Small-molecule SMAC mimetics as new cancer therapeutics

Pharmacology and Therapeutics

Volumn 144, Issue 1, 2014, Pages 82-95

  Bai, Longchuan ^a   Smith, David C ^a   Wang, Shaomeng ^a,b  

^a UNIVERSITY OF MICHIGAN COMPREHENSIVE CANCER CENTER   (United States)

^b Division of Hematology Oncology 3216 Cancer Center   (United States)

Author keywords

Apoptosis; Inhibitors; SMAC mimetics

Indexed keywords

ADIPOCYTOKINE; ATRIAL NATRIURETIC FACTOR DERIVATIVE; CYCLIC GMP; GLUCOSE; INSULIN; NATRIURETIC FACTOR; PEPTIDE HORMONE; ANTINEOPLASTIC AGENT; BIRC2 PROTEIN, HUMAN; BIRC3 PROTEIN, HUMAN; DIABLO PROTEIN, HUMAN; INHIBITOR OF APOPTOSIS PROTEIN; MITOCHONDRIAL PROTEIN; SIGNAL PEPTIDE; X LINKED INHIBITOR OF APOPTOSIS; XIAP PROTEIN, HUMAN;

ADIPOSE TISSUE; ARTERIAL PRESSURE; BROWN ADIPOSE TISSUE; CONGESTIVE HEART FAILURE; EXERCISE; HORMONE RELEASE; HUMAN; HYPERTENSION; INSULIN RESISTANCE; LIPID OXIDATION; LIPOLYSIS; METABOLIC SYNDROME X; MITOCHONDRIAL RESPIRATION; MUSCLE METABOLISM; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; OBESITY; PANDEMIC; PATHOPHYSIOLOGY; PRIORITY JOURNAL; REVIEW; SATIETY; SIGNAL TRANSDUCTION; SODIUM ABSORPTION; WHITE ADIPOSE TISSUE; ANIMAL; APOPTOSIS; CELL SURVIVAL; DRUG DESIGN; DRUG EFFECTS; METABOLISM; NEOPLASMS; PATHOLOGY; PHYSIOLOGY;

ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL SURVIVAL; DRUG DESIGN; HUMANS; INHIBITOR OF APOPTOSIS PROTEINS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MITOCHONDRIAL PROTEINS; NEOPLASMS; X-LINKED INHIBITOR OF APOPTOSIS PROTEIN;

EID: 84906938621     PISSN: 01637258     EISSN: 1879016X     Source Type: Journal    
DOI: 10.1016/j.pharmthera.2014.05.007     Document Type: Review

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