Treat (2006) 95:141-5. doi:10.1007/s10549-005-9057-z
-
(2006)
Breast Cancer Res Treat
, vol.95
, pp. 141-145
-
-
Lener, M.R.1
Oszutowska, D.2
Castaneda, J.3
Kurzawski, G.4
Suchy, J.5
Nej-Wolosiak, K.6
-
121
-
-
77950526750
-
TLR4 and NOD2/CARD15 genetic polymorphisms and their possible role in gastric carcinogenesis
-
Rigoli L, Di Bella C, Fedele F, Procopio V, Amorini M, Lo Giudice G, et al. TLR4 and NOD2/CARD15 genetic polymorphisms and their possible role in gastric carcinogenesis. Anticancer Res (2010) 30:513-7.
-
(2010)
Anticancer Res
, vol.30
, pp. 513-517
-
-
Rigoli, L.1
Di Bella, C.2
Fedele, F.3
Procopio, V.4
Amorini, M.5
Lo Giudice, G.6
-
122
-
-
57749094105
-
The innate immune receptor Nod1 protects the intestine from inflammation-induced tumorigenesis
-
doi:10.1158/0008-5472.CAN-08-2061
-
Chen GY, Shaw MH, Redondo G, Nunez G. The innate immune receptor Nod1 protects the intestine from inflammation-induced tumorigenesis. Cancer Res (2008) 68:10060-7. doi:10.1158/0008-5472.CAN-08-2061
-
(2008)
Cancer Res
, vol.68
, pp. 10060-10067
-
-
Chen, G.Y.1
Shaw, M.H.2
Redondo, G.3
Nunez, G.4
-
123
-
-
0344237231
-
A novel inflammation-related mouse colon carcinogenesis model induced by azoxymethane and dextran sodium sulfate
-
doi:10.1111/j.1349-7006.2003.tb01386.x
-
Tanaka T, Kohno H, Suzuki R, Yamada Y, Sugie S, Mori H. A novel inflammation-related mouse colon carcinogenesis model induced by azoxymethane and dextran sodium sulfate. Cancer Sci (2003) 94:965-73. doi:10.1111/j.1349-7006.2003.tb01386.x
-
(2003)
Cancer Sci
, vol.94
, pp. 965-973
-
-
Tanaka, T.1
Kohno, H.2
Suzuki, R.3
Yamada, Y.4
Sugie, S.5
Mori, H.6
-
124
-
-
0025015168
-
A dominant mutation that predisposes to multiple intestinal neoplasia in the mouse
-
doi:10.1126/science.2296722
-
Moser AR, Pitot HC, Dove WF. A dominant mutation that predisposes to multiple intestinal neoplasia in the mouse. Science (1990) 247:322-4. doi:10.1126/science.2296722
-
(1990)
Science
, vol.247
, pp. 322-324
-
-
Moser, A.R.1
Pitot, H.C.2
Dove, W.F.3
-
125
-
-
0037404387
-
Colon carcinogenesis in inflammatory bowel disease: applying molecular genetics to clinical practice
-
doi:10.1097/00004836-200305001-00012
-
Itzkowitz S. Colon carcinogenesis in inflammatory bowel disease: applying molecular genetics to clinical practice. J Clin Gastroenterol (2003) 36:S70-4. doi:10.1097/00004836-200305001-00012
-
(2003)
J Clin Gastroenterol
, vol.36
-
-
Itzkowitz, S.1
-
126
-
-
44949256140
-
Mouse mutagenesis using N-Ethyl-N-nitrosourea (ENU)
-
doi:10.1101/pdb.prot4985
-
Salinger AP, Justice MJ. Mouse mutagenesis using N-Ethyl-N-nitrosourea (ENU). CSH Protoc (2008) 2008:pdb.prot4985. doi:10.1101/pdb.prot4985
-
(2008)
CSH Protoc
, vol.2008
-
-
Salinger, A.P.1
Justice, M.J.2
-
127
-
-
84890466847
-
Genes and SNPs associated with non-hereditary and hereditary colorectal cancer
-
doi:10.7314/APJCP.2013.14.10.5609
-
Nassiri M, Kooshyar MM, Roudbar Z, Mahdavi M, Doosti M. Genes and SNPs associated with non-hereditary and hereditary colorectal cancer. Asian Pac J Cancer Prev (2013) 14:5609-14. doi:10.7314/APJCP.2013.14.10.5609
-
(2013)
Asian Pac J Cancer Prev
, vol.14
, pp. 5609-5614
-
-
Nassiri, M.1
Kooshyar, M.M.2
Roudbar, Z.3
Mahdavi, M.4
Doosti, M.5
-
128
-
-
0033663048
-
Cytoplasmic beta-catenin accumulation as a predictor of hematogenous metastasis in human colorectal cancer
-
doi:10.1159/000012187
-
Maruyama K, Ochiai A, Akimoto S, Nakamura S, Baba S, Moriya Y, et al. Cytoplasmic beta-catenin accumulation as a predictor of hematogenous metastasis in human colorectal cancer. Oncology (2000) 59:302-9. doi:10.1159/000012187
-
(2000)
Oncology
, vol.59
, pp. 302-309
-
-
Maruyama, K.1
Ochiai, A.2
Akimoto, S.3
Nakamura, S.4
Baba, S.5
Moriya, Y.6
-
129
-
-
33751306998
-
Multistep carcinogenesis of the colon in Apc(Min/+) mouse
-
doi:10.1111/j.1349-7006.2006.00348.x
-
Yamada Y, Mori H. Multistep carcinogenesis of the colon in Apc(Min/+) mouse. Cancer Sci (2007) 98:6-10. doi:10.1111/j.1349-7006.2006.00348.x
-
(2007)
Cancer Sci
, vol.98
, pp. 6-10
-
-
Yamada, Y.1
Mori, H.2
-
130
-
-
84873372079
-
NOD2-mediated dysbiosis predisposes mice to transmissible colitis and colorectal cancer
-
doi:10.1172/JCI62236
-
Couturier-Maillard A, Secher T, Rehman A, Normand S, De Arcangelis A, Haesler R, et al. NOD2-mediated dysbiosis predisposes mice to transmissible colitis and colorectal cancer. J Clin Invest (2013) 123:700-11. doi:10.1172/JCI62236
-
(2013)
J Clin Invest
, vol.123
, pp. 700-711
-
-
Couturier-Maillard, A.1
Secher, T.2
Rehman, A.3
Normand, S.4
De Arcangelis, A.5
Haesler, R.6
-
131
-
-
84888882101
-
Nod-like receptors in head and neck squamous cell carcinoma
-
doi:10.3109/00016489.2013.831476
-
Millrud CR, Kvarnhammar AM, Tajti J, Munck-Wikland E, Uddman R, Cardell LO. Nod-like receptors in head and neck squamous cell carcinoma. Acta Otolaryngol (2013) 133:1333-44. doi:10.3109/00016489.2013.831476
-
(2013)
Acta Otolaryngol
, vol.133
, pp. 1333-1344
-
-
Millrud, C.R.1
Kvarnhammar, A.M.2
Tajti, J.3
Munck-Wikland, E.4
Uddman, R.5
Cardell, L.O.6
-
132
-
-
77950362382
-
The inflammasomes
-
doi:10.1016/j.cell.2010.01.040
-
Schroder K, Tschopp J. The inflammasomes. Cell (2010) 140:821-32. doi:10.1016/j.cell.2010.01.040
-
(2010)
Cell
, vol.140
, pp. 821-832
-
-
Schroder, K.1
Tschopp, J.2
-
133
-
-
0035179970
-
Mutation of a new gene encoding a putative pyrin-like protein causes familial cold autoinflammatory syndrome and Muckle-Wells syndrome
-
doi:10.1038/ng756
-
Hoffman HM, Mueller JL, Broide DH, Wanderer AA, Kolodner RD. Mutation of a new gene encoding a putative pyrin-like protein causes familial cold autoinflammatory syndrome and Muckle-Wells syndrome. Nat Genet (2001) 29:301-5. doi:10.1038/ng756
-
(2001)
Nat Genet
, vol.29
, pp. 301-305
-
-
Hoffman, H.M.1
Mueller, J.L.2
Broide, D.H.3
Wanderer, A.A.4
Kolodner, R.D.5
-
134
-
-
3142654767
-
Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf
-
doi:10.1038/nature02664
-
Mariathasan S, Newton K, Monack DM, Vucic D, French DM, Lee WP, et al. Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf. Nature (2004) 430:213-8. doi:10.1038/nature02664
-
(2004)
Nature
, vol.430
, pp. 213-218
-
-
Mariathasan, S.1
Newton, K.2
Monack, D.M.3
Vucic, D.4
French, D.M.5
Lee, W.P.6
-
135
-
-
33845890803
-
Inflammasome adaptors and sensors: intracellular regulators of infection and inflammation
-
doi:10.1038/nri1997
-
Mariathasan S, Monack DM. Inflammasome adaptors and sensors: intracellular regulators of infection and inflammation. Nat Rev Immunol (2007) 7:31-40. doi:10.1038/nri1997
-
(2007)
Nat Rev Immunol
, vol.7
, pp. 31-40
-
-
Mariathasan, S.1
Monack, D.M.2
-
136
-
-
1642285783
-
NALP3 forms an IL-1beta-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder
-
doi:10.1016/S1074-7613(04)00046-9
-
Agostini L, Martinon F, Burns K, Mcdermott MF, Hawkins PN, Tschopp J. NALP3 forms an IL-1beta-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder. Immunity (2004) 20:319-25. doi:10.1016/S1074-7613(04)00046-9
-
(2004)
Immunity
, vol.20
, pp. 319-325
-
-
Agostini, L.1
Martinon, F.2
Burns, K.3
Mcdermott, M.F.4
Hawkins, P.N.5
Tschopp, J.6
-
137
-
-
32944462834
-
Bacterial RNA and small antiviral compounds activate caspase-1 through cryopyrin/Nalp3
-
doi:10.1038/nature04517
-
Kanneganti TD, Ozoren N, Body-Malapel M, Amer A, Park JH, Franchi L, et al. Bacterial RNA and small antiviral compounds activate caspase-1 through cryopyrin/Nalp3. Nature (2006) 440:233-6. doi:10.1038/nature04517
-
(2006)
Nature
, vol.440
, pp. 233-236
-
-
Kanneganti, T.D.1
Ozoren, N.2
Body-Malapel, M.3
Amer, A.4
Park, J.H.5
Franchi, L.6
-
138
-
-
32944470765
-
Cryopyrin activates the inflammasome in response to toxins and ATP
-
doi:10.1038/nature04515
-
Mariathasan S, Weiss DS, Newton K, Mcbride J, O'Rourke K, Roose-Girma M, et al. Cryopyrin activates the inflammasome in response to toxins and ATP. Nature (2006) 440:228-32. doi:10.1038/nature04515
-
(2006)
Nature
, vol.440
, pp. 228-232
-
-
Mariathasan, S.1
Weiss, D.S.2
Newton, K.3
Mcbride, J.4
O'Rourke, K.5
Roose-Girma, M.6
-
139
-
-
32944468985
-
Gout-associated uric acid crystals activate the NALP3 inflammasome
-
doi:10.1038/nature04516
-
Martinon F, Petrilli V, Mayor A, Tardivel A, Tschopp J. Gout-associated uric acid crystals activate the NALP3 inflammasome. Nature (2006) 440:237-41. doi:10.1038/nature04516
-
(2006)
Nature
, vol.440
, pp. 237-241
-
-
Martinon, F.1
Petrilli, V.2
Mayor, A.3
Tardivel, A.4
Tschopp, J.5
-
140
-
-
33644985564
-
Critical role for NALP3/CIAS1/Cryopyrin in innate and adaptive immunity through its regulation of caspase-1
-
doi:10.1016/j.immuni.2006.02.004
-
Sutterwala FS, Ogura Y, Szczepanik M, Lara-Tejero M, Lichtenberger GS, Grant EP, et al. Critical role for NALP3/CIAS1/Cryopyrin in innate and adaptive immunity through its regulation of caspase-1. Immunity (2006) 24:317-27. doi:10.1016/j.immuni.2006.02.004
-
(2006)
Immunity
, vol.24
, pp. 317-327
-
-
Sutterwala, F.S.1
Ogura, Y.2
Szczepanik, M.3
Lara-Tejero, M.4
Lichtenberger, G.S.5
Grant, E.P.6
-
141
-
-
58449083290
-
Pyroptosis: host cell death and inflammation
-
doi:10.1038/nrmicro2070
-
Bergsbaken T, Fink SL, Cookson BT. Pyroptosis: host cell death and inflammation. Nat Rev Microbiol (2009) 7:99-109. doi:10.1038/nrmicro2070
-
(2009)
Nat Rev Microbiol
, vol.7
, pp. 99-109
-
-
Bergsbaken, T.1
Fink, S.L.2
Cookson, B.T.3
-
142
-
-
84876237736
-
The adaptor MAVS promotes NLRP3 mitochondrial localization and inflammasome activation
-
doi:10.1016/j.cell.2013.02.054
-
Subramanian N, Natarajan K, Clatworthy MR, Wang Z, Germain RN. The adaptor MAVS promotes NLRP3 mitochondrial localization and inflammasome activation. Cell (2013) 153:348-61. doi:10.1016/j.cell.2013.02.054
-
(2013)
Cell
, vol.153
, pp. 348-361
-
-
Subramanian, N.1
Natarajan, K.2
Clatworthy, M.R.3
Wang, Z.4
Germain, R.N.5
-
143
-
-
34247574122
-
Inflammasome components NALP 1 and 3 show distinct but separate expression profiles in human tissues suggesting a site-specific role in the inflammatory response
-
doi:10.1369/jhc.6A7101.2006
-
Kummer JA, Broekhuizen R, Everett H, Agostini L, Kuijk L, Martinon F, et al. Inflammasome components NALP 1 and 3 show distinct but separate expression profiles in human tissues suggesting a site-specific role in the inflammatory response. J Histochem Cytochem (2007) 55:443-52. doi:10.1369/jhc.6A7101.2006
-
(2007)
J Histochem Cytochem
, vol.55
, pp. 443-452
-
-
Kummer, J.A.1
Broekhuizen, R.2
Everett, H.3
Agostini, L.4
Kuijk, L.5
Martinon, F.6
-
144
-
-
79951818190
-
Differential expression of NLRP3 among hematopoietic cells
-
doi:10.4049/jimmunol.1002720
-
Guarda G, Zenger M, Yazdi AS, Schroder K, Ferrero I, Menu P, et al. Differential expression of NLRP3 among hematopoietic cells. J Immunol (2011) 186:2529-34. doi:10.4049/jimmunol.1002720
-
(2011)
J Immunol
, vol.186
, pp. 2529-2534
-
-
Guarda, G.1
Zenger, M.2
Yazdi, A.S.3
Schroder, K.4
Ferrero, I.5
Menu, P.6
-
145
-
-
79953046719
-
The inflammasome NLRs in immunity, inflammation, and associated diseases
-
doi:10.1146/annurev-immunol-031210-101405
-
Davis BK, Wen H, Ting JP. The inflammasome NLRs in immunity, inflammation, and associated diseases. Annu Rev Immunol (2011) 29:707-35. doi:10.1146/annurev-immunol-031210-101405
-
(2011)
Annu Rev Immunol
, vol.29
, pp. 707-735
-
-
Davis, B.K.1
Wen, H.2
Ting, J.P.3
-
146
-
-
84869504451
-
Inflammasomes and their roles in health and disease
-
doi:10.1146/annurev-cellbio-101011-155745
-
Lamkanfi M, Dixit VM. Inflammasomes and their roles in health and disease. Annu Rev Cell Dev Biol (2012) 28:137-61. doi:10.1146/annurev-cellbio-101011-155745
-
(2012)
Annu Rev Cell Dev Biol
, vol.28
, pp. 137-161
-
-
Lamkanfi, M.1
Dixit, V.M.2
-
147
-
-
84874211596
-
Intestinal antimicrobial peptides during homeostasis, infection, and disease
-
doi:10.3389/fimmu.2012.00310
-
Muniz LR, Knosp C, Yeretssian G. Intestinal antimicrobial peptides during homeostasis, infection, and disease. Front Immunol (2012) 3:310. doi:10.3389/fimmu.2012.00310
-
(2012)
Front Immunol
, vol.3
, pp. 310
-
-
Muniz, L.R.1
Knosp, C.2
Yeretssian, G.3
-
148
-
-
84878237993
-
Activation and regulation of the inflammasomes
-
doi:10.1038/nri3452
-
Latz E, Xiao TS, Stutz A. Activation and regulation of the inflammasomes. Nat Rev Immunol (2013) 13:397-411. doi:10.1038/nri3452
-
(2013)
Nat Rev Immunol
, vol.13
, pp. 397-411
-
-
Latz, E.1
Xiao, T.S.2
Stutz, A.3
-
149
-
-
70249138036
-
Cutting edge: NF-kappaB activating pattern recognition and cytokine receptors license NLRP3 inflammasome activation by regulating NLRP3 expression
-
doi:10.4049/jimmunol.0901363
-
Bauernfeind FG, Horvath G, Stutz A, Alnemri ES, Macdonald K, Speert D, et al. Cutting edge: NF-kappaB activating pattern recognition and cytokine receptors license NLRP3 inflammasome activation by regulating NLRP3 expression. J Immunol (2009) 183:787-91. doi:10.4049/jimmunol.0901363
-
(2009)
J Immunol
, vol.183
, pp. 787-791
-
-
Bauernfeind, F.G.1
Horvath, G.2
Stutz, A.3
Alnemri, E.S.4
Macdonald, K.5
Speert, D.6
-
150
-
-
84898635026
-
Inflammasome priming by lipopolysaccharide is dependent upon ERK signaling and proteasome function
-
doi:10.4049/jimmunol.1301974
-
Ghonime MG, Shamaa OR, Das S, Eldomany RA, Fernandes-Alnemri T, Alnemri ES, et al. Inflammasome priming by lipopolysaccharide is dependent upon ERK signaling and proteasome function. J Immunol (2014) 192:3881-8. doi:10.4049/jimmunol.1301974
-
(2014)
J Immunol
, vol.192
, pp. 3881-3888
-
-
Ghonime, M.G.1
Shamaa, O.R.2
Das, S.3
Eldomany, R.A.4
Fernandes-Alnemri, T.5
Alnemri, E.S.6
-
151
-
-
0031973493
-
Lipopolysaccharide activates caspase-1 (interleukin-1-converting enzyme) in cultured monocytic and endothelial cells
-
Schumann RR, Belka C, Reuter D, Lamping N, Kirschning CJ, Weber JR, et al. Lipopolysaccharide activates caspase-1 (interleukin-1-converting enzyme) in cultured monocytic and endothelial cells. Blood (1998) 91:577-84.
-
(1998)
Blood
, vol.91
, pp. 577-584
-
-
Schumann, R.R.1
Belka, C.2
Reuter, D.3
Lamping, N.4
Kirschning, C.J.5
Weber, J.R.6
-
152
-
-
64049084303
-
Differential requirement for the activation of the inflammasome for processing and release of IL-1beta in monocytes and macrophages
-
doi:10.1182/blood-2008-03-146720
-
Netea MG, Nold-Petry CA, Nold MF, Joosten LA, Opitz B, Van Der Meer JH, et al. Differential requirement for the activation of the inflammasome for processing and release of IL-1beta in monocytes and macrophages. Blood (2009) 113:2324-35. doi:10.1182/blood-2008-03-146720
-
(2009)
Blood
, vol.113
, pp. 2324-2335
-
-
Netea, M.G.1
Nold-Petry, C.A.2
Nold, M.F.3
Joosten, L.A.4
Opitz, B.5
Van Der Meer, J.H.6
-
153
-
-
79960542894
-
Cutting edge: reactive oxygen species inhibitors block priming, but not activation, of the NLRP3 inflammasome
-
doi:10.4049/jimmunol.1100613
-
Bauernfeind F, Bartok E, Rieger A, Franchi L, Nunez G, Hornung V. Cutting edge: reactive oxygen species inhibitors block priming, but not activation, of the NLRP3 inflammasome. J Immunol (2011) 187:613-7. doi:10.4049/jimmunol.1100613
-
(2011)
J Immunol
, vol.187
, pp. 613-617
-
-
Bauernfeind, F.1
Bartok, E.2
Rieger, A.3
Franchi, L.4
Nunez, G.5
Hornung, V.6
-
154
-
-
84867770402
-
Non-transcriptional priming and deubiquitination regulate NLRP3 inflammasome activation
-
doi:10.1074/jbc.M112.407130
-
Juliana C, Fernandes-Alnemri T, Kang S, Farias A, Qin F, Alnemri ES. Non-transcriptional priming and deubiquitination regulate NLRP3 inflammasome activation. J Biol Chem (2012) 287:36617-22. doi:10.1074/jbc.M112.407130
-
(2012)
J Biol Chem
, vol.287
, pp. 36617-36622
-
-
Juliana, C.1
Fernandes-Alnemri, T.2
Kang, S.3
Farias, A.4
Qin, F.5
Alnemri, E.S.6
-
155
-
-
70449360107
-
Staphylococcus aureus alpha-hemolysin activates the NLRP3-inflammasome in human and mouse monocytic cells
-
doi:10.1371/journal.pone.0007446
-
Craven RR, Gao X, Allen IC, Gris D, Bubeck Wardenburg J, Mcelvania-Tekippe E, et al. Staphylococcus aureus alpha-hemolysin activates the NLRP3-inflammasome in human and mouse monocytic cells. PLoS One (2009) 4:e7446. doi:10.1371/journal.pone.0007446
-
(2009)
PLoS One
, vol.4
-
-
Craven, R.R.1
Gao, X.2
Allen, I.C.3
Gris, D.4
Bubeck Wardenburg, J.5
Mcelvania-Tekippe, E.6
-
156
-
-
79251515144
-
Pneumolysin activates the NLRP3 inflammasome and promotes proinflammatory cytokines independently of TLR4
-
doi:10.1371/journal.ppat.1001191
-
McNeela EA, Burke A, Neill DR, Baxter C, Fernandes VE, Ferreira D, et al. Pneumolysin activates the NLRP3 inflammasome and promotes proinflammatory cytokines independently of TLR4. PLoS Pathog (2010) 6:e1001191. doi:10.1371/journal.ppat.1001191
-
(2010)
PLoS Pathog
, vol.6
-
-
McNeela, E.A.1
Burke, A.2
Neill, D.R.3
Baxter, C.4
Fernandes, V.E.5
Ferreira, D.6
-
157
-
-
33846014297
-
Critical role for Cryopyrin/Nalp3 in activation of caspase-1 in response to viral infection and double-stranded RNA
-
doi:10.1074/jbc.M607594200
-
Kanneganti TD, Body-Malapel M, Amer A, Park JH, Whitfield J, Franchi L, et al. Critical role for Cryopyrin/Nalp3 in activation of caspase-1 in response to viral infection and double-stranded RNA. J Biol Chem (2006) 281:36560-8. doi:10.1074/jbc.M607594200
-
(2006)
J Biol Chem
, vol.281
, pp. 36560-36568
-
-
Kanneganti, T.D.1
Body-Malapel, M.2
Amer, A.3
Park, J.H.4
Whitfield, J.5
Franchi, L.6
-
158
-
-
64049111768
-
The NLRP3 inflammasome mediates in vivo innate immunity to influenza A virus through recognition of viral RNA
-
doi:10.1016/j.immuni.2009.02.005
-
Allen IC, Scull MA, Moore CB, Holl EK, Mcelvania-Tekippe E, Taxman DJ, et al. The NLRP3 inflammasome mediates in vivo innate immunity to influenza A virus through recognition of viral RNA. Immunity (2009) 30:556-65. doi:10.1016/j.immuni.2009.02.005
-
(2009)
Immunity
, vol.30
, pp. 556-565
-
-
Allen, I.C.1
Scull, M.A.2
Moore, C.B.3
Holl, E.K.4
Mcelvania-Tekippe, E.5
Taxman, D.J.6
-
159
-
-
64049096334
-
The intracellular sensor NLRP3 mediates key innate and healing responses to influenza A virus via the regulation of caspase-1
-
doi:10.1016/j.immuni.2009.02.006
-
Thomas PG, Dash P, Aldridge JR Jr., Ellebedy AH, Reynolds C, Funk AJ, et al. The intracellular sensor NLRP3 mediates key innate and healing responses to influenza A virus via the regulation of caspase-1. Immunity (2009) 30:566-75. doi:10.1016/j.immuni.2009.02.006
-
(2009)
Immunity
, vol.30
, pp. 566-575
-
-
Thomas, P.G.1
Dash, P.2
Aldridge Jr., J.R.3
Ellebedy, A.H.4
Reynolds, C.5
Funk, A.J.6
-
160
-
-
78249269470
-
Activation of the NLRP3 inflammasome by intracellular poly I:C
-
doi:10.1016/j.febslet.2010.10.036
-
Rajan JV, Warren SE, Miao EA, Aderem A. Activation of the NLRP3 inflammasome by intracellular poly I:C. FEBS Lett (2010) 584:4627-32. doi:10.1016/j.febslet.2010.10.036
-
(2010)
FEBS Lett
, vol.584
, pp. 4627-4632
-
-
Rajan, J.V.1
Warren, S.E.2
Miao, E.A.3
Aderem, A.4
-
161
-
-
34247118826
-
Pannexin-1-mediated recognition of bacterial molecules activates the cryopyrin inflammasome independent of Toll-like receptor signaling
-
doi:10.1016/j.immuni.2007.03.008
-
Kanneganti TD, Lamkanfi M, Kim YG, Chen G, Park JH, Franchi L, et al. Pannexin-1-mediated recognition of bacterial molecules activates the cryopyrin inflammasome independent of Toll-like receptor signaling. Immunity (2007) 26:433-43. doi:10.1016/j.immuni.2007.03.008
-
(2007)
Immunity
, vol.26
, pp. 433-443
-
-
Kanneganti, T.D.1
Lamkanfi, M.2
Kim, Y.G.3
Chen, G.4
Park, J.H.5
Franchi, L.6
-
162
-
-
45849102043
-
ATP is released by monocytes stimulated with pathogen-sensing receptor ligands and induces IL-1beta and IL-18 secretion in an autocrine way
-
doi:10.1073/pnas.0709684105
-
Piccini A, Carta S, Tassi S, Lasiglie D, Fossati G, Rubartelli A. ATP is released by monocytes stimulated with pathogen-sensing receptor ligands and induces IL-1beta and IL-18 secretion in an autocrine way. Proc Natl Acad Sci U S A (2008) 105:8067-72. doi:10.1073/pnas.0709684105
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 8067-8072
-
-
Piccini, A.1
Carta, S.2
Tassi, S.3
Lasiglie, D.4
Fossati, G.5
Rubartelli, A.6
-
163
-
-
84874280249
-
ATP release and purinergic signaling in NLRP3 inflammasome activation
-
doi:10.3389/fimmu.2012.00414
-
Gombault A, Baron L, Couillin I. ATP release and purinergic signaling in NLRP3 inflammasome activation. Front Immunol (2012) 3:414. doi:10.3389/fimmu.2012.00414
-
(2012)
Front Immunol
, vol.3
, pp. 414
-
-
Gombault, A.1
Baron, L.2
Couillin, I.3
-
164
-
-
84863103053
-
ATP release from dying autophagic cells and their phagocytosis are crucial for inflammasome activation in macrophages
-
doi:10.1371/journal.pone.0040069
-
Ayna G, Krysko DV, Kaczmarek A, Petrovski G, Vandenabeele P, Fesus L. ATP release from dying autophagic cells and their phagocytosis are crucial for inflammasome activation in macrophages. PLoS One (2012) 7:e40069. doi:10.1371/journal.pone.0040069
-
(2012)
PLoS One
, vol.7
-
-
Ayna, G.1
Krysko, D.V.2
Kaczmarek, A.3
Petrovski, G.4
Vandenabeele, P.5
Fesus, L.6
-
165
-
-
47849132947
-
The Nalp3 inflammasome is essential for the development of silicosis
-
doi:10.1073/pnas.0803933105
-
Cassel SL, Eisenbarth SC, Iyer SS, Sadler JJ, Colegio OR, Tephly LA, et al. The Nalp3 inflammasome is essential for the development of silicosis. Proc Natl Acad Sci U S A (2008) 105:9035-40. doi:10.1073/pnas.0803933105
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 9035-9040
-
-
Cassel, S.L.1
Eisenbarth, S.C.2
Iyer, S.S.3
Sadler, J.J.4
Colegio, O.R.5
Tephly, L.A.6
-
166
-
-
43249125839
-
Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica
-
doi:10.1126/science.1156995
-
Dostert C, Petrilli V, Van Bruggen R, Steele C, Mossman BT, Tschopp J. Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica. Science (2008) 320:674-7. doi:10.1126/science.1156995
-
(2008)
Science
, vol.320
, pp. 674-677
-
-
Dostert, C.1
Petrilli, V.2
Van Bruggen, R.3
Steele, C.4
Mossman, B.T.5
Tschopp, J.6
-
167
-
-
45749111446
-
Crucial role for the Nalp3 inflammasome in the immunostimulatory properties of aluminium adjuvants
-
doi:10.1038/nature06939
-
Eisenbarth SC, Colegio OR, O'Connor W, Sutterwala FS, Flavell RA. Crucial role for the Nalp3 inflammasome in the immunostimulatory properties of aluminium adjuvants. Nature (2008) 453:1122-6. doi:10.1038/nature06939
-
(2008)
Nature
, vol.453
, pp. 1122-1126
-
-
Eisenbarth, S.C.1
Colegio, O.R.2
O'Connor, W.3
Sutterwala, F.S.4
Flavell, R.A.5
-
168
-
-
47849085872
-
The NALP3 inflammasome is involved in the innate immune response to amyloid-beta
-
doi:10.1038/ni.1636
-
Halle A, Hornung V, Petzold GC, Stewart CR, Monks BG, Reinheckel T, et al. The NALP3 inflammasome is involved in the innate immune response to amyloid-beta. Nat Immunol (2008) 9:857-65. doi:10.1038/ni.1636
-
(2008)
Nat Immunol
, vol.9
, pp. 857-865
-
-
Halle, A.1
Hornung, V.2
Petzold, G.C.3
Stewart, C.R.4
Monks, B.G.5
Reinheckel, T.6
-
169
-
-
47849097202
-
Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization
-
doi:10.1038/ni.1631
-
Hornung V, Bauernfeind F, Halle A, Samstad EO, Kono H, Rock KL, et al. Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization. Nat Immunol (2008) 9:847-56. doi:10.1038/ni.1631
-
(2008)
Nat Immunol
, vol.9
, pp. 847-856
-
-
Hornung, V.1
Bauernfeind, F.2
Halle, A.3
Samstad, E.O.4
Kono, H.5
Rock, K.L.6
-
170
-
-
79952950889
-
The role of the NLRP3 inflammasome in gout
-
doi:10.2147/JIR.S11330
-
Kingsbury SR, Conaghan PG, Mcdermott MF. The role of the NLRP3 inflammasome in gout. J Inflamm Res (2011) 4:39-49. doi:10.2147/JIR.S11330
-
(2011)
J Inflamm Res
, vol.4
, pp. 39-49
-
-
Kingsbury, S.R.1
Conaghan, P.G.2
Mcdermott, M.F.3
-
171
-
-
68349157477
-
Malarial hemozoin is a Nalp3 inflammasome activating danger signal
-
doi:10.1371/journal.pone.0006510
-
Dostert C, Guarda G, Romero JF, Menu P, Gross O, Tardivel A, et al. Malarial hemozoin is a Nalp3 inflammasome activating danger signal. PLoS One (2009) 4:e6510. doi:10.1371/journal.pone.0006510
-
(2009)
PLoS One
, vol.4
-
-
Dostert, C.1
Guarda, G.2
Romero, J.F.3
Menu, P.4
Gross, O.5
Tardivel, A.6
-
172
-
-
79951642032
-
Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome
-
doi:10.1038/ni.1980
-
Nakahira K, Haspel JA, Rathinam VA, Lee SJ, Dolinay T, Lam HC, et al. Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome. Nat Immunol (2011) 12:222-30. doi:10.1038/ni.1980
-
(2011)
Nat Immunol
, vol.12
, pp. 222-230
-
-
Nakahira, K.1
Haspel, J.A.2
Rathinam, V.A.3
Lee, S.J.4
Dolinay, T.5
Lam, H.C.6
-
173
-
-
78651393239
-
A role for mitochondria in NLRP3 inflammasome activation
-
doi:10.1038/nature09663
-
Zhou R, Yazdi AS, Menu P, Tschopp J. A role for mitochondria in NLRP3 inflammasome activation. Nature (2011) 469:221-5. doi:10.1038/nature09663
-
(2011)
Nature
, vol.469
, pp. 221-225
-
-
Zhou, R.1
Yazdi, A.S.2
Menu, P.3
Tschopp, J.4
-
174
-
-
84862777872
-
Oxidized mitochondrial DNA activates the NLRP3 inflammasome during apoptosis
-
doi:10.1016/j.immuni.2012.01.009
-
Shimada K, Crother TR, Karlin J, Dagvadorj J, Chiba N, Chen S, et al. Oxidized mitochondrial DNA activates the NLRP3 inflammasome during apoptosis. Immunity (2012) 36:401-14. doi:10.1016/j.immuni.2012.01.009
-
(2012)
Immunity
, vol.36
, pp. 401-414
-
-
Shimada, K.1
Crother, T.R.2
Karlin, J.3
Dagvadorj, J.4
Chiba, N.5
Chen, S.6
-
175
-
-
84875908991
-
TRPM2 links oxidative stress to NLRP3 inflammasome activation
-
doi:10.1038/ncomms2608
-
Zhong Z, Zhai Y, Liang S, Mori Y, Han R, Sutterwala FS, et al. TRPM2 links oxidative stress to NLRP3 inflammasome activation. Nat Commun (2013) 4:1611. doi:10.1038/ncomms2608
-
(2013)
Nat Commun
, vol.4
, pp. 1611
-
-
Zhong, Z.1
Zhai, Y.2
Liang, S.3
Mori, Y.4
Han, R.5
Sutterwala, F.S.6
-
176
-
-
84882614243
-
Mitochondrial cardiolipin is required for Nlrp3 inflammasome activation
-
doi:10.1016/j.immuni.2013.08.001
-
Iyer SS, He Q, Janczy JR, Elliott EI, Zhong Z, Olivier AK, et al. Mitochondrial cardiolipin is required for Nlrp3 inflammasome activation. Immunity (2013) 39:311-23. doi:10.1016/j.immuni.2013.08.001
-
(2013)
Immunity
, vol.39
, pp. 311-323
-
-
Iyer, S.S.1
He, Q.2
Janczy, J.R.3
Elliott, E.I.4
Zhong, Z.5
Olivier, A.K.6
-
177
-
-
84870508924
-
The calcium-sensing receptor regulates the NLRP3 inflammasome through Ca2+ and cAMP
-
doi:10.1038/nature11588
-
Lee GS, Subramanian N, Kim AI, Aksentijevich I, Goldbach-Mansky R, Sacks DB, et al. The calcium-sensing receptor regulates the NLRP3 inflammasome through Ca2+ and cAMP. Nature (2012) 492:123-7. doi:10.1038/nature11588
-
(2012)
Nature
, vol.492
, pp. 123-127
-
-
Lee, G.S.1
Subramanian, N.2
Kim, A.I.3
Aksentijevich, I.4
Goldbach-Mansky, R.5
Sacks, D.B.6
-
178
-
-
84863978096
-
Critical role for calcium mobilization in activation of the NLRP3 inflammasome
-
doi:10.1073/pnas.1117765109
-
Murakami T, Ockinger J, Yu J, Byles V, Mccoll A, Hofer AM, et al. Critical role for calcium mobilization in activation of the NLRP3 inflammasome. Proc Natl Acad Sci U S A (2012) 109:11282-7. doi:10.1073/pnas.1117765109
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
, pp. 11282-11287
-
-
Murakami, T.1
Ockinger, J.2
Yu, J.3
Byles, V.4
Mccoll, A.5
Hofer, A.M.6
-
179
-
-
84871797522
-
Extracellular Ca2+ is a danger signal activating the NLRP3 inflammasome through G protein-coupled calcium sensing receptors
-
doi:10.1038/ncomms2339
-
Rossol M, Pierer M, Raulien N, Quandt D, Meusch U, Rothe K, et al. Extracellular Ca2+ is a danger signal activating the NLRP3 inflammasome through G protein-coupled calcium sensing receptors. Nat Commun (2012) 3:1329. doi:10.1038/ncomms2339
-
(2012)
Nat Commun
, vol.3
, pp. 1329
-
-
Rossol, M.1
Pierer, M.2
Raulien, N.3
Quandt, D.4
Meusch, U.5
Rothe, K.6
-
180
-
-
84860225554
-
-
doi:10.1126/science.1217141
-
Shenoy AR, Wellington DA, Kumar P, Kassa H, Booth CJ, Cresswell P, et al. GBP5 promotes NLRP3 inflammasome assembly and immunity in mammals. Science (2012) 336:481-5. doi:10.1126/science.1217141
-
(2012)
Science
, vol.336
, pp. 481-485
-
-
Shenoy, A.R.1
Wellington, D.A.2
Kumar, P.3
Kassa, H.4
Booth, C.J.5
Cresswell, P.6
-
181
-
-
84879596906
-
K(+) efflux is the common trigger of NLRP3 inflammasome activation by bacterial toxins and particulate matter
-
doi:10.1016/j.immuni.2013.05.016
-
Munoz-Planillo R, Kuffa P, Martinez-Colon G, Smith BL, Rajendiran TM, Nunez G. K(+) efflux is the common trigger of NLRP3 inflammasome activation by bacterial toxins and particulate matter. Immunity (2013) 38:1142-53. doi:10.1016/j.immuni.2013.05.016
-
(2013)
Immunity
, vol.38
, pp. 1142-1153
-
-
Munoz-Planillo, R.1
Kuffa, P.2
Martinez-Colon, G.3
Smith, B.L.4
Rajendiran, T.M.5
Nunez, G.6
-
182
-
-
56249090667
-
Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1beta production
-
doi:10.1038/nature07383
-
Saitoh T, Fujita N, Jang MH, Uematsu S, Yang BG, Satoh T, et al. Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1beta production. Nature (2008) 456:264-8. doi:10.1038/nature07383
-
(2008)
Nature
, vol.456
, pp. 264-268
-
-
Saitoh, T.1
Fujita, N.2
Jang, M.H.3
Uematsu, S.4
Yang, B.G.5
Satoh, T.6
-
183
-
-
79953176280
-
Autophagy controls IL-1beta secretion by targeting pro-IL-1beta for degradation
-
doi:10.1074/jbc.M110.202911
-
Harris J, Hartman M, Roche C, Zeng SG, O'Shea A, Sharp FA, et al. Autophagy controls IL-1beta secretion by targeting pro-IL-1beta for degradation. J Biol Chem (2011) 286:9587-97. doi:10.1074/jbc.M110.202911
-
(2011)
J Biol Chem
, vol.286
, pp. 9587-9597
-
-
Harris, J.1
Hartman, M.2
Roche, C.3
Zeng, S.G.4
O'Shea, A.5
Sharp, F.A.6
-
184
-
-
84857195479
-
Activation of autophagy by inflammatory signals limits IL-1beta production by targeting ubiquitinated inflammasomes for destruction
-
doi:10.1038/ni.2215
-
Shi CS, Shenderov K, Huang NN, Kabat J, Abu-Asab M, Fitzgerald KA, et al. Activation of autophagy by inflammatory signals limits IL-1beta production by targeting ubiquitinated inflammasomes for destruction. Nat Immunol (2012) 13:255-63. doi:10.1038/ni.2215
-
(2012)
Nat Immunol
, vol.13
, pp. 255-263
-
-
Shi, C.S.1
Shenderov, K.2
Huang, N.N.3
Kabat, J.4
Abu-Asab, M.5
Fitzgerald, K.A.6
-
185
-
-
84876685141
-
Receptor interacting protein kinase 2-mediated mitophagy regulates inflammasome activation during virus infection
-
doi:10.1038/ni.2563
-
Lupfer C, Thomas PG, Anand PK, Vogel P, Milasta S, Martinez J, et al. Receptor interacting protein kinase 2-mediated mitophagy regulates inflammasome activation during virus infection. Nat Immunol (2013) 14:480-8. doi:10.1038/ni.2563
-
(2013)
Nat Immunol
, vol.14
, pp. 480-488
-
-
Lupfer, C.1
Thomas, P.G.2
Anand, P.K.3
Vogel, P.4
Milasta, S.5
Martinez, J.6
-
186
-
-
33947717153
-
Bcl-2 and Bcl-XL regulate proinflammatory caspase-1 activation by interaction with NALP1
-
doi:10.1016/j.cell.2007.01.045
-
Bruey JM, Bruey-Sedano N, Luciano F, Zhai D, Balpai R, Xu C, et al. Bcl-2 and Bcl-XL regulate proinflammatory caspase-1 activation by interaction with NALP1. Cell (2007) 129:45-56. doi:10.1016/j.cell.2007.01.045
-
(2007)
Cell
, vol.129
, pp. 45-56
-
-
Bruey, J.M.1
Bruey-Sedano, N.2
Luciano, F.3
Zhai, D.4
Balpai, R.5
Xu, C.6
-
187
-
-
62649092113
-
Mechanism of Bcl-2 and Bcl-X(L) inhibition of NLRP1 inflammasome: loop domain-dependent suppression of ATP binding and oligomerization
-
doi:10.1073/pnas.0809414106
-
Faustin B, Chen Y, Zhai D, Le Negrate G, Lartigue L, Satterthwait A, et al. Mechanism of Bcl-2 and Bcl-X(L) inhibition of NLRP1 inflammasome: loop domain-dependent suppression of ATP binding and oligomerization. Proc Natl Acad Sci U S A (2009) 106:3935-40. doi:10.1073/pnas.0809414106
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 3935-3940
-
-
Faustin, B.1
Chen, Y.2
Zhai, D.3
Le Negrate, G.4
Lartigue, L.5
Satterthwait, A.6
-
188
-
-
0030447149
-
Inhibition of interleukin 1 beta-converting enzyme-mediated apoptosis of mammalian cells by baculovirus IAP
-
doi:10.1073/pnas.93.24.13786
-
Hawkins CJ, Uren AG, Hacker G, Medcalf RL, Vaux DL. Inhibition of interleukin 1 beta-converting enzyme-mediated apoptosis of mammalian cells by baculovirus IAP. Proc Natl Acad Sci U S A (1996) 93:13786-90. doi:10.1073/pnas.93.24.13786
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, pp. 13786-13790
-
-
Hawkins, C.J.1
Uren, A.G.2
Hacker, G.3
Medcalf, R.L.4
Vaux, D.L.5
-
189
-
-
84255178199
-
Cellular inhibitors of apoptosis proteins cIAP1 and cIAP2 are required for efficient caspase-1 activation by the inflammasome
-
DoironK, Leblanc PM, Saleh M.
-
Labbe K, Mcintire CR, Doiron K, Leblanc PM, Saleh M. Cellular inhibitors of apoptosis proteins cIAP1 and cIAP2 are required for efficient caspase-1 activation by the inflammasome. Immunity (2011) 35:897-907. doi:10.1016/j.immuni.2011.10.016
-
(2011)
Immunity
, vol.35
, pp. 897-907
-
-
Labbe, K.1
Mcintire, C.R.2
-
190
-
-
84857404572
-
Inhibitor of apoptosis proteins limit RIP3 kinase-dependent interleukin-1 activation
-
doi:10.1016/j.immuni.2012.01.012
-
Vince JE, Wong WW, Gentle I, Lawlor KE, Allam R, O'Reilly L, et al. Inhibitor of apoptosis proteins limit RIP3 kinase-dependent interleukin-1 activation. Immunity (2012) 36:215-27. doi:10.1016/j.immuni.2012.01.012
-
(2012)
Immunity
, vol.36
, pp. 215-227
-
-
Vince, J.E.1
Wong, W.W.2
Gentle, I.3
Lawlor, K.E.4
Allam, R.5
O'Reilly, L.6
-
191
-
-
80455176839
-
Non-canonical inflammasome activation targets caspase-11
-
doi:10.1038/nature10558
-
Kayagaki N, Warming S, Lamkanfi M, Vande Walle L, Louie S, Dong J, et al. Non-canonical inflammasome activation targets caspase-11. Nature (2011) 479:117-21. doi:10.1038/nature10558
-
(2011)
Nature
, vol.479
, pp. 117-121
-
-
Kayagaki, N.1
Warming, S.2
Lamkanfi, M.3
Vande Walle, L.4
Louie, S.5
Dong, J.6
-
192
-
-
84867241369
-
Toll or interleukin-1 receptor (TIR) domain-containing adaptor inducing interferon-beta (TRIF)-mediated caspase-11 protease production integrates Toll-like receptor 4 (TLR4) protein- and Nlrp3 inflammasome-mediated host defense against enteropathogens
-
doi:10.1074/jbc.M112.401406
-
Gurung P, Malireddi RK, Anand PK, Demon D, Vande Walle L, Liu Z, et al. Toll or interleukin-1 receptor (TIR) domain-containing adaptor inducing interferon-beta (TRIF)-mediated caspase-11 protease production integrates Toll-like receptor 4 (TLR4) protein- and Nlrp3 inflammasome-mediated host defense against enteropathogens. J Biol Chem (2012) 287:34474-83. doi:10.1074/jbc.M112.401406
-
(2012)
J Biol Chem
, vol.287
, pp. 34474-34483
-
-
Gurung, P.1
Malireddi, R.K.2
Anand, P.K.3
Demon, D.4
Vande Walle, L.5
Liu, Z.6
-
193
-
-
84864600268
-
TRIF licenses caspase-11-dependent NLRP3 inflammasome activation by gram-negative bacteria
-
doi:10.1016/j.cell.2012.07.007
-
Rathinam VA, Vanaja SK, Waggoner L, Sokolovska A, Becker C, Stuart LM, et al. TRIF licenses caspase-11-dependent NLRP3 inflammasome activation by gram-negative bacteria. Cell (2012) 150:606-19. doi:10.1016/j.cell.2012.07.007
-
(2012)
Cell
, vol.150
, pp. 606-619
-
-
Rathinam, V.A.1
Vanaja, S.K.2
Waggoner, L.3
Sokolovska, A.4
Becker, C.5
Stuart, L.M.6
-
194
-
-
84882280029
-
AIM2 and NLRP3 inflammasomes activate both apoptotic and pyroptotic death pathways via ASC
-
doi:10.1038/cdd.2013.37
-
Sagulenko V, Thygesen SJ, Sester DP, Idris A, Cridland JA, Vajjhala PR, et al. AIM2 and NLRP3 inflammasomes activate both apoptotic and pyroptotic death pathways via ASC. Cell Death Differ (2013) 20:1149-60. doi:10.1038/cdd.2013.37
-
(2013)
Cell Death Differ
, vol.20
, pp. 1149-1160
-
-
Sagulenko, V.1
Thygesen, S.J.2
Sester, D.P.3
Idris, A.4
Cridland, J.A.5
Vajjhala, P.R.6
-
195
-
-
84894271641
-
FADD and caspase-8 mediate priming and activation of the canonical and noncanonical Nlrp3 inflammasomes
-
doi:10.4049/jimmunol.1302839
-
Gurung P, Anand PK, Malireddi RK, Vande Walle L, Van Opdenbosch N, Dillon CP, et al. FADD and caspase-8 mediate priming and activation of the canonical and noncanonical Nlrp3 inflammasomes. J Immunol (2014) 192:1835-46. doi:10.4049/jimmunol.1302839
-
(2014)
J Immunol
, vol.192
, pp. 1835-1846
-
-
Gurung, P.1
Anand, P.K.2
Malireddi, R.K.3
Vande Walle, L.4
Van Opdenbosch, N.5
Dillon, C.P.6
-
196
-
-
84872764927
-
Caspase-8 blocks kinase RIPK3-mediated activation of the NLRP3 inflammasome
-
doi:10.1016/j.immuni.2012.09.015
-
Kang TB, Yang SH, Toth B, Kovalenko A, Wallach D. Caspase-8 blocks kinase RIPK3-mediated activation of the NLRP3 inflammasome. Immunity (2013) 38:27-40. doi:10.1016/j.immuni.2012.09.015
-
(2013)
Immunity
, vol.38
, pp. 27-40
-
-
Kang, T.B.1
Yang, S.H.2
Toth, B.3
Kovalenko, A.4
Wallach, D.5
-
197
-
-
77952303410
-
The NLRP3 inflammasome functions as a negative regulator of tumorigenesis during colitis-associated cancer
-
doi:10.1084/jem.20100050
-
Allen IC, Tekippe EM, Woodford RM, Uronis JM, Holl EK, Rogers AB, et al. The NLRP3 inflammasome functions as a negative regulator of tumorigenesis during colitis-associated cancer. J Exp Med (2010) 207:1045-56. doi:10.1084/jem.20100050
-
(2010)
J Exp Med
, vol.207
, pp. 1045-1056
-
-
Allen, I.C.1
Tekippe, E.M.2
Woodford, R.M.3
Uronis, J.M.4
Holl, E.K.5
Rogers, A.B.6
-
198
-
-
77950002937
-
The NLRP3 inflammasome protects against loss of epithelial integrity and mortality during experimental colitis
-
doi:10.1016/j.immuni.2010.03.003
-
Zaki MH, Boyd KL, Vogel P, Kastan MB, Lamkanfi M, Kanneganti TD. The NLRP3 inflammasome protects against loss of epithelial integrity and mortality during experimental colitis. Immunity (2010) 32:379-91. doi:10.1016/j.immuni.2010.03.003
-
(2010)
Immunity
, vol.32
, pp. 379-391
-
-
Zaki, M.H.1
Boyd, K.L.2
Vogel, P.3
Kastan, M.B.4
Lamkanfi, M.5
Kanneganti, T.D.6
-
199
-
-
77949965210
-
Control of intestinal homeostasis, colitis, and colitis-associated colorectal cancer by the inflammatory caspases
-
DoironK, Bergstrom KS, Mcintire CR, Leblanc PM, et al.
-
Dupaul-Chicoine J, Yeretssian G, Doiron K, Bergstrom KS, Mcintire CR, Leblanc PM, et al. Control of intestinal homeostasis, colitis, and colitis-associated colorectal cancer by the inflammatory caspases. Immunity (2010) 32:367-78. doi:10.1016/j.immuni.2010.02.012
-
(2010)
Immunity
, vol.32
, pp. 367-378
-
-
Dupaul-Chicoine, J.1
Yeretssian, G.2
-
200
-
-
78049488908
-
IL-18 production downstream of the Nlrp3 inflammasome confers protection against colorectal tumor formation
-
doi:10.4049/jimmunol.1002046
-
Zaki MH, Vogel P, Body-Malapel M, Lamkanfi M, Kanneganti TD. IL-18 production downstream of the Nlrp3 inflammasome confers protection against colorectal tumor formation. J Immunol (2010) 185:4912-20. doi:10.4049/jimmunol.1002046
-
(2010)
J Immunol
, vol.185
, pp. 4912-4920
-
-
Zaki, M.H.1
Vogel, P.2
Body-Malapel, M.3
Lamkanfi, M.4
Kanneganti, T.D.5
-
201
-
-
77955350419
-
MyD88-mediated signaling prevents development of adenocarcinomas of the colon: role of interleukin 18
-
doi:10.1084/jem.20100199
-
Salcedo R, Worschech A, Cardone M, Jones Y, Gyulai Z, Dai RM, et al. MyD88-mediated signaling prevents development of adenocarcinomas of the colon: role of interleukin 18. J Exp Med (2010) 207:1625-36. doi:10.1084/jem.20100199
-
(2010)
J Exp Med
, vol.207
, pp. 1625-1636
-
-
Salcedo, R.1
Worschech, A.2
Cardone, M.3
Jones, Y.4
Gyulai, Z.5
Dai, R.M.6
-
202
-
-
4644367878
-
Commentary: the role of the IL-18 system and other members of the IL-1R/TLR superfamily in innate mucosal immunity and the pathogenesis of inflammatory bowel disease: friend or foe?
-
doi:10.1002/eji.200425351
-
Reuter BK, Pizarro TT. Commentary: the role of the IL-18 system and other members of the IL-1R/TLR superfamily in innate mucosal immunity and the pathogenesis of inflammatory bowel disease: friend or foe? Eur J Immunol (2004) 34:2347-55. doi:10.1002/eji.200425351
-
(2004)
Eur J Immunol
, vol.34
, pp. 2347-2355
-
-
Reuter, B.K.1
Pizarro, T.T.2
-
203
-
-
77949982382
-
Interleukin-18 in intestinal inflammation: friend and foe?
-
doi:10.1016/j.immuni.2010.03.010
-
Siegmund B. Interleukin-18 in intestinal inflammation: friend and foe? Immunity (2010) 32:300-2. doi:10.1016/j.immuni.2010.03.010
-
(2010)
Immunity
, vol.32
, pp. 300-302
-
-
Siegmund, B.1
-
204
-
-
84886014303
-
Central role of the gut epithelial barrier in the pathogenesis of chronic intestinal inflammation: lessons learned from animal models and human genetics
-
doi:10.3389/fimmu.2013.00280
-
Pastorelli L, De Salvo C, Mercado JR, Vecchi M, Pizarro TT. Central role of the gut epithelial barrier in the pathogenesis of chronic intestinal inflammation: lessons learned from animal models and human genetics. Front Immunol (2013) 4:280. doi:10.3389/fimmu.2013.00280
-
(2013)
Front Immunol
, vol.4
, pp. 280
-
-
Pastorelli, L.1
De Salvo, C.2
Mercado, J.R.3
Vecchi, M.4
Pizarro, T.T.5
-
205
-
-
84891500326
-
Deregulation of the NLRP3 inflammasome in hepatic parenchymal cells during liver cancer progression
-
doi:10.1038/labinvest.2013.126
-
Wei Q, Mu K, Li T, Zhang Y, Yang Z, Jia X, et al. Deregulation of the NLRP3 inflammasome in hepatic parenchymal cells during liver cancer progression. Lab Invest (2014) 94:52-62. doi:10.1038/labinvest.2013.126
-
(2014)
Lab Invest
, vol.94
, pp. 52-62
-
-
Wei, Q.1
Mu, K.2
Li, T.3
Zhang, Y.4
Yang, Z.5
Jia, X.6
-
206
-
-
84868626486
-
Genetic variation and alterations of genes involved in NFkappaB/TNFAIP3- and NLRP3-inflammasome signaling affect susceptibility and outcome of colorectal cancer
-
doi:10.1093/carcin/bgs256
-
Ungerback J, Belenki D, Jawad Ul-Hassan A, Fredrikson M, Fransen K, Elander N, et al. Genetic variation and alterations of genes involved in NFkappaB/TNFAIP3- and NLRP3-inflammasome signaling affect susceptibility and outcome of colorectal cancer. Carcinogenesis (2012) 33:2126-34. doi:10.1093/carcin/bgs256
-
(2012)
Carcinogenesis
, vol.33
, pp. 2126-2134
-
-
Ungerback, J.1
Belenki, D.2
Jawad Ul-Hassan, A.3
Fredrikson, M.4
Fransen, K.5
Elander, N.6
-
207
-
-
84859877626
-
The Q705K polymorphism in NLRP3 is a gain-of-function alteration leading to excessive interleukin-1beta and IL-18 production
-
doi:10.1371/journal.pone.0034977
-
Verma D, Sarndahl E, Andersson H, Eriksson P, Fredrikson M, Jonsson JI, et al. The Q705K polymorphism in NLRP3 is a gain-of-function alteration leading to excessive interleukin-1beta and IL-18 production. PLoS One (2012) 7:e34977. doi:10.1371/journal.pone.0034977
-
(2012)
PLoS One
, vol.7
-
-
Verma, D.1
Sarndahl, E.2
Andersson, H.3
Eriksson, P.4
Fredrikson, M.5
Jonsson, J.I.6
-
208
-
-
84862646126
-
Inflammasome polymorphisms confer susceptibility to sporadic malignant melanoma
-
doi:10.1111/j.1755-148X.2012.01008.x
-
Verma D, Bivik C, Farahani E, Synnerstad I, Fredrikson M, Enerback C, et al. Inflammasome polymorphisms confer susceptibility to sporadic malignant melanoma. Pigment Cell Melanoma Res (2012) 25:506-13. doi:10.1111/j.1755-148X.2012.01008.x
-
(2012)
Pigment Cell Melanoma Res
, vol.25
, pp. 506-513
-
-
Verma, D.1
Bivik, C.2
Farahani, E.3
Synnerstad, I.4
Fredrikson, M.5
Enerback, C.6
-
209
-
-
77949889567
-
Constitutively active inflammasome in human melanoma cells mediating autoinflammation via caspase-1 processing and secretion of interleukin-1beta
-
doi:10.1074/jbc.M109.064907
-
Okamoto M, Liu W, Luo Y, Tanaka A, Cai X, Norris DA, et al. Constitutively active inflammasome in human melanoma cells mediating autoinflammation via caspase-1 processing and secretion of interleukin-1beta. J Biol Chem (2010) 285:6477-88. doi:10.1074/jbc.M109.064907
-
(2010)
J Biol Chem
, vol.285
, pp. 6477-6488
-
-
Okamoto, M.1
Liu, W.2
Luo, Y.3
Tanaka, A.4
Cai, X.5
Norris, D.A.6
-
210
-
-
84869090231
-
Insights into p53 transcriptional function via genome-wide chromatin occupancy and gene expression analysis
-
doi:10.1038/cdd.2012.89
-
Nikulenkov F, Spinnler C, Li H, Tonelli C, Shi Y, Turunen M, et al. Insights into p53 transcriptional function via genome-wide chromatin occupancy and gene expression analysis. Cell Death Differ (2012) 19:1992-2002. doi:10.1038/cdd.2012.89
-
(2012)
Cell Death Differ
, vol.19
, pp. 1992-2002
-
-
Nikulenkov, F.1
Spinnler, C.2
Li, H.3
Tonelli, C.4
Shi, Y.5
Turunen, M.6
-
211
-
-
13244252271
-
Caspase-1 activator Ipaf is a p53-inducible gene involved in apoptosis
-
doi:10.1038/sj.onc.1208201
-
Sadasivam S, Gupta S, Radha V, Batta K, Kundu TK, Swarup G. Caspase-1 activator Ipaf is a p53-inducible gene involved in apoptosis. Oncogene (2005) 24:627-36. doi:10.1038/sj.onc.1208201
-
(2005)
Oncogene
, vol.24
, pp. 627-636
-
-
Sadasivam, S.1
Gupta, S.2
Radha, V.3
Batta, K.4
Kundu, T.K.5
Swarup, G.6
-
212
-
-
79959221313
-
Inflammasome-mediated suppression of inflammation-induced colorectal cancer progression is mediated by direct regulation of epithelial cell proliferation
-
doi:10.4161/cc.10.12.16008
-
Hu B, Elinav E, Flavell RA. Inflammasome-mediated suppression of inflammation-induced colorectal cancer progression is mediated by direct regulation of epithelial cell proliferation. Cell Cycle (2011) 10:1936-9. doi:10.4161/cc.10.12.16008
-
(2011)
Cell Cycle
, vol.10
, pp. 1936-1939
-
-
Hu, B.1
Elinav, E.2
Flavell, R.A.3
-
213
-
-
78650735879
-
Inflammation-induced tumorigenesis in the colon is regulated by caspase-1 and NLRC4
-
doi:10.1073/pnas.1016814108
-
Hu B, Elinav E, Huber S, Booth CJ, Strowig T, Jin C, et al. Inflammation-induced tumorigenesis in the colon is regulated by caspase-1 and NLRC4. Proc Natl Acad Sci U S A (2010) 107:21635-40. doi:10.1073/pnas.1016814108
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 21635-21640
-
-
Hu, B.1
Elinav, E.2
Huber, S.3
Booth, C.J.4
Strowig, T.5
Jin, C.6
-
214
-
-
84859911615
-
NLRC4-driven production of IL-1beta discriminates between pathogenic and commensal bacteria and promotes host intestinal defense
-
doi:10.1038/ni.2263
-
Franchi L, Kamada N, Nakamura Y, Burberry A, Kuffa P, Suzuki S, et al. NLRC4-driven production of IL-1beta discriminates between pathogenic and commensal bacteria and promotes host intestinal defense. Nat Immunol (2012) 13:449-56. doi:10.1038/ni.2263
-
(2012)
Nat Immunol
, vol.13
, pp. 449-456
-
-
Franchi, L.1
Kamada, N.2
Nakamura, Y.3
Burberry, A.4
Kuffa, P.5
Suzuki, S.6
-
215
-
-
18644368579
-
Functional screening of five PYPAF family members identifies PYPAF5 as a novel regulator of NF-kappaB and caspase-1
-
doi:10.1016/S0014-5793(02)03416-6
-
Grenier JM, Wang L, Manji GA, Huang WJ, Al-Garawi A, Kelly R, et al. Functional screening of five PYPAF family members identifies PYPAF5 as a novel regulator of NF-kappaB and caspase-1. FEBS Lett (2002) 530:73-8. doi:10.1016/S0014-5793(02)03416-6
-
(2002)
FEBS Lett
, vol.530
, pp. 73-78
-
-
Grenier, J.M.1
Wang, L.2
Manji, G.A.3
Huang, W.J.4
Al-Garawi, A.5
Kelly, R.6
-
216
-
-
79959540809
-
A functional role for Nlrp6 in intestinal inflammation and tumorigenesis
-
doi:10.4049/jimmunol.1100412
-
Chen GY, Liu M, Wang F, Bertin J, Nunez G. A functional role for Nlrp6 in intestinal inflammation and tumorigenesis. J Immunol (2011) 186:7187-94. doi:10.4049/jimmunol.1100412
-
(2011)
J Immunol
, vol.186
, pp. 7187-7194
-
-
Chen, G.Y.1
Liu, M.2
Wang, F.3
Bertin, J.4
Nunez, G.5
-
217
-
-
79957576718
-
NLRP6 inflammasome regulates colonic microbial ecology and risk for colitis
-
doi:10.1016/j.cell.2011.04.022
-
Elinav E, Strowig T, Kau AL, Henao-Mejia J, Thaiss CA, Booth CJ, et al. NLRP6 inflammasome regulates colonic microbial ecology and risk for colitis. Cell (2011) 145:745-57. doi:10.1016/j.cell.2011.04.022
-
(2011)
Cell
, vol.145
, pp. 745-757
-
-
Elinav, E.1
Strowig, T.2
Kau, A.L.3
Henao-Mejia, J.4
Thaiss, C.A.5
Booth, C.J.6
-
218
-
-
79959369355
-
Nod-like receptor pyrin domain-containing protein 6 (NLRP6) controls epithelial self-renewal and colorectal carcinogenesis upon injury
-
doi:10.1073/pnas.1100981108
-
Normand S, Delanoye-Crespin A, Bressenot A, Huot L, Grandjean T, Peyrin-Biroulet L, et al. Nod-like receptor pyrin domain-containing protein 6 (NLRP6) controls epithelial self-renewal and colorectal carcinogenesis upon injury. Proc Natl Acad Sci U S A (2011) 108:9601-6. doi:10.1073/pnas.1100981108
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, pp. 9601-9606
-
-
Normand, S.1
Delanoye-Crespin, A.2
Bressenot, A.3
Huot, L.4
Grandjean, T.5
Peyrin-Biroulet, L.6
-
219
-
-
84868615556
-
IL-22BP is regulated by the inflammasome and modulates tumorigenesis in the intestine
-
doi:10.1038/nature11535
-
Huber S, Gagliani N, Zenewicz LA, Huber FJ, Bosurgi L, Hu B, et al. IL-22BP is regulated by the inflammasome and modulates tumorigenesis in the intestine. Nature (2012) 491:259-63. doi:10.1038/nature11535
-
(2012)
Nature
, vol.491
, pp. 259-263
-
-
Huber, S.1
Gagliani, N.2
Zenewicz, L.A.3
Huber, F.J.4
Bosurgi, L.5
Hu, B.6
-
220
-
-
0010464874
-
PYPAF7, a novel PYRIN-containing Apaf1-like protein that regulates activation of NF-kappa B and caspase-1-dependent cytokine processing
-
doi:10.1074/jbc.M203915200
-
Wang L, Manji GA, Grenier JM, Al-Garawi A, Merriam S, Lora JM, et al. PYPAF7, a novel PYRIN-containing Apaf1-like protein that regulates activation of NF-kappa B and caspase-1-dependent cytokine processing. J Biol Chem (2002) 277:29874-80. doi:10.1074/jbc.M203915200
-
(2002)
J Biol Chem
, vol.277
, pp. 29874-29880
-
-
Wang, L.1
Manji, G.A.2
Grenier, J.M.3
Al-Garawi, A.4
Merriam, S.5
Lora, J.M.6
-
221
-
-
84864317101
-
The NLRP12 inflammasome recognizes Yersinia pestis
-
doi:10.1016/j.immuni.2012.07.006
-
Vladimer GI, Weng D, Paquette SW, Vanaja SK, Rathinam VA, Aune MH, et al. The NLRP12 inflammasome recognizes Yersinia pestis. Immunity (2012) 37:96-107. doi:10.1016/j.immuni.2012.07.006
-
(2012)
Immunity
, vol.37
, pp. 96-107
-
-
Vladimer, G.I.1
Weng, D.2
Paquette, S.W.3
Vanaja, S.K.4
Rathinam, V.A.5
Aune, M.H.6
-
222
-
-
34447558089
-
Polymorphisms in NACHT-LRR (NLR) genes in atopic dermatitis
-
doi:10.1111/j.1600-0625.2007.00589.x
-
Macaluso F, Nothnagel M, Parwez Q, Petrasch-Parwez E, Bechara FG, Epplen JT, et al. Polymorphisms in NACHT-LRR (NLR) genes in atopic dermatitis. Exp Dermatol (2007) 16:692-8. doi:10.1111/j.1600-0625.2007.00589.x
-
(2007)
Exp Dermatol
, vol.16
, pp. 692-698
-
-
Macaluso, F.1
Nothnagel, M.2
Parwez, Q.3
Petrasch-Parwez, E.4
Bechara, F.G.5
Epplen, J.T.6
-
223
-
-
40349113175
-
Mutations in NALP12 cause hereditary periodic fever syndromes
-
doi:10.1073/pnas.0708616105
-
Jeru I, Duquesnoy P, Fernandes-Alnemri T, Cochet E, Yu JW, Lackmy-Port-Lis M, et al. Mutations in NALP12 cause hereditary periodic fever syndromes. Proc Natl Acad Sci U S A (2008) 105:1614-9. doi:10.1073/pnas.0708616105
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 1614-1619
-
-
Jeru, I.1
Duquesnoy, P.2
Fernandes-Alnemri, T.3
Cochet, E.4
Yu, J.W.5
Lackmy-Port-Lis, M.6
-
224
-
-
78049489590
-
Cutting edge: NLRP12 controls dendritic and myeloid cell migration to affect contact hypersensitivity
-
doi:10.4049/jimmunol.1002227
-
Arthur JC, Lich JD, Ye Z, Allen IC, Gris D, Wilson JE, et al. Cutting edge: NLRP12 controls dendritic and myeloid cell migration to affect contact hypersensitivity. J Immunol (2010) 185:4515-9. doi:10.4049/jimmunol.1002227
-
(2010)
J Immunol
, vol.185
, pp. 4515-4519
-
-
Arthur, J.C.1
Lich, J.D.2
Ye, Z.3
Allen, I.C.4
Gris, D.5
Wilson, J.E.6
-
225
-
-
79953702540
-
Clinical presentation and pathogenesis of cold-induced autoinflammatory disease in a family with recurrence of an NLRP12 mutation
-
doi:10.1002/art.30170
-
Borghini S, Tassi S, Chiesa S, Caroli F, Carta S, Caorsi R, et al. Clinical presentation and pathogenesis of cold-induced autoinflammatory disease in a family with recurrence of an NLRP12 mutation. Arthritis Rheum (2011) 63:830-9. doi:10.1002/art.30170
-
(2011)
Arthritis Rheum
, vol.63
, pp. 830-839
-
-
Borghini, S.1
Tassi, S.2
Chiesa, S.3
Caroli, F.4
Carta, S.5
Caorsi, R.6
-
226
-
-
28844494900
-
The CATERPILLER protein monarch-1 is an antagonist of toll-like receptor-, tumor necrosis factor alpha-, and Mycobacterium tuberculosis-induced pro-inflammatory signals
-
doi:10.1074/jbc.M502820200
-
Williams KL, Lich JD, Duncan JA, Reed W, Rallabhandi P, Moore C, et al. The CATERPILLER protein monarch-1 is an antagonist of toll-like receptor-, tumor necrosis factor alpha-, and Mycobacterium tuberculosis-induced pro-inflammatory signals. J Biol Chem (2005) 280:39914-24. doi:10.1074/jbc.M502820200
-
(2005)
J Biol Chem
, vol.280
, pp. 39914-39924
-
-
Williams, K.L.1
Lich, J.D.2
Duncan, J.A.3
Reed, W.4
Rallabhandi, P.5
Moore, C.6
-
227
-
-
38449087767
-
Heat shock protein 90 associates with monarch-1 and regulates its ability to promote degradation of NF-kappaB-inducing kinase
-
doi:10.4049/jimmunol.179.9.6291
-
Arthur JC, Lich JD, Aziz RK, Kotb M, Ting JP. Heat shock protein 90 associates with monarch-1 and regulates its ability to promote degradation of NF-kappaB-inducing kinase. J Immunol (2007) 179:6291-6. doi:10.4049/jimmunol.179.9.6291
-
(2007)
J Immunol
, vol.179
, pp. 6291-6296
-
-
Arthur, J.C.1
Lich, J.D.2
Aziz, R.K.3
Kotb, M.4
Ting, J.P.5
-
228
-
-
33846473862
-
Monarch-1 suppresses non-canonical NF-kappaB activation and p52-dependent chemokine expression in monocytes
-
doi:10.4049/jimmunol.178.3.1256
-
Lich JD, Williams KL, Moore CB, Arthur JC, Davis BK, Taxman DJ, et al. Monarch-1 suppresses non-canonical NF-kappaB activation and p52-dependent chemokine expression in monocytes. J Immunol (2007) 178:1256-60. doi:10.4049/jimmunol.178.3.1256
-
(2007)
J Immunol
, vol.178
, pp. 1256-1260
-
-
Lich, J.D.1
Williams, K.L.2
Moore, C.B.3
Arthur, J.C.4
Davis, B.K.5
Taxman, D.J.6
-
229
-
-
81255189478
-
The NOD-like receptor NLRP12 attenuates colon inflammation and tumorigenesis
-
doi:10.1016/j.ccr.2011.10.022
-
Zaki MH, Vogel P, Malireddi RK, Body-Malapel M, Anand PK, Bertin J, et al. The NOD-like receptor NLRP12 attenuates colon inflammation and tumorigenesis. Cancer Cell (2011) 20:649-60. doi:10.1016/j.ccr.2011.10.022
-
(2011)
Cancer Cell
, vol.20
, pp. 649-660
-
-
Zaki, M.H.1
Vogel, P.2
Malireddi, R.K.3
Body-Malapel, M.4
Anand, P.K.5
Bertin, J.6
-
230
-
-
84861460062
-
NLRP12 suppresses colon inflammation and tumorigenesis through the negative regulation of noncanonical NF-kappaB signaling
-
doi:10.1016/j.immuni.2012.03.012
-
Allen IC, Wilson JE, Schneider M, Lich JD, Roberts RA, Arthur JC, et al. NLRP12 suppresses colon inflammation and tumorigenesis through the negative regulation of noncanonical NF-kappaB signaling. Immunity (2012) 36:742-54. doi:10.1016/j.immuni.2012.03.012
-
(2012)
Immunity
, vol.36
, pp. 742-754
-
-
Allen, I.C.1
Wilson, J.E.2
Schneider, M.3
Lich, J.D.4
Roberts, R.A.5
Arthur, J.C.6
-
231
-
-
84856988610
-
Simultaneous targeting of toll- and nod-like receptors induces effective tumor-specific immune responses
-
doi:10.1126/scitranslmed.3002868
-
Garaude J, Kent A, Van Rooijen N, Blander JM. Simultaneous targeting of toll- and nod-like receptors induces effective tumor-specific immune responses. Sci Transl Med (2012) 4:120ra116. doi:10.1126/scitranslmed.3002868
-
(2012)
Sci Transl Med
, vol.4
-
-
Garaude, J.1
Kent, A.2
Van Rooijen, N.3
Blander, J.M.4
-
232
-
-
0033959170
-
Intrapleural therapy with MDP-Lys (L18), a synthetic derivative of muramyl dipeptide, against malignant pleurisy associated with lung cancer
-
doi:10.1016/S0169-5002(99)00090-2
-
Yanagawa H, Haku T, Takeuchi E, Suzuki Y, Nokihara H, Sone S. Intrapleural therapy with MDP-Lys (L18), a synthetic derivative of muramyl dipeptide, against malignant pleurisy associated with lung cancer. Lung Cancer (2000) 27:67-73. doi:10.1016/S0169-5002(99)00090-2
-
(2000)
Lung Cancer
, vol.27
, pp. 67-73
-
-
Yanagawa, H.1
Haku, T.2
Takeuchi, E.3
Suzuki, Y.4
Nokihara, H.5
Sone, S.6
-
233
-
-
0034567817
-
Inhibitory effect of liposomal MDP-Lys on lung metastasis of transplantable osteosarcoma in hamster
-
Nitta Y, Sugita T, Ikuta Y, Murakami T. Inhibitory effect of liposomal MDP-Lys on lung metastasis of transplantable osteosarcoma in hamster. Oncol Res (2000) 12:25-31.
-
(2000)
Oncol Res
, vol.12
, pp. 25-31
-
-
Nitta, Y.1
Sugita, T.2
Ikuta, Y.3
Murakami, T.4
-
234
-
-
0028081916
-
MDP-Lys(L18), a lipophilic derivative of muramyl dipeptide, inhibits the metastasis of haematogenous and non-haematogenous tumours in mice
-
doi:10.1016/0264-410X(94)90057-4
-
Yoo YC, Saiki I, Sato K, Azuma I. MDP-Lys(L18), a lipophilic derivative of muramyl dipeptide, inhibits the metastasis of haematogenous and non-haematogenous tumours in mice. Vaccine (1994) 12:175-260. doi:10.1016/0264-410X(94)90057-4
-
(1994)
Vaccine
, vol.12
, pp. 175-260
-
-
Yoo, Y.C.1
Saiki, I.2
Sato, K.3
Azuma, I.4
-
235
-
-
79954612111
-
A synthetic NOD2 agonist, muramyl dipeptide (MDP)-Lys (L18) and IFN-beta synergistically induce dendritic cell maturation with augmented IL-12 production and suppress melanoma growth
-
doi:10.1016/j.jdermsci.2011.02.002
-
Fujimura T, Yamasaki K, Hidaka T, Ito Y, Aiba S. A synthetic NOD2 agonist, muramyl dipeptide (MDP)-Lys (L18) and IFN-beta synergistically induce dendritic cell maturation with augmented IL-12 production and suppress melanoma growth. J Dermatol Sci (2011) 62:107-15. doi:10.1016/j.jdermsci.2011.02.002
-
(2011)
J Dermatol Sci
, vol.62
, pp. 107-115
-
-
Fujimura, T.1
Yamasaki, K.2
Hidaka, T.3
Ito, Y.4
Aiba, S.5
-
236
-
-
84869206979
-
NLRP3 suppresses NK cell-mediated responses to carcinogen-induced tumors and metastases
-
doi:10.1158/0008-5472.CAN-12-0509
-
Chow MT, Sceneay J, Paget C, Wong CS, Duret H, Tschopp J, et al. NLRP3 suppresses NK cell-mediated responses to carcinogen-induced tumors and metastases. Cancer Res (2012) 72:5721-32. doi:10.1158/0008-5472.CAN-12-0509
-
(2012)
Cancer Res
, vol.72
, pp. 5721-5732
-
-
Chow, M.T.1
Sceneay, J.2
Paget, C.3
Wong, C.S.4
Duret, H.5
Tschopp, J.6
-
237
-
-
84872086179
-
Chemotherapy-triggered cathepsin B release in myeloid-derived suppressor cells activates the Nlrp3 inflammasome and promotes tumor growth
-
doi:10.1038/nm.2999
-
Bruchard M, Mignot G, Derangere V, Chalmin F, Chevriaux A, Vegran F, et al. Chemotherapy-triggered cathepsin B release in myeloid-derived suppressor cells activates the Nlrp3 inflammasome and promotes tumor growth. Nat Med (2013) 19:57-64. doi:10.1038/nm.2999
-
(2013)
Nat Med
, vol.19
, pp. 57-64
-
-
Bruchard, M.1
Mignot, G.2
Derangere, V.3
Chalmin, F.4
Chevriaux, A.5
Vegran, F.6
-
238
-
-
84858643750
-
Inflammasomes in carcinogenesis and anticancer immune responses
-
doi:10.1038/ni.2224
-
Zitvogel L, Kepp O, Galluzzi L, Kroemer G. Inflammasomes in carcinogenesis and anticancer immune responses. Nat Immunol (2012) 13:343-51. doi:10.1038/ni.2224
-
(2012)
Nat Immunol
, vol.13
, pp. 343-351
-
-
Zitvogel, L.1
Kepp, O.2
Galluzzi, L.3
Kroemer, G.4
-
239
-
-
61449122079
-
Induction of a chronic disease state in patients with smoldering or indolent multiple myeloma by targeting interleukin 1{beta}-induced interleukin 6 production and the myeloma proliferative component
-
doi:10.4065/84.2.114
-
Lust JA, Lacy MQ, Zeldenrust SR, Dispenzieri A, Gertz MA, Witzig TE, et al. Induction of a chronic disease state in patients with smoldering or indolent multiple myeloma by targeting interleukin 1{beta}-induced interleukin 6 production and the myeloma proliferative component. Mayo Clin Proc (2009) 84:114-22. doi:10.4065/84.2.114
-
(2009)
Mayo Clin Proc
, vol.84
, pp. 114-122
-
-
Lust, J.A.1
Lacy, M.Q.2
Zeldenrust, S.R.3
Dispenzieri, A.4
Gertz, M.A.5
Witzig, T.E.6
-
240
-
-
80051698136
-
IL-18 induces PD-1-dependent immunosuppression in cancer
-
doi:10.1158/0008-5472.CAN-11-0993
-
Terme M, Ullrich E, Aymeric L, Meinhardt K, Desbois M, Delahaye N, et al. IL-18 induces PD-1-dependent immunosuppression in cancer. Cancer Res (2011) 71:5393-9. doi:10.1158/0008-5472.CAN-11-0993
-
(2011)
Cancer Res
, vol.71
, pp. 5393-5399
-
-
Terme, M.1
Ullrich, E.2
Aymeric, L.3
Meinhardt, K.4
Desbois, M.5
Delahaye, N.6
-
241
-
-
84861888837
-
Cancer-induced immunosuppression: IL-18-elicited immunoablative NK cells
-
doi:10.1158/0008-5472.CAN-11-3379
-
Terme M, Ullrich E, Aymeric L, Meinhardt K, Coudert JD, Desbois M, et al. Cancer-induced immunosuppression: IL-18-elicited immunoablative NK cells. Cancer Res (2012) 72:2757-67. doi:10.1158/0008-5472.CAN-11-3379
-
(2012)
Cancer Res
, vol.72
, pp. 2757-2767
-
-
Terme, M.1
Ullrich, E.2
Aymeric, L.3
Meinhardt, K.4
Coudert, J.D.5
Desbois, M.6
|