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Volumn 36, Issue 5, 2012, Pages 742-754

NLRP12 Suppresses Colon Inflammation and Tumorigenesis through the Negative Regulation of Noncanonical NF-κB Signaling

Author keywords

[No Author keywords available]

Indexed keywords

CXCL13 CHEMOKINE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; NLRP12 PROTEIN; PROTEIN KINASE B; PROTEIN P100; PROTEIN P52; STROMAL CELL DERIVED FACTOR 1; TRANSCRIPTION FACTOR; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 3; UNCLASSIFIED DRUG;

EID: 84861460062     PISSN: 10747613     EISSN: 10974180     Source Type: Journal    
DOI: 10.1016/j.immuni.2012.03.012     Document Type: Article
Times cited : (412)

References (41)
  • 1
    • 77949755113 scopus 로고    scopus 로고
    • IKKalpha and IKKbeta each function to regulate NF-kappaB activation in the TNF-induced/canonical pathway
    • Adli M., Merkhofer E., Cogswell P., Baldwin A.S. IKKalpha and IKKbeta each function to regulate NF-kappaB activation in the TNF-induced/canonical pathway. PLoS ONE 2010, 5:e9428.
    • (2010) PLoS ONE , vol.5
    • Adli, M.1    Merkhofer, E.2    Cogswell, P.3    Baldwin, A.S.4
  • 7
    • 57749094105 scopus 로고    scopus 로고
    • The innate immune receptor Nod1 protects the intestine from inflammation-induced tumorigenesis
    • Chen G.Y., Shaw M.H., Redondo G., Núñez G. The innate immune receptor Nod1 protects the intestine from inflammation-induced tumorigenesis. Cancer Res. 2008, 68:10060-10067.
    • (2008) Cancer Res. , vol.68 , pp. 10060-10067
    • Chen, G.Y.1    Shaw, M.H.2    Redondo, G.3    Núñez, G.4
  • 9
    • 0037040901 scopus 로고    scopus 로고
    • A novel NF-kappa B-inducing kinase-MAPK signaling pathway up-regulates NF-kappa B activity in melanoma cells
    • Dhawan P., Richmond A. A novel NF-kappa B-inducing kinase-MAPK signaling pathway up-regulates NF-kappa B activity in melanoma cells. J. Biol. Chem. 2002, 277:7920-7928.
    • (2002) J. Biol. Chem. , vol.277 , pp. 7920-7928
    • Dhawan, P.1    Richmond, A.2
  • 11
    • 33645746888 scopus 로고    scopus 로고
    • Adenoviral gene transfer of stromal cell-derived factor-1 to murine tumors induces the accumulation of dendritic cells and suppresses tumor growth
    • Fushimi T., O'Connor T.P., Crystal R.G. Adenoviral gene transfer of stromal cell-derived factor-1 to murine tumors induces the accumulation of dendritic cells and suppresses tumor growth. Cancer Res. 2006, 66:3513-3522.
    • (2006) Cancer Res. , vol.66 , pp. 3513-3522
    • Fushimi, T.1    O'Connor, T.P.2    Crystal, R.G.3
  • 14
    • 38849098412 scopus 로고    scopus 로고
    • NF-kappaB and the intestine: friend or foe?
    • Karrasch T., Jobin C. NF-kappaB and the intestine: friend or foe?. Inflamm. Bowel Dis. 2008, 14:114-124.
    • (2008) Inflamm. Bowel Dis. , vol.14 , pp. 114-124
    • Karrasch, T.1    Jobin, C.2
  • 18
    • 33846473862 scopus 로고    scopus 로고
    • Monarch-1 suppresses non-canonical NF-kappaB activation and p52-dependent chemokine expression in monocytes
    • Lich J.D., Williams K.L., Moore C.B., Arthur J.C., Davis B.K., Taxman D.J., Ting J.P. Monarch-1 suppresses non-canonical NF-kappaB activation and p52-dependent chemokine expression in monocytes. J. Immunol. 2007, 178:1256-1260.
    • (2007) J. Immunol. , vol.178 , pp. 1256-1260
    • Lich, J.D.1    Williams, K.L.2    Moore, C.B.3    Arthur, J.C.4    Davis, B.K.5    Taxman, D.J.6    Ting, J.P.7
  • 19
    • 78649670803 scopus 로고    scopus 로고
    • Classical NF-kappaB activation negatively regulates noncanonical NF-kappaB-dependent CXCL12 expression
    • Madge L.A., May M.J. Classical NF-kappaB activation negatively regulates noncanonical NF-kappaB-dependent CXCL12 expression. J. Biol. Chem. 2010, 285:38069-38077.
    • (2010) J. Biol. Chem. , vol.285 , pp. 38069-38077
    • Madge, L.A.1    May, M.J.2
  • 21
    • 47949090079 scopus 로고    scopus 로고
    • The role of myeloid cells in the promotion of tumour angiogenesis
    • Murdoch C., Muthana M., Coffelt S.B., Lewis C.E. The role of myeloid cells in the promotion of tumour angiogenesis. Nat. Rev. Cancer 2008, 8:618-631.
    • (2008) Nat. Rev. Cancer , vol.8 , pp. 618-631
    • Murdoch, C.1    Muthana, M.2    Coffelt, S.B.3    Lewis, C.E.4
  • 22
    • 34548162712 scopus 로고    scopus 로고
    • An inducible mouse model of colon carcinogenesis for the analysis of sporadic and inflammation-driven tumor progression
    • Neufert C., Becker C., Neurath M.F. An inducible mouse model of colon carcinogenesis for the analysis of sporadic and inflammation-driven tumor progression. Nat. Protoc. 2007, 2:1998-2004.
    • (2007) Nat. Protoc. , vol.2 , pp. 1998-2004
    • Neufert, C.1    Becker, C.2    Neurath, M.F.3
  • 23
    • 18844428327 scopus 로고    scopus 로고
    • Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion
    • Orimo A., Gupta P.B., Sgroi D.C., Arenzana-Seisdedos F., Delaunay T., Naeem R., Carey V.J., Richardson A.L., Weinberg R.A. Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion. Cell 2005, 121:335-348.
    • (2005) Cell , vol.121 , pp. 335-348
    • Orimo, A.1    Gupta, P.B.2    Sgroi, D.C.3    Arenzana-Seisdedos, F.4    Delaunay, T.5    Naeem, R.6    Carey, V.J.7    Richardson, A.L.8    Weinberg, R.A.9
  • 24
    • 34250888664 scopus 로고    scopus 로고
    • Nod1/RICK and TLR signaling regulate chemokine and antimicrobial innate immune responses in mesothelial cells
    • Park J.H., Kim Y.G., Shaw M., Kanneganti T.D., Fujimoto Y., Fukase K., Inohara N., Núñez G. Nod1/RICK and TLR signaling regulate chemokine and antimicrobial innate immune responses in mesothelial cells. J. Immunol. 2007, 179:514-521.
    • (2007) J. Immunol. , vol.179 , pp. 514-521
    • Park, J.H.1    Kim, Y.G.2    Shaw, M.3    Kanneganti, T.D.4    Fujimoto, Y.5    Fukase, K.6    Inohara, N.7    Núñez, G.8
  • 25
    • 3242664636 scopus 로고    scopus 로고
    • Recognition of commensal microflora by toll-like receptors is required for intestinal homeostasis
    • Rakoff-Nahoum S., Paglino J., Eslami-Varzaneh F., Edberg S., Medzhitov R. Recognition of commensal microflora by toll-like receptors is required for intestinal homeostasis. Cell 2004, 118:229-241.
    • (2004) Cell , vol.118 , pp. 229-241
    • Rakoff-Nahoum, S.1    Paglino, J.2    Eslami-Varzaneh, F.3    Edberg, S.4    Medzhitov, R.5
  • 26
    • 77953824286 scopus 로고    scopus 로고
    • Negative feedback in noncanonical NF-kappaB signaling modulates NIK stability through IKKalpha-mediated phosphorylation
    • Razani B., Zarnegar B., Ytterberg A.J., Shiba T., Dempsey P.W., Ware C.F., Loo J.A., Cheng G. Negative feedback in noncanonical NF-kappaB signaling modulates NIK stability through IKKalpha-mediated phosphorylation. Sci. Signal. 2010, 3:ra41.
    • (2010) Sci. Signal. , vol.3
    • Razani, B.1    Zarnegar, B.2    Ytterberg, A.J.3    Shiba, T.4    Dempsey, P.W.5    Ware, C.F.6    Loo, J.A.7    Cheng, G.8
  • 29
    • 53149124431 scopus 로고    scopus 로고
    • Animal models of inflammatory bowel disease at the dawn of the new genetics era
    • Sollid L.M., Johansen F.E. Animal models of inflammatory bowel disease at the dawn of the new genetics era. PLoS Med. 2008, 5:e198.
    • (2008) PLoS Med. , vol.5
    • Sollid, L.M.1    Johansen, F.E.2
  • 30
    • 78650920066 scopus 로고    scopus 로고
    • Non-canonical NF-κB signaling pathway
    • Sun S.C. Non-canonical NF-κB signaling pathway. Cell Res. 2011, 21:71-85.
    • (2011) Cell Res. , vol.21 , pp. 71-85
    • Sun, S.C.1
  • 31
    • 77956407149 scopus 로고    scopus 로고
    • NF-κB inducing kinase: a key regulator in the immune system and in cancer
    • Thu Y.M., Richmond A. NF-κB inducing kinase: a key regulator in the immune system and in cancer. Cytokine Growth Factor Rev. 2010, 21:213-226.
    • (2010) Cytokine Growth Factor Rev. , vol.21 , pp. 213-226
    • Thu, Y.M.1    Richmond, A.2
  • 32
    • 74549206702 scopus 로고    scopus 로고
    • How the noninflammasome NLRs function in the innate immune system
    • Ting J.P., Duncan J.A., Lei Y. How the noninflammasome NLRs function in the innate immune system. Science 2010, 327:286-290.
    • (2010) Science , vol.327 , pp. 286-290
    • Ting, J.P.1    Duncan, J.A.2    Lei, Y.3
  • 33
    • 37549000073 scopus 로고    scopus 로고
    • Flat colorectal cancers are genetically determined and progress to invasion without going through a polypoid stage
    • Uronis J.M., Herfarth H.H., Rubinas T.C., Bissahoyo A.C., Hanlon K., Threadgill D.W. Flat colorectal cancers are genetically determined and progress to invasion without going through a polypoid stage. Cancer Res. 2007, 67:11594-11600.
    • (2007) Cancer Res. , vol.67 , pp. 11594-11600
    • Uronis, J.M.1    Herfarth, H.H.2    Rubinas, T.C.3    Bissahoyo, A.C.4    Hanlon, K.5    Threadgill, D.W.6
  • 34
    • 56349164232 scopus 로고    scopus 로고
    • Nonredundant and complementary functions of TRAF2 and TRAF3 in a ubiquitination cascade that activates NIK-dependent alternative NF-kappaB signaling
    • Vallabhapurapu S., Matsuzawa A., Zhang W., Tseng P.H., Keats J.J., Wang H., Vignali D.A., Bergsagel P.L., Karin M. Nonredundant and complementary functions of TRAF2 and TRAF3 in a ubiquitination cascade that activates NIK-dependent alternative NF-kappaB signaling. Nat. Immunol. 2008, 9:1364-1370.
    • (2008) Nat. Immunol. , vol.9 , pp. 1364-1370
    • Vallabhapurapu, S.1    Matsuzawa, A.2    Zhang, W.3    Tseng, P.H.4    Keats, J.J.5    Wang, H.6    Vignali, D.A.7    Bergsagel, P.L.8    Karin, M.9
  • 36
    • 85046913982 scopus 로고    scopus 로고
    • Constitutive non-canonical NFkappaB signaling in pancreatic cancer cells
    • Wharry C.E., Haines K.M., Carroll R.G., May M.J. Constitutive non-canonical NFkappaB signaling in pancreatic cancer cells. Cancer Biol. Ther. 2009, 8:1567-1576.
    • (2009) Cancer Biol. Ther. , vol.8 , pp. 1567-1576
    • Wharry, C.E.1    Haines, K.M.2    Carroll, R.G.3    May, M.J.4
  • 37
    • 28844494900 scopus 로고    scopus 로고
    • The CATERPILLER protein monarch-1 is an antagonist of toll-like receptor-, tumor necrosis factor alpha-, and Mycobacterium tuberculosis-induced pro-inflammatory signals
    • Williams K.L., Lich J.D., Duncan J.A., Reed W., Rallabhandi P., Moore C., Kurtz S., Coffield V.M., Accavitti-Loper M.A., Su L., et al. The CATERPILLER protein monarch-1 is an antagonist of toll-like receptor-, tumor necrosis factor alpha-, and Mycobacterium tuberculosis-induced pro-inflammatory signals. J. Biol. Chem. 2005, 280:39914-39924.
    • (2005) J. Biol. Chem. , vol.280 , pp. 39914-39924
    • Williams, K.L.1    Lich, J.D.2    Duncan, J.A.3    Reed, W.4    Rallabhandi, P.5    Moore, C.6    Kurtz, S.7    Coffield, V.M.8    Accavitti-Loper, M.A.9    Su, L.10
  • 39
    • 78049488908 scopus 로고    scopus 로고
    • IL-18 production downstream of the Nlrp3 inflammasome confers protection against colorectal tumor formation
    • Zaki M.H., Vogel P., Body-Malapel M., Lamkanfi M., Kanneganti T.D. IL-18 production downstream of the Nlrp3 inflammasome confers protection against colorectal tumor formation. J. Immunol. 2010, 185:4912-4920.
    • (2010) J. Immunol. , vol.185 , pp. 4912-4920
    • Zaki, M.H.1    Vogel, P.2    Body-Malapel, M.3    Lamkanfi, M.4    Kanneganti, T.D.5
  • 41
    • 42149110830 scopus 로고    scopus 로고
    • Control of canonical NF-kappaB activation through the NIK-IKK complex pathway
    • Zarnegar B., Yamazaki S., He J.Q., Cheng G. Control of canonical NF-kappaB activation through the NIK-IKK complex pathway. Proc. Natl. Acad. Sci. USA 2008, 105:3503-3508.
    • (2008) Proc. Natl. Acad. Sci. USA , vol.105 , pp. 3503-3508
    • Zarnegar, B.1    Yamazaki, S.2    He, J.Q.3    Cheng, G.4


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