MyD88-mediated signaling prevents development of adenocarcinomas of the colon: Role of interleukin 18

Journal of Experimental Medicine

Volumn 207, Issue 8, 2010, Pages 1625-1636

  Salcedo, Rosalba ^a,c   Worschech, Andrea ^d   Cardone, Marco ^a   Jones, Yava ^a   Gyulai, Zsofia ^a   Dai, Ren Ming ^a,c   Wang, Ena ^d   Ma, Winnie ^a   Haines, Diana ^b   O'hUigin, Colm ^a,c   Marincola, Francesco M ^d   Trinchieri, Giorgio ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b Pathology/Histotechnology Laboratory   (United States)

^c SAIC FREDERICK INC   (United States)

^d NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AZOXYMETHANE; BETA CATENIN; DEXTRAN SULFATE; INTERLEUKIN 18; INTERLEUKIN 18 RECEPTOR; MYELOID DIFFERENTIATION FACTOR 88; STAT3 PROTEIN; TOLL LIKE RECEPTOR 2; CYCLOOXYGENASE 2; IL18R1 PROTEIN, MOUSE; INTERLEUKIN 1 RECEPTOR TYPE I; INTERLEUKIN 18 RECEPTOR ALPHA; MYD88 PROTEIN, MOUSE; POLYDEOXYRIBONUCLEOTIDE SYNTHASE; PTGS2 PROTEIN, MOUSE; STAT3 PROTEIN, MOUSE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CANCER SUSCEPTIBILITY; CELL PROLIFERATION; COLITIS; COLON ADENOCARCINOMA; COLON CARCINOGENESIS; COLON POLYP; COLON ULCER; CONTROLLED STUDY; DISEASE PREDISPOSITION; DNA DAMAGE; DNA REPAIR; GENE EXPRESSION; GENE MUTATION; INTESTINE EPITHELIUM CELL; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPE; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; WILD TYPE; ADENOCARCINOMA; ANIMAL; C57BL MOUSE; CHEMICALLY INDUCED; COLON; COLON TUMOR; DRUG EFFECTS; EPITHELIUM CELL; GENE EXPRESSION PROFILING; GENETIC PREDISPOSITION; GENETICS; GERMFREE ANIMAL; INFLAMMATORY BOWEL DISEASE; INTESTINE MUCOSA; KNOCKOUT MOUSE; METABOLISM; MUTATION; PATHOLOGY; PHOSPHORYLATION; PHYSIOLOGY;

ADENOCARCINOMA; ANIMALS; APOPTOSIS; AZOXYMETHANE; BETA CATENIN; CELL PROLIFERATION; COLON; COLONIC NEOPLASMS; COLONIC POLYPS; CYCLOOXYGENASE 2; DEXTRAN SULFATE; DNA REPAIR ENZYMES; EPITHELIAL CELLS; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENETIC PREDISPOSITION TO DISEASE; INFLAMMATORY BOWEL DISEASES; INTERLEUKIN-18; INTERLEUKIN-18 RECEPTOR ALPHA SUBUNIT; INTESTINAL MUCOSA; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MUTATION; MYELOID DIFFERENTIATION FACTOR 88; PHOSPHORYLATION; RECEPTORS, INTERLEUKIN-1 TYPE I; SIGNAL TRANSDUCTION; SPECIFIC PATHOGEN-FREE ORGANISMS; STAT3 TRANSCRIPTION FACTOR;

EID: 77955350419     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.20100199     Document Type: Article

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