Regulation of insulin secretion: Role of mitochondrial signalling

Diabetologia

Volumn 53, Issue 6, 2010, Pages 1019-1032

  Jitrapakdee, S ^a   Wutthisathapornchai, A ^a   Wallace, J C ^b   MacDonald, M J ^c  

^a MAHIDOL UNIVERSITY   (Thailand)

^b UNIVERSITY OF ADELAIDE   (Australia)

^c UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

Author keywords

Coupling factors; Glucose stimulated insulin secretion; Insulin secretion; Mitochondrial metabolism; Pyruvate cycling; Review

Indexed keywords

2 OXOGLUTARIC ACID; ADENOSINE TRIPHOSPHATE; CALCIUM; CITRIC ACID; GLUCOSE; GLUTAMATE DEHYDROGENASE; GUANOSINE TRIPHOSPHATE; INSULIN; MALIC ACID; NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; PYRUVATE CARBOXYLASE; PYRUVIC ACID; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; UNCOUPLING PROTEIN;

CALCIUM CELL LEVEL; CARBOXYLATION; CITRIC ACID CYCLE; DEHYDROGENATION; DISEASE SEVERITY; DOWN REGULATION; ENZYME REGULATION; GLUCOSE BLOOD LEVEL; GLUCOSE HOMEOSTASIS; GLUCOSE METABOLISM; HUMAN; HYPERGLYCEMIA; HYPERLIPIDEMIA; INSULIN RELEASE; MITOCHONDRIAL RESPIRATION; MITOCHONDRION; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; OBESITY; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; REVIEW; SIGNAL TRANSDUCTION;

ANIMALS; BLOOD GLUCOSE; HUMANS; INSULIN; INSULIN-SECRETING CELLS; MITOCHONDRIA; PYRUVATE CARBOXYLASE; SIGNAL TRANSDUCTION;

EID: 77952096424     PISSN: 0012186X     EISSN: 14320428     Source Type: Journal    
DOI: 10.1007/s00125-010-1685-0     Document Type: Review

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