Lipopolysaccharide activates caspase-1 (interleukin-1-converting enzyme) in cultured monocytic and endothelial cells

Blood

Volumn 91, Issue 2, 1998, Pages 577-584

  Schumann, Ralf R ^a   Belka, Claus ^b   Reuter, Dirk ^b   Lamping, Norbert ^b   Kirschning, Carsten J ^b   Weber, Joerg R ^b   Pfeil, Dagmar ^b  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; LIPOPOLYSACCHARIDE;

ARTICLE; CONTROLLED STUDY; ENDOTHELIUM CELL; ENZYME ACTIVATION; HUMAN; HUMAN CELL; IMMUNOMODULATION; MONOCYTE; PRIORITY JOURNAL; PROTEIN INDUCTION; VASCULAR ENDOTHELIUM;

EID: 0031973493     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v91.2.577     Document Type: Article

References (54)

1. Dinarello CA: Biologic basis for interleukin-1 in disease. Blood 87:2095, 1996
2. Oppenheim JJ, Kovacs EJ, Matsushima K, Durum SK: There is more than one interleukin-1. Immunol Today 7:45, 1986
3. Dinarello CA, Thompson RC: Blocking IL-1: IL-1RA in vivo and in vitro. Immunol Today 12:404, 1991
4. Dinarello CA, Wolff SM: The role of interleukin-1 disease. N Engl J Med 328:106, 1993
5. Dower SK, Kronheim SR, Hopp TP, Cantrell M, Deeley M, Gillis S, Henney CS: The cell surface receptors for interleukin-1 alpha and interleukin-1 beta. Nature 324:266, 1986
6. Grassi J, Roberge CJ, Frobert Y, Pradelles P, Poubelle PE: Determination of L1α, IL1β, and IL2 in biological media using specific enzyme immunometric assays. Immunol Rev 119:125, 1991
7. Hazuda DJ, Lee JC, Young PR: The kinetics of interleukin 1 secretion from activated monocytes. J Biol Chem 263:8473, 1988
8. Lonnemann G, Endres S, Van dMJ, Cannon JG, Koch KM, Dinarello CA: Differences in the synthesis and kinetics of release of interleukin 1. Eur J Immunol 19:1531, 1989
9. Kostura MJ, Tocci MJ, Limjuco G, Chin J, Cameron P. Hillman AG: Identification of a monocyte specific pre-interleukin 1 beta convertase. Proc Natl Acad Sci USA 86:5227, 1989
10. Black RA, Kronheim SR, Sleath PR: Activation of interleukin-1 beta by a co-induced protease. FEBS Lett 247:386, 1989
11. Cerretti DP, Kozlosky CJ, Mosley B, Nelson N, Van NK, Greenstreet TA: Molecular cloning of the interleukin-1 beta converting enzyme. Science 256:97, 1992
12. Alnemri ES, Livingston DJ, Nicholson DW, Salvesen G, Thornberry NA, Wong WW, Yuan J: Human ICE/CED-3 protease nomenclature [letter]. Cell 87:171, 1996
13. Smith DJ, McGuire MJ, Tocci MJ, Thiele DL: IL-1 beta convertase (ICE) does not play a requisite role in apoptosis induced in T lymphoblasts by Fas-dependent or Fas-independent CTL effector mechanisms. J Immunol 158:163, 1997
14. Tatsuta T, Cheng J, Mountz JD: Intracellular IL-1 beta is an inhibitor of Fas-mediated apoptosis. J Immunol 157:3949, 1996
15. Enari M, Talanian RV, Wong WW, Nagata S: Sequential activation of ICE-like and CPP32-like proteases during Fas-mediated apoptosis. Nature 380:723, 1996
16. Thornberry NA, Bull HG, Calaycay JR, Chapman KT, Howard AD, Kostura MJ, Miller DK, Molineaux SM, Weidner JR, Aunins J, Elliston KO, Ayala JM, Casano FJ, Chin J, Ding GJ-F, Egger LA, Gaffney EP, Limjuco G, Palyha OC, Raju SM, Rolando AM, Salley JP, Yamin T-T, Lee TD, Shively JE, MacCross M, Mumford RA, Schmidt JA, Tocci MJ: A novel heterodimeric cysteine protease is required for interleukin-1 beta processing in monocytes. Nature 356:768, 1992
17. Higgins GC, Foster JL, Postlethwaite AE: Interleukin 1 beta propeptide is detected intracellularly and extracellularly when human monocytes are stimulated with LPS in vitro. J Exp Med 180:607, 1994
18. Thornberry NA, Molineaux SM: Interleukin-1β converting enzyme: A novel cysteine protease required. Prot Sci 4:3, 1995
19. Howard AD, Kostura MJ, Thronberry N, Ding GJ, Limjuco G, Weidner J, Salley JP, Hogquist KA, Chaplin DD, Mumford RA, et al: IL-1-converting enzyme requires aspartic acid residues for processing of the IL-1 beta precursor at two distinct sites and does not cleave 31-kDa IL-1 alpha. J Immunol 147:2964, 1991
20. Gu Y, Kuida K, Tsutsui H, Ku G, Hsiao K, Fleming MA, Hayashi N, Higashino K, Okamura H, Nakanishi K, Kurimoto M, Tanimoto T, Flavell RA, Sato V, Harding MW, Livingston DJ, Su MS: Activation of interferon-gamma inducing factor mediated by interleukin-1 beta converting enzyme. Science 275:206, 1997
21. Schonbeck U, Herzberg M, Petersen A, Wohlenberg C, Gerdes J, Flad HD, Loppnow H: Human vascular smooth muscle cells express interleukin-1 beta-converting enzyme (ICE), but inhibit processing of the interleukin-1 beta precursor by ICE. J Exp Med 185:1287, 1997
22. Chapman KT: Synthesis of a potent, reversible inhibitor of interleukin-1β converting enzyme. Bioorg Med Chem Lett 2:613, 1992
23. Fletcher DS, Agarwal L., Chapman KT, Chin J, Egger LA, Limjuco G, Luell S, Macintyre DE, Peterson EP. Thornberry NA, Kostura MJ: A synthetic inhibitor of interleukin-1-beta converting enzyme prevents endotoxin-induced interleukin-1-beta production in vitro and in vivo. J Interferon Cytokin Res 15:243, 1995
24. Thornberry NA: Interleukin-1β converting enzyme. Methods Enzymol 244:615, 1994
25. Ayala JM, Yamin TT, Egger LA, Chin J, Kostura MJ, Miller DK: IL-1 beta-converting enzyme is present in monocytic cells as an inactive 45-kDa precursor. J Immunol 153:2592, 1994
26. Miller DK, Ayala JM, Eggert LA, Raju SM, Yamin T-T, Ding GJ-F, Gaffney EP, Howard AD, Palyha OC, Rolando AM, Salley JP, Thornberry NA, Weidner JR, Williams JH, Chapman KT, Jackson J, Kostura MJ, Limjuco G, Molineaux SM, Mumford RA, Calaycay JR: Purification and characterization of active human interleukin-1b-converting enzyme from THP.1 monocytic cells. J Biol Chem 268: 18062, 1993
27. Yamin T-T, Ayala JM, Miller DK: Activation of the native 45-kDa precursor form of interleukin-1-converting enzyme. J Biol Chem 271:13273, 1996
28. Rietschel ET, Brade H, Holst O, Brade L, Müller-Loennies S, Mamat U, Zähringer U, Beckmann F, Seydel U, Brandenburg K, Ulmer AJ, Mattem T, Heine H, Schletter J, Hauschildt D, Loppnow H, Flad H-D, Schade UF, DiPadova F, Schumann RR: Pathology of septic shock: Bacterial endotoxin: Chemical constitution, biological recognition, host response and immunological detoxification. Curr Top Microbiol Immunol 216:40, 1996
29. Schumann R, Leong SR, Flaggs GW, Gray PW, Wright SD, Mathison JC, Tobias PS, Ulevitch RJ: Structure and function of lipopolysaccharide binding protein. Science 249:1429, 1990
30. Wright SD, Ramos RA, Tobias PS, Ulevitch RJ, Mathison JC: CD14, a receptor for complexes of lipopolysaccharide (LPS) and LPS binding protein. Science 249:1431, 1990
31. Frey EA, Miller DS, Jahr TG, Sundan A, Brazil V, Espevik T, Finlay BB, Wright SD: Soluble CD14 participates in the response of cells to lipopolysaccharide. J Exp Med 176:1665, 1992
32. Pugin J, Schürer-Maly C-C, Leturcq D, Moriarty A, Ulevitch RJ, Tobias PS: Lipopolysaccharide activation of human endothelial and epithelial cells is mediated by lipopolysaccharide-binding protein and soluble CD14. Proc Natl Acad Sci USA 90:2744, 1993
33. Jaffe EA, Nachman RL, Becker CG, Minick CR: Culture of human endothelial cells derived from umbilical veins. Identification by morphologic and immunologic criteria. J Clin Invest 52:2745, 1973
34. +. Blood 87:2805, 1996
35. Fleit HB, Kobasiuk CD: The human monocyte-like cell line THP-1 expresses Fc gamma RI and Fc gamma RII. J Leukoc Biol 49:556, 1991
36. Bradford MM: A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72:248, 1976
37. Sambrock J, Fritsch EF, Maniatis T: Extraction, purification, and analysis of messenger RNA from eukaryotic cells, in Molecular Cloning, vol. 1. Cold Spring Harbor, NY, Cold Spring Harbor Laboratory, 1989, p 7.10
38. Miller DK, Calaycay JR, Chapman KT, Howard AD, Kostura MJ, Molineaux SM: The IL-1 beta converting enzyme as a therapeutic target. Ann NY Acad Sci 696:133, 1993
39. Herzyk DJ, Allen JN, Marsh CB, Wewers MD: Macrophage and monocyte IL-1 beta regulation differs at multiple sites. Messenger RNA expression, translation, and post-translational processing. J Immunol 149:3052, 1992
40. Wewers MD, Herzyk DJ: Alveolar macrophages differ from blood monocytes in human IL-1 beta release. Quantitation by enzyme-linked immunoassay. J Immunol 143:1635, 1989
41. Ariizumi K, Kitajima T, Bergstresser PR, Takashima A: Interleukin-1-beta converting enzyme in murine langerhans cells and epidermal-derived dendritic cell lines. Eur J Immunol 25:2137, 1995
42. Gu Y, Wu J, Faucheu C, Lalanne JL, Diu A, Livingston DJ, Su MS: Interleukin-1 beta coverting enzyme requires oligomerization for activity. EMBO J 14:1923, 1995
43. Li P, Allen H, Banerjee S, Franklin S. Herzog L, Johnston C, McDowell J: Mice deficient in IL-1 beta-converting enzyme are defective in production. Cell 80:401, 1995
44. Faucheu C, Diu A, Chan AW, Blanchet AM, Miossec C, Herve F: A novel human protease similar to the interleukin-1 beta converting enzyme. EMBO J 14:1914, 1995
45. Enari M, Hug H, Nagata S: Involvement of an ICE-like protease in Fas-mediated apoptosis. Nature 375:78, 1995
46. Schlegel J, Peters I, Orrenius S, Miller DK, Thornberry NA, Yamin TT, Nicholson DW: CPP32/apopain is a key interleukin 1 beta converting enzyme-like protease involved in Fas-mediated apoptosis. J Biol Chem 271:1841,1996
47. Boldin MP, Gancharov TM, Goltsev YV, Wallach D: Involvement of MACH, a novel MORT1/FADD-interacting protease, in Fas/APO-1-and TNF receptor-induced cell death. Cell 85:803, 1996
48. Muzio M, Chinnaiyan AM, Kischkel FC, O'Rourke K, Schevchenko A, Ni J, Scaffidi C, Bretz JD, Zhang M, Gentz R, Mann M, Krammer PH, Peter ME, Dixit VM: FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death-inducing signaling complex. Cell 85:817, 1996
49. Armstrong RC, Aja T, Xiang J, Gaur S, Krebs JF, Hoang K, Bai X, Korsmeyer SJ, Karanewsky DS, Fritz LC, Tomaselli KJ: Fas-induced activation of the cell death-related protease CPP32 is inhibited by Bcl-2 and by ICE family protease inhibitors. J Biol Chem 271: 16850, 1996
50. Glynn JM, McElligott DL, Mosier BE: Apoptosis induced by HIV infection in H9 T cells is blocked by ICE-family protease inhibition but not by a Fas(CD95) antagonist. J Immunol 157:2754, 1996
51. Norimatsu M, Ono T, Aoki A, Ohishi K, Tamura Y: In-vivo induction of apoptosis in murine lymphocytes by bacterial lipopolysaccharides. J Med Microbiol 43:251, 1995
52. Yokochi T, Kato Y, Sugiyama T, Koide N, Morikawa A, Jiang GZ, Kawai M, Yoshida T, Fukada M, Takahashi K: Lipopolysaccharide induces apoptotic cell death of B memory cells and regulates B cell memory in antigen-nonspecific manner. FEMS Immunol Med Microbiol 15:1, 1996
53. Norimatsu M, Ono T, Aoki A, Ohishi K, Takahashi T, Watanabe G, Taya K, Sasamoto S, Tamura Y: Lipopolysaccharide-induced apoptosis in swine lymphocytes in vivo. Infect Immun 63:1122, 1995
54. Isogai E, Isogal H, Kimura K, Fujii N, Takagi S, Hirose K, Hayashi M: In vivo induction of apoptosis and immune responses in mice by administration of lipopolysaccharide from Porphyromonas gingivalis. Infect Immun 64:1461, 1996