Proapoptotic effects of long-chain vitamin E metabolites in HepG2 cells are mediated by oxidative stress

Free Radical Biology and Medicine

Volumn 49, Issue 8, 2010, Pages 1315-1322

  Birringer, Marc ^a   Lington, Dennis ^a   Vertuani, Silvia ^b   Manfredini, Stefano ^b   Scharlau, Daniel ^a   Glei, Michael ^a   Ristow, Michael ^a,c  

^a FRIEDRICH SCHILLER UNIVERSITY JENA   (Germany)

^b UNIVERSITY OF FERRARA   (Italy)

^c GERMAN INSTITUTE OF HUMAN NUTRITION   (Germany)

Author keywords

Apoptosis; Carboxychromanol; Free radicals; HepG2 cells; ROS; Tocopherol; Vitamin E

Indexed keywords

13' CARBOXYCHROMANOL ALPHA; 13' CARBOXYCHROMANOL GAMMA; 13' HYDROXYCHROMANOL; ALPHA TOCOPHEROL DERIVATIVE; ANTIMYCIN A1; ANTINEOPLASTIC AGENT; CASPASE 3; CASPASE 9; GAMMA TOCOPHEROL; GARCINOIC ACID; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 1; PLANT EXTRACT; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CELL DEATH; CONTROLLED STUDY; FLOW CYTOMETRY; GARCINIA KOLA; HUMAN; HUMAN TISSUE; IMMUNOBLOTTING; MEDICINAL PLANT; MEMBRANE POTENTIAL; MITOCHONDRION; OXIDATIVE STRESS; PRIORITY JOURNAL;

APOPTOSIS; BENZOPYRANS; CASPASE 3; CASPASE 9; GARCINIA KOLA; HEP G2 CELLS; HEPATOCYTES; HUMANS; MEMBRANE POTENTIAL, MITOCHONDRIAL; MITOCHONDRIA, LIVER; OXIDATIVE STRESS; POLY(ADP-RIBOSE) POLYMERASES; REACTIVE OXYGEN SPECIES; SEEDS; VITAMIN E;

ANIMALIA; GARCINIA KOLA;

EID: 80052241805     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2010.07.024     Document Type: Article

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