-
1
-
-
77950221314
-
Mechanism of neurodegeneration of neurons with mitochondrial DNA mutations
-
Abramov AY, Smulders-Srinivasan TK, Kirby DM, Acin-Perez R, Enriquez JA, Lightowlers RN, Duchen MR, and Turnbull DM. Mechanism of neurodegeneration of neurons with mitochondrial DNA mutations. Brain 133: 797-807, 2010.
-
(2010)
Brain
, vol.133
, pp. 797-807
-
-
Abramov, A.Y.1
Smulders-Srinivasan, T.K.2
Kirby, D.M.3
Acin-Perez, R.4
Enriquez, J.A.5
Lightowlers, R.N.6
Duchen, M.R.7
Turnbull, D.M.8
-
2
-
-
77956223101
-
Calcium and mitochondrial reactive oxygen species generation: How to read the facts
-
Adam-Vizi V and Starkov AA. Calcium and mitochondrial reactive oxygen species generation: how to read the facts. J Alzheimers Dis 20 Suppl: S413-S426, 2010.
-
(2010)
J Alzheimers Dis 20 Suppl
-
-
Adam-Vizi, V.1
Starkov, A.A.2
-
3
-
-
35048841732
-
Targeting cell signaling pathways for drug discovery: An old lock needs a new key
-
Aggarwal BB, Sethi G, Baladandayuthapani V, Krishnan S, and Shishodia S. Targeting cell signaling pathways for drug discovery: an old lock needs a new key. J Cell Biochem 102: 580-592, 2007.
-
(2007)
J Cell Biochem
, vol.102
, pp. 580-592
-
-
Aggarwal, B.B.1
Sethi, G.2
Baladandayuthapani, V.3
Krishnan, S.4
Shishodia, S.5
-
4
-
-
75149192820
-
Sirtuins as novel targets for Alzheimer's disease and other neurodegenerative disorders: Experimental and genetic evidence
-
Albani D, Polito L, and Forloni G. Sirtuins as novel targets for Alzheimer's disease and other neurodegenerative disorders: experimental and genetic evidence. J Alzheimers Dis 19: 11-26, 2010.
-
(2010)
J Alzheimers Dis
, vol.19
, pp. 11-26
-
-
Albani, D.1
Polito, L.2
Forloni, G.3
-
5
-
-
0037453223
-
Ruthenium red, inhibitor of mitochondrial Ca2 + uniporter, inhibits curcumininduced apoptosis via the prevention of intracellular Ca2 + depletion and cytochrome c release
-
Bae JH, Park JW, and Kwon TK. Ruthenium red, inhibitor of mitochondrial Ca2 + uniporter, inhibits curcumininduced apoptosis via the prevention of intracellular Ca2 + depletion and cytochrome c release. Biochem Biophys Res Commun 303: 1073-1079, 2003.
-
(2003)
Biochem Biophys Res Commun
, vol.303
, pp. 1073-1079
-
-
Bae, J.H.1
Park, J.W.2
Kwon, T.K.3
-
6
-
-
77949913600
-
Uncoupling protein-2 and cancer
-
Baffy G. Uncoupling protein-2 and cancer. Mitochondrion 10: 243-252, 2010.
-
(2010)
Mitochondrion
, vol.10
, pp. 243-252
-
-
Baffy, G.1
-
7
-
-
84864508209
-
Antidiabetic antihyperlipidemic and antioxidant effects of the flavonoid rich fraction of Pilea microphylla (L.) in high fat diet/ streptozoticin-induced diabetes in mice
-
[Epub ahead of print]; DOI 10.1016/j.etp.2010.12.009
-
Bansal P, Paul P, Mudgal J, G Nayak P, Thomas Pannakal S, Priyadarsini KI, and Unnikrishnan MK. Antidiabetic, antihyperlipidemic and antioxidant effects of the flavonoid rich fraction of Pilea microphylla (L.) in high fat diet/ streptozoticin-induced diabetes in mice. Exp Toxicol Pathol 2011, [Epub ahead of print]; DOI 10.1016/j.etp.2010.12.009
-
(2011)
Exp Toxicol Pathol
-
-
Bansal, P.1
Paul, P.2
Mudgal, J.3
Nayak, P.G.4
Thomas Pannakal, S.5
Priyadarsini, K.I.6
Unnikrishnan, M.K.7
-
8
-
-
63049135666
-
An in vitro screening cascade to identify neuroprotective antioxidants in ALS
-
Barber SC, Higginbottom A, Mead RJ, Barber S, and Shaw PJ. An in vitro screening cascade to identify neuroprotective antioxidants in ALS. Free Radic Biol Med 46: 1127-1138, 2009.
-
(2009)
Free Radic Biol Med
, vol.46
, pp. 1127-1138
-
-
Barber, S.C.1
Higginbottom, A.2
Mead, R.J.3
Barber, S.4
Shaw, P.J.5
-
9
-
-
33751072349
-
Resveratrol improves health and survival of mice on a high-calorie diet
-
Baur JA, Pearson KJ, Price NL, Jamieson HA, Lerin C, Kalra A, Prabhu VV, Allard JS, Lopez-Lluch G, Lewis K, Pistell PJ, Poosala S, Becker KG, Boss O, Gwinn D, Wang M, Ramaswamy S, Fishbein KW, Spencer RG, Lakatta EG, Le Couteur D, Shaw RJ, Navas P, Puigserver P, Ingram DK, de Cabo R, and Sinclair DA. Resveratrol improves health and survival of mice on a high-calorie diet. Nature 444: 337-342, 2006.
-
(2006)
Nature
, vol.444
, pp. 337-342
-
-
Baur, J.A.1
Pearson, K.J.2
Price, N.L.3
Jamieson, H.A.4
Lerin, C.5
Kalra, A.6
Prabhu, V.V.7
Allard, J.S.8
Lopez-Lluch, G.9
Lewis, K.10
Pistell, P.J.11
Poosala, S.12
Becker, K.G.13
Boss, O.14
Gwinn, D.15
Wang, M.16
Ramaswamy, S.17
Fishbein, K.W.18
Spencer, R.G.19
Lakatta, E.G.20
Le Couteur, D.21
Shaw, R.J.22
Navas, P.23
Puigserver, P.24
Ingram, D.K.25
De Cabo, R.26
Sinclair, D.A.27
more..
-
10
-
-
77953812057
-
Multi-site control and regulation of mitochondrial energy production
-
Benard G, Bellance N, Jose C, Melser S, Nouette-Gaulain K, and Rossignol R. Multi-site control and regulation of mitochondrial energy production. Biochim Biophys Acta 1797: 698-709, 2010.
-
(2010)
Biochim Biophys Acta
, vol.1797
, pp. 698-709
-
-
Benard, G.1
Bellance, N.2
Jose, C.3
Melser, S.4
Nouette-Gaulain, K.5
Rossignol, R.6
-
11
-
-
0032827410
-
Mitochondrial transport of cations: Channels exchangers, and permeability transition
-
Bernardi P. Mitochondrial transport of cations: channels, exchangers, and permeability transition, Physiol Rev 79: 1127-1155, 1999.
-
(1999)
Physiol Rev
, vol.79
, pp. 1127-1155
-
-
Bernardi, P.1
-
12
-
-
57649155915
-
Dysfunction of mitochondria and sarcoplasmic reticulum in the pathogenesis of collagen VI muscular dystrophies
-
Bernardi P and Bonaldo P. Dysfunction of mitochondria and sarcoplasmic reticulum in the pathogenesis of collagen VI muscular dystrophies. Ann NY Acad Sci 1147: 303-311, 2008.
-
(2008)
Ann NY Acad Sci
, vol.1147
, pp. 303-311
-
-
Bernardi, P.1
Bonaldo, P.2
-
13
-
-
78149359547
-
Mitochondrially targeted anti-cancer agents
-
Biasutto L, Dong LF, Zoratti M, and Neuzil J. Mitochondrially targeted anti-cancer agents. Mitochondrion 10: 670-681, 2010.
-
(2010)
Mitochondrion
, vol.10
, pp. 670-681
-
-
Biasutto, L.1
Dong, L.F.2
Zoratti, M.3
Neuzil, J.4
-
14
-
-
71949109410
-
Soluble polyphenols: Synthesis and bioavailability of 3,4,5-tri(a-D-glucose-3-Osuccinyl) resveratrol
-
Biasutto L, Marotta E, Bradaschia A, Fallica M, Mattarei A, Garbisa S, Zoratti M, and Paradisi C. Soluble polyphenols: synthesis and bioavailability of 3,4,5-tri(a-D-glucose-3-Osuccinyl) resveratrol. Bioorg Med Chem Lett 19: 6721-6724, 2009.
-
(2009)
Bioorg Med Chem Lett
, vol.19
, pp. 6721-6724
-
-
Biasutto, L.1
Marotta, E.2
Bradaschia, A.3
Fallica, M.4
Mattarei, A.5
Garbisa, S.6
Zoratti, M.7
Paradisi, C.8
-
15
-
-
46449110295
-
Thiol chemistry in peroxidase catalysis and redox signaling
-
Bindoli A, Fukuto JM, and Forman HJ. Thiol chemistry in peroxidase catalysis and redox signaling. Antioxid Redox Signal 10: 1549-1564, 2008.
-
(2008)
Antioxid Redox Signal
, vol.10
, pp. 1549-1564
-
-
Bindoli, A.1
Fukuto, J.M.2
Forman, H.J.3
-
16
-
-
80052241805
-
Proapoptotic effects of longchain vitamin e metabolites in HepG2 cells are mediated by oxidative stress
-
Birringer M, Lington D, Vertuani S, Manfredini S, Scharlau D, Glei M, and Ristow M. Proapoptotic effects of longchain vitamin E metabolites in HepG2 cells are mediated by oxidative stress. Free Radic Biol Med 49: 1315-1322, 2010.
-
(2010)
Free Radic Biol Med
, vol.49
, pp. 1315-1322
-
-
Birringer, M.1
Lington, D.2
Vertuani, S.3
Manfredini, S.4
Scharlau, D.5
Glei, M.6
Ristow, M.7
-
17
-
-
43049176634
-
Health effects of quercetin: From antioxidant to nutraceutical
-
Boots AW, Haenen GR, and Bast A. Health effects of quercetin: from antioxidant to nutraceutical. Eur J Pharmacol 585: 325-337, 2008.
-
(2008)
Eur J Pharmacol
, vol.585
, pp. 325-337
-
-
Boots, A.W.1
Haenen, G.R.2
Bast, A.3
-
18
-
-
77956597409
-
Cardiac mitochondria and arrhythmias
-
Brown DA and O'Rourke B. Cardiac mitochondria and arrhythmias. Cardiovasc Res 88: 241-249, 2010.
-
(2010)
Cardiovasc Res
, vol.88
, pp. 241-249
-
-
Brown, D.A.1
O'Rourke, B.2
-
19
-
-
78649979775
-
Resveratrol commonly displays hormesis: Occurrence and biomedical significance
-
Calabrese EJ, Mattson MP, and Calabrese V. Resveratrol commonly displays hormesis: occurrence and biomedical significance. Hum Exp Toxicol 29: 980-1015, 2010.
-
(2010)
Hum Exp Toxicol
, vol.29
, pp. 980-1015
-
-
Calabrese, E.J.1
Mattson, M.P.2
Calabrese, V.3
-
20
-
-
77957349477
-
AMP-activated protein kinase and its downstream transcriptional pathways
-
Cantó C and Auwerx J. AMP-activated protein kinase and its downstream transcriptional pathways. Cell Mol Life Sci 67: 3407-3423, 2010.
-
(2010)
Cell Mol Life Sci
, vol.67
, pp. 3407-3423
-
-
Cantó, C.1
Auwerx, J.2
-
21
-
-
65349159205
-
Calcium homeostasis, selective vulnerability and Parkinson's disease
-
Chan CS, Gertler TS, and Surmeier DJ. Calcium homeostasis, selective vulnerability and Parkinson's disease. Trends Neurosci 32: 249-256, 2009.
-
(2009)
Trends Neurosci
, vol.32
, pp. 249-256
-
-
Chan, C.S.1
Gertler, T.S.2
Surmeier, D.J.3
-
22
-
-
77955298543
-
Dynamic regulation of mitochondrial fission through modification of the dynaminrelated protein Drp1
-
Chang CR and Blackstone C. Dynamic regulation of mitochondrial fission through modification of the dynaminrelated protein Drp1. Ann NY Acad Sci 1201: 34-39, 2010.
-
(2010)
Ann NY Acad Sci
, vol.1201
, pp. 34-39
-
-
Chang, C.R.1
Blackstone, C.2
-
23
-
-
79451471804
-
Combination of HPLC chromatogram and hypoglycemic effect identifies isoflavones as the principal active fraction of Belamcanda chinensis leaf extract in diabetes treatment
-
Chen Y, Wu CM, Dai RJ, Li L, Yu YH, Li Y, Meng WW, Zhang L, Zhang Y, and Deng YL. Combination of HPLC chromatogram and hypoglycemic effect identifies isoflavones as the principal active fraction of Belamcanda chinensis leaf extract in diabetes treatment. J Chromatogr B Analyt Technol Biomed Life Sci 879: 371-378, 2011.
-
(2011)
J Chromatogr B Analyt Technol Biomed Life Sci
, vol.879
, pp. 371-378
-
-
Chen, Y.1
Wu, C.M.2
Dai, R.J.3
Li, L.4
Yu, Y.H.5
Li, Y.6
Meng, W.W.7
Zhang, L.8
Zhang, Y.9
Deng, Y.L.10
-
24
-
-
77957358299
-
Mitochondrial dynamics in cell death and neurodegeneration
-
Cho DH, Nakamura T, and Lipton SA. Mitochondrial dynamics in cell death and neurodegeneration. Cell Mol Life Sci 67: 3435-3447, 2010.
-
(2010)
Cell Mol Life Sci
, vol.67
, pp. 3435-3447
-
-
Cho, D.H.1
Nakamura, T.2
Lipton, S.A.3
-
25
-
-
77649183809
-
AMPK-mediated GSK3beta inhibition by isoliquiritigenin contributes to protecting mitochondria against iron-catalyzed oxidative stress
-
Choi SH, Kim YW, and Kim SG. AMPK-mediated GSK3beta inhibition by isoliquiritigenin contributes to protecting mitochondria against iron-catalyzed oxidative stress. Biochem Pharmacol 79: 1352-1362, 2010.
-
(2010)
Biochem Pharmacol
, vol.79
, pp. 1352-1362
-
-
Choi, S.H.1
Kim, Y.W.2
Kim, S.G.3
-
26
-
-
77956176874
-
Regulation of SIRT1 in cellular functions: Role of polyphenols
-
Chung S, Yao H, Caito S, Hwang JW, Arunachalam G, and Rahman I. Regulation of SIRT1 in cellular functions: role of polyphenols. Arch Biochem Biophys 501: 79-90, 2010.
-
(2010)
Arch Biochem Biophys
, vol.501
, pp. 79-90
-
-
Chung, S.1
Yao, H.2
Caito, S.3
Hwang, J.W.4
Arunachalam, G.5
Rahman, I.6
-
27
-
-
76049083966
-
Reactive oxygen species, cellular redox systems, and apoptosis
-
Circu ML and Aw TY. Reactive oxygen species, cellular redox systems, and apoptosis. Free Radic Biol Med 48: 749-762, 2010.
-
(2010)
Free Radic Biol Med
, vol.48
, pp. 749-762
-
-
Circu, M.L.1
Aw, T.Y.2
-
28
-
-
55049120285
-
TMEM70 mutations cause isolated ATP synthase deficiency and neonatal mitochondrial encephalocardiomyopathy
-
Ćzková A, Stránecký V, Mayr JA, Tesarová M, Havĺcková V, Paul J, Ivánek R, Kuss AW, Hanśková H, Kaplanová V, Vrbacký M, Hartmannová H, Nosková L, Honźk T, Drahota Z, Magner M, Hejzlarová K, Sperl W, Zeman J, Houstek J, and Kmoch S. TMEM70 mutations cause isolated ATP synthase deficiency and neonatal mitochondrial encephalocardiomyopathy. Nat Genet 40: 1288-1290, 2008.
-
(2008)
Nat Genet
, vol.40
, pp. 1288-1290
-
-
Ćzková, A.1
Stránecký, V.2
Mayr, J.A.3
Tesarová, M.4
Havĺcková, V.5
Paul, J.6
Ivánek, R.7
Kuss, A.W.8
Hanśková, H.9
Kaplanová, V.10
Vrbacký, M.11
Hartmannová, H.12
Nosková, L.13
Honźk, T.14
Drahota, Z.15
Magner, M.16
Hejzlarová, K.17
Sperl, W.18
Zeman, J.19
Houstek, J.20
Kmoch, S.21
more..
-
30
-
-
73849144014
-
Mitochondrial peroxiredoxin involvement in antioxidant defence and redox signaling
-
Cox AG, Winterbourn CC, and Hampton MB. Mitochondrial peroxiredoxin involvement in antioxidant defence and redox signaling. Biochem J 425: 313-325, 2010.
-
(2010)
Biochem J
, vol.425
, pp. 313-325
-
-
Cox, A.G.1
Winterbourn, C.C.2
Hampton, M.B.3
-
31
-
-
78049434938
-
Agedependent cardiomyopathy in mitochondrial mutator mice is attenuated by overexpression of catalase targeted to mitochondria
-
Dai DF, Chen T, Wanagat J, Laflamme M, Marcinek DJ, Edmond MJ, Ngo CP, Prolla TA, and Rabinovitch PS. Agedependent cardiomyopathy in mitochondrial mutator mice is attenuated by overexpression of catalase targeted to mitochondria. Aging Cell 9: 536-544, 2010.
-
(2010)
Aging Cell
, vol.9
, pp. 536-544
-
-
Dai, D.F.1
Chen, T.2
Wanagat, J.3
Laflamme, M.4
Marcinek, D.J.5
Edmond, M.J.6
Ngo, C.P.7
Prolla, T.A.8
Rabinovitch, P.S.9
-
32
-
-
38349016262
-
Molecular mechanisms and potential clinical significante of S-glutathionylation
-
Dalle-Donne I, Milzani A, Gagliano N, Colombo R, Giustarini D, and Rossi R. Molecular mechanisms and potential clinical significante of S-glutathionylation. Antioxid Redox Signal 10: 445-473, 2008.
-
(2008)
Antioxid Redox Signal
, vol.10
, pp. 445-473
-
-
Dalle-Donne, I.1
Milzani, A.2
Gagliano, N.3
Colombo, R.4
Giustarini, D.5
Rossi, R.6
-
33
-
-
77951867859
-
Oxidative stress and Alzheimer's disease: Dietary polyphenols as potential therapeutic agents
-
Darvesh AS, Carroll RT, Bishayee A, Geldenhuys WJ, and Van der Schyf CJ. Oxidative stress and Alzheimer's disease: dietary polyphenols as potential therapeutic agents. Expert Rev Neurother 10: 729-745, 2010.
-
(2010)
Expert Rev Neurother
, vol.10
, pp. 729-745
-
-
Darvesh, A.S.1
Carroll, R.T.2
Bishayee, A.3
Geldenhuys, W.J.4
Van Der Schyf, C.J.5
-
34
-
-
34249846128
-
Resveratrol stimulates AMP kinase activity in neurons
-
Dasgupta B and Milbrandt J. Resveratrol stimulates AMP kinase activity in neurons. Proc Natl Acad Sci USA 104: 7217-7222, 2007.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 7217-7222
-
-
Dasgupta, B.1
Milbrandt, J.2
-
35
-
-
63849115360
-
Parthanatos, a messenger of death
-
David KK, Andrabi SA, Dawson TM, and Dawson VL. Parthanatos, a messenger of death. Front Biosci 14: 1116-1128, 2009.
-
(2009)
Front Biosci
, vol.14
, pp. 1116-1128
-
-
David, K.K.1
Andrabi, S.A.2
Dawson, T.M.3
Dawson, V.L.4
-
37
-
-
77955824765
-
An intimate liaison: Spatial organization of the endoplasmic reticulum-mitochondria relationship
-
de Brito OM and Scorrano L. An intimate liaison: spatial organization of the endoplasmic reticulum-mitochondria relationship. EMBO J 29: 2715-2723, 2010.
-
(2010)
EMBO J
, vol.29
, pp. 2715-2723
-
-
De Brito, O.M.1
Scorrano, L.2
-
38
-
-
44549086105
-
Epigallocatechin-gallate (EGCG) prevents mitochondrial damage in isoproterenol-induced cardiac toxicity in albino Wistar rats: A transmission electron microscopic and in vitro study
-
Devika PT and Stanely Mainzen Prince P. (-)Epigallocatechin-gallate (EGCG) prevents mitochondrial damage in isoproterenol-induced cardiac toxicity in albino Wistar rats: a transmission electron microscopic and in vitro study. Pharmacol Res 57: 351-357, 2008.
-
(2008)
Pharmacol Res
, vol.57
, pp. 351-357
-
-
Devika, P.T.1
Stanely Mainzen Prince, P.2
-
39
-
-
62249115660
-
Mitochondrial pathways for ROS formation and myocardial injury: The relevance of p66(Shc) and monoamine oxidase
-
Di Lisa F, Kaludercic N, Carpi A, Menabò R, and Giorgio M. Mitochondrial pathways for ROS formation and myocardial injury: the relevance of p66(Shc) and monoamine oxidase. Basic Res Cardiol 104: 131-139, 2009.
-
(2009)
Basic Res Cardiol
, vol.104
, pp. 131-139
-
-
Di Lisa, F.1
Kaludercic, N.2
Carpi, A.3
Menabò, R.4
Giorgio, M.5
-
40
-
-
79952786984
-
Mitochondrial targeting of vitamin e succinate enhances its pro-apoptotic and anti-cancer activity
-
Dong LF, Jameson VJ, Tilly D, Cerny J, Mahdavian E, Maŕn- Hernández A, Hernández-Esquivel L, Rodŕguez-Enŕquez S, Stursa J, Witting PK, Stantic B, Rohlena J, Truksa J, Kluckova K, Dyason JC, Ledvina M, Salvatore BA, Moreno-Sánchez R, Coster MJ, Ralph SJ, Smith RA, and Neuzil J. Mitochondrial targeting of vitamin E succinate enhances its pro-apoptotic and anti-cancer activity. J Biol Chem 286: 3717-3728, 2011.
-
(2011)
J Biol Chem
, vol.286
, pp. 3717-3728
-
-
Dong, L.F.1
Jameson, V.J.2
Tilly, D.3
Cerny, J.4
Mahdavian, E.5
Maŕn-Hernández, A.6
Hernández-Esquivel, L.7
Rodŕguez-Enŕquez, S.8
Stursa, J.9
Witting, P.K.10
Stantic, B.11
Rohlena, J.12
Truksa, J.13
Kluckova, K.14
Dyason, J.C.15
Ledvina, M.16
Salvatore, B.A.17
Moreno- Sánchez, R.18
Coster, M.J.19
Ralph, S.J.20
Smith, R.A.21
Neuzil, J.22
more..
-
41
-
-
47549092354
-
Alpha-tocopheryl succinate induces apoptosis by targeting ubiquinone-binding sites in mitochondrial respiratory complex II
-
Dong LF, Low P, Dyason JC, Wang XF, Prochazka L, Witting PK, Freeman R, Swettenham E, Valis K, Liu J, Zobalova R, Turanek J, Spitz DR, Domann FE, Scheffler IE, Ralph SJ, and Neuzil J. Alpha-tocopheryl succinate induces apoptosis by targeting ubiquinone-binding sites in mitochondrial respiratory complex II. Oncogene 27: 4324-4335, 2008.
-
(2008)
Oncogene
, vol.27
, pp. 4324-4335
-
-
Dong, L.F.1
Low, P.2
Dyason, J.C.3
Wang, X.F.4
Prochazka, L.5
Witting, P.K.6
Freeman, R.7
Swettenham, E.8
Valis, K.9
Liu, J.10
Zobalova, R.11
Turanek, J.12
Spitz, D.R.13
Domann, F.E.14
Scheffler, I.E.15
Ralph, S.J.16
Neuzil, J.17
-
42
-
-
37549019351
-
Vitamin e analogues inhibit angiogenesis by selective induction of apoptosis in proliferating endothelial cells: The role of oxidative stress
-
Dong LF, Swettenham E, Eliasson J, Wang XF, Gold M, Medunic Y, Stantic M, Low P, Prochazka L, Witting PK, Turanek J, Akporiaye ET, Ralph SJ, and Neuzil J. Vitamin E analogues inhibit angiogenesis by selective induction of apoptosis in proliferating endothelial cells: the role of oxidative stress. Cancer Res 67: 11906-11913, 2007.
-
(2007)
Cancer Res
, vol.67
, pp. 11906-11913
-
-
Dong, L.F.1
Swettenham, E.2
Eliasson, J.3
Wang, X.F.4
Gold, M.5
Medunic, Y.6
Stantic, M.7
Low, P.8
Prochazka, L.9
Witting, P.K.10
Turanek, J.11
Akporiaye, E.T.12
Ralph, S.J.13
Neuzil, J.14
-
43
-
-
67349189553
-
Resveratrol, a unique phytoalexin present in red wine, delivers either survival signal or death signal to the ischemic myocardium depending on dose
-
Dudley J, Das S, Mukherjee S, and Das DK. Resveratrol, a unique phytoalexin present in red wine, delivers either survival signal or death signal to the ischemic myocardium depending on dose. J Nutr Biochem 20: 443-452, 2009.
-
(2009)
J Nutr Biochem
, vol.20
, pp. 443-452
-
-
Dudley, J.1
Das, S.2
Mukherjee, S.3
Das, D.K.4
-
44
-
-
64449087671
-
Hypoxic activation of AMPK is dependent on mitochondrial ROS but independent of an increase in AMP/ATP ratio
-
Emerling BM, Weinberg F, Snyder C, Burgess Z, Mutlu GM, Viollet B, Budinger GR, and Chandel NS. Hypoxic activation of AMPK is dependent on mitochondrial ROS but independent of an increase in AMP/ATP ratio. Free Radic Biol Med 46: 1386-1391, 2009.
-
(2009)
Free Radic Biol Med
, vol.46
, pp. 1386-1391
-
-
Emerling, B.M.1
Weinberg, F.2
Snyder, C.3
Burgess, Z.4
Mutlu, G.M.5
Viollet, B.6
Budinger, G.R.7
Chandel, N.S.8
-
45
-
-
78249255217
-
A-Tocopherol is an effective phase II enzyme inducer: Protective effects on acrolein-induced oxidative stress and mitochondrial dysfunction in human retinal pigment epithelial cells
-
Feng Z, Liu Z, Li X, Jia H, Sun L, Tian C, Jia L, and Liu J. A-Tocopherol is an effective phase II enzyme inducer: protective effects on acrolein-induced oxidative stress and mitochondrial dysfunction in human retinal pigment epithelial cells. J Nutr Biochem 21: 1222-1231, 2010.
-
(2010)
J Nutr Biochem
, vol.21
, pp. 1222-1231
-
-
Feng, Z.1
Liu, Z.2
Li, X.3
Jia, H.4
Sun, L.5
Tian, C.6
Jia, L.7
Liu, J.8
-
46
-
-
69549091682
-
Metabolites are key to understanding health effects of wine polyphenolics
-
Forester SC and Waterhouse AL. Metabolites are key to understanding health effects of wine polyphenolics. J Nutr 139: 1824S-1831S, 2009.
-
(2009)
J Nutr
, vol.139
-
-
Forester, S.C.1
Waterhouse, A.L.2
-
47
-
-
77955906912
-
The mitochondrial bioenergetic capacity of carcinomas
-
Formentini L, Mart́nez-Reyes I, and Cuezva JM. The mitochondrial bioenergetic capacity of carcinomas. IUBMB Life 62: 554-560, 2010.
-
(2010)
IUBMB Life
, vol.62
, pp. 554-560
-
-
Formentini, L.1
Mart́nez-Reyes, I.2
Cuezva, J.M.3
-
48
-
-
77955467853
-
Morphine induces preconditioning via activation of mitochondrial K(Ca) channels
-
Frässdorf J, Huhn R, Niersmann C, Weber NC, Schlack W, Preckel B, and Hollmann MW. Morphine induces preconditioning via activation of mitochondrial K(Ca) channels. Can J Anaesth 57: 767-773, 2010.
-
(2010)
Can J Anaesth
, vol.57
, pp. 767-773
-
-
Frässdorf, J.1
Huhn, R.2
Niersmann, C.3
Weber, N.C.4
Schlack, W.5
Preckel, B.6
Hollmann, M.W.7
-
49
-
-
35948978460
-
Moving mitochondria: Establishing distribution of an essential organelle
-
Frederick RL and Shaw JM. Moving mitochondria: establishing distribution of an essential organelle. Traffic 8: 1668-1675, 2007.
-
(2007)
Traffic
, vol.8
, pp. 1668-1675
-
-
Frederick, R.L.1
Shaw, J.M.2
-
50
-
-
77955069772
-
Modulation of apoptosis by natural products for cancer therapy
-
Fulda S. Modulation of apoptosis by natural products for cancer therapy. Planta Med 76: 1075-1079, 2010.
-
(2010)
Planta Med
, vol.76
, pp. 1075-1079
-
-
Fulda, S.1
-
51
-
-
33746895175
-
Mitochondria as therapeutic targets for cancer chemotherapy
-
Galluzzi L, Larochette N, Zamzami N, and Kroemer G. Mitochondria as therapeutic targets for cancer chemotherapy. Oncogene 25: 4812-4830, 2006.
-
(2006)
Oncogene
, vol.25
, pp. 4812-4830
-
-
Galluzzi, L.1
Larochette, N.2
Zamzami, N.3
Kroemer, G.4
-
52
-
-
78149359658
-
Multistep and multitask Bax activation
-
Ghibelli L and Diederich M. Multistep and multitask Bax activation. Mitochondrion 10: 604-613, 2010.
-
(2010)
Mitochondrion
, vol.10
, pp. 604-613
-
-
Ghibelli, L.1
Diederich, M.2
-
53
-
-
71849095133
-
Cause and consequence: Mitochondrial dysfunction initiates and propagates neuronal dysfunction, neuronal death and behavioral abnormalities in age-associated neurodegenerative diseases
-
Gibson GE, Starkov A, Blass JP, Ratan RR, and Beal MF. Cause and consequence: mitochondrial dysfunction initiates and propagates neuronal dysfunction, neuronal death and behavioral abnormalities in age-associated neurodegenerative diseases. Biochim Biophys Acta 1802: 122-134, 2010.
-
(2010)
Biochim Biophys Acta
, vol.1802
, pp. 122-134
-
-
Gibson, G.E.1
Starkov, A.2
Blass, J.P.3
Ratan, R.R.4
Beal, M.F.5
-
54
-
-
77957656802
-
A matter of balance between life and death: Targeting reactive oxygen species (ROS)-induced autophagy for cancer therapy
-
Gibson SB. A matter of balance between life and death: targeting reactive oxygen species (ROS)-induced autophagy for cancer therapy. Autophagy 6: 835-837, 2010.
-
(2010)
Autophagy
, vol.6
, pp. 835-837
-
-
Gibson, S.B.1
-
55
-
-
22744447211
-
Electron transfer between cytochrome c and p66Shc generates reactive oxygen species that trigger mitochondrial apoptosis
-
Giorgio M, Migliaccio E, Orsini F, Paolucci D, Moroni M, Contursi C, Pelliccia G, Luzi L, Minucci S, Marcaccio M, Pinton P, Rizzuto R, Bernardi P, Paolucci F, and Pelicci PG. Electron transfer between cytochrome c and p66Shc generates reactive oxygen species that trigger mitochondrial apoptosis. Cell 122: 221-233, 2005.
-
(2005)
Cell
, vol.122
, pp. 221-233
-
-
Giorgio, M.1
Migliaccio, E.2
Orsini, F.3
Paolucci, D.4
Moroni, M.5
Contursi, C.6
Pelliccia, G.7
Luzi, L.8
Minucci, S.9
Marcaccio, M.10
Pinton, P.11
Rizzuto, R.12
Bernardi, P.13
Paolucci, F.14
Pelicci, P.G.15
-
56
-
-
84867350387
-
Review of molecular mechanisms involved in the activation of the Nrf2-ARE signaling pathway by chemopreventive agents
-
Giudice A, Arra C, and Turco MC. Review of molecular mechanisms involved in the activation of the Nrf2-ARE signaling pathway by chemopreventive agents. Methods Mol Biol 647: 37-74, 2010.
-
(2010)
Methods Mol Biol
, vol.647
, pp. 37-74
-
-
Giudice, A.1
Arra, C.2
Turco, M.C.3
-
57
-
-
35348865444
-
Mechanism of inhibition of bovine F1-ATPase by resveratrol and related polyphenols
-
Gledhill JR, Montgomery MG, Leslie AG, and Walker JE. Mechanism of inhibition of bovine F1-ATPase by resveratrol and related polyphenols. Proc Natl Acad Sci USA 104: 13632-13637, 2007.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 13632-13637
-
-
Gledhill, J.R.1
Montgomery, M.G.2
Leslie, A.G.3
Walker, J.E.4
-
59
-
-
50949115617
-
High levels of Fis1, a pro-fission mitochondrial protein, trigger autophagy
-
Gomes LC and Scorrano L. High levels of Fis1, a pro-fission mitochondrial protein, trigger autophagy. Biochim Biophys Acta 1777: 860-866, 2008.
-
(2008)
Biochim Biophys Acta
, vol.1777
, pp. 860-866
-
-
Gomes, L.C.1
Scorrano, L.2
-
60
-
-
3442886811
-
The pathophysiology of mitochondrial cell death
-
Green DR and Kroemer G. The pathophysiology of mitochondrial cell death. Science 305: 626-629, 2004.
-
(2004)
Science
, vol.305
, pp. 626-629
-
-
Green, D.R.1
Kroemer, G.2
-
61
-
-
79959534486
-
Oxidative protein damage and the proteasome
-
[Epub ahead of print]; DOI 10.1007/s00726-010-0646-8
-
Grimm S, Höhn A, and Grune T. Oxidative protein damage and the proteasome. Amino Acids 2011, [Epub ahead of print]; DOI. 10.1007/s00726-010- 0646-8
-
(2011)
Amino Acids
-
-
Grimm, S.1
Höhn, A.2
Grune, T.3
-
62
-
-
77954936520
-
Calpain and caspase orchestrated death signal to accomplish apoptosis induced by resveratrol and its novel analog hydroxystilbene-1 in cancer cells
-
Guha P, Dey A, Dhyani MV, Sen R, Chatterjee M, Chattopadhyay S, and Bandyopadhyay SK. Calpain and caspase orchestrated death signal to accomplish apoptosis induced by resveratrol and its novel analog hydroxystilbene-1 in cancer cells. J Pharmacol Exp Ther 334: 381-394, 2010.
-
(2010)
J Pharmacol Exp Ther
, vol.334
, pp. 381-394
-
-
Guha, P.1
Dey, A.2
Dhyani, M.V.3
Sen, R.4
Chatterjee, M.5
Chattopadhyay, S.6
Bandyopadhyay, S.K.7
-
63
-
-
77957592789
-
Regulation of survival, proliferation, invasion, angiogenesis, and metastasis of tumor cells through modulation of inflammatory pathways by nutraceuticals
-
Gupta SC, Kim JH, Prasad S, and Aggarwal BB. Regulation of survival, proliferation, invasion, angiogenesis, and metastasis of tumor cells through modulation of inflammatory pathways by nutraceuticals. Cancer Metastasis Rev 29: 405-434, 2010.
-
(2010)
Cancer Metastasis Rev
, vol.29
, pp. 405-434
-
-
Gupta, S.C.1
Kim, J.H.2
Prasad, S.3
Aggarwal, B.B.4
-
64
-
-
77949357437
-
Cardioprotection by resveratrol: A novel mechanism via autophagy involving the mTORC2 pathway
-
Gurusamy N, Lekli I, Mukherjee S, Ray D, Ahsan MK, Gherghiceanu M, Popescu LM, and Das DK. Cardioprotection by resveratrol: a novel mechanism via autophagy involving the mTORC2 pathway. Cardiovasc Res 86: 103-112, 2010.
-
(2010)
Cardiovasc Res
, vol.86
, pp. 103-112
-
-
Gurusamy, N.1
Lekli, I.2
Mukherjee, S.3
Ray, D.4
Ahsan, M.K.5
Gherghiceanu, M.6
Popescu, L.M.7
Das, D.K.8
-
65
-
-
68649090703
-
The role of the mitochondrial permeability transition pore in heart disease
-
Halestrap AP and Pasdois P. The role of the mitochondrial permeability transition pore in heart disease. Biochim Biophys Acta 1787: 1402-1415, 2009.
-
(2009)
Biochim Biophys Acta
, vol.1787
, pp. 1402-1415
-
-
Halestrap, A.P.1
Pasdois, P.2
-
66
-
-
48349140474
-
Are polyphenols antioxidants or pro-oxidants? What do we learn from cell culture and in vivo studies?
-
Halliwell B. Are polyphenols antioxidants or pro-oxidants? What do we learn from cell culture and in vivo studies? Arch Biochem Biophys 476: 107-112, 2008.
-
(2008)
Arch Biochem Biophys
, vol.476
, pp. 107-112
-
-
Halliwell, B.1
-
67
-
-
77953807035
-
Hydroxytyrosol promotes mitochondrial biogenesis and mitochondrial function in 3T3-L1 adipocytes
-
Hao J, Shen W, Yu G, Jia H, Li X, Feng Z, Wang Y, Weber P, Wertz K, Sharman E, and Liu J. Hydroxytyrosol promotes mitochondrial biogenesis and mitochondrial function in 3T3-L1 adipocytes. J Nutr Biochem 21: 634-644, 2010.
-
(2010)
J Nutr Biochem
, vol.21
, pp. 634-644
-
-
Hao, J.1
Shen, W.2
Yu, G.3
Jia, H.4
Li, X.5
Feng, Z.6
Wang, Y.7
Weber, P.8
Wertz, K.9
Sharman, E.10
Liu, J.11
-
68
-
-
43549088782
-
Resveratrol: A multitargeted agent for age-associated chronic diseases
-
Harikumar KB and Aggarwal BB. Resveratrol: a multitargeted agent for age-associated chronic diseases. Cell Cycle 7: 1020-1035, 2008.
-
(2008)
Cell Cycle
, vol.7
, pp. 1020-1035
-
-
Harikumar, K.B.1
Aggarwal, B.B.2
-
69
-
-
0142213542
-
The free radical theory of aging
-
Harman D. The free radical theory of aging. Antioxid Redox Signal 5: 557-561, 2003.
-
(2003)
Antioxid Redox Signal
, vol.5
, pp. 557-561
-
-
Harman, D.1
-
70
-
-
62249102192
-
The mitochondrial permeability transition pore as a target for preconditioning and postconditioning
-
Hausenloy DJ, Ong SB, and Yellon DM. The mitochondrial permeability transition pore as a target for preconditioning and postconditioning. Basic Res Cardiol 104: 189-202, 2009.
-
(2009)
Basic Res Cardiol
, vol.104
, pp. 189-202
-
-
Hausenloy, D.J.1
Ong, S.B.2
Yellon, D.M.3
-
71
-
-
77955380974
-
Mitochondrial DNA mutations induce mitochondrial dysfunction, apoptosis and sarcopenia in skeletal muscle of mitochondrial DNA mutator mice
-
Hiona A, Sanz A, Kujoth GC, Pamplona R, Seo AY, Hofer T, Someya S, Miyakawa T, Nakayama C, Samhan-Arias AK, Servais S, Barger JL, Portero-Ot́n M, Tanokura M, Prolla TA, and Leeuwenburgh C. Mitochondrial DNA mutations induce mitochondrial dysfunction, apoptosis and sarcopenia in skeletal muscle of mitochondrial DNA mutator mice. PLoS One 5: e11468, 2010.
-
(2010)
PLoS One
, vol.5
-
-
Hiona, A.1
Sanz, A.2
Kujoth, G.C.3
Pamplona, R.4
Seo, A.Y.5
Hofer, T.6
Someya, S.7
Miyakawa, T.8
Nakayama, C.9
Samhan-Arias, A.K.10
Servais, S.11
Barger, J.L.12
Portero-Ot́n, M.13
Tanokura, M.14
Prolla, T.A.15
Leeuwenburgh, C.16
-
72
-
-
64049109356
-
Quercetin and its derivatives: Synthesis, pharmacological uses with special emphasis on anti-tumor properties and prodrug with enhanced bio-availability
-
Hirpara KV, Aggarwal P, Mukherjee AJ, Joshi N, and Burman AC. Quercetin and its derivatives: synthesis, pharmacological uses with special emphasis on anti-tumor properties and prodrug with enhanced bio-availability. Anticancer Agents Med Chem 9: 138-161, 2009.
-
(2009)
Anticancer Agents Med Chem
, vol.9
, pp. 138-161
-
-
Hirpara, K.V.1
Aggarwal, P.2
Mukherjee, A.J.3
Joshi, N.4
Burman, A.C.5
-
73
-
-
77953810265
-
Regulation of mitochondrial fission by intracellular Ca2 + in rat ventricular myocytes
-
Hom J, Yu T, Yoon Y, Porter G, and Sheu SS. Regulation of mitochondrial fission by intracellular Ca2 + in rat ventricular myocytes. Biochim Biophys Acta 1797: 913-921, 2010.
-
(2010)
Biochim Biophys Acta
, vol.1797
, pp. 913-921
-
-
Hom, J.1
Yu, T.2
Yoon, Y.3
Porter, G.4
Sheu, S.S.5
-
74
-
-
0141719702
-
Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan
-
Howitz KT, Bitterman KJ, Cohen HY, Lamming DW, Lavu S, Wood JG, Zipkin RE, Chung P, Kisielewski A, Zhang LL, Scherer B, and Sinclair DA. Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan. Nature 425: 191-196, 2003.
-
(2003)
Nature
, vol.425
, pp. 191-196
-
-
Howitz, K.T.1
Bitterman, K.J.2
Cohen, H.Y.3
Lamming, D.W.4
Lavu, S.5
Wood, J.G.6
Zipkin, R.E.7
Chung, P.8
Kisielewski, A.9
Zhang, L.L.10
Scherer, B.11
Sinclair, D.A.12
-
75
-
-
58549119989
-
Catechin, green tea component, causes caspase-independent necrosis-like cell death in chronic myelogenous leukemia
-
Iwasaki R, Ito K, Ishida T, Hamanoue M, Adachi S, Watanabe T, and Sato Y. Catechin, green tea component, causes caspase-independent necrosis-like cell death in chronic myelogenous leukemia. Cancer Sci 100: 349-356, 2009.
-
(2009)
Cancer Sci
, vol.100
, pp. 349-356
-
-
Iwasaki, R.1
Ito, K.2
Ishida, T.3
Hamanoue, M.4
Adachi, S.5
Watanabe, T.6
Sato, Y.7
-
76
-
-
65649137735
-
Chemoprotective mechanism of the natural compounds, epigallocatechin-3-O- gallate, quercetin and curcumin against cancer and cardiovascular diseases
-
Jagtap S, Meganathan K, Wagh V, Winkler J, Hescheler J, and Sachinidis A. Chemoprotective mechanism of the natural compounds, epigallocatechin-3-O- gallate, quercetin and curcumin against cancer and cardiovascular diseases. Curr Med Chem 16: 1451-1462, 2009.
-
(2009)
Curr Med Chem
, vol.16
, pp. 1451-1462
-
-
Jagtap, S.1
Meganathan, K.2
Wagh, V.3
Winkler, J.4
Hescheler, J.5
Sachinidis, A.6
-
77
-
-
0037094386
-
Autoschizis: A novel cell death
-
Jamison JM, Gilloteaux J, Taper HS, Calderon PB, and Summers JL. Autoschizis: a novel cell death. Biochem Pharmacol 63: 1773-1783, 2002.
-
(2002)
Biochem Pharmacol
, vol.63
, pp. 1773-1783
-
-
Jamison, J.M.1
Gilloteaux, J.2
Taper, H.S.3
Calderon, P.B.4
Summers, J.L.5
-
78
-
-
77649337197
-
Distinctions and similarities of cell bioenergetics and the role of mitochondria in hypoxia, cancer, and embryonic development
-
Jezek P, Plecitá-Hlavatá L, Smolková K, and Rossignol R. Distinctions and similarities of cell bioenergetics and the role of mitochondria in hypoxia, cancer, and embryonic development. Int J Biochem Cell Biol 42: 604-622, 2010.
-
(2010)
Int J Biochem Cell Biol
, vol.42
, pp. 604-622
-
-
Jezek, P.1
Plecitá-Hlavatá, L.2
Smolková, K.3
Rossignol, R.4
-
79
-
-
77949595310
-
Autophagic and apoptotic mechanisms of curcumin-induced death in K562 cells
-
Jia YL, Li J, Qin ZH, and Liang ZQ. Autophagic and apoptotic mechanisms of curcumin-induced death in K562 cells. J Asian Nat Prod Res 11: 918-928, 2009.
-
(2009)
J Asian Nat Prod Res
, vol.11
, pp. 918-928
-
-
Jia, Y.L.1
Li, J.2
Zh, Q.3
Liang, Z.Q.4
-
80
-
-
56149119401
-
Neuroprotective effect of resveratrol on 6-OHDA-induced Parkinson's disease in rats
-
Jin F, Wu Q, Lu YF, Gong QH, and Shi JS. Neuroprotective effect of resveratrol on 6-OHDA-induced Parkinson's disease in rats. Eur J Pharmacol 600: 78-82, 2008.
-
(2008)
Eur J Pharmacol
, vol.600
, pp. 78-82
-
-
Jin, F.1
Wu, Q.2
Lu, Y.F.3
Gong, Q.H.4
Shi, J.S.5
-
81
-
-
77952096424
-
Regulation of insulin secretion: Role of mitochondrial signalling
-
Jitrapakdee S, Wutthisathapornchai A, Wallace JC, and MacDonald MJ. Regulation of insulin secretion: role of mitochondrial signalling. Diabetologia 53: 1019-1032, 2010.
-
(2010)
Diabetologia
, vol.53
, pp. 1019-1032
-
-
Jitrapakdee, S.1
Wutthisathapornchai, A.2
Wallace, J.C.3
MacDonald, M.J.4
-
82
-
-
77955292017
-
Role of autophagy in diabetes and mitochondria
-
Jung HS and Lee MS. Role of autophagy in diabetes and mitochondria. Ann NY Acad Sci 1201: 79-83, 2010.
-
(2010)
Ann NY Acad Sci
, vol.1201
, pp. 79-83
-
-
Jung, H.S.1
Lee, M.S.2
-
83
-
-
77952480033
-
Role of reactive oxygen species in the progression of type 2 diabetes and atherosclerosis
-
453892
-
Kaneto H, Katakami N, Matsuhisa M, and Matsuoka TA. Role of reactive oxygen species in the progression of type 2 diabetes and atherosclerosis. Mediators Inflamm 2010: 453892, 2010.
-
Mediators Inflamm
, vol.2010
, pp. 2010
-
-
Kaneto, H.1
Katakami, N.2
Matsuhisa, M.3
Matsuoka, T.A.4
-
84
-
-
77958140445
-
Mitochondria on guard: Role of mitochondrial fusion and fission in the regulation of apoptosis
-
Karbowski M. Mitochondria on guard: role of mitochondrial fusion and fission in the regulation of apoptosis. Adv Exp Med Biol 687: 131-142, 2010.
-
(2010)
Adv Exp Med Biol
, vol.687
, pp. 131-142
-
-
Karbowski, M.1
-
85
-
-
2442423309
-
Dimerization and processing of procaspase-9 by redox stress in mitochondria
-
Katoh I, Tomimori Y, Ikawa Y, and Kurata S. Dimerization and processing of procaspase-9 by redox stress in mitochondria. J Biol Chem 279: 15515-15523, 2004.
-
(2004)
J Biol Chem
, vol.279
, pp. 15515-15523
-
-
Katoh, I.1
Tomimori, Y.2
Ikawa, Y.3
Kurata, S.4
-
86
-
-
79955689719
-
Resveratrol metabolites do not elicit early pro-apoptotic mechanisms in neuroblastoma cells
-
Kenealey JD, Subramanian L, van Ginkel P, Darjatmoko S, Lindstrom M, Somoza V, Ghosh S, Song Z, Hsung R, Kwon GS, Eliceiri K, Albert D, and Polans A. Resveratrol metabolites do not elicit early pro-apoptotic mechanisms in neuroblastoma cells. J Agric Food Chem 59: 4979-4986, 2011.
-
(2011)
J Agric Food Chem
, vol.59
, pp. 4979-4986
-
-
Kenealey, J.D.1
Subramanian, L.2
Van Ginkel, P.3
Darjatmoko, S.4
Lindstrom, M.5
Somoza, V.6
Ghosh, S.7
Song, Z.8
Hsung, R.9
Kwon, G.S.10
Eliceiri, K.11
Albert, D.12
Polans, A.13
-
87
-
-
77449090086
-
Apoptosis by dietary agents for prevention and treatment of prostate cancer
-
Khan N, Adhami VM, and Mukhtar H. Apoptosis by dietary agents for prevention and treatment of prostate cancer. Endocr Relat Cancer 17: R39-R52, 2010.
-
(2010)
Endocr Relat Cancer
, vol.17
-
-
Khan, N.1
Adhami, V.M.2
Mukhtar, H.3
-
88
-
-
34447308268
-
SIRT1 deacetylase protects against neurodegeneration in models for Alzheimer's disease and amyotrophic lateral sclerosis
-
Kim D, Nguyen MD, Dobbin MM, Fischer A, Sananbenesi F, Rodgers JT, Delalle I, Baur JA, Sui G, Armour SM, Puigserver P, Sinclair DA, and Tsai LH. SIRT1 deacetylase protects against neurodegeneration in models for Alzheimer's disease and amyotrophic lateral sclerosis. EMBO J 26: 3169-3179, 2007.
-
(2007)
EMBO J
, vol.26
, pp. 3169-3179
-
-
Kim, D.1
Nguyen, M.D.2
Dobbin, M.M.3
Fischer, A.4
Sananbenesi, F.5
Rodgers, J.T.6
Delalle, I.7
Baur, J.A.8
Sui, G.9
Armour, S.M.10
Puigserver, P.11
Sinclair, D.A.12
Tsai, L.H.13
-
90
-
-
77349084360
-
Naturally occurring phytochemicals for the prevention of Alzheimer's disease
-
Kim J, Lee HJ, and Lee KW. Naturally occurring phytochemicals for the prevention of Alzheimer's disease. J Neurochem 112: 1415-1430, 2010.
-
(2010)
J Neurochem
, vol.112
, pp. 1415-1430
-
-
Kim, J.1
Lee, H.J.2
Lee, K.W.3
-
91
-
-
69249240216
-
Efficacy of sauchinone as a novel AMPK-activating lignan for preventing iron-induced oxidative stress and liver injury
-
Kim YW, Lee SM, Shin SM, Hwang SJ, Brooks JS, Kang HE, Lee MG, Kim SC, and Kim SG. Efficacy of sauchinone as a novel AMPK-activating lignan for preventing iron-induced oxidative stress and liver injury. Free Radic Biol Med 47: 1082-1092, 2009.
-
(2009)
Free Radic Biol Med
, vol.47
, pp. 1082-1092
-
-
Kim, Y.W.1
Lee, S.M.2
Shin, S.M.3
Hwang, S.J.4
Brooks, J.S.5
Kang, H.E.6
Lee, M.G.7
Kim, S.C.8
Kim, S.G.9
-
92
-
-
4744341871
-
Advanced cancers: Eradication in all cases using 3-bromopyruvate therapy to deplete ATP
-
Ko YH, Smith BL, Wang Y, Pomper MG, Rini DA, Torbenson MS, Hullihen J, and Pedersen PL. Advanced cancers: eradication in all cases using 3-bromopyruvate therapy to deplete ATP. Biochem Biophys Res Commun 324: 269-275, 2004.
-
(2004)
Biochem Biophys Res Commun
, vol.324
, pp. 269-275
-
-
Ko, Y.H.1
Smith, B.L.2
Wang, Y.3
Pomper, M.G.4
Rini, D.A.5
Torbenson, M.S.6
Hullihen, J.7
Pedersen, P.L.8
-
93
-
-
0035917814
-
Mitochondrial permeability transition and oxidative stress
-
Kowaltowski AJ, Castilho RF, and Vercesi AE. Mitochondrial permeability transition and oxidative stress. FEBS Lett 495: 12-15, 2001.
-
(2001)
FEBS Lett
, vol.495
, pp. 12-15
-
-
Kowaltowski, A.J.1
Castilho, R.F.2
Vercesi, A.E.3
-
94
-
-
22344456832
-
Mitochondrial DNA mutations, oxidative stress, and apoptosis in mammalian aging
-
Kujoth GC, Hiona A, Pugh TD, Someya S, Panzer K, Wohlgemuth SE, Hofer T, Seo AY, Sullivan R, Jobling WA, Morrow JD, Van Remmen H, Sedivy JM, Yamasoba T, Tanokura M, Weindruch R, Leeuwenburgh C, and Prolla TA. Mitochondrial DNA mutations, oxidative stress, and apoptosis in mammalian aging. Science 309: 481-484, 2005.
-
(2005)
Science
, vol.309
, pp. 481-484
-
-
Kujoth, G.C.1
Hiona, A.2
Pugh, T.D.3
Someya, S.4
Panzer, K.5
Wohlgemuth, S.E.6
Hofer, T.7
Seo, A.Y.8
Sullivan, R.9
Jobling, W.A.10
Morrow, J.D.11
Van Remmen, H.12
Sedivy, J.M.13
Yamasoba, T.14
Tanokura, M.15
Weindruch, R.16
Leeuwenburgh, C.17
Prolla, T.A.18
-
95
-
-
33748310632
-
Effect of resveratrol on 3-nitropropionic acid-induced biochemical and behavioural changes: Possible neuroprotective mechanisms
-
Kumar P, Padi SS, Naidu PS, and Kumar A. Effect of resveratrol on 3-nitropropionic acid-induced biochemical and behavioural changes: possible neuroprotective mechanisms. Behav Pharmacol 17: 485-492, 2006.
-
(2006)
Behav Pharmacol
, vol.17
, pp. 485-492
-
-
Kumar, P.1
Padi, S.S.2
Naidu, P.S.3
Kumar, A.4
-
96
-
-
51349132313
-
Cancer chemopreventive and therapeutic potential of resveratrol: Mechanistic perspectives
-
Kundu JK and Surh YJ. Cancer chemopreventive and therapeutic potential of resveratrol: mechanistic perspectives. Cancer Lett 269: 243-261, 2008.
-
(2008)
Cancer Lett
, vol.269
, pp. 243-261
-
-
Kundu, J.K.1
Surh, Y.J.2
-
97
-
-
77953534370
-
A novel chalcone from Alpinia pricei Hayata with potent apoptotic activity: Involvement of ROS and GADD153 upstream of mitochondria-dependent apoptosis in HCT116 cells
-
Kuo YF, Su YZ, Tseng YH, Wang SY, Wang HM, and Chueh PJ. Flavokawain B, a novel chalcone from Alpinia pricei Hayata with potent apoptotic activity: Involvement of ROS and GADD153 upstream of mitochondria-dependent apoptosis in HCT116 cells. Free Radic Biol Med 49: 214-226, 2010.
-
(2010)
Free Radic Biol Med
, vol.49
, pp. 214-226
-
-
Kuo, Y.F.1
Su, Y.Z.2
Tseng, Y.H.3
Wang, S.Y.4
Wang, H.M.5
Chueh, P.J.6
Flavokawain, B.7
-
98
-
-
77954519532
-
Redox activity within the lysosomal compartment: Implications for aging and apoptosis
-
Kurz T, Eaton JW, and Brunk UT. Redox activity within the lysosomal compartment: implications for aging and apoptosis. Antioxid Redox Signal 13: 511-523, 2010.
-
(2010)
Antioxid Redox Signal
, vol.13
, pp. 511-523
-
-
Kurz, T.1
Eaton, J.W.2
Brunk, U.T.3
-
99
-
-
33845399894
-
Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1a
-
Lagouge M, Argmann C, Gerhart-Hines Z, Meziane H, Lerin C, Daussin F, Messadeq N, Milne J, Lambert P, Elliott P, Geny B, Laakso M, Puigserver P, and Auwerx J. Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1a. Cell 127: 1109-1122, 2006.
-
(2006)
Cell
, vol.127
, pp. 1109-1122
-
-
Lagouge, M.1
Argmann, C.2
Gerhart-Hines, Z.3
Meziane, H.4
Lerin, C.5
Daussin, F.6
Messadeq, N.7
Milne, J.8
Lambert, P.9
Elliott, P.10
Geny, B.11
Laakso, M.12
Puigserver, P.13
Auwerx, J.14
-
100
-
-
77956178353
-
The antioxidant and pro-oxidant activities of green tea polyphenols: A role in cancer prevention
-
Lambert JD and Elias RJ. The antioxidant and pro-oxidant activities of green tea polyphenols: a role in cancer prevention. Arch Biochem Biophys 501: 65-72, 2010.
-
(2010)
Arch Biochem Biophys
, vol.501
, pp. 65-72
-
-
Lambert, J.D.1
Elias, R.J.2
-
101
-
-
37549017270
-
Biotransformation of gree tea polyphenols and the biological activities of those metabolites
-
Lambert JD, Sang S, and Yang CS. Biotransformation of gree tea polyphenols and the biological activities of those metabolites. Mol Pharm 4: 819-825, 2007.
-
(2007)
Mol Pharm
, vol.4
, pp. 819-825
-
-
Lambert, J.D.1
Sang, S.2
Yang, C.S.3
-
102
-
-
73749085674
-
When a theory of aging ages badly
-
Lapointe J and Hekimi S. When a theory of aging ages badly. Cell Mol Life Sci 67: 1-8, 2010.
-
(2010)
Cell Mol Life Sci
, vol.67
, pp. 1-8
-
-
Lapointe, J.1
Hekimi, S.2
-
103
-
-
2442641693
-
Nutritional factors and risk of incident dementia in the PAQUID longitudinal cohort
-
Larrieu S, Letenneur L, Helmer C, Dartigues JF, and Barberger-Gateau P. Nutritional factors and risk of incident dementia in the PAQUID longitudinal cohort. J Nutr Health Aging 8: 150-154, 2004.
-
(2004)
J Nutr Health Aging
, vol.8
, pp. 150-154
-
-
Larrieu, S.1
Letenneur, L.2
Helmer, C.3
Dartigues, J.F.4
Barberger-Gateau, P.5
-
104
-
-
78049528044
-
Tea catechins as inhibitors of receptor tyrosine kinases: Mechanistic insights and human relevance
-
Larsen CA, Dashwood RH, and Bisson WH. Tea catechins as inhibitors of receptor tyrosine kinases: mechanistic insights and human relevance. Pharmacol Res 62: 457-464, 2010.
-
(2010)
Pharmacol Res
, vol.62
, pp. 457-464
-
-
Larsen, C.A.1
Dashwood, R.H.2
Bisson, W.H.3
-
105
-
-
77953627194
-
Somatic mitochondrial DNA mutations in mammalian aging
-
Larsson NG. Somatic mitochondrial DNA mutations in mammalian aging. Annu Rev Biochem 79: 683-706, 2010.
-
(2010)
Annu Rev Biochem
, vol.79
, pp. 683-706
-
-
Larsson, N.G.1
-
106
-
-
33845273100
-
Pro-oxidant activity of flavonoids induces EpRE-mediated gene expression
-
Lee-Hilz YY, Boerboom AM, Westphal AH, Berkel WJ, Aarts JM, and Rietjens IM. Pro-oxidant activity of flavonoids induces EpRE-mediated gene expression. Chem Res Toxicol 19: 1499-1505, 2006.
-
(2006)
Chem Res Toxicol
, vol.19
, pp. 1499-1505
-
-
Lee-Hilz, Y.Y.1
Boerboom, A.M.2
Westphal, A.H.3
Berkel, W.J.4
Aarts, J.M.5
Rietjens, I.M.6
-
107
-
-
77957318944
-
Glucose regulation of b-cell stress in type 2 diabetes
-
Leibowitz G, Bachar E, Shaked M, Sinai A, Ketzinel-Gilad M, Cerasi E, and Kaiser N. Glucose regulation of b-cell stress in type 2 diabetes. Diabetes Obes Metab 12 Suppl 2: 66-75, 2010.
-
(2010)
Diabetes Obes Metab 12 Suppl
, vol.2
, pp. 66-75
-
-
Leibowitz, G.1
Bachar, E.2
Shaked, M.3
Sinai, A.4
Ketzinel-Gilad, M.5
Cerasi, E.6
Kaiser, N.7
-
108
-
-
77249122561
-
Design and development of nanovehicle-based delivery systems for preventive or therapeutic supplementation with flavonoids
-
Leonarduzzi G, Testa G, Sottero B, Gamba P, and Poli G. Design and development of nanovehicle-based delivery systems for preventive or therapeutic supplementation with flavonoids. Curr Med Chem 17: 74-95, 2010.
-
(2010)
Curr Med Chem
, vol.17
, pp. 74-95
-
-
Leonarduzzi, G.1
Testa, G.2
Sottero, B.3
Gamba, P.4
Poli, G.5
-
109
-
-
78751672975
-
Autophagy in immunity and inflammation
-
Levine B, Mizushima N, and Virgin HW. Autophagy in immunity and inflammation. Nature 469: 323-335, 2011.
-
(2011)
Nature
, vol.469
, pp. 323-335
-
-
Levine, B.1
Mizushima, N.2
Virgin, H.W.3
-
110
-
-
79958120468
-
GADD45a and annexin A1 are involved in the apoptosis of HL-60 induced by resveratrol
-
Li G, He S, Chang L, Lu H, Zhang H, Zhang H, and Chiu J. GADD45a and annexin A1 are involved in the apoptosis of HL-60 induced by resveratrol. Phytomedicine 18: 704-709, 2011.
-
(2011)
Phytomedicine
, vol.18
, pp. 704-709
-
-
Li, G.1
He, S.2
Chang, L.3
Lu, H.4
Zhang, H.5
Zhang, H.6
Chiu, J.7
-
111
-
-
73949119606
-
And Wong-Riley MT. p38 mitogenactivated protein kinase and calcium channels mediate signaling in depolarization-induced activation of peroxisome proliferator-activated receptor gamma coactivator-1a in neurons
-
Liang HL, Dhar SS, and Wong-Riley MT. p38 mitogenactivated protein kinase and calcium channels mediate signaling in depolarization-induced activation of peroxisome proliferator-activated receptor gamma coactivator-1a in neurons. J Neurosci Res 88: 640-649, 2010.
-
(2010)
J Neurosci Res
, vol.88
, pp. 640-649
-
-
Liang, H.L.1
Dhar, S.S.2
-
112
-
-
78851471132
-
Resveratrol and apoptosis
-
Lin HY, Tang HY, Davis FB, and Davis PJ. Resveratrol and apoptosis. Ann NY Acad Sci 1215: 79-88, 2011.
-
(2011)
Ann NY Acad Sci
, vol.1215
, pp. 79-88
-
-
Lin, H.Y.1
Tang, H.Y.2
Davis, F.B.3
Davis, P.J.4
-
113
-
-
33750347347
-
Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases
-
Lin MT and Beal MF. Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases. Nature 443: 787-795, 2006.
-
(2006)
Nature
, vol.443
, pp. 787-795
-
-
Lin, M.T.1
Beal, M.F.2
-
114
-
-
77954909425
-
PGC-1a regulation by exercise training and its influences on muscle function and insulin sensitivity
-
Lira VA, Benton CR, Yan Z, and Bonen A. PGC-1a regulation by exercise training and its influences on muscle function and insulin sensitivity. Am J Physiol Endocrinol Metab 299: E145-E161, 2010.
-
(2010)
Am J Physiol Endocrinol Metab
, vol.299
-
-
Lira, V.A.1
Benton, C.R.2
Yan, Z.3
Bonen, A.4
-
115
-
-
75449090789
-
Anticancer agents derived from natural products
-
Liu EH, Qi LW, Wu Q, Peng YB, and Li P. Anticancer agents derived from natural products. Mini Rev Med Chem 9: 1547-1555, 2009.
-
(2009)
Mini Rev Med Chem
, vol.9
, pp. 1547-1555
-
-
Liu, E.H.1
Qi, L.W.2
Wu, Q.3
Peng, Y.B.4
Li, P.5
-
116
-
-
77649135478
-
A new view of carcinogenesis and an alternative approach to cancer therapy
-
López-Lázaro M. A new view of carcinogenesis and an alternative approach to cancer therapy. Mol Med 16: 144-153, 2010.
-
(2010)
Mol Med
, vol.16
, pp. 144-153
-
-
López-Lázaro, M.1
-
117
-
-
51649086475
-
Neuroprotective effects of resveratrol on MPTP-induced neuron loss mediated by free radical scavenging
-
Lu KT, Ko MC, Chen BY, Huang JC, Hsieh CW, Lee MC, Chiou RY, Wung BS, Peng CH, and Yang YL. Neuroprotective effects of resveratrol on MPTP-induced neuron loss mediated by free radical scavenging. J Agric Food Chem 56: 6910-6913, 2008.
-
(2008)
J Agric Food Chem
, vol.56
, pp. 6910-6913
-
-
Lu, K.T.1
Ko, M.C.2
Chen, B.Y.3
Huang, J.C.4
Hsieh, C.W.5
Lee, M.C.6
Chiou, R.Y.7
Wung, B.S.8
Peng, C.H.9
Yang, Y.L.10
-
118
-
-
77954578686
-
Antidiabetic effects of total flavonoids from Litsea Coreana leaf on fat-fed, streptozoticin-induced type 2 diabetic rats
-
Lu YX, Zhang Q, Li J, Sun YX, Wang LY, Cheng WM, and Hu XY. Antidiabetic effects of total flavonoids from Litsea Coreana leaf on fat-fed, streptozoticin-induced type 2 diabetic rats. Am J Chin Med 38: 713-725, 2010.
-
(2010)
Am J Chin Med
, vol.38
, pp. 713-725
-
-
Lu, Y.X.1
Zhang, Q.2
Li, J.3
Sun, Y.X.4
Wang, L.Y.5
Cheng, W.M.6
Hu, X.Y.7
-
120
-
-
77951697106
-
Multifactorial anticancer effects of digalloyl-resveratrol encompass apoptosis, cell-cycle arrest, and inhibition of lymphendothelial gap formation in vitro
-
Madlener S, Saiko P, Vonach C, Viola K, Huttary N, Stark N, Popescu R, Gridling M, Vo NT, Herbacek I, Davidovits A, Giessrigl B, Venkateswarlu S, Geleff S, Jäger W, Grusch M, Kerjaschki D, Mikulits W, Golakoti T, Fritzer-Szekeres M, Szekeres T, and Krupitza G. Multifactorial anticancer effects of digalloyl-resveratrol encompass apoptosis, cell-cycle arrest, and inhibition of lymphendothelial gap formation in vitro. Br J Cancer 102: 1361-1370, 2010.
-
(2010)
Br J Cancer
, vol.102
, pp. 1361-1370
-
-
Madlener, S.1
Saiko, P.2
Vonach, C.3
Viola, K.4
Huttary, N.5
Stark, N.6
Popescu, R.7
Gridling, M.8
Vo, N.T.9
Herbacek, I.10
Davidovits, A.11
Giessrigl, B.12
Venkateswarlu, S.13
Geleff, S.14
Jäger, W.15
Grusch, M.16
Kerjaschki, D.17
Mikulits, W.18
Golakoti, T.19
Fritzer-Szekeres, M.20
Szekeres, T.21
Krupitza, G.22
more..
-
121
-
-
13844281685
-
Bioavailability and bioefficacy of polyphenols in humans. I. Review of 97 bioavailability studies
-
Manach C, Williamson G, Morand C, Scalbert A, and Ré-mésy C. Bioavailability and bioefficacy of polyphenols in humans. I. Review of 97 bioavailability studies. Am J Clin Nutr 81 (1 Suppl): 230S-242S, 2005.
-
(2005)
Am J Clin Nutr
, vol.81
, Issue.1 SUPPL.
-
-
Manach, C.1
Williamson, G.2
Morand, C.3
Scalbert, A.4
Ré-mésy, C.5
-
122
-
-
33644660982
-
Green tea catechins as brain-permeable, natural iron chelators- antioxidants for the treatment of neurodegenerative disorders
-
Mandel S, Amit T, Reznichenko L, Weinreb O, and Youdim MB. Green tea catechins as brain-permeable, natural iron chelators-antioxidants for the treatment of neurodegenerative disorders. Mol Nutr Food Res 50: 229-234, 2006.
-
(2006)
Mol Nutr Food Res
, vol.50
, pp. 229-234
-
-
Mandel, S.1
Amit, T.2
Reznichenko, L.3
Weinreb, O.4
Youdim, M.B.5
-
123
-
-
27844497059
-
Resveratrol promotes clearance of Alzheimer's disease amyloid-beta peptides
-
Marambaud P, Zhao H, and Davies P. Resveratrol promotes clearance of Alzheimer's disease amyloid-beta peptides. J Biol Chem 280: 37377-37382, 2005.
-
(2005)
J Biol Chem
, vol.280
, pp. 37377-37382
-
-
Marambaud, P.1
Zhao, H.2
Davies, P.3
-
124
-
-
73449124480
-
Mitochondrial glutathione, a key survival antioxidant
-
Maŕ M, Morales A, Colell A, Garća-Ruiz C, and Fernández-Checa JC. Mitochondrial glutathione, a key survival antioxidant. Antioxid Redox Signal 11: 2685-2700, 2009.
-
(2009)
Antioxid Redox Signal
, vol.11
, pp. 2685-2700
-
-
Maŕ, M.1
Morales, A.2
Colell, A.3
Garća-Ruiz, C.4
Fernández-Checa, J.C.5
-
125
-
-
0036326071
-
Stimulatory effect of vitamin C on autophagy in glial cells
-
Martin A, Joseph JA, and Cuervo AM. Stimulatory effect of vitamin C on autophagy in glial cells. J Neurochem 82: 538-549, 2002.
-
(2002)
J Neurochem
, vol.82
, pp. 538-549
-
-
Martin, A.1
Joseph, J.A.2
Cuervo, A.M.3
-
126
-
-
66449087483
-
Assembly of the mitochondrial apoptosis-induced channel, MAC
-
Martinez-Caballero S, Dejean LM, Kinnally MS, Oh KJ, Mannella CA, and Kinnally KW. Assembly of the mitochondrial apoptosis-induced channel, MAC. J Biol Chem 284: 12235-12245, 2009.
-
(2009)
J Biol Chem
, vol.284
, pp. 12235-12245
-
-
Martinez-Caballero, S.1
Dejean, L.M.2
Kinnally, M.S.3
Oh, K.J.4
Mannella, C.A.5
Kinnally, K.W.6
-
127
-
-
65549136627
-
Sarcopenia of aging: Underlying cellular mechanisms and protection by calorie restriction
-
Marzetti E, Lees HA, Wohlgemuth SE, and Leeuwenburgh C. Sarcopenia of aging: underlying cellular mechanisms and protection by calorie restriction. Biofactors 35: 28-35, 2009.
-
(2009)
Biofactors
, vol.35
, pp. 28-35
-
-
Marzetti, E.1
Lees, H.A.2
Wohlgemuth, S.E.3
Leeuwenburgh, C.4
-
128
-
-
77953812468
-
The pivotal roles of mitochondria in cancer: Warburg and beyond and encouraging prospects for effective therapies
-
Mathupala SP, Ko YH, and Pedersen PL. The pivotal roles of mitochondria in cancer: warburg and beyond and encouraging prospects for effective therapies. Biochim Biophys Acta 1797: 1225-1230, 2010.
-
(2010)
Biochim Biophys Acta
, vol.1797
, pp. 1225-1230
-
-
Mathupala, S.P.1
Ko, Y.H.2
Pedersen, P.L.3
-
129
-
-
37749037128
-
Dietary factors, hormesis and health
-
Mattson MP. Dietary factors, hormesis and health. Ageing Res Rev 7: 43-48, 2008.
-
(2008)
Ageing Res Rev
, vol.7
, pp. 43-48
-
-
Mattson, M.P.1
-
130
-
-
0036834556
-
Discovery of cancer preventive agents from natural products: From plants to prevention
-
Mehta RG and Pezzuto JM. Discovery of cancer preventive agents from natural products: from plants to prevention. Curr Oncol Rep 4: 478-486, 2002.
-
(2002)
Curr Oncol Rep
, vol.4
, pp. 478-486
-
-
Mehta, R.G.1
Pezzuto, J.M.2
-
131
-
-
53049103850
-
Dichloroacetate (DCA) as a potential metabolic-targeting therapy for cancer
-
Michelakis ED, Webster L, and Mackey JR. Dichloroacetate (DCA) as a potential metabolic-targeting therapy for cancer. Br J Cancer 99: 989-994, 2008.
-
(2008)
Br J Cancer
, vol.99
, pp. 989-994
-
-
Michelakis, E.D.1
Webster, L.2
Mackey, J.R.3
-
132
-
-
77949801029
-
Mitofusin 2 is necessary for transport of axonal mitochondria and interacts with the Miro/Milton complex
-
Misko A, Jiang S, Wegorzewska I, Milbrandt J, and Baloh RH. Mitofusin 2 is necessary for transport of axonal mitochondria and interacts with the Miro/Milton complex. J Neurosci 30: 4232-4240, 2010.
-
(2010)
J Neurosci
, vol.30
, pp. 4232-4240
-
-
Misko, A.1
Jiang, S.2
Wegorzewska, I.3
Milbrandt, J.4
Baloh, R.H.5
-
133
-
-
9444255779
-
Direct activation of the mitochondrial calcium uniporter by natural plant flavonoids
-
Montero M, Lobatón CD, Hernández-Sanmiguel E, Santodomingo J, Vay L, Moreno A, and Alvarez J. Direct activation of the mitochondrial calcium uniporter by natural plant flavonoids. Biochem J 384: 19-24, 2004.
-
(2004)
Biochem J
, vol.384
, pp. 19-24
-
-
Montero, M.1
Lobatón, C.D.2
Hernández-Sanmiguel, E.3
Santodomingo, J.4
Vay, L.5
Moreno, A.6
Alvarez, J.7
-
134
-
-
39149104669
-
Metabolism of resveratrol in breast cancer cell lines: Impact of sulfotransferase 1A1 expression on cell growth inhibition
-
Murias M, Miksits M, Aust S, Spatzenegger M, Thalhammer T, Szekeres T, and Jaeger W. Metabolism of resveratrol in breast cancer cell lines: impact of sulfotransferase 1A1 expression on cell growth inhibition. Cancer Lett 261: 172-182, 2008.
-
(2008)
Cancer Lett
, vol.261
, pp. 172-182
-
-
Murias, M.1
Miksits, M.2
Aust, S.3
Spatzenegger, M.4
Thalhammer, T.5
Szekeres, T.6
Jaeger, W.7
-
135
-
-
58249093939
-
How mitochondria produce reactive oxygen species
-
Murphy MP. How mitochondria produce reactive oxygen species. Biochem J 417: 1-13, 2009.
-
(2009)
Biochem J
, vol.417
, pp. 1-13
-
-
Murphy, M.P.1
-
136
-
-
23844541335
-
Green tea component, catechin, induces apoptosis of human malignant B cells via production of reactive oxygen species
-
Nakazato T, Ito K, Ikeda Y, and Kizaki M. Green tea component, catechin, induces apoptosis of human malignant B cells via production of reactive oxygen species. Clin Cancer Res 11: 6040-6049, 2005.
-
(2005)
Clin Cancer Res
, vol.11
, pp. 6040-6049
-
-
Nakazato, T.1
Ito, K.2
Ikeda, Y.3
Kizaki, M.4
-
137
-
-
0347477308
-
Natural modulators of large-conductance calcium-activated potassium channels
-
Nardi A, Calderone V, Chericoni S, and Morelli I. Natural modulators of large-conductance calcium-activated potassium channels. Planta Med 69: 885-892, 2003.
-
(2003)
Planta Med
, vol.69
, pp. 885-892
-
-
Nardi, A.1
Calderone, V.2
Chericoni, S.3
Morelli, I.4
-
138
-
-
51749092348
-
Glycogen synthase kinase-3 inactivation is not required for ischemic preconditioning or postconditioning in the mouse
-
Nishino Y, Webb IG, Davidson SM, Ahmed AI, Clark JE, Jacquet S, Shah AM, Miura T, Yellon DM, Avkiran M, and Marber MS. Glycogen synthase kinase-3 inactivation is not required for ischemic preconditioning or postconditioning in the mouse. Circ Res 103: 307-314, 2008.
-
(2008)
Circ Res
, vol.103
, pp. 307-314
-
-
Nishino, Y.1
Webb, I.G.2
Davidson, S.M.3
Ahmed, A.I.4
Clark, J.E.5
Jacquet, S.6
Shah, A.M.7
Miura, T.8
Yellon, D.M.9
Avkiran, M.10
Marber, M.S.11
-
139
-
-
77957653033
-
Overexpression of TFAM improves the mitochondrial disease phenotypes in a mouse model system
-
Nishiyama S, Shitara H, Nakada K, Ono T, Sato A, Suzuki H, Ogawa T, Masaki H, Hayashi J, and Yonekawa H. Overexpression of TFAM improves the mitochondrial disease phenotypes in a mouse model system. Biochem Biophys Res Commun 401: 26-31, 2010.
-
(2010)
Biochem Biophys Res Commun
, vol.401
, pp. 26-31
-
-
Nishiyama, S.1
Shitara, H.2
Nakada, K.3
Ono, T.4
Sato, A.5
Suzuki, H.6
Ogawa, T.7
Masaki, H.8
Hayashi, J.9
Yonekawa, H.10
-
140
-
-
56349169766
-
An increase in intracellular Ca2 + is required for the activation of mitochondrial calpain to release AIF during cell death
-
Norberg E, Gogvadze V, Ott M, Horn M, Uhlén P, Orrenius S, and Zhivotovsky B. An increase in intracellular Ca2 + is required for the activation of mitochondrial calpain to release AIF during cell death. Cell Death Differ 15: 1857-1864, 2008.
-
(2008)
Cell Death Differ
, vol.15
, pp. 1857-1864
-
-
Norberg, E.1
Gogvadze, V.2
Ott, M.3
Horn, M.4
Uhlén, P.5
Orrenius, S.6
Zhivotovsky, B.7
-
141
-
-
17844403545
-
Role of oxidative carbonylation in protein quality control and senescence
-
Nyström T. Role of oxidative carbonylation in protein quality control and senescence. EMBO J 24: 1311-1317, 2005.
-
(2005)
EMBO J
, vol.24
, pp. 1311-1317
-
-
Nyström, T.1
-
142
-
-
78650527416
-
Cell death mechanisms and their implications in toxicology
-
Orrenius S, Nicotera P, and Zhivotovsky B. Cell death mechanisms and their implications in toxicology. Toxicol Sci 119: 3-19, 2011.
-
(2011)
Toxicol Sci
, vol.119
, pp. 3-19
-
-
Orrenius, S.1
Nicotera, P.2
Zhivotovsky, B.3
-
143
-
-
77950246109
-
SRT1720 SRT2183 SRT1460 and resveratrol are not direct activators of SIRT1
-
Pacholec M, Bleasdale JE, Chrunyk B, Cunningham D, Flynn D, Garofalo RS, Griffith D, Griffor M, Loulakis P, Pabst B, Qiu X, Stockman B, Thanabal V, Varghese A, Ward J, Withka J, and Ahn K. SRT1720, SRT2183, SRT1460, and resveratrol are not direct activators of SIRT1. J Biol Chem 285: 8340-8351, 2010.
-
(2010)
J Biol Chem
, vol.285
, pp. 8340-8351
-
-
Pacholec, M.1
Bleasdale, J.E.2
Chrunyk, B.3
Cunningham, D.4
Flynn, D.5
Garofalo, R.S.6
Griffith, D.7
Griffor, M.8
Loulakis, P.9
Pabst, B.10
Qiu, X.11
Stockman, B.12
Thanabal, V.13
Varghese, A.14
Ward, J.15
Withka, J.16
Ahn, K.17
-
144
-
-
46349103594
-
A mitochondrial protein compendium elucidates complex i disease biology
-
Pagliarini DJ, Calvo SE, Chang B, Sheth SA, Vafai SB, Ong SE, Walford GA, Sugiana C, Boneh A, Chen WK, Hill DE, Vidal M, Evans JG, Thorburn DR, Carr SA, and Mootha VK. A mitochondrial protein compendium elucidates complex I disease biology. Cell 134: 112-123, 2008.
-
(2008)
Cell
, vol.134
, pp. 112-123
-
-
Pagliarini, D.J.1
Calvo, S.E.2
Chang, B.3
Sheth, S.A.4
Vafai, S.B.5
Ong, S.E.6
Walford, G.A.7
Sugiana, C.8
Boneh, A.9
Chen, W.K.10
Hill, D.E.11
Vidal, M.12
Evans, J.G.13
Thorburn, D.R.14
Carr, S.A.15
Mootha, V.K.16
-
146
-
-
77957578387
-
Inhibition of cancer cell invasion and metastasis by genistein
-
Pavese JM, Farmer RL, and Bergan RC. Inhibition of cancer cell invasion and metastasis by genistein. Cancer Metastasis Rev 29: 465-482, 2010.
-
(2010)
Cancer Metastasis Rev
, vol.29
, pp. 465-482
-
-
Pavese, J.M.1
Farmer, R.L.2
Bergan, R.C.3
-
147
-
-
57049133445
-
Protontranslocating transhydrogenase: An update of unsolved and controversial issues
-
Pedersen A, Karlsson GB, and Rydström J. Protontranslocating transhydrogenase: an update of unsolved and controversial issues. J Bioenerg Biomembr 40: 463-473, 2008.
-
(2008)
J Bioenerg Biomembr
, vol.40
, pp. 463-473
-
-
Pedersen, A.1
Karlsson, G.B.2
Rydström, J.3
-
148
-
-
34250768073
-
A cut short to death: Parl and Opa1 in the regulation of mitochondrial morphology and apoptosis
-
Pellegrini L and Scorrano L. A cut short to death: Parl and Opa1 in the regulation of mitochondrial morphology and apoptosis. Cell Death Differ 14: 1275-1284, 2007.
-
(2007)
Cell Death Differ
, vol.14
, pp. 1275-1284
-
-
Pellegrini, L.1
Scorrano, L.2
-
149
-
-
69949091182
-
Is the oxidative stress theory of aging dead?
-
Pérez VI, Bokov A, Van Remmen H, Mele J, Ran Q, Ikeno Y, and Richardson A. Is the oxidative stress theory of aging dead? Biochim Biophys Acta 1790: 1005-1014, 2009.
-
(2009)
Biochim Biophys Acta
, vol.1790
, pp. 1005-1014
-
-
Pérez, V.I.1
Bokov, A.2
Van Remmen, H.3
Mele, J.4
Ran, Q.5
Ikeno, Y.6
Richardson, A.7
-
150
-
-
59049086591
-
The overexpression of major antioxidant enzymes does not extend the lifespan of mice
-
Pérez VI, Van Remmen H, Bokov A, Epstein CJ, Vijg J, and Richardson A. The overexpression of major antioxidant enzymes does not extend the lifespan of mice. Aging Cell 8: 73-75, 2009.
-
(2009)
Aging Cell
, vol.8
, pp. 73-75
-
-
Pérez, V.I.1
Van Remmen, H.2
Bokov, A.3
Epstein, C.J.4
Vijg, J.5
Richardson, A.6
-
151
-
-
63149091751
-
A review of the antioxidant mechanisms of polyphenol compounds related to iron binding
-
Perron NR and Brumaghim JL. A review of the antioxidant mechanisms of polyphenol compounds related to iron binding. Cell Biochem Biophys 53: 75-100, 2009.
-
(2009)
Cell Biochem Biophys
, vol.53
, pp. 75-100
-
-
Perron, N.R.1
Brumaghim, J.L.2
-
152
-
-
78851472160
-
Resveratrol in cardiovascular health and disease
-
Petrovsky G, Gurusamy N, and Das K. Resveratrol in cardiovascular health and disease. Ann NY Acad Sci 1215: 22-33, 2011.
-
(2011)
Ann NY Acad Sci
, vol.1215
, pp. 22-33
-
-
Petrovsky, G.1
Gurusamy, N.2
Das, K.3
-
153
-
-
79151479117
-
The intestinal microbiome: A separate organ inside the body with the metabolic potential to influence the bioactivity of botanicals
-
Possemiers S, Bolca S, Verstraete W, and Heyrick A. The intestinal microbiome: a separate organ inside the body with the metabolic potential to influence the bioactivity of botanicals. Fitoterapia 82: 53-66, 2011.
-
(2011)
Fitoterapia
, vol.82
, pp. 53-66
-
-
Possemiers, S.1
Bolca, S.2
Verstraete, W.3
Heyrick, A.4
-
154
-
-
77955081026
-
Targeting inflammatory pathways by flavonoids for prevention and treatment of cancer
-
Prasad S, Phromnoi K, Yadav VR, Chaturvedi MM, and Aggarwal BB. Targeting inflammatory pathways by flavonoids for prevention and treatment of cancer. Planta Med 76: 1044-1063, 2010.
-
(2010)
Planta Med
, vol.76
, pp. 1044-1063
-
-
Prasad, S.1
Phromnoi, K.2
Yadav, V.R.3
Chaturvedi, M.M.4
Aggarwal, B.B.5
-
155
-
-
34447092454
-
Quercetin mediates preferential degradation of oncogenic Ras and causes autophagy in Ha-RAS-transformed human colon cells
-
Psahoulia FH, Moumtzi S, Roberts ML, Sasazuki T, Shirasawa S, and Pintzas A. Quercetin mediates preferential degradation of oncogenic Ras and causes autophagy in Ha-RAS-transformed human colon cells. Carcinogenesis 28: 1021-1031, 2007.
-
(2007)
Carcinogenesis
, vol.28
, pp. 1021-1031
-
-
Psahoulia, F.H.1
Moumtzi, S.2
Roberts, M.L.3
Sasazuki, T.4
Shirasawa, S.5
Pintzas, A.6
-
156
-
-
74749095725
-
Pretreatment with a combination of quercetin and alpha-tocopherol ameliorates adenosine triphosphatases and lysosomal enzymes in myocardial infarcted rats
-
Punithavathi VR and Prince PS. Pretreatment with a combination of quercetin and alpha-tocopherol ameliorates adenosine triphosphatases and lysosomal enzymes in myocardial infarcted rats. Life Sci 86: 178-184, 2010.
-
(2010)
Life Sci
, vol.86
, pp. 178-184
-
-
Punithavathi, V.R.1
Prince, P.S.2
-
158
-
-
65549144609
-
Mitochondria as targets for cancer therapy
-
Ralph SJ and Neuzil J. Mitochondria as targets for cancer therapy. Mol Nutr Food Res 53: 9-28, 2009.
-
(2009)
Mol Nutr Food Res
, vol.53
, pp. 9-28
-
-
Ralph, S.J.1
Neuzil, J.2
-
159
-
-
77649183649
-
Bioenergetic pathways in tumor mitochondria as targets for cancer therapy and the importance of the ROS-induced apoptotic trigger
-
Ralph SJ, Rodŕguez-Enŕquez S, Neuzil J, and Moreno-Sánchez R. Bioenergetic pathways in tumor mitochondria as targets for cancer therapy and the importance of the ROS-induced apoptotic trigger. Mol Aspects Med 31: 29-59, 2010.
-
(2010)
Mol Aspects Med
, vol.31
, pp. 29-59
-
-
Ralph, S.J.1
Rodŕguez-Enŕquez, S.2
Neuzil, J.3
Moreno-Sánchez, R.4
-
160
-
-
77951432631
-
The causes of cancer revisited: "Mitochondrial malignancy" and ROS-induced oncogenic transformation-why mitochondria are targets for cancer therapy
-
Ralph SJ, Rodŕguez-Enŕquez S, Neuzil J, Saavedra E, and Moreno-Sánchez R. The causes of cancer revisited: "mitochondrial malignancy" and ROS-induced oncogenic transformation-why mitochondria are targets for cancer therapy. Mol Aspects Med 31: 145-170, 2010.
-
(2010)
Mol Aspects Med
, vol.31
, pp. 145-170
-
-
Ralph, S.J.1
Rodŕguez-Enŕquez, S.2
Neuzil, J.3
Saavedra, E.4
Moreno-Sánchez, R.5
-
161
-
-
42449100009
-
Isoflavones promote mitochondrial biogenesis
-
Rasbach KA and Schnellmann RG. Isoflavones promote mitochondrial biogenesis. J Pharmacol Exp Ther 325: 536-543, 2008.
-
(2008)
J Pharmacol Exp Ther
, vol.325
, pp. 536-543
-
-
Rasbach, K.A.1
Schnellmann, R.G.2
-
162
-
-
76249084726
-
Activation of mitochondrial ERK protects cancer cells from death through inhibition of the permeability transition
-
Rasola A, Sciacovelli M, Chiara F, Pantic B, Brusilow WS, and Bernardi P. Activation of mitochondrial ERK protects cancer cells from death through inhibition of the permeability transition. Proc Natl Acad Sci USA 107: 726-731, 2010.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 726-731
-
-
Rasola, A.1
Sciacovelli, M.2
Chiara, F.3
Pantic, B.4
Brusilow, W.S.5
Bernardi, P.6
-
163
-
-
77952671613
-
Signal transduction to the permeability transition pore
-
Rasola A, Sciacovelli M, Pantic B, and Bernardi P. Signal transduction to the permeability transition pore. FEBS Lett 584: 1989-1996, 2010.
-
(2010)
FEBS Lett
, vol.584
, pp. 1989-1996
-
-
Rasola, A.1
Sciacovelli, M.2
Pantic, B.3
Bernardi, P.4
-
164
-
-
47349099404
-
Resveratrol and ischemic preconditioning in the brain
-
Raval AP, Lin HW, Dave KR, Defazio RA, Della Morte D, Kim EJ, and Perez-Pinzon MA. Resveratrol and ischemic preconditioning in the brain. Curr Med Chem 15: 1545-1551, 2008.
-
(2008)
Curr Med Chem
, vol.15
, pp. 1545-1551
-
-
Raval, A.P.1
Lin, H.W.2
Dave, K.R.3
Defazio, R.A.4
Della Morte, D.5
Kim, E.J.6
Perez-Pinzon, M.A.7
-
165
-
-
78149475088
-
Regulation of Mammalian autophagy in physiology and pathophysiology
-
Ravikumar B, Sarkar S, Davies JE, Futter M, Garcia-Arencibia M, Green-Thompson ZW, Jimenez-Sanchez M, Korolchuk VI, Lichtenberg M, Luo S, Massey DC, Menzies FM, Moreau K, Narayanan U, Renna M, Siddiqi FH, Underwood BR, Winslow AR, and Rubinsztein DC. Regulation of Mammalian autophagy in physiology and pathophysiology. Physiol Rev 90: 1383-1435, 2010.
-
(2010)
Physiol Rev
, vol.90
, pp. 1383-1435
-
-
Ravikumar, B.1
Sarkar, S.2
Davies, J.E.3
Futter, M.4
Garcia-Arencibia, M.5
Green-Thompson, Z.W.6
Jimenez-Sanchez, M.7
Korolchuk, V.I.8
Lichtenberg, M.9
Luo, S.10
Massey, D.C.11
Menzies, F.M.12
Moreau, K.13
Narayanan, U.14
Renna, M.15
Siddiqi, F.H.16
Underwood, B.R.17
Winslow, A.R.18
Rubinsztein, D.C.19
-
166
-
-
78851468921
-
Neuroprotective properties of resveratrol and derivatives
-
Richard T, Pawlus AD, Iglésias ML, Pedrot E, Waffo-Teguo P, Mérillon JM, and Monti JP. Neuroprotective properties of resveratrol and derivatives. Ann NY Acad Sci 1215: 103-108, 2011.
-
(2011)
Ann NY Acad Sci
, vol.1215
, pp. 103-108
-
-
Richard, T.1
Pawlus, A.D.2
Iglésias, M.L.3
Pedrot, E.4
Waffo-Teguo, P.5
Mérillon, J.M.6
Monti, J.P.7
-
167
-
-
78650869592
-
Mitochondrial ROS generation and its regulation: Mechanisms involved in H2O2 signaling
-
Rigoulet M, Youboue ED, and Devin A. Mitochondrial ROS generation and its regulation: mechanisms involved in H2O2 signaling. Antioxid Redox Signal 14: 459-468, 2011.
-
(2011)
Antioxid Redox Signal
, vol.14
, pp. 459-468
-
-
Rigoulet, M.1
Youboue, E.D.2
Devin, A.3
-
168
-
-
77952548782
-
How increased oxidative stress promotes longevity and metabolic health: The concept of mitochondrial hormesis (mitohormesis)
-
Ristow M and Zarse K. How increased oxidative stress promotes longevity and metabolic health: the concept of mitochondrial hormesis (mitohormesis). Exp Gerontol 45: 410-418, 2010.
-
(2010)
Exp Gerontol
, vol.45
, pp. 410-418
-
-
Ristow, M.1
Zarse, K.2
-
169
-
-
68649115556
-
Ca2 + transfer from the ER to mitochondria: When, how and why
-
Rizzuto R, Marchi S, Bonora M, Aguiari P, Bononi A, De Stefani D, Giorgi C, Leo S, Rimessi A, Siviero R, Zecchini E, and Pinton P. Ca2 + transfer from the ER to mitochondria: when, how and why. Biochim Biophys Acta 1787: 1342-1351, 2009.
-
(2009)
Biochim Biophys Acta
, vol.1787
, pp. 1342-1351
-
-
Rizzuto, R.1
Marchi, S.2
Bonora, M.3
Aguiari, P.4
Bononi, A.5
De Stefani, D.6
Giorgi, C.7
Leo, S.8
Rimessi, A.9
Siviero, R.10
Zecchini, E.11
Pinton, P.12
-
170
-
-
46549083994
-
Dietary resveratrol administration increases MnSOD expression and activity in mouse brain
-
Robb EL, Winkelmolen L, Visanji N, Brotchie J, and Stuart JA. Dietary resveratrol administration increases MnSOD expression and activity in mouse brain. Biochem Biophys Res Commun 372: 254-259, 2008.
-
(2008)
Biochem Biophys Res Commun
, vol.372
, pp. 254-259
-
-
Robb, E.L.1
Winkelmolen, L.2
Visanji, N.3
Brotchie, J.4
Stuart, J.A.5
-
172
-
-
77952586060
-
Mitochondrial fission and remodelling contributes to muscle atrophy
-
Romanello V, Guadagnin E, Gomes L, Roder I, Sandri C, Petersen Y, Milan G, Masiero E, Del Piccolo P, Foretz M, Scorrano L, Rudolf R, and Sandri M. Mitochondrial fission and remodelling contributes to muscle atrophy. EMBO J 29: 1774-1785, 2010.
-
(2010)
EMBO J
, vol.29
, pp. 1774-1785
-
-
Romanello, V.1
Guadagnin, E.2
Gomes, L.3
Roder, I.4
Sandri, C.5
Petersen, Y.6
Milan, G.7
Masiero, E.8
Del Piccolo, P.9
Foretz, M.10
Scorrano, L.11
Rudolf, R.12
Sandri, M.13
-
173
-
-
73849084212
-
VDAC2 is required for truncated BID-induced mitochondrial apoptosis by recruiting BAK to the mitochondria
-
Roy SS, Ehrlich AM, Craigen WJ, and Hajnóczky G. VDAC2 is required for truncated BID-induced mitochondrial apoptosis by recruiting BAK to the mitochondria. EMBO Rep 10: 1341-1347, 2009.
-
(2009)
EMBO Rep
, vol.10
, pp. 1341-1347
-
-
Roy, S.S.1
Ehrlich, A.M.2
Craigen, W.J.3
Hajnóczky, G.4
-
174
-
-
79952753140
-
Endurance exercise rescues progeroid aging and induces systemic mitochondrial rejuvenation in mtDNA mutator mice
-
Safdar A, Bourgeois JM, Ogborn DI, Little JP, Hettinga BP, Akhtar M, Thompson JE, Melov S, Mocellin NJ, Kujoth GC, Prolla TA, and Tarnopolsky MA. Endurance exercise rescues progeroid aging and induces systemic mitochondrial rejuvenation in mtDNA mutator mice. Proc Natl Acad Sci USA 108: 4135-4140, 2011.
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 4135-4140
-
-
Safdar, A.1
Bourgeois, J.M.2
Ogborn, D.I.3
Little, J.P.4
Hettinga, B.P.5
Akhtar, M.6
Thompson, J.E.7
Melov, S.8
Mocellin, N.J.9
Kujoth, G.C.10
Prolla, T.A.11
Tarnopolsky, M.A.12
-
175
-
-
79957960940
-
Metabolic control of mitochondrial biogenesis through the PGC-1 family regulatory network
-
Scarpulla RC. Metabolic control of mitochondrial biogenesis through the PGC-1 family regulatory network. Biochim Biophys Acta 1813: 1269-1278, 2011.
-
(2011)
Biochim Biophys Acta
, vol.1813
, pp. 1269-1278
-
-
Scarpulla, R.C.1
-
176
-
-
78650890352
-
Regulation of autophagy by ROS: Physiology and pathology
-
Scherz-Shouval R and Elazar Z. Regulation of autophagy by ROS: physiology and pathology. Trends Biochem Sci 36: 30-38, 2011.
-
(2011)
Trends Biochem Sci
, vol.36
, pp. 30-38
-
-
Scherz-Shouval, R.1
Elazar, Z.2
-
177
-
-
77953290939
-
Therapeutic prospects for mitochondrial disease
-
Schon EA, DiMauro S, Hirano M, and Gilkerson RW. Therapeutic prospects for mitochondrial disease. Trends Mol Med 16: 268-276, 2010.
-
(2010)
Trends Mol Med
, vol.16
, pp. 268-276
-
-
Schon, E.A.1
Dimauro, S.2
Hirano, M.3
Gilkerson, R.W.4
-
178
-
-
58849166492
-
Green tea epigallocatechin 3-gallate accumulates in mitochondria and displays a selective antiapoptotic effect against inducers of mitochondrial oxidative stress in neurons
-
Schroeder EK, Kelsey NA, Doyle J, Breed E, Bouchard RJ, Loucks FA, Harbison RA, and Linseman DA. Green tea epigallocatechin 3-gallate accumulates in mitochondria and displays a selective antiapoptotic effect against inducers of mitochondrial oxidative stress in neurons. Antioxid Redox Signal 11: 469-480, 2009.
-
(2009)
Antioxid Redox Signal
, vol.11
, pp. 469-480
-
-
Schroeder, E.K.1
Kelsey, N.A.2
Doyle, J.3
Breed, E.4
Bouchard, R.J.5
Loucks, F.A.6
Harbison, R.A.7
Linseman, D.A.8
-
179
-
-
70349524664
-
Cardiolipin acts as a mitochondrial signalling platform to launch apoptosis
-
Schug ZT and Gottlieb E. Cardiolipin acts as a mitochondrial signalling platform to launch apoptosis. Biochim Biophys Acta 1788: 2022-2031, 2009.
-
(2009)
Biochim Biophys Acta
, vol.1788
, pp. 2022-2031
-
-
Schug, Z.T.1
Gottlieb, E.2
-
180
-
-
68949141833
-
Opening the doors to cytochrome c: Changes in mitochondrial shape and apoptosis
-
Scorrano L. Opening the doors to cytochrome c: changes in mitochondrial shape and apoptosis. Int J Biochem Cell Biol 41: 1875-1883, 2009.
-
(2009)
Int J Biochem Cell Biol 41
, pp. 1875-1883
-
-
Scorrano, L.1
-
182
-
-
79951901778
-
Targeting cell signaling and apoptotic pathways by dietary agents: Role in the prevention and treatment of cancer
-
Shanmugam MK, Kannaiyan R, and Sethi G. Targeting cell signaling and apoptotic pathways by dietary agents: role in the prevention and treatment of cancer. Nutr Cancer 63: 161-173, 2011.
-
(2011)
Nutr Cancer
, vol.63
, pp. 161-173
-
-
Shanmugam, M.K.1
Kannaiyan, R.2
Sethi, G.3
-
183
-
-
70349324339
-
Resveratrol protects mitochondria against oxidative stress trough AMP-activated protein kinase-mediated glycogen synthase kinase-3b inhibition downstream of poly(ADP-ribose)polymerase-LKB1 pathway
-
Shin SM, Cho IJ, and Kim SG. Resveratrol protects mitochondria against oxidative stress trough AMP-activated protein kinase-mediated glycogen synthase kinase-3b inhibition downstream of poly(ADP-ribose)polymerase-LKB1 pathway. Mol Pharmacol 76: 884-895, 2009.
-
(2009)
Mol Pharmacol
, vol.76
, pp. 884-895
-
-
Shin, S.M.1
Cho, I.J.2
Kim, S.G.3
-
184
-
-
77952886494
-
VDAC, a multi-functional mitochondrial protein regulating cell life and death
-
Shoshan-Barmatz V, De Pinto V, Zweckstetter M, Raviv Z, Keinan N, and Arbel N. VDAC, a multi-functional mitochondrial protein regulating cell life and death. Mol Aspects Med 31: 227-285, 2010.
-
(2010)
Mol Aspects Med
, vol.31
, pp. 227-285
-
-
Shoshan-Barmatz, V.1
De Pinto, V.2
Zweckstetter, M.3
Raviv, Z.4
Keinan, N.5
Arbel, N.6
-
185
-
-
77957587417
-
Phytochemicals: Cancer chemoprevention and suppression of tumor onset and metastasis
-
Shu L, Cheung KL, Khor TO, Chen C, and Kong AN. Phytochemicals: cancer chemoprevention and suppression of tumor onset and metastasis. Cancer Metastasis Rev 29: 483-502, 2010.
-
(2010)
Cancer Metastasis Rev
, vol.29
, pp. 483-502
-
-
Shu, L.1
Cheung, K.L.2
Khor, T.O.3
Chen, C.4
Kong, A.N.5
-
186
-
-
77958019137
-
Nanochemoprevention: Sustained release of bioactive food components for cancer prevention
-
Siddiqui IA, Adhami VM, Ahmad N, and Mukhtar H. Nanochemoprevention: sustained release of bioactive food components for cancer prevention. Nutr Cancer 62: 883-890, 2010.
-
(2010)
Nutr Cancer
, vol.62
, pp. 883-890
-
-
Siddiqui, I.A.1
Adhami, V.M.2
Ahmad, N.3
Mukhtar, H.4
-
187
-
-
78649636576
-
Dietary isoflavones and vascular protection: Activation of cellular antioxidant defenses by SERMs or hormesis?
-
Siow RC and Mann GE. Dietary isoflavones and vascular protection: activation of cellular antioxidant defenses by SERMs or hormesis? Mol Aspects Med 31: 468-477, 2010.
-
(2010)
Mol Aspects Med
, vol.31
, pp. 468-477
-
-
Siow, R.C.1
Mann, G.E.2
-
188
-
-
67349283471
-
An attempt to prevent senescence: A mitochondrial approach
-
Skulachev VP, Anisimov VN, Antonenko YN, Bakeeva LE, Chernyak BV, Erichev VP, Filenko OF, Kalinina NI, Kapelko VI, Kolosova NG, Kopnin BP, Korshunova GA, Lichinitser MR, Obukhova LA, Pasyukova EG, Pisarenko OI, Roginsky VA, Ruuge EK, Senin II, Severina II, Skulachev MV, Spivak IM, Tashlitsky VN, Tkachuk VA, Vyssokikh MY, Yaguzhinsky LS, and Zorov DB. An attempt to prevent senescence: a mitochondrial approach. Biochim Biophys Acta 1787: 437-461, 2009.
-
(2009)
Biochim Biophys Acta
, vol.1787
, pp. 437-461
-
-
Skulachev, V.P.1
Anisimov, V.N.2
Antonenko, Y.N.3
Bakeeva, L.E.4
Chernyak, B.V.5
Erichev, V.P.6
Filenko, O.F.7
Kalinina, N.I.8
Kapelko, V.I.9
Kolosova, N.G.10
Kopnin, B.P.11
Korshunova, G.A.12
Lichinitser, M.R.13
Obukhova, L.A.14
Pasyukova, E.G.15
Pisarenko, O.I.16
Roginsky, V.A.17
Ruuge, E.K.18
Senin, I.I.19
Severina, I.I.20
Skulachev, M.V.21
Spivak, I.M.22
Tashlitsky, V.N.23
Tkachuk, V.A.24
Vyssokikh, M.Y.25
Yaguzhinsky, L.S.26
Zorov, D.B.27
more..
-
189
-
-
18544372447
-
Phosphorylation of p66Shc and forkhead proteins mediates Abeta toxicity
-
Smith WW, Norton DD, Gorospe M, Jiang H, Nemoto S, Holbrook NJ, Finkel T, and Kusiak JW. Phosphorylation of p66Shc and forkhead proteins mediates Abeta toxicity. J Cell Biol 169: 331-339, 2005.
-
(2005)
J Cell Biol
, vol.169
, pp. 331-339
-
-
Smith, W.W.1
Norton, D.D.2
Gorospe, M.3
Jiang, H.4
Nemoto, S.5
Holbrook, N.J.6
Finkel, T.7
Kusiak, J.W.8
-
190
-
-
77952310273
-
Polyphenol (-)-epigallocatechin gallate during ischemia limits infarct size via mitochondrial K(ATP) channel activation in isolated rat hearts
-
Song DK, Jang Y, Kim JH, Chun KJ, Lee D, and Xu Z. Polyphenol (-)-epigallocatechin gallate during ischemia limits infarct size via mitochondrial K(ATP) channel activation in isolated rat hearts. J Korean Med Sci 25: 380-386, 2010.
-
(2010)
J Korean Med Sci
, vol.25
, pp. 380-386
-
-
Song, D.K.1
Jang, Y.2
Kim, J.H.3
Chun, K.J.4
Lee, D.5
Xu, Z.6
-
191
-
-
77955355798
-
Fisetin induces autophagic cell death through suppression of mTOR signaling pathway in prostate cancer cells
-
Suh Y, Afaq F, Khan N, Johnson JJ, Khusro FH, and Mukhtar H. Fisetin induces autophagic cell death through suppression of mTOR signaling pathway in prostate cancer cells. Carcinogenesis 31: 1424-1433, 2010.
-
(2010)
Carcinogenesis
, vol.31
, pp. 1424-1433
-
-
Suh, Y.1
Afaq, F.2
Khan, N.3
Johnson, J.J.4
Khusro, F.H.5
Mukhtar, H.6
-
192
-
-
77955088481
-
Resveratrol as a therapeutic agent for neurodegenerative diseases
-
Sun AY, Wang Q, Simonyi A, and Sun GY. Resveratrol as a therapeutic agent for neurodegenerative diseases. Mol Neurobiol 41: 375-383, 2010.
-
(2010)
Mol Neurobiol
, vol.41
, pp. 375-383
-
-
Sun, A.Y.1
Wang, Q.2
Simonyi, A.3
Sun, G.Y.4
-
193
-
-
4944222095
-
Drp-1-dependent division of the mitochondrial network blocks intraorganellar Ca2 + waves and protects against Ca2 +-mediated apoptosis
-
Szabadkai G, Simoni AM, Chami M, Wieckowski MR, Youle RJ, and Rizzuto R. Drp-1-dependent division of the mitochondrial network blocks intraorganellar Ca2 + waves and protects against Ca2 +-mediated apoptosis. Mol Cell 16: 59-68, 2004.
-
(2004)
Mol Cell
, vol.16
, pp. 59-68
-
-
Szabadkai, G.1
Simoni, A.M.2
Chami, M.3
Wieckowski, M.R.4
Youle, R.J.5
Rizzuto, R.6
-
194
-
-
51149089082
-
And Gulbins e Mitochondrial potassium channel Kv1.3 mediates Bax-induced apoptosis in lymphocytes
-
Szabó I, Bock J, Grassmé H, Soddemann M, Wilker B, Lang F, Zoratti M, and Gulbins E Mitochondrial potassium channel Kv1.3 mediates Bax-induced apoptosis in lymphocytes. Proc Natl Acad Sci USA 105: 14861-14866, 2008.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 14861-14866
-
-
Szabó, I.1
Bock, J.2
Grassmé, H.3
Soddemann, M.4
Wilker, B.5
Lang, F.6
Zoratti, M.7
-
195
-
-
79951681014
-
Single-point mutations of a lysine residue change function of Bax and Bcl-x(L) expressed in Bax-and Bak-less mouse embryonic fibroblasts: Novel insights into the molecular mechanisms of Bax-induced apoptosis
-
Szabò I, Soddemann M, Leanza L, Zoratti M, and Gulbins E. Single-point mutations of a lysine residue change function of Bax and Bcl-x(L) expressed in Bax-and Bak-less mouse embryonic fibroblasts: novel insights into the molecular mechanisms of Bax-induced apoptosis. Cell Death Differ 18: 427-438, 2011.
-
(2011)
Cell Death Differ
, vol.18
, pp. 427-438
-
-
Szabò, I.1
Soddemann, M.2
Leanza, L.3
Zoratti, M.4
Gulbins, E.5
-
197
-
-
78851469053
-
Anti-diabetic effects of resveratrol
-
Szkudelski T and Szkudelska K. Anti-diabetic effects of resveratrol. Ann NY Acad Sci 1215: 34-39, 2011.
-
(2011)
Ann NY Acad Sci
, vol.1215
, pp. 34-39
-
-
Szkudelski, T.1
Szkudelska, K.2
-
198
-
-
79960021791
-
Apoptosis signaling kinases: From stress response to health outcome
-
Epub ahead of print]; DOI 10.1089/ars.2010.3392
-
Takeda K, Naguro I, Nishitoh H, Matsuzawa A, and Ichijo H. Apoptosis signaling kinases: from stress response to health outcome. Antioxid Redox Signal 2011, [Epub ahead of print]; DOI 10.1089/ars.2010.3392.
-
(2011)
Antioxid Redox Signal
-
-
Takeda, K.1
Naguro, I.2
Nishitoh, H.3
Matsuzawa, A.4
Ichijo, H.5
-
199
-
-
84887212354
-
Heterozygous mutation of Opa1 in Drosophila shortens lifespan mediated through increased reactive oxygen species production
-
Tang S, Le PK, Tse S, Wallace DC, and Huang T. Heterozygous mutation of Opa1 in Drosophila shortens lifespan mediated through increased reactive oxygen species production. PLoS One 4: e4492, 2009.
-
(2009)
PLoS One
, vol.4
-
-
Tang, S.1
Le Tse, P.K.S.2
Wallace, D.C.3
Huang, T.4
-
201
-
-
33745617384
-
Mitochondrial DNA and ageing
-
Trifunovic A. Mitochondrial DNA and ageing. Biochim Biophys Acta 1757: 611-617, 2006.
-
(2006)
Biochim Biophys Acta
, vol.1757
, pp. 611-617
-
-
Trifunovic, A.1
-
202
-
-
29144458899
-
Somatic mtDNA mutations cause aging phenotypes without affecting reactive oxygen species production
-
Trifunovic A, Hansson A, Wredenberg A, Rovio AT, Dufour E, Khvorostov I, Spelbrink JN, Wibom R, Jacobs HT, and Larsson NG. Somatic mtDNA mutations cause aging phenotypes without affecting reactive oxygen species production. Proc Natl Acad Sci USA 102: 17993-17998, 2005.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 17993-17998
-
-
Trifunovic, A.1
Hansson, A.2
Wredenberg, A.3
Rovio, A.T.4
Dufour, E.5
Khvorostov, I.6
Spelbrink, J.N.7
Wibom, R.8
Jacobs, H.T.9
Larsson, N.G.10
-
203
-
-
38349108752
-
Mitochondrial dysfunction as a cause of ageing
-
Trifunovic A and Larsson NG. Mitochondrial dysfunction as a cause of ageing. J Intern Med 263: 167-178, 2008.
-
(2008)
J Intern Med
, vol.263
, pp. 167-178
-
-
Trifunovic, A.1
Larsson, N.G.2
-
204
-
-
2642580016
-
Premature ageing in mice expressing defective mitochondrial DNA polymerase
-
Trifunovic A, Wredenberg A, Falkenberg M, Spelbrink JN, Rovio AT, Bruder CE, Bohlooly-Y M, Gidlöf S, Oldfors A, Wibom R, Törnell J, Jacobs HT, and Larsson NG. Premature ageing in mice expressing defective mitochondrial DNA polymerase. Nature 429: 417-423, 2004.
-
(2004)
Nature
, vol.429
, pp. 417-423
-
-
Trifunovic, A.1
Wredenberg, A.2
Falkenberg, M.3
Spelbrink, J.N.4
Rovio, A.T.5
Bruder, C.E.6
Bohlooly-Y, M.7
Gidlöf, S.8
Oldfors, A.9
Wibom, R.10
Törnell, J.11
Jacobs, H.T.12
Larsson, N.G.13
-
205
-
-
77953953488
-
P66Shc signals to age
-
Trinei M, Berniakovich I, Beltrami E, Migliaccio E, Fassina A, Pelicci P, and Giorgio M. P66Shc signals to age. Aging (Albany NY) 1: 503-510, 2009.
-
(2009)
Aging (Albany NY)
, vol.1
, pp. 503-510
-
-
Trinei, M.1
Berniakovich, I.2
Beltrami, E.3
Migliaccio, E.4
Fassina, A.5
Pelicci, P.6
Giorgio, M.7
-
206
-
-
73249151195
-
Mitochondrial DNA mutations and human disease
-
Tuppen HA, Blakely EL, Turnbull DM, and Taylor RW. Mitochondrial DNA mutations and human disease. Biochim Biophys Acta 1797: 113-128, 2010.
-
(2010)
Biochim Biophys Acta
, vol.1797
, pp. 113-128
-
-
Tuppen, H.A.1
Blakely, E.L.2
Turnbull, D.M.3
Taylor, R.W.4
-
207
-
-
63049118830
-
Antioxidant and pro-oxidant capacities of ITCs
-
Valgimigli L and Iori R. Antioxidant and pro-oxidant capacities of ITCs. Environ Mol Mutagen 50: 222-237, 2009.
-
(2009)
Environ Mol Mutagen
, vol.50
, pp. 222-237
-
-
Valgimigli, L.1
Iori, R.2
-
208
-
-
77957105977
-
Molecular mechanisms of necroptosis: An ordered cellular explosion
-
Vandenabeele P, Galluzzi L, Vanden Berghe T, and Kroemer G. Molecular mechanisms of necroptosis: an ordered cellular explosion. Nat Rev Mol Cell Biol 11: 700-714, 2010.
-
(2010)
Nat Rev Mol Cell Biol
, vol.11
, pp. 700-714
-
-
Vandenabeele, P.1
Galluzzi, L.2
Vanden Berghe, T.3
Kroemer, G.4
-
209
-
-
77952236200
-
Necroptosis, necrosis and secondary necrosis converge on similar cellular disintegration features
-
Vanden Berghe T, Vanlangenakker N, Parthoens E, Deckers W, Devos M, Festjens N, Guerin CJ, Brunk UT, Declercq W, and Vandenabeele P. Necroptosis, necrosis and secondary necrosis converge on similar cellular disintegration features. Cell Death Differ 17: 922-930, 2010.
-
(2010)
Cell Death Differ
, vol.17
, pp. 922-930
-
-
Vanden Berghe, T.1
Vanlangenakker, N.2
Parthoens, E.3
Deckers, W.4
Devos, M.5
Festjens, N.6
Guerin, C.J.7
Brunk, U.T.8
Declercq, W.9
Vandenabeele, P.10
-
210
-
-
12144288373
-
Life-long reduction in MnSOD activity results in increased DNA damage and higher incidence of cancer but does not accelerate aging
-
Van Remmen H, Ikeno Y, Hamilton M, Pahlavani M, Wolf N, Thorpe SR, Alderson NL, Baynes JW, Epstein CJ, Huang TT, Nelson J, Strong R, and Richardson A. Life-long reduction in MnSOD activity results in increased DNA damage and higher incidence of cancer but does not accelerate aging. Physiol Genomics 16: 29-37, 2003.
-
(2003)
Physiol Genomics
, vol.16
, pp. 29-37
-
-
Van Remmen, H.1
Ikeno, Y.2
Hamilton, M.3
Pahlavani, M.4
Wolf, N.5
Thorpe, S.R.6
Alderson, N.L.7
Baynes, J.W.8
Epstein, C.J.9
Huang, T.T.10
Nelson, J.11
Strong, R.12
Richardson, A.13
-
211
-
-
77950910067
-
Mechanisms associated with mitochondrial-generated reactive oxygen species in cancer
-
Verschoor ML, Wilson LA, and Singh G. Mechanisms associated with mitochondrial-generated reactive oxygen species in cancer. Can J Physiol Pharmacol 88: 204-219, 2010.
-
(2010)
Can J Physiol Pharmacol
, vol.88
, pp. 204-219
-
-
Verschoor, M.L.1
Wilson, L.A.2
Singh, G.3
-
212
-
-
71549134294
-
Mitochondrial biogenesis in exercise and ageing
-
Viña J, Gomez-Cabrera MC, Borras C, Froio T, Sanchis-Gomar F, Martinez-Bello VE, and Pallardo FV. Mitochondrial biogenesis in exercise and ageing. Adv Drug Deliv Rev 61: 1369-1374, 2009.
-
(2009)
Adv Drug Deliv Rev
, vol.61
, pp. 1369-1374
-
-
Viña, J.1
Gomez-Cabrera, M.C.2
Borras, C.3
Froio, T.4
Sanchis-Gomar, F.5
Martinez-Bello, V.E.6
Pallardo, F.V.7
-
213
-
-
77950575506
-
AMP-activated protein kinase signalling activation by resveratrol modulates amyloid-beta peptide metabolism
-
Vingtdeux V, Giliberto L, Zhao H, Chandakkar P, Wu Q, Simon JE, Janle EM, Lobo J, Ferruzzi MG, Davies P, and Marambaud P. AMP-activated protein kinase signalling activation by resveratrol modulates amyloid-beta peptide metabolism. J Biol Chem 285: 9100-9113, 2010.
-
(2010)
J Biol Chem
, vol.285
, pp. 9100-9113
-
-
Vingtdeux, V.1
Giliberto, L.2
Zhao, H.3
Chandakkar, P.4
Wu, Q.5
Simon, J.E.6
Janle, E.M.7
Lobo, J.8
Ferruzzi, M.G.9
Davies, P.10
Marambaud, P.11
-
215
-
-
0034956656
-
Mouse models for mitochondrial disease
-
Wallace DC. Mouse models for mitochondrial disease. Am J Med Genet 106: 71-93, 2001.
-
(2001)
Am J Med Genet
, vol.106
, pp. 71-93
-
-
Wallace, D.C.1
-
216
-
-
77953507107
-
Mitochondrial DNA mutations in disease and aging
-
Wallace DC. Mitochondrial DNA mutations in disease and aging. Environ Mol Mutagen 51: 440-450, 2010.
-
(2010)
Environ Mol Mutagen
, vol.51
, pp. 440-450
-
-
Wallace, D.C.1
-
218
-
-
1642528478
-
Absorption and metabolism of flavonoids
-
Walle T. Absorption and metabolism of flavonoids. Free Radic Biol Med 36: 829-837, 2004.
-
(2004)
Free Radic Biol Med
, vol.36
, pp. 829-837
-
-
Walle, T.1
-
219
-
-
78851469101
-
Bioavailability of resveratrol
-
Walle T. Bioavailability of resveratrol. Ann NY Acad Sci 1215: 9-15, 2011.
-
(2011)
Ann NY Acad Sci
, vol.1215
, pp. 9-15
-
-
Walle, T.1
-
220
-
-
73349091842
-
The role of mitochondria in apoptosis
-
Wang C and Youle RJ. The role of mitochondria in apoptosis. Annu Rev Genet 43: 95-118, 2009.
-
(2009)
Annu Rev Genet
, vol.43
, pp. 95-118
-
-
Wang, C.1
Youle, R.J.2
-
221
-
-
58149105356
-
Cancer cell killing via ROS: To increase or decrease, that is the question
-
Wang J and Yi J. Cancer cell killing via ROS: to increase or decrease, that is the question. Cancer Biol Ther 7: 1875-1884, 2008.
-
(2008)
Cancer Biol Ther
, vol.7
, pp. 1875-1884
-
-
Wang, J.1
Yi, J.2
-
222
-
-
50049118173
-
Activation of the PPAR/PGC-1a pathway prevents a bioenergetic deficit and effectively improves a mitochondrial myopathy phenotype
-
Wenz T, Diaz F, Spiegelman BM, and Moraes CT. Activation of the PPAR/PGC-1a pathway prevents a bioenergetic deficit and effectively improves a mitochondrial myopathy phenotype. Cell Metab 8: 249-256, 2008.
-
(2008)
Cell Metab
, vol.8
, pp. 249-256
-
-
Wenz, T.1
Diaz, F.2
Spiegelman, B.M.3
Moraes, C.T.4
-
223
-
-
77951220669
-
Role of autophagy in suppression of inflammation and cancer
-
White E, Karp C, Strohecker AM, Guo Y, and Mathew R. Role of autophagy in suppression of inflammation and cancer. Curr Opin Cell Biol 22: 212-217, 2010.
-
(2010)
Curr Opin Cell Biol
, vol.22
, pp. 212-217
-
-
White, E.1
Karp, C.2
Strohecker, A.M.3
Guo, Y.4
Mathew, R.5
-
224
-
-
44949196953
-
Impact of mitochondrial calcium on the coupling of metabolism to insulin secretion in the pancreatic b-cell
-
Wiederkehr A, and Wollheim CB. Impact of mitochondrial calcium on the coupling of metabolism to insulin secretion in the pancreatic b-cell. Cell Calcium 44: 64-76, 2008.
-
(2008)
Cell Calcium
, vol.44
, pp. 64-76
-
-
Wiederkehr, A.1
Wollheim, C.B.2
-
225
-
-
19044388959
-
In vitro biological properties of flavonoid conjugates found in vivo
-
Williamson G, Barron D, Shimoi K, and Terao J. In vitro biological properties of flavonoid conjugates found in vivo. Free Radic Res 39: 457-469, 2005.
-
(2005)
Free Radic Res
, vol.39
, pp. 457-469
-
-
Williamson, G.1
Barron, D.2
Shimoi, K.3
Terao, J.4
-
226
-
-
77957753126
-
A review of natural and synthetic antioxidants important for health and longevity
-
Wojcik M, Burzynska-Pedziwiatr I, and Wozniak LA. A review of natural and synthetic antioxidants important for health and longevity. Curr Med Chem 17: 3262-3288, 2010.
-
(2010)
Curr Med Chem
, vol.17
, pp. 3262-3288
-
-
Wojcik, M.1
Burzynska-Pedziwiatr, I.2
Wozniak, L.A.3
-
227
-
-
70449107252
-
Redox-directed cancer therapeutics: Molecular mechanisms and opportunities
-
Wondrak GT. Redox-directed cancer therapeutics: molecular mechanisms and opportunities. Antioxid Redox Signal 11: 3013-3069, 2009.
-
(2009)
Antioxid Redox Signal
, vol.11
, pp. 3013-3069
-
-
Wondrak, G.T.1
-
228
-
-
77954116814
-
Autophagy gone awry in neurodegenerative diseases
-
Wong E and Cuervo AM. Autophagy gone awry in neurodegenerative diseases. Nat Neurosci 13: 805-811, 2010.
-
(2010)
Nat Neurosci
, vol.13
, pp. 805-811
-
-
Wong, E.1
Cuervo, A.M.2
-
229
-
-
79952520044
-
Mitochondrial oxidative stress causes mitochondrial fragmentation via differential modulation of mitochondrial fission-fusion proteins
-
Wu S, Zhou F, Zhang Z, and Xing D. Mitochondrial oxidative stress causes mitochondrial fragmentation via differential modulation of mitochondrial fission-fusion proteins. FEBS J 278: 941-954, 2011.
-
(2011)
FEBS J
, vol.278
, pp. 941-954
-
-
Wu, S.1
Zhou, F.2
Zhang, Z.3
Xing, D.4
-
230
-
-
77955077389
-
Curcumin induces apoptosis in human non-small cell lung cancer NCI-H460 cells through ER stress and caspase cascade-and mitochondria-dependent pathways
-
Wu SH, Hang LW, Yang JS, Chen HY, Lin HY, Chiang JH, Lu CC, Yang JL, Lai TY, Ko YC, and Chung JG. Curcumin induces apoptosis in human non-small cell lung cancer NCI-H460 cells through ER stress and caspase cascade-and mitochondria-dependent pathways. Anticancer Res 30: 2125-2133, 2010.
-
(2010)
Anticancer Res
, vol.30
, pp. 2125-2133
-
-
Wu, S.H.1
Hang, L.W.2
Yang, J.S.3
Chen, H.Y.4
Lin, H.Y.5
Chiang, J.H.6
Lu, C.C.7
Yang, J.L.8
Lai, T.Y.9
Ko, Y.C.10
Chung, J.G.11
-
231
-
-
35548996805
-
A plant triterpenoid, avicin D, induces autophagy by activation of AMP-activated protein kinase
-
Xu ZX, Liang J, Haridas V, Gaikwad A, Connolly FP, Mills GB, and Gutterman JU. A plant triterpenoid, avicin D, induces autophagy by activation of AMP-activated protein kinase. Cell Death Differ 14: 1948-1957, 2007.
-
(2007)
Cell Death Differ
, vol.14
, pp. 1948-1957
-
-
Xu, Z.X.1
Liang, J.2
Haridas, V.3
Gaikwad, A.4
Connolly, F.P.5
Mills, G.B.6
Gutterman, J.U.7
-
232
-
-
70450222302
-
The role of lysosomal rupture in neuronal death
-
Yamashima T and Oikawa S. The role of lysosomal rupture in neuronal death. Prog Neurobiol 89: 343-358, 2009.
-
(2009)
Prog Neurobiol
, vol.89
, pp. 343-358
-
-
Yamashima, T.1
Oikawa, S.2
-
233
-
-
77955348897
-
A novel water-soluble gossypol derivative increases chemotherapeutic sensitivity and promotes growth inhibition in colon cancer
-
Yan F, Cao XX, Jiang HX, Zhao XL, Wang JY, Lin YH, Liu QL, Zhang C, Jiang B, and Guo F. A novel water-soluble gossypol derivative increases chemotherapeutic sensitivity and promotes growth inhibition in colon cancer. J Med Chem 53: 5502-5510, 2010.
-
(2010)
J Med Chem
, vol.53
, pp. 5502-5510
-
-
Yan, F.1
Cao, X.X.2
Jiang, H.X.3
Zhao, X.L.4
Wang, J.Y.5
Lin, Y.H.6
Liu, Q.L.7
Zhang, C.8
Jiang, B.9
Guo, F.10
-
234
-
-
77956404377
-
Eaten alive: A history of macroautophagy
-
Yang Z and Klionsky DJ. Eaten alive: a history of macroautophagy. Nat Cell Biol 12: 814-822, 2010.
-
(2010)
Nat Cell Biol
, vol.12
, pp. 814-822
-
-
Yang, Z.1
Klionsky, D.J.2
-
235
-
-
77953669993
-
Human iron-sulfur cluster assembly, cellular iron homeostasis, and disease
-
Ye H and Rouault TA. Human iron-sulfur cluster assembly, cellular iron homeostasis, and disease. Biochemistry 49: 4945-4956, 2010.
-
(2010)
Biochemistry
, vol.49
, pp. 4945-4956
-
-
Ye, H.1
Rouault, T.A.2
-
236
-
-
77954851049
-
Wnt signaling regulates mitochondrial physiology and insulin sensitivity
-
Yoon JC, Ng A, Kim BH, Bianco A, Xavier RJ, and Elledge SJ. Wnt signaling regulates mitochondrial physiology and insulin sensitivity. Genes Dev 24: 1507-1518, 2010.
-
(2010)
Genes Dev
, vol.24
, pp. 1507-1518
-
-
Yoon, J.C.1
Ng, A.2
Kim, B.H.3
Bianco, A.4
Xavier, R.J.5
Elledge, S.J.6
-
237
-
-
77957229744
-
Quercetin potentiates insulin secretion and protects INS-1 pancreatic b-cells against oxidative damage via the ERK1/2 pathway
-
Youl E, Bardy G, Magous R, Cros G, Sejalon F, Virsolvy A, Richard S, Quignard JF, Gross R, Petit P, Bataille D, and Oiry C. Quercetin potentiates insulin secretion and protects INS-1 pancreatic b-cells against oxidative damage via the ERK1/2 pathway. Br J Pharmacol 161: 799-814, 2010.
-
(2010)
Br J Pharmacol
, vol.161
, pp. 799-814
-
-
Youl, E.1
Bardy, G.2
Magous, R.3
Cros, G.4
Sejalon, F.5
Virsolvy, A.6
Richard, S.7
Quignard, J.F.8
Gross, R.9
Petit, P.10
Bataille, D.11
Oiry, C.12
-
239
-
-
77949532182
-
Curcumin prevents dopaminergic neuronal death through inhibition of the c-Jun N-terminal kinase pathway
-
Yu S, Zheng W, Xin N, Chi ZH, Wang NQ, Nie YX, Feng WY, and Wang ZY. Curcumin prevents dopaminergic neuronal death through inhibition of the c-Jun N-terminal kinase pathway. Rejuvenation Res 13: 55-64, 2010.
-
(2010)
Rejuvenation Res
, vol.13
, pp. 55-64
-
-
Yu, S.1
Zheng, W.2
Xin, N.3
Zh, C.4
Wang, N.Q.5
Nie, Y.X.6
Feng, W.Y.7
Wang, Z.Y.8
-
240
-
-
78149312278
-
A-TEA induces apoptosis of human breast cancer cells via activation of TRAIL/DR5 death receptor pathway
-
Yu W, Tiwary R, Li J, Park SK, Jia L, Xiong A, Simmons-Menchaca M, Sanders BG, and Kline K. A-TEA induces apoptosis of human breast cancer cells via activation of TRAIL/DR5 death receptor pathway. Mol Carcinog 49: 964-973, 2010.
-
(2010)
Mol Carcinog
, vol.49
, pp. 964-973
-
-
Yu, W.1
Tiwary, R.2
Li, J.3
Park, S.K.4
Jia, L.5
Xiong, A.6
Simmons-Menchaca, M.7
Sanders, B.G.8
Kline, K.9
-
241
-
-
0034667349
-
Construction of transgenic mice with tissuespecific acceleration of mitochondrial DNA mutagenesis
-
Zhang D, Mott JL, Chang SW, Denniger G, Feng Z, and Zassenhaus HP. Construction of transgenic mice with tissuespecific acceleration of mitochondrial DNA mutagenesis. Genomics 69: 151-161, 2000.
-
(2000)
Genomics
, vol.69
, pp. 151-161
-
-
Zhang, D.1
Mott, J.L.2
Chang, S.W.3
Denniger, G.4
Feng, Z.5
Zassenhaus, H.P.6
-
242
-
-
77956213267
-
Mitochondrial dysfunction in Parkinson's disease
-
Zhu J and Chu CT. Mitochondrial dysfunction in Parkinson's disease. J Alzheimers Dis 20 Suppl 2: S325-S334, 2010.
-
(2010)
J Alzheimers Dis 20 Suppl
, vol.2
-
-
Zhu, J.1
Chu, C.T.2
-
243
-
-
77958152750
-
Hydroxytyrosol protects against oxidative damage by simultaneous activation of mitochondrial biogenesis and phase II detoxifying enzyme systems in retinal pigment epithelial cells
-
Zhu L, Liu Z, Feng Z, Hao J, Shen W, Li X, Sun L, Sharman E, Wang Y, Wertz K, Weber P, Shi X, and Liu J. Hydroxytyrosol protects against oxidative damage by simultaneous activation of mitochondrial biogenesis and phase II detoxifying enzyme systems in retinal pigment epithelial cells. J Nutr Biochem 21: 1089-1098, 2010.
-
(2010)
J Nutr Biochem
, vol.21
, pp. 1089-1098
-
-
Zhu, L.1
Liu, Z.2
Feng, Z.3
Hao, J.4
Shen, W.5
Li, X.6
Sun, L.7
Sharman, E.8
Wang, Y.9
Wertz, K.10
Weber, P.11
Shi, X.12
Liu, J.13
-
244
-
-
0033065221
-
Effects of resveratrol on the rat brain respiratory chain
-
Zini R, Morin C, Bertelli A, Bertelli AA, and Tillement JP. Effects of resveratrol on the rat brain respiratory chain. Drugs Exp Clin Res 25: 87-97, 1999.
-
(1999)
Drugs Exp Clin Res
, vol.25
, pp. 87-97
-
-
Zini, R.1
Morin, C.2
Bertelli, A.3
Bertelli, A.A.4
Tillement, J.P.5
-
245
-
-
77950384477
-
Drosophila parkin requires PINK1 for mitochondrial translocation and ubiquitinates mitofusin
-
Ziviani E, Tao RN, and Whitworth AJ. Drosophila parkin requires PINK1 for mitochondrial translocation and ubiquitinates mitofusin. Proc Natl Acad Sci USA 107: 5018-5023, 2010.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 5018-5023
-
-
Ziviani, E.1
Tao, R.N.2
Whitworth, A.J.3
-
246
-
-
67349140370
-
Novel channels of the inner mitochondrial membrane
-
Zoratti M, De Marchi U, Gulbins E, and Szabò I. Novel channels of the inner mitochondrial membrane. Biochim Biophys Acta Bioenerg 1787: 351-363, 2009.
-
(2009)
Biochim Biophys Acta Bioenerg
, vol.1787
, pp. 351-363
-
-
Zoratti, M.1
De Marchi, U.2
Gulbins, E.3
Szabò, I.4
-
247
-
-
77952675154
-
Electrophysiology clarifies the megariddles of the mitochondrial permeability transition pore
-
Zoratti M, De Marchi U, Biasutto L, and Szabò I. Electrophysiology clarifies the megariddles of the mitochondrial permeability transition pore. FEBS Lett 584: 1997-2004, 2010.
-
(2010)
FEBS Lett
, vol.584
, pp. 1997-2004
-
-
Zoratti, M.1
De Marchi, U.2
Biasutto, L.3
Szabò, I.4
-
248
-
-
77955052130
-
Naringenin, a citrus flavonoid, increases muscle cell glucose uptake via AMPK
-
Zygmunt K, Faubert B, MacNeil J, and Tsiani E. Naringenin, a citrus flavonoid, increases muscle cell glucose uptake via AMPK. Biochem Biophys Res Commun 398: 178-183, 2010.
-
(2010)
Biochem Biophys Res Commun
, vol.398
, pp. 178-183
-
-
Zygmunt, K.1
Faubert, B.2
MacNeil, J.3
Tsiani, E.4
|