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Volumn 29, Issue 3, 2010, Pages 405-434

Regulation of survival, proliferation, invasion, angiogenesis, and metastasis of tumor cells through modulation of inflammatory pathways by nutraceuticals

Author keywords

Inflammation; NF B; Nutraceuticals; Therapeutics; Tumorigenesis

Indexed keywords

3 INDOLEMETHANOL; ALLICIN; ANACARDIC ACID; APIGENIN; BERBERINE; BUTEIN; CAFFEIC ACID; CAPSAICIN; CELASTROL; CURCUMIN; EPICATECHIN GALLATE; EPIGALLOCATECHIN GALLATE; EVODIAMINE; FISETIN; FLAVOPIRIDOL; GAMBOGIC ACID; GAMMA TOCOTRIENOL; GENISTEIN; GUGGULSTERONE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; NUTRACEUTICAL; PACLITAXEL; PLUMBAGIN; QUERCETIN; RESVERATROL; SANGUINARINE; SILIBININ; SULFORAPHANE; TURMERIC; UNINDEXED DRUG;

EID: 77957592789     PISSN: 01677659     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10555-010-9235-2     Document Type: Review
Times cited : (682)

References (280)
  • 1
    • 0034614637 scopus 로고    scopus 로고
    • The hallmarks of cancer
    • 1:CAS:528:DC%2BD3cXks1CktA%3D%3D 10647931 10.1016/S0092-8674(00)81683-9
    • D Hanahan RA Weinberg 2000 The hallmarks of cancer Cell 100 57 70 1:CAS:528:DC%2BD3cXks1CktA%3D%3D 10647931 10.1016/S0092-8674(00)81683-9
    • (2000) Cell , vol.100 , pp. 57-70
    • Hanahan, D.1    Weinberg, R.A.2
  • 2
    • 68149145788 scopus 로고    scopus 로고
    • Molecular targets of nutraceuticals derived from dietary spices: Potential role in suppression of inflammation and tumorigenesis
    • 1:CAS:528:DC%2BD1MXpt1WksLw%3D 10.3181/0902-MR-78
    • BB Aggarwal ME Van Kuiken LH Iyer KB Harikumar B Sung 2009 Molecular targets of nutraceuticals derived from dietary spices: Potential role in suppression of inflammation and tumorigenesis Experimental Biology and Medicine (Maywood, N.J) 234 825 849 1:CAS:528:DC%2BD1MXpt1WksLw%3D 10.3181/0902-MR-78
    • (2009) Experimental Biology and Medicine (Maywood, N.J) , vol.234 , pp. 825-849
    • Aggarwal, B.B.1    Van Kuiken, M.E.2    Iyer, L.H.3    Harikumar, K.B.4    Sung, B.5
  • 3
    • 0027360855 scopus 로고
    • Actual causes of death in the United States
    • DOI 10.1001/jama.270.18.2207
    • JM McGinnis WH Foege 1993 Actual causes of death in the United States JAMA 270 2207 2212 1:STN:280:DyaK2c%2FhslWgtA%3D%3D 8411605 10.1001/jama.270.18. 2207 (Pubitemid 23323637)
    • (1993) Journal of the American Medical Association , vol.270 , Issue.18 , pp. 2207-2212
    • McGinnis, J.M.1    Foege, W.H.2
  • 4
    • 0037864005 scopus 로고    scopus 로고
    • Natural products for cancer prevention: A global perspective
    • DOI 10.1016/S0163-7258(03)00042-1
    • L Reddy B Odhav KD Bhoola 2003 Natural products for cancer prevention: A global perspective Pharmacology & Therapeutics 99 1 13 1:CAS:528: DC%2BD3sXksVehu7Y%3D 10.1016/S0163-7258(03)00042-1 (Pubitemid 36694746)
    • (2003) Pharmacology and Therapeutics , vol.99 , Issue.1 , pp. 1-13
    • Reddy, L.1    Odhav, B.2    Bhoola, K.D.3
  • 5
    • 0026701521 scopus 로고
    • Fruit, vegetables, and cancer prevention: A review of the epidemiological evidence
    • 1:STN:280:DyaK3s%2FislGnsQ%3D%3D 1408943 10.1080/01635589209514201
    • G Block B Patterson A Subar 1992 Fruit, vegetables, and cancer prevention: A review of the epidemiological evidence Nutrition and Cancer 18 1 29 1:STN:280:DyaK3s%2FislGnsQ%3D%3D 1408943 10.1080/01635589209514201
    • (1992) Nutrition and Cancer , vol.18 , pp. 1-29
    • Block, G.1    Patterson, B.2    Subar, A.3
  • 6
    • 39449098356 scopus 로고    scopus 로고
    • Vegetables and fruits in relation to cancer risk: Evidence from the Greek EPIC cohort study
    • DOI 10.1158/1055-9965.EPI-07-2665
    • V Benetou P Orfanos P Lagiou D Trichopoulos P Boffetta A Trichopoulou 2008 Vegetables and fruits in relation to cancer risk: Evidence from the Greek EPIC cohort study Cancer Epidemiology, Biomarkers & Prevention 17 387 392 1:CAS:528:DC%2BD1cXhslaru7o%3D 10.1158/1055-9965.EPI-07-2665 (Pubitemid 351272791)
    • (2008) Cancer Epidemiology Biomarkers and Prevention , vol.17 , Issue.2 , pp. 387-392
    • Benetou, V.1    Orfanos, P.2    Lagiou, P.3    Trichopoulos, D.4    Boffetta, P.5    Trichopoulou, A.6
  • 7
    • 42149180471 scopus 로고    scopus 로고
    • Fruit and vegetable intake and head and neck cancer risk in a large United States prospective cohort study
    • DOI 10.1002/ijc.23319
    • ND Freedman Y Park AF Subar AR Hollenbeck MF Leitzmann A Schatzkin, et al. 2008 Fruit and vegetable intake and head and neck cancer risk in a large United States prospective cohort study International Journal of Cancer 122 2330 2336 1:CAS:528:DC%2BD1cXkslynt7g%3D 10.1002/ijc.23319 (Pubitemid 351542339)
    • (2008) International Journal of Cancer , vol.122 , Issue.10 , pp. 2330-2336
    • Freedman, N.D.1    Park, Y.2    Subar, A.F.3    Hollenbeck, A.R.4    Leitzmann, M.F.5    Schatzkin, A.6    Abnet, C.C.7
  • 8
    • 0030411296 scopus 로고    scopus 로고
    • Vegetables, fruit, and cancer prevention: A review
    • DOI 10.1016/S0002-8223(96)00273-8
    • KA Steinmetz JD Potter 1996 Vegetables, fruit, and cancer prevention: A review Journal of the American Dietetic Association 96 1027 1039 1:STN:280:DyaK28vjvVygsg%3D%3D 8841165 10.1016/S0002-8223(96)00273-8 (Pubitemid 27382158)
    • (1996) Journal of the American Dietetic Association , vol.96 , Issue.10 , pp. 1027-1039
    • Steinmetz, K.A.1    Potter, J.D.2
  • 9
    • 0019829568 scopus 로고
    • The causes of cancer: Quantitative estimates of avoidable risks of cancer in the United States today
    • 1:STN:280:DyaL3M3hvFShsA%3D%3D 7017215
    • R Doll R Peto 1981 The causes of cancer: Quantitative estimates of avoidable risks of cancer in the United States today Journal of the National Cancer Institute 66 1191 1308 1:STN:280:DyaL3M3hvFShsA%3D%3D 7017215
    • (1981) Journal of the National Cancer Institute , vol.66 , pp. 1191-1308
    • Doll, R.1    Peto, R.2
  • 10
    • 2442597325 scopus 로고    scopus 로고
    • Nutraceuticals - A pharmaceutical viewpoint: Part II
    • DOI 10.1097/00075197-200311000-00010
    • G Hardy I Hardy PA Ball 2003 Nutraceuticals-A pharmaceutical viewpoint: Part II Current Opinion in Clinical Nutrition and Metabolic Care 6 661 671 1:CAS:528:DC%2BD3sXpsFChurs%3D 14557798 10.1097/00075197-200311000-00010 (Pubitemid 40674515)
    • (2003) Current Opinion in Clinical Nutrition and Metabolic Care , vol.6 , Issue.6 , pp. 661-671
    • Hardy, G.1    Hardy, I.2    Ball, P.A.3
  • 11
    • 77951630296 scopus 로고    scopus 로고
    • Primary prevention of colorectal cancer
    • AT Chan EL Giovannucci 2010 Primary prevention of colorectal cancer Gastroenterology 138 2029.e10 2043.e10
    • (2010) Gastroenterology , vol.138
    • Chan, A.T.1    Giovannucci, E.L.2
  • 12
    • 38349000628 scopus 로고    scopus 로고
    • Cancer chemoprevention through dietary antioxidants: Progress and promise
    • 1:CAS:528:DC%2BD1cXmt1yluw%3D%3D 18154485 10.1089/ars.2007.1740
    • N Khan F Afaq H Mukhtar 2008 Cancer chemoprevention through dietary antioxidants: Progress and promise Antioxidants Redox Signaling 10 475 510 1:CAS:528:DC%2BD1cXmt1yluw%3D%3D 18154485 10.1089/ars.2007.1740
    • (2008) Antioxidants Redox Signaling , vol.10 , pp. 475-510
    • Khan, N.1    Afaq, F.2    Mukhtar, H.3
  • 13
    • 43949121393 scopus 로고    scopus 로고
    • Dietary agents for chemoprevention of prostate cancer
    • 1:CAS:528:DC%2BD1cXmtlWhsLw%3D 18395333 10.1016/j.canlet.2008.02.050
    • DN Syed Y Suh F Afaq H Mukhtar 2008 Dietary agents for chemoprevention of prostate cancer Cancer Letters 265 167 176 1:CAS:528:DC%2BD1cXmtlWhsLw%3D 18395333 10.1016/j.canlet.2008.02.050
    • (2008) Cancer Letters , vol.265 , pp. 167-176
    • Syed, D.N.1    Suh, Y.2    Afaq, F.3    Mukhtar, H.4
  • 14
    • 70649092373 scopus 로고    scopus 로고
    • Is there a benefit from lycopene supplementation in men with prostate cancer? A systematic review
    • 1:CAS:528:DC%2BD1MXhtl2iurnP 19901932 10.1038/pcan.2009.38
    • F Haseen MM Cantwell JM O'Sullivan LJ Murray 2009 Is there a benefit from lycopene supplementation in men with prostate cancer? A systematic review Prostate Cancer and Prostatic Diseases 12 325 332 1:CAS:528:DC%2BD1MXhtl2iurnP 19901932 10.1038/pcan.2009.38
    • (2009) Prostate Cancer and Prostatic Diseases , vol.12 , pp. 325-332
    • Haseen, F.1    Cantwell, M.M.2    O'Sullivan, J.M.3    Murray, L.J.4
  • 15
    • 71749106273 scopus 로고    scopus 로고
    • Fatty acids and breast cancer: Sensitization to treatments and prevention of metastatic re-growth
    • 1:CAS:528:DC%2BD1MXhsFykt7vL 19715726 10.1016/j.plipres.2009.08.003
    • P Bougnoux N Hajjaji K Maheo C Couet S Chevalier 2010 Fatty acids and breast cancer: Sensitization to treatments and prevention of metastatic re-growth Progress in Lipid Research 49 76 86 1:CAS:528:DC%2BD1MXhsFykt7vL 19715726 10.1016/j.plipres.2009.08.003
    • (2010) Progress in Lipid Research , vol.49 , pp. 76-86
    • Bougnoux, P.1    Hajjaji, N.2    Maheo, K.3    Couet, C.4    Chevalier, S.5
  • 16
    • 74549116464 scopus 로고    scopus 로고
    • Nutrition aspects of lung cancer
    • 19955546 10.1177/0884533609352249
    • A Cranganu J Camporeale 2009 Nutrition aspects of lung cancer Nutrition in Clinical Practice 24 688 700 19955546 10.1177/0884533609352249
    • (2009) Nutrition in Clinical Practice , vol.24 , pp. 688-700
    • Cranganu, A.1    Camporeale, J.2
  • 17
    • 77952486784 scopus 로고    scopus 로고
    • Beta-carotene and lung cancer in smokers: Review of hypotheses and status of research
    • 1:CAS:528:DC%2BC3cXjsVOgsw%3D%3D 20155614 10.1080/01635580903285155
    • R Goralczyk 2009 Beta-carotene and lung cancer in smokers: Review of hypotheses and status of research Nutrition and Cancer 61 767 774 1:CAS:528:DC%2BC3cXjsVOgsw%3D%3D 20155614 10.1080/01635580903285155
    • (2009) Nutrition and Cancer , vol.61 , pp. 767-774
    • Goralczyk, R.1
  • 19
    • 45849149639 scopus 로고    scopus 로고
    • Curcumin and cancer: An "old-age" disease with an "age-old" solution
    • 1:CAS:528:DC%2BD1cXotlCgtbs%3D 18462866 10.1016/j.canlet.2008.03.025
    • P Anand C Sundaram S Jhurani AB Kunnumakkara BB Aggarwal 2008 Curcumin and cancer: An "old-age" disease with an "age-old" solution Cancer Letters 267 133 164 1:CAS:528:DC%2BD1cXotlCgtbs%3D 18462866 10.1016/j.canlet.2008.03.025
    • (2008) Cancer Letters , vol.267 , pp. 133-164
    • Anand, P.1    Sundaram, C.2    Jhurani, S.3    Kunnumakkara, A.B.4    Aggarwal, B.B.5
  • 20
    • 4043181214 scopus 로고    scopus 로고
    • Cancer genes and the pathways they control
    • DOI 10.1038/nm1087
    • B Vogelstein KW Kinzler 2004 Cancer genes and the pathways they control Nature Medicine 10 789 799 1:CAS:528:DC%2BD2cXmtFWrt7o%3D 15286780 10.1038/nm1087 (Pubitemid 39070849)
    • (2004) Nature Medicine , vol.10 , Issue.8 , pp. 789-799
    • Vogelstein, B.1    Kinzler, K.W.2
  • 21
    • 66849095259 scopus 로고    scopus 로고
    • Perspectives for cancer prevention with natural compounds
    • 19414669 10.1200/JCO.2008.20.6235 1:CAS:528:DC%2BD1MXnslWitLg%3D
    • AR Amin O Kucuk FR Khuri DM Shin 2009 Perspectives for cancer prevention with natural compounds Journal of Clinical Oncology 27 2712 2725 19414669 10.1200/JCO.2008.20.6235 1:CAS:528:DC%2BD1MXnslWitLg%3D
    • (2009) Journal of Clinical Oncology , vol.27 , pp. 2712-2725
    • Amin, A.R.1    Kucuk, O.2    Khuri, F.R.3    Shin, D.M.4
  • 22
    • 50149095987 scopus 로고    scopus 로고
    • Diet and cancer prevention: The roles of observation and experimentation
    • 1:CAS:528:DC%2BD1cXhtVWksb7E 19143054 10.1038/nrc2441
    • ME Martinez JR Marshall E Giovannucci 2008 Diet and cancer prevention: The roles of observation and experimentation Nature Reviews. Cancer 8 694 703 1:CAS:528:DC%2BD1cXhtVWksb7E 19143054 10.1038/nrc2441
    • (2008) Nature Reviews. Cancer , vol.8 , pp. 694-703
    • Martinez, M.E.1    Marshall, J.R.2    Giovannucci, E.3
  • 23
    • 0031928015 scopus 로고    scopus 로고
    • Nutraceuticals: Poised for a healthy slice of the healthcare market?
    • DOI 10.1038/nbt0898-728
    • V Brower 1998 Nutraceuticals: Poised for a healthy slice of the healthcare market? Nature Biotechnology 16 728 731 1:CAS:528:DyaK1cXltV2qsbo%3D 9702769 10.1038/nbt0898-728 (Pubitemid 28363752)
    • (1998) Nature Biotechnology , vol.16 , Issue.8 , pp. 728-730
    • Brower, V.1
  • 24
    • 0033578922 scopus 로고    scopus 로고
    • Regulation of 'nutraceuticals'
    • DOI 10.1126/science.285.5435.1853
    • SH Zeisel 1999 Regulation of "nutraceuticals" Science 285 1853 1855 1:CAS:528:DyaK1MXmtVCntrg%3D 10515789 10.1126/science.285.5435.1853 (Pubitemid 29444598)
    • (1999) Science , vol.285 , Issue.5435 , pp. 1853-1855
    • Zeisel, S.H.1
  • 25
    • 0346039322 scopus 로고    scopus 로고
    • Nutraceutical-Definition and introduction
    • 14621960 10.1208/ps050325
    • EK Kalra 2003 Nutraceutical-Definition and introduction AAPS PharmSci 5 E25 14621960 10.1208/ps050325
    • (2003) AAPS PharmSci , vol.5 , pp. 25
    • Kalra, E.K.1
  • 26
    • 68849108869 scopus 로고    scopus 로고
    • Inflammation and cancer: How friendly is the relationship for cancer patients?
    • 1:CAS:528:DC%2BD1MXhtVenurnI 19665429 10.1016/j.coph.2009.06.020
    • BB Aggarwal P Gehlot 2009 Inflammation and cancer: How friendly is the relationship for cancer patients? Current Opinion in Pharmacology 9 351 369 1:CAS:528:DC%2BD1MXhtVenurnI 19665429 10.1016/j.coph.2009.06.020
    • (2009) Current Opinion in Pharmacology , vol.9 , pp. 351-369
    • Aggarwal, B.B.1    Gehlot, P.2
  • 27
    • 0028418695 scopus 로고
    • The Rel family of proteins in oncogenesis and differentiation
    • 1:CAS:528:DyaK2cXltVCnsr0%3D 8061327
    • N Kabrun PJ Enrietto 1994 The Rel family of proteins in oncogenesis and differentiation Seminars in Cancer Biology 5 103 112 1:CAS:528: DyaK2cXltVCnsr0%3D 8061327
    • (1994) Seminars in Cancer Biology , vol.5 , pp. 103-112
    • Kabrun, N.1    Enrietto, P.J.2
  • 28
    • 0036234459 scopus 로고    scopus 로고
    • Missing pieces in the NF-κB puzzle
    • DOI 10.1016/S0092-8674(02)00703-1
    • S Ghosh M Karin 2002 Missing pieces in the NF-kappaB puzzle Cell 109 Suppl S81 S96 1:CAS:528:DC%2BD38Xjt1equr4%3D 11983155 10.1016/S0092-8674(02) 00703-1 (Pubitemid 34457854)
    • (2002) Cell , vol.109 , Issue.2 SUPPL. 1
    • Ghosh, S.1    Karin, M.2
  • 30
    • 0033613436 scopus 로고    scopus 로고
    • Inhibition of cyclo-oxygenase 2 expression in colon cells by the chemopreventive agent curcumin involves inhibition of NF-κB activation via the NIK/IKK signalling complex
    • DOI 10.1038/sj.onc.1202980
    • SM Plummer KA Holloway MM Manson RJ Munks A Kaptein S Farrow, et al. 1999 Inhibition of cyclo-oxygenase 2 expression in colon cells by the chemopreventive agent curcumin involves inhibition of NF-kappaB activation via the NIK/IKK signalling complex Oncogene 18 6013 6020 1:CAS:528: DyaK1MXntlGitb8%3D 10557090 10.1038/sj.onc.1202980 (Pubitemid 29535013)
    • (1999) Oncogene , vol.18 , Issue.44 , pp. 6013-6020
    • Plummer, S.M.1    Holloway, K.A.2    Manson, M.M.3    Munks, R.J.L.4    Kaptein, A.5    Farrow, S.6    Howells, L.7
  • 31
    • 0028867742 scopus 로고
    • Activation of transcription factor NF-kappa B is suppressed by curcumin (diferuloylmethane) [corrected]
    • 1:CAS:528:DyaK2MXovFWmsb8%3D 7559628 10.1074/jbc.270.25.14867
    • S Singh BB Aggarwal 1995 Activation of transcription factor NF-kappa B is suppressed by curcumin (diferuloylmethane) [corrected] The Journal of Biological Chemistry 270 24995 25000 1:CAS:528:DyaK2MXovFWmsb8%3D 7559628 10.1074/jbc.270.25.14867
    • (1995) The Journal of Biological Chemistry , vol.270 , pp. 24995-25000
    • Singh, S.1    Aggarwal, B.B.2
  • 32
    • 0037305821 scopus 로고    scopus 로고
    • Curcumin (diferuloylmethane) down-regulates the constitutive activation of nuclear factor-κB and IκBα kinase in human multiple myeloma cells, leading to suppression of proliferation and induction of apoptosis
    • DOI 10.1182/blood-2002-05-1320
    • AC Bharti N Donato S Singh BB Aggarwal 2003 Curcumin (diferuloylmethane) down-regulates the constitutive activation of nuclear factor-kappa B and IkappaBalpha kinase in human multiple myeloma cells, leading to suppression of proliferation and induction of apoptosis Blood 101 1053 1062 1:CAS:528:DC%2BD3sXptVCisg%3D%3D 12393461 10.1182/blood-2002-05-1320 (Pubitemid 36139379)
    • (2003) Blood , vol.101 , Issue.3 , pp. 1053-1062
    • Bharti, A.C.1    Donato, N.2    Singh, S.3    Aggarwal, B.B.4
  • 33
    • 0038191064 scopus 로고    scopus 로고
    • Osteopontin induces nuclear factor κB-mediated promatrix metalloproteinase-2 activation through IκBα/IKK signaling pathways, and curcumin (diferulolylmethane) down-regulates these pathways
    • DOI 10.1074/jbc.M207309200
    • S Philip GC Kundu 2003 Osteopontin induces nuclear factor kappa B-mediated promatrix metalloproteinase-2 activation through I kappa B alpha/IKK signaling pathways, and curcumin (diferuloylmethane) down-regulates these pathways The Journal of Biological Chemistry 278 14487 14497 1:CAS:528:DC%2BD3sXjtVShtr8%3D 12473670 10.1074/jbc.M207309200 (Pubitemid 36800002)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.16 , pp. 14487-14497
    • Philip, S.1    Kundu, G.C.2
  • 34
    • 70249136561 scopus 로고    scopus 로고
    • Curcumin sensitizes human colorectal cancer to capecitabine by modulation of cyclin D1, COX-2, MMP-9, VEGF and CXCR4 expression in an orthotopic mouse model
    • 1:CAS:528:DC%2BD1MXhtVOms7vK 10.1002/ijc.24593
    • AB Kunnumakkara P Diagaradjane P Anand KB Harikumar A Deorukhkar J Gelovani, et al. 2009 Curcumin sensitizes human colorectal cancer to capecitabine by modulation of cyclin D1, COX-2, MMP-9, VEGF and CXCR4 expression in an orthotopic mouse model International Journal of Cancer 125 2187 2197 1:CAS:528:DC%2BD1MXhtVOms7vK 10.1002/ijc.24593
    • (2009) International Journal of Cancer , vol.125 , pp. 2187-2197
    • Kunnumakkara, A.B.1    Diagaradjane, P.2    Anand, P.3    Harikumar, K.B.4    Deorukhkar, A.5    Gelovani, J.6
  • 35
    • 8744234076 scopus 로고    scopus 로고
    • Guggulsterone inhibits NF-κB and IκBα kinase activation, suppresses expression of anti-apoptotic gene products, and enhances apoptosis
    • DOI 10.1074/jbc.M408093200
    • S Shishodia BB Aggarwal 2004 Guggulsterone inhibits NF-kappaB and IkappaBalpha kinase activation, suppresses expression of anti-apoptotic gene products, and enhances apoptosis The Journal of Biological Chemistry 279 47148 47158 1:CAS:528:DC%2BD2cXptFejsbc%3D 15322087 10.1074/jbc.M408093200 (Pubitemid 39518371)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.45 , pp. 47148-47158
    • Shishodia, S.1    Aggarwal, B.B.2
  • 36
    • 0037051715 scopus 로고    scopus 로고
    • Food-derived polyphenols inhibit pancreatic cancer growth through mitochondrial cytochrome c release and apoptosis
    • DOI 10.1002/ijc.10202
    • M Mouria AS Gukovskaya Y Jung P Buechler OJ Hines HA Reber, et al. 2002 Food-derived polyphenols inhibit pancreatic cancer growth through mitochondrial cytochrome C release and apoptosis International Journal of Cancer 98 761 769 1:CAS:528:DC%2BD38Xis1Wru7Y%3D 10.1002/ijc.10202 (Pubitemid 34225629)
    • (2002) International Journal of Cancer , vol.98 , Issue.5 , pp. 761-769
    • Mouria, M.1    Gukovskaya, A.S.2    Jung, Y.3    Buechler, P.4    Hines, O.J.5    Reber, H.A.6    Pandol, S.J.7
  • 37
    • 0036733776 scopus 로고    scopus 로고
    • Suppression of 7,12-dimethylbenz(a)anthracene-induced mammary carcinogenesis in rats by resveratrol: Role of nuclear factor-kappaB, cyclooxygenase 2, and matrix metalloprotease 9
    • 1:CAS:528:DC%2BD38Xmslylu7s%3D 12208745
    • S Banerjee C Bueso-Ramos BB Aggarwal 2002 Suppression of 7,12-dimethylbenz(a)anthracene-induced mammary carcinogenesis in rats by resveratrol: Role of nuclear factor-kappaB, cyclooxygenase 2, and matrix metalloprotease 9 Cancer Research 62 4945 4954 1:CAS:528:DC%2BD38Xmslylu7s%3D 12208745
    • (2002) Cancer Research , vol.62 , pp. 4945-4954
    • Banerjee, S.1    Bueso-Ramos, C.2    Aggarwal, B.B.3
  • 38
    • 15044361086 scopus 로고    scopus 로고
    • Suppression of the nuclear factor-κB activation pathway by spice-derived phytochemicals: Reasoning for seasoning
    • DOI 10.1196/annals.1329.054
    • BB Aggarwal S Shishodia 2004 Suppression of the nuclear factor-kappaB activation pathway by spice-derived phytochemicals: Reasoning for seasoning Annals of the New York Academy of Sciences 1030 434 441 1:CAS:528: DC%2BD2MXivFKrsLY%3D 15659827 10.1196/annals.1329.054 (Pubitemid 40378943)
    • (2004) Annals of the New York Academy of Sciences , vol.1030 , pp. 434-441
    • Aggarwal, B.B.1    Shishodia, S.2
  • 39
    • 0028913539 scopus 로고
    • Capsaicin, a double-edged sword: Toxicity, metabolism, and chemopreventive potential
    • 1:CAS:528:DyaK2MXlt1Wkuro%3D 7746093 10.1016/0024-3205(95)00159-4
    • YJ Surh SS Lee 1995 Capsaicin, a double-edged sword: Toxicity, metabolism, and chemopreventive potential Life Sciences 56 1845 1855 1:CAS:528:DyaK2MXlt1Wkuro%3D 7746093 10.1016/0024-3205(95)00159-4
    • (1995) Life Sciences , vol.56 , pp. 1845-1855
    • Surh, Y.J.1    Lee, S.S.2
  • 40
    • 0029928940 scopus 로고    scopus 로고
    • Capsaicin in hot chili pepper: Carcinogen, co-carcinogen or anticarcinogen?
    • DOI 10.1016/0278-6915(95)00108-5
    • YJ Surh SS Lee 1996 Capsaicin in hot chili pepper: Carcinogen, co-carcinogen or anticarcinogen? Food and Chemical Toxicology 34 313 316 1:CAS:528:DyaK28XhvFKmtrg%3D 8621114 10.1016/0278-6915(95)00108-5 (Pubitemid 26103448)
    • (1996) Food and Chemical Toxicology , vol.34 , Issue.3 , pp. 313-316
    • Surh, Y.-J.1    Lee, S.S.2
  • 41
    • 0028862921 scopus 로고
    • Chemoprotective effects of capsaicin and diallyl sulfide against mutagenesis or tumorigenesis by vinyl carbamate and N-nitrosodimethylamine
    • 1:CAS:528:DyaK2MXovFyrsr4%3D 7586153 10.1093/carcin/16.10.2467
    • YJ Surh RC Lee KK Park ST Mayne A Liem JA Miller 1995 Chemoprotective effects of capsaicin and diallyl sulfide against mutagenesis or tumorigenesis by vinyl carbamate and N-nitrosodimethylamine Carcinogenesis 16 2467 2471 1:CAS:528:DyaK2MXovFyrsr4%3D 7586153 10.1093/carcin/16.10.2467
    • (1995) Carcinogenesis , vol.16 , pp. 2467-2471
    • Surh, Y.J.1    Lee, R.C.2    Park, K.K.3    Mayne, S.T.4    Liem, A.5    Miller, J.A.6
  • 42
    • 0037019748 scopus 로고    scopus 로고
    • More than spice: Capsaicin in hot chili peppers makes tumor cells commit suicide
    • 1:CAS:528:DC%2BD38XntVGqtLk%3D 12208886
    • YJ Surh 2002 More than spice: Capsaicin in hot chili peppers makes tumor cells commit suicide Journal of the National Cancer Institute 94 1263 1265 1:CAS:528:DC%2BD38XntVGqtLk%3D 12208886
    • (2002) Journal of the National Cancer Institute , vol.94 , pp. 1263-1265
    • Surh, Y.J.1
  • 43
    • 0035953182 scopus 로고    scopus 로고
    • Capsaicin suppresses phorbol ester-induced activation of NF-κB/Rel and AP-1 transcription factors in mouse epidermis
    • DOI 10.1016/S0304-3835(01)00378-0, PII S0304383501003780
    • SS Han YS Keum HJ Seo KS Chun SS Lee YJ Surh 2001 Capsaicin suppresses phorbol ester-induced activation of NF-kappaB/Rel and AP-1 transcription factors in mouse epidermis Cancer Letters 164 119 126 1:CAS:528:DC%2BD3MXhtFSlt7g%3D 11179825 10.1016/S0304-3835(01)00378-0 (Pubitemid 32155498)
    • (2001) Cancer Letters , vol.164 , Issue.2 , pp. 119-126
    • Han, S.S.1    Keum, Y.-S.2    Seo, H.-J.3    Chun, K.-S.4    Lee, S.S.5    Surh, Y.-J.6
  • 45
    • 0030773543 scopus 로고    scopus 로고
    • Sanguinarine (pseudochelerythrine) is a potent inhibitor of NF-κB activation, IκBα phosphorylation, and degradation
    • DOI 10.1074/jbc.272.48.30129
    • MM Chaturvedi A Kumar BG Darnay GB Chainy S Agarwal BB Aggarwal 1997 Sanguinarine (pseudochelerythrine) is a potent inhibitor of NF-kappaB activation, IkappaBalpha phosphorylation, and degradation The Journal of Biological Chemistry 272 30129 30134 1:CAS:528:DyaK2sXnslGhtLY%3D 9374492 10.1074/jbc.272.48.30129 (Pubitemid 27512211)
    • (1997) Journal of Biological Chemistry , vol.272 , Issue.48 , pp. 30129-30134
    • Chaturvedi, M.M.1    Kumar, A.2    Darnay, B.G.3    Chainy, G.B.N.4    Agarwal, S.5    Aggarwal, B.B.6
  • 46
    • 15444356379 scopus 로고    scopus 로고
    • Emodin (3-methyl-1,6,8-trihydroxyanthraquinone) inhibits TNF-induced NF-kappaB activation, IkappaB degradation, and expression of cell surface adhesion proteins in human vascular endothelial cells
    • 1:CAS:528:DyaK1cXlslGgtr8%3D 9780008 10.1038/sj.onc.1201998
    • A Kumar S Dhawan BB Aggarwal 1998 Emodin (3-methyl-1,6,8- trihydroxyanthraquinone) inhibits TNF-induced NF-kappaB activation, IkappaB degradation, and expression of cell surface adhesion proteins in human vascular endothelial cells Oncogene 17 913 918 1:CAS:528:DyaK1cXlslGgtr8%3D 9780008 10.1038/sj.onc.1201998
    • (1998) Oncogene , vol.17 , pp. 913-918
    • Kumar, A.1    Dhawan, S.2    Aggarwal, B.B.3
  • 47
    • 33745155823 scopus 로고    scopus 로고
    • Alteration of subcellular redox equilibrium and the consequent oxidative modification of nuclear factor κB are critical for anticancer cytotoxicity by emodin, a reactive oxygen species-producing agent
    • DOI 10.1016/j.freeradbiomed.2006.02.016, PII S0891584906001262
    • Y Jing J Yang Y Wang H Li Y Chen Q Hu, et al. 2006 Alteration of subcellular redox equilibrium and the consequent oxidative modification of nuclear factor kappaB are critical for anticancer cytotoxicity by emodin, a reactive oxygen species-producing agent Free Radical Biology & Medicine 40 2183 2197 1:CAS:528:DC%2BD28XlvF2hu70%3D 10.1016/j.freeradbiomed.2006.02.016 (Pubitemid 43903104)
    • (2006) Free Radical Biology and Medicine , vol.40 , Issue.12 , pp. 2183-2197
    • Jing, Y.1    Yang, J.2    Wang, Y.3    Li, H.4    Chen, Y.5    Hu, Q.6    Shi, G.7    Tang, X.8    Yi, J.9
  • 48
    • 0033786929 scopus 로고    scopus 로고
    • Inhibition of 12-O-tetradecanoylphorbol-13-acetate-induced NF-kappaB activation by tea polyphenols, (-)-epigallocatechin gallate and theaflavins
    • 1:CAS:528:DC%2BD3cXnslKmtLg%3D 11023547 10.1093/carcin/21.10.1885
    • M Nomura W Ma N Chen AM Bode Z Dong 2000 Inhibition of 12-O-tetradecanoylphorbol-13-acetate-induced NF-kappaB activation by tea polyphenols, (-)-epigallocatechin gallate and theaflavins Carcinogenesis 21 1885 1890 1:CAS:528:DC%2BD3cXnslKmtLg%3D 11023547 10.1093/carcin/21.10.1885
    • (2000) Carcinogenesis , vol.21 , pp. 1885-1890
    • Nomura, M.1    Ma, W.2    Chen, N.3    Bode, A.M.4    Dong, Z.5
  • 49
    • 0037455718 scopus 로고    scopus 로고
    • Inhibition of ultraviolet B-mediated activation of nuclear factor κB in normal human epidermal keratinocytes by green tea Constituent (-)-epigallocatechin-3-gallate
    • DOI 10.1038/sj.onc.1206206
    • F Afaq VM Adhami N Ahmad H Mukhtar 2003 Inhibition of ultraviolet B-mediated activation of nuclear factor kappaB in normal human epidermal keratinocytes by green tea constituent (-)-epigallocatechin-3-gallate Oncogene 22 1035 1044 1:CAS:528:DC%2BD3sXht1Gktrk%3D 12592390 10.1038/sj.onc.1206206 (Pubitemid 36313147)
    • (2003) Oncogene , vol.22 , Issue.7 , pp. 1035-1044
    • Afaq, F.1    Adhami, V.M.2    Ahmad, N.3    Mukhtar, H.4
  • 50
    • 58349094740 scopus 로고    scopus 로고
    • Epigallocatechin-3-gallate, a histone acetyltransferase inhibitor, inhibits EBV-induced B lymphocyte transformation via suppression of RelA acetylation
    • 1:CAS:528:DC%2BD1MXltFShtg%3D%3D 19147572 10.1158/0008-5472.CAN-08-2442
    • KC Choi MG Jung YH Lee JC Yoon SH Kwon HB Kang, et al. 2009 Epigallocatechin-3-gallate, a histone acetyltransferase inhibitor, inhibits EBV-induced B lymphocyte transformation via suppression of RelA acetylation Cancer Research 69 583 592 1:CAS:528:DC%2BD1MXltFShtg%3D%3D 19147572 10.1158/0008-5472.CAN-08-2442
    • (2009) Cancer Research , vol.69 , pp. 583-592
    • Choi, K.C.1    Jung, M.G.2    Lee, Y.H.3    Yoon, J.C.4    Kwon, S.H.5    Kang, H.B.6
  • 51
    • 73849102273 scopus 로고    scopus 로고
    • Gallic acid suppresses lipopolysaccharide-induced nuclear factor-kappaB signaling by preventing RelA acetylation in A549 lung cancer cells
    • 1:CAS:528:DC%2BD1MXhsFOrt77K 19996305 10.1158/1541-7786.MCR-09-0239
    • KC Choi YH Lee MG Jung SH Kwon MJ Kim WJ Jun, et al. 2009 Gallic acid suppresses lipopolysaccharide-induced nuclear factor-kappaB signaling by preventing RelA acetylation in A549 lung cancer cells Molecular Cancer Research 7 2011 2021 1:CAS:528:DC%2BD1MXhsFOrt77K 19996305 10.1158/1541-7786.MCR-09-0239
    • (2009) Molecular Cancer Research , vol.7 , pp. 2011-2021
    • Choi, K.C.1    Lee, Y.H.2    Jung, M.G.3    Kwon, S.H.4    Kim, M.J.5    Jun, W.J.6
  • 52
    • 46749127067 scopus 로고    scopus 로고
    • Anacardic acid (6-nonadecyl salicylic acid), an inhibitor of histone acetyltransferase, suppresses expression of nuclear factor-kappaB-regulated gene products involved in cell survival, proliferation, invasion, and inflammation through inhibition of the inhibitory subunit of nuclear factor-kappaBalpha kinase, leading to potentiation of apoptosis
    • 1:CAS:528:DC%2BD1cXmtlaitbc%3D 18349320 10.1182/blood-2007-10-117994
    • B Sung MK Pandey KS Ahn T Yi MM Chaturvedi M Liu, et al. 2008 Anacardic acid (6-nonadecyl salicylic acid), an inhibitor of histone acetyltransferase, suppresses expression of nuclear factor-kappaB-regulated gene products involved in cell survival, proliferation, invasion, and inflammation through inhibition of the inhibitory subunit of nuclear factor-kappaBalpha kinase, leading to potentiation of apoptosis Blood 111 4880 4891 1:CAS:528:DC%2BD1cXmtlaitbc%3D 18349320 10.1182/blood-2007-10-117994
    • (2008) Blood , vol.111 , pp. 4880-4891
    • Sung, B.1    Pandey, M.K.2    Ahn, K.S.3    Yi, T.4    Chaturvedi, M.M.5    Liu, M.6
  • 53
    • 0028929328 scopus 로고
    • Mechanisms and genes of cellular suicide
    • 1:CAS:528:DyaK2MXktlClt78%3D 7878463 10.1126/science.7878463
    • H Steller 1995 Mechanisms and genes of cellular suicide Science 267 1445 1449 1:CAS:528:DyaK2MXktlClt78%3D 7878463 10.1126/science.7878463
    • (1995) Science , vol.267 , pp. 1445-1449
    • Steller, H.1
  • 54
    • 0034616946 scopus 로고    scopus 로고
    • Apoptotic pathways: Paper wraps stone blunts scissors
    • 1:CAS:528:DC%2BD3cXkvFCrsbo%3D 10929706 10.1016/S0092-8674(00)00003-9
    • DR Green 2000 Apoptotic pathways: Paper wraps stone blunts scissors Cell 102 1 4 1:CAS:528:DC%2BD3cXkvFCrsbo%3D 10929706 10.1016/S0092-8674(00)00003-9
    • (2000) Cell , vol.102 , pp. 1-4
    • Green, D.R.1
  • 55
    • 0034641980 scopus 로고    scopus 로고
    • Apoptosis in development
    • 1:CAS:528:DC%2BD3cXnsFWrsbg%3D 11048731 10.1038/35037734
    • P Meier A Finch G Evan 2000 Apoptosis in development Nature 407 796 801 1:CAS:528:DC%2BD3cXnsFWrsbg%3D 11048731 10.1038/35037734
    • (2000) Nature , vol.407 , pp. 796-801
    • Meier, P.1    Finch, A.2    Evan, G.3
  • 56
    • 0242721548 scopus 로고    scopus 로고
    • Targeting Bcl-2 and Bcl-XL with nonpeptidic small-molecule antagonists
    • 1:CAS:528:DC%2BD3sXhtVSjtrjO 14613034 10.1053/j.seminoncol.2003.08.015
    • S Wang D Yang ME Lippman 2003 Targeting Bcl-2 and Bcl-XL with nonpeptidic small-molecule antagonists Seminars in Oncology 30 133 142 1:CAS:528: DC%2BD3sXhtVSjtrjO 14613034 10.1053/j.seminoncol.2003.08.015
    • (2003) Seminars in Oncology , vol.30 , pp. 133-142
    • Wang, S.1    Yang, D.2    Lippman, M.E.3
  • 57
    • 0030746636 scopus 로고    scopus 로고
    • A novel anti-apoptosis gene, survivin, expressed in cancer and lymphoma
    • DOI 10.1038/nm0897-917
    • G Ambrosini C Adida DC Altieri 1997 A novel anti-apoptosis gene, survivin, expressed in cancer and lymphoma Nature Medicine 3 917 921 1:CAS:528:DyaK2sXltVylt7w%3D 9256286 10.1038/nm0897-917 (Pubitemid 27353455)
    • (1997) Nature Medicine , vol.3 , Issue.8 , pp. 917-921
    • Ambrosini, G.1    Adida, C.2    Altieri, D.C.3
  • 58
    • 34548549218 scopus 로고    scopus 로고
    • Pro-apoptotic effects of 1′-acetoxychavicol acetate in human breast carcinoma cells
    • DOI 10.1016/j.toxlet.2007.07.008, PII S0378427407007850
    • CT Campbell M Prince GM Landry V Kha HE Kleiner 2007 Pro-apoptotic effects of 1'-acetoxychavicol acetate in human breast carcinoma cells Toxicology Letters 173 151 160 1:CAS:528:DC%2BD2sXhtVeqsrrO 17766064 10.1016/j.toxlet. 2007.07.008 (Pubitemid 47391547)
    • (2007) Toxicology Letters , vol.173 , Issue.3 , pp. 151-160
    • Campbell, C.T.1    Prince, M.2    Landry, G.M.3    Kha, V.4    Kleiner, H.E.5
  • 59
    • 71949097349 scopus 로고    scopus 로고
    • Berberine induced apoptosis via promoting the expression of caspase-8, -9 and -3, apoptosis-inducing factor and endonuclease G in SCC-4 human tongue squamous carcinoma cancer cells
    • 1:CAS:528:DC%2BD1MXhsVOlt7bE 19846952
    • YT Ho CC Lu JS Yang JH Chiang TC Li SW Ip, et al. 2009 Berberine induced apoptosis via promoting the expression of caspase-8, -9 and -3, apoptosis-inducing factor and endonuclease G in SCC-4 human tongue squamous carcinoma cancer cells Anticancer Research 29 4063 4070 1:CAS:528: DC%2BD1MXhsVOlt7bE 19846952
    • (2009) Anticancer Research , vol.29 , pp. 4063-4070
    • Ho, Y.T.1    Lu, C.C.2    Yang, J.S.3    Chiang, J.H.4    Li, T.C.5    Ip, S.W.6
  • 60
    • 58849122415 scopus 로고    scopus 로고
    • P53 cooperates berberine-induced growth inhibition and apoptosis of non-small cell human lung cancer cells in vitro and tumor xenograft growth in vivo
    • 1:CAS:528:DC%2BD1MXmtlKjug%3D%3D 18459128 10.1002/mc.20453
    • SK Katiyar SM Meeran N Katiyar S Akhtar 2009 p53 cooperates berberine-induced growth inhibition and apoptosis of non-small cell human lung cancer cells in vitro and tumor xenograft growth in vivo Molecular Carcinogenesis 48 24 37 1:CAS:528:DC%2BD1MXmtlKjug%3D%3D 18459128 10.1002/mc.20453
    • (2009) Molecular Carcinogenesis , vol.48 , pp. 24-37
    • Katiyar, S.K.1    Meeran, S.M.2    Katiyar, N.3    Akhtar, S.4
  • 61
    • 42449139803 scopus 로고    scopus 로고
    • Flavopiridol suppresses tumor necrosis factor-induced activation of activator protein-1, c-Jun N-terminal kinase, p38 mitogen-activated protein kinase (MAPK), p44/p42 MAPK, and Akt, inhibits expression of antiapoptotic gene products, and enhances apoptosis through cytochrome c release and caspase activation in human myeloid cells
    • DOI 10.1124/mol.107.041350
    • Y Takada G Sethi B Sung BB Aggarwal 2008 Flavopiridol suppresses tumor necrosis factor-induced activation of activator protein-1, c-Jun N-terminal kinase, p38 mitogen-activated protein kinase (MAPK), p44/p42 MAPK, and Akt, inhibits expression of antiapoptotic gene products, and enhances apoptosis through cytochrome c release and caspase activation in human myeloid cells Molecular Pharmacology 73 1549 1557 1:CAS:528:DC%2BD1cXlsVWgu7k%3D 18287248 10.1124/mol.107.041350 (Pubitemid 351574844)
    • (2008) Molecular Pharmacology , vol.73 , Issue.5 , pp. 1549-1557
    • Takada, Y.1    Sethi, G.2    Sung, B.3    Aggarwal, B.B.4
  • 62
    • 70349773507 scopus 로고    scopus 로고
    • Gambogic acid reduced bcl-2 expression via p53 in human breast MCF-7 cancer cells
    • 1:CAS:528:DC%2BD1MXhtFOrt7fL 19582475 10.1007/s00432-009-0624-2
    • H Gu S Rao J Zhao J Wang R Mu J Rong, et al. 2009 Gambogic acid reduced bcl-2 expression via p53 in human breast MCF-7 cancer cells Journal of Cancer Research and Clinical Oncology 135 1777 1782 1:CAS:528:DC%2BD1MXhtFOrt7fL 19582475 10.1007/s00432-009-0624-2
    • (2009) Journal of Cancer Research and Clinical Oncology , vol.135 , pp. 1777-1782
    • Gu, H.1    Rao, S.2    Zhao, J.3    Wang, J.4    Mu, R.5    Rong, J.6
  • 63
    • 59149095869 scopus 로고    scopus 로고
    • Gambogic acid induces apoptosis by regulating the expression of Bax and Bcl-2 and enhancing caspase-3 activity in human malignant melanoma A375 cells
    • 1:CAS:528:DC%2BD1MXjt1Ckur8%3D 19200201 10.1111/j.1365-4632.2009.03946.x
    • X Xu Y Liu L Wang J He H Zhang X Chen, et al. 2009 Gambogic acid induces apoptosis by regulating the expression of Bax and Bcl-2 and enhancing caspase-3 activity in human malignant melanoma A375 cells International Journal of Dermatology 48 186 192 1:CAS:528:DC%2BD1MXjt1Ckur8%3D 19200201 10.1111/j.1365-4632.2009.03946.x
    • (2009) International Journal of Dermatology , vol.48 , pp. 186-192
    • Xu, X.1    Liu, Y.2    Wang, L.3    He, J.4    Zhang, H.5    Chen, X.6
  • 64
    • 26444570963 scopus 로고    scopus 로고
    • Garcinol modulates tyrosine phosphorylation of FAK and subsequently induces apoptosis through down-regulation of Src, ERK, and Akt survival signaling in human colon cancer cells
    • DOI 10.1002/jcb.20540
    • CH Liao S Sang CT Ho JK Lin 2005 Garcinol modulates tyrosine phosphorylation of FAK and subsequently induces apoptosis through down-regulation of Src, ERK, and Akt survival signaling in human colon cancer cells Journal of Cellular Biochemistry 96 155 169 1:CAS:528:DC%2BD2MXpvF2rsbk%3D 16052481 10.1002/jcb.20540 (Pubitemid 41420111)
    • (2005) Journal of Cellular Biochemistry , vol.96 , Issue.1 , pp. 155-169
    • Liao, C.-H.1    Sang, S.2    Ho, C.-T.3    Lin, J.-K.4
  • 65
    • 76749161020 scopus 로고    scopus 로고
    • Indole-3-carbinol induces apoptosis through p53 and activation of caspase-8 pathway in lung cancer A549 cells
    • 1:CAS:528:DC%2BC3cXit1Ortbo%3D 20060030 10.1016/j.fct.2009.12.028
    • HS Choi MC Cho HG Lee DY Yoon 2010 Indole-3-carbinol induces apoptosis through p53 and activation of caspase-8 pathway in lung cancer A549 cells Food and Chemical Toxicology 48 883 890 1:CAS:528:DC%2BC3cXit1Ortbo%3D 20060030 10.1016/j.fct.2009.12.028
    • (2010) Food and Chemical Toxicology , vol.48 , pp. 883-890
    • Choi, H.S.1    Cho, M.C.2    Lee, H.G.3    Yoon, D.Y.4
  • 66
    • 76049106562 scopus 로고    scopus 로고
    • Resveratrol down-regulates survivin and induces apoptosis in human multidrug-resistant SPC-A-1/CDDP cells
    • 1:CAS:528:DC%2BC3cXksl2ltrc%3D 19956893 10.3892/or00000726
    • W Zhao P Bao H Qi H You 2010 Resveratrol down-regulates survivin and induces apoptosis in human multidrug-resistant SPC-A-1/CDDP cells Oncology Reports 23 279 286 1:CAS:528:DC%2BC3cXksl2ltrc%3D 19956893 10.3892/or00000726
    • (2010) Oncology Reports , vol.23 , pp. 279-286
    • Zhao, W.1    Bao, P.2    Qi, H.3    You, H.4
  • 67
    • 75149114612 scopus 로고    scopus 로고
    • Sanguinarine sensitizes human gastric adenocarcinoma AGS cells to TRAIL-mediated apoptosis via down-regulation of AKT and activation of caspase-3
    • 1:CAS:528:DC%2BC3cXptleltw%3D%3D 20032392
    • WY Choi CY Jin MH Han GY Kim ND Kim WH Lee, et al. 2009 Sanguinarine sensitizes human gastric adenocarcinoma AGS cells to TRAIL-mediated apoptosis via down-regulation of AKT and activation of caspase-3 Anticancer Research 29 4457 4465 1:CAS:528:DC%2BC3cXptleltw%3D%3D 20032392
    • (2009) Anticancer Research , vol.29 , pp. 4457-4465
    • Choi, W.Y.1    Jin, C.Y.2    Han, M.H.3    Kim, G.Y.4    Kim, N.D.5    Lee, W.H.6
  • 68
    • 48049115016 scopus 로고    scopus 로고
    • Sanguinarine, a benzophenanthridine alkaloid, induces apoptosis in MDA-MB-231 human breast carcinoma cells through a reactive oxygen species-mediated mitochondrial pathway
    • 1:CAS:528:DC%2BD1cXhtVejsL%2FE 18667818 10.1159/000149719
    • WY Choi GY Kim WH Lee YH Choi 2008 Sanguinarine, a benzophenanthridine alkaloid, induces apoptosis in MDA-MB-231 human breast carcinoma cells through a reactive oxygen species-mediated mitochondrial pathway Chemotherapy 54 279 287 1:CAS:528:DC%2BD1cXhtVejsL%2FE 18667818 10.1159/000149719
    • (2008) Chemotherapy , vol.54 , pp. 279-287
    • Choi, W.Y.1    Kim, G.Y.2    Lee, W.H.3    Choi, Y.H.4
  • 69
    • 46449110814 scopus 로고    scopus 로고
    • Sanguinarine-induced apoptosis in human leukemia U937 cells via Bcl-2 downregulation and caspase-3 activation
    • DOI 10.1159/000140359
    • MH Han YH Yoo YH Choi 2008 Sanguinarine-induced apoptosis in human leukemia U937 cells via Bcl-2 downregulation and caspase-3 activation Chemotherapy 54 157 165 1:CAS:528:DC%2BD1cXnvFeitbs%3D 18560221 10.1159/000140359 (Pubitemid 351929265)
    • (2008) Chemotherapy , vol.54 , Issue.3 , pp. 157-165
    • Han, M.H.1    Yoo, Y.H.2    Choi, Y.H.3
  • 70
    • 36448981749 scopus 로고    scopus 로고
    • Curcumin enhances the apoptosis-inducing potential of TRAIL in prostate cancer cells: Molecular mechanisms of apoptosis, migration and angiogenesis
    • DOI 10.1186/1750-2187-2-10
    • S Shankar Q Chen K Sarva I Siddiqui RK Srivastava 2007 Curcumin enhances the apoptosis-inducing potential of TRAIL in prostate cancer cells: Molecular mechanisms of apoptosis, migration and angiogenesis Journal of Molecular Signaling 2 10 17916240 10.1186/1750-2187-2-10 1:CAS:528:DC%2BD2sXhtlajtb%2FF (Pubitemid 350162838)
    • (2007) Journal of Molecular Signaling , vol.2 , pp. 10
    • Shankar, S.1    Chen, Q.2    Sarva, K.3    Siddiqui, I.4    Srivastava, R.K.5
  • 71
    • 34247850953 scopus 로고    scopus 로고
    • Involvement of Bcl-2 family members, phosphatidylinositol 3'-kinase/AKT and mitochondrial p53 in curcumin (diferuloylmethane)-induced apoptosis in prostate cancer
    • 1:CAS:528:DC%2BD2sXkt1WhtLo%3D 17332930
    • S Shankar RK Srivastava 2007 Involvement of Bcl-2 family members, phosphatidylinositol 3'-kinase/AKT and mitochondrial p53 in curcumin (diferuloylmethane)-induced apoptosis in prostate cancer International Journal of Oncology 30 905 918 1:CAS:528:DC%2BD2sXkt1WhtLo%3D 17332930
    • (2007) International Journal of Oncology , vol.30 , pp. 905-918
    • Shankar, S.1    Srivastava, R.K.2
  • 72
    • 67650080174 scopus 로고    scopus 로고
    • The XIAP inhibitor embelin enhances TRAIL-mediated apoptosis in malignant glioma cells by down-regulation of the short isoform of FLIP
    • 1:CAS:528:DC%2BD1MXoslSju7c%3D 19409438 10.1016/j.neuint.2009.04.011
    • MD Siegelin T Gaiser Y Siegelin 2009 The XIAP inhibitor embelin enhances TRAIL-mediated apoptosis in malignant glioma cells by down-regulation of the short isoform of FLIP Neurochemistry International 55 423 430 1:CAS:528:DC%2BD1MXoslSju7c%3D 19409438 10.1016/j.neuint.2009.04.011
    • (2009) Neurochemistry International , vol.55 , pp. 423-430
    • Siegelin, M.D.1    Gaiser, T.2    Siegelin, Y.3
  • 73
    • 75349102170 scopus 로고    scopus 로고
    • Chalcones enhance TRAIL-induced apoptosis in prostate cancer cells
    • 20161998 10.3390/ijms11010001 1:CAS:528:DC%2BC3cXis1Wjtw%3D%3D
    • E Szliszka ZP Czuba B Mazur L Sedek A Paradysz W Krol 2009 Chalcones enhance TRAIL-induced apoptosis in prostate cancer cells International Journal of Molecular Sciences 11 1 13 20161998 10.3390/ijms11010001 1:CAS:528: DC%2BC3cXis1Wjtw%3D%3D
    • (2009) International Journal of Molecular Sciences , vol.11 , pp. 1-13
    • Szliszka, E.1    Czuba, Z.P.2    Mazur, B.3    Sedek, L.4    Paradysz, A.5    Krol, W.6
  • 74
    • 26244437262 scopus 로고    scopus 로고
    • Xanthohumol induces apoptosis in cultured 40-16 human colon cancer cells by activation of the death receptor- and mitochondrial pathway
    • DOI 10.1002/mnfr.200500065
    • L Pan H Becker C Gerhauser 2005 Xanthohumol induces apoptosis in cultured 40-16 human colon cancer cells by activation of the death receptor- and mitochondrial pathway Molecular Nutrition & Food Research 49 837 843 1:CAS:528:DC%2BD2MXhtFyiu7jF 10.1002/mnfr.200500065 (Pubitemid 41411567)
    • (2005) Molecular Nutrition and Food Research , vol.49 , Issue.9 , pp. 837-843
    • Pan, L.1    Becker, H.2    Gerhauser, C.3
  • 75
    • 34047261665 scopus 로고    scopus 로고
    • Betulinic acid inhibits prostate cancer growth through inhibition of specificity protein transcription factors
    • DOI 10.1158/0008-5472.CAN-06-3735
    • S Chintharlapalli S Papineni SK Ramaiah S Safe 2007 Betulinic acid inhibits prostate cancer growth through inhibition of specificity protein transcription factors Cancer Research 67 2816 2823 1:CAS:528: DC%2BD2sXivV2nsbw%3D 17363604 10.1158/0008-5472.CAN-06-3735 (Pubitemid 46548971)
    • (2007) Cancer Research , vol.67 , Issue.6 , pp. 2816-2823
    • Chintharlapalli, S.1    Papineni, S.2    Ramaiah, S.K.3    Safe, S.4
  • 76
    • 33745228422 scopus 로고    scopus 로고
    • Cardiac glycosides initiate Apo2L/TRAIL-induced apoptosis in non-small cell lung cancer cells by up-regulation of death receptors 4 and 5
    • DOI 10.1158/0008-5472.CAN-05-3544
    • S Frese M Frese-Schaper AC Andres D Miescher B Zumkehr RA Schmid 2006 Cardiac glycosides initiate Apo2L/TRAIL-induced apoptosis in non-small cell lung cancer cells by up-regulation of death receptors 4 and 5 Cancer Research 66 5867 5874 1:CAS:528:DC%2BD28XltFyjur4%3D 16740726 10.1158/0008-5472.CAN-05-3544 (Pubitemid 43927141)
    • (2006) Cancer Research , vol.66 , Issue.11 , pp. 5867-5874
    • Frese, S.1    Frese-Schaper, M.2    Andres, A.-C.3    Miescher, D.4    Zumkehr, B.5    Schmid, R.A.6
  • 77
    • 77950796660 scopus 로고    scopus 로고
    • Garcinol potentiates TRAIL-induced apoptosis through modulation of death receptors and antiapoptotic proteins
    • 1:CAS:528:DC%2BC3cXktlCqt78%3D 20371723 10.1158/1535-7163.MCT-09-1113
    • S Prasad J Ravindran B Sung MK Pandey BB Aggarwal 2010 Garcinol potentiates TRAIL-induced apoptosis through modulation of death receptors and antiapoptotic proteins Molecular Cancer Therapeutics 9 856 868 1:CAS:528:DC%2BC3cXktlCqt78%3D 20371723 10.1158/1535-7163.MCT-09-1113
    • (2010) Molecular Cancer Therapeutics , vol.9 , pp. 856-868
    • Prasad, S.1    Ravindran, J.2    Sung, B.3    Pandey, M.K.4    Aggarwal, B.B.5
  • 78
    • 77950890084 scopus 로고    scopus 로고
    • Capsaicin sensitizes malignant glioma cells to TRAIL-mediated apoptosis via DR5 upregulation and survivin downregulation
    • 1:CAS:528:DC%2BC3cXivFGms70%3D 19939880 10.1093/carcin/bgp298
    • JY Kim EH Kim SU Kim TK Kwon KS Choi 2010 Capsaicin sensitizes malignant glioma cells to TRAIL-mediated apoptosis via DR5 upregulation and survivin downregulation Carcinogenesis 31 367 375 1:CAS:528:DC%2BC3cXivFGms70%3D 19939880 10.1093/carcin/bgp298
    • (2010) Carcinogenesis , vol.31 , pp. 367-375
    • Kim, J.Y.1    Kim, E.H.2    Kim, S.U.3    Kwon, T.K.4    Choi, K.S.5
  • 79
    • 77951215549 scopus 로고    scopus 로고
    • Celastrol, a triterpene, enhances TRAIL-induced apoptosis through the down-regulation of cell survival proteins and up-regulation of death receptors
    • 1:CAS:528:DC%2BC3cXktFGlt7o%3D 20154087 10.1074/jbc.M109.090209
    • B Sung B Park VR Yadav BB Aggarwal 2010 Celastrol, a triterpene, enhances TRAIL-induced apoptosis through the down-regulation of cell survival proteins and up-regulation of death receptors The Journal of Biological Chemistry 285 11498 11507 1:CAS:528:DC%2BC3cXktFGlt7o%3D 20154087 10.1074/jbc.M109.090209
    • (2010) The Journal of Biological Chemistry , vol.285 , pp. 11498-11507
    • Sung, B.1    Park, B.2    Yadav, V.R.3    Aggarwal, B.B.4
  • 80
    • 69249083578 scopus 로고    scopus 로고
    • Zerumbone enhances TRAIL-induced apoptosis through the induction of death receptors in human colon cancer cells: Evidence for an essential role of reactive oxygen species
    • 1:CAS:528:DC%2BD1MXpvFejt7k%3D 19654295 10.1158/0008-5472.CAN-09-1161
    • S Yodkeeree B Sung P Limtrakul BB Aggarwal 2009 Zerumbone enhances TRAIL-induced apoptosis through the induction of death receptors in human colon cancer cells: Evidence for an essential role of reactive oxygen species Cancer Research 69 6581 6589 1:CAS:528:DC%2BD1MXpvFejt7k%3D 19654295 10.1158/0008-5472.CAN-09-1161
    • (2009) Cancer Research , vol.69 , pp. 6581-6589
    • Yodkeeree, S.1    Sung, B.2    Limtrakul, P.3    Aggarwal, B.B.4
  • 81
    • 34247218059 scopus 로고    scopus 로고
    • Zerumbone induced apoptosis in liver cancer cells via modulation of Bax/ Bcl-2 ratio
    • DOI 10.1186/1475-2867-7-4
    • SA Sakinah ST Handayani LP Hawariah 2007 Zerumbone induced apoptosis in liver cancer cells via modulation of Bax/Bcl-2 ratio Cancer Cell International 7 4 17407577 10.1186/1475-2867-7-4 1:CAS:528:DC%2BD2sXmsVOrsLg%3D (Pubitemid 46605896)
    • (2007) Cancer Cell International , vol.7 , pp. 4
    • Sakinah, S.A.S.1    Tri Handayani, S.2    Hawariah, L.P.A.3
  • 82
    • 77952126276 scopus 로고    scopus 로고
    • Inhibition of the insulin-like growth factor i receptor by epigallocatechin gallate blocks proliferation and induces the death of Ewing tumor cells
    • 1:CAS:528:DC%2BC3cXlslektLk%3D 20423994 10.1158/1535-7163.MCT-09-0604
    • HG Kang JM Jenabi XF Liu CP Reynolds TJ Triche PH Sorensen 2010 Inhibition of the insulin-like growth factor I receptor by epigallocatechin gallate blocks proliferation and induces the death of Ewing tumor cells Molecular Cancer Therapeutics 9 1396 1407 1:CAS:528:DC%2BC3cXlslektLk%3D 20423994 10.1158/1535-7163.MCT-09-0604
    • (2010) Molecular Cancer Therapeutics , vol.9 , pp. 1396-1407
    • Kang, H.G.1    Jenabi, J.M.2    Liu, X.F.3    Reynolds, C.P.4    Triche, T.J.5    Sorensen, P.H.6
  • 83
    • 71549153495 scopus 로고    scopus 로고
    • Genistein induces G2/M cell cycle arrest and apoptosis of human ovarian cancer cells via activation of DNA damage checkpoint pathways
    • 1:CAS:528:DC%2BD1MXhsVGltbbM 19732843 10.1016/j.cellbi.2009.08.011
    • G Ouyang L Yao K Ruan G Song Y Mao S Bao 2009 Genistein induces G2/M cell cycle arrest and apoptosis of human ovarian cancer cells via activation of DNA damage checkpoint pathways Cell Biology International 33 1237 1244 1:CAS:528:DC%2BD1MXhsVGltbbM 19732843 10.1016/j.cellbi.2009.08.011
    • (2009) Cell Biology International , vol.33 , pp. 1237-1244
    • Ouyang, G.1    Yao, L.2    Ruan, K.3    Song, G.4    Mao, Y.5    Bao, S.6
  • 84
    • 62449192292 scopus 로고    scopus 로고
    • Silymarin inhibited proliferation and induced apoptosis in hepatic cancer cells
    • 1:CAS:528:DC%2BD1MXkvVWrtrY%3D 19317806 10.1111/j.1365-2184.2008.00581.x
    • G Ramakrishnan L Lo Muzio CM Elinos-Baez S Jagan TA Augustine S Kamaraj, et al. 2009 Silymarin inhibited proliferation and induced apoptosis in hepatic cancer cells Cell Proliferation 42 229 240 1:CAS:528:DC%2BD1MXkvVWrtrY%3D 19317806 10.1111/j.1365-2184.2008.00581.x
    • (2009) Cell Proliferation , vol.42 , pp. 229-240
    • Ramakrishnan, G.1    Lo Muzio, L.2    Elinos-Baez, C.M.3    Jagan, S.4    Augustine, T.A.5    Kamaraj, S.6
  • 86
    • 34249792353 scopus 로고    scopus 로고
    • Capsaicin is a novel blocker of constitutive and interleukin-6 - Inducible STAT3 activation
    • DOI 10.1158/1078-0432.CCR-06-2575
    • M Bhutani AK Pathak AS Nair AB Kunnumakkara S Guha G Sethi, et al. 2007 Capsaicin is a novel blocker of constitutive and interleukin-6-inducible STAT3 activation Clinical Cancer Research 13 3024 3032 1:CAS:528:DC%2BD2sXlt1Krt7k%3D 17505005 10.1158/1078-0432.CCR-06-2575 (Pubitemid 46849579)
    • (2007) Clinical Cancer Research , vol.13 , Issue.10 , pp. 3024-3032
    • Bhutani, M.1    Pathak, A.K.2    Nair, A.S.3    Kunnumakkara, A.B.4    Guha, S.5    Sethi, G.6    Aggarwal, B.B.7
  • 87
    • 77649185645 scopus 로고    scopus 로고
    • Deguelin suppresses cell proliferation via the inhibition of survivin expression and STAT3 phosphorylation in HTLV-1-transformed T cells
    • 1:CAS:528:DC%2BC3cXitVKlu7w%3D 19781773 10.1016/j.leukres.2009.09.003
    • S Ito T Oyake K Murai Y Ishida 2010 Deguelin suppresses cell proliferation via the inhibition of survivin expression and STAT3 phosphorylation in HTLV-1-transformed T cells Leukemia Research 34 352 357 1:CAS:528:DC%2BC3cXitVKlu7w%3D 19781773 10.1016/j.leukres.2009.09.003
    • (2010) Leukemia Research , vol.34 , pp. 352-357
    • Ito, S.1    Oyake, T.2    Murai, K.3    Ishida, Y.4
  • 88
    • 33749524818 scopus 로고    scopus 로고
    • Deguelin, an Akt inhibitor, suppresses IkappaBalpha kinase activation leading to suppression of NF-kappaB-regulated gene expression, potentiation of apoptosis, and inhibition of cellular invasion
    • 1:CAS:528:DC%2BD28XhtVans77L
    • AS Nair S Shishodia KS Ahn AB Kunnumakkara G Sethi BB Aggarwal 2006 Deguelin, an Akt inhibitor, suppresses IkappaBalpha kinase activation leading to suppression of NF-kappaB-regulated gene expression, potentiation of apoptosis, and inhibition of cellular invasion Journal of Immunology 177 5612 5622 1:CAS:528:DC%2BD28XhtVans77L
    • (2006) Journal of Immunology , vol.177 , pp. 5612-5622
    • Nair, A.S.1    Shishodia, S.2    Ahn, K.S.3    Kunnumakkara, A.B.4    Sethi, G.5    Aggarwal, B.B.6
  • 89
    • 12144286272 scopus 로고    scopus 로고
    • Induction of Apoptosis in Human Myeloid Leukemic Cells by 1′-Acetoxychavicol Acetate through a Mitochondrial- and Fas-Mediated Dual Mechanism
    • DOI 10.1158/1078-0432.CCR-1142-03
    • K Ito T Nakazato A Murakami K Yamato Y Miyakawa T Yamada, et al. 2004 Induction of apoptosis in human myeloid leukemic cells by 1'-acetoxychavicol acetate through a mitochondrial- and Fas-mediated dual mechanism Clinical Cancer Research 10 2120 2130 1:CAS:528:DC%2BD2cXisVGks74%3D 15041733 10.1158/1078-0432.CCR-1142-03 (Pubitemid 38375574)
    • (2004) Clinical Cancer Research , vol.10 , Issue.6 , pp. 2120-2130
    • Ito, K.1    Nakazato, T.2    Murakami, A.3    Yamato, K.4    Miyakawa, Y.5    Yamada, T.6    Hozumi, N.7    Ohigashi, H.8    Ikeda, Y.9    Kizaki, M.10
  • 90
    • 77951719892 scopus 로고    scopus 로고
    • Apoptosis-inducing effect of garcinol is mediated by NF-kappaB signaling in breast cancer cells
    • 1:CAS:528:DC%2BC3cXktFyqsr8%3D 20108249
    • A Ahmad Z Wang R Ali MY Maitah D Kong S Banerjee, et al. 2010 Apoptosis-inducing effect of garcinol is mediated by NF-kappaB signaling in breast cancer cells Journal of Cellular Biochemistry 109 1134 1141 1:CAS:528:DC%2BC3cXktFyqsr8%3D 20108249
    • (2010) Journal of Cellular Biochemistry , vol.109 , pp. 1134-1141
    • Ahmad, A.1    Wang, Z.2    Ali, R.3    Maitah, M.Y.4    Kong, D.5    Banerjee, S.6
  • 91
    • 57349119169 scopus 로고    scopus 로고
    • Plumbagin-induced apoptosis of human breast cancer cells is mediated by inactivation of NF-kappaB and Bcl-2
    • 1:CAS:528:DC%2BD1cXhsFaksL7J 18980240 10.1002/jcb.21966
    • A Ahmad S Banerjee Z Wang D Kong FH Sarkar 2008 Plumbagin-induced apoptosis of human breast cancer cells is mediated by inactivation of NF-kappaB and Bcl-2 Journal of Cellular Biochemistry 105 1461 1471 1:CAS:528: DC%2BD1cXhsFaksL7J 18980240 10.1002/jcb.21966
    • (2008) Journal of Cellular Biochemistry , vol.105 , pp. 1461-1471
    • Ahmad, A.1    Banerjee, S.2    Wang, Z.3    Kong, D.4    Sarkar, F.H.5
  • 92
    • 42549115710 scopus 로고    scopus 로고
    • Anticancer mechanism of plumbagin, a natural compound, on non-small cell lung cancer cells
    • 1:CAS:528:DC%2BD1cXmt1eiu7k%3D 18507021
    • R Gomathinayagam S Sowmyalakshmi F Mardhatillah R Kumar MA Akbarsha C Damodaran 2008 Anticancer mechanism of plumbagin, a natural compound, on non-small cell lung cancer cells Anticancer Research 28 785 792 1:CAS:528:DC%2BD1cXmt1eiu7k%3D 18507021
    • (2008) Anticancer Research , vol.28 , pp. 785-792
    • Gomathinayagam, R.1    Sowmyalakshmi, S.2    Mardhatillah, F.3    Kumar, R.4    Akbarsha, M.A.5    Damodaran, C.6
  • 93
    • 70349881605 scopus 로고    scopus 로고
    • Fisetin, a natural flavonoid, targets chemoresistant human pancreatic cancer AsPC-1 cells through DR3-mediated inhibition of NF-kappaB
    • 1:CAS:528:DC%2BD1MXhtFOkt7%2FI 10.1002/ijc.24628
    • I Murtaza VM Adhami BB Hafeez M Saleem H Mukhtar 2009 Fisetin, a natural flavonoid, targets chemoresistant human pancreatic cancer AsPC-1 cells through DR3-mediated inhibition of NF-kappaB International Journal of Cancer 125 2465 2473 1:CAS:528:DC%2BD1MXhtFOkt7%2FI 10.1002/ijc.24628
    • (2009) International Journal of Cancer , vol.125 , pp. 2465-2473
    • Murtaza, I.1    Adhami, V.M.2    Hafeez, B.B.3    Saleem, M.4    Mukhtar, H.5
  • 94
    • 58149234401 scopus 로고    scopus 로고
    • Sulforaphane enhances the therapeutic potential of TRAIL in prostate cancer orthotopic model through regulation of apoptosis, metastasis, and angiogenesis
    • 1:CAS:528:DC%2BD1cXhtlens7nN 18980980 10.1158/1078-0432.CCR-08-0903
    • S Shankar S Ganapathy RK Srivastava 2008 Sulforaphane enhances the therapeutic potential of TRAIL in prostate cancer orthotopic model through regulation of apoptosis, metastasis, and angiogenesis Clinical Cancer Research 14 6855 6866 1:CAS:528:DC%2BD1cXhtlens7nN 18980980 10.1158/1078-0432.CCR-08-0903
    • (2008) Clinical Cancer Research , vol.14 , pp. 6855-6866
    • Shankar, S.1    Ganapathy, S.2    Srivastava, R.K.3
  • 95
    • 18944399076 scopus 로고    scopus 로고
    • Identification of a novel blocker of i kappa B alpha kinase that enhances cellular apoptosis and inhibits cellular invasion through suppression of NF-kappa B-regulated gene products
    • 1:CAS:528:DC%2BD2MXkt1Ols7o%3D
    • H Ichikawa Y Takada A Murakami BB Aggarwal 2005 Identification of a novel blocker of I kappa B alpha kinase that enhances cellular apoptosis and inhibits cellular invasion through suppression of NF-kappa B-regulated gene products Journal of Immunology 174 7383 7392 1:CAS:528:DC%2BD2MXkt1Ols7o%3D
    • (2005) Journal of Immunology , vol.174 , pp. 7383-7392
    • Ichikawa, H.1    Takada, Y.2    Murakami, A.3    Aggarwal, B.B.4
  • 96
    • 20444504721 scopus 로고    scopus 로고
    • Evodiamine abolishes constitutive and inducible NF-κB activation by inhibiting IκBα kinase activation, thereby suppressing NF-κB-regulated antiapoptotic and metastatic gene expression, up-regulating apoptosis, and inhibiting invasion
    • DOI 10.1074/jbc.M500077200
    • Y Takada Y Kobayashi BB Aggarwal 2005 Evodiamine abolishes constitutive and inducible NF-kappaB activation by inhibiting IkappaBalpha kinase activation, thereby suppressing NF-kappaB-regulated antiapoptotic and metastatic gene expression, up-regulating apoptosis, and inhibiting invasion The Journal of Biological Chemistry 280 17203 17212 1:CAS:528:DC%2BD2MXjsFOgtb0%3D 15710601 10.1074/jbc.M500077200 (Pubitemid 41389187)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.17 , pp. 17203-17212
    • Takada, Y.1    Kobayashi, Y.2    Aggarwal, B.B.3
  • 97
    • 77951049854 scopus 로고    scopus 로고
    • Noscapine, a benzylisoquinoline alkaloid, sensitizes leukemic cells to chemotherapeutic agents and cytokines by modulating the NF-kappaB signaling pathway
    • 1:CAS:528:DC%2BC3cXkslShtbc%3D 20354190 10.1158/0008-5472.CAN-09-4230
    • B Sung KS Ahn BB Aggarwal 2010 Noscapine, a benzylisoquinoline alkaloid, sensitizes leukemic cells to chemotherapeutic agents and cytokines by modulating the NF-kappaB signaling pathway Cancer Research 70 3259 3268 1:CAS:528:DC%2BC3cXkslShtbc%3D 20354190 10.1158/0008-5472.CAN-09-4230
    • (2010) Cancer Research , vol.70 , pp. 3259-3268
    • Sung, B.1    Ahn, K.S.2    Aggarwal, B.B.3
  • 98
    • 33747698455 scopus 로고    scopus 로고
    • Indirubin enhances tumor necrosis factor-induced apoptosis through modulation of nuclear factor-κB signaling pathway
    • DOI 10.1074/jbc.M602627200
    • G Sethi KS Ahn SK Sandur X Lin MM Chaturvedi BB Aggarwal 2006 Indirubin enhances tumor necrosis factor-induced apoptosis through modulation of nuclear factor-kappa B signaling pathway The Journal of Biological Chemistry 281 23425 23435 1:CAS:528:DC%2BD28XotVCmt70%3D 16785236 10.1074/jbc.M602627200 (Pubitemid 44274117)
    • (2006) Journal of Biological Chemistry , vol.281 , Issue.33 , pp. 23425-23435
    • Sethi, G.1    Kwang, S.A.2    Sandur, S.K.3    Lin, X.4    Chaturvedi, M.M.5    Aggarwal, B.B.6
  • 99
    • 33750291697 scopus 로고    scopus 로고
    • Isodeoxyelephantopin, a novel sesquiterpene lactone, potentiates apoptosis, inhibits invasion, and abolishes osteoclastogenesis through suppression of nuclear factor-κB (NF-κB) activation and NF-κB-regulated gene expression
    • DOI 10.1158/1078-0432.CCR-06-0916
    • H Ichikawa MS Nair Y Takada DB Sheeja MA Kumar OV Oommen, et al. 2006 Isodeoxyelephantopin, a novel sesquiterpene lactone, potentiates apoptosis, inhibits invasion, and abolishes osteoclastogenesis through suppression of nuclear factor-kappaB (nf-kappaB) activation and nf-kappaB-regulated gene expression Clinical Cancer Research 12 5910 5918 1:CAS:528:DC%2BD28XhtVartbnJ 17021000 10.1158/1078-0432.CCR-06-0916 (Pubitemid 44629625)
    • (2006) Clinical Cancer Research , vol.12 , Issue.19 , pp. 5910-5918
    • Ichikawa, H.1    Nair, M.S.2    Takada, Y.3    Sheeja, D.B.A.4    Kumar, M.A.S.5    Oommen, O.V.6    Aggarwal, B.B.7
  • 100
    • 55749110743 scopus 로고    scopus 로고
    • Coronarin D, a labdane diterpene, inhibits both constitutive and inducible nuclear factor-kappa B pathway activation, leading to potentiation of apoptosis, inhibition of invasion, and suppression of osteoclastogenesis
    • 1:CAS:528:DC%2BD1cXht1ensb%2FK 18852134 10.1158/1535-7163.MCT-08-0432
    • AB Kunnumakkara H Ichikawa P Anand CJ Mohankumar PS Hema MS Nair, et al. 2008 Coronarin D, a labdane diterpene, inhibits both constitutive and inducible nuclear factor-kappa B pathway activation, leading to potentiation of apoptosis, inhibition of invasion, and suppression of osteoclastogenesis Molecular Cancer Therapeutics 7 3306 3317 1:CAS:528:DC%2BD1cXht1ensb%2FK 18852134 10.1158/1535-7163.MCT-08-0432
    • (2008) Molecular Cancer Therapeutics , vol.7 , pp. 3306-3317
    • Kunnumakkara, A.B.1    Ichikawa, H.2    Anand, P.3    Mohankumar, C.J.4    Hema, P.S.5    Nair, M.S.6
  • 101
    • 50349098189 scopus 로고    scopus 로고
    • Targeting nuclear factor-kappa B activation pathway by thymoquinone: Role in suppression of antiapoptotic gene products and enhancement of apoptosis
    • 1:CAS:528:DC%2BD1cXnsVKhur0%3D 18567808 10.1158/1541-7786.MCR-07-2088
    • G Sethi KS Ahn BB Aggarwal 2008 Targeting nuclear factor-kappa B activation pathway by thymoquinone: role in suppression of antiapoptotic gene products and enhancement of apoptosis Molecular Cancer Research 6 1059 1070 1:CAS:528:DC%2BD1cXnsVKhur0%3D 18567808 10.1158/1541-7786.MCR-07-2088
    • (2008) Molecular Cancer Research , vol.6 , pp. 1059-1070
    • Sethi, G.1    Ahn, K.S.2    Aggarwal, B.B.3
  • 102
    • 33846998312 scopus 로고    scopus 로고
    • γ-tocotrienol inhibits nuclear factor-κB signaling pathway through inhibition of receptor-interacting protein and TAK1 leading to suppression of antiapoptotic gene products and potentiation of apoptosis
    • DOI 10.1074/jbc.M610028200
    • KS Ahn G Sethi K Krishnan BB Aggarwal 2007 Gamma-tocotrienol inhibits nuclear factor-kappaB signaling pathway through inhibition of receptor-interacting protein and TAK1 leading to suppression of antiapoptotic gene products and potentiation of apoptosis The Journal of Biological Chemistry 282 809 820 1:CAS:528:DC%2BD2sXkslCr 17114179 10.1074/jbc.M610028200 (Pubitemid 47076658)
    • (2007) Journal of Biological Chemistry , vol.282 , Issue.1 , pp. 809-820
    • Kwang, S.A.1    Sethi, G.2    Krishnan, K.3    Aggarwal, B.B.4
  • 103
    • 77951035820 scopus 로고    scopus 로고
    • Escin, a pentacyclic triterpene, chemosensitizes human tumor cells through inhibition of nuclear factor-kappaB signaling pathway
    • 1:CAS:528:DC%2BC3cXlsVWqt70%3D 20103608 10.1124/mol.109.062760
    • KB Harikumar B Sung MK Pandey S Guha S Krishnan BB Aggarwal 2010 Escin, a pentacyclic triterpene, chemosensitizes human tumor cells through inhibition of nuclear factor-kappaB signaling pathway Molecular Pharmacology 77 818 827 1:CAS:528:DC%2BC3cXlsVWqt70%3D 20103608 10.1124/mol.109.062760
    • (2010) Molecular Pharmacology , vol.77 , pp. 818-827
    • Harikumar, K.B.1    Sung, B.2    Pandey, M.K.3    Guha, S.4    Krishnan, S.5    Aggarwal, B.B.6
  • 104
    • 33746048055 scopus 로고    scopus 로고
    • Withanolides potentiate apoptosis, inhibit invasion, and abolish osteoclastogenesis through suppression of nuclear factor-ΚB (NF-ΚB) activation and NF-ΚB-regulated gene expression
    • DOI 10.1158/1535-7163.MCT-06-0096
    • H Ichikawa Y Takada S Shishodia B Jayaprakasam MG Nair BB Aggarwal 2006 Withanolides potentiate apoptosis, inhibit invasion, and abolish osteoclastogenesis through suppression of nuclear factor-kappaB (NF-kappaB) activation and NF-kappaB-regulated gene expression Molecular Cancer Therapeutics 5 1434 1445 1:CAS:528:DC%2BD28XmsVamsrg%3D 16818501 10.1158/1535-7163.MCT-06- 0096 (Pubitemid 44070479)
    • (2006) Molecular Cancer Therapeutics , vol.5 , Issue.6 , pp. 1434-1445
    • Ichikawa, H.1    Takada, Y.2    Shishodia, S.3    Jayaprakasam, B.4    Nair, M.G.5    Aggarwal, B.B.6
  • 105
    • 0023227831 scopus 로고
    • 1
    • DOI 10.1038/328445a0
    • R Heikkila G Schwab E Wickstrom SL Loke DH Pluznik R Watt, et al. 1987 A c-myc antisense oligodeoxynucleotide inhibits entry into S phase but not progress from G0 to G1 Nature 328 445 449 1:CAS:528:DyaL2sXlsFaltr0%3D 3302722 10.1038/328445a0 (Pubitemid 17097780)
    • (1987) Nature , vol.328 , Issue.6129 , pp. 445-449
    • Heikkila, R.1    Schwab, G.2    Wickstrom, E.3
  • 106
    • 0029917720 scopus 로고    scopus 로고
    • Myc oncogenes: The enigmatic family
    • 1:CAS:528:DyaK28XhvFyjsLk%3D 8615760
    • KM Ryan GD Birnie 1996 Myc oncogenes: The enigmatic family The Biochemical Journal 314 Pt 3 713 721 1:CAS:528:DyaK28XhvFyjsLk%3D 8615760
    • (1996) The Biochemical Journal , vol.314 , Issue.PART 3 , pp. 713-721
    • Ryan, K.M.1    Birnie, G.D.2
  • 107
    • 0027502539 scopus 로고
    • The role of c-myc in cell growth
    • 1:CAS:528:DyaK3sXitV2kt7o%3D 10.1016/S0959-437X(05)80339-9
    • GI Evan TD Littlewood 1993 The role of c-myc in cell growth Current Opinion in Genetics & Development 3 44 49 1:CAS:528:DyaK3sXitV2kt7o%3D 10.1016/S0959-437X(05)80339-9
    • (1993) Current Opinion in Genetics & Development , vol.3 , pp. 44-49
    • Evan, G.I.1    Littlewood, T.D.2
  • 109
    • 0028220204 scopus 로고
    • P53-dependent inhibition of cyclin-dependent kinase activities in human fibroblasts during radiation-induced G1 arrest
    • DOI 10.1016/0092-8674(94)90379-4
    • V Dulic WK Kaufmann SJ Wilson TD Tlsty E Lees JW Harper, et al. 1994 p53-dependent inhibition of cyclin-dependent kinase activities in human fibroblasts during radiation-induced G1 arrest Cell 76 1013 1023 1:CAS:528:DyaK2cXitl2hs7k%3D 8137420 10.1016/0092-8674(94)90379-4 (Pubitemid 24106382)
    • (1994) Cell , vol.76 , Issue.6 , pp. 1013-1023
    • Dullc, V.1    Kaufmann, W.K.2    Wilson, S.J.3    Tlsty, T.D.4    Lees, E.5    Wade Harper, J.6    Elledge, S.J.7    Reed, S.I.8
  • 111
    • 0029033861 scopus 로고
    • The retinoblastoma protein and cell cycle control
    • 1:CAS:528:DyaK2MXlsFSrs7k%3D 7736585 10.1016/0092-8674(95)90385-2
    • RA Weinberg 1995 The retinoblastoma protein and cell cycle control Cell 81 323 330 1:CAS:528:DyaK2MXlsFSrs7k%3D 7736585 10.1016/0092-8674(95)90385-2
    • (1995) Cell , vol.81 , pp. 323-330
    • Weinberg, R.A.1
  • 112
    • 0031945458 scopus 로고    scopus 로고
    • Cell cycle regulation and apoptosis
    • DOI 10.1146/annurev.physiol.60.1.601
    • KL King JA Cidlowski 1998 Cell cycle regulation and apoptosis Annual Review of Physiology 60 601 617 1:CAS:528:DyaK1cXitVOhsbo%3D 9558478 10.1146/annurev.physiol.60.1.601 (Pubitemid 28157888)
    • (1998) Annual Review of Physiology , vol.60 , pp. 601-617
    • King, K.L.1    Cidlowski, J.A.2
  • 113
    • 0027212380 scopus 로고
    • Regions of the retinoblastoma gene product required for its interaction with the E2F transcription factor are necessary for E2 promoter repression and pRb-mediated growth suppression
    • 1:CAS:528:DyaK3sXks1CrtLc%3D 8497257
    • SW Hiebert 1993 Regions of the retinoblastoma gene product required for its interaction with the E2F transcription factor are necessary for E2 promoter repression and pRb-mediated growth suppression Molecular and Cellular Biology 13 3384 3391 1:CAS:528:DyaK3sXks1CrtLc%3D 8497257
    • (1993) Molecular and Cellular Biology , vol.13 , pp. 3384-3391
    • Hiebert, S.W.1
  • 114
    • 0026440512 scopus 로고
    • Biological function of the retinoblastoma protein requires distinct domains for hyperphosphorylation and transcription factor binding
    • 1:CAS:528:DyaK3sXnvVagtg%3D%3D 1448071
    • Y Qian C Luckey L Horton M Esser DJ Templeton 1992 Biological function of the retinoblastoma protein requires distinct domains for hyperphosphorylation and transcription factor binding Molecular and Cellular Biology 12 5363 5372 1:CAS:528:DyaK3sXnvVagtg%3D%3D 1448071
    • (1992) Molecular and Cellular Biology , vol.12 , pp. 5363-5372
    • Qian, Y.1    Luckey, C.2    Horton, L.3    Esser, M.4    Templeton, D.J.5
  • 115
    • 0026648086 scopus 로고
    • Identification of a growth suppression domain within the retinoblastoma gene product
    • 1:CAS:528:DyaK38XksVejsLg%3D 10.1101/gad.6.6.953
    • XQ Qin T Chittenden DM Livingston WG Kaelin Jr 1992 Identification of a growth suppression domain within the retinoblastoma gene product Genes & Development 6 953 964 1:CAS:528:DyaK38XksVejsLg%3D 10.1101/gad.6.6.953
    • (1992) Genes & Development , vol.6 , pp. 953-964
    • Qin, X.Q.1    Chittenden, T.2    Livingston, D.M.3    Kaelin Jr., W.G.4
  • 116
    • 0025871150 scopus 로고
    • TIS10, a phorbol ester tumor promoter-inducible mRNA from Swiss 3 T3 cells, encodes a novel prostaglandin synthase/cyclooxygenase homologue
    • 1:CAS:528:DyaK38Xhs1Ontbk%3D 1712772
    • DA Kujubu BS Fletcher BC Varnum RW Lim HR Herschman 1991 TIS10, a phorbol ester tumor promoter-inducible mRNA from Swiss 3 T3 cells, encodes a novel prostaglandin synthase/cyclooxygenase homologue The Journal of Biological Chemistry 266 12866 12872 1:CAS:528:DyaK38Xhs1Ontbk%3D 1712772
    • (1991) The Journal of Biological Chemistry , vol.266 , pp. 12866-12872
    • Kujubu, D.A.1    Fletcher, B.S.2    Varnum, B.C.3    Lim, R.W.4    Herschman, H.R.5
  • 117
    • 0025365504 scopus 로고
    • Cyclooxygenase is an immediate-early gene induced by interleukin-1 in human endothelial cells
    • 1:CAS:528:DyaK3cXkslKgs7w%3D 1694171
    • JA Maier T Hla T Maciag 1990 Cyclooxygenase is an immediate-early gene induced by interleukin-1 in human endothelial cells The Journal of Biological Chemistry 265 10805 10808 1:CAS:528:DyaK3cXkslKgs7w%3D 1694171
    • (1990) The Journal of Biological Chemistry , vol.265 , pp. 10805-10808
    • Maier, J.A.1    Hla, T.2    MacIag, T.3
  • 118
    • 0028344102 scopus 로고
    • Regulation of eicosanoid production and mitogenesis in rat intestinal epithelial cells by transforming growth factor-alpha and phorbol ester
    • 1:CAS:528:DyaK2cXltVSmtrw%3D 8113389 10.1172/JCI116998
    • RN DuBois J Awad J Morrow LJ Roberts 2nd PR Bishop 1994 Regulation of eicosanoid production and mitogenesis in rat intestinal epithelial cells by transforming growth factor-alpha and phorbol ester Journal of Clinical Investigation 93 493 498 1:CAS:528:DyaK2cXltVSmtrw%3D 8113389 10.1172/JCI116998
    • (1994) Journal of Clinical Investigation , vol.93 , pp. 493-498
    • Dubois, R.N.1    Awad, J.2    Morrow, J.3    Roberts II, L.J.4    Bishop, P.R.5
  • 119
    • 0027468941 scopus 로고
    • Molecular cloning of human prostaglandin endoperoxide synthase type II and demonstration of expression in response to cytokines
    • 1:CAS:528:DyaK3sXks1Kntb4%3D 8473346
    • DA Jones DP Carlton TM McIntyre GA Zimmerman SM Prescott 1993 Molecular cloning of human prostaglandin endoperoxide synthase type II and demonstration of expression in response to cytokines The Journal of Biological Chemistry 268 9049 9054 1:CAS:528:DyaK3sXks1Kntb4%3D 8473346
    • (1993) The Journal of Biological Chemistry , vol.268 , pp. 9049-9054
    • Jones, D.A.1    Carlton, D.P.2    McIntyre, T.M.3    Zimmerman, G.A.4    Prescott, S.M.5
  • 120
    • 0037307483 scopus 로고    scopus 로고
    • Cyclooxygenase 2: A molecular target for cancer prevention and treatment
    • DOI 10.1016/S0165-6147(02)00043-3, PII S0165614702000433
    • K Subbaramaiah AJ Dannenberg 2003 Cyclooxygenase 2: A molecular target for cancer prevention and treatment Trends in Pharmacological Sciences 24 96 102 1:CAS:528:DC%2BD3sXmt1aktA%3D%3D 12559775 10.1016/S0165-6147(02)00043-3 (Pubitemid 36135884)
    • (2003) Trends in Pharmacological Sciences , vol.24 , Issue.2 , pp. 96-102
    • Subbaramaiah, K.1    Dannenberg, A.J.2
  • 121
    • 0035468642 scopus 로고    scopus 로고
    • Cyclo-oxygenase 2: A pharmacological target for the prevention of cancer
    • DOI 10.1016/S1470-2045(01)00488-0, PII S1470204501004880
    • AJ Dannenberg NK Altorki JO Boyle C Dang LR Howe BB Weksler, et al. 2001 Cyclo-oxygenase 2: A pharmacological target for the prevention of cancer The Lancet Oncology 2 544 551 1:CAS:528:DC%2BD3MXntFCnu7o%3D 11905709 10.1016/S1470-2045(01)00488-0 (Pubitemid 33586867)
    • (2001) Lancet Oncology , vol.2 , Issue.9 , pp. 544-551
    • Dannenberg, A.J.1    Altorki, N.K.2    Boyle, J.O.3    Dang, C.4    Howe, L.R.5    Weksler, B.B.6
  • 122
    • 33747099596 scopus 로고    scopus 로고
    • Acetyl-keto-β-boswellic acid inhibits cellular proliferation through a p21-dependent pathway in colon cancer cells
    • DOI 10.1038/sj.bjp.0706817, PII 0706817
    • JJ Liu B Huang SC Hooi 2006 Acetyl-keto-beta-boswellic acid inhibits cellular proliferation through a p21-dependent pathway in colon cancer cells British Journal of Pharmacology 148 1099 1107 1:CAS:528:DC%2BD28XotVylsLs%3D 16783403 10.1038/sj.bjp.0706817 (Pubitemid 44223016)
    • (2006) British Journal of Pharmacology , vol.148 , Issue.8 , pp. 1099-1107
    • Liu, J.-J.1    Huang, B.2    Hooi, S.C.3
  • 123
    • 40949089710 scopus 로고    scopus 로고
    • (1'S)-Acetoxychavicol acetate and its enantiomer inhibit tumor cells proliferation via different mechanisms
    • 1:CAS:528:DC%2BD1cXktVCks7o%3D 18281026 10.1016/j.cbi.2008.01.002
    • S Xu A Kojima-Yuasa H Azuma X Huang T Norikura DO Kennedy, et al. 2008 (1'S)-Acetoxychavicol acetate and its enantiomer inhibit tumor cells proliferation via different mechanisms Chem Biol Interact 172 216 223 1:CAS:528:DC%2BD1cXktVCks7o%3D 18281026 10.1016/j.cbi.2008.01.002
    • (2008) Chem Biol Interact , vol.172 , pp. 216-223
    • Xu, S.1    Kojima-Yuasa, A.2    Azuma, H.3    Huang, X.4    Norikura, T.5    Kennedy, D.O.6
  • 124
    • 33746047529 scopus 로고    scopus 로고
    • waf1/cip1 in colon cancer cells
    • DOI 10.1158/1535-7163.MCT-05-0495
    • JM Patlolla J Raju MV Swamy CV Rao 2006 Beta-escin inhibits colonic aberrant crypt foci formation in rats and regulates the cell cycle growth by inducing p21(waf1/cip1) in colon cancer cells Molecular Cancer Therapeutics 5 1459 1466 1:CAS:528:DC%2BD28XmsVamsrc%3D 16818504 10.1158/1535-7163.MCT-05-0495 (Pubitemid 44070482)
    • (2006) Molecular Cancer Therapeutics , vol.5 , Issue.6 , pp. 1459-1466
    • Patlolla, J.M.R.1    Raju, J.2    Swamy, M.V.3    Rao, C.V.4
  • 125
    • 76249092901 scopus 로고    scopus 로고
    • Curcumin suppresses proliferation and invasion in human gastric cancer cells by downregulation of PAK1 activity and cyclin D1 expression
    • 1:CAS:528:DC%2BC3cXisFKku7c%3D
    • XZ Cai J Wang XD Li GL Wang FN Liu MS Cheng, et al. 2009 Curcumin suppresses proliferation and invasion in human gastric cancer cells by downregulation of PAK1 activity and cyclin D1 expression Cancer Biology & Therapy 8 1360 1368 1:CAS:528:DC%2BC3cXisFKku7c%3D
    • (2009) Cancer Biology & Therapy , vol.8 , pp. 1360-1368
    • Cai, X.Z.1    Wang, J.2    Li, X.D.3    Wang, G.L.4    Liu, F.N.5    Cheng, M.S.6
  • 126
    • 74049162893 scopus 로고    scopus 로고
    • Deguelin inhibits growth of breast cancer cells by modulating the expression of key members of the Wnt signaling pathway
    • 1:CAS:528:DC%2BC3cXptVyrsbY%3D
    • G Murillo X Peng KE Torres RG Mehta 2009 Deguelin inhibits growth of breast cancer cells by modulating the expression of key members of the Wnt signaling pathway Cancer Prevention Research (Philadelphia, PA) 2 942 950 1:CAS:528:DC%2BC3cXptVyrsbY%3D
    • (2009) Cancer Prevention Research (Philadelphia, PA) , vol.2 , pp. 942-950
    • Murillo, G.1    Peng, X.2    Torres, K.E.3    Mehta, R.G.4
  • 127
    • 0037031787 scopus 로고    scopus 로고
    • The antiproliferative activity of aloe-emodin is through p53-dependent and p21-dependent apoptotic pathway in human hepatoma cell lines
    • 1:CAS:528:DC%2BD38XlvF2rsLc%3D 12175703 10.1016/S0024-3205(02)01900-8
    • PL Kuo TC Lin CC Lin 2002 The antiproliferative activity of aloe-emodin is through p53-dependent and p21-dependent apoptotic pathway in human hepatoma cell lines Life Sciences 71 1879 1892 1:CAS:528:DC%2BD38XlvF2rsLc%3D 12175703 10.1016/S0024-3205(02)01900-8
    • (2002) Life Sciences , vol.71 , pp. 1879-1892
    • Kuo, P.L.1    Lin, T.C.2    Lin, C.C.3
  • 128
    • 47249134657 scopus 로고    scopus 로고
    • Fisetin, a novel dietary flavonoid, causes apoptosis and cell cycle arrest in human prostate cancer LNCaP cells
    • DOI 10.1093/carcin/bgn078
    • N Khan F Afaq DN Syed H Mukhtar 2008 Fisetin, a novel dietary flavonoid, causes apoptosis and cell cycle arrest in human prostate cancer LNCaP cells Carcinogenesis 29 1049 1056 1:CAS:528:DC%2BD1cXot1Wgu7s%3D 18359761 10.1093/carcin/bgn078 (Pubitemid 351982251)
    • (2008) Carcinogenesis , vol.29 , Issue.5 , pp. 1049-1056
    • Khan, N.1    Afaq, F.2    Syed, D.N.3    Mukhtar, H.4
  • 129
    • 70349970798 scopus 로고    scopus 로고
    • Piceatannol, a natural stilbene from grapes, induces G1 cell cycle arrest in androgen-insensitive DU145 human prostate cancer cells via the inhibition of CDK activity
    • 1:CAS:528:DC%2BD1MXht1OgtbzP 19487074 10.1016/j.canlet.2009.05.011
    • YM Lee DY Lim HJ Cho MR Seon JK Kim BY Lee, et al. 2009 Piceatannol, a natural stilbene from grapes, induces G1 cell cycle arrest in androgen-insensitive DU145 human prostate cancer cells via the inhibition of CDK activity Cancer Letters 285 166 173 1:CAS:528:DC%2BD1MXht1OgtbzP 19487074 10.1016/j.canlet.2009.05.011
    • (2009) Cancer Letters , vol.285 , pp. 166-173
    • Lee, Y.M.1    Lim, D.Y.2    Cho, H.J.3    Seon, M.R.4    Kim, J.K.5    Lee, B.Y.6
  • 130
    • 77949907818 scopus 로고    scopus 로고
    • Silibinin inhibits human nonsmall cell lung cancer cell growth through cell-cycle arrest by modulating expression and function of key cell-cycle regulators
    • 1:CAS:528:DC%2BC3cXitF2ks7c%3D 19908243
    • S Mateen A Tyagi C Agarwal RP Singh R Agarwal 2010 Silibinin inhibits human nonsmall cell lung cancer cell growth through cell-cycle arrest by modulating expression and function of key cell-cycle regulators Molecular Carcinogenesis 49 247 258 1:CAS:528:DC%2BC3cXitF2ks7c%3D 19908243
    • (2010) Molecular Carcinogenesis , vol.49 , pp. 247-258
    • Mateen, S.1    Tyagi, A.2    Agarwal, C.3    Singh, R.P.4    Agarwal, R.5
  • 131
    • 34548015409 scopus 로고    scopus 로고
    • Androgen receptor- and E2F-1-targeted thymoquinone therapy for hormone-refractory prostate cancer
    • DOI 10.1158/0008-5472.CAN-07-1483
    • AO Kaseb K Chinnakannu D Chen A Sivanandam S Tejwani M Menon, et al. 2007 Androgen receptor and E2F-1 targeted thymoquinone therapy for hormone-refractory prostate cancer Cancer Research 67 7782 7788 1:CAS:528:DC%2BD2sXptVGltrw%3D 17699783 10.1158/0008-5472.CAN-07-1483 (Pubitemid 47281372)
    • (2007) Cancer Research , vol.67 , Issue.16 , pp. 7782-7788
    • Kaseb, A.O.1    Chinnakannu, K.2    Chen, D.3    Sivanandam, A.4    Tejwani, S.5    Menon, M.6    Dou, Q.P.7    Reddy, G.P.-V.8
  • 132
    • 34547974814 scopus 로고    scopus 로고
    • Dietary quercetin inhibits proliferation of lung carcinoma cells
    • 1:CAS:528:DC%2BD1MXltFehtbY%3D 17684411 10.1159/000107165
    • H Hung 2007 Dietary quercetin inhibits proliferation of lung carcinoma cells Forum of Nutrition 60 146 157 1:CAS:528:DC%2BD1MXltFehtbY%3D 17684411 10.1159/000107165
    • (2007) Forum of Nutrition , vol.60 , pp. 146-157
    • Hung, H.1
  • 133
    • 77950552489 scopus 로고    scopus 로고
    • Sulforaphane induces cell cycle arrest by protecting RB-E2F-1 complex in epithelial ovarian cancer cells
    • 20196847 10.1186/1476-4598-9-47 1:CAS:528:DC%2BC3cXivFOhu7s%3D
    • CS Bryant S Kumar S Chamala J Shah J Pal M Haider, et al. 2010 Sulforaphane induces cell cycle arrest by protecting RB-E2F-1 complex in epithelial ovarian cancer cells Molecular Cancer 9 47 20196847 10.1186/1476-4598-9-47 1:CAS:528:DC%2BC3cXivFOhu7s%3D
    • (2010) Molecular Cancer , vol.9 , pp. 47
    • Bryant, C.S.1    Kumar, S.2    Chamala, S.3    Shah, J.4    Pal, J.5    Haider, M.6
  • 134
    • 74849131331 scopus 로고    scopus 로고
    • Butein induces G(2)/M phase arrest and apoptosis in human hepatoma cancer cells through ROS generation
    • 1:CAS:528:DC%2BC3cXhtlSjurc%3D 19643530 10.1016/j.canlet.2009.07.002
    • DO Moon MO Kim YH Choi JW Hyun WY Chang GY Kim 2010 Butein induces G(2)/M phase arrest and apoptosis in human hepatoma cancer cells through ROS generation Cancer Letters 288 204 213 1:CAS:528:DC%2BC3cXhtlSjurc%3D 19643530 10.1016/j.canlet.2009.07.002
    • (2010) Cancer Letters , vol.288 , pp. 204-213
    • Moon, D.O.1    Kim, M.O.2    Choi, Y.H.3    Hyun, J.W.4    Chang, W.Y.5    Kim, G.Y.6
  • 135
    • 77949454738 scopus 로고    scopus 로고
    • Celastrol causes apoptosis and cell cycle arrest in rat glioma cells
    • 1:CAS:528:DC%2BC3cXjtFOnsLs%3D 19909582 10.1179/016164109X12518779082273
    • P Ge X Ji Y Ding X Wang S Fu F Meng, et al. 2010 Celastrol causes apoptosis and cell cycle arrest in rat glioma cells Neurological Research 32 94 100 1:CAS:528:DC%2BC3cXjtFOnsLs%3D 19909582 10.1179/016164109X12518779082273
    • (2010) Neurological Research , vol.32 , pp. 94-100
    • Ge, P.1    Ji, X.2    Ding, Y.3    Wang, X.4    Fu, S.5    Meng, F.6
  • 136
    • 77955474313 scopus 로고    scopus 로고
    • Anti-proliferative effects of evodiamine on human thyroid cancer cell line ARO
    • 1:CAS:528:DC%2BC3cXovFKqsrs%3D 20503248 10.1002/jcb.22716
    • MC Chen CH Yu SW Wang HF Pu SF Kan LC Lin, et al. 2010 Anti-proliferative effects of evodiamine on human thyroid cancer cell line ARO Journal of Cellular Biochemistry 110 1495 1503 1:CAS:528:DC%2BC3cXovFKqsrs%3D 20503248 10.1002/jcb.22716
    • (2010) Journal of Cellular Biochemistry , vol.110 , pp. 1495-1503
    • Chen, M.C.1    Yu, C.H.2    Wang, S.W.3    Pu, H.F.4    Kan, S.F.5    Lin, L.C.6
  • 137
    • 77954761399 scopus 로고    scopus 로고
    • Gambogic acid triggers DNA damage signaling that induces p53/p21(Waf1/CIP1) activation through the ATR-Chk1 pathway
    • 1:CAS:528:DC%2BC3cXovFymsbo%3D 20413215 10.1016/j.canlet.2010.03.016
    • JJ Rong R Hu XM Song J Ha N Lu Q Qi, et al. 2010 Gambogic acid triggers DNA damage signaling that induces p53/p21(Waf1/CIP1) activation through the ATR-Chk1 pathway Cancer Letters 296 55 64 1:CAS:528:DC%2BC3cXovFymsbo%3D 20413215 10.1016/j.canlet.2010.03.016
    • (2010) Cancer Letters , vol.296 , pp. 55-64
    • Rong, J.J.1    Hu, R.2    Song, X.M.3    Ha, J.4    Lu, N.5    Qi, Q.6
  • 138
    • 74549125417 scopus 로고    scopus 로고
    • Effect of betulinic acid on the regulation of Hiwi and cyclin B1 in human gastric adenocarcinoma AGS cells
    • 1:CAS:528:DC%2BC3cXptF2j 20037601 10.1038/aps.2009.177
    • LJ Yang Y Chen Q Ma J Fang J He YQ Cheng, et al. 2010 Effect of betulinic acid on the regulation of Hiwi and cyclin B1 in human gastric adenocarcinoma AGS cells Acta Pharmacologica Sinica 31 66 72 1:CAS:528:DC%2BC3cXptF2j 20037601 10.1038/aps.2009.177
    • (2010) Acta Pharmacologica Sinica , vol.31 , pp. 66-72
    • Yang, L.J.1    Chen, Y.2    Ma, Q.3    Fang, J.4    He, J.5    Cheng, Y.Q.6
  • 139
    • 33751332527 scopus 로고    scopus 로고
    • Zerumbone, a bioactive sesquiterpene, induces G2/M cell cycle arrest and apoptosis in leukemia cells via a Fas- and mitochondria-mediated pathway
    • DOI 10.1111/j.1349-7006.2006.00362.x
    • M Xian K Ito T Nakazato T Shimizu CK Chen K Yamato, et al. 2007 Zerumbone, a bioactive sesquiterpene, induces G2/M cell cycle arrest and apoptosis in leukemia cells via a Fas- and mitochondria-mediated pathway Cancer Science 98 118 126 1:CAS:528:DC%2BD2sXht1Gitrs%3D 17129359 10.1111/j.1349-7006. 2006.00362.x (Pubitemid 44803930)
    • (2007) Cancer Science , vol.98 , Issue.1 , pp. 118-126
    • Xian, M.1    Ito, K.2    Nakazato, T.3    Shimizu, T.4    Chen, C.-K.5    Yamato, K.6    Murakami, A.7    Ohigashi, H.8    Ikeda, Y.9    Kizaki, M.10
  • 140
    • 60449106119 scopus 로고    scopus 로고
    • Berberine induces p53-dependent cell cycle arrest and apoptosis of human osteosarcoma cells by inflicting DNA damage
    • 1:CAS:528:DC%2BD1MXisFWqu7s%3D 19159633
    • Z Liu Q Liu B Xu J Wu C Guo F Zhu, et al. 2009 Berberine induces p53-dependent cell cycle arrest and apoptosis of human osteosarcoma cells by inflicting DNA damage Mutation Research 662 75 83 1:CAS:528:DC%2BD1MXisFWqu7s%3D 19159633
    • (2009) Mutation Research , vol.662 , pp. 75-83
    • Liu, Z.1    Liu, Q.2    Xu, B.3    Wu, J.4    Guo, C.5    Zhu, F.6
  • 141
    • 34249058341 scopus 로고    scopus 로고
    • Guggulsterone inhibits tumor cell proliferation, induces S-phase arrest, and promotes apoptosis through activation of c-Jun N-terminal kinase, suppression of Akt pathway, and downregulation of antiapoptotic gene products
    • DOI 10.1016/j.bcp.2007.03.026, PII S0006295207001955
    • S Shishodia G Sethi KS Ahn BB Aggarwal 2007 Guggulsterone inhibits tumor cell proliferation, induces S-phase arrest, and promotes apoptosis through activation of c-Jun N-terminal kinase, suppression of Akt pathway, and downregulation of antiapoptotic gene products Biochemical Pharmacology 74 118 130 1:CAS:528:DC%2BD2sXlvV2qtb4%3D 17475222 10.1016/j.bcp.2007.03.026 (Pubitemid 46802496)
    • (2007) Biochemical Pharmacology , vol.74 , Issue.1 , pp. 118-130
    • Shishodia, S.1    Sethi, G.2    Ahn, K.S.3    Aggarwal, B.B.4
  • 143
    • 69849091814 scopus 로고    scopus 로고
    • Curcumin inhibits cell proliferation of MDA-MB-231 and BT-483 breast cancer cells mediated by down-regulation of NFkappaB, cyclinD and MMP-1 transcription
    • 1:CAS:528:DC%2BD1MXhtlKqt73F 19524420 10.1016/j.phymed.2009.04.008
    • Q Liu WT Loo SC Sze Y Tong 2009 Curcumin inhibits cell proliferation of MDA-MB-231 and BT-483 breast cancer cells mediated by down-regulation of NFkappaB, cyclinD and MMP-1 transcription Phytomedicine 16 916 922 1:CAS:528:DC%2BD1MXhtlKqt73F 19524420 10.1016/j.phymed.2009.04.008
    • (2009) Phytomedicine , vol.16 , pp. 916-922
    • Liu, Q.1    Loo, W.T.2    Sze, S.C.3    Tong, Y.4
  • 144
    • 60149112516 scopus 로고    scopus 로고
    • A plant flavonoid fisetin induces apoptosis in colon cancer cells by inhibition of COX2 and Wnt/EGFR/NF-kappaB-signaling pathways
    • 1:CAS:528:DC%2BD1MXhs1ansrw%3D 19037088 10.1093/carcin/bgn269
    • Y Suh F Afaq JJ Johnson H Mukhtar 2009 A plant flavonoid fisetin induces apoptosis in colon cancer cells by inhibition of COX2 and Wnt/EGFR/NF-kappaB- signaling pathways Carcinogenesis 30 300 307 1:CAS:528:DC%2BD1MXhs1ansrw%3D 19037088 10.1093/carcin/bgn269
    • (2009) Carcinogenesis , vol.30 , pp. 300-307
    • Suh, Y.1    Afaq, F.2    Johnson, J.J.3    Mukhtar, H.4
  • 145
    • 33644840279 scopus 로고    scopus 로고
    • Diosgenin inhibits osteoclastogenesis, invasion, and proliferation through the downregulation of Akt, IκB kinase activation and NF-κB-regulated gene expression
    • DOI 10.1038/sj.onc.1209194, PII 1209194
    • S Shishodia BB Aggarwal 2006 Diosgenin inhibits osteoclastogenesis, invasion, and proliferation through the downregulation of Akt, I kappa B kinase activation and NF-kappa B-regulated gene expression Oncogene 25 1463 1473 1:CAS:528:DC%2BD28XitFGht78%3D 16331273 10.1038/sj.onc.1209194 (Pubitemid 43361932)
    • (2006) Oncogene , vol.25 , Issue.10 , pp. 1463-1473
    • Shishodia, S.1    Aggarwal, B.B.2
  • 146
    • 34247477985 scopus 로고    scopus 로고
    • Morin (3,5,7,2′,4′-pentahydroxyflavone) abolishes nuclear factor-κB activation induced by various carcinogens and inflammatory stimuli, leading to suppression of nuclear factor-κB - Regulated gene expression and up-regulation of apoptosis
    • DOI 10.1158/1078-0432.CCR-06-2394
    • SK Manna RS Aggarwal G Sethi BB Aggarwal GT Ramesh 2007 Morin (3, 5, 7, 2', 4'-pentahydroxyflavone) abolishes nuclear factor-kappaB activation induced by various carcinogens and inflammatory stimuli, leading to suppression of nuclear factor-kappaB-regulated gene expression and up-regulation of apoptosis Clinical Cancer Research 13 2290 2297 1:CAS:528:DC%2BD2sXjs12rtbs%3D 17404114 10.1158/1078-0432.CCR-06-2394 (Pubitemid 46649899)
    • (2007) Clinical Cancer Research , vol.13 , Issue.7 , pp. 2290-2297
    • Manna, S.K.1    Aggarwal, R.S.2    Sethi, G.3    Aggarwal, B.B.4    Ramesh, G.T.5
  • 147
    • 49849102561 scopus 로고    scopus 로고
    • Pinitol targets nuclear factor-kappaB activation pathway leading to inhibition of gene products associated with proliferation, apoptosis, invasion, and angiogenesis
    • 1:CAS:528:DC%2BD1cXnsVSktbo%3D 18566231 10.1158/1535-7163.MCT-07-2424
    • G Sethi KS Ahn B Sung BB Aggarwal 2008 Pinitol targets nuclear factor-kappaB activation pathway leading to inhibition of gene products associated with proliferation, apoptosis, invasion, and angiogenesis Molecular Cancer Therapeutics 7 1604 1614 1:CAS:528:DC%2BD1cXnsVSktbo%3D 18566231 10.1158/1535-7163.MCT-07-2424
    • (2008) Molecular Cancer Therapeutics , vol.7 , pp. 1604-1614
    • Sethi, G.1    Ahn, K.S.2    Sung, B.3    Aggarwal, B.B.4
  • 148
    • 0042090509 scopus 로고    scopus 로고
    • Ursolic acid inhibits nuclear factor-kappaB activation induced by carcinogenic agents through suppression of IkappaBalpha kinase and p65 phosphorylation: Correlation with down-regulation of cyclooxygenase 2, matrix metalloproteinase 9, and cyclin D1
    • 1:CAS:528:DC%2BD3sXmtFeku70%3D 12907607
    • S Shishodia S Majumdar S Banerjee BB Aggarwal 2003 Ursolic acid inhibits nuclear factor-kappaB activation induced by carcinogenic agents through suppression of IkappaBalpha kinase and p65 phosphorylation: Correlation with down-regulation of cyclooxygenase 2, matrix metalloproteinase 9, and cyclin D1 Cancer Research 63 4375 4383 1:CAS:528:DC%2BD3sXmtFeku70%3D 12907607
    • (2003) Cancer Research , vol.63 , pp. 4375-4383
    • Shishodia, S.1    Majumdar, S.2    Banerjee, S.3    Aggarwal, B.B.4
  • 149
    • 34250715970 scopus 로고    scopus 로고
    • A bioactive withanolide Tubocapsanolide A inhibits proliferation of human lung cancer cells via repressing Skp2 expression
    • DOI 10.1158/1535-7163.MCT-06-0812
    • HC Chang FR Chang YC Wang MR Pan WC Hung YC Wu 2007 A bioactive withanolide Tubocapsanolide A inhibits proliferation of human lung cancer cells via repressing Skp2 expression Molecular Cancer Therapeutics 6 1572 1578 1:CAS:528:DC%2BD2sXotFaltLk%3D 17513606 10.1158/1535-7163.MCT-06-0812 (Pubitemid 46954024)
    • (2007) Molecular Cancer Therapeutics , vol.6 , Issue.5 , pp. 1572-1578
    • Chang, H.-C.1    Chang, F.-R.2    Wang, Y.-C.3    Pan, M.-R.4    Hung, W.-C.5    Wu, Y.-C.6
  • 150
    • 77956314277 scopus 로고    scopus 로고
    • Capsaicin displays anti-proliferative activity against human small cell lung cancer in cell culture and nude mice models via the E2F pathway
    • 20421925 10.1371/journal.pone.0010243 1:CAS:528:DC%2BC3cXlsVymsLg%3D
    • KC Brown TR Witte WE Hardman H Luo YC Chen AB Carpenter, et al. 2010 Capsaicin displays anti-proliferative activity against human small cell lung cancer in cell culture and nude mice models via the E2F pathway PloS One 5 e10243 20421925 10.1371/journal.pone.0010243 1:CAS:528:DC%2BC3cXlsVymsLg%3D
    • (2010) PloS One , vol.5 , pp. 10243
    • Brown, K.C.1    Witte, T.R.2    Hardman, W.E.3    Luo, H.4    Chen, Y.C.5    Carpenter, A.B.6
  • 151
    • 67649559317 scopus 로고    scopus 로고
    • Gossypol inhibits the growth of MAT-LyLu prostate cancer cells by modulation of TGFbeta/Akt signaling
    • 19513537
    • J Jiang W Ye YC Lin 2009 Gossypol inhibits the growth of MAT-LyLu prostate cancer cells by modulation of TGFbeta/Akt signaling International Journal of Molecular Medicine 24 69 75 19513537
    • (2009) International Journal of Molecular Medicine , vol.24 , pp. 69-75
    • Jiang, J.1    Ye, W.2    Lin, Y.C.3
  • 152
    • 0029805716 scopus 로고    scopus 로고
    • Genistein inhibits both estrogen and growth factor-stimulated proliferation of human breast cancer cells
    • 1:CAS:528:DyaK28Xmt1Cis74%3D
    • G Peterson S Barnes 1996 Genistein inhibits both estrogen and growth factor-stimulated proliferation of human breast cancer cells Cell Growth & Differentiation 7 1345 1351 1:CAS:528:DyaK28Xmt1Cis74%3D
    • (1996) Cell Growth & Differentiation , vol.7 , pp. 1345-1351
    • Peterson, G.1    Barnes, S.2
  • 153
    • 0027194978 scopus 로고
    • Genistein and biochanin A inhibit the growth of human prostate cancer cells but not epidermal growth factor receptor tyrosine autophosphorylation
    • 1:CAS:528:DyaK3sXltlWjt78%3D 8497428 10.1002/pros.2990220408
    • G Peterson S Barnes 1993 Genistein and biochanin A inhibit the growth of human prostate cancer cells but not epidermal growth factor receptor tyrosine autophosphorylation The Prostate 22 335 345 1:CAS:528:DyaK3sXltlWjt78%3D 8497428 10.1002/pros.2990220408
    • (1993) The Prostate , vol.22 , pp. 335-345
    • Peterson, G.1    Barnes, S.2
  • 154
    • 0025363503 scopus 로고
    • Induction of differentiation and DNA strand breakage in human HL-60 and K-562 leukemia cells by genistein
    • A Constantinou K Kiguchi E Huberman 1990 Induction of differentiation and DNA strand breakage in human HL-60 and K-562 leukemia cells by genistein Cancer Research 50 2618 2624 1:CAS:528:DyaK3cXit12nsL4%3D 2158395 (Pubitemid 20150193)
    • (1990) Cancer Research , vol.50 , Issue.9 , pp. 2618-2624
    • Constantinou, A.1    Kiguchi, K.2    Huberman, E.3
  • 155
    • 0027772877 scopus 로고
    • Inhibition by genistein of prolactin-induced Nb2 lymphoma cell mitogenesis
    • DOI 10.1016/0303-7207(93)90231-8
    • AR Buckley DJ Buckley PW Gout H Liang YP Rao MJ Blake 1993 Inhibition by genistein of prolactin-induced Nb2 lymphoma cell mitogenesis Molecular and Cellular Endocrinology 98 17 25 1:CAS:528:DyaK2cXps1entg%3D%3D 8143910 10.1016/0303-7207(93)90231-8 (Pubitemid 24016924)
    • (1993) Molecular and Cellular Endocrinology , vol.98 , Issue.1 , pp. 17-25
    • Buckley, A.R.1    Buckley, D.J.2    Gout, P.W.3    Liang, H.4    Rao -p., Y.5    Blake, M.J.6
  • 156
    • 0027479424 scopus 로고
    • Genistein arrests cell cycle progression at G2-M
    • 1:CAS:528:DyaK3sXksVSgu7s%3D 8443813
    • Y Matsukawa N Marui T Sakai Y Satomi M Yoshida K Matsumoto, et al. 1993 Genistein arrests cell cycle progression at G2-M Cancer Research 53 1328 1331 1:CAS:528:DyaK3sXksVSgu7s%3D 8443813
    • (1993) Cancer Research , vol.53 , pp. 1328-1331
    • Matsukawa, Y.1    Marui, N.2    Sakai, T.3    Satomi, Y.4    Yoshida, M.5    Matsumoto, K.6
  • 158
    • 0034631517 scopus 로고    scopus 로고
    • P21(CIP1) is dispensable for the G2 arrest caused by genistein in human melanoma cells
    • DOI 10.1006/excr.2000.4914
    • F Casagrande JM Darbon 2000 p21CIP1 is dispensable for the G2 arrest caused by genistein in human melanoma cells Experimental Cell Research 258 101 108 1:CAS:528:DC%2BD3cXkt1Kgs7s%3D 10912792 10.1006/excr.2000.4914 (Pubitemid 30461112)
    • (2000) Experimental Cell Research , vol.258 , Issue.1 , pp. 101-108
    • Casagrande, F.1    Darbon, J.-M.2
  • 159
    • 0032500829 scopus 로고    scopus 로고
    • Genistein induces p21(Cip1/WAF1) expression and blocks the G1 to S phase transition in mouse fibroblast and melanoma cells
    • DOI 10.1006/bbrc.1998.9462
    • T Kuzumaki T Kobayashi K Ishikawa 1998 Genistein induces p21(Cip1/WAF1) expression and blocks the G1 to S phase transition in mouse fibroblast and melanoma cells Biochemical and Biophysical Research Communications 251 291 295 1:CAS:528:DyaK1cXmvFKitLY%3D 9790949 10.1006/bbrc.1998.9462 (Pubitemid 28498105)
    • (1998) Biochemical and Biophysical Research Communications , vol.251 , Issue.1 , pp. 291-295
    • Kuzumaki, T.1    Kobayashi, T.2    Ishikawa, K.3
  • 160
    • 0032456061 scopus 로고    scopus 로고
    • Genistein-induced upregulation of p21WAF1, downregulation of cyclin B, and induction of apoptosis in prostate cancer cells
    • 1:CAS:528:DyaK1MXhtlalsrg%3D 10050261 10.1080/01635589809514730
    • JN Davis B Singh M Bhuiyan FH Sarkar 1998 Genistein-induced upregulation of p21WAF1, downregulation of cyclin B, and induction of apoptosis in prostate cancer cells Nutrition and Cancer 32 123 131 1:CAS:528:DyaK1MXhtlalsrg%3D 10050261 10.1080/01635589809514730
    • (1998) Nutrition and Cancer , vol.32 , pp. 123-131
    • Davis, J.N.1    Singh, B.2    Bhuiyan, M.3    Sarkar, F.H.4
  • 161
    • 0031595611 scopus 로고    scopus 로고
    • 2-M arrest, p21(WAF1) upregulation, and apoptosis in a non-small-cell lung cancer cell line
    • F Lian M Bhuiyan YW Li N Wall M Kraut FH Sarkar 1998 Genistein-induced G2-M arrest, p21WAF1 upregulation, and apoptosis in a non-small-cell lung cancer cell line Nutrition and Cancer 31 184 191 1:CAS:528:DyaK1cXnt1ens7k%3D 9795970 10.1080/01635589809514701 (Pubitemid 28481852)
    • (1998) Nutrition and Cancer , vol.31 , Issue.3 , pp. 184-191
    • Lian, F.1    Bhuiyan, M.2    Li, Y.-W.3    Wall, N.4    Kraut, M.5    Sarkar, F.H.6
  • 162
    • 0033587157 scopus 로고    scopus 로고
    • Induction of apoptosis in breast cancer cells MDA-MB-231 by genistein
    • DOI 10.1038/sj.onc.1202650
    • Y Li S Upadhyay M Bhuiyan FH Sarkar 1999 Induction of apoptosis in breast cancer cells MDA-MB-231 by genistein Oncogene 18 3166 3172 1:CAS:528: DyaK1MXjs1Onu74%3D 10340389 10.1038/sj.onc.1202650 (Pubitemid 29261238)
    • (1999) Oncogene , vol.18 , Issue.20 , pp. 3166-3172
    • Li, Y.1    Upadhyay, S.2    Bhuiyan, M.3    Sarkar, F.H.4
  • 163
    • 0032864723 scopus 로고    scopus 로고
    • Genistein-induced cell cycle arrest and apoptosis in a head and neck squamous cell carcinoma cell line
    • 1:CAS:528:DyaK1MXlslyjsbw%3D 10453436 10.1207/S15327914NC340102
    • SA Alhasan H Pietrasczkiwicz MD Alonso J Ensley FH Sarkar 1999 Genistein-induced cell cycle arrest and apoptosis in a head and neck squamous cell carcinoma cell line Nutrition and Cancer 34 12 19 1:CAS:528: DyaK1MXlslyjsbw%3D 10453436 10.1207/S15327914NC340102
    • (1999) Nutrition and Cancer , vol.34 , pp. 12-19
    • Alhasan, S.A.1    Pietrasczkiwicz, H.2    Alonso, M.D.3    Ensley, J.4    Sarkar, F.H.5
  • 164
    • 33749053416 scopus 로고    scopus 로고
    • Identification of both Myt-1 and Wee-1 as necessary mediators of the p21-independent inactivation of the Cdc-2/cyclin B1 complex and growth inhibition of TRAMP cancer cells by genistein
    • DOI 10.1002/pros.20495
    • LH Touny PP Banerjee 2006 Identification of both Myt-1 and Wee-1 as necessary mediators of the p21-independent inactivation of the cdc-2/cyclin B1 complex and growth inhibition of TRAMP cancer cells by genistein The Prostate 66 1542 1555 16924665 10.1002/pros.20495 1:CAS:528:DC%2BD28XhtFWks7zF (Pubitemid 44465819)
    • (2006) Prostate , vol.66 , Issue.14 , pp. 1542-1555
    • El Touny, L.H.1    Banerjee, P.P.2
  • 165
    • 0035188727 scopus 로고    scopus 로고
    • How matrix metalloproteinases regulate cell behavior
    • DOI 10.1146/annurev.cellbio.17.1.463
    • MD Sternlicht Z Werb 2001 How matrix metalloproteinases regulate cell behavior Annual Review of Cell and Developmental Biology 17 463 516 1:CAS:528:DC%2BD3MXos1Omsbs%3D 11687497 10.1146/annurev.cellbio.17.1.463 (Pubitemid 33096184)
    • (2001) Annual Review of Cell and Developmental Biology , vol.17 , pp. 463-516
    • Sternlicht, M.D.1    Werb, Z.2
  • 166
    • 0034805565 scopus 로고    scopus 로고
    • Aspirin inhibits matrix metalloproteinase-2 activity, increases E-cadherin production, and inhibits in Vitro invasion of tumor cells
    • DOI 10.1006/bbrc.2001.4637
    • MC Jiang CF Liao PH Lee 2001 Aspirin inhibits matrix metalloproteinase-2 activity, increases E-cadherin production, and inhibits in vitro invasion of tumor cells Biochemical and Biophysical Research Communications 282 671 677 1:CAS:528:DC%2BD3MXitleisLg%3D 11401513 10.1006/bbrc.2001.4637 (Pubitemid 32924608)
    • (2001) Biochemical and Biophysical Research Communications , vol.282 , Issue.3 , pp. 671-677
    • Jiang, M.-C.1    Liao, C.-F.2    Lee, P.-H.3
  • 167
    • 0028947020 scopus 로고
    • Matrix metalloproteinase-2 is an interstitial collagenase. Inhibitor-free enzyme catalyzes the cleavage of collagen fibrils and soluble native type i collagen generating the specific 3/4- and 1/4-length fragments
    • 1:CAS:528:DyaK2MXksVCntrk%3D 7890717 10.1074/jbc.270.11.5872
    • RT Aimes JP Quigley 1995 Matrix metalloproteinase-2 is an interstitial collagenase. Inhibitor-free enzyme catalyzes the cleavage of collagen fibrils and soluble native type I collagen generating the specific 3/4- and 1/4-length fragments The Journal of Biological Chemistry 270 5872 5876 1:CAS:528: DyaK2MXksVCntrk%3D 7890717 10.1074/jbc.270.11.5872
    • (1995) The Journal of Biological Chemistry , vol.270 , pp. 5872-5876
    • Aimes, R.T.1    Quigley, J.P.2
  • 168
    • 0027683226 scopus 로고
    • Structural biochemistry and activation of matrix metalloproteases
    • 1:CAS:528:DyaK3sXmsVCjsr0%3D 8240832 10.1016/0955-0674(93)90040-W
    • DE Kleiner Jr WG Stetler-Stevenson 1993 Structural biochemistry and activation of matrix metalloproteases Current Opinion in Cell Biology 5 891 897 1:CAS:528:DyaK3sXmsVCjsr0%3D 8240832 10.1016/0955-0674(93)90040-W
    • (1993) Current Opinion in Cell Biology , vol.5 , pp. 891-897
    • Kleiner Jr., D.E.1    Stetler-Stevenson, W.G.2
  • 169
    • 0033039398 scopus 로고    scopus 로고
    • An odyssey from breast to bone: Multi-step control of mammary metastases and osteolysis by matrix metalloproteinases
    • 1:CAS:528:DyaK1MXitFalsL8%3D 10190289 10.1111/j.1699-0463.1999.tb01535.x
    • A Lochter MJ Bissell 1999 An odyssey from breast to bone: Multi-step control of mammary metastases and osteolysis by matrix metalloproteinases APMIS 107 128 136 1:CAS:528:DyaK1MXitFalsL8%3D 10190289 10.1111/j.1699-0463.1999. tb01535.x
    • (1999) APMIS , vol.107 , pp. 128-136
    • Lochter, A.1    Bissell, M.J.2
  • 170
    • 0031716731 scopus 로고    scopus 로고
    • Expression of metalloproteinases and their inhibitors in adenocarcinoma of the uterine cervix
    • 1:STN:280:DyaK1M%2FgtFejug%3D%3D 9785129 10.1097/00004347-199810000-00002
    • B Davidson I Goldberg P Liokumovich J Kopolovic WH Gotlieb L Lerner-Geva, et al. 1998 Expression of metalloproteinases and their inhibitors in adenocarcinoma of the uterine cervix International Journal of Gynecological Pathology 17 295 301 1:STN:280:DyaK1M%2FgtFejug%3D%3D 9785129 10.1097/00004347-199810000-00002
    • (1998) International Journal of Gynecological Pathology , vol.17 , pp. 295-301
    • Davidson, B.1    Goldberg, I.2    Liokumovich, P.3    Kopolovic, J.4    Gotlieb, W.H.5    Lerner-Geva, L.6
  • 171
    • 0345109257 scopus 로고    scopus 로고
    • Expression of metalloproteinase 2 and 9 and their inhibitors in renal cell carcinoma
    • 1:CAS:528:DyaK1cXmvFSlt74%3D 10.1016/S0022-5347(01)62443-1
    • A Kugler B Hemmerlein P Thelen M Kallerhoff HJ Radzun RH Ringert 1998 Expression of metalloproteinase 2 and 9 and their inhibitors in renal cell carcinoma Journal d'Urologie 160 1914 1918 1:CAS:528:DyaK1cXmvFSlt74%3D 10.1016/S0022-5347(01)62443-1
    • (1998) Journal d'Urologie , vol.160 , pp. 1914-1918
    • Kugler, A.1    Hemmerlein, B.2    Thelen, P.3    Kallerhoff, M.4    Radzun, H.J.5    Ringert, R.H.6
  • 172
    • 0008427936 scopus 로고    scopus 로고
    • Expression of matrix metalloproteinase-7 and tissue inhibitor of metalloproteinase-1 in human prostate
    • 1:CAS:528:DyaK1cXmvFSls7Y%3D 10.1016/S0022-5347(01)62435-2
    • K Hashimoto Y Kihira Y Matuo T Usui 1998 Expression of matrix metalloproteinase-7 and tissue inhibitor of metalloproteinase-1 in human prostate Journal d'Urologie 160 1872 1876 1:CAS:528:DyaK1cXmvFSls7Y%3D 10.1016/S0022-5347(01)62435-2
    • (1998) Journal d'Urologie , vol.160 , pp. 1872-1876
    • Hashimoto, K.1    Kihira, Y.2    Matuo, Y.3    Usui, T.4
  • 173
    • 0031800115 scopus 로고    scopus 로고
    • Expression of matrix metalloproteinases (MMP-1 and -2) and their inhibitors (TIMP-1, -2 and -3) in oral lichen planus, dysplasia, squamous cell carcinoma and lymph node metastasis
    • 1:CAS:528:DyaK1cXktlCmtb8%3D 9649139
    • M Sutinen T Kainulainen T Hurskainen E Vesterlund JP Alexander CM Overall, et al. 1998 Expression of matrix metalloproteinases (MMP-1 and -2) and their inhibitors (TIMP-1, -2 and -3) in oral lichen planus, dysplasia, squamous cell carcinoma and lymph node metastasis British Journal of Cancer 77 2239 2245 1:CAS:528:DyaK1cXktlCmtb8%3D 9649139
    • (1998) British Journal of Cancer , vol.77 , pp. 2239-2245
    • Sutinen, M.1    Kainulainen, T.2    Hurskainen, T.3    Vesterlund, E.4    Alexander, J.P.5    Overall, C.M.6
  • 174
    • 0031935056 scopus 로고    scopus 로고
    • 72-kD (MMP-2) and 92-kD (MMP-9) type IV collagenase production and activity in different histologic types of lung cancer cells
    • DOI 10.1159/000027989
    • G Gonzalez-Avila C Iturria F Vadillo L Teran M Selman R Perez-Tamayo 1998 72-kD (MMP-2) and 92-kD (MMP-9) type IV collagenase production and activity in different histologic types of lung cancer cells Pathobiology 66 5 16 1:CAS:528:DyaK1cXit1Wgtr8%3D 9577961 10.1159/000027989 (Pubitemid 28140597)
    • (1998) Pathobiology , vol.66 , Issue.1 , pp. 5-16
    • Gonzalez-Avila, G.1    Iturria, C.2    Vadillo, F.3    Teran, L.4    Selman, M.5    Perez-Tamayo, R.6
  • 175
    • 0030785679 scopus 로고    scopus 로고
    • Expression of matrix metalloproteinases and their inhibitors in human bronchopulmonary carcinomas: Quantificative and morphological analyses
    • B Nawrocki M Polette V Marchand M Monteau P Gillery JM Tournier, et al. 1997 Expression of matrix metalloproteinases and their inhibitors in human bronchopulmonary carcinomas: Quantificative and morphological analyses International Journal of Cancer 72 556 564
    • (1997) International Journal of Cancer , vol.72 , pp. 556-564
    • Nawrocki, B.1    Polette, M.2    Marchand, V.3    Monteau, M.4    Gillery, P.5    Tournier, J.M.6
  • 176
    • 65749308863 scopus 로고    scopus 로고
    • The matrix metalloproteinases and their inhibitors in pancreatic cancer. from molecular science to a clinical application
    • 1:CAS:528:DyaK2sXjtFemsLw%3D 9127168
    • SR Bramhall 1997 The matrix metalloproteinases and their inhibitors in pancreatic cancer. From molecular science to a clinical application International Journal of Pancreatology 21 1 12 1:CAS:528:DyaK2sXjtFemsLw%3D 9127168
    • (1997) International Journal of Pancreatology , vol.21 , pp. 1-12
    • Bramhall, S.R.1
  • 177
    • 0030970119 scopus 로고    scopus 로고
    • Emerging roles for cysteine proteases in human biology
    • DOI 10.1146/annurev.physiol.59.1.63
    • HA Chapman RJ Riese GP Shi 1997 Emerging roles for cysteine proteases in human biology Annual Review of Physiology 59 63 88 1:CAS:528:DyaK2sXhvVSjt7g%3D 9074757 10.1146/annurev.physiol.59.1.63 (Pubitemid 27142435)
    • (1997) Annual Review of Physiology , vol.59 , pp. 63-88
    • Chapman, H.A.1    Riese, R.J.2    Shi, G.-P.3
  • 179
    • 0025879527 scopus 로고
    • Essential AP-1 and PEA3 binding elements in the human urokinase enhancer display cell type-specific activity
    • 1:CAS:528:DyaK3MXmslahsrY%3D 1923525
    • C Nerlov P Rorth F Blasi M Johnsen 1991 Essential AP-1 and PEA3 binding elements in the human urokinase enhancer display cell type-specific activity Oncogene 6 1583 1592 1:CAS:528:DyaK3MXmslahsrY%3D 1923525
    • (1991) Oncogene , vol.6 , pp. 1583-1592
    • Nerlov, C.1    Rorth, P.2    Blasi, F.3    Johnsen, M.4
  • 180
    • 0030010553 scopus 로고    scopus 로고
    • Regulation of urokinase-type plasminogen activator expression by an ERK1-dependent signaling pathway in a squamous cell carcinoma cell line
    • E Lengyel R Gum E Stepp J Juarez H Wang D Boyd 1996 Regulation of urokinase-type plasminogen activator expression by an ERK1-dependent signaling pathway in a squamous cell carcinoma cell line Journal of Cellular Biochemistry 61 430 443
    • (1996) Journal of Cellular Biochemistry , vol.61 , pp. 430-443
    • Lengyel, E.1    Gum, R.2    Stepp, E.3    Juarez, J.4    Wang, H.5    Boyd, D.6
  • 181
    • 0035127868 scopus 로고    scopus 로고
    • The role and regulation of urokinase-type plasminogen activator receptor gene expression in cancer invasion and metastasis
    • Y Wang 2001 The role and regulation of urokinase-type plasminogen activator receptor gene expression in cancer invasion and metastasis Medicinal Research Reviews 21 146 170
    • (2001) Medicinal Research Reviews , vol.21 , pp. 146-170
    • Wang, Y.1
  • 183
    • 33750442231 scopus 로고    scopus 로고
    • A novel anticancer effect of garlic derivatives: Inhibition of cancer cell invasion through restoration of E-cadherin expression
    • DOI 10.1093/carcin/bgl054
    • Q Chu MT Ling H Feng HW Cheung SW Tsao X Wang, et al. 2006 A novel anticancer effect of garlic derivatives: Inhibition of cancer cell invasion through restoration of E-cadherin expression Carcinogenesis 27 2180 2189 1:CAS:528:DC%2BD28XhtFKltr3J 16675472 10.1093/carcin/bgl054 (Pubitemid 44644806)
    • (2006) Carcinogenesis , vol.27 , Issue.11 , pp. 2180-2189
    • Chu, Q.1    Ling, M.-T.2    Feng, H.3    Cheung, H.W.4    Tsao, S.W.5    Wang, X.6    Wong, Y.C.7
  • 184
    • 33645216691 scopus 로고    scopus 로고
    • Allyl isothiocyanate and its N-acetylcysteine conjugate suppress metastasis via inhibition of invasion, migration, and matrix metalloproteinase-2/-9 activities in SK-Hep 1 human hepatoma cells
    • 1:CAS:528:DC%2BD28Xjt1Sjtb4%3D
    • ES Hwang HJ Lee 2006 Allyl isothiocyanate and its N-acetylcysteine conjugate suppress metastasis via inhibition of invasion, migration, and matrix metalloproteinase-2/-9 activities in SK-Hep 1 human hepatoma cells Experimental Biology and Medicine (Maywood, NJ) 231 421 430 1:CAS:528:DC%2BD28Xjt1Sjtb4%3D
    • (2006) Experimental Biology and Medicine (Maywood, NJ) , vol.231 , pp. 421-430
    • Hwang, E.S.1    Lee, H.J.2
  • 185
    • 33845720433 scopus 로고    scopus 로고
    • Role of HER2/HER3 co-receptor in breast carcinogenesis
    • 1:CAS:528:DC%2BD28XnsF0%3D 16556064 10.2217/14796694.1.6.841
    • TD Way JK Lin 2005 Role of HER2/HER3 co-receptor in breast carcinogenesis Future Oncology 1 841 849 1:CAS:528:DC%2BD28XnsF0%3D 16556064 10.2217/14796694.1.6.841
    • (2005) Future Oncology , vol.1 , pp. 841-849
    • Way, T.D.1    Lin, J.K.2
  • 186
    • 33644926465 scopus 로고    scopus 로고
    • Flavonoids inhibit melanoma lung metastasis by impairing tumor cells endothelium interactions
    • 1:CAS:528:DC%2BD28XisFOjsr8%3D 16222712 10.1002/jcp.20510
    • M Piantelli C Rossi M Iezzi R La Sorda S Iacobelli S Alberti, et al. 2006 Flavonoids inhibit melanoma lung metastasis by impairing tumor cells endothelium interactions Journal of Cellular Physiology 207 23 29 1:CAS:528:DC%2BD28XisFOjsr8%3D 16222712 10.1002/jcp.20510
    • (2006) Journal of Cellular Physiology , vol.207 , pp. 23-29
    • Piantelli, M.1    Rossi, C.2    Iezzi, M.3    La Sorda, R.4    Iacobelli, S.5    Alberti, S.6
  • 187
    • 70350459062 scopus 로고    scopus 로고
    • Berberine inhibits metastasis of nasopharyngeal carcinoma 5-8F cells by targeting Rho kinase-mediated Ezrin phosphorylation at threonine 567
    • 1:CAS:528:DC%2BD1MXhtFyjs77E 19651779 10.1074/jbc.M109.033795
    • F Tang D Wang C Duan D Huang Y Wu Y Chen, et al. 2009 Berberine inhibits metastasis of nasopharyngeal carcinoma 5-8F cells by targeting Rho kinase-mediated Ezrin phosphorylation at threonine 567 The Journal of Biological Chemistry 284 27456 27466 1:CAS:528:DC%2BD1MXhtFyjs77E 19651779 10.1074/jbc.M109.033795
    • (2009) The Journal of Biological Chemistry , vol.284 , pp. 27456-27466
    • Tang, F.1    Wang, D.2    Duan, C.3    Huang, D.4    Wu, Y.5    Chen, Y.6
  • 188
    • 44449141072 scopus 로고    scopus 로고
    • A novel anticancer effect of butein: Inhibition of invasion through the ERK1/2 and NF-kappa B signaling pathways in bladder cancer cells
    • 1:CAS:528:DC%2BD1cXms1WitL8%3D 18472007 10.1016/j.febslet.2008.04.046
    • L Zhang W Chen X Li 2008 A novel anticancer effect of butein: Inhibition of invasion through the ERK1/2 and NF-kappa B signaling pathways in bladder cancer cells FEBS Letters 582 1821 1828 1:CAS:528:DC%2BD1cXms1WitL8%3D 18472007 10.1016/j.febslet.2008.04.046
    • (2008) FEBS Letters , vol.582 , pp. 1821-1828
    • Zhang, L.1    Chen, W.2    Li, X.3
  • 189
    • 34547125342 scopus 로고    scopus 로고
    • Butein, a tetrahydroxychalcone, inhibits nuclear factor (NF)-κB and NF-κB-regulated gene expression through direct inhibition of IκBα kinase β on cysteine 179 residue
    • DOI 10.1074/jbc.M700890200
    • MK Pandey SK Sandur B Sung G Sethi AB Kunnumakkara BB Aggarwal 2007 Butein, a tetrahydroxychalcone, inhibits nuclear factor (NF)-kappaB and NF-kappaB-regulated gene expression through direct inhibition of IkappaBalpha kinase beta on cysteine 179 residue The Journal of Biological Chemistry 282 17340 17350 1:CAS:528:DC%2BD2sXmt1eksL4%3D 17439942 10.1074/jbc.M700890200 (Pubitemid 47100316)
    • (2007) Journal of Biological Chemistry , vol.282 , Issue.24 , pp. 17340-17350
    • Pandey, M.K.1    Sandur, S.K.2    Sung, B.3    Sethi, G.4    Kunnumakkara, A.B.5    Aggarwal, B.B.6
  • 190
    • 12344329635 scopus 로고    scopus 로고
    • A new matrix metalloproteinase-9 inhibitor 3,4-dihydroxycinnamic acid (caffeic acid) from methanol extract of Euonymus alatus: Isolation and structure determination
    • DOI 10.1016/j.tox.2004.10.008, PII S0300483X0400589X
    • WH Park SH Kim CH Kim 2005 A new matrix metalloproteinase-9 inhibitor 3,4-dihydroxycinnamic acid (caffeic acid) from methanol extract of Euonymus alatus: Isolation and structure determination Toxicology 207 383 390 1:CAS:528:DC%2BD2MXms1Kqtg%3D%3D 15664266 10.1016/j.tox.2004.10.008 (Pubitemid 40138935)
    • (2005) Toxicology , vol.207 , Issue.3 , pp. 383-390
    • Park, W.-H.1    Kim, S.-H.2    Kim, C.-H.3
  • 191
    • 57349126316 scopus 로고    scopus 로고
    • Inhibitory effect of capsaicin on B16-F10 melanoma cell migration via the phosphatidylinositol 3-kinase/Akt/Rac1 signal pathway
    • DOI 10.3858/emm.2008.40.5.486
    • DH Shin OH Kim HS Jun MK Kang 2008 Inhibitory effect of capsaicin on B16-F10 melanoma cell migration via the phosphatidylinositol 3-kinase/Akt/Rac1 signal pathway Experimental & Molecular Medicine 40 486 494 1:CAS:528:DC%2BD1cXhtlOgtb7P 10.3858/emm.2008.40.5.486 (Pubitemid 352789088)
    • (2008) Experimental and Molecular Medicine , vol.40 , Issue.5 , pp. 486-494
    • Shin, D.-H.1    Kim, O.-H.2    Jun, H.-S.3    Kang, M.-K.4
  • 192
    • 13844272556 scopus 로고    scopus 로고
    • Carnosol inhibits the invasion of B16/F10 mouse melanoma cells by suppressing metalloproteinase-9 through down-regulating nuclear factor-kappaB and c-Jun
    • DOI 10.1016/j.bcp.2004.09.019
    • SC Huang CT Ho SY Lin-Shiau JK Lin 2005 Carnosol inhibits the invasion of B16/F10 mouse melanoma cells by suppressing metalloproteinase-9 through down-regulating nuclear factor-kappa B and c-Jun Biochemical Pharmacology 69 221 232 1:CAS:528:DC%2BD2cXhtFGhtbfM 15627474 10.1016/j.bcp.2004.09.019 (Pubitemid 41556568)
    • (2005) Biochemical Pharmacology , vol.69 , Issue.2 , pp. 221-232
    • Huang, S.-C.1    Ho, C.-T.2    Lin-Shiau, S.-Y.3    Lin, J.-K.4
  • 193
    • 0034599893 scopus 로고    scopus 로고
    • Inhibitory effects of carotenoids on the invasion of rat ascites hepatoma cells in culture
    • DOI 10.1016/S0304-3835(99)00418-8, PII S0304383599004188
    • Y Kozuki Y Miura K Yagasaki 2000 Inhibitory effects of carotenoids on the invasion of rat ascites hepatoma cells in culture Cancer Letters 151 111 115 1:CAS:528:DC%2BD3cXitFKrtLo%3D 10766430 10.1016/S0304-3835(99)00418-8 (Pubitemid 30155592)
    • (2000) Cancer Letters , vol.151 , Issue.1 , pp. 111-115
    • Kozuki, Y.1    Miura, Y.2    Yagasaki, K.3
  • 194
    • 34247854884 scopus 로고    scopus 로고
    • Phenolic phytochemicals derived from red pine (Pinus densiflora) inhibit the invasion and migration of SK-Hep-1 human hepatocellular carcinoma cells
    • DOI 10.1196/annals.1397.058, Signal Transduction Pathways, Part C: Cell Signaling in Health and Disease
    • SJ Lee KW Lee HJ Hur JY Chun SY Kim HJ Lee 2007 Phenolic phytochemicals derived from red pine (Pinus densiflora) inhibit the invasion and migration of SK-Hep-1 human hepatocellular carcinoma cells Annals of the New York Academy of Sciences 1095 536 544 1:CAS:528:DC%2BD2sXks1Grsr8%3D 17404067 10.1196/annals.1397.058 (Pubitemid 47092485)
    • (2007) Annals of the New York Academy of Sciences , vol.1095 , pp. 536-544
    • Sang, J.L.1    Ki, W.L.2    Haeng, J.H.3    Ji, Y.C.4    Seo, Y.K.5    Hyong, J.L.6
  • 195
    • 77954917015 scopus 로고    scopus 로고
    • Celastrol acts as a potent anti-metastatic agent targeting {beta}1 integrin and inhibiting cell-ECM adhesion, partially via the p38 MAPK pathway
    • 20472666 10.1124/jpet.110.165654
    • H Zhu XW Liu TY Cai J Cao CX Tu W Lu, et al. 2010 Celastrol acts as a potent anti-metastatic agent targeting {beta}1 integrin and inhibiting cell-ECM adhesion, partially via the p38 MAPK pathway Journal of Pharmacology and Experimental Therapeutics 334 489 499 20472666 10.1124/jpet.110.165654
    • (2010) Journal of Pharmacology and Experimental Therapeutics , vol.334 , pp. 489-499
    • Zhu, H.1    Liu, X.W.2    Cai, T.Y.3    Cao, J.4    Tu, C.X.5    Lu, W.6
  • 196
    • 33745843700 scopus 로고    scopus 로고
    • Crocetin inhibits leukocyte adherence to vascular endothelial cells induced by AGEs
    • DOI 10.1016/j.jep.2006.01.022, PII S0378874106000754
    • M Xiang ZY Qian CH Zhou J Liu WN Li 2006 Crocetin inhibits leukocyte adherence to vascular endothelial cells induced by AGEs Journal of Ethnopharmacology 107 25 31 1:CAS:528:DC%2BD28XntFWqsrY%3D 16529888 10.1016/j.jep.2006.01.022 (Pubitemid 44038808)
    • (2006) Journal of Ethnopharmacology , vol.107 , Issue.1 , pp. 25-31
    • Xiang, M.1    Qian, Z.-Y.2    Zhou, C.-H.3    Liu, J.4    Li, W.-N.5
  • 197
    • 77349086587 scopus 로고    scopus 로고
    • Curcumin blocks migration and invasion of mouse-rat hybrid retina ganglion cells (N18) through the inhibition of MMP-2, -9, FAK, Rho A and Rock-1 gene expression
    • 1:CAS:528:DC%2BC3cXjtlGrsbg%3D 20127004 10.3892/or00000679
    • HJ Lin CC Su HF Lu JS Yang SC Hsu SW Ip, et al. 2010 Curcumin blocks migration and invasion of mouse-rat hybrid retina ganglion cells (N18) through the inhibition of MMP-2, -9, FAK, Rho A and Rock-1 gene expression Oncology Reports 23 665 670 1:CAS:528:DC%2BC3cXjtlGrsbg%3D 20127004 10.3892/or00000679
    • (2010) Oncology Reports , vol.23 , pp. 665-670
    • Lin, H.J.1    Su, C.C.2    Lu, H.F.3    Yang, J.S.4    Hsu, S.C.5    Ip, S.W.6
  • 199
    • 33846581064 scopus 로고    scopus 로고
    • Antiangiogenic activity of Diallyl Sulfide (DAS)
    • DOI 10.1016/j.intimp.2006.10.011, PII S1567576906003195
    • P Thejass G Kuttan 2007 Antiangiogenic activity of diallyl sulfide (DAS) International Immunopharmacology 7 295 305 1:CAS:528:DC%2BD2sXhtlSltrw%3D 17276887 10.1016/j.intimp.2006.10.011 (Pubitemid 46186169)
    • (2007) International Immunopharmacology , vol.7 , Issue.3 , pp. 295-305
    • Thejass, P.1    Kuttan, G.2
  • 200
    • 43449106769 scopus 로고    scopus 로고
    • CXCR4 and CXCL12 down-regulation: A novel mechanism for the chemoprotection of 3,3′-diindolylmethane for breast and ovarian cancers
    • 1:CAS:528:DC%2BD1cXlvFyhs7c%3D 18378071 10.1016/j.canlet.2008.02.033
    • EL Hsu N Chen A Westbrook F Wang R Zhang RT Taylor, et al. 2008 CXCR4 and CXCL12 down-regulation: A novel mechanism for the chemoprotection of 3,3′-diindolylmethane for breast and ovarian cancers Cancer Letters 265 113 123 1:CAS:528:DC%2BD1cXlvFyhs7c%3D 18378071 10.1016/j.canlet.2008.02.033
    • (2008) Cancer Letters , vol.265 , pp. 113-123
    • Hsu, E.L.1    Chen, N.2    Westbrook, A.3    Wang, F.4    Zhang, R.5    Taylor, R.T.6
  • 202
    • 1642410959 scopus 로고    scopus 로고
    • Treatment of Epigallocatechin-3-Gallate Inhibits Matrix Metalloproteinases-2 and -9 via Inhibition of Activation of Mitogen-Activated Protein Kinases, c-jun and NF-κB in Human Prostate Carcinoma DU-145 Cells
    • DOI 10.1002/pros.10352
    • PK Vayalil SK Katiyar 2004 Treatment of epigallocatechin-3-gallate inhibits matrix metalloproteinases-2 and -9 via inhibition of activation of mitogen-activated protein kinases, c-jun and NF-kappaB in human prostate carcinoma DU-145 cells The Prostate 59 33 42 1:CAS:528:DC%2BD2cXjsVWlt7g%3D 14991864 10.1002/pros.10352 (Pubitemid 38387841)
    • (2004) Prostate , vol.59 , Issue.1 , pp. 33-42
    • Vayalil, P.K.1    Katiyar, S.K.2
  • 203
    • 15844425433 scopus 로고    scopus 로고
    • Repressions of MMP-9 expression and NF-κB localization are involved in inhibition of lung carcinoma 95-D cell invasion by (-)-epigallocatechin-3- gallate
    • DOI 10.1016/j.biopha.2005.01.004
    • J Yang D Wei J Liu 2005 Repressions of MMP-9 expression and NF-kappa B localization are involved in inhibition of lung carcinoma 95-D cell invasion by (-)-epigallocatechin-3-gallate Biomedicine & Pharmacotherapy 59 98 103 1:CAS:528:DC%2BD2MXivVSnsb4%3D 10.1016/j.biopha.2005.01.004 (Pubitemid 40424556)
    • (2005) Biomedicine and Pharmacotherapy , vol.59 , Issue.3 , pp. 98-103
    • Yang, J.1    Wei, D.2    Liu, J.3
  • 204
    • 70349923402 scopus 로고    scopus 로고
    • Involvement of the ERK signaling pathway in fisetin reduces invasion and migration in the human lung cancer cell line A549
    • 1:CAS:528:DC%2BD1MXhtVOnsrjO 19725538 10.1021/jf902630w
    • YC Liao YW Shih CH Chao XY Lee TA Chiang 2009 Involvement of the ERK signaling pathway in fisetin reduces invasion and migration in the human lung cancer cell line A549 Journal of Agricultural and Food Chemistry 57 8933 8941 1:CAS:528:DC%2BD1MXhtVOnsrjO 19725538 10.1021/jf902630w
    • (2009) Journal of Agricultural and Food Chemistry , vol.57 , pp. 8933-8941
    • Liao, Y.C.1    Shih, Y.W.2    Chao, C.H.3    Lee, X.Y.4    Chiang, T.A.5
  • 205
    • 0030968290 scopus 로고    scopus 로고
    • Overexpression of the c-erbB-2 gene enhanced intrinsic metastasis potential in human breast cancer cells without increasing their transformation abilities
    • 1:CAS:528:DyaK2sXhvFOitr8%3D 9067293
    • M Tan J Yao D Yu 1997 Overexpression of the c-erbB-2 gene enhanced intrinsic metastasis potential in human breast cancer cells without increasing their transformation abilities Cancer Research 57 1199 1205 1:CAS:528: DyaK2sXhvFOitr8%3D 9067293
    • (1997) Cancer Research , vol.57 , pp. 1199-1205
    • Tan, M.1    Yao, J.2    Yu, D.3
  • 206
    • 0033960068 scopus 로고    scopus 로고
    • Induction of apoptosis and inhibition of c-erbB-2 in breast cancer cells by flavopiridol
    • 1:CAS:528:DC%2BD3cXhtVCjsrc%3D 10656453
    • Y Li M Bhuiyan S Alhasan AM Senderowicz FH Sarkar 2000 Induction of apoptosis and inhibition of c-erbB-2 in breast cancer cells by flavopiridol Clinical Cancer Research 6 223 229 1:CAS:528:DC%2BD3cXhtVCjsrc%3D 10656453
    • (2000) Clinical Cancer Research , vol.6 , pp. 223-229
    • Li, Y.1    Bhuiyan, M.2    Alhasan, S.3    Senderowicz, A.M.4    Sarkar, F.H.5
  • 207
    • 46449138184 scopus 로고    scopus 로고
    • Ganoderic acids suppress growth and invasive behavior of breast cancer cells by modulating AP-1 and NF-kappaB signaling
    • 1:CAS:528:DC%2BD1cXmt1amtL4%3D 18425349
    • J Jiang B Grieb A Thyagarajan D Sliva 2008 Ganoderic acids suppress growth and invasive behavior of breast cancer cells by modulating AP-1 and NF-kappaB signaling International Journal of Molecular Medicine 21 577 584 1:CAS:528:DC%2BD1cXmt1amtL4%3D 18425349
    • (2008) International Journal of Molecular Medicine , vol.21 , pp. 577-584
    • Jiang, J.1    Grieb, B.2    Thyagarajan, A.3    Sliva, D.4
  • 208
    • 16644367866 scopus 로고    scopus 로고
    • Soy isoflavones suppress invasiveness of breast cancer cells by the inhibition of NF-kappaB/AP-1-dependent and -independent pathways
    • 1:CAS:528:DC%2BD2cXhtVSktbnI 15492830
    • T Valachovicova V Slivova H Bergman J Shuherk D Sliva 2004 Soy isoflavones suppress invasiveness of breast cancer cells by the inhibition of NF-kappaB/AP-1-dependent and -independent pathways International Journal of Oncology 25 1389 1395 1:CAS:528:DC%2BD2cXhtVSktbnI 15492830
    • (2004) International Journal of Oncology , vol.25 , pp. 1389-1395
    • Valachovicova, T.1    Slivova, V.2    Bergman, H.3    Shuherk, J.4    Sliva, D.5
  • 209
    • 41849124923 scopus 로고    scopus 로고
    • [6]-Gingerol inhibits metastasis of MDA-MB-231 human breast cancer cells
    • DOI 10.1016/j.jnutbio.2007.05.008, PII S0955286307001337
    • HS Lee EY Seo NE Kang WK Kim 2008 [6]-Gingerol inhibits metastasis of MDA-MB-231 human breast cancer cells The Journal of Nutritional Biochemistry 19 313 319 1:CAS:528:DC%2BD1cXks1Gjtbw%3D 17683926 10.1016/j.jnutbio.2007.05.008 (Pubitemid 351503763)
    • (2008) Journal of Nutritional Biochemistry , vol.19 , Issue.5 , pp. 313-319
    • Lee, H.S.1    Seo, E.Y.2    Kang, N.E.3    Kim, W.K.4
  • 210
    • 0034042381 scopus 로고    scopus 로고
    • Suppression of breast cancer invasion and migration by indole-3-carbinol: Associated with up-regulation of BRCA1 and E-cadherin/catenin complexes
    • 1:CAS:528:DC%2BD3cXlsF2gsLo%3D 10868478 10.1007/s001090000088
    • Q Meng M Qi DZ Chen R Yuan ID Goldberg EM Rosen, et al. 2000 Suppression of breast cancer invasion and migration by indole-3-carbinol: Associated with up-regulation of BRCA1 and E-cadherin/catenin complexes Journal of Molecular Medicine 78 155 165 1:CAS:528:DC%2BD3cXlsF2gsLo%3D 10868478 10.1007/ s001090000088
    • (2000) Journal of Molecular Medicine , vol.78 , pp. 155-165
    • Meng, Q.1    Qi, M.2    Chen, D.Z.3    Yuan, R.4    Goldberg, I.D.5    Rosen, E.M.6
  • 211
    • 24744436403 scopus 로고    scopus 로고
    • Lycopene inhibits cell migration and invasion and upregulates Nm23-H1 in a highly invasive hepatocarcinoma, SK-Hep-1 cells
    • 1:CAS:528:DC%2BD2MXhtVSktbbP 16140886
    • CS Huang MK Shih CH Chuang ML Hu 2005 Lycopene inhibits cell migration and invasion and upregulates Nm23-H1 in a highly invasive hepatocarcinoma, SK-Hep-1 cells The Journal of Nutrition 135 2119 2123 1:CAS:528: DC%2BD2MXhtVSktbbP 16140886
    • (2005) The Journal of Nutrition , vol.135 , pp. 2119-2123
    • Huang, C.S.1    Shih, M.K.2    Chuang, C.H.3    Hu, M.L.4
  • 212
    • 14844321265 scopus 로고    scopus 로고
    • Myricetin inhibits matrix metalloproteinase 2 protein expression and enzyme activity in colorectal carcinoma cells
    • 1:CAS:528:DC%2BD2MXhtlersr8%3D 15713899
    • CH Ko SC Shen TJ Lee YC Chen 2005 Myricetin inhibits matrix metalloproteinase 2 protein expression and enzyme activity in colorectal carcinoma cells Molecular Cancer Therapeutics 4 281 290 1:CAS:528: DC%2BD2MXhtlersr8%3D 15713899
    • (2005) Molecular Cancer Therapeutics , vol.4 , pp. 281-290
    • Ko, C.H.1    Shen, S.C.2    Lee, T.J.3    Chen, Y.C.4
  • 213
    • 8644238077 scopus 로고    scopus 로고
    • Piperine is a potent inhibitor of nuclear factor-κB (NF-κB), c-Fos, CREB, ATF-2 and proinflammatory cytokine gene expression in B16F-10 melanoma cells
    • DOI 10.1016/j.intimp.2004.08.005, PII S1567576904002723
    • CR Pradeep G Kuttan 2004 Piperine is a potent inhibitor of nuclear factor-kappaB (NF-kappaB), c-Fos, CREB, ATF-2 and proinflammatory cytokine gene expression in B16F-10 melanoma cells International Immunopharmacology 4 1795 1803 1:CAS:528:DC%2BD2cXptl2lurk%3D 15531295 10.1016/j.intimp.2004.08.005 (Pubitemid 39504820)
    • (2004) International Immunopharmacology , vol.4 , Issue.14 SPEC. ISSUE , pp. 1795-1803
    • Pradeep, C.R.1    Kuttan, G.2
  • 214
    • 33745945847 scopus 로고    scopus 로고
    • Quercetin downregulates matrix metalloproteinases 2 and 9 proteins expression in prostate cancer cells (PC-3)
    • DOI 10.1007/s11010-005-9085-3
    • MR Vijayababu A Arunkumar P Kanagaraj P Venkataraman G Krishnamoorthy J Arunakaran 2006 Quercetin downregulates matrix metalloproteinases 2 and 9 proteins expression in prostate cancer cells (PC-3) Molecular and Cellular Biochemistry 287 109 116 1:CAS:528:DC%2BD28XmvVaqs70%3D 16645725 10.1007/s11010-005-9085-3 (Pubitemid 44057398)
    • (2006) Molecular and Cellular Biochemistry , vol.287 , Issue.1-2 , pp. 109-116
    • Vijayababu, M.R.1    Arunkumar, A.2    Kanagaraj, P.3    Venkataraman, P.4    Krishnamoorthy, G.5    Arunakaran, J.6
  • 215
    • 77957590701 scopus 로고    scopus 로고
    • Resveratrol inhibits human lung adenocarcinoma cell metastasis by suppressing heme oxygenase 1-mediated nuclear factor-kappaB pathway and subsequently downregulating expression of matrix metalloproteinases
    • 1:CAS:528:DC%2BC3cXptl2ju7w%3D 20461740 10.1002/mnfr.200900550
    • PL Liu JR Tsai AL Charles JJ Hwang SH Chou YH Ping, et al. 2010 Resveratrol inhibits human lung adenocarcinoma cell metastasis by suppressing heme oxygenase 1-mediated nuclear factor-kappaB pathway and subsequently downregulating expression of matrix metalloproteinases Molecular Nutrition and Food Research 54 S196 S204 1:CAS:528:DC%2BC3cXptl2ju7w%3D 20461740 10.1002/mnfr.200900550
    • (2010) Molecular Nutrition and Food Research , vol.54
    • Liu, P.L.1    Tsai, J.R.2    Charles, A.L.3    Hwang, J.J.4    Chou, S.H.5    Ping, Y.H.6
  • 216
    • 33744824356 scopus 로고    scopus 로고
    • Silibinin inhibits invasion of oral cancer cells by suppressing the MAPK pathway
    • DOI 10.1177/154405910608500303
    • PN Chen YS Hsieh CL Chiang HL Chiou SF Yang SC Chu 2006 Silibinin inhibits invasion of oral cancer cells by suppressing the MAPK pathway Journal of Dental Research 85 220 225 1:CAS:528:DC%2BD28Xis1OqsL8%3D 16498067 10.1177/154405910608500303 (Pubitemid 43827728)
    • (2006) Journal of Dental Research , vol.85 , Issue.3 , pp. 220-225
    • Chen, P.-N.1    Hsieh, Y.-S.2    Chiang, C.-L.3    Chiou, H.-L.4    Yang, S.-F.5    Chu, S.-C.6
  • 217
    • 3142765979 scopus 로고    scopus 로고
    • Silibinin inhibits the invasion of human lung cancer cells via decreased productions of urokinase-plasminogen activator and matrix metalloproteinase-2
    • DOI 10.1002/mc.20018
    • SC Chu HL Chiou PN Chen SF Yang YS Hsieh 2004 Silibinin inhibits the invasion of human lung cancer cells via decreased productions of urokinase-plasminogen activator and matrix metalloproteinase-2 Molecular Carcinogenesis 40 143 149 1:CAS:528:DC%2BD2cXlvFKgsLs%3D 15224346 10.1002/mc.20018 (Pubitemid 38924841)
    • (2004) Molecular Carcinogenesis , vol.40 , Issue.3 , pp. 143-149
    • Chu, S.-C.1    Chiou, H.-L.2    Chen, P.-H.3    Yang, S.-F.4    Hsieh, Y.-S.5
  • 218
    • 33846326821 scopus 로고    scopus 로고
    • Silibinin suppresses PMA-induced MMP-9 expression by blocking the AP-1 activation via MAPK signaling pathways in MCF-7 human breast carcinoma cells
    • DOI 10.1016/j.bbrc.2006.12.181, PII S0006291X06028476
    • SO Lee YJ Jeong HG Im CH Kim YC Chang IS Lee 2007 Silibinin suppresses PMA-induced MMP-9 expression by blocking the AP-1 activation via MAPK signaling pathways in MCF-7 human breast carcinoma cells Biochemical and Biophysical Research Communications 354 165 171 1:CAS:528:DC%2BD2sXhtVClsrg%3D 17214970 10.1016/j.bbrc.2006.12.181 (Pubitemid 46123215)
    • (2007) Biochemical and Biophysical Research Communications , vol.354 , Issue.1 , pp. 165-171
    • Lee, S.-O.1    Jeong, Y.-J.2    Im, H.G.3    Kim, C.-H.4    Chang, Y.-C.5    Lee, I.-S.6
  • 219
    • 33646201718 scopus 로고    scopus 로고
    • Antimetastatic activity of sulforaphane
    • 1:CAS:528:DC%2BD28XksVagsb4%3D 16600309 10.1016/j.lfs.2005.12.038
    • P Thejass G Kuttan 2006 Antimetastatic activity of sulforaphane Life Sciences 78 3043 3050 1:CAS:528:DC%2BD28XksVagsb4%3D 16600309 10.1016/j.lfs.2005.12.038
    • (2006) Life Sciences , vol.78 , pp. 3043-3050
    • Thejass, P.1    Kuttan, G.2
  • 220
    • 77049086006 scopus 로고    scopus 로고
    • Inhibitory effects of gamma-tocotrienol on invasion and metastasis of human gastric adenocarcinoma SGC-7901 cells
    • 1:CAS:528:DC%2BC3cXitlSks74%3D 19195866 10.1016/j.jnutbio.2008.11.004
    • HK Liu Q Wang Y Li WG Sun JR Liu YM Yang, et al. 2010 Inhibitory effects of gamma-tocotrienol on invasion and metastasis of human gastric adenocarcinoma SGC-7901 cells The Journal of Nutritional Biochemistry 21 206 213 1:CAS:528:DC%2BC3cXitlSks74%3D 19195866 10.1016/j.jnutbio.2008.11.004
    • (2010) The Journal of Nutritional Biochemistry , vol.21 , pp. 206-213
    • Liu, H.K.1    Wang, Q.2    Li, Y.3    Sun, W.G.4    Liu, J.R.5    Yang, Y.M.6
  • 221
    • 65749102893 scopus 로고    scopus 로고
    • Ursolic acid inhibits IL-1beta or TNF-alpha-induced C6 glioma invasion through suppressing the association ZIP/p62 with PKC-zeta and downregulating the MMP-9 expression
    • 1:CAS:528:DC%2BD1MXmvFChtL0%3D 18973186 10.1002/mc.20490
    • HC Huang CY Huang SY Lin-Shiau JK Lin 2009 Ursolic acid inhibits IL-1beta or TNF-alpha-induced C6 glioma invasion through suppressing the association ZIP/p62 with PKC-zeta and downregulating the MMP-9 expression Molecular Carcinogenesis 48 517 531 1:CAS:528:DC%2BD1MXmvFChtL0%3D 18973186 10.1002/mc.20490
    • (2009) Molecular Carcinogenesis , vol.48 , pp. 517-531
    • Huang, H.C.1    Huang, C.Y.2    Lin-Shiau, S.Y.3    Lin, J.K.4
  • 222
    • 55349099143 scopus 로고    scopus 로고
    • Zerumbone down-regulates chemokine receptor CXCR4 expression leading to inhibition of CXCL12-induced invasion of breast and pancreatic tumor cells
    • 1:CAS:528:DC%2BD1cXhtlSkurzN 18974138 10.1158/0008-5472.CAN-08-2155
    • B Sung S Jhurani KS Ahn Y Mastuo T Yi S Guha, et al. 2008 Zerumbone down-regulates chemokine receptor CXCR4 expression leading to inhibition of CXCL12-induced invasion of breast and pancreatic tumor cells Cancer Research 68 8938 8944 1:CAS:528:DC%2BD1cXhtlSkurzN 18974138 10.1158/0008-5472.CAN-08-2155
    • (2008) Cancer Research , vol.68 , pp. 8938-8944
    • Sung, B.1    Jhurani, S.2    Ahn, K.S.3    Mastuo, Y.4    Yi, T.5    Guha, S.6
  • 223
    • 27144512700 scopus 로고    scopus 로고
    • Zerumbone abolishes NF-κB and IκBα kinase activation leading to suppression of antiapoptotic and metastatic gene expression, upregulation of apoptosis, and downregulation of invasion
    • DOI 10.1038/sj.onc.1208845, PII 1208845
    • Y Takada A Murakami BB Aggarwal 2005 Zerumbone abolishes NF-kappaB and IkappaBalpha kinase activation leading to suppression of antiapoptotic and metastatic gene expression, upregulation of apoptosis, and downregulation of invasion Oncogene 24 6957 6969 1:CAS:528:DC%2BD2MXhtFamsLfO 16007145 10.1038/sj.onc.1208845 (Pubitemid 41509418)
    • (2005) Oncogene , vol.24 , Issue.46 , pp. 6957-6969
    • Takada, Y.1    Murakami, A.2    Aggarwal, B.B.3
  • 224
    • 33947732977 scopus 로고    scopus 로고
    • Angiogenesis: An organizing principle for drug discovery?
    • DOI 10.1038/nrd2115, PII NRD2115
    • J Folkman 2007 Angiogenesis: An organizing principle for drug discovery? Nature Reviews. Drug Discovery 6 273 286 1:CAS:528:DC%2BD2sXjs1SisL4%3D 17396134 10.1038/nrd2115 (Pubitemid 46505878)
    • (2007) Nature Reviews Drug Discovery , vol.6 , Issue.4 , pp. 273-286
    • Folkman, J.1
  • 225
    • 33744902836 scopus 로고    scopus 로고
    • Angiogenesis: from plants to blood vessels
    • DOI 10.1016/j.tips.2006.04.006, PII S016561470600109X
    • TP Fan JC Yeh KW Leung PY Yue RN Wong 2006 Angiogenesis: From plants to blood vessels Trends in Pharmacological Sciences 27 297 309 1:CAS:528: DC%2BD28XlsFKktLc%3D 16697473 10.1016/j.tips.2006.04.006 (Pubitemid 43850005)
    • (2006) Trends in Pharmacological Sciences , vol.27 , Issue.6 , pp. 297-309
    • Fan, T.-P.1    Yeh, J.-C.2    Leung, K.W.3    Yue, P.Y.K.4    Wong, R.N.S.5
  • 226
    • 77949906193 scopus 로고    scopus 로고
    • Tumor angiogenesis and novel antiangiogenic strategies
    • 1:CAS:528:DC%2BC3cXisVahsLc%3D
    • MS Gordon DS Mendelson G Kato 2010 Tumor angiogenesis and novel antiangiogenic strategies International Journal of Cancer 126 1777 1787 1:CAS:528:DC%2BC3cXisVahsLc%3D
    • (2010) International Journal of Cancer , vol.126 , pp. 1777-1787
    • Gordon, M.S.1    Mendelson, D.S.2    Kato, G.3
  • 227
    • 0015221083 scopus 로고
    • Tumor angiogenesis: Therapeutic implications
    • 1:STN:280:DyaE38%2FgvVCqsQ%3D%3D 4938153 10.1056/NEJM197108122850711
    • J Folkman 1971 Tumor angiogenesis: Therapeutic implications The New England Journal of Medicine 285 1182 1186 1:STN:280:DyaE38%2FgvVCqsQ%3D%3D 4938153 10.1056/NEJM197108122850711
    • (1971) The New England Journal of Medicine , vol.285 , pp. 1182-1186
    • Folkman, J.1
  • 228
    • 30344443934 scopus 로고    scopus 로고
    • Anti-angiogenesis efficacy of the garlic ingredient alliin and antioxidants: Role of nitric oxide and p53
    • 1:CAS:528:DC%2BD28XptF2rsw%3D%3D 16351512 10.1207/s15327914nc530112
    • AS Mousa SA Mousa 2005 Anti-angiogenesis efficacy of the garlic ingredient alliin and antioxidants: Role of nitric oxide and p53 Nutrition and Cancer 53 104 110 1:CAS:528:DC%2BD28XptF2rsw%3D%3D 16351512 10.1207/ s15327914nc530112
    • (2005) Nutrition and Cancer , vol.53 , pp. 104-110
    • Mousa, A.S.1    Mousa, S.A.2
  • 229
    • 33846417309 scopus 로고    scopus 로고
    • Allyl isothiocyanate (AITC) and phenyl isothiocyanate (PITC) inhibit tumour-specific angiogenesis by downregulating nitric oxide (NO) and tumour necrosis factor-α (TNF-α) production
    • DOI 10.1016/j.niox.2006.09.006, PII S1089860306004083
    • P Thejass G Kuttan 2007 Allyl isothiocyanate (AITC) and phenyl isothiocyanate (PITC) inhibit tumour-specific angiogenesis by downregulating nitric oxide (NO) and tumour necrosis factor-alpha (TNF-alpha) production Nitric Oxide 16 247 257 1:CAS:528:DC%2BD2sXhtVaqtbw%3D 17097904 10.1016/j.niox.2006. 09.006 (Pubitemid 46149387)
    • (2007) Nitric Oxide - Biology and Chemistry , vol.16 , Issue.2 , pp. 247-257
    • Thejass, P.1    Kuttan, G.2
  • 230
    • 61849091494 scopus 로고    scopus 로고
    • Antiangiogenic and proapoptotic activities of allyl isothiocyanate inhibit ascites tumor growth in vivo
    • 1:CAS:528:DC%2BD1MXjvVynsLw%3D 19223371 10.1177/1534735408330716
    • A Kumar SS D'Souza S Tickoo BP Salimath HB Singh 2009 Antiangiogenic and proapoptotic activities of allyl isothiocyanate inhibit ascites tumor growth in vivo Integrative Cancer Therapies 8 75 87 1:CAS:528:DC%2BD1MXjvVynsLw%3D 19223371 10.1177/1534735408330716
    • (2009) Integrative Cancer Therapies , vol.8 , pp. 75-87
    • Kumar, A.1    D'Souza, S.S.2    Tickoo, S.3    Salimath, B.P.4    Singh, H.B.5
  • 231
    • 34047132303 scopus 로고    scopus 로고
    • Apigenin inhibits tumor angiogenesis through decreasing HIF-1α and VEGF expression
    • DOI 10.1093/carcin/bgl205
    • J Fang Q Zhou LZ Liu C Xia X Hu X Shi, et al. 2007 Apigenin inhibits tumor angiogenesis through decreasing HIF-1alpha and VEGF expression Carcinogenesis 28 858 864 1:CAS:528:DC%2BD2sXjslOnsbk%3D 17071632 10.1093/carcin/bgl205 (Pubitemid 46523341)
    • (2007) Carcinogenesis , vol.28 , Issue.4 , pp. 858-864
    • Fang, J.1    Zhou, Q.2    Liu, L.-Z.3    Xia, C.4    Hu, X.5    Shi, X.6    Jiang, B.-H.7
  • 232
    • 34548059697 scopus 로고    scopus 로고
    • Caffeic acid and its synthetic derivative CADPE suppress tumor angiogenesis by blocking STAT3-mediated VEGF expression in human renal carcinoma cells
    • DOI 10.1093/carcin/bgm130
    • JE Jung HS Kim CS Lee DH Park YN Kim MJ Lee, et al. 2007 Caffeic acid and its synthetic derivative CADPE suppress tumor angiogenesis by blocking STAT3-mediated VEGF expression in human renal carcinoma cells Carcinogenesis 28 1780 1787 1:CAS:528:DC%2BD2sXpt1ehtbc%3D 17557905 10.1093/carcin/bgm130 (Pubitemid 47289042)
    • (2007) Carcinogenesis , vol.28 , Issue.8 , pp. 1780-1787
    • Jung, J.E.1    Kim, H.S.2    Lee, C.-S.3    Park, D.-H.4    Kim, Y.-N.5    Lee, M.-J.6    Lee, J.W.7    Park, J.-W.8    Kim, M.-S.9    Ye, S.K.10    Chung, M.-H.11
  • 234
    • 0036884617 scopus 로고    scopus 로고
    • Angiogenesis induced by advanced glycation end products and its prevention by cerivastatin
    • 1:CAS:528:DC%2BD38Xps1Kqur8%3D 12368225
    • T Okamoto S Yamagishi Y Inagaki S Amano K Koga R Abe, et al. 2002 Angiogenesis induced by advanced glycation end products and its prevention by cerivastatin The FASEB Journal 16 1928 1930 1:CAS:528:DC%2BD38Xps1Kqur8%3D 12368225
    • (2002) The FASEB Journal , vol.16 , pp. 1928-1930
    • Okamoto, T.1    Yamagishi, S.2    Inagaki, Y.3    Amano, S.4    Koga, K.5    Abe, R.6
  • 235
    • 0242694978 scopus 로고    scopus 로고
    • Enzyme induction and dietary chemicals as approaches to cancer chemoprevention: The Seventh DeWitt S. Goodman Lecture
    • 1:CAS:528:DC%2BD3sXovVGls7g%3D 14612489
    • AH Conney 2003 Enzyme induction and dietary chemicals as approaches to cancer chemoprevention: The Seventh DeWitt S. Goodman Lecture Cancer research 63 7005 7031 1:CAS:528:DC%2BD3sXovVGls7g%3D 14612489
    • (2003) Cancer Research , vol.63 , pp. 7005-7031
    • Conney, A.H.1
  • 236
    • 9244232732 scopus 로고    scopus 로고
    • CDNA microarray analysis of endothelial cells in response to green tea reveals a suppressive phenotype
    • 1:CAS:528:DC%2BD2cXlslylsro%3D 15202006
    • MR Sartippour D Heber S Henning D Elashoff R Elashoff R Rubio, et al. 2004 cDNA microarray analysis of endothelial cells in response to green tea reveals a suppressive phenotype International Journal of Oncology 25 193 202 1:CAS:528:DC%2BD2cXlslylsro%3D 15202006
    • (2004) International Journal of Oncology , vol.25 , pp. 193-202
    • Sartippour, M.R.1    Heber, D.2    Henning, S.3    Elashoff, D.4    Elashoff, R.5    Rubio, R.6
  • 238
    • 0042158654 scopus 로고    scopus 로고
    • Comparative effects of polyphenols from green tea (EGCG) and soybean (genistein) on VEGF and IL-8 release from normal human keratinocytes stimulated with the proinflammatory cytokine TNFα
    • DOI 10.1007/s00403-003-0402-y
    • S Trompezinski A Denis D Schmitt J Viac 2003 Comparative effects of polyphenols from green tea (EGCG) and soybean (genistein) on VEGF and IL-8 release from normal human keratinocytes stimulated with the proinflammatory cytokine TNFalpha Archives for Dermatological Research 295 112 116 1:CAS:528:DC%2BD3sXls1ygu70%3D 10.1007/s00403-003-0402-y (Pubitemid 36960540)
    • (2003) Archives of Dermatological Research , vol.295 , Issue.3 , pp. 112-116
    • Trompezinski, S.1    Denis, A.2    Schmitt, D.3    Viac, J.4
  • 239
    • 0035937335 scopus 로고    scopus 로고
    • EGCG, a major component of green tea, inhibits tumour growth by inhibiting VEGF induction in human colon carcinoma cells
    • DOI 10.1054/bjoc.2000.1691
    • YD Jung MS Kim BA Shin KO Chay BW Ahn W Liu, et al. 2001 EGCG, a major component of green tea, inhibits tumour growth by inhibiting VEGF induction in human colon carcinoma cells British Journal of Cancer 84 844 850 1:CAS:528:DC%2BD3MXivVGrt7Y%3D 11259102 10.1054/bjoc.2000.1691 (Pubitemid 32275661)
    • (2001) British Journal of Cancer , vol.84 , Issue.6 , pp. 844-850
    • Jung, Y.D.1    Kim, M.S.2    Shin, B.A.3    Chay, K.O.4    Ahn, B.W.5    Liu, W.6    Bucana, C.D.7    Gallick, G.E.8    Ellis, L.M.9
  • 240
    • 34248363654 scopus 로고    scopus 로고
    • Green tea catechin inhibits ephrin-A1-mediated cell migration and angiogenesis of human umbilical vein endothelial cells
    • DOI 10.1016/j.jnutbio.2006.07.004, PII S0955286306001859
    • FY Tang EP Chiang CJ Shih 2007 Green tea catechin inhibits ephrin-A1-mediated cell migration and angiogenesis of human umbilical vein endothelial cells The Journal of Nutritional Biochemistry 18 391 399 1:CAS:528:DC%2BD2sXlsFKntb8%3D 17049832 10.1016/j.jnutbio.2006.07.004 (Pubitemid 46736016)
    • (2007) Journal of Nutritional Biochemistry , vol.18 , Issue.6 , pp. 391-399
    • Tang, F.-Y.1    Chiang, E.-P.I.2    Shih, C.-J.3
  • 241
    • 23144447809 scopus 로고    scopus 로고
    • Flavopiridol downregulates hypoxia-mediated hypoxia-inducible factor-1α expression in human glioma cells by a proteasome-independent pathway: Implications for in vivo therapy
    • DOI 10.1215/S1152851704000997
    • EW Newcomb MA Ali T Schnee L Lan Y Lukyanov M Fowkes, et al. 2005 Flavopiridol downregulates hypoxia-mediated hypoxia-inducible factor-1alpha expression in human glioma cells by a proteasome-independent pathway: Implications for in vivo therapy Neuro Oncol 7 225 235 1:CAS:528: DC%2BD2MXos1Cmtr4%3D 16053697 10.1215/S1152851704000997 (Pubitemid 41079132)
    • (2005) Neuro-Oncology , vol.7 , Issue.3 , pp. 225-235
    • Newcomb, E.W.1    Ali, M.A.2    Schnee, T.3    Lan, L.4    Lukyanov, Y.5    Fowkes, M.6    Miller, D.C.7    Zagzag, D.8
  • 243
    • 0037017811 scopus 로고    scopus 로고
    • Inhibitory effect on expression of angiogenic factors by antiangiogenic agents in renal cell carcinoma
    • DOI 10.1038/sj.bjc.6600152
    • H Sasamura A Takahashi N Miyao M Yanase N Masumori H Kitamura, et al. 2002 Inhibitory effect on expression of angiogenic factors by antiangiogenic agents in renal cell carcinoma British Journal of Cancer 86 768 773 1:CAS:528:DC%2BD38XjtVKjsbY%3D 11875741 10.1038/sj.bjc.6600152 (Pubitemid 34250821)
    • (2002) British Journal of Cancer , vol.86 , Issue.5 , pp. 768-773
    • Sasamura, H.1    Takahashi, A.2    Miyao, N.3    Yanase, M.4    Masumori, N.5    Kitamura, H.6    Itoh, N.7    Tsukamoto, T.8
  • 244
    • 0242496947 scopus 로고    scopus 로고
    • Soy Isoflavones and Cancer Prevention
    • DOI 10.1081/CNV-120023773
    • FH Sarkar Y Li 2003 Soy isoflavones and cancer prevention Cancer Invest 21 744 757 1:CAS:528:DC%2BD3sXnvFWgt78%3D 14628433 10.1081/CNV-120023773 (Pubitemid 37377330)
    • (2003) Cancer Investigation , vol.21 , Issue.5 , pp. 744-757
    • Sarkar, F.H.1    Li, Y.2
  • 245
    • 33644847672 scopus 로고    scopus 로고
    • Functional diversity of flavonoids in the inhibition of the proinflammatory NF-kappaB, IRF, and Akt signaling pathways in murine intestinal epithelial cells
    • 1:CAS:528:DC%2BD28XitVOrtrk%3D 16484540
    • PA Ruiz D Haller 2006 Functional diversity of flavonoids in the inhibition of the proinflammatory NF-kappaB, IRF, and Akt signaling pathways in murine intestinal epithelial cells The Journal of Nutrition 136 664 671 1:CAS:528:DC%2BD28XitVOrtrk%3D 16484540
    • (2006) The Journal of Nutrition , vol.136 , pp. 664-671
    • Ruiz, P.A.1    Haller, D.2
  • 246
    • 33645913824 scopus 로고    scopus 로고
    • Antiangiogenic cancer therapies get their act together: Current developments and future prospects of growth factor- and growth factor receptor-targeted approaches
    • 1:CAS:528:DC%2BD28Xjt12msLk%3D 16480425 10.1111/j.1600-0625.2006.00400.x
    • J Gille 2006 Antiangiogenic cancer therapies get their act together: Current developments and future prospects of growth factor- and growth factor receptor-targeted approaches Experimental Dermatology 15 175 186 1:CAS:528:DC%2BD28Xjt12msLk%3D 16480425 10.1111/j.1600-0625.2006.00400.x
    • (2006) Experimental Dermatology , vol.15 , pp. 175-186
    • Gille, J.1
  • 248
    • 7444272077 scopus 로고    scopus 로고
    • Luteolin inhibits vascular endothelial growth factor-induced angiogenesis; inhibition of endothelial cell survival and proliferation by targeting phosphatidylinositol 3′-kinase activity
    • DOI 10.1158/0008-5472.CAN-03-3104
    • E Bagli M Stefaniotou L Morbidelli M Ziche K Psillas C Murphy, et al. 2004 Luteolin inhibits vascular endothelial growth factor-induced angiogenesis; Inhibition of endothelial cell survival and proliferation by targeting phosphatidylinositol 3′-kinase activity Cancer Research 64 7936 7946 1:CAS:528:DC%2BD2cXptFelsrc%3D 15520200 10.1158/0008-5472.CAN-03-3104 (Pubitemid 39446927)
    • (2004) Cancer Research , vol.64 , Issue.21 , pp. 7936-7946
    • Bagli, E.1    Stefaniotou, M.2    Morbidelli, L.3    Ziche, M.4    Psillas, K.5    Murphy, C.6    Fotsis, T.7
  • 250
    • 77950089188 scopus 로고    scopus 로고
    • Flavonoids inhibit hypoxia-induced vascular endothelial growth factor expression by a HIF-1 independent mechanism
    • 1:CAS:528:DC%2BC3cXjvFKmtrc%3D 20153296 10.1016/j.bcp.2010.02.004
    • E Anso A Zuazo M Irigoyen MC Urdaci A Rouzaut JJ Martinez-Irujo 2010 Flavonoids inhibit hypoxia-induced vascular endothelial growth factor expression by a HIF-1 independent mechanism Biochemical Pharmacology 79 1600 1609 1:CAS:528:DC%2BC3cXjvFKmtrc%3D 20153296 10.1016/j.bcp.2010.02.004
    • (2010) Biochemical Pharmacology , vol.79 , pp. 1600-1609
    • Anso, E.1    Zuazo, A.2    Irigoyen, M.3    Urdaci, M.C.4    Rouzaut, A.5    Martinez-Irujo, J.J.6
  • 251
    • 0035430177 scopus 로고    scopus 로고
    • Suppression of angiogenesis, tumor growth, and wound healing by resveratrol, a natural compound in red wine and grapes
    • 1:CAS:528:DC%2BD3MXmsFejsrY%3D 11481234
    • E Brakenhielm R Cao Y Cao 2001 Suppression of angiogenesis, tumor growth, and wound healing by resveratrol, a natural compound in red wine and grapes The FASEB Journal 15 1798 1800 1:CAS:528:DC%2BD3MXmsFejsrY%3D 11481234
    • (2001) The FASEB Journal , vol.15 , pp. 1798-1800
    • Brakenhielm, E.1    Cao, R.2    Cao, Y.3
  • 252
    • 33745667974 scopus 로고    scopus 로고
    • Rosmarinic acid inhibits angiogenesis and its mechanism of action in vitro
    • DOI 10.1016/j.canlet.2005.08.025, PII S0304383505008153
    • SS Huang RL Zheng 2006 Rosmarinic acid inhibits angiogenesis and its mechanism of action in vitro Cancer Letters 239 271 280 1:CAS:528: DC%2BD28Xms1agtbk%3D 16239062 10.1016/j.canlet.2005.08.025 (Pubitemid 43974871)
    • (2006) Cancer Letters , vol.239 , Issue.2 , pp. 271-280
    • Huang, S.-s.1    Zheng, R.-l.2
  • 253
    • 34250829639 scopus 로고    scopus 로고
    • Sanguinarine inhibits VEGF-induced angiogenesis in a fibrin gel matrix
    • 1:CAS:528:DC%2BD2sXmvVartbs%3D
    • G Basini S Bussolati SE Santini F Grasselli 2007 Sanguinarine inhibits VEGF-induced angiogenesis in a fibrin gel matrix BioFactors (Oxford, England) 29 11 18 1:CAS:528:DC%2BD2sXmvVartbs%3D
    • (2007) BioFactors (Oxford, England) , vol.29 , pp. 11-18
    • Basini, G.1    Bussolati, S.2    Santini, S.E.3    Grasselli, F.4
  • 254
    • 59449085306 scopus 로고    scopus 로고
    • Silibinin inhibits established prostate tumor growth, progression, invasion, and metastasis and suppresses tumor angiogenesis and epithelial-mesenchymal transition in transgenic adenocarcinoma of the mouse prostate model mice
    • 1:CAS:528:DC%2BD1cXhsVegtrfO 19047104 10.1158/1078-0432.CCR-08-1309
    • RP Singh K Raina G Sharma R Agarwal 2008 Silibinin inhibits established prostate tumor growth, progression, invasion, and metastasis and suppresses tumor angiogenesis and epithelial-mesenchymal transition in transgenic adenocarcinoma of the mouse prostate model mice Clinical Cancer Research 14 7773 7780 1:CAS:528:DC%2BD1cXhsVegtrfO 19047104 10.1158/1078-0432.CCR-08-1309
    • (2008) Clinical Cancer Research , vol.14 , pp. 7773-7780
    • Singh, R.P.1    Raina, K.2    Sharma, G.3    Agarwal, R.4
  • 255
    • 22744440329 scopus 로고    scopus 로고
    • Suppression of NF-κB and NF-κB-regulated gene expression by sulforaphane and PEITC through IκBα, IKK pathway in human prostate cancer PC-3 cells
    • DOI 10.1038/sj.onc.1208656
    • C Xu G Shen C Chen C Gelinas AN Kong 2005 Suppression of NF-kappaB and NF-kappaB-regulated gene expression by sulforaphane and PEITC through IkappaBalpha, IKK pathway in human prostate cancer PC-3 cells Oncogene 24 4486 4495 1:CAS:528:DC%2BD2MXls1Onu7w%3D 15856023 10.1038/sj.onc.1208656 (Pubitemid 41032612)
    • (2005) Oncogene , vol.24 , Issue.28 , pp. 4486-4495
    • Xu, C.1    Shen, G.2    Chen, C.3    Gelinas, C.4    Kong, A.-N.T.5
  • 256
    • 70449479882 scopus 로고    scopus 로고
    • Sulforaphane inhibits angiogenesis through activation of FOXO transcription factors
    • 1:CAS:528:DC%2BD1MXhsFWlu7vO 19885601
    • R Davis KP Singh R Kurzrock S Shankar 2009 Sulforaphane inhibits angiogenesis through activation of FOXO transcription factors Oncology Reports 22 1473 1478 1:CAS:528:DC%2BD1MXhsFWlu7vO 19885601
    • (2009) Oncology Reports , vol.22 , pp. 1473-1478
    • Davis, R.1    Singh, K.P.2    Kurzrock, R.3    Shankar, S.4
  • 257
    • 0035152252 scopus 로고    scopus 로고
    • Taxotere and vincristine inhibit the secretion of the angiogenesis inducing vascular endothelial growth factor (VEGF) by wild-type and drug-resistant human leukemia T-cell lines
    • 1:CAS:528:DC%2BD3MXovVOqsbw%3D 11724283
    • IA Avramis R Kwock VI Avramis 2001 Taxotere and vincristine inhibit the secretion of the angiogenesis inducing vascular endothelial growth factor (VEGF) by wild-type and drug-resistant human leukemia T-cell lines Anticancer Research 21 2281 2286 1:CAS:528:DC%2BD3MXovVOqsbw%3D 11724283
    • (2001) Anticancer Research , vol.21 , pp. 2281-2286
    • Avramis, I.A.1    Kwock, R.2    Avramis, V.I.3
  • 258
    • 77954143922 scopus 로고    scopus 로고
    • Gamma-tocotrienol modulates the paracrine secretion of VEGF induced by cobalt(II) chloride via ERK signaling pathway in gastric adenocarcinoma SGC-7901 cell line
    • 1:CAS:528:DC%2BC3cXosV2ksr8%3D 20452389 10.1016/j.tox.2010.05.002
    • S Bi JR Liu Y Li Q Wang HK Liu YG Yan, et al. 2010 Gamma-tocotrienol modulates the paracrine secretion of VEGF induced by cobalt(II) chloride via ERK signaling pathway in gastric adenocarcinoma SGC-7901 cell line Toxicology 274 27 33 1:CAS:528:DC%2BC3cXosV2ksr8%3D 20452389 10.1016/j.tox.2010.05.002
    • (2010) Toxicology , vol.274 , pp. 27-33
    • Bi, S.1    Liu, J.R.2    Li, Y.3    Wang, Q.4    Liu, H.K.5    Yan, Y.G.6
  • 259
    • 77954203666 scopus 로고    scopus 로고
    • Antiangiogenic activity of ursolic acid
    • 1:CAS:528:DC%2BC3cXpsFOisLY%3D 20462855 10.1177/1534735410367647
    • M Kanjoormana G Kuttan 2010 Antiangiogenic activity of ursolic acid Integrative Cancer Therapies 9 224 235 1:CAS:528:DC%2BC3cXpsFOisLY%3D 20462855 10.1177/1534735410367647
    • (2010) Integrative Cancer Therapies , vol.9 , pp. 224-235
    • Kanjoormana, M.1    Kuttan, G.2
  • 260
    • 65349134218 scopus 로고    scopus 로고
    • Vanillin suppresses metastatic potential of human cancer cells through PI3K inhibition and decreases angiogenesis in vivo
    • 1:CAS:528:DC%2BD1MXivFOmtr4%3D 19368348 10.1021/jf803366f
    • K Lirdprapamongkol JP Kramb T Suthiphongchai R Surarit C Srisomsap G Dannhardt, et al. 2009 Vanillin suppresses metastatic potential of human cancer cells through PI3K inhibition and decreases angiogenesis in vivo Journal of Agricultural and Food Chemistry 57 3055 3063 1:CAS:528:DC%2BD1MXivFOmtr4%3D 19368348 10.1021/jf803366f
    • (2009) Journal of Agricultural and Food Chemistry , vol.57 , pp. 3055-3063
    • Lirdprapamongkol, K.1    Kramb, J.P.2    Suthiphongchai, T.3    Surarit, R.4    Srisomsap, C.5    Dannhardt, G.6
  • 261
    • 0033947601 scopus 로고    scopus 로고
    • The pro- or anti-apoptotic function of NF-κB is determined by the nature of the apoptotic stimulus
    • DOI 10.1046/j.1432-1327.2000.01421.x
    • B Kaltschmidt C Kaltschmidt TG Hofmann SP Hehner W Droge ML Schmitz 2000 The pro- or anti-apoptotic function of NF-kappaB is determined by the nature of the apoptotic stimulus European Journal of Biochemistry 267 3828 3835 1:CAS:528:DC%2BD3cXksVKgur0%3D 10849002 10.1046/j.1432-1327.2000.01421.x (Pubitemid 30423046)
    • (2000) European Journal of Biochemistry , vol.267 , Issue.12 , pp. 3828-3835
    • Kaltschmidt, B.1    Kaltschmidt, C.2    Hofmann, T.G.3    Hehner, S.P.4    Droge, W.5    Schmitz, M.L.6
  • 262
    • 0032170032 scopus 로고    scopus 로고
    • Estrogenic effects of genistein on the growth of estrogen receptor-positive human breast cancer (MCF-7) cells in vitro and in vivo
    • 1:CAS:528:DyaK1cXlvVyru74%3D 9731492
    • CY Hsieh RC Santell SZ Haslam WG Helferich 1998 Estrogenic effects of genistein on the growth of estrogen receptor-positive human breast cancer (MCF-7) cells in vitro and in vivo Cancer Research 58 3833 3838 1:CAS:528:DyaK1cXlvVyru74%3D 9731492
    • (1998) Cancer Research , vol.58 , pp. 3833-3838
    • Hsieh, C.Y.1    Santell, R.C.2    Haslam, S.Z.3    Helferich, W.G.4
  • 263
    • 0034785067 scopus 로고    scopus 로고
    • Dietary genistin stimulates growth of estrogen-dependent breast cancer tumors similar to that observed with genistein
    • 1:CAS:528:DC%2BD3MXnsFKmtLo%3D 11577007 10.1093/carcin/22.10.1667
    • CD Allred YH Ju KF Allred J Chang WG Helferich 2001 Dietary genistin stimulates growth of estrogen-dependent breast cancer tumors similar to that observed with genistein Carcinogenesis 22 1667 1673 1:CAS:528: DC%2BD3MXnsFKmtLo%3D 11577007 10.1093/carcin/22.10.1667
    • (2001) Carcinogenesis , vol.22 , pp. 1667-1673
    • Allred, C.D.1    Ju, Y.H.2    Allred, K.F.3    Chang, J.4    Helferich, W.G.5
  • 264
    • 0030333304 scopus 로고    scopus 로고
    • Epidemiology of susceptibility to breast cancer
    • 1:STN:280:DyaK2s%2FltFanuw%3D%3D 8895988
    • BS Hulka 1996 Epidemiology of susceptibility to breast cancer Progress in Clinical and Biological Research 395 159 174 1:STN:280:DyaK2s%2FltFanuw%3D%3D 8895988
    • (1996) Progress in Clinical and Biological Research , vol.395 , pp. 159-174
    • Hulka, B.S.1
  • 265
    • 33748988463 scopus 로고    scopus 로고
    • Addressing the soy and breast cancer relationship: Review, commentary, and workshop proceedings
    • DOI 10.1093/jnci/djj356
    • M Messina W McCaskill-Stevens JW Lampe 2006 Addressing the soy and breast cancer relationship: Review, commentary, and workshop proceedings Journal of the National Cancer Institute 98 1275 1284 16985246 10.1093/jnci/djj356 (Pubitemid 44530723)
    • (2006) Journal of the National Cancer Institute , vol.98 , Issue.18 , pp. 1275-1284
    • Messina, M.1    McCaskill-Stevens, W.2    Lampe, J.W.3
  • 266
    • 34250197957 scopus 로고    scopus 로고
    • Folate and colorectal cancer: An evidence-based critical review
    • DOI 10.1002/mnfr.200600191
    • YI Kim 2007 Folate and colorectal cancer: An evidence-based critical review Molecular Nutrition & Food Research 51 267 292 1:CAS:528: DC%2BD2sXjs1WqtLs%3D 10.1002/mnfr.200600191 (Pubitemid 47083662)
    • (2007) Molecular Nutrition and Food Research , vol.51 , Issue.3 , pp. 267-292
    • Kim, Y.-I.1
  • 267
    • 0037182755 scopus 로고    scopus 로고
    • The c-Rel transcription factor can both induce and inhibit apoptosis in the same cells via the upregulation of MnSOD
    • DOI 10.1038/sj.onc.1205536
    • D Bernard D Monte B Vandenbunder C Abbadie 2002 The c-Rel transcription factor can both induce and inhibit apoptosis in the same cells via the upregulation of MnSOD Oncogene 21 4392 4402 1:CAS:528:DC%2BD38XkslKnt7Y%3D 12080470 10.1038/sj.onc.1205536 (Pubitemid 34774842)
    • (2002) Oncogene , vol.21 , Issue.28 , pp. 4392-4402
    • Bernard, D.1    Monte, D.2    Vandenbunder, B.3    Abbadie, C.4
  • 268
    • 0033605572 scopus 로고    scopus 로고
    • 1 arrest and apoptosis in a pro-B cell line
    • DOI 10.1074/jbc.274.13.8708
    • AM Sheehy MS Schlissel 1999 Overexpression of RelA causes G1 arrest and apoptosis in a pro-B cell line The Journal of Biological Chemistry 274 8708 8716 1:CAS:528:DyaK1MXitFyrtrk%3D 10085110 10.1074/jbc.274.13.8708 (Pubitemid 29164667)
    • (1999) Journal of Biological Chemistry , vol.274 , Issue.13 , pp. 8708-8716
    • Sheehy, A.M.1    Schlissel, M.S.2
  • 269
    • 50449099855 scopus 로고    scopus 로고
    • Inhibition of IkappaB kinase-nuclear factor-kappaB signaling pathway by 3,5-bis(2-flurobenzylidene)piperidin-4-one (EF24), a novel monoketone analog of curcumin
    • 1:CAS:528:DC%2BD1cXhtVClt7jJ 18577686 10.1124/mol.108.046201
    • AL Kasinski Y Du SL Thomas J Zhao SY Sun FR Khuri, et al. 2008 Inhibition of IkappaB kinase-nuclear factor-kappaB signaling pathway by 3,5-bis(2-flurobenzylidene)piperidin-4-one (EF24), a novel monoketone analog of curcumin Molecular Pharmacology 74 654 661 1:CAS:528:DC%2BD1cXhtVClt7jJ 18577686 10.1124/mol.108.046201
    • (2008) Molecular Pharmacology , vol.74 , pp. 654-661
    • Kasinski, A.L.1    Du, Y.2    Thomas, S.L.3    Zhao, J.4    Sun, S.Y.5    Khuri, F.R.6
  • 270
    • 9444225949 scopus 로고    scopus 로고
    • Alterations in receptor expression or agonist concentration change the pathways gastrin-releasing peptide receptor uses to regulate extracellular signal-regulated kinase
    • DOI 10.1124/mol.104.001206
    • CC Chen MP Chow WC Huang YC Lin YJ Chang 2004 Flavonoids inhibit tumor necrosis factor-alpha-induced up-regulation of intercellular adhesion molecule-1 (ICAM-1) in respiratory epithelial cells through activator protein-1 and nuclear factor-kappaB: Structure-activity relationships Molecular Pharmacology 66 683 693 1:CAS:528:DC%2BD2cXhtVOit7jO 15322261 10.1124/mol.104.001206 (Pubitemid 39564790)
    • (2004) Molecular Pharmacology , vol.66 , Issue.6 , pp. 1625-1634
    • Chen, P.-W.1    Kroog, G.S.2
  • 271
    • 48549105216 scopus 로고    scopus 로고
    • Berberine modifies cysteine 179 of IkappaBalpha kinase, suppresses nuclear factor-kappaB-regulated antiapoptotic gene products, and potentiates apoptosis
    • 1:CAS:528:DC%2BD1cXnvFyjtL8%3D 18593939 10.1158/0008-5472.CAN-08-0511
    • MK Pandey B Sung AB Kunnumakkara G Sethi MM Chaturvedi BB Aggarwal 2008 Berberine modifies cysteine 179 of IkappaBalpha kinase, suppresses nuclear factor-kappaB-regulated antiapoptotic gene products, and potentiates apoptosis Cancer Research 68 5370 5379 1:CAS:528:DC%2BD1cXnvFyjtL8%3D 18593939 10.1158/0008-5472.CAN-08-0511
    • (2008) Cancer Research , vol.68 , pp. 5370-5379
    • Pandey, M.K.1    Sung, B.2    Kunnumakkara, A.B.3    Sethi, G.4    Chaturvedi, M.M.5    Aggarwal, B.B.6
  • 272
    • 24144451076 scopus 로고    scopus 로고
    • Green tea polyphenols modulate secretion of urokinase plasminogen activator (uPA) and inhibit invasive behavior of breast cancer cells
    • 1:CAS:528:DC%2BD2MXhtVemsbbK 16091006 10.1207/s15327914nc52019
    • V Slivova G Zaloga SJ DeMichele P Mukerji YS Huang R Siddiqui, et al. 2005 Green tea polyphenols modulate secretion of urokinase plasminogen activator (uPA) and inhibit invasive behavior of breast cancer cells Nutrition and Cancer 52 66 73 1:CAS:528:DC%2BD2MXhtVemsbbK 16091006 10.1207/s15327914nc52019
    • (2005) Nutrition and Cancer , vol.52 , pp. 66-73
    • Slivova, V.1    Zaloga, G.2    Demichele, S.J.3    Mukerji, P.4    Huang, Y.S.5    Siddiqui, R.6
  • 273
    • 34347361698 scopus 로고    scopus 로고
    • Fisetin, an inhibitor of cyclin-dependent kinase 6, down-regulates nuclear factor-κB-regulated cell proliferation, antiapoptotic and metastatic gene products through the suppression of TAK-1 and receptor-interacting protein-regulated IκBα kinase activation
    • DOI 10.1124/mol.107.034512
    • B Sung MK Pandey BB Aggarwal 2007 Fisetin, an inhibitor of cyclin-dependent kinase 6, down-regulates nuclear factor-kappaB-regulated cell proliferation, antiapoptotic and metastatic gene products through the suppression of TAK-1 and receptor-interacting protein-regulated IkappaBalpha kinase activation Molecular Pharmacology 71 1703 1714 1:CAS:528: DC%2BD2sXmt1Wqur4%3D 17387141 10.1124/mol.107.034512 (Pubitemid 47010923)
    • (2007) Molecular Pharmacology , vol.71 , Issue.6 , pp. 1703-1714
    • Sung, B.1    Pandey, M.K.2    Aggarwal, B.B.3
  • 274
    • 34548081194 scopus 로고    scopus 로고
    • Cyclin-dependent kinase inhibitor, flavopiridol, induces apoptosis and inhibits tumor growth in drug-resistant Osteosarcoma and Ewing's family tumor cells
    • DOI 10.1002/ijc.22820
    • Y Li K Tanaka X Li T Okada T Nakamura M Takasaki, et al. 2007 Cyclin-dependent kinase inhibitor, flavopiridol, induces apoptosis and inhibits tumor growth in drug-resistant osteosarcoma and Ewing's family tumor cells International Journal of Cancer 121 1212 1218 1:CAS:528:DC%2BD2sXhtVSmt7fL 10.1002/ijc.22820 (Pubitemid 47293787)
    • (2007) International Journal of Cancer , vol.121 , Issue.6 , pp. 1212-1218
    • Li, Y.1    Tanaka, K.2    Li, X.3    Okada, T.4    Nakamura, T.5    Takasaki, M.6    Yamamoto, S.7    Oda, Y.8    Tsuneyoshi, M.9    Iwamoto, Y.10
  • 275
    • 78651107917 scopus 로고    scopus 로고
    • Nicotine-induced human breast cancer cell proliferation attenuated by garcinol through down-regulation of the nicotinic receptor and cyclin D3 proteins
    • in press
    • Chen, C.S., Lee, C.H., Hsieh, C.D., Ho, C.T., Pan, M.H., Huang, C.S., et al. (2010). Nicotine-induced human breast cancer cell proliferation attenuated by garcinol through down-regulation of the nicotinic receptor and cyclin D3 proteins. Breast Cancer Research and Treatment, in press
    • (2010) Breast Cancer Research and Treatment
    • Chen, C.S.1    Lee, C.H.2    Hsieh, C.D.3    Ho, C.T.4    Pan, M.H.5    Huang, C.S.6
  • 276
    • 79954432555 scopus 로고    scopus 로고
    • Noscapine induces mitochondria-mediated apoptosis in gastric cancer cells in vitro and in vivo
    • in press
    • Liu, M., Luo, X.J., Liao, F., Lei, X.F., & Dong, W.G. (2010). Noscapine induces mitochondria-mediated apoptosis in gastric cancer cells in vitro and in vivo. Cancer Chemotherapy and Pharmacology, in press
    • (2010) Cancer Chemotherapy and Pharmacology
    • Liu, M.1    Luo, X.J.2    Liao, F.3    Lei, X.F.4    Dong, W.G.5
  • 277
    • 67649946192 scopus 로고    scopus 로고
    • Quercetin inhibit human SW480 colon cancer growth in association with inhibition of cyclin D1 and survivin expression through Wnt/beta-catenin signaling pathway
    • 1:CAS:528:DC%2BD1MXnvVOmt7Y%3D 19440933 10.1080/07357900802337191
    • BE Shan MX Wang RQ Li 2009 Quercetin inhibit human SW480 colon cancer growth in association with inhibition of cyclin D1 and survivin expression through Wnt/beta-catenin signaling pathway Cancer Investigation 27 604 612 1:CAS:528:DC%2BD1MXnvVOmt7Y%3D 19440933 10.1080/07357900802337191
    • (2009) Cancer Investigation , vol.27 , pp. 604-612
    • Shan, B.E.1    Wang, M.X.2    Li, R.Q.3
  • 278
    • 0029133499 scopus 로고
    • Influence of anethole treatment on the tumour induced by Ehrlich ascites carcinoma cells in paw of Swiss albino mice
    • 1:STN:280:DyaK28%2FksFWluw%3D%3D 7549823 10.1097/00008469-199508000-00006
    • MM al-Harbi S Qureshi M Raza MM Ahmed AB Giangreco AH Shah 1995 Influence of anethole treatment on the tumour induced by Ehrlich ascites carcinoma cells in paw of Swiss albino mice European Journal of Cancer Prevention 4 307 318 1:STN:280:DyaK28%2FksFWluw%3D%3D 7549823 10.1097/00008469-199508000-00006
    • (1995) European Journal of Cancer Prevention , vol.4 , pp. 307-318
    • Al-Harbi, M.M.1    Qureshi, S.2    Raza, M.3    Ahmed, M.M.4    Giangreco, A.B.5    Shah, A.H.6
  • 279
    • 62549160369 scopus 로고    scopus 로고
    • Anti-invasive activity of sanguinarine through modulation of tight junctions and matrix metalloproteinase activities in MDA-MB-231 human breast carcinoma cells
    • 1:CAS:528:DC%2BD1MXjsFajsb4%3D 10.1016/j.cbi.2008.11.009
    • YH Choi WY Choi SH Hong SO Kim GY Kim WH Lee, et al. 2009 Anti-invasive activity of sanguinarine through modulation of tight junctions and matrix metalloproteinase activities in MDA-MB-231 human breast carcinoma cells Chemico-Biological Interaction 179 185 191 1:CAS:528:DC%2BD1MXjsFajsb4%3D 10.1016/j.cbi.2008.11.009
    • (2009) Chemico-Biological Interaction , vol.179 , pp. 185-191
    • Choi, Y.H.1    Choi, W.Y.2    Hong, S.H.3    Kim, S.O.4    Kim, G.Y.5    Lee, W.H.6
  • 280
    • 0032510164 scopus 로고    scopus 로고
    • Ursolic acid-induced down-regulation of MMP-9 gene is mediated through the nuclear translocation of glucocorticoid receptor in HT1080 human fibrosarcoma cells
    • 1:CAS:528:DyaK1cXhtlGgt7s%3D 9488041 10.1038/sj.onc.1201587
    • HJ Cha MT Park HY Chung ND Kim H Sato M Seiki, et al. 1998 Ursolic acid-induced down-regulation of MMP-9 gene is mediated through the nuclear translocation of glucocorticoid receptor in HT1080 human fibrosarcoma cells Oncogene 16 771 778 1:CAS:528:DyaK1cXhtlGgt7s%3D 9488041 10.1038/sj.onc.1201587
    • (1998) Oncogene , vol.16 , pp. 771-778
    • Cha, H.J.1    Park, M.T.2    Chung, H.Y.3    Kim, N.D.4    Sato, H.5    Seiki, M.6


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