-
1
-
-
33746066329
-
The key role of mitochondria in Alzheimer's disease
-
Moreira PI, Cardoso SM, Santos MS, Oliveira CR (2006) The key role of mitochondria in Alzheimer's disease. J. Alzheimers Dis 9, 101-110.
-
(2006)
J. Alzheimers Dis
, vol.9
, pp. 101-110
-
-
Moreira, P.I.1
Cardoso, S.M.2
Santos, M.S.3
Oliveira, C.R.4
-
2
-
-
67649687039
-
An integrative view of the role of oxidative stress, mitochondria and insulin in Alzheimer's disease
-
Moreira PI, Duarte AI, Santos MS, Rego AC, Oliveira CR (2009) An integrative view of the role of oxidative stress, mitochondria and insulin in Alzheimer's disease. J. Alzheimers Dis 16, 741-761.
-
(2009)
J. Alzheimers Dis
, vol.16
, pp. 741-761
-
-
Moreira, P.I.1
Duarte, A.I.2
Santos, M.S.3
Rego, A.C.4
Oliveira, C.R.5
-
3
-
-
0034923434
-
Ox- idative damage is the earliest event in Alzheimer disease
-
Nunomura A, Perry G, Aliev G, Hirai K, Takeda A, Bal- raj EK, Jones PK, Ghanbari H, Wataya T, Shimohama S, Chiba S, Atwood CS, Petersen RB, Smith MA (2001) Ox- idative damage is the earliest event in Alzheimer disease. J Neuropathol Exp Neurol 60, 759-767.
-
(2001)
J Neuropathol Exp Neurol
, vol.60
, pp. 759-767
-
-
Nunomura, A.1
Perry, G.2
Aliev, G.3
Hirai, K.4
Takeda, A.5
Balraj, E.K.6
Jones, P.K.7
Ghanbari, H.8
Wataya, T.9
Shimohama, S.10
Chiba, S.11
Atwood, C.S.12
Petersen, R.B.13
Smith, M.A.14
-
4
-
-
58049202374
-
Oxidative stress signaling in Alzheimer's disease
-
Su B, Wang X, Nunomura A, Moreira PI, Lee HG, Perry G, Smith MA, Zhu X (2008) Oxidative stress signaling in Alzheimer's disease. Curr Alzheimer Res 5, 525-532.
-
(2008)
Curr Alzheimer Res
, vol.5
, pp. 525-532
-
-
Su, B.1
Wang, X.2
Nunomura, A.3
Moreira, P.I.4
Lee, H.G.5
Perry, G.6
Smith, M.A.7
Zhu, X.8
-
5
-
-
71749121998
-
Mitochondrial dysfunction is atrigger of Alzheimer's disease pathophysiology
-
Moreira PI, Carvalho C, Zhu XW, Smith MA, Perry G (2010) Mitochondrial dysfunction is atrigger of Alzheimer's disease pathophysiology. Biochim Biophys Acta 1802, 2-10.
-
(2010)
Biochim Biophys Acta
, vol.1802
, pp. 2-10
-
-
Moreira, P.I.1
Carvalho, C.2
Zhu, X.W.3
Smith, M.A.4
Perry, G.5
-
6
-
-
33644953299
-
Calcium, mitochondria and oxidative stress in neuronal pathology - Novel aspects of an enduring theme
-
Chinopoulos C, Adam-Vizi V (2006) Calcium, mitochondria and oxidative stress in neuronal pathology - Novel aspects of an enduring theme. FEBSJ 273, 433-450.
-
(2006)
FEBSJ
, vol.273
, pp. 433-450
-
-
Chinopoulos, C.1
Adam-Vizi, V.2
-
7
-
-
33645290262
-
Mitochondria: A target for neuroprotective interventions in cerebral ischemia- reperfusion
-
Chtistophe M, Nicolas S (2006) Mitochondria: A target for neuroprotective interventions in cerebral ischemia- reperfusion. Curr Pharm Design 12, 739-757.
-
(2006)
Curr Pharm Design
, vol.12
, pp. 739-757
-
-
Chtistophe, M.1
Nicolas, S.2
-
8
-
-
34249104544
-
Oxidative stress and aberrant signaling in aging and cognitive decline
-
Droge W, Schipper HM (2007) Oxidative stress and aberrant signaling in aging and cognitive decline. Aging Cell 6, 361370.
-
(2007)
Aging Cell
, vol.6
, pp. 361370
-
-
Droge, W.1
Schipper, H.M.2
-
9
-
-
14644442283
-
Oxygen, oxidative stress, hypoxia, and heart failure
-
Giordano FJ (2005) Oxygen, oxidative stress, hypoxia, and heart failure. J Clin Invest 115, 500-508.
-
(2005)
J Clin Invest
, vol.115
, pp. 500-508
-
-
Giordano, F.J.1
-
10
-
-
34548451974
-
Reactive oxygen species in mitochondria- mediated cell death
-
Orrenius S (2007) Reactive oxygen species in mitochondria- mediated cell death. DrugMetab Rev 39, 443-455.
-
(2007)
DrugMetab Rev
, vol.39
, pp. 443-455
-
-
Orrenius, S.1
-
11
-
-
24144455328
-
Role of reactive oxygen species and protein kinase C in ischemic tolerance in the brain
-
Perez-Pinzon MA, Dave KR, Raval AP (2005) Role of reactive oxygen species and protein kinase C in ischemic tolerance in the brain. Antioxid Redox Signal 7, 1150-1157.
-
(2005)
Antioxid Redox Signal
, vol.7
, pp. 1150-1157
-
-
Pericak-Vance, M.A.1
Dave, K.R.2
Raval, A.P.3
-
12
-
-
0032619360
-
Role and mechanisms of secondary mitochondrial failure
-
Siesjo B, Elmer E, Janelidze S, Keep M, Kristian T, Ouyang Y, Uchino H (1999) Role and mechanisms of secondary mitochondrial failure. ActaNeurochir Suppl 73, 7-13.
-
(1999)
ActaNeurochir Suppl
, vol.73
, pp. 7-13
-
-
Siesjo, B.1
Elmer, E.2
Janelidze, S.3
Keep, M.4
Kristian, T.5
Ouyang, Y.6
Uchino, H.7
-
13
-
-
3342910554
-
Mitochondrial calcium and oxidative stress as mediators of ischemic brain injury
-
Starkov AA, Chinopoulos C, Fiskum G (2004) Mitochondrial calcium and oxidative stress as mediators of ischemic brain injury. Cell Calcium 36, 257-264.
-
(2004)
Cell Calcium
, vol.36
, pp. 257-264
-
-
Starkov, A.A.1
Chinopoulos, C.2
Fiskum, G.3
-
14
-
-
33749986298
-
Free radicals and antioxidants in normal physiological functions and human disease
-
Valko M, Leibfritz D, Moncol J, Cronin MTD, Mazur M, Telser J (2007) Free radicals and antioxidants in normal physiological functions and human disease. Int J Biochem Cell Biol 39, 44-84.
-
(2007)
Int J Biochem Cell Biol
, vol.39
, pp. 44-84
-
-
Valko, M.1
Leibfritz, D.2
Moncol, J.3
Mtd, C.4
Mazur, M.5
Telser, J.6
-
15
-
-
0035341254
-
Mitochondrial abnormalities in Alzheimer's disease
-
Hirai K, Aliev G, Nunomura A, Fujioka H, Russell RL, Atwood CS, Johnson AB, Kress Y, Vinters HV, Tabaton M, Shi- mohama S, Cash AD, Siedlak SL, Harris PLR, Jones PK, Petersen RB, Perry G, Smith MA (2001) Mitochondrial abnormalities in Alzheimer's disease. J Neurosci 21, 3017-3023.
-
(2001)
J Neurosci
, vol.21
, pp. 3017-3023
-
-
Hirai, K.1
Aliev, G.2
Nunomura, A.3
Fujioka, H.4
Russell, R.L.5
Atwood, C.S.6
Johnson, A.B.7
Kress, Y.8
Vinters, H.V.9
Tabaton, M.10
Shi- Mohama, S.11
Cash, A.D.12
Siedlak, S.L.13
Plr, H.14
Jones, P.K.15
Petersen, R.B.16
Perry, G.17
Smith, M.A.18
-
16
-
-
34247868874
-
Increased isoprostane and prostaglandin are prominent in neurons in Alzheimer disease
-
Casadesus G, Smith MA, Basu S, Hua J, Capobianco DE, Siedlak SL, Zhu XW, Perry G (2007) Increased isoprostane and prostaglandin are prominent in neurons in Alzheimer disease. Mol Neurodegener 2, 8.
-
(2007)
Mol Neurodegener
, vol.2
, pp. 8
-
-
Casadesus, G.1
Smith, M.A.2
Basu, S.3
Hua, J.4
Capobianco, D.E.5
Siedlak, S.L.6
Zhu, X.W.7
Perry, G.8
-
17
-
-
20444383489
-
Ribosomal RNA in Alzheimer disease is oxidized by bound redox-active iron
-
Honda K, Smith MA, Zhu XW, Baus D, Merrick WC, Tar- takoff AM, Hattier T, Harris PL, Siedlak SL, Fujioka H, Liu Q, Moreira PI, Miller FP, Nunomura A, Shimohama S, Perry G (2005) Ribosomal RNA in Alzheimer disease is oxidized by bound redox-active iron. J Biol Chem 280, 20978-20986.
-
(2005)
J Biol Chem
, vol.280
, pp. 20978-20986
-
-
Honda, K.1
Smith, M.A.2
Zhu, X.W.3
Baus, D.4
Merrick, W.C.5
Tar- Takoff, A.M.6
Hattier, T.7
Harris, P.L.8
Siedlak, S.L.9
Fujioka, H.10
Liu, Q.11
Moreira, P.I.12
Miller, F.P.13
Nunomura, A.14
Shimohama, S.15
Perry, G.16
-
18
-
-
0035875690
-
Increased lipid peroxidation precedes amyloid plaque formation in an animal model of Alzheimer amyloidosis
-
Pratico D, Uryu K, Leight S, Trojanowswki JQ, Lee VMY, Increased lipid peroxidation precedes amyloid plaque formation in an animal model of Alzheimer amyloidosis. J Neurosci 21, 4183-4187.
-
J Neurosci
, vol.21
, pp. 4183-4187
-
-
Pratico, D.1
Uryu, K.2
Leight, S.3
Trojanowswki, J.Q.4
Vmy, L.5
-
19
-
-
0032849357
-
Oxidative stress is associated with region-specific neuronal death during thiamine deficiency
-
Calingasan NY, Chun WJ, Park LCH, Uchida K, Gibson GE (1999) Oxidative stress is associated with region-specific neuronal death during thiamine deficiency. J. Neuropathol Exp Neurol 58, 946-958.
-
(1999)
J. Neuropathol Exp Neurol
, vol.58
, pp. 946-958
-
-
Calingasan, N.Y.1
Chun, W.J.2
Lch, P.3
Uchida, K.4
Gibson, G.E.5
-
20
-
-
0031944692
-
Evidence of oxidative stress and in vivo neurotoxicity of beta-amyloid in a transgenic mouse model of Alzheimer's disease - A chronic oxidative paradigm for testing antioxidant therapies in vivo
-
Pappolla MA, Chyan YJ, Omar RA, Hsiao K, Perry G, Smith MA, Bozner P (1998) Evidence of oxidative stress and in vivo neurotoxicity of beta-amyloid in a transgenic mouse model of Alzheimer's disease - A chronic oxidative paradigm for testing antioxidant therapies in vivo. Am J Pathol 152, 871877.
-
(1998)
Am J Pathol
, vol.152
, pp. 871-877
-
-
Pericak-Vance, M.A.1
Chyan, Y.J.2
Omar, R.A.3
Hsiao, K.4
Perry, G.5
Smith, M.A.6
Bozner, P.7
-
21
-
-
0031981072
-
Amyloid-beta deposition in Alzheimer transgenic mice is associated with oxida- tive stress
-
Smith MA, Hirai K, Hsiao K, Pappolla MA, Harris PLR, Siedlak SL, Tabaton M, Perry G (1998) Amyloid-beta deposition in Alzheimer transgenic mice is associated with oxida- tive stress. J Neurochem 70, 2212-2215.
-
(1998)
J Neurochem
, vol.70
, pp. 2212-2215
-
-
Smith, M.A.1
Hirai, K.2
Hsiao, K.3
Pericak-Vance, M.A.4
Plr, H.5
Siedlak, S.L.6
Tabaton, M.7
Perry, G.8
-
22
-
-
0035859221
-
Fib- rillar beta-amyloid evokes oxidative damage in a transgenic mouse model of Alzheimer's disease
-
Matsuoka Y, Picciano M, La Francois J, Duff K (2001) Fib- rillar beta-amyloid evokes oxidative damage in a transgenic mouse model of Alzheimer's disease. Neuroscience 104, 609613.
-
(2001)
Neuroscience
, vol.104
, pp. 609-613
-
-
Matsuoka, Y.1
Picciano, M.2
La Francois, J.3
Duff, K.4
-
23
-
-
11144353586
-
ABAD directly links A beta to mitochondrial toxicity in Alzheimer's disease
-
Lustbader JW, Cirilli M, Lin C, Xu HW, Takuma K, Wang N, Caspersen C, Chen X, Pollak S, Chaney M, Trinchese F, Liu SM, Gunn-Moore F, Lue LF, Walker DG, Kuppusamy P, Zewier ZL, Arancio O, Stern D, Yan SSD, Wu H (2004) ABAD directly links A beta to mitochondrial toxicity in Alzheimer's disease. Science 304, 448-452.
-
(2004)
Science
, vol.304
, pp. 448-452
-
-
Lustbader, J.W.1
Cirilli, M.2
Lin, C.3
Xu, H.W.4
Takuma, K.5
Wang, N.6
Caspersen, C.7
Chen, X.8
Pollak, S.9
Chaney, M.10
Trinchese, F.11
Liu, S.M.12
Gunn-Moore, F.13
Lue, L.F.14
Walker, D.G.15
Kuppusamy, P.16
Zewier, Z.L.17
Arancio, O.18
Stern, D.19
Ssd, Y.20
Wu, H.21
more..
-
24
-
-
0036403838
-
Oxidative Stress Increases Expression and Activity of BACE in NT2 Neurons
-
Tamagno E, Bardini P, Obbili A, Vitali A, Borghi R, Zaccheo D, Pronzato MA, Danni O, Smith MA, Perry G, Tabaton M. Oxidative stress increases expression and activity of BACE in NT2 neurons. Neurobiol Dis 10, 279-288.
-
Neurobiol Dis
, vol.10
, pp. 279-288
-
-
Tamagno, E.1
Bardini, P.2
Obbili, A.3
Vitali, A.4
Borghi, R.5
Zaccheo, D.6
Pericak-Vance, M.A.7
Danni, O.8
Smith, M.A.9
Perry, G.10
Tabaton, M.11
-
25
-
-
67649687124
-
The Alzheimer's disease mitochondrial cascade hypothesis: An update
-
Swerdlow RH, Khan SM (2009) The Alzheimer's disease mitochondrial cascade hypothesis: An update. Exp Neurol 218, 308-315.
-
(2009)
Exp Neurol
, vol.218
, pp. 308-315
-
-
Swerdlow, R.H.1
Khan, S.M.2
-
26
-
-
5444229093
-
Oxidative damage in cultured human olfactory neurons from Alzheimer's disease patients
-
Ghanbari HA, Ghanbari K, Harris PLR, Jones PK, Kubat Z, Castellani RJ, Wolozin BL, Smith MA, Perry G (2004) Oxidative damage in cultured human olfactory neurons from Alzheimer's disease patients. Aging Cell 3, 41-44.
-
(2004)
Aging Cell
, vol.3
, pp. 41-44
-
-
Ghanbari, H.A.1
Ghanbari, K.2
Plr, H.3
Jones, P.K.4
Kubat, Z.5
Castellani, R.J.6
Wolozin, B.L.7
Smith, M.A.8
Perry, G.9
-
27
-
-
13644270565
-
Oxidative DNA damage in peripheral leukocytes of mild cognitive impairment and AD patients
-
Mighore L, Fontana I, Trippi F, Colognato R, Coppede F, Tognoni G, Nucciarone B, Siciliano G (2005) Oxidative DNA damage in peripheral leukocytes of mild cognitive impairment and AD patients. Neurobiol Aging 26, 567-573.
-
(2005)
Neurobiol Aging
, vol.26
, pp. 567-573
-
-
Mighore, L.1
Fontana, I.2
Trippi, F.3
Colognato, R.4
Coppede, F.5
Tognoni, G.6
Nucciarone, B.7
Siciliano, G.8
-
28
-
-
34848890388
-
Lipoic acid and n-acetyl cysteine decrease mitochondrial-related oxidative stress in Alzheimer disease patient fibroblasts
-
Moreira PI, Harris PLR, Zhu XW, Santos MS, Oliveira CR, Smith MA, Perry G (2007) Lipoic acid and n-acetyl cysteine decrease mitochondrial-related oxidative stress in Alzheimer disease patient fibroblasts. JAlzheimers Dis 12, 195-206.
-
(2007)
JAlzheimers Dis
, vol.12
, pp. 195-206
-
-
Moreira, P.I.1
Plr, H.2
Zhu, X.W.3
Santos, M.S.4
Oliveira, C.R.5
Smith, M.A.6
Perry, G.7
-
29
-
-
10744231081
-
Oxidative damage in the olfactory system in Alzheimer's disease
-
Perry G, Castellani RJ, Smith MA, Harris PLR, Kubat Z, Ghanbari K, Jones PK, Cordone G, Tabaton M, Wolozin B, Ghanbari H (2003) Oxidative damage in the olfactory system in Alzheimer's disease. Acta Neuropathol 106, 552-556.
-
(2003)
Acta Neuropathol
, vol.106
, pp. 552-556
-
-
Perry, G.1
Castellani, R.J.2
Smith, M.A.3
Plr, H.4
Kubat, Z.5
Ghanbari, K.6
Jones, P.K.7
Cordone, G.8
Tabaton, M.9
Wolozin, B.10
Ghanbari, H.11
-
30
-
-
0024954067
-
Calcium, membranes, aging, and Alzheimers-disease - Introduction overview
-
Khachaturian ZS (1989) Calcium, membranes, aging, and Alzheimers-disease - introduction overview Ann N Y Acad Sci 568, 1-4.
-
(1989)
Ann N y Acad Sci
, vol.568
, pp. 1-4
-
-
Khachaturian, Z.S.1
-
31
-
-
45249117227
-
Mechanism of Ca2+ disruption in Alzheimer's disease by presenilin regulation ofInsP(3) receptor channel gating
-
Cheung KH, Shineman D, Muller M, Cardenas C, Mei LJ, Yang J, Tomita T, Iwatsubo T, Lee VMY, Foskett J.K. (2008) Mechanism of Ca2+ disruption in Alzheimer's disease by presenilin regulation ofInsP(3) receptor channel gating. Neuron 58, 871-883.
-
(2008)
Neuron
, vol.58
, pp. 871-883
-
-
Cheung, K.H.1
Shineman, D.2
Muller, M.3
Cardenas, C.4
Mei, L.J.5
Yang, J.6
Tomita, T.7
Iwatsubo, T.8
Vmy, L.9
Foskett, J.K.10
-
32
-
-
47749113650
-
A beta plaques lead to aberrant regulation of calcium homeostasis in vivo resulting in structural and functional disruption ofneuronal networks
-
Kuchibhotla KV, Goldman ST, Lattarulo CR, Wu HY, Hy- man BT, Bacskai BJ (2008) A beta plaques lead to aberrant regulation of calcium homeostasis in vivo resulting in structural and functional disruption ofneuronal networks. Neuron 59, 214-225.
-
(2008)
Neuron
, vol.59
, pp. 214-225
-
-
Kuchibhotla, K.V.1
Goldman, S.T.2
Lattarulo, C.R.3
Wu, H.Y.4
Hy- Man, B.T.5
Bacskai, B.J.6
-
33
-
-
72849144675
-
Calcium in the initiation, progression and as an effector of Alzheimer's disease pathology
-
Green KN (2009) Calcium in the initiation, progression and as an effector of Alzheimer's disease pathology. J Cell Mol Med 13, 2787-2799.
-
(2009)
J Cell Mol Med
, vol.13
, pp. 2787-2799
-
-
Green, K.N.1
-
34
-
-
47749095383
-
Linking calcium to A beta and Alzheimer's disease
-
Green KN, LaFerla FM (2008) Linking calcium to A beta and Alzheimer's disease. Neuron 59, 190-194.
-
(2008)
Neuron
, vol.59
, pp. 190-194
-
-
Green, K.N.1
Laferla, F.M.2
-
35
-
-
50249135503
-
Neuronal calcium mishandling and the pathogenesis of Alzheimer's disease
-
Bezprozvanny I, Mattson MP (2008) Neuronal calcium mishandling and the pathogenesis of Alzheimer's disease. Trends Neurosci 31, 454-463.
-
(2008)
Trends Neurosci
, vol.31
, pp. 454-463
-
-
Bezprozvanny, I.1
Mattson, M.P.2
-
36
-
-
1542377619
-
Toxicity of amyloid beta peptide: Tales of calcium, mitochondria, and oxidative stress
-
Canevari L, Abramov AY, Duchen MR (2004) Toxicity of amyloid beta peptide: tales of calcium, mitochondria, and oxidative stress. Neurochem Res 29, 637-650.
-
(2004)
Neurochem Res
, vol.29
, pp. 637-650
-
-
Canevari, L.1
Abramov, A.Y.2
Duchen, M.R.3
-
37
-
-
57049143140
-
Mitochondria in neuroplasticity and neurological disorders
-
Mattson MP, Gleichmann M, Cheng A (2008) Mitochondria in neuroplasticity and neurological disorders. Neuron 60, 748-766.
-
(2008)
Neuron
, vol.60
, pp. 748-766
-
-
Mattson, M.P.1
Gleichmann, M.2
Cheng, A.3
-
38
-
-
0034668833
-
Mitochondria and calcium: From cell signalling to cell death
-
Duchen MR (2000) Mitochondria and calcium: from cell signalling to cell death. J Physiol Lond 529, 57-68.
-
(2000)
J Physiol Lond
, vol.529
, pp. 57-68
-
-
Duchen, M.R.1
-
39
-
-
68649104009
-
Mitochondrial calcium function and dysfunction in the central nervous system
-
Nicholls DG (2009) Mitochondrial calcium function and dysfunction in the central nervous system. Biochim Biophys Acta 1787, 1416-1424.
-
(2009)
Biochim Biophys Acta
, vol.1787
, pp. 1416-1424
-
-
Nicholls, D.G.1
-
40
-
-
0034668946
-
Mitochondria as all-round players of the calcium game
-
Rizzuto R, Bernardi P, Pozzan T (2000) Mitochondria as all-round players of the calcium game. J Physiol Lond 529, 37-47.
-
(2000)
J Physiol Lond
, vol.529
, pp. 37-47
-
-
Rizzuto, R.1
Bernardi, P.2
Pozzan, T.3
-
41
-
-
85047676686
-
Control of mitochondrial ATP synthase in heart-cells - Inactive to active transitions caused by beating or positive inotropic agents
-
Das AM, Harris DA (1990) Control of mitochondrial ATP synthase in heart-cells - inactive to active transitions caused by beating or positive inotropic agents. Cardiovasc Res 24, 411-417.
-
(1990)
Cardiovasc Res
, vol.24
, pp. 411-417
-
-
Das, A.M.1
Harris, D.A.2
-
42
-
-
0018363365
-
Effects of calcium- ions and adenine-nucleotides on the activity of pig-heart 2- oxoglutarate dehydrogenase complex
-
McCormack JG, Denton RM (1979) Effects of calcium- ions and adenine-nucleotides on the activity of pig-heart 2- oxoglutarate dehydrogenase complex Biochem J 180, 533544.
-
(1979)
Biochem J
, vol.180
, pp. 533-544
-
-
McCormack, J.G.1
Denton, R.M.2
-
43
-
-
0028823895
-
Calcium indirectly increases the control exerted by the adenine nucleotide translocator over 2-oxoglutarate oxidation in rat heart mitochondria
-
Mildaziene V, Baniene R, Nauciene Z, Bakker BM, Brown GC, Westerhoff HV, Kholodenko BN (1995) Calcium indirectly increases the control exerted by the adenine nucleotide translocator over 2-oxoglutarate oxidation in rat heart mitochondria. Arch Biochem Biophys 324, 130-134.
-
(1995)
Arch Biochem Biophys
, vol.324
, pp. 130-134
-
-
Mildaziene, V.1
Baniene, R.2
Nauciene, Z.3
Bakker, B.M.4
Brown, G.C.5
Westerhoff, H.V.6
Kholodenko, B.N.7
-
44
-
-
4544235673
-
Calcium, ATP, and ROS: A mitochondrial love-hate triangle
-
Brookes PS, Yoon YS, Robotham JL, Anders MW, Sheu SS (2004) Calcium, ATP, and ROS: a mitochondrial love-hate triangle. Am J Physiol Cell Physiol 287, C817-C833.
-
(2004)
Am J Physiol Cell Physiol
, vol.287
-
-
Brookes, P.S.1
Yoon, Y.S.2
Robotham, J.L.3
Anders, M.W.4
Sheu, S.S.5
-
45
-
-
63849184477
-
Crosstalk signaling between mitochondrial Ca2+ and ROS
-
Feissner RF, Skalska J, Gaum WE, Sheu SS (2009) Crosstalk signaling between mitochondrial Ca2+ and ROS. Front Biosci 14, 1197-1218.
-
(2009)
Front Biosci
, vol.14
, pp. 1197-1218
-
-
Feissner, R.F.1
Skalska, J.2
Gaum, W.E.3
Sheu, S.S.4
-
46
-
-
3142777700
-
Shift in the localization of sites of hydrogen peroxide production in brain mitochondria by mitochondrial stress
-
Gyulkhandanyan AV, Pennefather PS (2004) Shift in the localization of sites of hydrogen peroxide production in brain mitochondria by mitochondrial stress. J Neurochem 90, 405421.
-
(2004)
J Neurochem
, vol.90
, pp. 405-421
-
-
Gyulkhandanyan, A.V.1
Pennefather, P.S.2
-
48
-
-
0036788941
-
Regulation of hydrogen peroxide production by brain mitochondria by calcium and Bax
-
Starkov AA, Polster BM, Fiskum G (2002) Regulation of hydrogen peroxide production by brain mitochondria by calcium and Bax. J Neurochem 83, 220-228.
-
(2002)
J Neurochem
, vol.83
, pp. 220-228
-
-
Starkov, A.A.1
Polster, B.M.2
Fiskum, G.3
-
49
-
-
0027933701
-
Isolated cerebral and cerebellar mitochondria produce free-radicals when exposed to elevated Ca2+ and Na+ - Implications for neurodegeneration
-
Dykens JA (1994) Isolated cerebral and cerebellar mitochondria produce free-radicals when exposed to elevated Ca2+ and Na+ - implications for neurodegeneration J Neurochem 63, 584-591.
-
(1994)
J Neurochem
, vol.63
, pp. 584-591
-
-
Dykens, J.A.1
-
50
-
-
46449116985
-
Calcium-induced generation of reactive oxygen species in brain mitochondria is mediated by permeability transition
-
Hansson MJ, Mansson R, Morota S, Uchino H, Kallur T, Sumi T, Ishii N, Shimazu M, Keep MF, Jegorov A, Elmer E (2008) Calcium-induced generation of reactive oxygen species in brain mitochondria is mediated by permeability transition. Free Radic Biol Med 45, 284-294.
-
(2008)
Free Radic Biol Med
, vol.45
, pp. 284-294
-
-
Hansson, M.J.1
Mansson, R.2
Morota, S.3
Uchino, H.4
Kallur, T.5
Sumi, T.6
Ishii, N.7
Shimazu, M.8
Keep, M.F.9
Jegorov, A.10
Elmer, E.11
-
51
-
-
0028821028
-
Ca2+- induced mitochondrial-membrane permeabilization - Role of coenzyme-Q redox state
-
Kowaltowski AJ, Castilho RF, Vercesi AE (1995) Ca2+- induced mitochondrial-membrane permeabilization - role of coenzyme-Q redox state. Am J Physiol Cell Physiol 269, C141-C147.
-
(1995)
Am J Physiol Cell Physiol
, vol.269
-
-
Kowaltowski, A.J.1
Castilho, R.F.2
Vercesi, A.E.3
-
52
-
-
0030047794
-
Opening of the mitochondrial permeability transition pore by uncoupling or inorganic phosphate in the presence of Ca2+ is dependent on mitochondrial-generated reactive oxygen species
-
Kowaltowski AJ, Castilho RF, Vercesi AE (1996) Opening of the mitochondrial permeability transition pore by uncoupling or inorganic phosphate in the presence of Ca2+ is dependent on mitochondrial-generated reactive oxygen species. FEBS Lett 378, 150-152.
-
(1996)
FEBS Lett
, vol.378
, pp. 150-152
-
-
Kowaltowski, A.J.1
Castilho, R.F.2
Vercesi, A.E.3
-
53
-
-
24144464489
-
Production of reactive oxygen species in brain mitochondria: Contribution by electron transport chain and non-electron transport chain sources
-
Adam-Vizi V (2005) Production of reactive oxygen species in brain mitochondria: Contribution by electron transport chain and non-electron transport chain sources. Antioxid Redox Signal 7, 1140-1149.
-
(2005)
Antioxid Redox Signal
, vol.7
, pp. 1140-1149
-
-
Adam-Vizi, V.1
-
54
-
-
33751072935
-
Bioenergetics and the formation of mitochondrial reactive oxygen species
-
Adam-Vizi V, Chinopoulos C (2006) Bioenergetics and the formation of mitochondrial reactive oxygen species. Trends Pharmacol Sci 27, 639-645.
-
(2006)
Trends Pharmacol Sci
, vol.27
, pp. 639-645
-
-
Adam-Vizi, V.1
Chinopoulos, C.2
-
56
-
-
0015882341
-
The mitochondrial generation of hydrogen peroxide. General properties and effect of hy- perbaric oxygen
-
Boveris A, Chance B (1973) The mitochondrial generation of hydrogen peroxide. General properties and effect of hy- perbaric oxygen. Biochem J134, 707-716.
-
(1973)
Biochem J134
, pp. 707-716
-
-
Boveris, A.1
Chance, B.2
-
57
-
-
0018776894
-
Hydroperoxide metabolism in mammalian organs
-
Chance B, Sies H, Boveris A (1979) Hydroperoxide metabolism in mammalian organs. Physiol Rev 59, 527-605.
-
(1979)
Physiol Rev
, vol.59
, pp. 527-605
-
-
Chance, B.1
Sies, H.2
Boveris, A.3
-
58
-
-
0036086130
-
Free radicals in the physiological control of cell function
-
Droge W (2002) Free radicals in the physiological control of cell function. Physiol Rev 82, 47-95.
-
(2002)
Physiol Rev
, vol.82
, pp. 47-95
-
-
Droge, W.1
-
59
-
-
67649866121
-
Mitochondria and reactive oxygen species
-
Kowaltowski AJ, de Souza-Pinto NC, Castilho RF, Vercesi AE (2009) Mitochondria and reactive oxygen species. Free Radic Biol Med 47, 333-343.
-
(2009)
Free Radic Biol Med
, vol.47
, pp. 333-343
-
-
Kowaltowski, A.J.1
Schmechel, D.E.2
Ouza-Pinto, N.C.3
Castilho, R.F.4
Vercesi, A.E.5
-
60
-
-
58249093939
-
How mitochondria produce reactive oxygen species
-
Murphy M (2008) How mitochondria produce reactive oxygen species. Biochem J 417, 1-13.
-
(2008)
Biochem J
, vol.417
, pp. 1-13
-
-
Murphy, M.1
-
62
-
-
33749999563
-
Protein-mediated energy-dissipating pathways in mitochondria
-
Starkov AA (2006) Protein-mediated energy-dissipating pathways in mitochondria. Chem Biol Interact 163, 133-144.
-
(2006)
Chem Biol Interact
, vol.163
, pp. 133-144
-
-
Starkov, A.A.1
-
63
-
-
85009039297
-
Technique monitors oxidative stress
-
Turrens JF (2003) Technique monitors oxidative stress. Photonics Spectra 37, 42-42
-
(2003)
Photonics Spectra
, vol.37
, pp. 42-42
-
-
Turrens, J.F.1
-
64
-
-
0017154414
-
Role of ubiquinone in mitochondrial generation of hydrogen- peroxide
-
Boveris A, Cadenas E, Stoppani AOM (1976) Role of ubiquinone in mitochondrial generation of hydrogen- peroxide. Biochem J 156, 435-444.
-
(1976)
Biochem J
, vol.156
, pp. 435-444
-
-
Boveris, A.1
Cadenas, E.2
Aom, S.3
-
65
-
-
0017406503
-
Production ofsuperoxide radicals and hydrogen-peroxide by NADH-ubiquinone reductase and ubiquinol-cytochrome c reductase from beef-heart mitochondria
-
Cadenas E, Boveris A, Ragan CI, Stoppani AOM (1977) Production ofsuperoxide radicals and hydrogen-peroxide by NADH-ubiquinone reductase and ubiquinol-cytochrome c reductase from beef-heart mitochondria. Arch Biochem Bio- phys 180, 248-257.
-
(1977)
Arch Biochem Bio- Phys
, vol.180
, pp. 248-257
-
-
Cadenas, E.1
Boveris, A.2
Ragan, C.I.3
Aom, S.4
-
66
-
-
0021996572
-
Ubisemiquinone is the electron-donor for superoxide formation by complex III of heart-mitochondria
-
Turrens JF, Alexandre A, Lehninger AL (1985) Ubisemiquinone is the electron-donor for superoxide formation by complex III of heart-mitochondria. Arch Biochem Biophys 237, 408-414.
-
(1985)
Arch Biochem Biophys
, vol.237
, pp. 408-414
-
-
Turrens, J.F.1
Alexandre, A.2
Lehninger, A.L.3
-
67
-
-
0019083215
-
Generation of superoxide an- ion by NADH dehydrogenase ofbovine heart-mitochondria
-
Turrens JF, Boveris A (1980) Generation of superoxide an- ion by NADH dehydrogenase ofbovine heart-mitochondria. Biochem J191, 421-427.
-
(1980)
Biochem J
, vol.191
, pp. 421-427
-
-
Turrens, J.F.1
Boveris, A.2
-
68
-
-
57649233079
-
The role ofmitochondria in reactive oxygen species metabolism and signaling
-
Gibson GE, Ratan RR, Beal MF, eds. Blackwell Publishing, Oxford
-
Starkov AA (2008) The role ofmitochondria in reactive oxygen species metabolism and signaling. In Mitochondria and Oxidative Stress in Neurodegenerative Disorders, Gibson GE, Ratan RR, Beal MF, eds. Blackwell Publishing, Oxford, pp. 37-52.
-
(2008)
Mitochondria and Oxidative Stress in Neurodegenerative Disorders
, pp. 37-52
-
-
Starkov, A.A.1
-
69
-
-
4544359913
-
Mitochondrial alpha-ketoglutarate dehydrogenase complex generates reactive oxygen species
-
Starkov AA, Fiskum G, Chinopoulos C, Lorenzo BJ, Browne SE, Patel MS, Beal MF (2004) Mitochondrial alpha-ketoglutarate dehydrogenase complex generates reactive oxygen species. J Neurosci 24, 7779-7788.
-
(2004)
J Neurosci
, vol.24
, pp. 7779-7788
-
-
Starkov, A.A.1
Fiskum, G.2
Chinopoulos, C.3
Lorenzo, B.J.4
Browne, S.E.5
Patel, M.S.6
Beal, M.F.7
-
70
-
-
4544226082
-
Generation of reactive oxygen species in the reaction catalyzed by alpha-ketoglutarate dehydrogenase
-
Tretter L, Adam-Vizi V (2004) Generation of reactive oxygen species in the reaction catalyzed by alpha-ketoglutarate dehydrogenase. J Neurosci 24, 7771-7778.
-
(2004)
J Neurosci
, vol.24
, pp. 7771-7778
-
-
Tretter, L.1
Adam-Vizi, V.2
-
71
-
-
0024548927
-
Generation of hydrogen- peroxide by brain mitochondria - The effect of reoxygenation following postdecapitative ischemia
-
Cino M, Delmaestro RF (1989) Generation of hydrogen- peroxide by brain mitochondria - the effect of reoxygenation following postdecapitative ischemia. Arch Biochem Biophys 269, 623-638.
-
(1989)
Arch Biochem Biophys
, vol.269
, pp. 623-638
-
-
Cino, M.1
Delmaestro, R.F.2
-
72
-
-
0034467677
-
Localization ofthe site ofoxygen radical generation inside the complex i of heart and nonsy- naptic brain mammalian mitochondria
-
Herrero A, Barja G (2000) Localization ofthe site ofoxygen radical generation inside the complex I of heart and nonsy- naptic brain mammalian mitochondria. J Bioenerg Biomemb 32, 609-615.
-
(2000)
J Bioenerg Biomemb
, vol.32
, pp. 609-615
-
-
Herrero, A.1
Barja, G.2
-
74
-
-
0034740585
-
Delta psi(m)-dependent and -independent production of reactive oxygen species by rat brain mitochondria
-
Votyakova TV, Reynolds IJ (2001) Delta psi(m)-dependent and -independent production of reactive oxygen species by rat brain mitochondria. J Neurochem 79, 266-277.
-
(2001)
J Neurochem
, vol.79
, pp. 266-277
-
-
Votyakova, T.V.1
Reynolds, I.J.2
-
75
-
-
0023811458
-
Pathways of hydrogen-peroxide generation in guinea-pig cerebral-cortex mitochondria
-
Zoccarato F, Cavallini L, Deana R, Alexandre A (1988) Pathways of hydrogen-peroxide generation in guinea-pig cerebral-cortex mitochondria. Biochem Biophys Res Com- mun 154, 727-734.
-
(1988)
Biochem Biophys Res Com- Mun
, vol.154
, pp. 727-734
-
-
Zoccarato, F.1
Cavallini, L.2
Deana, R.3
Alexandre, A.4
-
76
-
-
0037269343
-
Quantitative relationship between inhibition of respiratory complexes and formation of reactive oxygen species in isolated nerve terminals
-
Sipos I, Tretter L, Adam-Vizi V (2003) Quantitative relationship between inhibition of respiratory complexes and formation of reactive oxygen species in isolated nerve terminals. J Neurochemy 84, 112-118.
-
(2003)
J Neurochemy
, vol.84
, pp. 112-118
-
-
Sipos, I.1
Tretter, L.2
Adam-Vizi, V.3
-
77
-
-
0032716145
-
The regeneration of reduced glutathione in rat forebrain mitochondria identifies metabolic pathways providing the NADPH required
-
Vogel R, Wiesinger H, Hamprecht B, Dringen R (1999) The regeneration of reduced glutathione in rat forebrain mitochondria identifies metabolic pathways providing the NADPH required. Neurosci Lett 275, 97-100.
-
(1999)
Neurosci Lett
, vol.275
, pp. 97-100
-
-
Vogel, R.1
Wiesinger, H.2
Hamprecht, B.3
Dringen, R.4
-
78
-
-
0017332157
-
Effect of ammonia on mitochondrial and cytosolic NADH and NADPH systems in isolated rat-liver cells
-
Tischler ME, Hecht P, Williamson JR (1977) Effect of ammonia on mitochondrial and cytosolic NADH and NADPH systems in isolated rat-liver cells. FEBSLett 76, 99-104.
-
(1977)
FEBSLett
, vol.76
, pp. 99-104
-
-
Tischler, M.E.1
Hecht, P.2
Williamson, J.R.3
-
79
-
-
0018337607
-
Assay of citric acid cycle intermediates and related compounds - Update with tissue metabolite levels and intracellular distribution
-
Williamson J, Corkey B (1979) Assay of citric acid cycle intermediates and related compounds - update with tissue metabolite levels and intracellular distribution. Methods En- zymol 55, 200-222.
-
(1979)
Methods En- Zymol
, vol.55
, pp. 200-222
-
-
Williamson, J.1
Corkey, B.2
-
80
-
-
0001547757
-
Origin and turnover of mitochondrial glutathione
-
Griffith OW, Meister A (1985) Origin and turnover of mitochondrial glutathione. Proc Natl Acad Sci USA 82, 46684672.
-
(1985)
Proc Natl Acad Sci USA
, vol.82
, pp. 4668-4672
-
-
Griffith, O.W.1
Meister, A.2
-
81
-
-
0041326831
-
Effects of age and caloric restriction on glutathione redox state in mice
-
Rebrin I, Kamzalov S, Sohal RS (2003) Effects of age and caloric restriction on glutathione redox state in mice. Free Radic Biol Med 35, 626-635.
-
(2003)
Free Radic Biol Med
, vol.35
, pp. 626-635
-
-
Rebrin, I.1
Kamzalov, S.2
Sohal, R.S.3
-
82
-
-
6944220226
-
Comparison of thiol redox state ofmitochondria and homogenates ofvarious tissues between two strains of mice with different longevities
-
Rebrin I, Sohal RS (2004) Comparison of thiol redox state ofmitochondria and homogenates ofvarious tissues between two strains of mice with different longevities. Exp Gerontol 39, 1513-1519.
-
(2004)
Exp Gerontol
, vol.39
, pp. 1513-1519
-
-
Rebrin, I.1
Sohal, R.S.2
-
83
-
-
0018320433
-
Hepatic mitochondrial and cytosolic glutathione content and the subcellular-distribution of GSH-S-transferases
-
Wahllander A, Soboll S, Sies H, Linke I, Muller M (1979) Hepatic mitochondrial and cytosolic glutathione content and the subcellular-distribution of GSH-S-transferases. FEBS Lett 97, 138-140.
-
(1979)
FEBS Lett
, vol.97
, pp. 138-140
-
-
Wahllander, A.1
Soboll, S.2
Sies, H.3
Linke, I.4
Muller, M.5
-
84
-
-
1642540210
-
The mito- chondrial calcium uniporter is a highly selective ion channel
-
Kirichok Y, Krapivinsky G, Clapham DE (2004) The mito- chondrial calcium uniporter is a highly selective ion channel. Nature 427, 360-364.
-
(2004)
Nature
, vol.427
, pp. 360-364
-
-
Kirichok, Y.1
Krapivinsky, G.2
Capobianco, D.E.3
-
85
-
-
0035795178
-
The rapid mode of calcium uptake into heart mitochondria (RaM): Comparison to RaM in liver mitochondria
-
Buntinas L, Gunter KK, Sparagna GC, Gunter TE (2001) The rapid mode of calcium uptake into heart mitochondria (RaM): comparison to RaM in liver mitochondria. Biochim Biophys Acta 1504, 248-261.
-
(2001)
Biochim Biophys Acta
, vol.1504
, pp. 248-261
-
-
Buntinas, L.1
Gunter, K.K.2
Sparagna, G.C.3
Gunter, T.E.4
-
86
-
-
0028865759
-
Mi- tochondrial calcium-uptake from physiological-type pulses of calcium - A description of the rapid uptake mode
-
Sparagna GC, Gunter KK, Shen SS, Gunter TE (1995) Mi- tochondrial calcium-uptake from physiological-type pulses of calcium - a description of the rapid uptake mode J Biol Chem 270, 27510-27515.
-
(1995)
J Biol Chem
, vol.270
, pp. 27510-27515
-
-
Sparagna, G.C.1
Gunter, K.K.2
Shen, S.S.3
Gunter, T.E.4
-
87
-
-
27844439866
-
Type 1 ryanodine receptor in cardiac mitochondria: Transducer of excitation-metabolism coupling
-
Beutner G, Sharma VK, Lin L, Ryu SY, Dirksen RT, Sheu SS (2005) Type 1 ryanodine receptor in cardiac mitochondria: Transducer of excitation-metabolism coupling. Biochim Biophys Acta 1717, 1-10.
-
(2005)
Biochim Biophys Acta
, vol.1717
, pp. 1-10
-
-
Beutner, G.1
Sharma, V.K.2
Lin, L.3
Ryu, S.Y.4
Dirksen, R.T.5
Sheu, S.S.6
-
88
-
-
0034520615
-
Mitochondrial calcium transport: Mechanisms and functions
-
Gunter TE, Buntinas L, Sparagna G, Eliseev R, Gunter K (2000) Mitochondrial calcium transport: mechanisms and functions. Cell Calcium 28, 285-296.
-
(2000)
Cell Calcium
, vol.28
, pp. 285-296
-
-
Gunter, T.E.1
Buntinas, L.2
Sparagna, G.3
Eliseev, R.4
Gunter, K.5
-
89
-
-
0032827410
-
Mitochondrial transport of cations: Channels, exchangers, and permeability transition
-
Bernardi P (1999) Mitochondrial transport of cations: Channels, exchangers, and permeability transition. Physiol Rev 79, 1127-1155.
-
(1999)
Physiol Rev
, vol.79
, pp. 1127-1155
-
-
Bernardi, P.1
-
90
-
-
33646255246
-
The mitochondrial permeability transition from in vitro artifact to disease target
-
Bernardi P, Krauskopf A, Basso E, Petronilli V, Blalchy- Dyson E, Di Lisa F, Forte MA (2006) The mitochondrial permeability transition from in vitro artifact to disease target. FEBS J 273, 2077-2099.
-
(2006)
FEBS J
, vol.273
, pp. 2077-2099
-
-
Bernardi, P.1
Krauskopf, A.2
Basso, E.3
Petronilli, V.4
Blalchy- Dyson, E.5
Di Lisa, F.6
Forte, M.A.7
-
91
-
-
0033565557
-
The mitochondrial permeability transition pore and its role in cell death
-
Crompton M (1999) The mitochondrial permeability transition pore and its role in cell death. Biochem J 341, 233-249.
-
(1999)
Biochem J
, vol.341
, pp. 233-249
-
-
Crompton, M.1
-
92
-
-
0032504709
-
Elucidating the molecular mechanism of the permeability transition pore and its role in reperfusion injury ofthe heart
-
Halestrap AP, Kerr PM, Javadov S, Woodfield KY (1998) Elucidating the molecular mechanism of the permeability transition pore and its role in reperfusion injury ofthe heart. Biochim Biophys Acta 1366, 79-94.
-
(1998)
Biochim Biophys Acta
, vol.1366
, pp. 79-94
-
-
Halestrap, A.P.1
Kerr, P.M.2
Javadov, S.3
Woodfield, K.Y.4
-
93
-
-
0028941372
-
Permeabilization of the inner mitochondrial-membrane by Ca2+ ions is stimulated by T- butyl hydroperoxide and mediated by reactive oxygen species generated by mitochondria
-
Castilho RF, Kowaltowski AJ, Meinicke AR, Bechara EJH, Vercesi AE (1995) Permeabilization of the inner mitochondrial-membrane by Ca2+ ions is stimulated by T- butyl hydroperoxide and mediated by reactive oxygen species generated by mitochondria. Free Radic Biol Med 18, 479486.
-
(1995)
Free Radic Biol Med
, vol.18
, pp. 479486
-
-
Castilho, R.F.1
Kowaltowski, A.J.2
Meinicke, A.R.3
Ejh, B.4
Vercesi, A.E.5
-
94
-
-
62149131085
-
Mitochondrial calcium overload triggers complement-dependent superoxide-mediated programmed cell death in Trypanosoma cruzi
-
Irigoin F, Inada NM, Fernandes MP, Piacenza L, Gadelha FR, Vercesi AE, Radi R (2009) Mitochondrial calcium overload triggers complement-dependent superoxide-mediated programmed cell death in Trypanosoma cruzi. Biochem J 418, 595-604.
-
(2009)
Biochem J
, vol.418
, pp. 595-604
-
-
Irigoin, F.1
Inada, N.M.2
Fernandes, M.P.3
Piacenza, L.4
Gadelha, F.R.5
Vercesi, A.E.6
Radi, R.7
-
95
-
-
33847041066
-
Species- and tissue- specific relationships between mitochondrial permeability transition and generation of ROS in brain and liver mitochondria of rats and mice
-
Panov A, Dikalov S, Shalbuyeva N, Hemendinger R, Greenamyre JT, Rosenfeld J (2007) Species- and tissue- specific relationships between mitochondrial permeability transition and generation of ROS in brain and liver mitochondria of rats and mice. Am J Physiol Cell Physiol 292, C708-C718.
-
(2007)
Am J Physiol Cell Physiol
, vol.292
-
-
Panov, A.1
Dikalov, S.2
Shalbuyeva, N.3
Hemendinger, R.4
Greenamyre, J.T.5
Rosenfeld, J.6
-
96
-
-
33846191139
-
Ca2+ storage capacity of rat brain mitochondria declines during the postnatal development without change in ROS production capacity
-
Schonfeld P, Reiser G (2007) Ca2+ storage capacity of rat brain mitochondria declines during the postnatal development without change in ROS production capacity. Antioxid Redox Signal 9, 191-199.
-
(2007)
Antioxid Redox Signal
, vol.9
, pp. 191-199
-
-
Schonfeld, P.1
Reiser, G.2
-
97
-
-
18144427184
-
Ca2+-induced permeabi- lization promotes free radical release from rat brain mitochondria with partially inhibited complex i
-
Votyakova TV, Reynolds IJ (2005) Ca2+-induced permeabi- lization promotes free radical release from rat brain mitochondria with partially inhibited complex I. J Neurochem 93, 526-537.
-
(2005)
J Neurochem
, vol.93
, pp. 526-537
-
-
Votyakova, T.V.1
Reynolds, I.J.2
-
98
-
-
33646716659
-
The mechanism of superoxide production by NADH: Ubiquinone oxidoreductase (complex I) from bovine heart mitochondria
-
Kussmaul L, Hirst J (2006) The mechanism of superoxide production by NADH: ubiquinone oxidoreductase (complex I) from bovine heart mitochondria. Proc Natl Acad Sci U S A 103, 7607-7612.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 7607-7612
-
-
Kussmaul, L.1
Hirst, J.2
-
99
-
-
1042301416
-
Characterization of superoxide-producing sites in isolated brain mitochondria
-
Kudin AP, Bimpong-ButaNYB, Vielhaber S, Elger CE, Kunz WS (2004) Characterization of superoxide-producing sites in isolated brain mitochondria. J Biol Chem 279, 4127-4135.
-
(2004)
J Biol Chem
, vol.279
, pp. 4127-4135
-
-
Kudin, A.P.1
Bimpong-Butanyb Vielhaber, S.2
Elger, C.E.3
Kunz, W.S.4
-
100
-
-
0036903625
-
Complex I-mediated reactive oxygen species generation: Modulation by cytochrome c and NAD(P)(+) oxidation-reduction state
-
Kushnareva Y, Murphy AN, Andreyev A (2002) Complex I-mediated reactive oxygen species generation: modulation by cytochrome c and NAD(P)(+) oxidation-reduction state. Biochem J 368, 545-553.
-
(2002)
Biochem J
, vol.368
, pp. 545-553
-
-
Kushnareva, Y.1
Murphy, A.N.2
Andreyev, A.3
-
101
-
-
72949139589
-
The interaction of energy and electron transfer reactions in mitochondria. I. General properties and nature of the products of succinate-linked reduction of pyridine nucleotide
-
Chance B, Hollunger G (1961) The interaction of energy and electron transfer reactions in mitochondria. I. General properties and nature of the products of succinate-linked reduction of pyridine nucleotide. J Biol Chem 236, 1534-1543.
-
(1961)
J Biol Chem
, vol.236
, pp. 1534-1543
-
-
Chance, B.1
Hollunger, G.2
-
102
-
-
0014217470
-
Partial resolution of the enzymes catalyzing oxidative phosphorylation. XV. Reverse electron transfer in the flavin-cytochrome beta region of the respiratory chain of beef heart submitochondrial particles
-
Hinkle P, Butow R, Racker E, Chance B (1967) Partial resolution of the enzymes catalyzing oxidative phosphorylation. XV. Reverse electron transfer in the flavin-cytochrome beta region of the respiratory chain of beef heart submitochondrial particles. J Biol Chem 242, 5169-5173.
-
(1967)
J Biol Chem
, vol.242
, pp. 5169-5173
-
-
Hinkle, P.1
Butow, R.2
Racker, E.3
Chance, B.4
-
103
-
-
0036319021
-
Generation of reactive oxygen species by the mitochondrial electron transport chain
-
Liu YB, Fiskum G, Schubert D (2002) Generation of reactive oxygen species by the mitochondrial electron transport chain. J Neurochem 80, 780-787.
-
(2002)
J Neurochem
, vol.80
, pp. 780-787
-
-
Liu, Y.B.1
Fiskum, G.2
Schubert, D.3
-
105
-
-
0018664824
-
Influence ofsome biological pyrimidines on the succinate cycle during and after cerebral-ischemia
-
Benzi G, Arrigoni E, Marzatico F, Villa RF (1979) Influence ofsome biological pyrimidines on the succinate cycle during and after cerebral-ischemia Biochem Pharmacol 28, 25452550.
-
(1979)
Biochem Pharmacol
, vol.28
, pp. 2545-2550
-
-
Benzi, G.1
Arrigoni, E.2
Marzatico, F.3
Villa, R.F.4
-
106
-
-
0016302480
-
Influence of complete ischemia on glycolytic metabolites, citric acid cycle intermediates, and associated amino acids in the rat cerebral cortex
-
Folbergrova J, Ljunggren B, Norberg K, Siesjo B (1974) Influence of complete ischemia on glycolytic metabolites, citric acid cycle intermediates, and associated amino acids in the rat cerebral cortex. Brain Res 80, 265-279.
-
(1974)
Brain Res
, vol.80
, pp. 265-279
-
-
Folbergrova, J.1
Ljunggren, B.2
Norberg, K.3
Siesjo, B.4
-
107
-
-
0026619302
-
Air saturation ofthe medium reduces the rate ofphosphorylating oxidation of succinate in isolated-mitochondria
-
Khazanov VA, Poborsky AN, Kondrashova MN (1992) Air saturation ofthe medium reduces the rate ofphosphorylating oxidation of succinate in isolated-mitochondria. FEBS Lett 314, 264-266.
-
(1992)
FEBS Lett
, vol.314
, pp. 264-266
-
-
Khazanov, V.A.1
Poborsky, A.N.2
Kondrashova, M.N.3
-
108
-
-
0030632660
-
Effect of research conditions on succinate oxidation in brain mitochondria in circulatory hypoxia
-
Poborskii A (1997) Effect of research conditions on succinate oxidation in brain mitochondria in circulatory hypoxia. Patol Fiziol Eksp Ter 1, 10-12.
-
(1997)
Patol Fiziol Eksp ter
, vol.1
, pp. 10-12
-
-
Poborskii, A.1
-
109
-
-
0030729851
-
High pro- tonic potential actuates a mechanism of production of reactive oxygen species in mitochondria
-
Korshunov SS, Skulachev VP, Starkov AA (1997) High pro- tonic potential actuates a mechanism of production of reactive oxygen species in mitochondria. FEBSLett 416, 15-18.
-
(1997)
FEBSLett
, vol.416
, pp. 15-18
-
-
Korshunov, S.S.1
Skulachev, V.P.2
Starkov, A.A.3
-
111
-
-
24344508510
-
The topology of superoxide production by complex III and glycerol 3-phosphate dehydro- genase in Drosophila mitochondria
-
Miwa S, Brand MD (2005) The topology of superoxide production by complex III and glycerol 3-phosphate dehydro- genase in Drosophila mitochondria. Biochim Biophys Acta 1709,214-219.
-
(2005)
Biochim Biophys Acta
, vol.1709
, pp. 214-219
-
-
Miwa, S.1
Brand, M.D.2
-
113
-
-
0019888718
-
Ca2+ stimulation of rat-liver mitochondrial glycerophosphate dehydrogenase
-
Wernette ME, Ochs RS, Lardy HA (1981) Ca2+ stimulation of rat-liver mitochondrial glycerophosphate dehydrogenase. J Biol Chem 256, 2767-2771.
-
(1981)
J Biol Chem
, vol.256
, pp. 2767-2771
-
-
Wernette, M.E.1
Ochs, R.S.2
Lardy, H.A.3
-
114
-
-
0025650037
-
Thiamine-dependent enzyme changes in temporal cortex of patients with alzheimers-disease
-
Butterworth RF, Besnard AM (1990) Thiamine-dependent enzyme changes in temporal cortex of patients with alzheimers-disease. Metab Brain Dis 5, 179-184.
-
(1990)
Metab Brain Dis
, vol.5
, pp. 179-184
-
-
Butterworth, R.F.1
Besnard, A.M.2
-
115
-
-
71849095133
-
Cause and consequence: Mitochondrial dysfunction initiates and propagates neuronal dysfunction, neuronal death and behavioral abnormalities in age-associated neurodegenerative diseases
-
Gibson GE, Starkov A, Blass JP, Ratan RR, Beal MF (1988) Cause and consequence: Mitochondrial dysfunction initiates and propagates neuronal dysfunction, neuronal death and behavioral abnormalities in age-associated neurodegenerative diseases. Biochim Biophys Acta 1802, 122-134.
-
(1988)
Biochim Biophys Acta
, vol.1802
, pp. 122-134
-
-
Gibson, G.E.1
Starkov, A.2
Blass, J.P.3
Ratan, R.R.4
Beal, M.F.5
-
116
-
-
0029884010
-
Brain protein and alpha-ketoglutarate dehydrogenase complex activity in Alzheimer's disease
-
Mastrogiacomo F, Lindsay JG, Bettendorff L, Rice J, Kish SJ (1996) Brain protein and alpha-ketoglutarate dehydrogenase complex activity in Alzheimer's disease. Ann Neurol 39, 592598.
-
(1996)
Ann Neurol
, vol.39
, pp. 592-598
-
-
Mastrogiacomo, F.1
Lindsay, J.G.2
Bettendorff, L.3
Rice, J.4
Kish, S.J.5
-
117
-
-
71849095133
-
Cause and consequence: Mitochondrial dysfunction initiates and propagates neuronal dysfunction, neuronal death and behavioral abnormalities in age-associated neurodegenerative diseases
-
Gibson GE, Starkov A, Blass JP, Ratan RR, Beal MF (2010) Cause and consequence: Mitochondrial dysfunction initiates and propagates neuronal dysfunction, neuronal death and behavioral abnormalities in age-associated neurodegenerative diseases. Biochim Biophys Acta 1802, 122-134.
-
(2010)
Biochim Biophys Acta
, vol.1802
, pp. 122-134
-
-
Gibson, G.E.1
Starkov, A.2
Blass, J.P.3
Ratan, R.R.4
Beal, M.F.5
-
118
-
-
28744449206
-
Mitochondrial A beta: A potential focal point for neuronal metabolic dysfunction in Alzheimer's disease
-
Caspersen C, Wang N, Yao J, Sosunov A, Chen X, Lust- bader JW, Xu HW, Stern D, McKhann G, Yan SD (2005) Mitochondrial A beta: a potential focal point for neuronal metabolic dysfunction in Alzheimer's disease. FASEB J 19, 2040-2041.
-
(2005)
FASEB J
, vol.19
, pp. 2040-2041
-
-
Caspersen, C.1
Wang, N.2
Yao, J.3
Sosunov, A.4
Chen, X.5
Lust- Bader, J.W.6
Xu, H.W.7
Stern, D.8
McKhann, G.9
Yan, S.D.10
-
119
-
-
0036272650
-
Beta-amyloid inhibits integrated mitochondrial respiration and key enzyme activities
-
Casley CS, Canevari L, Land JM, Clark JB, Sharpe MA (2002) Beta-amyloid inhibits integrated mitochondrial respiration and key enzyme activities. J Neurochem 80, 91-100.
-
(2002)
J Neurochem
, vol.80
, pp. 91-100
-
-
Casley, C.S.1
Canevari, L.2
Land, J.M.3
Clark, J.B.4
Smith, M.A.5
-
120
-
-
0344443765
-
Oxidative alpha-ketoglutarate dehydrogenase inhibition via subtle elevations in monoamine oxidase B levels results in loss ofspare respiratory capacity - Implications for Parkinson's disease
-
Kumar MJ, Nicholls DG, Andersen JK (2003) Oxidative alpha-ketoglutarate dehydrogenase inhibition via subtle elevations in monoamine oxidase B levels results in loss ofspare respiratory capacity - Implications for Parkinson's disease. J Biol Chem 278, 46432-46439.
-
(2003)
J Biol Chem
, vol.278
, pp. 46432-46439
-
-
Kumar, M.J.1
Nicholls, D.G.2
Andersen, J.K.3
-
121
-
-
0035968183
-
Modulation of mito- chondrial function by hydrogen peroxide
-
Nulton-Persson AC, Szweda LI (2001) Modulation of mito- chondrial function by hydrogen peroxide. J Biol Chem 276, 23357-23361.
-
(2001)
J Biol Chem
, vol.276
, pp. 23357-23361
-
-
Nulton-Persson, A.C.1
Szweda, L.I.2
-
122
-
-
0034671429
-
Inhibition of Krebs cycle enzymes by hydrogen peroxide: A key role of alpha- ketoglutarate dehydrogenase in limiting NADH production under oxidative stress
-
Tretter L, Adam-Vizi V (2000) Inhibition of Krebs cycle enzymes by hydrogen peroxide: A key role of alpha- ketoglutarate dehydrogenase in limiting NADH production under oxidative stress. J Neurosci 20, 8972-8979.
-
(2000)
J Neurosci
, vol.20
, pp. 8972-8979
-
-
Tretter, L.1
Adam-Vizi, V.2
-
123
-
-
0033048258
-
Metabolic impairment induces oxidative stress, compromises inflammatory responses, and inactivates a key mitochondrial enzyme in microglia
-
Park LCH, Zhang H, Sheu KFR, Calingasan NY, Kristal BS, Lindsay JG, Gibson GE (1999) Metabolic impairment induces oxidative stress, compromises inflammatory responses, and inactivates a key mitochondrial enzyme in microglia. J Neurochem 72, 1948-1958.
-
(1999)
J Neurochem
, vol.72
, pp. 1948-1958
-
-
Lch, P.1
Zhang, H.2
Kfr, S.3
Calingasan, N.Y.4
Kristal, B.S.5
Lindsay, J.G.6
Gibson, G.E.7
-
124
-
-
0036408866
-
Inactivation of the 2-oxo acid de- hydrogenase complexes upon generation of intrinsic radical species
-
Bunik VI, Sievers C (2002) Inactivation of the 2-oxo acid de- hydrogenase complexes upon generation of intrinsic radical species. Eur J Biochem 269, 5004-5015.
-
(2002)
Eur J Biochem
, vol.269
, pp. 5004-5015
-
-
Bunik, V.I.1
Sievers, C.2
-
125
-
-
63349087445
-
Tissue-, substrate-, and site-specific characteristics of mitochondrial reactive oxygen species generation
-
Tahara EB, Navarete FDT, Kowaltowski AJ (2009) Tissue-, substrate-, and site-specific characteristics of mitochondrial reactive oxygen species generation. Free Radic Biol Med 46, 1283-1297.
-
(2009)
Free Radic Biol Med
, vol.46
, pp. 1283-1297
-
-
Tahara, E.B.1
Fdt, N.2
Kowaltowski, A.J.3
-
126
-
-
33745252231
-
Alpha-ketoglutarate dehydrogenase: A target and generator of oxidative stress
-
Tretter L, Adam-Vizi V (2005) Alpha-ketoglutarate dehydrogenase: a target and generator of oxidative stress. Philos T Roy Soc B 360, 2335-2345.
-
(2005)
Philos T Roy Soc B
, vol.360
, pp. 2335-2345
-
-
Tretter, L.1
Adam-Vizi, V.2
-
127
-
-
0024616270
-
Dihydrolipoamide dehydrogenase - Functional similarities and divergent evolution ofthe pyridine nucleotide-disulfide oxidoreductase
-
Carothers DJ, Pons G, Patel MS (1989) Dihydrolipoamide dehydrogenase - functional similarities and divergent evolution ofthe pyridine nucleotide-disulfide oxidoreductase Arch Biochem Biophys 268, 409-425.
-
(1989)
Arch Biochem Biophys
, vol.268
, pp. 409-425
-
-
Carothers, D.J.1
Pons, G.2
Patel, M.S.3
-
128
-
-
0030034832
-
Independent modulation of the activity of alpha-ketoglutarate dehydrogenase complex by Ca2+ and Mg2+
-
Panov A, Scarpa A (1996) Independent modulation of the activity of alpha-ketoglutarate dehydrogenase complex by Ca2+ and Mg2+. Biochem 35, 427-432.
-
(1996)
Biochem
, vol.35
, pp. 427-432
-
-
Panov, A.1
Scarpa, A.2
-
129
-
-
58149469744
-
Alpha- ketoglutarate dehydrogenase contributes to production ofre- active oxygen species in glutamate-stimulated hippocampal neurons in situ
-
Zundorf G, Kahlert S, Bunik VI, Reiser G (2009) Alpha- ketoglutarate dehydrogenase contributes to production ofre- active oxygen species in glutamate-stimulated hippocampal neurons in situ. Neuroscience 158, 610-616.
-
(2009)
Neuroscience
, vol.158
, pp. 610-616
-
-
Zundorf, G.1
Kahlert, S.2
Bunik, V.I.3
Reiser, G.4
-
130
-
-
0029827804
-
Mitochondria, calcium regulation, and acute glutamate excitotoxicity in cultured cerebellar granule cells
-
Budd SL, Nicholls DG (1996) Mitochondria, calcium regulation, and acute glutamate excitotoxicity in cultured cerebellar granule cells. J Neurochem 67, 2282-2291.
-
(1996)
J Neurochem
, vol.67
, pp. 2282-2291
-
-
Budd, S.L.1
Nicholls, D.G.2
-
131
-
-
5444219563
-
Inhibition of glutamate-induced delayed calcium deregulation by 2-APB and La3+ in cultured cortical neurones
-
Chinopoulos C, Gerencser AA, Doczi J, Fiskum G, Adam- Vizi V (2004) Inhibition of glutamate-induced delayed calcium deregulation by 2-APB and La3+ in cultured cortical neurones. J Neurochem 91, 471-483.
-
(2004)
J Neurochem
, vol.91
, pp. 471-483
-
-
Chinopoulos, C.1
Gerencser, A.A.2
Doczi, J.3
Fiskum, G.4
Adam- Vizi, V.5
-
132
-
-
0028882764
-
Mito- chondrial production of reactive oxygen species in cortical- neurons following exposure to N-Methyl-D-Aspartate
-
Dugan LL, Sensi SL, Canzoniero LMT, Handran SD, Roth- man SM, Lin TS, Goldberg MP, Choi DW (1995) Mito- chondrial production of reactive oxygen species in cortical- neurons following exposure to N-Methyl-D-Aspartate. J Neurosci 15, 6377-6388.
-
(1995)
J Neurosci
, vol.15
, pp. 6377-6388
-
-
Dugan, L.L.1
Sensi, S.L.2
Lmt, C.3
Handran, S.D.4
Roth- Man, S.M.5
Lin, T.S.6
Goldberg, M.P.7
Choi, D.W.8
-
133
-
-
0027221998
-
NMDA-dependent superoxide production and neurotoxicity
-
Lafoncazal M, Pietri S, Culcasi M, Bockaert J (1993) NMDA-dependent superoxide production and neurotoxicity. Nature 364, 535-537.
-
(1993)
Nature
, vol.364
, pp. 535-537
-
-
Lafoncazal, M.1
Pietri, S.2
Culcasi, M.3
Bockaert, J.4
-
134
-
-
0030298459
-
Cyclosporin a delays mitochondrial depolarization induced by N-methyl-D-aspaparte in cortical neurons: Evidence of the mitochondrial permeability transition
-
Nieminen AL, Petrie TG, Lemasters JJ, Selman WR (1996) Cyclosporin a delays mitochondrial depolarization induced by N-methyl-D-aspaparte in cortical neurons: Evidence of the mitochondrial permeability transition. Neuroscience 75, 993-997.
-
(1996)
Neuroscience
, vol.75
, pp. 993-997
-
-
Nieminen, A.L.1
Petrie, T.G.2
Lemasters, J.J.3
Selman, W.R.4
-
135
-
-
0030052530
-
Requirement for superoxide in excitotoxic cell death
-
Patel M, Day BJ, Crapo JD, Fridovich I, McNamara JO (1996) Requirement for superoxide in excitotoxic cell death. Neuron 16, 345-355.
-
(1996)
Neuron
, vol.16
, pp. 345-355
-
-
Patel, M.1
Day, B.J.2
Crapo, J.D.3
Fridovich, I.4
McNamara, J.O.5
-
136
-
-
0029064518
-
Glutamate induces the production ofreactive oxygen species in cultured forebrain neurons following NMDA receptor activation
-
Reynolds IJ, Hastings TG (1995) Glutamate induces the production ofreactive oxygen species in cultured forebrain neurons following NMDA receptor activation. J Neurosci 15, 3318-3327.
-
(1995)
J Neurosci
, vol.15
, pp. 3318-3327
-
-
Reynolds, I.J.1
Hastings, T.G.2
-
137
-
-
0029788243
-
Mitochondrial depolarization in glutamate-stimulated neurons: An early signal specific to excitotoxin exposure
-
White RJ, Reynolds IJ (1996) Mitochondrial depolarization in glutamate-stimulated neurons: An early signal specific to excitotoxin exposure. J Neurosci 16, 5688-5697.
-
(1996)
J Neurosci
, vol.16
, pp. 5688-5697
-
-
White, R.J.1
Reynolds, I.J.2
-
138
-
-
0022972426
-
Brain alpha-ketoglutarate dehydroge- nase complex: Kinetic properties, regional distribution, and effects of inhibitors
-
Lai J, Cooper A (1986) Brain alpha-ketoglutarate dehydroge- nase complex: kinetic properties, regional distribution, and effects of inhibitors. J Neurochem 47, 1376-1386.
-
(1986)
J Neurochem
, vol.47
, pp. 1376-1386
-
-
Lai, J.1
Cooper, A.2
-
140
-
-
33845451992
-
The effect of bovine serum albumin on the membrane potential and reactive oxygen species generation in succinate-supported isolated brain mitochondria
-
Tretter L, Mayer-Takacs D, Adam-Vizi V (2007) The effect of bovine serum albumin on the membrane potential and reactive oxygen species generation in succinate-supported isolated brain mitochondria. Neurochem Int 50, 139-147.
-
(2007)
Neurochem Int
, vol.50
, pp. 139-147
-
-
Tretter, L.1
Mayer-Takacs, D.2
Adam-Vizi, V.3
-
141
-
-
0042433242
-
2 production by membrane potential and NAD(P)H redox state
-
2 production by membrane potential and NAD(P)H redox state. J Neurochem 86, 1101-1107.
-
(2003)
J Neurochem
, vol.86
, pp. 1101-1107
-
-
Starkov, A.A.1
Fiskum, G.2
-
142
-
-
33947592809
-
Moderate dependence of ROS formation on Delta psi m in isolated brain mitochondria supported by NADH-linked substrates
-
Tretter L, Adam-Vizi V (2007) Moderate dependence of ROS formation on Delta psi m in isolated brain mitochondria supported by NADH-linked substrates. Neurochem Res 32, 569575.
-
(2007)
Neurochem Res
, vol.32
, pp. 569-575
-
-
Tretter, L.1
Adam-Vizi, V.2
-
143
-
-
77953808538
-
Membrane potential-related effect of calcium on reactive oxygen species generation in isolated brain mitochondria
-
in press
-
Komary Z, Tretter L, Adam-Vizi V (2010) Membrane potential-related effect of calcium on reactive oxygen species generation in isolated brain mitochondria. Biochim Biophys Acta, in press.
-
(2010)
Biochim Biophys Acta
-
-
Komary, Z.1
Tretter, L.2
Adam-Vizi, V.3
-
144
-
-
0034668844
-
Limitations of cy- closporin A inhibition of the permeability transition in CNS mitochondria
-
Brustovetsky N, Dubinsky JM (2000) Limitations of cy- closporin A inhibition of the permeability transition in CNS mitochondria. J Neurosci 20, 8229-8237.
-
(2000)
J Neurosci
, vol.20
, pp. 8229-8237
-
-
Brustovetsky, N.1
Dubinsky, J.M.2
-
145
-
-
0024271346
-
Kinetic evidence for a heart mi- tochondrial pore activated by Ca2+, inorganic-phosphate and oxidative stress - A potential mechanism fot mitochondrial dysfunction during cellular Ca2+ overload
-
Crompton M, Costi A (1988) Kinetic evidence for a heart mi- tochondrial pore activated by Ca2+, inorganic-phosphate and oxidative stress - a potential mechanism fot mitochondrial dysfunction during cellular Ca2+ overload. Eur J Biochem 178, 489-501.
-
(1988)
Eur J Biochem
, vol.178
, pp. 489-501
-
-
Crompton, M.1
Costi, A.2
-
146
-
-
0025193488
-
Inhibition of Ca2+- induced large-amplitude swelling of liver and heart- mitochondria by cyclosporine is probably caused by the inhibitor binding to mitochondrial-matrix peptidyl-prolyl cis-trans isomerase and preventing it interacting with the adenine-nucleotide translocase
-
Halestrap AP, Davidson AM (1990) Inhibition of Ca2+- induced large-amplitude swelling of liver and heart- mitochondria by cyclosporine is probably caused by the inhibitor binding to mitochondrial-matrix peptidyl-prolyl cis-trans isomerase and preventing it interacting with the adenine-nucleotide translocase. Biochem J 268, 153-160.
-
(1990)
Biochem J
, vol.268
, pp. 153-160
-
-
Halestrap, A.P.1
Davidson, A.M.2
-
147
-
-
0018332596
-
Ca2+-induced membrane transition in mitochondria. 1. protective mechanisms
-
Hunter DR, Haworth RA (1979) Ca2+-induced membrane transition in mitochondria. 1. protective mechanisms. Arch Biochem Biophys 195, 453-459.
-
(1979)
Arch Biochem Biophys
, vol.195
, pp. 453-459
-
-
Hunter, D.R.1
Haworth, R.A.2
-
148
-
-
0018367205
-
Effect of calcium on the translocation of adenine- nucleotides in rat-liver mitochondria
-
Gomezpuyou A, Tuenadegomezpuyou M, Klapp M, Carafoli E (1979) Effect of calcium on the translocation of adenine- nucleotides in rat-liver mitochondria. Arch Biochem Biophys 194, 399-404.
-
(1979)
Arch Biochem Biophys
, vol.194
, pp. 399-404
-
-
Gomezpuyou, A.1
Tuenadegomezpuyou, M.2
Klapp, M.3
Carafoli, E.4
-
149
-
-
0028985852
-
Inhibition by Ca2+ ofthe hydrolysis and the synthesis of ATP in ehrlich ascites tumor mitochondria - Relation to the crabtree effect
-
Bogucka K, Teplova VV, Wojtczaka L, Evtodienko YV (1995) Inhibition by Ca2+ ofthe hydrolysis and the synthesis of ATP in ehrlich ascites tumor mitochondria - relation to the crabtree effect. Biochim Biophys Acta 1228, 261-266.
-
(1995)
Biochim Biophys Acta
, vol.1228
, pp. 261-266
-
-
Bogucka, K.1
Teplova, V.V.2
Wojtczaka, L.3
Evtodienko, Y.V.4
-
150
-
-
0019316021
-
Control of activity states of heart mitochondrial ATPase role of the proton-motive force and Ca2+
-
Tuenadegomezpuyou M, Gavilanes M, Gomezpuyou A, Ern- ster L (1980) Control of activity states of heart mitochondrial ATPase role of the proton-motive force and Ca2+. Biochim Biophys Acta 592, 396-405.
-
(1980)
Biochim Biophys Acta
, vol.592
, pp. 396-405
-
-
Tuenadegomezpuyou, M.1
Gavilanes, M.2
Gomezpuyou, A.3
Ern- Ster, L.4
-
151
-
-
0032194957
-
Ca2+-stimulated mitochondrial reactive oxygen species generation and permeability transition are inhibited by dibucaine or Mg2+
-
Kowaltowski AJ, Naia-da-Silva ES, Castilho RF, Vercesi AE (1998) Ca2+-stimulated mitochondrial reactive oxygen species generation and permeability transition are inhibited by dibucaine or Mg2+. Arch Biochem Biophys 359, 77-81.
-
(1998)
Arch Biochem Biophys
, vol.359
, pp. 77-81
-
-
Kowaltowski, A.J.1
Naia-Da-Silva, E.S.2
Castilho, R.F.3
Vercesi, A.E.4
-
152
-
-
0035667431
-
Oxidative stress in Ca2+-induced membrane permeability transition in brain mitochondria
-
Maciel EN, Vercesi AE, Castilho RF (2001) Oxidative stress in Ca2+-induced membrane permeability transition in brain mitochondria. J Neurochem 79, 1237-1245.
-
(2001)
J Neurochem
, vol.79
, pp. 1237-1245
-
-
MacIel, E.N.1
Vercesi, A.E.2
Castilho, R.F.3
-
153
-
-
0035890197
-
Dynamics of intracellular calcium and free radical production during ischemia in pyramidal neurons
-
Frantseva MV, Carlen PL, Velazquez JLP (2001) Dynamics of intracellular calcium and free radical production during ischemia in pyramidal neurons. Free Radic Biol Med 31, 1216-1227.
-
(2001)
Free Radic Biol Med
, vol.31
, pp. 1216-1227
-
-
Frantseva, M.V.1
Carlen, P.L.2
Jlp, V.3
-
154
-
-
0035951823
-
Opening of the mitochondrial permeability transition pore causes depletion of mitochondrial and cytosolic NAD(+) and is a causative event in the death of myocytes in postischemic reperfusion of the heart
-
Di Lisa F, Menabo R, Canton M, Barile M, Bernardi P (2001) Opening of the mitochondrial permeability transition pore causes depletion of mitochondrial and cytosolic NAD(+) and is a causative event in the death of myocytes in postischemic reperfusion of the heart. J Biol Chem 276, 2571-2575.
-
(2001)
J Biol Chem
, vol.276
, pp. 2571-2575
-
-
Di Lisa, F.1
Menabo, R.2
Canton, M.3
Barile, M.4
Bernardi, P.5
-
155
-
-
35648950425
-
Calcium-sensitive regulation of monoamine oxidase-A contributes to the production of peroxyradicals in hippocampal cultures: Implications for Alzheimer disease-related pathology
-
Cao X, Wei ZL, Gabriel GG, Li XM, Mousseau DD (2007) Calcium-sensitive regulation of monoamine oxidase-A contributes to the production of peroxyradicals in hippocampal cultures: implications for Alzheimer disease-related pathology. BMC Neurosci 8, 10.
-
(2007)
BMC Neurosci
, vol.8
, pp. 10
-
-
Cao, X.1
Wei, Z.L.2
Gabriel, G.G.3
Li, X.M.4
Mousseau, D.D.5
-
156
-
-
0036313070
-
The effects of focal ischemia and reperfusion on the glutathione content of mitochondria from rat brain subregions
-
Anderson MF, Sims NR (2002) The effects of focal ischemia and reperfusion on the glutathione content of mitochondria from rat brain subregions. J Neurochem 81, 541-549.
-
(2002)
J Neurochem
, vol.81
, pp. 541-549
-
-
Anderson, M.F.1
Sims, N.R.2
-
158
-
-
47549096022
-
Superoxide flashes in single mitochondria
-
Wang W, Fang H, Groom L, Cheng A, Zhang W, Liu J, Wang X, Li K, Han P, Zheng M, Yin J, Mattson MP, Kao JP, Lakatta EG, Sheu SS, Ouyang K, Chen J, Dirksen RT, Cheng H (2008) Superoxide flashes in single mitochondria. Cell 134, 279-290.
-
(2008)
Cell
, vol.134
, pp. 279-290
-
-
Wang, W.1
Fang, H.2
Groom, L.3
Cheng, A.4
Zhang, W.5
Liu, J.6
Wang, X.7
Li, K.8
Han, P.9
Zheng, M.10
Yin, J.11
Mattson, M.P.12
Kao, J.P.13
Lakatta, E.G.14
Sheu, S.S.15
Ouyang, K.16
Chen, J.17
Dirksen, R.T.18
Cheng, H.19
-
159
-
-
0035780141
-
Amyloid beta-peptide promotes permeability transition pore in brain mitochondria
-
Moreira PI, Santos MS, Moreno A, Oliveira C (2001) Amyloid beta-peptide promotes permeability transition pore in brain mitochondria. Biosci Rep 21, 789-800.
-
(2001)
Biosci Rep
, vol.21
, pp. 789-800
-
-
Moreira, P.I.1
Santos, M.S.2
Moreno, A.3
Oliveira, C.4
-
160
-
-
0037100213
-
Effect of amyloid beta-peptide on permeability transition pore: A comparative study
-
Moreira PI, Santos MS, Moreno A, Rego AC, Oliveira C (2002) Effect of amyloid beta-peptide on permeability transition pore: A comparative study. J Neurosci Res 69, 257-267.
-
(2002)
J Neurosci Res
, vol.69
, pp. 257-267
-
-
Moreira, P.I.1
Santos, M.S.2
Moreno, A.3
Rego, A.C.4
Oliveira, C.5
-
161
-
-
0037191378
-
Amyloid beta peptide induces cytochrome c release from isolated mitochondria
-
Kim HS, Lee JH, Lee JP, Kim EM, Chang KA, Park CH, Jeong SJ, Wittendorp MC, Seo JH, Choi SH, Suh YH (2002) Amyloid beta peptide induces cytochrome c release from isolated mitochondria. Neuroreport 13, 1989-1993.
-
(2002)
Neuroreport
, vol.13
, pp. 1989-1993
-
-
Kim, H.S.1
Lee, J.H.2
Lee, J.P.3
Kim, E.M.4
Chang, K.A.5
Park, C.H.6
Jeong, S.J.7
Wittendorp, M.C.8
Seo, J.H.9
Choi, S.H.10
Suh, Y.H.11
-
162
-
-
0036258363
-
Effect of beta-amyloid peptide fragment 25-35 on nonselective permeability of mitochondria
-
Shevtzova EF, Kireeva EG, Bachurin SO (2001) Effect of beta-amyloid peptide fragment 25-35 on nonselective permeability of mitochondria. Bull Exp Biol Med 132, 1173-1176.
-
(2001)
Bull Exp Biol Med
, vol.132
, pp. 1173-1176
-
-
Shevtzova, E.F.1
Kireeva, E.G.2
Bachurin, S.O.3
-
163
-
-
50549096439
-
Mitochondrial Ca2+ overload underlies a beta oligomers neurotoxicity providing an unexpected mechanism of neuroprotection by NSAIDs
-
Sanz-Blasco S, Valero RA, Rodriguez-Crespo I, Villalobos C, Nunez L (2008) Mitochondrial Ca2+ overload underlies a beta oligomers neurotoxicity providing an unexpected mechanism of neuroprotection by NSAIDs. PLoS ONE 3, 16.
-
(2008)
PLoS ONE
, vol.3
, pp. 16
-
-
Sanz-Blasco, S.1
Valero, R.A.2
Rodriguez-Crespo, I.3
Villalobos, C.4
Nunez, L.5
-
164
-
-
33847662852
-
Soluble protein oligomers in neurodegeneration: Lessons from the Alzheimer's amyloid beta-peptide
-
Haass C, Selkoe DJ (2007) Soluble protein oligomers in neurodegeneration: lessons from the Alzheimer's amyloid beta-peptide. NatRevMol Cell Biol 8, 101-112.
-
(2007)
NatRevMol Cell Biol
, vol.8
, pp. 101-112
-
-
Haass, C.1
Selkoe, D.J.2
-
165
-
-
53549129483
-
Cyclophilin D deficiency attenuates mitochondrial and neu- ronal perturbation and ameliorates learning and memory in Alzheimer's disease
-
Du H, Guo L, Fang F, Chen D, Sosunov AA, McKhann GM, Yan YL, Wang CY, Zhang H, Molkentin JD, Gunn-Moore FJ, Vonsattel JP, Arancio O, Chen JX, Du Yan S (2008) Cyclophilin D deficiency attenuates mitochondrial and neu- ronal perturbation and ameliorates learning and memory in Alzheimer's disease. Nat Med 14, 1097-1105.
-
(2008)
Nat Med
, vol.14
, pp. 1097-1105
-
-
Du, H.1
Guo, L.2
Fang, F.3
Chen, D.4
Sosunov, A.A.5
McKhann, G.M.6
Yan, Y.L.7
Wang, C.Y.8
Zhang, H.9
Molkentin, J.D.10
Gunn-Moore, F.J.11
Vonsattel, J.P.12
Arancio, O.13
Chen, J.X.14
Du Yan, S.15
-
166
-
-
0024235934
-
Pyruvate- dehydrogenase complex is inhibited in calcium-loaded cere- brocortical mitochondria
-
Lai JCK, Dilorenzo JC, Sheu KFR (1988) Pyruvate- dehydrogenase complex is inhibited in calcium-loaded cere- brocortical mitochondria. Neurochem Res 13, 1043-1048.
-
(1988)
Neurochem Res
, vol.13
, pp. 1043-1048
-
-
Jck, L.1
Dilorenzo, J.C.2
Kfr, S.3
-
167
-
-
0019469676
-
The interaction of calcium-transport and ADP phosphorylation in brain mitochondria
-
Roman I, Clark A, Swanson PD (1981) The interaction of calcium-transport and ADP phosphorylation in brain mitochondria. Membrane Biochem 4, 1-9.
-
(1981)
Membrane Biochem
, vol.4
, pp. 1-9
-
-
Roman, I.1
Clark, A.2
Swanson, P.D.3
-
168
-
-
0019332352
-
Inhibition of oxidative- phosphorylation in ascites tumor mitochondria and cells by intra-mitochondrial Ca2+
-
Villalobo A, Lehninger AL (1980) Inhibition of oxidative- phosphorylation in ascites tumor mitochondria and cells by intra-mitochondrial Ca2+. J Biol Chem 255, 2457-2464.
-
(1980)
J Biol Chem
, vol.255
, pp. 2457-2464
-
-
Villalobo, A.1
Lehninger, A.L.2
-
169
-
-
0038143180
-
The relationship between free and total calcium concentrations in the matrix of liver and brain mitochondria
-
Chalmers S, Nicholls DG (2003) The relationship between free and total calcium concentrations in the matrix of liver and brain mitochondria. J Biol Chem 278, 19062-19070.
-
(2003)
J Biol Chem
, vol.278
, pp. 19062-19070
-
-
Chalmers, S.1
Nicholls, D.G.2
-
170
-
-
0242684750
-
Heterogeneity of the calcium-induced permeability transition in isolated non-synaptic brain mitochondria
-
Kristian T, Weatherby TM, Bates TE, Fiskum G (2002) Heterogeneity of the calcium-induced permeability transition in isolated non-synaptic brain mitochondria. J Neurochem 83, 1297-1308.
-
(2002)
J Neurochem
, vol.83
, pp. 1297-1308
-
-
Kristian, T.1
Weatherby, T.M.2
Bates, T.E.3
Fiskum, G.4
-
171
-
-
0037891050
-
Cyclosporin A-insensitive permeability transition in brain mitochondria - Inhibition by 2-aminoethoxydiphenyl borate
-
Chinopoulos C, Starkov AA, Fiskum G (2003) Cyclosporin A-insensitive permeability transition in brain mitochondria - Inhibition by 2-aminoethoxydiphenyl borate. J Biol Chem 278, 27382-27389.
-
(2003)
J Biol Chem
, vol.278
, pp. 27382-27389
-
-
Chinopoulos, C.1
Starkov, A.A.2
Fiskum, G.3
|