Staphylococcus aureus α-hemolysin activates the NLRP3-inflammasome in human and mouse monocytic cells

PLoS ONE

Volumn 4, Issue 10, 2009, Pages

  Craven, Robin R ^a   Gao, Xi ^a   Allen, Irving C ^b   Gris, Denis ^b   Wardenburg, Juliane Bubeck ^c   McElvania TeKippe, Erin ^a   Ting, Jenny P ^a,b   Duncan, Joseph A ^a  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF NORTH CAROLINA   (United States)

^c UNIVERSITY OF CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA HEMOLYSIN; CRYOPYRIN; CYSTEINE PROTEINASE; HIGH MOBILITY GROUP B1 PROTEIN; INTERLEUKIN 18; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; NUCLEAR PROTEIN; BACTERIAL TOXIN; CARRIER PROTEIN; CIAS1 PROTEIN, MOUSE; HEMOLYSIN; NLRP3 PROTEIN, HUMAN; STAPHYLOCOCCAL ALPHA-TOXIN; STAPHYLOCOCCUS ALPHA TOXIN;

ANIMAL CELL; ARTICLE; BACTERIAL VIRULENCE; CELL ACTIVATION; CONTROLLED STUDY; CYTOKINE RELEASE; ENZYME ACTIVATION; HUMAN; HUMAN CELL; INFLAMMATION; INNATE IMMUNITY; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; MONOCYTE; NECROSIS; NONHUMAN; SIGNAL TRANSDUCTION; TISSUE NECROSIS; ANIMAL; BONE MARROW CELL; CYTOLOGY; METABOLISM; MOUSE; STAPHYLOCOCCUS AUREUS;

METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; MUS; STAPHYLOCOCCUS AUREUS;

ANIMALS; BACTERIAL TOXINS; BONE MARROW CELLS; CARRIER PROTEINS; CASPASE 1; HEMOLYSIN PROTEINS; HMGB1 PROTEIN; HUMANS; INFLAMMATION; INTERLEUKIN-18; INTERLEUKIN-1BETA; MICE; MONOCYTES; SIGNAL TRANSDUCTION; STAPHYLOCOCCUS AUREUS;

EID: 70449360107     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0007446     Document Type: Article

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