-
1
-
-
77950353786
-
Homeostasis and inflammation in the intestine
-
Garrett, W. S., Gordon, J. I. & Glimcher, L. H. Homeostasis and inflammation in the intestine. Cell 140, 859-870 (2010).
-
(2010)
Cell
, vol.140
, pp. 859-870
-
-
Garrett, W.S.1
Gordon, J.I.2
Glimcher, L.H.3
-
2
-
-
77950343791
-
Pattern recognition receptors and inflammation
-
Takeuchi, O. & Akira, S. Pattern recognition receptors and inflammation. Cell 140, 805-820 (2010).
-
(2010)
Cell
, vol.140
, pp. 805-820
-
-
Takeuchi, O.1
Akira, S.2
-
3
-
-
44349124113
-
The genetics and immunopathogenesis of inflammatory bowel disease
-
DOI 10.1038/nri2340, PII NRI2340
-
Cho, J. H. The genetics and immunopathogenesis of inflammatory bowel disease. Nature Rev. Immunol. 8, 458-466 (2008). (Pubitemid 351733422)
-
(2008)
Nature Reviews Immunology
, vol.8
, Issue.6
, pp. 458-466
-
-
Cho, J.H.1
-
4
-
-
70350509805
-
Intestinal mucosal barrier function in health and disease
-
Turner, J. R. Intestinal mucosal barrier function in health and disease. Nature Rev. Immunol. 9, 799-809 (2009).
-
(2009)
Nature Rev. Immunol.
, vol.9
, pp. 799-809
-
-
Turner, J.R.1
-
5
-
-
0038615855
-
Nod1 detects a unique muropeptide from gram-negative bacterial peptidoglycan
-
DOI 10.1126/science.1084677
-
Girardin, S. E. et al. Nod1 detects a unique muropeptide from Gram-negative bacterial peptidoglycan. Science 300, 1584-1587 (2003). (Pubitemid 36682892)
-
(2003)
Science
, vol.300
, Issue.5625
, pp. 1584-1587
-
-
Girardin, S.E.1
Boneca, I.G.2
Carneiro, L.A.M.3
Antignac, A.4
Jehanno, M.5
Viala, J.6
Tedin, K.7
Taha, M.-K.8
Labigne, A.9
Zahringer, U.10
Coyle, A.J.11
DiStefano, P.S.12
Bertin, J.13
Sansonetti, P.J.14
Philpott, D.J.15
-
6
-
-
1342344961
-
Nod1 is an essential signal transducer in intestinal epithelial cells infected with bacteria that avoid recognition by toll-like receptors
-
DOI 10.1128/IAI.72.3.1487-1495.2004
-
Kim, J. G., Lee, S. J. & Kagnoff, M. F. Nod1 is an essential signal transducer in intestinal epithelial cells infected with bacteria that avoid recognition by toll-like receptors. Infect. Immun. 72, 1487-1495 (2004). (Pubitemid 38263771)
-
(2004)
Infection and Immunity
, vol.72
, Issue.3
, pp. 1487-1495
-
-
Kim, J.G.1
Lee, S.J.2
Kagnoff, M.F.3
-
7
-
-
31944437924
-
Nod1 acts as an intracellular receptor to stimulate chemokine production and neutrophil recruitment in vivo
-
Masumoto, J. et al. Nod1 acts as an intracellular receptor to stimulate chemokine production and neutrophil recruitment in vivo. J. Exp. Med. 203, 203-213 (2006).
-
(2006)
J. Exp. Med.
, vol.203
, pp. 203-213
-
-
Masumoto, J.1
-
8
-
-
2942535858
-
Reciprocal cross-talk between Nod2 and TAK1 signaling pathways
-
DOI 10.1074/jbc.M400682200
-
Chen, C. M., Gong, Y., Zhang, M. & Chen, J. J. Reciprocal cross-talk between Nod2 and TAK1 signaling pathways. J. Biol. Chem. 279, 25876-25882 (2004). (Pubitemid 38756853)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.24
, pp. 25876-25882
-
-
Chen, C.-M.1
Gong, Y.2
Zhang, M.3
Chen, J.-J.4
-
9
-
-
13244292161
-
Nod2-dependent regulation of innate and adaptive immunity in the intestinal tract
-
DOI 10.1126/science.1104911
-
Kobayashi, K. S. et al.Nod2-dependent regulationof innateandadaptiveimmunity in the intestinal tract. Science 307, 731-734 (2005). (Pubitemid 40194644)
-
(2005)
Science
, vol.307
, Issue.5710
, pp. 731-734
-
-
Kobayashi, K.S.1
Chamaillard, M.2
Ogura, Y.3
Henegariu, O.4
Inohara, N.5
Nunez, G.6
Flavell, R.A.7
-
10
-
-
0033532091
-
Human CARD4 protein is a novel CED-4/Apaf-1 cell death family member that activates NF-kB
-
Bertin, J. et al. Human CARD4 protein is a novel CED-4/Apaf-1 cell death family member that activates NF-kB. J. Biol. Chem. 274, 12955-12958 (1999).
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 12955-12958
-
-
Bertin, J.1
-
11
-
-
0033591330
-
Nod1, an Apaf-1-like activator of caspase-9 and nuclear factor-kB
-
Inohara, N. et al.Nod1, an Apaf-1-like activator of caspase-9 and nuclear factor-kB. J. Biol. Chem. 274, 14560-14567 (1999).
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 14560-14567
-
-
Inohara, N.1
-
12
-
-
33847376042
-
Reconstituted NALP1 inflammasome reveals two-step mechanism of caspase-1 activation
-
DOI 10.1016/j.molcel.2007.01.032, PII S1097276507000780
-
Faustin, B. et al. Reconstituted NALP1 inflammasome reveals two-step mechanism of caspase-1 activation. Mol. Cell 25, 713-724 (2007). (Pubitemid 46341921)
-
(2007)
Molecular Cell
, vol.25
, Issue.5
, pp. 713-724
-
-
Faustin, B.1
Lartigue, L.2
Bruey, J.-M.3
Luciano, F.4
Sergienko, E.5
Bailly-Maitre, B.6
Volkmann, N.7
Hanein, D.8
Rouiller, I.9
Reed, J.C.10
-
13
-
-
33947717153
-
Bcl-2 and Bcl-XL regulate proinflammatory caspase-1 activation by interaction with NALP1
-
Bruey, J. M. et al. Bcl-2 and Bcl-XL regulate proinflammatory caspase-1 activation by interaction with NALP1. Cell 129, 45-56 (2007).
-
(2007)
Cell
, vol.129
, pp. 45-56
-
-
Bruey, J.M.1
-
14
-
-
0032524885
-
The C. elegans Protein EGL-1 is required for programmed cell death and interacts with the Bcl-2-like protein CED-9
-
DOI 10.1016/S0092-8674(00)81182-4
-
Conradt, B. & Horvitz, H. R. The C. elegans protein EGL-1 is required for programmed cell death and interacts with the Bcl-2-like protein CED-9. Cell 93, 519-529 (1998). (Pubitemid 28240714)
-
(1998)
Cell
, vol.93
, Issue.4
, pp. 519-529
-
-
Conradt, B.1
Horvitz, H.R.2
-
15
-
-
14944348965
-
The role of BH3-only proteins in the immune system
-
DOI 10.1038/nri1568
-
Strasser, A. The role of BH3-only proteins in the immune system. Nature Rev. Immunol. 5, 189-200 (2005). (Pubitemid 40364821)
-
(2005)
Nature Reviews Immunology
, vol.5
, Issue.3
, pp. 189-200
-
-
Strasser, A.1
-
16
-
-
0034799401
-
Phosphorylation of Bid by casein kinases I and II regulates its cleavage by caspase 8
-
DOI 10.1016/S1097-2765(01)00335-5
-
Desagher, S. et al. Phosphorylation of bid by casein kinases I and II regulates its cleavage by caspase 8. Mol. Cell 8, 601-611 (2001). (Pubitemid 32946937)
-
(2001)
Molecular Cell
, vol.8
, Issue.3
, pp. 601-611
-
-
Desagher, S.1
Osen-Sand, A.2
Montessuit, S.3
Magnenat, E.4
Vilbois, F.5
Hochmann, A.6
Journot, L.7
Antonsson, B.8
Martinou, J.-C.9
-
17
-
-
34547176642
-
Unravelling the pathogenesis of inflammatory bowel disease
-
DOI 10.1038/nature06005, PII NATURE06005
-
Xavier, R. J. & Podolsky, D. K. Unravelling the pathogenesis of inflammatory bowel disease. Nature 448, 427-434 (2007). (Pubitemid 47123518)
-
(2007)
Nature
, vol.448
, Issue.7152
, pp. 427-434
-
-
Xavier, R.J.1
Podolsky, D.K.2
-
18
-
-
77950390163
-
Bidmediates anti-apoptotic COX-2 induction through the IKKb/NFkB pathway due to 5-MCDE exposure
-
Luo, W. et al. Bidmediates anti-apoptotic COX-2 induction through the IKKb/NFkB pathway due to 5-MCDE exposure. Curr. Cancer Drug Targets 10, 96-106 (2010).
-
(2010)
Curr. Cancer Drug Targets
, vol.10
, pp. 96-106
-
-
Luo, W.1
-
19
-
-
0029807585
-
BID: A novel BH3 domain-only death agonist
-
Wang, K., Yin, X. M., Chao, D. T., Milliman, C. L. & Korsmeyer, S. J. BID: a novel BH3 domain-only death agonist. Genes Dev. 10, 2859-2869 (1996). (Pubitemid 26394246)
-
(1996)
Genes and Development
, vol.10
, Issue.22
, pp. 2859-2869
-
-
Wang, K.1
Yin, X.-M.2
Chao, D.T.3
Milliman, C.L.4
Korsmeyer, S.J.5
-
20
-
-
62649092113
-
Mechanism of Bcl-2 and Bcl-X(L) inhibition of NLRP1 inflammasome: Loop domain-dependent suppression of ATP binding and oligomerization
-
Faustin, B. et al. Mechanism of Bcl-2 and Bcl-X(L) inhibition of NLRP1 inflammasome: loop domain-dependent suppression of ATP binding and oligomerization. Proc. Natl Acad. Sci. USA 106, 3935-3940 (2009).
-
(2009)
Proc. Natl Acad. Sci. USA
, vol.106
, pp. 3935-3940
-
-
Faustin, B.1
-
21
-
-
1442310957
-
Structural biology of the Bcl-2 family of proteins
-
DOI 10.1016/j.bbamcr.2003.08.012, PII S0167488903001757
-
Petros, A. M., Olejniczak, E. T. & Fesik, S. W. Structural biology of the Bcl-2 family of proteins. Biochim. Biophys. Acta 1644, 83-94 (2004). (Pubitemid 38281265)
-
(2004)
Biochimica et Biophysica Acta - Molecular Cell Research
, vol.1644
, Issue.2-3
, pp. 83-94
-
-
Petros, A.M.1
Olejniczak, E.T.2
Fesik, S.W.3
-
22
-
-
38549084725
-
A critical role of RICK/RIP2 polyubiquitination in Nod-induced NF-kB activation
-
Hasegawa, M. et al. A critical role of RICK/RIP2 polyubiquitination in Nod-induced NF-kB activation. EMBO J. 27, 373-383 (2007).
-
(2007)
EMBO J.
, vol.27
, pp. 373-383
-
-
Hasegawa, M.1
-
23
-
-
11144289688
-
The Crohn's disease protein, NOD2, requires RIP2 in order to induce ubiquitinylation of a novel site on NEMO
-
DOI 10.1016/j.cub.2004.12.032, PII S0960982204009881
-
Abbott, D. W., Wilkins, A., Asara, J. M. & Cantley, L. C. The Crohn's disease protein, NOD2, requires RIP2 in order to induce ubiquitinylation of a novel site on NEMO. Curr. Biol. 14, 2217-2227 (2004). (Pubitemid 40033358)
-
(2004)
Current Biology
, vol.14
, Issue.24
, pp. 2217-2227
-
-
Abbott, D.W.1
Wilkins, A.2
Asara, J.M.3
Cantley, L.C.4
-
24
-
-
33845768987
-
Integrating cell-signalling pathways with NF-κB and IKK function
-
DOI 10.1038/nrm2083, PII NRM2083
-
Perkins, N. D. Integrating cell-signalling pathways with NF-kB and IKK function. Nature Rev. Mol. Cell Biol. 8, 49-62 (2007). (Pubitemid 46012014)
-
(2007)
Nature Reviews Molecular Cell Biology
, vol.8
, Issue.1
, pp. 49-62
-
-
Perkins, N.D.1
-
25
-
-
33846469538
-
The adaptor protein CARD9 is required for innate immune responses to intracellular pathogens
-
Hsu, Y. M. et al. The adaptor protein CARD9 is required for innate immune responses to intracellular pathogens. Nature Immunol. 8, 198-205 (2007).
-
(2007)
Nature Immunol.
, vol.8
, pp. 198-205
-
-
Hsu, Y.M.1
-
26
-
-
38849163741
-
Muramyl dipeptide activation of nucleotide-binding oligomerization domain 2 protects mice from experimental colitis
-
DOI 10.1172/JCI33145
-
Watanabe, T. et al. Muramyl dipeptide activation of nucleotide-binding oligomerization domain 2 protects mice from experimental colitis. J. Clin. Invest. 118, 545-559 (2008). (Pubitemid 351206545)
-
(2008)
Journal of Clinical Investigation
, vol.118
, Issue.2
, pp. 545-559
-
-
Watanabe, T.1
Asano, N.2
Murray, P.J.3
Ozato, K.4
Tailor, P.5
Fuss, I.J.6
Kitani, A.7
Strober, W.8
-
27
-
-
66949138341
-
Cellular inhibitors of apoptosis cIAP1 and cIAP2 are required for innate immunity signaling by the pattern recognition receptors NOD1 and NOD2
-
Bertrand, M. J. et al. Cellular inhibitors of apoptosis cIAP1 and cIAP2 are required for innate immunity signaling by the pattern recognition receptors NOD1 and NOD2. Immunity 30, 789-801 (2009).
-
(2009)
Immunity
, vol.30
, pp. 789-801
-
-
Bertrand, M.J.1
-
28
-
-
34547638394
-
Activation of toll-like receptor 3 protects against DSS-induced acute colitis
-
DOI 10.1002/ibd.20142
-
Vijay-Kumar, M. et al. Activation of toll-like receptor 3 protects against DSSinduced acute colitis. Inflamm. Bowel Dis. 13, 856-864 (2007). (Pubitemid 47203863)
-
(2007)
Inflammatory Bowel Diseases
, vol.13
, Issue.7
, pp. 856-864
-
-
Vijay-Kumar, M.1
Wu, H.2
Aitken, J.3
Kolachala, V.L.4
Neish, A.5
Sitaraman, S.V.6
Gewirtz, A.T.7
-
29
-
-
0035895992
-
Nod2, a Nod1/Apaf-1 family member that is restricted to monocytes and activates NF-kB
-
Ogura, Y. et al. Nod2, a Nod1/Apaf-1 family member that is restricted to monocytes and activates NF-kB. J. Biol. Chem. 276, 4812-4818 (2001).
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 4812-4818
-
-
Ogura, Y.1
-
31
-
-
0033003760
-
A simple statistical parameter for use in evaluation and validation of high throughput screening assays
-
DOI 10.1177/108705719900400206
-
Zhang, J. H.,Chung, T. D.& Oldenburg, K. R.Asimple statisticalparameter for use in evaluation and validationof high throughput screening assays. J. Biomol. Screen. 4, 67-73 (1999). (Pubitemid 29278954)
-
(1999)
Journal of Biomolecular Screening
, vol.4
, Issue.2
, pp. 67-73
-
-
Zhang, J.-H.1
Chung, T.D.Y.2
Oldenburg, K.R.3
-
32
-
-
13444312083
-
The PANTHER database of protein families, subfamilies, functions and pathways
-
DOI 10.1093/nar/gki078
-
Mi, H. et al. The PANTHER database of protein families, subfamilies, functions and pathways. Nucleic Acids Res. 33, D284-D288 (2005). (Pubitemid 40207879)
-
(2005)
Nucleic Acids Research
, vol.33
, Issue.DATABASE ISSUE
-
-
Mi, H.1
Lazareva-Ulitsky, B.2
Loo, R.3
Kejariwal, A.4
Vandergriff, J.5
Rabkin, S.6
Guo, N.7
Muruganujan, A.8
Doremieux, O.9
Campbell, M.J.10
Kitano, H.11
Thomas, P.D.12
-
33
-
-
33847264343
-
Enrichment or depletion of a GO category within a class of genes: Which test?
-
DOI 10.1093/bioinformatics/btl633
-
Rivals, I. et al. Enrichment or depletion of a GO category within a class of genes: which test? Bioinformatics 23, 401-407 (2007). (Pubitemid 46323119)
-
(2007)
Bioinformatics
, vol.23
, Issue.4
, pp. 401-407
-
-
Rivals, I.1
Personnaz, L.2
Taing, L.3
Potier, M.-C.4
-
35
-
-
9444225935
-
Java Treeview - Extensible visualization of microarray data
-
DOI 10.1093/bioinformatics/bth349
-
Saldanha, A. J. Java Treeview-extensible visualization of microarray data. Bioinformatics 20, 3246-3248 (2004). (Pubitemid 39619217)
-
(2004)
Bioinformatics
, vol.20
, Issue.17
, pp. 3246-3248
-
-
Saldanha, A.J.1
-
36
-
-
18144399957
-
Humanin binds and nullifies bid activity by blocking its activation of Bax and Bak
-
DOI 10.1074/jbc.M411902200
-
Zhai, D. et al. Humanin binds and nullifies Bid activity by blocking its activation of Bax and Bak. J. Biol. Chem. 280, 15815-15824 (2005). (Pubitemid 40616702)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.16
, pp. 15815-15824
-
-
Zhai, D.1
Luciano, F.2
Zhu, X.3
Guo, B.4
Satterthwait, A.C.5
Reed, J.C.6
|