-
1
-
-
0028201732
-
Tolerance, danger, and the extended family
-
doi: 10.1146/annurev.immunol.12.1.991
-
Matzinger P. Tolerance, danger, and the extended family. Annu Rev Immunol (1994) 12:991-1045. doi: 10.1146/annurev.immunol.12.1.991
-
(1994)
Annu Rev Immunol
, vol.12
, pp. 991-1045
-
-
Matzinger, P.1
-
2
-
-
0024955886
-
Approaching the asymptote? Evolution and revolution in immunology
-
doi:10.1101/SQB.1989.054.01.003
-
Janeway CA Jr. Approaching the asymptote? Evolution and revolution in immunology. Cold Spring Harb Symp Quant Biol (1989) 54(Pt 1):1-13. doi:10.1101/SQB.1989.054.01.003
-
(1989)
Cold Spring Harb Symp Quant Biol
, vol.54
, Issue.PART 1
, pp. 1-13
-
-
Janeway Jr., C.A.1
-
3
-
-
75849117800
-
Inflammation and oncogenesis: a vicious connection
-
doi:10.1016/j.gde.2009.11.004
-
Grivennikov SI, Karin M. Inflammation and oncogenesis: a vicious connection. Curr Opin Genet Dev (2010) 20(1):65-71. doi:10.1016/j.gde.2009.11.004
-
(2010)
Curr Opin Genet Dev
, vol.20
, Issue.1
, pp. 65-71
-
-
Grivennikov, S.I.1
Karin, M.2
-
4
-
-
77950346282
-
Immunity, inflammation, and cancer
-
doi:10.1016/j.cell.2010.01.025
-
Grivennikov SI, Greten FR, Karin M. Immunity, inflammation, and cancer. Cell (2010) 140(6):883-99. doi:10.1016/j.cell.2010.01.025
-
(2010)
Cell
, vol.140
, Issue.6
, pp. 883-899
-
-
Grivennikov, S.I.1
Greten, F.R.2
Karin, M.3
-
5
-
-
0030902366
-
The prognostic significance of intratumoral natural killer cells in patients with colorectal carcinoma
-
doi:10.1002/(SICI)1097-0142(19970615)79:12<2320::AID-CNCR5>3.0.CO;2-P
-
Coca S, Perez-Piqueras J, Martinez D, Colmenarejo A, Saez MA, Vallejo C, et al. The prognostic significance of intratumoral natural killer cells in patients with colorectal carcinoma. Cancer (1997) 79(12):2320-8. doi:10.1002/(SICI)1097-0142(19970615)79:12<2320::AID-CNCR5>3.0.CO;2-P
-
(1997)
Cancer
, vol.79
, Issue.12
, pp. 2320-2328
-
-
Coca, S.1
Perez-Piqueras, J.2
Martinez, D.3
Colmenarejo, A.4
Saez, M.A.5
Vallejo, C.6
-
6
-
-
78650735879
-
Inflammation-induced tumorigenesis in the colon is regulated by caspase-1 and NLRC4
-
doi:10.1073/pnas.1016814108
-
Hu B, Elinav E, Huber S, Booth CJ, Strowig T, Jin C, et al. Inflammation-induced tumorigenesis in the colon is regulated by caspase-1 and NLRC4. Proc Natl Acad Sci U S A (2010) 107(50):21635-40. doi:10.1073/pnas.1016814108
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, Issue.50
, pp. 21635-21640
-
-
Hu, B.1
Elinav, E.2
Huber, S.3
Booth, C.J.4
Strowig, T.5
Jin, C.6
-
7
-
-
13244252271
-
Caspase-1 activator Ipaf is a p53-inducible gene involved in apoptosis
-
doi:10.1038/sj.onc.1208201
-
Sadasivam S, Gupta S, Radha V, Batta K, Kundu TK, Swarup G. Caspase-1 activator Ipaf is a p53-inducible gene involved in apoptosis. Oncogene (2005) 24(4):627-36. doi:10.1038/sj.onc.1208201
-
(2005)
Oncogene
, vol.24
, Issue.4
, pp. 627-636
-
-
Sadasivam, S.1
Gupta, S.2
Radha, V.3
Batta, K.4
Kundu, T.K.5
Swarup, G.6
-
8
-
-
79959221313
-
Inflammasome-mediated suppression of inflammation-induced colorectal cancer progression is mediated by direct regulation of epithelial cell proliferation
-
doi:10.4161/cc.10.12.16008
-
Hu B, Elinav E, Flavell RA. Inflammasome-mediated suppression of inflammation-induced colorectal cancer progression is mediated by direct regulation of epithelial cell proliferation. Cell Cycle (2011) 10(12):1936-9. doi:10.4161/cc.10.12.16008
-
(2011)
Cell Cycle
, vol.10
, Issue.12
, pp. 1936-1939
-
-
Hu, B.1
Elinav, E.2
Flavell, R.A.3
-
9
-
-
79957576718
-
NLRP6 inflammasome regulates colonic microbial ecology and risk for colitis
-
doi:10.1016/j.cell.2011.04.022
-
Elinav E, Strowig T, Kau AL, Henao-Mejia J, Thaiss CA, Booth CJ, et al. NLRP6 inflammasome regulates colonic microbial ecology and risk for colitis. Cell (2011) 145(5):745-57. doi:10.1016/j.cell.2011.04.022
-
(2011)
Cell
, vol.145
, Issue.5
, pp. 745-757
-
-
Elinav, E.1
Strowig, T.2
Kau, A.L.3
Henao-Mejia, J.4
Thaiss, C.A.5
Booth, C.J.6
-
10
-
-
84878971321
-
Microbiota-induced activation of epithelial IL-6 signaling links inflammasome-driven inflammation with transmissible cancer
-
doi:10.1073/pnas.1307575110
-
Hu B, Elinav E, Huber S, Strowig T, Hao L, Hafemann A, et al. Microbiota-induced activation of epithelial IL-6 signaling links inflammasome-driven inflammation with transmissible cancer. Proc Natl Acad Sci U S A (2013) 110(24):9862-7. doi:10.1073/pnas.1307575110
-
(2013)
Proc Natl Acad Sci U S A
, vol.110
, Issue.24
, pp. 9862-9867
-
-
Hu, B.1
Elinav, E.2
Huber, S.3
Strowig, T.4
Hao, L.5
Hafemann, A.6
-
11
-
-
79959369355
-
Nod-like receptor pyrin domain-containing protein 6 (NLRP6) controls epithelial self-renewal and colorectal carcinogenesis upon injury
-
doi:10.1073/pnas.1100981108
-
Normand S, Delanoye-Crespin A, Bressenot A, Huot L, Grandjean T, Peyrin-Biroulet L, et al. Nod-like receptor pyrin domain-containing protein 6 (NLRP6) controls epithelial self-renewal and colorectal carcinogenesis upon injury. Proc Natl Acad Sci U S A (2011) 108(23):9601-6. doi:10.1073/pnas.1100981108
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, Issue.23
, pp. 9601-9606
-
-
Normand, S.1
Delanoye-Crespin, A.2
Bressenot, A.3
Huot, L.4
Grandjean, T.5
Peyrin-Biroulet, L.6
-
12
-
-
79959540809
-
A functional role for Nlrp6 in intestinal inflammation and tumorigenesis
-
doi:10.4049/jimmunol.1100412
-
Chen GY, Liu M, Wang F, Bertin J, Nunez G. A functional role for Nlrp6 in intestinal inflammation and tumorigenesis. J Immunol (2011) 186(12):7187-94. doi:10.4049/jimmunol.1100412
-
(2011)
J Immunol
, vol.186
, Issue.12
, pp. 7187-7194
-
-
Chen, G.Y.1
Liu, M.2
Wang, F.3
Bertin, J.4
Nunez, G.5
-
13
-
-
77952303410
-
The NLRP3 inflammasome functions as a negative regulator of tumorigenesis during colitis-associated cancer
-
doi:10.1084/jem.20100050
-
Allen IC, TeKippe EM, Woodford RM, Uronis JM, Holl EK, Rogers AB, et al. The NLRP3 inflammasome functions as a negative regulator of tumorigenesis during colitis-associated cancer. J Exp Med (2010) 207(5):1045-56. doi:10.1084/jem.20100050
-
(2010)
J Exp Med
, vol.207
, Issue.5
, pp. 1045-1056
-
-
Allen, I.C.1
TeKippe, E.M.2
Woodford, R.M.3
Uronis, J.M.4
Holl, E.K.5
Rogers, A.B.6
-
14
-
-
78049488908
-
IL-18 production downstream of the Nlrp3 inflammasome confers protection against colorectal tumor formation
-
doi:10.4049/jimmunol.1002046
-
Zaki MH, Vogel P, Body-Malapel M, Lamkanfi M, Kanneganti TD. IL-18 production downstream of the Nlrp3 inflammasome confers protection against colorectal tumor formation. J Immunol (2010) 185(8):4912-20. doi:10.4049/jimmunol.1002046
-
(2010)
J Immunol
, vol.185
, Issue.8
, pp. 4912-4920
-
-
Zaki, M.H.1
Vogel, P.2
Body-Malapel, M.3
Lamkanfi, M.4
Kanneganti, T.D.5
-
15
-
-
84869206979
-
NLRP3 suppresses NK cell-mediated responses to carcinogen-induced tumors and metastases
-
doi:10.1158/0008-5472.CAN-12-0509
-
Chow MT, Sceneay J, Paget C, Wong CS, Duret H, Tschopp J, et al. NLRP3 suppresses NK cell-mediated responses to carcinogen-induced tumors and metastases. Cancer Res (2012) 72(22):5721-32. doi:10.1158/0008-5472.CAN-12-0509
-
(2012)
Cancer Res
, vol.72
, Issue.22
, pp. 5721-5732
-
-
Chow, M.T.1
Sceneay, J.2
Paget, C.3
Wong, C.S.4
Duret, H.5
Tschopp, J.6
-
16
-
-
81255189478
-
The NOD-like receptor NLRP12 attenuates colon inflammation and tumorigenesis
-
doi:10.1016/j.ccr.2011.10.022
-
Zaki MH, Vogel P, Malireddi RK, Body-Malapel M, Anand PK, Bertin J, et al. The NOD-like receptor NLRP12 attenuates colon inflammation and tumorigenesis. Cancer Cell (2011) 20(5):649-60. doi:10.1016/j.ccr.2011.10.022
-
(2011)
Cancer Cell
, vol.20
, Issue.5
, pp. 649-660
-
-
Zaki, M.H.1
Vogel, P.2
Malireddi, R.K.3
Body-Malapel, M.4
Anand, P.K.5
Bertin, J.6
-
17
-
-
84861460062
-
NLRP12 suppresses colon inflammation and tumorigenesis through the negative regulation of noncanonical NF-kappaB signaling
-
doi:10.1016/j.immuni.2012.03.012
-
Allen IC, Wilson JE, Schneider M, Lich JD, Roberts RA, Arthur JC, et al. NLRP12 suppresses colon inflammation and tumorigenesis through the negative regulation of noncanonical NF-kappaB signaling. Immunity (2012) 36(5):742-54. doi:10.1016/j.immuni.2012.03.012
-
(2012)
Immunity
, vol.36
, Issue.5
, pp. 742-754
-
-
Allen, I.C.1
Wilson, J.E.2
Schneider, M.3
Lich, J.D.4
Roberts, R.A.5
Arthur, J.C.6
-
18
-
-
77950362382
-
The inflammasomes
-
doi:10.1016/j.cell.2010.01.040
-
Schroder K, Tschopp J. The inflammasomes. Cell (2010) 140(6):821-32. doi:10.1016/j.cell.2010.01.040
-
(2010)
Cell
, vol.140
, Issue.6
, pp. 821-832
-
-
Schroder, K.1
Tschopp, J.2
-
19
-
-
17644396670
-
CATERPILLER: a novel gene family important in immunity, cell death, and diseases
-
doi:10.1146/annurev.immunol.23.021704.115616
-
Ting JP, Davis BK. CATERPILLER: a novel gene family important in immunity, cell death, and diseases. Annu Rev Immunol (2005) 23:387-414. doi:10.1146/annurev.immunol.23.021704.115616
-
(2005)
Annu Rev Immunol
, vol.23
, pp. 387-414
-
-
Ting, J.P.1
Davis, B.K.2
-
20
-
-
66749174867
-
The inflammasomes: guardians of the body
-
doi:10.1146/annurev.immunol.021908.132715
-
Martinon F, Mayor A, Tschopp J. The inflammasomes: guardians of the body. Annu Rev Immunol (2009) 27:229-65. doi:10.1146/annurev.immunol.021908.132715
-
(2009)
Annu Rev Immunol
, vol.27
, pp. 229-265
-
-
Martinon, F.1
Mayor, A.2
Tschopp, J.3
-
21
-
-
39149116674
-
NLR, the nucleotide-binding domain leucine-rich repeat containing gene family
-
doi:10.1016/j.coi.2008.01.003
-
Ye Z, Ting JP. NLR, the nucleotide-binding domain leucine-rich repeat containing gene family. Curr Opin Immunol (2008) 20(1):3-9. doi:10.1016/j.coi.2008.01.003
-
(2008)
Curr Opin Immunol
, vol.20
, Issue.1
, pp. 3-9
-
-
Ye, Z.1
Ting, J.P.2
-
22
-
-
70249138036
-
Cutting edge: NF-kappaB activating pattern recognition and cytokine receptors license NLRP3 inflammasome activation by regulating NLRP3 expression
-
doi:10.4049/jimmunol.0901363
-
Bauernfeind FG, Horvath G, Stutz A, Alnemri ES, MacDonald K, Speert D, et al. Cutting edge: NF-kappaB activating pattern recognition and cytokine receptors license NLRP3 inflammasome activation by regulating NLRP3 expression. J Immunol (2009) 183(2):787-91. doi:10.4049/jimmunol.0901363
-
(2009)
J Immunol
, vol.183
, Issue.2
, pp. 787-791
-
-
Bauernfeind, F.G.1
Horvath, G.2
Stutz, A.3
Alnemri, E.S.4
MacDonald, K.5
Speert, D.6
-
23
-
-
84870292233
-
Control of innate and adaptive immunity by the inflammasome
-
doi:10.1016/j.micinf.2012.07.007
-
Ciraci C, Janczy JR, Sutterwala FS, Cassel SL. Control of innate and adaptive immunity by the inflammasome. Microbes Infect (2012) 14(14):1263-70. doi:10.1016/j.micinf.2012.07.007
-
(2012)
Microbes Infect
, vol.14
, Issue.14
, pp. 1263-1270
-
-
Ciraci, C.1
Janczy, J.R.2
Sutterwala, F.S.3
Cassel, S.L.4
-
24
-
-
84857175933
-
Dectin-1 is an extracellular pathogen sensor for the induction and processing of IL-1beta via a noncanonical caspase-8 inflammasome
-
doi:10.1038/ni.2222
-
Gringhuis SI, Kaptein TM, Wevers BA, Theelen B, van der Vlist M, Boekhout T, et al. Dectin-1 is an extracellular pathogen sensor for the induction and processing of IL-1beta via a noncanonical caspase-8 inflammasome. Nat Immunol (2012) 13(3):246-54. doi:10.1038/ni.2222
-
(2012)
Nat Immunol
, vol.13
, Issue.3
, pp. 246-254
-
-
Gringhuis, S.I.1
Kaptein, T.M.2
Wevers, B.A.3
Theelen, B.4
van der Vlist, M.5
Boekhout, T.6
-
25
-
-
80455176839
-
Non-canonical inflammasome activation targets caspase-11
-
doi:10.1038/nature10558
-
Kayagaki N, Warming S, Lamkanfi M, Vande Walle L, Louie S, Dong J, et al. Non-canonical inflammasome activation targets caspase-11. Nature (2011) 479(7371):117-21. doi:10.1038/nature10558
-
(2011)
Nature
, vol.479
, Issue.7371
, pp. 117-121
-
-
Kayagaki, N.1
Warming, S.2
Lamkanfi, M.3
Vande Walle, L.4
Louie, S.5
Dong, J.6
-
26
-
-
67650151005
-
Cancer-related inflammation, the seventh hallmark of cancer: links to genetic instability
-
doi:10.1093/carcin/bgp127
-
Colotta F, Allavena P, Sica A, Garlanda C, Mantovani A. Cancer-related inflammation, the seventh hallmark of cancer: links to genetic instability. Carcinogenesis (2009) 30(7):1073-81. doi:10.1093/carcin/bgp127
-
(2009)
Carcinogenesis
, vol.30
, Issue.7
, pp. 1073-1081
-
-
Colotta, F.1
Allavena, P.2
Sica, A.3
Garlanda, C.4
Mantovani, A.5
-
27
-
-
79952284127
-
Hallmarks of cancer: the next generation
-
doi:10.1016/j.cell.2011.02.013
-
Hanahan D, Weinberg RA. Hallmarks of cancer: the next generation. Cell (2011) 144(5):646-74. doi:10.1016/j.cell.2011.02.013
-
(2011)
Cell
, vol.144
, Issue.5
, pp. 646-674
-
-
Hanahan, D.1
Weinberg, R.A.2
-
28
-
-
0035958867
-
Identification of Ipaf, a human caspase-1-activating protein related to Apaf-1
-
doi:10.1074/jbc.C100250200
-
Poyet JL, Srinivasula SM, Tnani M, Razmara M, Fernandes-Alnemri T, Alnemri ES. Identification of Ipaf, a human caspase-1-activating protein related to Apaf-1. J Biol Chem (2001) 276(30):28309-13. doi:10.1074/jbc.C100250200
-
(2001)
J Biol Chem
, vol.276
, Issue.30
, pp. 28309-28313
-
-
Poyet, J.L.1
Srinivasula, S.M.2
Tnani, M.3
Razmara, M.4
Fernandes-Alnemri, T.5
Alnemri, E.S.6
-
29
-
-
57149102672
-
NLRC4/IPAF: a CARD carrying member of the NLR family
-
doi:10.1016/j.clim.2008.08.011
-
Sutterwala FS, Flavell RA. NLRC4/IPAF: a CARD carrying member of the NLR family. Clin Immunol (2009) 130(1):2-6. doi:10.1016/j.clim.2008.08.011
-
(2009)
Clin Immunol
, vol.130
, Issue.1
, pp. 2-6
-
-
Sutterwala, F.S.1
Flavell, R.A.2
-
30
-
-
36248940773
-
Critical role for Ipaf in Pseudomonas aeruginosa-induced caspase-1 activation
-
doi:10.1002/eji.200737532
-
Franchi L, Stoolman J, Kanneganti TD, Verma A, Ramphal R, Nunez G. Critical role for Ipaf in Pseudomonas aeruginosa-induced caspase-1 activation. Eur J Immunol (2007) 37(11):3030-9. doi:10.1002/eji.200737532
-
(2007)
Eur J Immunol
, vol.37
, Issue.11
, pp. 3030-3039
-
-
Franchi, L.1
Stoolman, J.2
Kanneganti, T.D.3
Verma, A.4
Ramphal, R.5
Nunez, G.6
-
31
-
-
3142654767
-
Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf
-
doi:10.1038/nature02664
-
Mariathasan S, Newton K, Monack DM, Vucic D, French DM, Lee WP, et al. Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf. Nature (2004) 430(6996):213-8. doi:10.1038/nature02664
-
(2004)
Nature
, vol.430
, Issue.6996
, pp. 213-218
-
-
Mariathasan, S.1
Newton, K.2
Monack, D.M.3
Vucic, D.4
French, D.M.5
Lee, W.P.6
-
32
-
-
34548434775
-
Differential regulation of caspase-1 activation, pyroptosis, and autophagy via Ipaf and ASC in Shigella-infected macrophages
-
doi:10.1371/journal.ppat.0030111
-
Suzuki T, Franchi L, Toma C, Ashida H, Ogawa M, Yoshikawa Y, et al. Differential regulation of caspase-1 activation, pyroptosis, and autophagy via Ipaf and ASC in Shigella-infected macrophages. PLoS Pathog (2007) 3(8):e111. doi:10.1371/journal.ppat.0030111
-
(2007)
PLoS Pathog
, vol.3
, Issue.8
-
-
Suzuki, T.1
Franchi, L.2
Toma, C.3
Ashida, H.4
Ogawa, M.5
Yoshikawa, Y.6
-
33
-
-
36248968798
-
ASC/PYCARD and caspase-1 regulate the IL-18/IFN-gamma axis during Anaplasma phagocytophilum infection
-
Pedra JH, Sutterwala FS, Sukumaran B, Ogura Y, Qian F, Montgomery RR, et al. ASC/PYCARD and caspase-1 regulate the IL-18/IFN-gamma axis during Anaplasma phagocytophilum infection. J Immunol (2007) 179(7):4783-91.
-
(2007)
J Immunol
, vol.179
, Issue.7
, pp. 4783-4791
-
-
Pedra, J.H.1
Sutterwala, F.S.2
Sukumaran, B.3
Ogura, Y.4
Qian, F.5
Montgomery, R.R.6
-
34
-
-
37549041954
-
Immune recognition of Pseudomonas aeruginosa mediated by the IPAF/NLRC4 inflammasome
-
doi:10.1084/jem.20071239
-
Sutterwala FS, Mijares LA, Li L, Ogura Y, Kazmierczak BI, Flavell RA. Immune recognition of Pseudomonas aeruginosa mediated by the IPAF/NLRC4 inflammasome. J Exp Med (2007) 204(13):3235-45. doi:10.1084/jem.20071239
-
(2007)
J Exp Med
, vol.204
, Issue.13
, pp. 3235-3245
-
-
Sutterwala, F.S.1
Mijares, L.A.2
Li, L.3
Ogura, Y.4
Kazmierczak, B.I.5
Flavell, R.A.6
-
35
-
-
33645770203
-
The Birc1e cytosolic pattern-recognition receptor contributes to the detection and control of Legionella pneumophila infection
-
doi:10.1038/ni1305
-
Zamboni DS, Kobayashi KS, Kohlsdorf T, Ogura Y, Long EM, Vance RE, et al. The Birc1e cytosolic pattern-recognition receptor contributes to the detection and control of Legionella pneumophila infection. Nat Immunol (2006) 7(3):318-25. doi:10.1038/ni1305
-
(2006)
Nat Immunol
, vol.7
, Issue.3
, pp. 318-325
-
-
Zamboni, D.S.1
Kobayashi, K.S.2
Kohlsdorf, T.3
Ogura, Y.4
Long, E.M.5
Vance, R.E.6
-
36
-
-
33744464740
-
Cytosolic flagellin requires Ipaf for activation of caspase-1 and interleukin 1beta in Salmonella-infected macrophages
-
doi:10.1038/ni1346
-
Franchi L, Amer A, Body-Malapel M, Kanneganti TD, Ozoren N, Jagirdar R, et al. Cytosolic flagellin requires Ipaf for activation of caspase-1 and interleukin 1beta in Salmonella-infected macrophages. Nat Immunol (2006) 7(6):576-82. doi:10.1038/ni1346
-
(2006)
Nat Immunol
, vol.7
, Issue.6
, pp. 576-582
-
-
Franchi, L.1
Amer, A.2
Body-Malapel, M.3
Kanneganti, T.D.4
Ozoren, N.5
Jagirdar, R.6
-
37
-
-
33744493091
-
Cytoplasmic flagellin activates caspase-1 and secretion of interleukin 1beta via Ipaf
-
doi:10.1038/ni1344
-
Miao EA, Alpuche-Aranda CM, Dors M, Clark AE, Bader MW, Miller SI, et al. Cytoplasmic flagellin activates caspase-1 and secretion of interleukin 1beta via Ipaf. Nat Immunol (2006) 7(6):569-75. doi:10.1038/ni1344
-
(2006)
Nat Immunol
, vol.7
, Issue.6
, pp. 569-575
-
-
Miao, E.A.1
Alpuche-Aranda, C.M.2
Dors, M.3
Clark, A.E.4
Bader, M.W.5
Miller, S.I.6
-
38
-
-
77649241461
-
Innate immune detection of the type III secretion apparatus through the NLRC4 inflammasome
-
doi:10.1073/pnas.0913087107
-
Miao EA, Mao DP, Yudkovsky N, Bonneau R, Lorang CG, Warren SE, et al. Innate immune detection of the type III secretion apparatus through the NLRC4 inflammasome. Proc Natl Acad Sci U S A (2010) 107(7):3076-80. doi:10.1073/pnas.0913087107
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, Issue.7
, pp. 3076-3080
-
-
Miao, E.A.1
Mao, D.P.2
Yudkovsky, N.3
Bonneau, R.4
Lorang, C.G.5
Warren, S.E.6
-
39
-
-
52549099416
-
Critical function for Naip5 in inflammasome activation by a conserved carboxy-terminal domain of flagellin
-
doi:10.1038/ni.1646
-
Lightfield KL, Persson J, Brubaker SW, Witte CE, von Moltke J, Dunipace EA, et al. Critical function for Naip5 in inflammasome activation by a conserved carboxy-terminal domain of flagellin. Nat Immunol (2008) 9(10):1171-8. doi:10.1038/ni.1646
-
(2008)
Nat Immunol
, vol.9
, Issue.10
, pp. 1171-1178
-
-
Lightfield, K.L.1
Persson, J.2
Brubaker, S.W.3
Witte, C.E.4
von Moltke, J.5
Dunipace, E.A.6
-
40
-
-
79953315378
-
Differential requirements for NAIP5 in activation of the NLRC4 inflammasome
-
doi:10.1128/IAI.01187-10
-
Lightfield KL, Persson J, Trinidad NJ, Brubaker SW, Kofoed EM, Sauer JD, et al. Differential requirements for NAIP5 in activation of the NLRC4 inflammasome. Infect Immun (2011) 79(4):1606-14. doi:10.1128/IAI.01187-10
-
(2011)
Infect Immun
, vol.79
, Issue.4
, pp. 1606-1614
-
-
Lightfield, K.L.1
Persson, J.2
Trinidad, N.J.3
Brubaker, S.W.4
Kofoed, E.M.5
Sauer, J.D.6
-
41
-
-
80053349020
-
The NLRC4 inflammasome receptors for bacterial flagellin and type III secretion apparatus
-
doi:10.1038/nature10510
-
Zhao Y, Yang J, Shi J, Gong YN, Lu Q, Xu H, et al. The NLRC4 inflammasome receptors for bacterial flagellin and type III secretion apparatus. Nature (2011) 477(7366):596-600. doi:10.1038/nature10510
-
(2011)
Nature
, vol.477
, Issue.7366
, pp. 596-600
-
-
Zhao, Y.1
Yang, J.2
Shi, J.3
Gong, Y.N.4
Lu, Q.5
Xu, H.6
-
42
-
-
21244460672
-
Naip5/Birc1e and susceptibility to Legionella pneumophila
-
doi:10.1016/j.tim.2005.05.007
-
Fortier A, Diez E, Gros P. Naip5/Birc1e and susceptibility to Legionella pneumophila. Trends Microbiol (2005) 13(7):328-35. doi:10.1016/j.tim.2005.05.007
-
(2005)
Trends Microbiol
, vol.13
, Issue.7
, pp. 328-335
-
-
Fortier, A.1
Diez, E.2
Gros, P.3
-
43
-
-
84856988610
-
Simultaneous targeting of toll-and nod-like receptors induces effective tumor-specific immune responses
-
doi:10.1126/scitranslmed.3002868
-
Garaude J, Kent A, van Rooijen N, Blander JM. Simultaneous targeting of toll-and nod-like receptors induces effective tumor-specific immune responses. Sci Transl Med (2012) 4(120):120ra16. doi:10.1126/scitranslmed.3002868
-
(2012)
Sci Transl Med
, vol.4
, Issue.120
-
-
Garaude, J.1
Kent, A.2
van Rooijen, N.3
Blander, J.M.4
-
44
-
-
84859911615
-
NLRC4-driven production of IL-1beta discriminates between pathogenic and commensal bacteria and promotes host intestinal defense
-
doi:10.1038/ni.2263
-
Franchi L, Kamada N, Nakamura Y, Burberry A, Kuffa P, Suzuki S, et al. NLRC4-driven production of IL-1beta discriminates between pathogenic and commensal bacteria and promotes host intestinal defense. Nat Immunol (2012) 13(5):449-56. doi:10.1038/ni.2263
-
(2012)
Nat Immunol
, vol.13
, Issue.5
, pp. 449-456
-
-
Franchi, L.1
Kamada, N.2
Nakamura, Y.3
Burberry, A.4
Kuffa, P.5
Suzuki, S.6
-
45
-
-
84862682110
-
The three main stumbling blocks for anticancer T cells
-
doi:10.1016/j.it.2012.02.006
-
Baitsch L, Fuertes-Marraco SA, Legat A, Meyer C, Speiser DE. The three main stumbling blocks for anticancer T cells. Trends Immunol (2012) 33(7):364-72. doi:10.1016/j.it.2012.02.006
-
(2012)
Trends Immunol
, vol.33
, Issue.7
, pp. 364-372
-
-
Baitsch, L.1
Fuertes-Marraco, S.A.2
Legat, A.3
Meyer, C.4
Speiser, D.E.5
-
46
-
-
18644368579
-
Functional screening of five PYPAF family members identifies PYPAF5 as a novel regulator of NF-kappaB and caspase-1
-
doi:10.1016/S0014-5793(02)03416-6
-
Grenier JM, Wang L, Manji GA, Huang WJ, Al-Garawi A, Kelly R, et al. Functional screening of five PYPAF family members identifies PYPAF5 as a novel regulator of NF-kappaB and caspase-1. FEBS Lett (2002) 530(1-3):73-8. doi:10.1016/S0014-5793(02)03416-6
-
(2002)
FEBS Lett
, vol.530
, Issue.1-3
, pp. 73-78
-
-
Grenier, J.M.1
Wang, L.2
Manji, G.A.3
Huang, W.J.4
Al-Garawi, A.5
Kelly, R.6
-
47
-
-
84865130689
-
NLRP6 negatively regulates innate immunity and host defence against bacterial pathogens
-
doi:10.1038/nature11250
-
Anand PK, Malireddi RK, Lukens JR, Vogel P, Bertin J, Lamkanfi M, et al. NLRP6 negatively regulates innate immunity and host defence against bacterial pathogens. Nature (2012) 488(7411):389-93. doi:10.1038/nature11250
-
(2012)
Nature
, vol.488
, Issue.7411
, pp. 389-393
-
-
Anand, P.K.1
Malireddi, R.K.2
Lukens, J.R.3
Vogel, P.4
Bertin, J.5
Lamkanfi, M.6
-
48
-
-
0036741464
-
Mucosal and invading bacteria in patients with inflammatory bowel disease compared with controls
-
doi:10.1080/003655202320378220
-
Kleessen B, Kroesen AJ, Buhr HJ, Blaut M. Mucosal and invading bacteria in patients with inflammatory bowel disease compared with controls. Scand J Gastroenterol (2002) 37(9):1034-41. doi:10.1080/003655202320378220
-
(2002)
Scand J Gastroenterol
, vol.37
, Issue.9
, pp. 1034-1041
-
-
Kleessen, B.1
Kroesen, A.J.2
Buhr, H.J.3
Blaut, M.4
-
49
-
-
33646241058
-
Prevalence of Bacteroides and Prevotella spp. in ulcerative colitis
-
doi:10.1099/jmm.0.46198-0
-
Lucke K, Miehlke S, Jacobs E, Schuppler M. Prevalence of Bacteroides and Prevotella spp. in ulcerative colitis. J Med Microbiol (2006) 55(Pt 5):617-24. doi:10.1099/jmm.0.46198-0
-
(2006)
J Med Microbiol
, vol.55
, Issue.PART 5
, pp. 617-624
-
-
Lucke, K.1
Miehlke, S.2
Jacobs, E.3
Schuppler, M.4
-
50
-
-
79551571717
-
Microbial dysbiosis in colorectal cancer (CRC) patients
-
doi:10.1371/journal.pone.0016393
-
Sobhani I, Tap J, Roudot-Thoraval F, Roperch JP, Letulle S, Langella P, et al. Microbial dysbiosis in colorectal cancer (CRC) patients. PLoS One (2011) 6(1):e16393. doi:10.1371/journal.pone.0016393
-
(2011)
PLoS One
, vol.6
, Issue.1
-
-
Sobhani, I.1
Tap, J.2
Roudot-Thoraval, F.3
Roperch, J.P.4
Letulle, S.5
Langella, P.6
-
51
-
-
79951818190
-
Differential expression of NLRP3 among hematopoietic cells
-
doi:10.4049/jimmunol.1002720
-
Guarda G, Zenger M, Yazdi AS, Schroder K, Ferrero I, Menu P, et al. Differential expression of NLRP3 among hematopoietic cells. J Immunol (2011) 186(4):2529-34. doi:10.4049/jimmunol.1002720
-
(2011)
J Immunol
, vol.186
, Issue.4
, pp. 2529-2534
-
-
Guarda, G.1
Zenger, M.2
Yazdi, A.S.3
Schroder, K.4
Ferrero, I.5
Menu, P.6
-
52
-
-
77950002937
-
The NLRP3 inflammasome protects against loss of epithelial integrity and mortality during experimental colitis
-
doi:10.1016/j.immuni.2010.03.003
-
Zaki MH, Boyd KL, Vogel P, Kastan MB, Lamkanfi M, Kanneganti TD. The NLRP3 inflammasome protects against loss of epithelial integrity and mortality during experimental colitis. Immunity (2010) 32(3):379-91. doi:10.1016/j.immuni.2010.03.003
-
(2010)
Immunity
, vol.32
, Issue.3
, pp. 379-391
-
-
Zaki, M.H.1
Boyd, K.L.2
Vogel, P.3
Kastan, M.B.4
Lamkanfi, M.5
Kanneganti, T.D.6
-
53
-
-
67349271142
-
Syk kinase signalling couples to the Nlrp3 inflammasome for anti-fungal host defence
-
doi:10.1038/nature07965
-
Gross O, Poeck H, Bscheider M, Dostert C, Hannesschlager N, Endres S, et al. Syk kinase signalling couples to the Nlrp3 inflammasome for anti-fungal host defence. Nature (2009) 459(7245):433-6. doi:10.1038/nature07965
-
(2009)
Nature
, vol.459
, Issue.7245
, pp. 433-436
-
-
Gross, O.1
Poeck, H.2
Bscheider, M.3
Dostert, C.4
Hannesschlager, N.5
Endres, S.6
-
54
-
-
33846014297
-
Critical role for cryopyrin/Nalp3 in activation of caspase-1 in response to viral infection and double-stranded RNA
-
doi:10.1074/jbc.M607594200
-
Kanneganti TD, Body-Malapel M, Amer A, Park JH, Whitfield J, Franchi L, et al. Critical role for cryopyrin/Nalp3 in activation of caspase-1 in response to viral infection and double-stranded RNA. J Biol Chem (2006) 281(48):36560-8. doi:10.1074/jbc.M607594200
-
(2006)
J Biol Chem
, vol.281
, Issue.48
, pp. 36560-36568
-
-
Kanneganti, T.D.1
Body-Malapel, M.2
Amer, A.3
Park, J.H.4
Whitfield, J.5
Franchi, L.6
-
55
-
-
32944470765
-
Cryopyrin activates the inflammasome in response to toxins and ATP
-
doi:10.1038/nature04515
-
Mariathasan S, Weiss DS, Newton K, McBride J, O'Rourke K, Roose-Girma M, et al. Cryopyrin activates the inflammasome in response to toxins and ATP. Nature (2006) 440(7081):228-32. doi:10.1038/nature04515
-
(2006)
Nature
, vol.440
, Issue.7081
, pp. 228-232
-
-
Mariathasan, S.1
Weiss, D.S.2
Newton, K.3
McBride, J.4
O'Rourke, K.5
Roose-Girma, M.6
-
56
-
-
65649140025
-
Uric acid is a danger signal activating NALP3 inflammasome in lung injury inflammation and fibrosis
-
doi:10.1164/rccm.200808-1274OC
-
Gasse P, Riteau N, Charron S, Girre S, Fick L, Petrilli V, et al. Uric acid is a danger signal activating NALP3 inflammasome in lung injury inflammation and fibrosis. Am J Respir Crit Care Med (2009) 179(10):903-13. doi:10.1164/rccm.200808-1274OC
-
(2009)
Am J Respir Crit Care Med
, vol.179
, Issue.10
, pp. 903-913
-
-
Gasse, P.1
Riteau, N.2
Charron, S.3
Girre, S.4
Fick, L.5
Petrilli, V.6
-
57
-
-
32944468985
-
Gout-associated uric acid crystals activate the NALP3 inflammasome
-
doi:10.1038/nature04516
-
Martinon F, Petrilli V, Mayor A, Tardivel A, Tschopp J. Gout-associated uric acid crystals activate the NALP3 inflammasome. Nature (2006) 440(7081):237-41. doi:10.1038/nature04516
-
(2006)
Nature
, vol.440
, Issue.7081
, pp. 237-241
-
-
Martinon, F.1
Petrilli, V.2
Mayor, A.3
Tardivel, A.4
Tschopp, J.5
-
58
-
-
47849132947
-
The Nalp3 inflammasome is essential for the development of silicosis
-
doi:10.1073/pnas.0803933105
-
Cassel SL, Eisenbarth SC, Iyer SS, Sadler JJ, Colegio OR, Tephly LA, et al. The Nalp3 inflammasome is essential for the development of silicosis. Proc Natl Acad Sci U S A (2008) 105(26):9035-40. doi:10.1073/pnas.0803933105
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, Issue.26
, pp. 9035-9040
-
-
Cassel, S.L.1
Eisenbarth, S.C.2
Iyer, S.S.3
Sadler, J.J.4
Colegio, O.R.5
Tephly, L.A.6
-
59
-
-
43249125839
-
Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica
-
doi:10.1126/science.1156995
-
Dostert C, Petrilli V, Van Bruggen R, Steele C, Mossman BT, Tschopp J. Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica. Science (2008) 320(5876):674-7. doi:10.1126/science.1156995
-
(2008)
Science
, vol.320
, Issue.5876
, pp. 674-677
-
-
Dostert, C.1
Petrilli, V.2
Van Bruggen, R.3
Steele, C.4
Mossman, B.T.5
Tschopp, J.6
-
60
-
-
47849097202
-
Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization
-
doi:10.1038/ni.1631
-
Hornung V, Bauernfeind F, Halle A, Samstad EO, Kono H, Rock KL, et al. Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization. Nat Immunol (2008) 9(8):847-56. doi:10.1038/ni.1631
-
(2008)
Nat Immunol
, vol.9
, Issue.8
, pp. 847-856
-
-
Hornung, V.1
Bauernfeind, F.2
Halle, A.3
Samstad, E.O.4
Kono, H.5
Rock, K.L.6
-
61
-
-
79951642032
-
Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome
-
doi:10.1038/ni.1980
-
Nakahira K, Haspel JA, Rathinam VA, Lee SJ, Dolinay T, Lam HC, et al. Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome. Nat Immunol (2011) 12(3):222-30. doi:10.1038/ni.1980
-
(2011)
Nat Immunol
, vol.12
, Issue.3
, pp. 222-230
-
-
Nakahira, K.1
Haspel, J.A.2
Rathinam, V.A.3
Lee, S.J.4
Dolinay, T.5
Lam, H.C.6
-
62
-
-
78651393239
-
A role for mitochondria in NLRP3 inflammasome activation
-
doi:10.1038/nature09663
-
Zhou R, Yazdi AS, Menu P, Tschopp J. A role for mitochondria in NLRP3 inflammasome activation. Nature (2011) 469(7329):221-5. doi:10.1038/nature09663
-
(2011)
Nature
, vol.469
, Issue.7329
, pp. 221-225
-
-
Zhou, R.1
Yazdi, A.S.2
Menu, P.3
Tschopp, J.4
-
63
-
-
34548027736
-
Activation of the NALP3 inflammasome is triggered by low intracellular potassium concentration
-
doi:10.1038/sj.cdd.4402195
-
Petrilli V, Papin S, Dostert C, Mayor A, Martinon F, Tschopp J. Activation of the NALP3 inflammasome is triggered by low intracellular potassium concentration. Cell Death Differ (2007) 14(9):1583-9. doi:10.1038/sj.cdd.4402195
-
(2007)
Cell Death Differ
, vol.14
, Issue.9
, pp. 1583-1589
-
-
Petrilli, V.1
Papin, S.2
Dostert, C.3
Mayor, A.4
Martinon, F.5
Tschopp, J.6
-
64
-
-
84870508924
-
The calcium-sensing receptor regulates the NLRP3 inflammasome through Ca2+ and cAMP
-
doi:10.1038/nature11588
-
Lee GS, Subramanian N, Kim AI, Aksentijevich I, Goldbach-Mansky R, Sacks DB, et al. The calcium-sensing receptor regulates the NLRP3 inflammasome through Ca2+ and cAMP. Nature (2012) 492(7427):123-7. doi:10.1038/nature11588
-
(2012)
Nature
, vol.492
, Issue.7427
, pp. 123-127
-
-
Lee, G.S.1
Subramanian, N.2
Kim, A.I.3
Aksentijevich, I.4
Goldbach-Mansky, R.5
Sacks, D.B.6
-
65
-
-
84875908991
-
TRPM2 links oxidative stress to NLRP3 inflammasome activation
-
doi:10.1038/ncomms2608
-
Zhong Z, Zhai Y, Liang S, Mori Y, Han R, Sutterwala FS, et al. TRPM2 links oxidative stress to NLRP3 inflammasome activation. Nat Commun (2013) 4:1611. doi:10.1038/ncomms2608
-
(2013)
Nat Commun
, vol.4
, pp. 1611
-
-
Zhong, Z.1
Zhai, Y.2
Liang, S.3
Mori, Y.4
Han, R.5
Sutterwala, F.S.6
-
66
-
-
70350569295
-
Activation of the NLRP3 inflammasome in dendritic cells induces IL-1beta-dependent adaptive immunity against tumors
-
doi:10.1038/nm.2028
-
Ghiringhelli F, Apetoh L, Tesniere A, Aymeric L, Ma Y, Ortiz C, et al. Activation of the NLRP3 inflammasome in dendritic cells induces IL-1beta-dependent adaptive immunity against tumors. Nat Med (2009) 15(10):1170-8. doi:10.1038/nm.2028
-
(2009)
Nat Med
, vol.15
, Issue.10
, pp. 1170-1178
-
-
Ghiringhelli, F.1
Apetoh, L.2
Tesniere, A.3
Aymeric, L.4
Ma, Y.5
Ortiz, C.6
-
67
-
-
84872086179
-
Chemotherapy-triggered cathepsin B release in myeloid-derived suppressor cells activates the Nlrp3 inflammasome and promotes tumor growth
-
doi:10.1038/nm.2999
-
Bruchard M, Mignot G, Derangere V, Chalmin F, Chevriaux A, Vegran F, et al. Chemotherapy-triggered cathepsin B release in myeloid-derived suppressor cells activates the Nlrp3 inflammasome and promotes tumor growth. Nat Med (2013) 19(1):57-64. doi:10.1038/nm.2999
-
(2013)
Nat Med
, vol.19
, Issue.1
, pp. 57-64
-
-
Bruchard, M.1
Mignot, G.2
Derangere, V.3
Chalmin, F.4
Chevriaux, A.5
Vegran, F.6
-
68
-
-
84869009687
-
How cancer metabolism is tuned for proliferation and vulnerable to disruption
-
doi:10.1038/nature11706
-
Schulze A, Harris AL. How cancer metabolism is tuned for proliferation and vulnerable to disruption. Nature (2012) 491(7424):364-73. doi:10.1038/nature11706
-
(2012)
Nature
, vol.491
, Issue.7424
, pp. 364-373
-
-
Schulze, A.1
Harris, A.L.2
-
69
-
-
77952737658
-
Mitochondrial metabolism and ROS generation are essential for Kras-mediated tumorigenicity
-
doi:10.1073/pnas.1003428107
-
Weinberg F, Hamanaka R, Wheaton WW, Weinberg S, Joseph J, Lopez M, et al. Mitochondrial metabolism and ROS generation are essential for Kras-mediated tumorigenicity. Proc Natl Acad Sci U S A (2010) 107(19):8788-93. doi:10.1073/pnas.1003428107
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, Issue.19
, pp. 8788-8793
-
-
Weinberg, F.1
Hamanaka, R.2
Wheaton, W.W.3
Weinberg, S.4
Joseph, J.5
Lopez, M.6
-
70
-
-
77949965210
-
Control of intestinal homeostasis, colitis, and colitis-associated colorectal cancer by the inflammatory caspases
-
doi:10.1016/j.immuni.2010.02.012
-
Dupaul-Chicoine J, Yeretssian G, Doiron K, Bergstrom KS, McIntire CR, LeBlanc PM, et al. Control of intestinal homeostasis, colitis, and colitis-associated colorectal cancer by the inflammatory caspases. Immunity (2010) 32(3):367-78. doi:10.1016/j.immuni.2010.02.012
-
(2010)
Immunity
, vol.32
, Issue.3
, pp. 367-378
-
-
Dupaul-Chicoine, J.1
Yeretssian, G.2
Doiron, K.3
Bergstrom, K.S.4
McIntire, C.R.5
LeBlanc, P.M.6
-
71
-
-
77955350419
-
MyD88-mediated signaling prevents development of adenocarcinomas of the colon: role of interleukin 18
-
doi:10.1084/jem.20100199
-
Salcedo R, Worschech A, Cardone M, Jones Y, Gyulai Z, Dai RM, et al. MyD88-mediated signaling prevents development of adenocarcinomas of the colon: role of interleukin 18. J Exp Med (2010) 207(8):1625-36. doi:10.1084/jem.20100199
-
(2010)
J Exp Med
, vol.207
, Issue.8
, pp. 1625-1636
-
-
Salcedo, R.1
Worschech, A.2
Cardone, M.3
Jones, Y.4
Gyulai, Z.5
Dai, R.M.6
-
72
-
-
70350500225
-
STATs in cancer inflammation and immunity: a leading role for STAT3
-
doi:10.1038/nrc2734
-
Yu H, Pardoll D, Jove R. STATs in cancer inflammation and immunity: a leading role for STAT3. Nat Rev Cancer (2009) 9(11):798-809. doi:10.1038/nrc2734
-
(2009)
Nat Rev Cancer
, vol.9
, Issue.11
, pp. 798-809
-
-
Yu, H.1
Pardoll, D.2
Jove, R.3
-
73
-
-
77949889567
-
Constitutively active inflammasome in human melanoma cells mediating autoinflammation via caspase-1 processing and secretion of interleukin-1beta
-
doi:10.1074/jbc.M109.064907
-
Okamoto M, Liu W, Luo Y, Tanaka A, Cai X, Norris DA, et al. Constitutively active inflammasome in human melanoma cells mediating autoinflammation via caspase-1 processing and secretion of interleukin-1beta. J Biol Chem (2010) 285(9):6477-88. doi:10.1074/jbc.M109.064907
-
(2010)
J Biol Chem
, vol.285
, Issue.9
, pp. 6477-6488
-
-
Okamoto, M.1
Liu, W.2
Luo, Y.3
Tanaka, A.4
Cai, X.5
Norris, D.A.6
-
74
-
-
25144466458
-
Gemcitabine selectively eliminates splenic Gr-1+/CD11b+ myeloid suppressor cells in tumor-bearing animals and enhances antitumor immune activity
-
doi:10.1158/1078-0432.CCR-05-0883
-
Suzuki E, Kapoor V, Jassar AS, Kaiser LR, Albelda SM. Gemcitabine selectively eliminates splenic Gr-1+/CD11b+ myeloid suppressor cells in tumor-bearing animals and enhances antitumor immune activity. Clin Cancer Res (2005) 11(18):6713-21. doi:10.1158/1078-0432.CCR-05-0883
-
(2005)
Clin Cancer Res
, vol.11
, Issue.18
, pp. 6713-6721
-
-
Suzuki, E.1
Kapoor, V.2
Jassar, A.S.3
Kaiser, L.R.4
Albelda, S.M.5
-
75
-
-
77951086882
-
5-Fluorouracil selectively kills tumor-associated myeloid-derived suppressor cells resulting in enhanced T cell-dependent antitumor immunity
-
doi:10.1158/0008-5472.CAN-09-3690
-
Vincent J, Mignot G, Chalmin F, Ladoire S, Bruchard M, Chevriaux A, et al. 5-Fluorouracil selectively kills tumor-associated myeloid-derived suppressor cells resulting in enhanced T cell-dependent antitumor immunity. Cancer Res (2010) 70(8):3052-61. doi:10.1158/0008-5472.CAN-09-3690
-
(2010)
Cancer Res
, vol.70
, Issue.8
, pp. 3052-3061
-
-
Vincent, J.1
Mignot, G.2
Chalmin, F.3
Ladoire, S.4
Bruchard, M.5
Chevriaux, A.6
-
76
-
-
78650360196
-
The inflammasome component NLRP3 impairs antitumor vaccine by enhancing the accumulation of tumor-associated myeloid-derived suppressor cells
-
doi:10.1158/0008-5472.CAN-10-1921
-
van Deventer HW, Burgents JE, Wu QP, Woodford RM, Brickey WJ, Allen IC, et al. The inflammasome component NLRP3 impairs antitumor vaccine by enhancing the accumulation of tumor-associated myeloid-derived suppressor cells. Cancer Res (2010) 70(24):10161-9. doi:10.1158/0008-5472.CAN-10-1921
-
(2010)
Cancer Res
, vol.70
, Issue.24
, pp. 10161-10169
-
-
van Deventer, H.W.1
Burgents, J.E.2
Wu, Q.P.3
Woodford, R.M.4
Brickey, W.J.5
Allen, I.C.6
-
77
-
-
61349100687
-
Myeloid-derived suppressor cells as regulators of the immune system
-
doi:10.1038/nri2506
-
Gabrilovich DI, Nagaraj S. Myeloid-derived suppressor cells as regulators of the immune system. Nat Rev Immunol (2009) 9(3):162-74. doi:10.1038/nri2506
-
(2009)
Nat Rev Immunol
, vol.9
, Issue.3
, pp. 162-174
-
-
Gabrilovich, D.I.1
Nagaraj, S.2
-
78
-
-
80054849114
-
The NLRP12 pyrin domain: structure, dynamics, and functional insights
-
doi:10.1016/j.jmb.2011.09.024
-
Pinheiro AS, Eibl C, Ekman-Vural Z, Schwarzenbacher R, Peti W. The NLRP12 pyrin domain: structure, dynamics, and functional insights. J Mol Biol (2011) 413(4):790-803. doi:10.1016/j.jmb.2011.09.024
-
(2011)
J Mol Biol
, vol.413
, Issue.4
, pp. 790-803
-
-
Pinheiro, A.S.1
Eibl, C.2
Ekman-Vural, Z.3
Schwarzenbacher, R.4
Peti, W.5
-
79
-
-
0010464874
-
PYPAF7, a novel PYRIN-containing Apaf1-like protein that regulates activation of NF-kappa B and caspase-1-dependent cytokine processing
-
doi:10.1074/jbc.M203915200
-
Wang L, Manji GA, Grenier JM, Al-Garawi A, Merriam S, Lora JM, et al. PYPAF7, a novel PYRIN-containing Apaf1-like protein that regulates activation of NF-kappa B and caspase-1-dependent cytokine processing. J Biol Chem (2002) 277(33):29874-80. doi:10.1074/jbc.M203915200
-
(2002)
J Biol Chem
, vol.277
, Issue.33
, pp. 29874-29880
-
-
Wang, L.1
Manji, G.A.2
Grenier, J.M.3
Al-Garawi, A.4
Merriam, S.5
Lora, J.M.6
-
80
-
-
84875935843
-
Characterization of NLRP12 during the in vivo host immune response to Klebsiella pneumoniae and Mycobacterium tuberculosis
-
doi:10.1371/journal.pone.0060842
-
Allen IC, McElvania-Tekippe E, Wilson JE, Lich JD, Arthur JC, Sullivan JT, et al. Characterization of NLRP12 during the in vivo host immune response to Klebsiella pneumoniae and Mycobacterium tuberculosis. PLoS One (2013) 8(4):e60842. doi:10.1371/journal.pone.0060842
-
(2013)
PLoS One
, vol.8
, Issue.4
-
-
Allen, I.C.1
McElvania-Tekippe, E.2
Wilson, J.E.3
Lich, J.D.4
Arthur, J.C.5
Sullivan, J.T.6
-
81
-
-
33846473862
-
Monarch-1 suppresses non-canonical NF-kappaB activation and p52-dependent chemokine expression in monocytes
-
Lich JD, Williams KL, Moore CB, Arthur JC, Davis BK, Taxman DJ, et al. Monarch-1 suppresses non-canonical NF-kappaB activation and p52-dependent chemokine expression in monocytes. J Immunol (2007) 178(3):1256-60.
-
(2007)
J Immunol
, vol.178
, Issue.3
, pp. 1256-1260
-
-
Lich, J.D.1
Williams, K.L.2
Moore, C.B.3
Arthur, J.C.4
Davis, B.K.5
Taxman, D.J.6
-
82
-
-
40349113175
-
Mutations in NALP12 cause hereditary periodic fever syndromes
-
doi:10.1073/pnas.0708616105
-
Jeru I, Duquesnoy P, Fernandes-Alnemri T, Cochet E, Yu JW, Lackmy-Port-Lis M, et al. Mutations in NALP12 cause hereditary periodic fever syndromes. Proc Natl Acad Sci U S A (2008) 105(5):1614-9. doi:10.1073/pnas.0708616105
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, Issue.5
, pp. 1614-1619
-
-
Jeru, I.1
Duquesnoy, P.2
Fernandes-Alnemri, T.3
Cochet, E.4
Yu, J.W.5
Lackmy-Port-Lis, M.6
-
83
-
-
79955566751
-
Identification and functional consequences of a recurrent NLRP12 missense mutation in periodic fever syndromes
-
doi:10.1002/art.30241
-
Jeru I, Le Borgne G, Cochet E, Hayrapetyan H, Duquesnoy P, Grateau G, et al. Identification and functional consequences of a recurrent NLRP12 missense mutation in periodic fever syndromes. Arthritis Rheum (2011) 63(5):1459-64. doi:10.1002/art.30241
-
(2011)
Arthritis Rheum
, vol.63
, Issue.5
, pp. 1459-1464
-
-
Jeru, I.1
Le Borgne, G.2
Cochet, E.3
Hayrapetyan, H.4
Duquesnoy, P.5
Grateau, G.6
-
84
-
-
79953702540
-
Clinical presentation and pathogenesis of cold-induced autoinflammatory disease in a family with recurrence of an NLRP12 mutation
-
doi:10.1002/art.30170
-
Borghini S, Tassi S, Chiesa S, Caroli F, Carta S, Caorsi R, et al. Clinical presentation and pathogenesis of cold-induced autoinflammatory disease in a family with recurrence of an NLRP12 mutation. Arthritis Rheum (2011) 63(3):830-9. doi:10.1002/art.30170
-
(2011)
Arthritis Rheum
, vol.63
, Issue.3
, pp. 830-839
-
-
Borghini, S.1
Tassi, S.2
Chiesa, S.3
Caroli, F.4
Carta, S.5
Caorsi, R.6
-
85
-
-
84864317101
-
The NLRP12 inflammasome recognizes Yersinia pestis
-
doi:10.1016/j.immuni.2012.07.006
-
Vladimer GI, Weng D, Paquette SW, Vanaja SK, Rathinam VA, Aune MH, et al. The NLRP12 inflammasome recognizes Yersinia pestis. Immunity (2012) 37(1):96-107. doi:10.1016/j.immuni.2012.07.006
-
(2012)
Immunity
, vol.37
, Issue.1
, pp. 96-107
-
-
Vladimer, G.I.1
Weng, D.2
Paquette, S.W.3
Vanaja, S.K.4
Rathinam, V.A.5
Aune, M.H.6
-
86
-
-
33745298519
-
Nuclear factor-kappaB in cancer development and progression
-
doi:10.1038/nature04870
-
Karin M. Nuclear factor-kappaB in cancer development and progression. Nature (2006) 441(7092):431-6. doi:10.1038/nature04870
-
(2006)
Nature
, vol.441
, Issue.7092
, pp. 431-436
-
-
Karin, M.1
-
87
-
-
84858643750
-
Inflammasomes in carcinogenesis and anticancer immune responses
-
doi:10.1038/ni.2224
-
Zitvogel L, Kepp O, Galluzzi L, Kroemer G. Inflammasomes in carcinogenesis and anticancer immune responses. Nat Immunol (2012) 13(4):343-51. doi:10.1038/ni.2224
-
(2012)
Nat Immunol
, vol.13
, Issue.4
, pp. 343-351
-
-
Zitvogel, L.1
Kepp, O.2
Galluzzi, L.3
Kroemer, G.4
-
88
-
-
0037418208
-
IL-1 is required for tumor invasiveness and angiogenesis
-
doi:10.1073/pnas.0437939100
-
Voronov E, Shouval DS, Krelin Y, Cagnano E, Benharroch D, Iwakura Y, et al. IL-1 is required for tumor invasiveness and angiogenesis. Proc Natl Acad Sci U S A (2003) 100(5):2645-50. doi:10.1073/pnas.0437939100
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, Issue.5
, pp. 2645-2650
-
-
Voronov, E.1
Shouval, D.S.2
Krelin, Y.3
Cagnano, E.4
Benharroch, D.5
Iwakura, Y.6
-
89
-
-
33847060965
-
Interleukin-1beta-driven inflammation promotes the development and invasiveness of chemical carcinogen-induced tumors
-
doi:10.1158/0008-5472.CAN-06-2956
-
Krelin Y, Voronov E, Dotan S, Elkabets M, Reich E, Fogel M, et al. Interleukin-1beta-driven inflammation promotes the development and invasiveness of chemical carcinogen-induced tumors. Cancer Res (2007) 67(3):1062-71. doi:10.1158/0008-5472.CAN-06-2956
-
(2007)
Cancer Res
, vol.67
, Issue.3
, pp. 1062-1071
-
-
Krelin, Y.1
Voronov, E.2
Dotan, S.3
Elkabets, M.4
Reich, E.5
Fogel, M.6
-
90
-
-
0036644713
-
Proinflammatory cytokine IL-1 beta promotes tumor growth of Lewis lung carcinoma by induction of angiogenic factors: in vivo analysis of tumor-stromal interaction
-
Saijo Y, Tanaka M, Miki M, Usui K, Suzuki T, Maemondo M, et al. Proinflammatory cytokine IL-1 beta promotes tumor growth of Lewis lung carcinoma by induction of angiogenic factors: in vivo analysis of tumor-stromal interaction. J Immunol (2002) 169(1):469-75.
-
(2002)
J Immunol
, vol.169
, Issue.1
, pp. 469-475
-
-
Saijo, Y.1
Tanaka, M.2
Miki, M.3
Usui, K.4
Suzuki, T.5
Maemondo, M.6
-
91
-
-
77954551165
-
Why not treat human cancer with interleukin-1 blockade?
-
doi:10.1007/s10555-010-9229-0
-
Dinarello CA. Why not treat human cancer with interleukin-1 blockade? Cancer Metastasis Rev (2010) 29(2):317-29. doi:10.1007/s10555-010-9229-0
-
(2010)
Cancer Metastasis Rev
, vol.29
, Issue.2
, pp. 317-329
-
-
Dinarello, C.A.1
-
92
-
-
33845212729
-
Interleukin-1 and cancer progression: the emerging role of interleukin-1 receptor antagonist as a novel therapeutic agent in cancer treatment
-
doi:10.1186/1479-5876-4-48
-
Lewis AM, Varghese S, Xu H, Alexander HR. Interleukin-1 and cancer progression: the emerging role of interleukin-1 receptor antagonist as a novel therapeutic agent in cancer treatment. J Transl Med (2006) 4:48. doi:10.1186/1479-5876-4-48
-
(2006)
J Transl Med
, vol.4
, pp. 48
-
-
Lewis, A.M.1
Varghese, S.2
Xu, H.3
Alexander, H.R.4
-
93
-
-
61449122079
-
Induction of a chronic disease state in patients with smoldering or indolent multiple myeloma by targeting interleukin 1{beta}-induced interleukin 6 production and the myeloma proliferative component
-
doi:10.4065/84.2.114
-
Lust JA, Lacy MQ, Zeldenrust SR, Dispenzieri A, Gertz MA, Witzig TE, et al. Induction of a chronic disease state in patients with smoldering or indolent multiple myeloma by targeting interleukin 1{beta}-induced interleukin 6 production and the myeloma proliferative component. Mayo Clin Proc (2009) 84(2):114-22. doi:10.4065/84.2.114
-
(2009)
Mayo Clin Proc
, vol.84
, Issue.2
, pp. 114-122
-
-
Lust, J.A.1
Lacy, M.Q.2
Zeldenrust, S.R.3
Dispenzieri, A.4
Gertz, M.A.5
Witzig, T.E.6
-
94
-
-
80051698136
-
IL-18 induces PD-1-dependent immunosuppression in cancer
-
doi:10.1158/0008-5472.CAN-11-0993
-
Terme M, Ullrich E, Aymeric L, Meinhardt K, Desbois M, Delahaye N, et al. IL-18 induces PD-1-dependent immunosuppression in cancer. Cancer Res (2011) 71(16):5393-9. doi:10.1158/0008-5472.CAN-11-0993
-
(2011)
Cancer Res
, vol.71
, Issue.16
, pp. 5393-5399
-
-
Terme, M.1
Ullrich, E.2
Aymeric, L.3
Meinhardt, K.4
Desbois, M.5
Delahaye, N.6
-
95
-
-
0037439704
-
Interleukin-18 binding protein reduces B16 melanoma hepatic metastasis by neutralizing adhesiveness and growth factors of sinusoidal endothelium
-
Carrascal MT, Mendoza L, Valcarcel M, Salado C, Egilegor E, Telleria N, et al. Interleukin-18 binding protein reduces B16 melanoma hepatic metastasis by neutralizing adhesiveness and growth factors of sinusoidal endothelium. Cancer Res (2003) 63(2):491-7.
-
(2003)
Cancer Res
, vol.63
, Issue.2
, pp. 491-497
-
-
Carrascal, M.T.1
Mendoza, L.2
Valcarcel, M.3
Salado, C.4
Egilegor, E.5
Telleria, N.6
-
96
-
-
12944254582
-
IL-18 regulates IL-1beta-dependent hepatic melanoma metastasis via vascular cell adhesion molecule-1
-
doi:10.1073/pnas.97.2.734
-
Vidal-Vanaclocha F, Fantuzzi G, Mendoza L, Fuentes AM, Anasagasti MJ, Martin J, et al. IL-18 regulates IL-1beta-dependent hepatic melanoma metastasis via vascular cell adhesion molecule-1. Proc Natl Acad Sci U S A (2000) 97(2):734-9. doi:10.1073/pnas.97.2.734
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, Issue.2
, pp. 734-739
-
-
Vidal-Vanaclocha, F.1
Fantuzzi, G.2
Mendoza, L.3
Fuentes, A.M.4
Anasagasti, M.J.5
Martin, J.6
-
97
-
-
0042062486
-
Prognostic value of serum IL-18 and nitric oxide activity in breast cancer patients at operable stage
-
doi:10.1097/01.COC.0000027416.15170.53
-
Gunel N, Coskun U, Sancak B, Hasdemir O, Sare M, Bayram O, et al. Prognostic value of serum IL-18 and nitric oxide activity in breast cancer patients at operable stage. Am J Clin Oncol (2003) 26(4):416-21. doi:10.1097/01.COC.0000027416.15170.53
-
(2003)
Am J Clin Oncol
, vol.26
, Issue.4
, pp. 416-421
-
-
Gunel, N.1
Coskun, U.2
Sancak, B.3
Hasdemir, O.4
Sare, M.5
Bayram, O.6
-
98
-
-
2542572613
-
Constitutive expression of interleukin-18 in head and neck squamous carcinoma cells
-
doi:10.1002/hed.20011
-
Martone T, Bellone G, Pagano M, Beatrice F, Palonta F, Emanuelli G, et al. Constitutive expression of interleukin-18 in head and neck squamous carcinoma cells. Head Neck (2004) 26(6):494-503. doi:10.1002/hed.20011
-
(2004)
Head Neck
, vol.26
, Issue.6
, pp. 494-503
-
-
Martone, T.1
Bellone, G.2
Pagano, M.3
Beatrice, F.4
Palonta, F.5
Emanuelli, G.6
-
99
-
-
0034873384
-
Serum levels of interleukin-18 and sICAM-1 in patients affected by breast cancer: preliminary considerations
-
Merendino RA, Gangemi S, Ruello A, Bene A, Losi E, Lonbardo G, et al. Serum levels of interleukin-18 and sICAM-1 in patients affected by breast cancer: preliminary considerations. Int J Biol Markers (2001) 16(2):126-9.
-
(2001)
Int J Biol Markers
, vol.16
, Issue.2
, pp. 126-129
-
-
Merendino, R.A.1
Gangemi, S.2
Ruello, A.3
Bene, A.4
Losi, E.5
Lonbardo, G.6
-
100
-
-
79959690793
-
Interleukin (IL)-18, a biomarker of human ovarian carcinoma, is predominantly released as biologically inactive precursor
-
doi:10.1002/ijc.25757
-
Orengo AM, Fabbi M, Miglietta L, Andreani C, Bruzzone M, Puppo A, et al. Interleukin (IL)-18, a biomarker of human ovarian carcinoma, is predominantly released as biologically inactive precursor. Int J Cancer (2011) 129(5):1116-25. doi:10.1002/ijc.25757
-
(2011)
Int J Cancer
, vol.129
, Issue.5
, pp. 1116-1125
-
-
Orengo, A.M.1
Fabbi, M.2
Miglietta, L.3
Andreani, C.4
Bruzzone, M.5
Puppo, A.6
-
101
-
-
0001543990
-
Interleukin-18 and the costimulatory molecule B7-1 have a synergistic anti-tumor effect on murine melanoma; implication of combined immunotherapy for poorly immunogenic malignancy
-
doi:10.1038/sj.jid.5600685
-
Cho D, Kim TG, Lee W, Hwang YI, Cho HI, Han H, et al. Interleukin-18 and the costimulatory molecule B7-1 have a synergistic anti-tumor effect on murine melanoma; implication of combined immunotherapy for poorly immunogenic malignancy. J Invest Dermatol (2000) 114(5):928-34. doi:10.1038/sj.jid.5600685
-
(2000)
J Invest Dermatol
, vol.114
, Issue.5
, pp. 928-934
-
-
Cho, D.1
Kim, T.G.2
Lee, W.3
Hwang, Y.I.4
Cho, H.I.5
Han, H.6
|