NLRX1 Protein Attenuates Inflammatory Responses to Infection by Interfering with the RIG-I-MAVS and TRAF6-NF-κB Signaling Pathways

Immunity

Volumn 34, Issue 6, 2011, Pages 854-865

  Allen, Irving C ^a   Moore, Chris B ^c   Schneider, Monika ^b   Lei, Yu ^a   Davis, Beckley K ^a   Scull, Margaret A ^b   Gris, Denis ^a   Roney, Kelly E ^b   Zimmermann, Albert G ^a   Bowzard, John B ^d   Ranjan, Priya ^d   Monroe, Kathryn M ^e   Pickles, Raymond J ^b   Sambhara, Suryaprakash ^d   Ting, Jenny P Y ^a,b  

^a UNIVERSITY OF NORTH CAROLINA   (United States)

^b UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^c Metabolic and Viral Diseases Center of Excellence for Drug Discovery   (United States)

^d NATIONAL CENTER FOR IMMUNIZATION AND RESPIRATORY DISEASES   (United States)

^e UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA INTERFERON; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 6; MITOCHONDRIAL PROTEIN; NUCLEOTIDE BINDING OLIGOMERIZATION DOMAIN PROTEIN; PROTEIN NLRX1; RETINOIC ACID INDUCIBLE PROTEIN I; STAT2 PROTEIN; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 6; UNCLASSIFIED DRUG;

2009 H1N1 INFLUENZA; ANIMAL CELL; ARTICLE; ATTENUATION; CONTROLLED STUDY; FEMALE; GENE DELETION; HISTOPATHOLOGY; INFLAMMATION; INNATE IMMUNITY; MACROPHAGE ACTIVATION; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; CELLS, CULTURED; INFLUENZA A VIRUS, H1N1 SUBTYPE; INTERFERON-BETA; INTERLEUKIN-6; MACROPHAGES; MEMBRANE PROTEINS; MICE; MICE, KNOCKOUT; MITOCHONDRIAL PROTEINS; NERVE TISSUE PROTEINS; NF-KAPPA B; ORTHOMYXOVIRIDAE INFECTIONS; SIGNAL TRANSDUCTION; TNF RECEPTOR-ASSOCIATED FACTOR 6;

EID: 79959350721     PISSN: 10747613     EISSN: 10974180     Source Type: Journal    
DOI: 10.1016/j.immuni.2011.03.026     Document Type: Article

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