메뉴 건너뛰기




Volumn 1813, Issue 7, 2011, Pages 1269-1278

Metabolic control of mitochondrial biogenesis through the PGC-1 family regulatory network

Author keywords

Coactivator; Gene expression; Mitochondria; Regulation; Respiration; Transcription

Indexed keywords

ADENYLATE KINASE; ESTROGEN RELATED RECEPTOR ALPHA; MEMBRANE PROTEIN; ORPHAN NUCLEAR RECEPTOR; PROTEIN PGC 1; PROTEIN PGC 1ALPHA; PROTEIN PGC 1BETA; PROTEIN PRC; SIRTUIN 1; TRANSCRIPTION FACTOR NRF1; TRANSCRIPTION FACTOR NRF2; UNCLASSIFIED DRUG;

EID: 79957960940     PISSN: 01674889     EISSN: 18792596     Source Type: Journal    
DOI: 10.1016/j.bbamcr.2010.09.019     Document Type: Review
Times cited : (998)

References (102)
  • 1
    • 0021891869 scopus 로고
    • The mitochondrial electron transport chain and oxidative phosphorylation system
    • Hatefi Y. The mitochondrial electron transport chain and oxidative phosphorylation system. Annu. Rev. Biochem. 1985, 54:1015-1069.
    • (1985) Annu. Rev. Biochem. , vol.54 , pp. 1015-1069
    • Hatefi, Y.1
  • 2
    • 0025343842 scopus 로고
    • Regulation of oxidative phosphorylation in the mammalian cell
    • Balaban R.S. Regulation of oxidative phosphorylation in the mammalian cell. Am. J. Physiol. Cell Physiol. 1990, 258:C377-C389.
    • (1990) Am. J. Physiol. Cell Physiol. , vol.258
    • Balaban, R.S.1
  • 3
    • 0033525788 scopus 로고    scopus 로고
    • Mitochondrial evolution
    • Gray M.W., Burgess G., Lang B.F. Mitochondrial evolution. Science 1999, 283:1476-1481.
    • (1999) Science , vol.283 , pp. 1476-1481
    • Gray, M.W.1    Burgess, G.2    Lang, B.F.3
  • 4
    • 0033060854 scopus 로고    scopus 로고
    • The mitochondrial genome: structure, transcription, translation and replication
    • Taanman J.W. The mitochondrial genome: structure, transcription, translation and replication. Biochim. Biophys. Acta Bioenerg. 1999, 1410:103-123.
    • (1999) Biochim. Biophys. Acta Bioenerg. , vol.1410 , pp. 103-123
    • Taanman, J.W.1
  • 5
    • 23844558266 scopus 로고    scopus 로고
    • A mitochondrial paradigm of metabolic and degenerative diseases, aging, and cancer: a dawn for evolutionary medicine
    • Wallace D.C. A mitochondrial paradigm of metabolic and degenerative diseases, aging, and cancer: a dawn for evolutionary medicine. Annu. Rev. Genet. 2005, 39:359-407.
    • (2005) Annu. Rev. Genet. , vol.39 , pp. 359-407
    • Wallace, D.C.1
  • 6
    • 33845744837 scopus 로고    scopus 로고
    • Initiation and beyond: multiple functions of the human mitochondrial transcription machinery
    • Bonawitz N.D., Clayton D.A., Shadel G.S. Initiation and beyond: multiple functions of the human mitochondrial transcription machinery. Mol. Cell 2006, 24:813-825.
    • (2006) Mol. Cell , vol.24 , pp. 813-825
    • Bonawitz, N.D.1    Clayton, D.A.2    Shadel, G.S.3
  • 7
    • 42049114034 scopus 로고    scopus 로고
    • Transcriptional paradigms in mammalian mitochondrial biogenesis and function
    • Scarpulla R.C. Transcriptional paradigms in mammalian mitochondrial biogenesis and function. Physiol. Rev. 2008, 88:611-638.
    • (2008) Physiol. Rev. , vol.88 , pp. 611-638
    • Scarpulla, R.C.1
  • 9
    • 56349124605 scopus 로고    scopus 로고
    • Assembly of the oxidative phosphorylation system in humans: what we have learned by studying its defects
    • Fernandez-Vizarra E., Tiranti V., Zeviani M. Assembly of the oxidative phosphorylation system in humans: what we have learned by studying its defects. Biochim. Biophys. Acta 2009, 1793:200-211.
    • (2009) Biochim. Biophys. Acta , vol.1793 , pp. 200-211
    • Fernandez-Vizarra, E.1    Tiranti, V.2    Zeviani, M.3
  • 11
    • 0014198263 scopus 로고
    • Biochemical adaptations in muscle. Effects of exercise on mitochondrial oxygen uptake and respiratory enzyme activity in skeletal muscle
    • Holloszy J.O. Biochemical adaptations in muscle. Effects of exercise on mitochondrial oxygen uptake and respiratory enzyme activity in skeletal muscle. J. Biol. Chem. 1967, 242:2278-2282.
    • (1967) J. Biol. Chem. , vol.242 , pp. 2278-2282
    • Holloszy, J.O.1
  • 14
    • 0016636764 scopus 로고
    • Effect of thyroid hormone administration on synthesis and degradation of cytochrome c in rat liver
    • Booth F.W., Holloszy J.O. Effect of thyroid hormone administration on synthesis and degradation of cytochrome c in rat liver. Arch. Biochem. Biophys. 1975, 167:674-677.
    • (1975) Arch. Biochem. Biophys. , vol.167 , pp. 674-677
    • Booth, F.W.1    Holloszy, J.O.2
  • 15
    • 0034668852 scopus 로고    scopus 로고
    • Mitochondrial uncoupling proteins: from mitochondria to the regulation of energy balance
    • Ricquier D., Bouillaud F. Mitochondrial uncoupling proteins: from mitochondria to the regulation of energy balance. J. Physiol. 2000, 529:3-10.
    • (2000) J. Physiol. , vol.529 , pp. 3-10
    • Ricquier, D.1    Bouillaud, F.2
  • 16
    • 0347989317 scopus 로고    scopus 로고
    • Brown adipose tissue: function and physiological significance
    • Cannon B., Nedergaard J. Brown adipose tissue: function and physiological significance. Physiol. Rev. 2004, 84:277-359.
    • (2004) Physiol. Rev. , vol.84 , pp. 277-359
    • Cannon, B.1    Nedergaard, J.2
  • 17
    • 33645011201 scopus 로고    scopus 로고
    • Nuclear control of respiratory gene expression in mammalian cells
    • Scarpulla R.C. Nuclear control of respiratory gene expression in mammalian cells. J. Cell. Biochem. 2006, 97:673-683.
    • (2006) J. Cell. Biochem. , vol.97 , pp. 673-683
    • Scarpulla, R.C.1
  • 18
    • 1542373685 scopus 로고    scopus 로고
    • Transcriptional regulatory circuits controlling mitochondrial biogenesis and function
    • Kelly D.P., Scarpulla R.C. Transcriptional regulatory circuits controlling mitochondrial biogenesis and function. Genes Dev. 2004, 18:357-368.
    • (2004) Genes Dev. , vol.18 , pp. 357-368
    • Kelly, D.P.1    Scarpulla, R.C.2
  • 19
    • 26444545461 scopus 로고    scopus 로고
    • Is nuclear respiratory factor 2 a master transcriptional coordinator for all ten nuclear-encoded cytochrome c oxidase subunits in neurons?
    • Ongwijitwat S., Wong-Riley M.T. Is nuclear respiratory factor 2 a master transcriptional coordinator for all ten nuclear-encoded cytochrome c oxidase subunits in neurons?. Gene 2005, 360:65-77.
    • (2005) Gene , vol.360 , pp. 65-77
    • Ongwijitwat, S.1    Wong-Riley, M.T.2
  • 20
    • 41249086496 scopus 로고    scopus 로고
    • Nuclear respiratory factor 1 regulates all ten nuclear-encoded subunits of cytochrome c oxidase in neurons
    • Dhar S.S., Ongwijitwat S., Wong-Riley M.T. Nuclear respiratory factor 1 regulates all ten nuclear-encoded subunits of cytochrome c oxidase in neurons. J. Biol. Chem. 2008, 283:3120-3129.
    • (2008) J. Biol. Chem. , vol.283 , pp. 3120-3129
    • Dhar, S.S.1    Ongwijitwat, S.2    Wong-Riley, M.T.3
  • 21
    • 0028049078 scopus 로고
    • Differential regulation of respiratory chain subunits by a CREB-dependent signal transduction pathway. Role of cyclic AMP in cytochrome c and COXIV gene expression
    • Gopalakrishnan L., Scarpulla R.C. Differential regulation of respiratory chain subunits by a CREB-dependent signal transduction pathway. Role of cyclic AMP in cytochrome c and COXIV gene expression. J. Biol. Chem. 1994, 269:105-113.
    • (1994) J. Biol. Chem. , vol.269 , pp. 105-113
    • Gopalakrishnan, L.1    Scarpulla, R.C.2
  • 22
    • 0034724861 scopus 로고    scopus 로고
    • Sequential serum-dependent activation of CREB and NRF-1 leads to enhanced mitochondrial respiration through the induction of cytochrome c
    • Herzig R.P., Scacco S., Scarpulla R.C. Sequential serum-dependent activation of CREB and NRF-1 leads to enhanced mitochondrial respiration through the induction of cytochrome c. J. Biol. Chem. 2000, 275:13134-13141.
    • (2000) J. Biol. Chem. , vol.275 , pp. 13134-13141
    • Herzig, R.P.1    Scacco, S.2    Scarpulla, R.C.3
  • 23
    • 33749630419 scopus 로고    scopus 로고
    • PGC-1-related coactivator (PRC): immediate early expression and characterization of a CREB/NRF-1 binding domain associated with cytochrome c promoter occupancy and respiratory growth
    • Vercauteren K., Pasko R.A., Gleyzer N., Marino V.M., Scarpulla R.C. PGC-1-related coactivator (PRC): immediate early expression and characterization of a CREB/NRF-1 binding domain associated with cytochrome c promoter occupancy and respiratory growth. Mol. Cell. Biol. 2006, 26:7409-7419.
    • (2006) Mol. Cell. Biol. , vol.26 , pp. 7409-7419
    • Vercauteren, K.1    Pasko, R.A.2    Gleyzer, N.3    Marino, V.M.4    Scarpulla, R.C.5
  • 24
    • 0031041464 scopus 로고    scopus 로고
    • Regulation of murine cytochrome oxidase Vb gene expression in different tissues and during myogenesis-role of a YY-1 factor-binding negative enhancer
    • Basu A., Lenka N., Mullick J., Avadhani N.G. Regulation of murine cytochrome oxidase Vb gene expression in different tissues and during myogenesis-role of a YY-1 factor-binding negative enhancer. J. Biol. Chem. 1997, 272:5899-5908.
    • (1997) J. Biol. Chem. , vol.272 , pp. 5899-5908
    • Basu, A.1    Lenka, N.2    Mullick, J.3    Avadhani, N.G.4
  • 25
    • 0030899375 scopus 로고    scopus 로고
    • Structural organization and promoter analysis of the bovine cytochrome c oxidase subunit VIIc gene-a functional role for YY1
    • Seelan R.S., Grossman L.I. Structural organization and promoter analysis of the bovine cytochrome c oxidase subunit VIIc gene-a functional role for YY1. J. Biol. Chem. 1997, 272:10175-10181.
    • (1997) J. Biol. Chem. , vol.272 , pp. 10175-10181
    • Seelan, R.S.1    Grossman, L.I.2
  • 26
    • 0028799005 scopus 로고
    • Structural characterization and regulatory element analysis of the heart isoform of cytochrome c oxidase VIa
    • Wan B., Moreadith R.W. Structural characterization and regulatory element analysis of the heart isoform of cytochrome c oxidase VIa. J. Biol. Chem. 1995, 270:26433-26440.
    • (1995) J. Biol. Chem. , vol.270 , pp. 26433-26440
    • Wan, B.1    Moreadith, R.W.2
  • 27
    • 45549087482 scopus 로고    scopus 로고
    • Nuclear respiratory factor 1 controls myocyte enhancer factor 2A transcription to provide a mechanism for coordinate expression of respiratory chain subunits
    • Ramachandran B., Yu G., Gulick T. Nuclear respiratory factor 1 controls myocyte enhancer factor 2A transcription to provide a mechanism for coordinate expression of respiratory chain subunits. J. Biol. Chem. 2008, 283:11935-11946.
    • (2008) J. Biol. Chem. , vol.283 , pp. 11935-11946
    • Ramachandran, B.1    Yu, G.2    Gulick, T.3
  • 28
    • 4644231528 scopus 로고    scopus 로고
    • Nuclear receptor signaling and cardiac energetics
    • Huss J.M., Kelly D.P. Nuclear receptor signaling and cardiac energetics. Circ. Res. 2004, 95:568-578.
    • (2004) Circ. Res. , vol.95 , pp. 568-578
    • Huss, J.M.1    Kelly, D.P.2
  • 31
    • 53849088227 scopus 로고    scopus 로고
    • Transcriptional control of energy homeostasis by the estrogen-related receptors
    • Giguere V. Transcriptional control of energy homeostasis by the estrogen-related receptors. Endocr. Rev. 2008, 29:677-696.
    • (2008) Endocr. Rev. , vol.29 , pp. 677-696
    • Giguere, V.1
  • 32
    • 0037439054 scopus 로고    scopus 로고
    • C-MYC apoptotic function is mediated by NRF-1 target genes
    • Morrish F., Giedt C., Hockenbery D. C-MYC apoptotic function is mediated by NRF-1 target genes. Genes Dev. 2003, 17:240-255.
    • (2003) Genes Dev. , vol.17 , pp. 240-255
    • Morrish, F.1    Giedt, C.2    Hockenbery, D.3
  • 34
    • 34247614521 scopus 로고    scopus 로고
    • HIF-1 inhibits mitochondrial biogenesis and cellular respiration in VHL-deficient renal cell carcinoma by repression of C-MYC activity
    • Zhang H., Gao P., Fukuda R., Kumar G., Krishnamachary B., Zeller K.I., Dang C.V., Semenza G.L. HIF-1 inhibits mitochondrial biogenesis and cellular respiration in VHL-deficient renal cell carcinoma by repression of C-MYC activity. Cancer Cell 2007, 11:407-420.
    • (2007) Cancer Cell , vol.11 , pp. 407-420
    • Zhang, H.1    Gao, P.2    Fukuda, R.3    Kumar, G.4    Krishnamachary, B.5    Zeller, K.I.6    Dang, C.V.7    Semenza, G.L.8
  • 35
    • 0029061518 scopus 로고
    • Identification of the promoter of the human von Hippel-Lindau disease tumor suppressor gene
    • Kuzmin I., Duh F.M., Latif F., Geil L., Zbar B., Lerman M.I. Identification of the promoter of the human von Hippel-Lindau disease tumor suppressor gene. Oncogene 1995, 10:2185-2194.
    • (1995) Oncogene , vol.10 , pp. 2185-2194
    • Kuzmin, I.1    Duh, F.M.2    Latif, F.3    Geil, L.4    Zbar, B.5    Lerman, M.I.6
  • 36
    • 0031011211 scopus 로고    scopus 로고
    • A mouse model for mitochondrial myopathy and cardiomyopathy resulting from a deficiency in the heart/muscle isoform of the adenine nucleotide translocator
    • Graham B.H., Waymire K.G., Cottrell B., Trounce I.A., MacGregor G.R., Wallace D.C. A mouse model for mitochondrial myopathy and cardiomyopathy resulting from a deficiency in the heart/muscle isoform of the adenine nucleotide translocator. Nat. Genet. 1997, 16:226-234.
    • (1997) Nat. Genet. , vol.16 , pp. 226-234
    • Graham, B.H.1    Waymire, K.G.2    Cottrell, B.3    Trounce, I.A.4    MacGregor, G.R.5    Wallace, D.C.6
  • 37
    • 0033553435 scopus 로고    scopus 로고
    • Up-regulation of nuclear and mitochondrial genes in the skeletal muscle of mice lacking the heart muscle isoform of the adenine nucleotide translocator
    • Murdock D.G., Boone B.E., Esposito L.A., Wallace D.C. Up-regulation of nuclear and mitochondrial genes in the skeletal muscle of mice lacking the heart muscle isoform of the adenine nucleotide translocator. J. Biol. Chem. 1999, 274:14429-14433.
    • (1999) J. Biol. Chem. , vol.274 , pp. 14429-14433
    • Murdock, D.G.1    Boone, B.E.2    Esposito, L.A.3    Wallace, D.C.4
  • 38
    • 56349140990 scopus 로고    scopus 로고
    • Mouse models of oxidative phosphorylation defects: powerful tools to study the pathobiology of mitochondrial diseases
    • Torraco A., Diaz F., Vempati U.D., Moraes C.T. Mouse models of oxidative phosphorylation defects: powerful tools to study the pathobiology of mitochondrial diseases. Biochim. Biophys. Acta 2009, 1793:171-180.
    • (2009) Biochim. Biophys. Acta , vol.1793 , pp. 171-180
    • Torraco, A.1    Diaz, F.2    Vempati, U.D.3    Moraes, C.T.4
  • 40
    • 26444432919 scopus 로고    scopus 로고
    • Mitochondrial DNA polymerase γ is essential for mammalian embryogenesis
    • Hance N., Ekstrand M.I., Trifunovic A. Mitochondrial DNA polymerase γ is essential for mammalian embryogenesis. Hum. Mol. Genet. 2005, 14:1775-1783.
    • (2005) Hum. Mol. Genet. , vol.14 , pp. 1775-1783
    • Hance, N.1    Ekstrand, M.I.2    Trifunovic, A.3
  • 44
    • 0035169827 scopus 로고    scopus 로고
    • Mitochondrial DNA instability and peri-implantation lethality associated with targeted disruption of nuclear respiratory factor 1 in mice
    • Huo L., Scarpulla R.C. Mitochondrial DNA instability and peri-implantation lethality associated with targeted disruption of nuclear respiratory factor 1 in mice. Mol. Cell. Biol. 2001, 21:644-654.
    • (2001) Mol. Cell. Biol. , vol.21 , pp. 644-654
    • Huo, L.1    Scarpulla, R.C.2
  • 46
    • 0032880120 scopus 로고    scopus 로고
    • Targeted disruption of mouse yin yang 1 transcription factor results in peri-implantation lethality
    • Donohoe M.E., Zhang X., McGinnis L., Biggers J., Li E., Shi Y. Targeted disruption of mouse yin yang 1 transcription factor results in peri-implantation lethality. Mol. Cell. Biol. 1999, 19:7237-7244.
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 7237-7244
    • Donohoe, M.E.1    Zhang, X.2    McGinnis, L.3    Biggers, J.4    Li, E.5    Shi, Y.6
  • 47
    • 0242580188 scopus 로고    scopus 로고
    • Reduced fat mass in mice lacking orphan nuclear receptor estrogen-related receptor α
    • Luo J., Sladek R., Carrier J., Bader J., Richard D., Giguere V. Reduced fat mass in mice lacking orphan nuclear receptor estrogen-related receptor α. Mol. Biol. Cell 2003, 23:7947-7956.
    • (2003) Mol. Biol. Cell , vol.23 , pp. 7947-7956
    • Luo, J.1    Sladek, R.2    Carrier, J.3    Bader, J.4    Richard, D.5    Giguere, V.6
  • 48
    • 0028997684 scopus 로고
    • Targeted disruption of the alpha isoform of the peroxisome proliferator-activated receptor gene in mice results in abolishment of the pleiotropic effects of peroxisome proliferators
    • Lee S.S., Pineau T., Drago J., Lee E.J., Owens J.W., Kroetz D.L., Fernandez-Salguero P.M., Westphal H., Gonzalez F.J. Targeted disruption of the alpha isoform of the peroxisome proliferator-activated receptor gene in mice results in abolishment of the pleiotropic effects of peroxisome proliferators. Mol. Cell. Biol. 1995, 15:3012-3022.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 3012-3022
    • Lee, S.S.1    Pineau, T.2    Drago, J.3    Lee, E.J.4    Owens, J.W.5    Kroetz, D.L.6    Fernandez-Salguero, P.M.7    Westphal, H.8    Gonzalez, F.J.9
  • 50
    • 52249090234 scopus 로고    scopus 로고
    • ERRalpha: a metabolic function for the oldest orphan
    • Villena J.A., Kralli A. ERRalpha: a metabolic function for the oldest orphan. Trends Endocrinol. Metab. 2008, 19:269-276.
    • (2008) Trends Endocrinol. Metab. , vol.19 , pp. 269-276
    • Villena, J.A.1    Kralli, A.2
  • 51
    • 0027315650 scopus 로고
    • A null c-myc mutation causes lethality before 10.5days of gestation in homozygotes and reduced fertility in heterozygous female mice
    • Davis A.C., Wims M., Spotts G.D., Hann S.R., Bradley A. A null c-myc mutation causes lethality before 10.5days of gestation in homozygotes and reduced fertility in heterozygous female mice. Genes Dev. 1993, 7:671-682.
    • (1993) Genes Dev. , vol.7 , pp. 671-682
    • Davis, A.C.1    Wims, M.2    Spotts, G.D.3    Hann, S.R.4    Bradley, A.5
  • 52
    • 43549098260 scopus 로고    scopus 로고
    • The oncogene c-Myc coordinates regulation of metabolic networks to enable rapid cell cycle entry
    • Morrish F., Neretti N., Sedivy J.M., Hockenbery D.M. The oncogene c-Myc coordinates regulation of metabolic networks to enable rapid cell cycle entry. Cell Cycle 2008, 7:1054-1066.
    • (2008) Cell Cycle , vol.7 , pp. 1054-1066
    • Morrish, F.1    Neretti, N.2    Sedivy, J.M.3    Hockenbery, D.M.4
  • 53
    • 0032549811 scopus 로고    scopus 로고
    • A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis
    • Puigserver P., Wu Z., Park C.W., Graves R., Wright M., Spiegelman B.M. A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis. Cell 1998, 92:829-839.
    • (1998) Cell , vol.92 , pp. 829-839
    • Puigserver, P.1    Wu, Z.2    Park, C.W.3    Graves, R.4    Wright, M.5    Spiegelman, B.M.6
  • 54
    • 37349110355 scopus 로고    scopus 로고
    • Metabolic adaptations through the PGC-1 alpha and SIRT1 pathways
    • Rodgers J.T., Lerin C., Gerhart-Hines Z., Puigserver P. Metabolic adaptations through the PGC-1 alpha and SIRT1 pathways. FEBS Lett. 2008, 582:46-53.
    • (2008) FEBS Lett. , vol.582 , pp. 46-53
    • Rodgers, J.T.1    Lerin, C.2    Gerhart-Hines, Z.3    Puigserver, P.4
  • 55
    • 58149240182 scopus 로고    scopus 로고
    • Minireview: the PGC-1 coactivator networks: chromatin-remodeling and mitochondrial energy metabolism
    • Lin J.D. Minireview: the PGC-1 coactivator networks: chromatin-remodeling and mitochondrial energy metabolism. Mol. Endocrinol. 2009, 23:2-10.
    • (2009) Mol. Endocrinol. , vol.23 , pp. 2-10
    • Lin, J.D.1
  • 59
    • 33845948962 scopus 로고    scopus 로고
    • RIP140 expression is stimulated by estrogen-related receptor alpha during adipogenesis
    • Nichol D., Christian M., Steel J.H., White R., Parker M.G. RIP140 expression is stimulated by estrogen-related receptor alpha during adipogenesis. J. Biol. Chem. 2006, 281:32140-32147.
    • (2006) J. Biol. Chem. , vol.281 , pp. 32140-32147
    • Nichol, D.1    Christian, M.2    Steel, J.H.3    White, R.4    Parker, M.G.5
  • 62
    • 0033803048 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor γ coactivator-1 promotes cardiac mitochondrial biogenesis
    • Lehman J.J., Barger P.M., Kovacs A., Saffitz J.E., Medeiros D.M., Kelly D.P. Peroxisome proliferator-activated receptor γ coactivator-1 promotes cardiac mitochondrial biogenesis. J. Clin. Invest. 2000, 106:847-856.
    • (2000) J. Clin. Invest. , vol.106 , pp. 847-856
    • Lehman, J.J.1    Barger, P.M.2    Kovacs, A.3    Saffitz, J.E.4    Medeiros, D.M.5    Kelly, D.P.6
  • 63
    • 0033859843 scopus 로고    scopus 로고
    • The mechanism of action of thyroid hormones
    • Zhang J., Lazar M.A. The mechanism of action of thyroid hormones. Annu. Rev. Physiol. 2000, 62:439-466.
    • (2000) Annu. Rev. Physiol. , vol.62 , pp. 439-466
    • Zhang, J.1    Lazar, M.A.2
  • 64
    • 50049118173 scopus 로고    scopus 로고
    • Activation of the PPAR/PGC-1alpha pathway prevents a bioenergetic deficit and effectively improves a mitochondrial myopathy phenotype
    • Wenz T., Diaz F., Spiegelman B.M., Moraes C.T. Activation of the PPAR/PGC-1alpha pathway prevents a bioenergetic deficit and effectively improves a mitochondrial myopathy phenotype. Cell Metab. 2008, 8:249-256.
    • (2008) Cell Metab. , vol.8 , pp. 249-256
    • Wenz, T.1    Diaz, F.2    Spiegelman, B.M.3    Moraes, C.T.4
  • 66
    • 67650914230 scopus 로고    scopus 로고
    • AMPK in Health and Disease
    • Steinberg G.R., Kemp B.E. AMPK in Health and Disease. Physiol. Rev. 2009, 89:1025-1078.
    • (2009) Physiol. Rev. , vol.89 , pp. 1025-1078
    • Steinberg, G.R.1    Kemp, B.E.2
  • 67
    • 34547545892 scopus 로고    scopus 로고
    • AMP-activated protein kinase (AMPK) action in skeletal muscle via direct phosphorylation of PGC-1alpha
    • Jager S., Handschin C., St-Pierre J., Spiegelman B.M. AMP-activated protein kinase (AMPK) action in skeletal muscle via direct phosphorylation of PGC-1alpha. Proc. Natl. Acad. Sci. U. S. A. 2007, 104:12017-12022.
    • (2007) Proc. Natl. Acad. Sci. U. S. A. , vol.104 , pp. 12017-12022
    • Jager, S.1    Handschin, C.2    St-Pierre, J.3    Spiegelman, B.M.4
  • 70
    • 0037127204 scopus 로고    scopus 로고
    • PGC-1β: A novel PGC-1-related transcription coactivator associated with host cell factor
    • Lin J., Puigserver P., Donovan J., Tarr P., Spiegelman B.M. PGC-1β: A novel PGC-1-related transcription coactivator associated with host cell factor. J. Biol. Chem. 2002, 277:1645-1648.
    • (2002) J. Biol. Chem. , vol.277 , pp. 1645-1648
    • Lin, J.1    Puigserver, P.2    Donovan, J.3    Tarr, P.4    Spiegelman, B.M.5
  • 71
    • 0037134493 scopus 로고    scopus 로고
    • The PGC-1-related protein PERC is a selective coactivator of estrogen receptor α
    • Kressler D., Schreiber S.N., Knutti D., Kralli A. The PGC-1-related protein PERC is a selective coactivator of estrogen receptor α. J. Biol. Chem. 2002, 277:13918-13925.
    • (2002) J. Biol. Chem. , vol.277 , pp. 13918-13925
    • Kressler, D.1    Schreiber, S.N.2    Knutti, D.3    Kralli, A.4
  • 72
    • 0033638283 scopus 로고    scopus 로고
    • Direct coupling of transcription and mRNA processing through the thermogenic coactivator PGC-1
    • Monsalve M., Wu Z., Adelmant G., Puigserver P., Fan M., Spiegelman B.M. Direct coupling of transcription and mRNA processing through the thermogenic coactivator PGC-1. Mol. Cell 2000, 6:307-316.
    • (2000) Mol. Cell , vol.6 , pp. 307-316
    • Monsalve, M.1    Wu, Z.2    Adelmant, G.3    Puigserver, P.4    Fan, M.5    Spiegelman, B.M.6
  • 75
    • 0038036024 scopus 로고    scopus 로고
    • Bioenergetic analysis of peroxisome proliferator-activated receptor gamma coactivators 1α and 1β (PGC-1α and PGC-1β) in muscle cells
    • St Pierre J., Lin J., Krauss S., Tarr P.T., Yang R.J., Newgard C.B., Spiegelman B.M. Bioenergetic analysis of peroxisome proliferator-activated receptor gamma coactivators 1α and 1β (PGC-1α and PGC-1β) in muscle cells. J. Biol. Chem. 2003, 278:26597-26603.
    • (2003) J. Biol. Chem. , vol.278 , pp. 26597-26603
    • St Pierre, J.1    Lin, J.2    Krauss, S.3    Tarr, P.T.4    Yang, R.J.5    Newgard, C.B.6    Spiegelman, B.M.7
  • 76
    • 33646124709 scopus 로고    scopus 로고
    • Complementary action of the PGC-1 coactivators in mitochondrial biogenesis and brown fat differentiation
    • Uldry M., Yang W., St-Pierre J., Lin J., Seale P., Spiegelman B.M. Complementary action of the PGC-1 coactivators in mitochondrial biogenesis and brown fat differentiation. Cell Metab. 2006, 3:333-341.
    • (2006) Cell Metab. , vol.3 , pp. 333-341
    • Uldry, M.1    Yang, W.2    St-Pierre, J.3    Lin, J.4    Seale, P.5    Spiegelman, B.M.6
  • 78
    • 33845674997 scopus 로고    scopus 로고
    • The transcriptional coactivator PGC-1β drives the formation of oxidative type IIX fibers in skeletal muscle
    • Arany Z., Lebrasseur N., Morris C., Smith E., Yang W., Ma Y., Chin S., Spiegelman B.M. The transcriptional coactivator PGC-1β drives the formation of oxidative type IIX fibers in skeletal muscle. Cell Metab. 2007, 5:35-46.
    • (2007) Cell Metab. , vol.5 , pp. 35-46
    • Arany, Z.1    Lebrasseur, N.2    Morris, C.3    Smith, E.4    Yang, W.5    Ma, Y.6    Chin, S.7    Spiegelman, B.M.8
  • 79
    • 33644660537 scopus 로고    scopus 로고
    • PGC-1 coactivators: inducible regulators of energy metabolism in health and disease
    • Finck B.N., Kelly D.P. PGC-1 coactivators: inducible regulators of energy metabolism in health and disease. J. Clin. Invest. 2006, 116:615-622.
    • (2006) J. Clin. Invest. , vol.116 , pp. 615-622
    • Finck, B.N.1    Kelly, D.P.2
  • 83
    • 35648937073 scopus 로고    scopus 로고
    • Skeletal muscle fiber-type switching, exercise intolerance and myopathy in PGC-1alpha muscle-specific knockout animals
    • Handschin C., Chin S., Li P., Liu F., Maratos-Flier E., Lebrasseur N.K., Yan Z., Spiegelman B.M. Skeletal muscle fiber-type switching, exercise intolerance and myopathy in PGC-1alpha muscle-specific knockout animals. J. Biol. Chem. 2007, 282:30014-30021.
    • (2007) J. Biol. Chem. , vol.282 , pp. 30014-30021
    • Handschin, C.1    Chin, S.2    Li, P.3    Liu, F.4    Maratos-Flier, E.5    Lebrasseur, N.K.6    Yan, Z.7    Spiegelman, B.M.8
  • 85
    • 34247590356 scopus 로고    scopus 로고
    • PGC-1beta controls mitochondrial metabolism to modulate circadian activity, adaptive thermogenesis, and hepatic steatosis
    • Sonoda J., Mehl I.R., Chong L.W., Nofsinger R.R., Evans R.M. PGC-1beta controls mitochondrial metabolism to modulate circadian activity, adaptive thermogenesis, and hepatic steatosis. Proc. Natl. Acad. Sci. U. S. A. 2007, 104:5223-5228.
    • (2007) Proc. Natl. Acad. Sci. U. S. A. , vol.104 , pp. 5223-5228
    • Sonoda, J.1    Mehl, I.R.2    Chong, L.W.3    Nofsinger, R.R.4    Evans, R.M.5
  • 87
    • 47549114849 scopus 로고    scopus 로고
    • Transcriptional coactivators PGC-1alpha and PGC-lbeta control overlapping programs required for perinatal maturation of the heart
    • Lai L., Leone T.C., Zechner C., Schaeffer P.J., Kelly S.M., Flanagan D.P., Medeiros D.M., Kovacs A., Kelly D.P. Transcriptional coactivators PGC-1alpha and PGC-lbeta control overlapping programs required for perinatal maturation of the heart. Genes Dev. 2010, 22:1948-1961.
    • (2010) Genes Dev. , vol.22 , pp. 1948-1961
    • Lai, L.1    Leone, T.C.2    Zechner, C.3    Schaeffer, P.J.4    Kelly, S.M.5    Flanagan, D.P.6    Medeiros, D.M.7    Kovacs, A.8    Kelly, D.P.9
  • 88
  • 89
    • 0035016566 scopus 로고    scopus 로고
    • PGC-1-related coactivator, a novel, serum-inducible coactivator of nuclear respiratory factor 1-dependent transcription in mammalian cells
    • Andersson U., Scarpulla R.C. PGC-1-related coactivator, a novel, serum-inducible coactivator of nuclear respiratory factor 1-dependent transcription in mammalian cells. Mol. Cell. Biol. 2001, 21:3738-3749.
    • (2001) Mol. Cell. Biol. , vol.21 , pp. 3738-3749
    • Andersson, U.1    Scarpulla, R.C.2
  • 90
    • 45549103553 scopus 로고    scopus 로고
    • PGC-1-related Coactivator Complexes with HCF-1 and NRF-2β in Mediating NRF-2(GABP)-dependent Respiratory Gene Expression
    • Vercauteren K., Gleyzer N., Scarpulla R.C. PGC-1-related Coactivator Complexes with HCF-1 and NRF-2β in Mediating NRF-2(GABP)-dependent Respiratory Gene Expression. J. Biol. Chem. 2008, 283:12102-12111.
    • (2008) J. Biol. Chem. , vol.283 , pp. 12102-12111
    • Vercauteren, K.1    Gleyzer, N.2    Scarpulla, R.C.3
  • 91
    • 13444306450 scopus 로고    scopus 로고
    • Control of mitochondrial transcription specificity factors (TFB1M and TFB2M) by nuclear respiratory factors (NRF-1 and NRF-2) and PGC-1 family coactivators
    • Gleyzer N., Vercauteren K., Scarpulla R.C. Control of mitochondrial transcription specificity factors (TFB1M and TFB2M) by nuclear respiratory factors (NRF-1 and NRF-2) and PGC-1 family coactivators. Mol. Cell. Biol. 2005, 25:1354-1366.
    • (2005) Mol. Cell. Biol. , vol.25 , pp. 1354-1366
    • Gleyzer, N.1    Vercauteren, K.2    Scarpulla, R.C.3
  • 92
    • 0025769412 scopus 로고
    • Primary response genes induced by growth factors and tumor promoters
    • Herschman H.R. Primary response genes induced by growth factors and tumor promoters. Annu. Rev. Biochem. 1991, 60:281-319.
    • (1991) Annu. Rev. Biochem. , vol.60 , pp. 281-319
    • Herschman, H.R.1
  • 93
    • 0031972479 scopus 로고    scopus 로고
    • Serum- and polypeptide growth factor-inducible gene expression in mouse fibroblasts
    • Winkles J.A. Serum- and polypeptide growth factor-inducible gene expression in mouse fibroblasts. Prog. Nucleic Acid Res. Mol. Biol. 1998, 58:41-78.
    • (1998) Prog. Nucleic Acid Res. Mol. Biol. , vol.58 , pp. 41-78
    • Winkles, J.A.1
  • 94
    • 57649148823 scopus 로고    scopus 로고
    • Nuclear control of respiratory chain expression by nuclear respiratory factors and PGC-1-related coactivator
    • Scarpulla R.C. Nuclear control of respiratory chain expression by nuclear respiratory factors and PGC-1-related coactivator. Ann. N. Y. Acad. Sci. 2008, 1147:321-334.
    • (2008) Ann. N. Y. Acad. Sci. , vol.1147 , pp. 321-334
    • Scarpulla, R.C.1
  • 96
    • 0034651597 scopus 로고    scopus 로고
    • The novel coactivator C1 (HCF) coordinates multiprotein enhancer formation and mediates transcription activation by GABP
    • Vogel J.L., Kristie T.M. The novel coactivator C1 (HCF) coordinates multiprotein enhancer formation and mediates transcription activation by GABP. EMBO J. 2000, 19:683-690.
    • (2000) EMBO J. , vol.19 , pp. 683-690
    • Vogel, J.L.1    Kristie, T.M.2
  • 97
    • 0025167974 scopus 로고
    • A cellular factor binds to the herpes simplex virus type 1 transactivator Vmw65 and is required for Vmw65-dependent protein-DNA complex assembly with Oct-1
    • Xiao P., Capone J.P. A cellular factor binds to the herpes simplex virus type 1 transactivator Vmw65 and is required for Vmw65-dependent protein-DNA complex assembly with Oct-1. Mol. Cell. Biol. 1990, 10:4974-4977.
    • (1990) Mol. Cell. Biol. , vol.10 , pp. 4974-4977
    • Xiao, P.1    Capone, J.P.2
  • 99
    • 75149134754 scopus 로고    scopus 로고
    • Estrogen-related receptor alpha and PGC-1-related coactivator constitute a novel complex mediating the biogenesis of functional mitochondria
    • Mirebeau-Prunier D., Le P.S., Jacques C., Gueguen N., Poirier J., Malthiery Y., Savagner F. Estrogen-related receptor alpha and PGC-1-related coactivator constitute a novel complex mediating the biogenesis of functional mitochondria. FEBS J. 2010, 277:713-725.
    • (2010) FEBS J. , vol.277 , pp. 713-725
    • Mirebeau-Prunier, D.1    Le, P.S.2    Jacques, C.3    Gueguen, N.4    Poirier, J.5    Malthiery, Y.6    Savagner, F.7
  • 100
    • 0029874964 scopus 로고    scopus 로고
    • Use of fibroblast and lymphoblast cultures for detection of respiratory chain defects
    • Robinson B.H. Use of fibroblast and lymphoblast cultures for detection of respiratory chain defects. Methods Enzymol. 1996, 264:454-464.
    • (1996) Methods Enzymol. , vol.264 , pp. 454-464
    • Robinson, B.H.1
  • 101
    • 59049089797 scopus 로고    scopus 로고
    • Short hairpin RNA-mediated silencing of PRC (PGC-1-related coactivator) results in a severe respiratory chain deficiency associated with the proliferation of aberrant mitochondria
    • Vercauteren K., Gleyzer N., Scarpulla R.C. Short hairpin RNA-mediated silencing of PRC (PGC-1-related coactivator) results in a severe respiratory chain deficiency associated with the proliferation of aberrant mitochondria. J. Biol. Chem. 2009, 284:2307-2319.
    • (2009) J. Biol. Chem. , vol.284 , pp. 2307-2319
    • Vercauteren, K.1    Gleyzer, N.2    Scarpulla, R.C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.