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Volumn 112, Issue 6, 2010, Pages 1415-1430

Naturally occurring phytochemicals for the prevention of Alzheimer's disease

Author keywords

( ) epigallocatechin 3 gallate; Alzheimer's disease; Amyloid ; Curcumin; Phytochemicals; Resveratrol

Indexed keywords

ACUTE PHASE PROTEIN; ALPHA TOCOPHEROL; AMYLOID BETA PROTEIN; ASCORBIC ACID; CATECHIN; CHEMOKINE; COMPLEMENT; CURCUMIN; CYCLOOXYGENASE 2; CYTOKINE; DONEPEZIL; EPIGALLOCATECHIN GALLATE; FREE RADICAL; GALANTAMINE; INDUCIBLE NITRIC OXIDE SYNTHASE; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; MEMANTINE; NITRIC OXIDE; PLANT MEDICINAL PRODUCT; POLYPHENOL; PROSTAGLANDIN; PROTEIN S 100; RESVERATROL; RIVASTIGMINE; TACRINE;

EID: 77349084360     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2009.06562.x     Document Type: Review
Times cited : (298)

References (176)
  • 1
    • 0037108115 scopus 로고    scopus 로고
    • Green tea polyphenol epigallocatechin-3-gallate inhibits the IL-1 beta-induced activity and expression of cyclooxygenase-2 and nitric oxide synthase-2 in human chondrocytes
    • Ahmed S., Rahman A., Hasnain A., Lalonde M., Goldberg V. M. Haqqi T. M. (2002) Green tea polyphenol epigallocatechin-3-gallate inhibits the IL-1 beta-induced activity and expression of cyclooxygenase-2 and nitric oxide synthase-2 in human chondrocytes. Free Radic. Biol. Med. 33, 1097 1105.
    • (2002) Free Radic. Biol. Med. , vol.33 , pp. 1097-1105
    • Ahmed, S.1    Rahman, A.2    Hasnain, A.3    Lalonde, M.4    Goldberg, V.M.5    Haqqi, T.M.6
  • 2
    • 0034576747 scopus 로고    scopus 로고
    • Anti-inflammatory therapy for Alzheimer's disease: Implications of the prednisone trial
    • Aisen P. S. (2000) Anti-inflammatory therapy for Alzheimer's disease: implications of the prednisone trial. Acta Neurol. Scand. Suppl. 176, 85 89.
    • (2000) Acta Neurol. Scand. Suppl. , vol.176 , pp. 85-89
    • Aisen, P.S.1
  • 3
    • 0037046179 scopus 로고    scopus 로고
    • Randomized pilot study of nimesulide treatment in Alzheimer's disease
    • Aisen P. S., Schmeidler J. Pasinetti G. M. (2002) Randomized pilot study of nimesulide treatment in Alzheimer's disease. Neurology 58, 1050 1054.
    • (2002) Neurology , vol.58 , pp. 1050-1054
    • Aisen, P.S.1    Schmeidler, J.2    Pasinetti, G.M.3
  • 5
    • 0034612175 scopus 로고    scopus 로고
    • Inflammation and Alzheimer's disease
    • Akiyama H., Barger S., Barnum S. et al. (2000) Inflammation and Alzheimer's disease. Neurobiol. Aging 21, 383 421.
    • (2000) Neurobiol. Aging , vol.21 , pp. 383-421
    • Akiyama, H.1    Barger, S.2    Barnum, S.3
  • 8
    • 0033835996 scopus 로고    scopus 로고
    • Peripherally administered antibodies against amyloid beta-peptide enter the central nervous system and reduce pathology in a mouse model of Alzheimer disease
    • Bard F., Cannon C., Barbour R. et al. (2000) Peripherally administered antibodies against amyloid beta-peptide enter the central nervous system and reduce pathology in a mouse model of Alzheimer disease. Nat. Med. 6, 916 919.
    • (2000) Nat. Med. , vol.6 , pp. 916-919
    • Bard, F.1    Cannon, C.2    Barbour, R.3
  • 9
    • 33644949188 scopus 로고    scopus 로고
    • Neuroprotective effects of green and black teas and their catechin gallate esters against beta-amyloid-induced toxicity
    • Bastianetto S., Yao Z. X., Papadopoulos V. Quirion R. (2006) Neuroprotective effects of green and black teas and their catechin gallate esters against beta-amyloid-induced toxicity. Eur. J. Neurosci. 23, 55 64.
    • (2006) Eur. J. Neurosci. , vol.23 , pp. 55-64
    • Bastianetto, S.1    Yao, Z.X.2    Papadopoulos, V.3    Quirion, R.4
  • 10
    • 4644275696 scopus 로고    scopus 로고
    • Curcumin interaction with copper and iron suggests one possible mechanism of action in Alzheimer's disease animal models
    • Baum L. Ng A. (2004) Curcumin interaction with copper and iron suggests one possible mechanism of action in Alzheimer's disease animal models. J. Alzheimers Dis. 6, 367 377.
    • (2004) J. Alzheimers Dis. , vol.6 , pp. 367-377
    • Baum, L.1    Ng, A.2
  • 11
    • 0028233494 scopus 로고
    • Hydrogen peroxide mediates amyloid beta protein toxicity
    • Behl C., Davis J. B., Lesley R. Schubert D. (1994) Hydrogen peroxide mediates amyloid beta protein toxicity. Cell 77, 817 827.
    • (1994) Cell , vol.77 , pp. 817-827
    • Behl, C.1    Davis, J.B.2    Lesley, R.3    Schubert, D.4
  • 12
    • 30744435048 scopus 로고    scopus 로고
    • Curcumin, an atoxic antioxidant and natural NFkappaB, cyclooxygenase-2, lipooxygenase, and inducible nitric oxide synthase inhibitor: A shield against acute and chronic diseases
    • Bengmark S. (2006) Curcumin, an atoxic antioxidant and natural NFkappaB, cyclooxygenase-2, lipooxygenase, and inducible nitric oxide synthase inhibitor: a shield against acute and chronic diseases. J. Parenter. Enteral Nutr. 30, 45 51.
    • (2006) J. Parenter. Enteral Nutr. , vol.30 , pp. 45-51
    • Bengmark, S.1
  • 14
    • 0032621790 scopus 로고    scopus 로고
    • TNFalpha plus IFNgamma induce the production of Alzheimer beta-amyloid peptides and decrease the secretion of APPs
    • Blasko I., Marx F., Steiner E., Hartmann T. Grubeck-Loebenstein B. (1999) TNFalpha plus IFNgamma induce the production of Alzheimer beta-amyloid peptides and decrease the secretion of APPs. FASEB J. 13, 63 68.
    • (1999) FASEB J. , vol.13 , pp. 63-68
    • Blasko, I.1    Marx, F.2    Steiner, E.3    Hartmann, T.4    Grubeck-Loebenstein, B.5
  • 16
    • 77049122576 scopus 로고    scopus 로고
    • Protective effects of resveratrol and quercetin against MPP(+)-induced oxidative stress act by modulating markers of apoptotic death in dopaminergic neurons
    • Bournival J., Quessy P. Martinoli M. G. (2009) Protective effects of resveratrol and quercetin against MPP(+)-induced oxidative stress act by modulating markers of apoptotic death in dopaminergic neurons. Cell. Mol. Neurobiol. 29, 1169 1180.
    • (2009) Cell. Mol. Neurobiol. , vol.29 , pp. 1169-1180
    • Bournival, J.1    Quessy, P.2    Martinoli, M.G.3
  • 17
    • 0028289083 scopus 로고
    • Inverse association of anti-inflammatory treatments and Alzheimer's disease: Initial results of a co-twin control study
    • Breitner J. C., Gau B. A., Welsh K. A., Plassman B. L., McDonald W. M., Helms M. J. Anthony J. C. (1994) Inverse association of anti-inflammatory treatments and Alzheimer's disease: initial results of a co-twin control study. Neurology 44, 227 232.
    • (1994) Neurology , vol.44 , pp. 227-232
    • Breitner, J.C.1    Gau, B.A.2    Welsh, K.A.3    Plassman, B.L.4    McDonald, W.M.5    Helms, M.J.6    Anthony, J.C.7
  • 18
    • 34250844410 scopus 로고    scopus 로고
    • Biological stress response terminology: Integrating the concepts of adaptive response and preconditioning stress within a hormetic dose-response framework
    • Calabrese E. J., Bachmann K. A., Bailer A. J. et al. (2007a) Biological stress response terminology: Integrating the concepts of adaptive response and preconditioning stress within a hormetic dose-response framework. Toxicol. Appl. Pharmacol. 222, 122 128.
    • (2007) Toxicol. Appl. Pharmacol. , vol.222 , pp. 122-128
    • Calabrese, E.J.1    Bachmann, K.A.2    Bailer, A.J.3
  • 20
    • 56449129616 scopus 로고    scopus 로고
    • Cellular stress response: A novel target for chemoprevention and nutritional neuroprotection in aging, neurodegenerative disorders and longevity
    • Calabrese V., Cornelius C., Mancuso C. et al. (2008) Cellular stress response: a novel target for chemoprevention and nutritional neuroprotection in aging, neurodegenerative disorders and longevity. Neurochem. Res. 33, 2444 2471.
    • (2008) Neurochem. Res. , vol.33 , pp. 2444-2471
    • Calabrese, V.1    Cornelius, C.2    Mancuso, C.3
  • 23
    • 36849092504 scopus 로고    scopus 로고
    • Resveratrol potently reduces prostaglandin E2 production and free radical formation in lipopolysaccharide-activated primary rat microglia
    • Candelario-Jalil E., de Oliveira A. C., Graf S., Bhatia H. S., Hull M., Munoz E. Fiebich B. L. (2007) Resveratrol potently reduces prostaglandin E2 production and free radical formation in lipopolysaccharide-activated primary rat microglia. J. Neuroinflammation 4, 25.
    • (2007) J. Neuroinflammation , vol.4 , pp. 25
    • Candelario-Jalil, E.1    De Oliveira, A.C.2    Graf, S.3    Bhatia, H.S.4    Hull, M.5    Munoz, E.6    Fiebich, B.L.7
  • 24
    • 1942484416 scopus 로고    scopus 로고
    • Potent induction of cellular antioxidants and phase 2 enzymes by resveratrol in cardiomyocytes: Protection against oxidative and electrophilic injury
    • Cao Z. Li Y. (2004) Potent induction of cellular antioxidants and phase 2 enzymes by resveratrol in cardiomyocytes: protection against oxidative and electrophilic injury. Eur. J. Pharmacol. 489, 39 48.
    • (2004) Eur. J. Pharmacol. , vol.489 , pp. 39-48
    • Cao, Z.1    Li, Y.2
  • 25
    • 0034573074 scopus 로고    scopus 로고
    • Activation of antioxidant-response element (ARE), mitogen-activated protein kinases (MAPKs) and caspases by major green tea polyphenol components during cell survival and death
    • Chen C., Yu R., Owuor E. D. Kong A. N. (2000) Activation of antioxidant-response element (ARE), mitogen-activated protein kinases (MAPKs) and caspases by major green tea polyphenol components during cell survival and death. Arch. Pharm. Res. 23, 605 612.
    • (2000) Arch. Pharm. Res. , vol.23 , pp. 605-612
    • Chen, C.1    Yu, R.2    Owuor, E.D.3    Kong, A.N.4
  • 26
    • 33745056543 scopus 로고    scopus 로고
    • Curcumin protects PC12 cells against 1-methyl-4-phenylpyridinium ion-induced apoptosis by bcl-2-mitochondria-ROS-iNOS pathway
    • Chen J., Tang X. Q., Zhi J. L., Cui Y., Yu H. M., Tang E. H., Sun S. N., Feng J. Q. Chen P. X. (2006) Curcumin protects PC12 cells against 1-methyl-4-phenylpyridinium ion-induced apoptosis by bcl-2-mitochondria-ROS-iNOS pathway. Apoptosis 11, 943 953.
    • (2006) Apoptosis , vol.11 , pp. 943-953
    • Chen, J.1    Tang, X.Q.2    Zhi, J.L.3    Cui, Y.4    Yu, H.M.5    Tang, E.H.6    Sun, S.N.7    Feng, J.Q.8    Chen, P.X.9
  • 27
    • 0035930961 scopus 로고    scopus 로고
    • The green tea polyphenol (-)-epigallocatechin gallate attenuates beta-amyloid-induced neurotoxicity in cultured hippocampal neurons
    • Choi Y. T., Jung C. H., Lee S. R., Bae J. H., Baek W. K., Suh M. H., Park J., Park C. W. Suh S. I. (2001) The green tea polyphenol (-)-epigallocatechin gallate attenuates beta-amyloid-induced neurotoxicity in cultured hippocampal neurons. Life Sci. 70, 603 614.
    • (2001) Life Sci. , vol.70 , pp. 603-614
    • Choi, Y.T.1    Jung, C.H.2    Lee, S.R.3    Bae, J.H.4    Baek, W.K.5    Suh, M.H.6    Park, J.7    Park, C.W.8    Suh, S.I.9
  • 28
    • 0036746177 scopus 로고    scopus 로고
    • Prevention of nitric oxide-mediated 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine-induced Parkinson's disease in mice by tea phenolic epigallocatechin 3-gallate
    • Choi J. Y., Park C. S., Kim D. J., Cho M. H., Jin B. K., Pie J. E. Chung W. G. (2002) Prevention of nitric oxide-mediated 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine-induced Parkinson's disease in mice by tea phenolic epigallocatechin 3-gallate. Neurotoxicology 23, 367 374.
    • (2002) Neurotoxicology , vol.23 , pp. 367-374
    • Choi, J.Y.1    Park, C.S.2    Kim, D.J.3    Cho, M.H.4    Jin, B.K.5    Pie, J.E.6    Chung, W.G.7
  • 29
    • 0035866060 scopus 로고    scopus 로고
    • Beta-amyloid stimulation of microglia and monocytes results in TNFalpha-dependent expression of inducible nitric oxide synthase and neuronal apoptosis
    • Combs C. K., Karlo J. C., Kao S. C. Landreth G. E. (2001) Beta-amyloid stimulation of microglia and monocytes results in TNFalpha-dependent expression of inducible nitric oxide synthase and neuronal apoptosis. J. Neurosci. 21, 1179 1188.
    • (2001) J. Neurosci. , vol.21 , pp. 1179-1188
    • Combs, C.K.1    Karlo, J.C.2    Kao, S.C.3    Landreth, G.E.4
  • 31
    • 62249110887 scopus 로고    scopus 로고
    • Resveratrol pretreatment protects rat brain from cerebral ischemic damage via a sirtuin 1 - Uncoupling protein 2 pathway
    • Della-Morte D., Dave K. R., Defazio R. A., Bao Y. C., Raval A. P. Perez-Pinzon M. A. (2009) Resveratrol pretreatment protects rat brain from cerebral ischemic damage via a sirtuin 1 - uncoupling protein 2 pathway. Neuroscience 159, 993 1002.
    • (2009) Neuroscience , vol.159 , pp. 993-1002
    • Della-Morte, D.1    Dave, K.R.2    Defazio, R.A.3    Bao, Y.C.4    Raval, A.P.5    Perez-Pinzon, M.A.6
  • 32
    • 0035902619 scopus 로고    scopus 로고
    • Peripheral anti-A beta antibody alters CNS and plasma A beta clearance and decreases brain A beta burden in a mouse model of Alzheimer's disease
    • DeMattos R. B., Bales K. R., Cummins D. J., Dodart J. C., Paul S. M. Holtzman D. M. (2001) Peripheral anti-A beta antibody alters CNS and plasma A beta clearance and decreases brain A beta burden in a mouse model of Alzheimer's disease. Proc. Natl Acad. Sci. USA 98, 8850 8855.
    • (2001) Proc. Natl Acad. Sci. USA , vol.98 , pp. 8850-8855
    • Demattos, R.B.1    Bales, K.R.2    Cummins, D.J.3    Dodart, J.C.4    Paul, S.M.5    Holtzman, D.M.6
  • 33
    • 33847369469 scopus 로고    scopus 로고
    • The high-affinity HSP90-CHIP complex recognizes and selectively degrades phosphorylated tau client proteins
    • Dickey C. A., Kamal A., Lundgren K. et al. (2007) The high-affinity HSP90-CHIP complex recognizes and selectively degrades phosphorylated tau client proteins. J. Clin. Invest. 117, 648 658.
    • (2007) J. Clin. Invest. , vol.117 , pp. 648-658
    • Dickey, C.A.1    Kamal, A.2    Lundgren, K.3
  • 34
    • 0036240395 scopus 로고    scopus 로고
    • Immunization reverses memory deficits without reducing brain Abeta burden in Alzheimer's disease model
    • Dodart J. C., Bales K. R., Gannon K. S. et al. (2002) Immunization reverses memory deficits without reducing brain Abeta burden in Alzheimer's disease model. Nat. Neurosci. 5, 452 457.
    • (2002) Nat. Neurosci. , vol.5 , pp. 452-457
    • Dodart, J.C.1    Bales, K.R.2    Gannon, K.S.3
  • 35
    • 34447505041 scopus 로고    scopus 로고
    • Berry phytochemicals, genomic stability and cancer: Evidence for chemoprotection at several stages in the carcinogenic process
    • Duthie S. J. (2007) Berry phytochemicals, genomic stability and cancer: evidence for chemoprotection at several stages in the carcinogenic process. Mol. Nutr. Food Res. 51, 665 674.
    • (2007) Mol. Nutr. Food Res. , vol.51 , pp. 665-674
    • Duthie, S.J.1
  • 36
    • 33748744375 scopus 로고    scopus 로고
    • Green tea (-)-epigallocatechin-gallate modulates early events in huntingtin misfolding and reduces toxicity in Huntington's disease models
    • Ehrnhoefer D. E., Duennwald M., Markovic P. et al. (2006) Green tea (-)-epigallocatechin-gallate modulates early events in huntingtin misfolding and reduces toxicity in Huntington's disease models. Hum. Mol. Genet. 15, 2743 2751.
    • (2006) Hum. Mol. Genet. , vol.15 , pp. 2743-2751
    • Ehrnhoefer, D.E.1    Duennwald, M.2    Markovic, P.3
  • 38
    • 39149106003 scopus 로고    scopus 로고
    • Curcumin attenuates dimethylnitrosamine-induced liver injury in rats through Nrf2-mediated induction of heme oxygenase-1
    • Farombi E. O., Shrotriya S., Na H. K., Kim S. H. Surh Y. J. (2008) Curcumin attenuates dimethylnitrosamine-induced liver injury in rats through Nrf2-mediated induction of heme oxygenase-1. Food Chem. Toxicol. 46, 1279 1287.
    • (2008) Food Chem. Toxicol. , vol.46 , pp. 1279-1287
    • Farombi, E.O.1    Shrotriya, S.2    Na, H.K.3    Kim, S.H.4    Surh, Y.J.5
  • 39
    • 1342332161 scopus 로고    scopus 로고
    • The LPS receptor (CD14) links innate immunity with Alzheimer's disease
    • Fassbender K., Walter S., Kuhl S. et al. (2004) The LPS receptor (CD14) links innate immunity with Alzheimer's disease. FASEB J. 18, 203 205.
    • (2004) FASEB J. , vol.18 , pp. 203-205
    • Fassbender, K.1    Walter, S.2    Kuhl, S.3
  • 40
    • 1042265187 scopus 로고    scopus 로고
    • Neuropathology and pathogenesis of encephalitis following amyloid-beta immunization in Alzheimer's disease
    • Ferrer I., Boada Rovira M., Sanchez Guerra M. L., Rey M. J. Costa-Jussa F. (2004) Neuropathology and pathogenesis of encephalitis following amyloid-beta immunization in Alzheimer's disease. Brain Pathol. 14, 11 20.
    • (2004) Brain Pathol. , vol.14 , pp. 11-20
    • Ferrer, I.1    Boada Rovira, M.2    Sanchez Guerra, M.L.3    Rey, M.J.4    Costa-Jussa, F.5
  • 41
    • 3242766671 scopus 로고    scopus 로고
    • Absence of C1q leads to less neuropathology in transgenic mouse models of Alzheimer's disease
    • Fonseca M. I., Zhou J., Botto M. Tenner A. J. (2004) Absence of C1q leads to less neuropathology in transgenic mouse models of Alzheimer's disease. J. Neurosci. 24, 6457 6465.
    • (2004) J. Neurosci. , vol.24 , pp. 6457-6465
    • Fonseca, M.I.1    Zhou, J.2    Botto, M.3    Tenner, A.J.4
  • 43
    • 0035686083 scopus 로고    scopus 로고
    • Phenolic anti-inflammatory antioxidant reversal of Abeta-induced cognitive deficits and neuropathology
    • Frautschy S. A., Hu W., Kim P., Miller S. A., Chu T., Harris-White M. E. Cole G. M. (2001) Phenolic anti-inflammatory antioxidant reversal of Abeta-induced cognitive deficits and neuropathology. Neurobiol. Aging 22, 993 1005.
    • (2001) Neurobiol. Aging , vol.22 , pp. 993-1005
    • Frautschy, S.A.1    Hu, W.2    Kim, P.3    Miller, S.A.4    Chu, T.5    Harris-White, M.E.6    Cole, G.M.7
  • 44
    • 20144365700 scopus 로고    scopus 로고
    • Nuclear trapping of the forkhead transcription factor FoxO1 via Sirt-dependent deacetylation promotes expression of glucogenetic genes
    • Frescas D., Valenti L. Accili D. (2005) Nuclear trapping of the forkhead transcription factor FoxO1 via Sirt-dependent deacetylation promotes expression of glucogenetic genes. J. Biol. Chem. 280, 20589 20595.
    • (2005) J. Biol. Chem. , vol.280 , pp. 20589-20595
    • Frescas, D.1    Valenti, L.2    Accili, D.3
  • 46
    • 34547451145 scopus 로고    scopus 로고
    • Curcumin labels amyloid pathology in vivo, disrupts existing plaques, and partially restores distorted neurites in an Alzheimer mouse model
    • Garcia-Alloza M., Borrelli L. A., Rozkalne A., Hyman B. T. Bacskai B. J. (2007) Curcumin labels amyloid pathology in vivo, disrupts existing plaques, and partially restores distorted neurites in an Alzheimer mouse model. J. Neurochem. 102, 1095 1104.
    • (2007) J. Neurochem. , vol.102 , pp. 1095-1104
    • Garcia-Alloza, M.1    Borrelli, L.A.2    Rozkalne, A.3    Hyman, B.T.4    Bacskai, B.J.5
  • 48
    • 20944448555 scopus 로고    scopus 로고
    • Clinical effects of Abeta immunization (AN1792) in patients with AD in an interrupted trial
    • Gilman S., Koller M., Black R. S. et al. (2005) Clinical effects of Abeta immunization (AN1792) in patients with AD in an interrupted trial. Neurology 64, 1553 1562.
    • (2005) Neurology , vol.64 , pp. 1553-1562
    • Gilman, S.1    Koller, M.2    Black, R.S.3
  • 49
    • 9744229172 scopus 로고    scopus 로고
    • Curcumin, the active constituent of turmeric, inhibits amyloid peptide-induced cytochemokine gene expression and CCR5-mediated chemotaxis of THP-1 monocytes by modulating early growth response-1 transcription factor
    • Giri R. K., Rajagopal V. Kalra V. K. (2004) Curcumin, the active constituent of turmeric, inhibits amyloid peptide-induced cytochemokine gene expression and CCR5-mediated chemotaxis of THP-1 monocytes by modulating early growth response-1 transcription factor. J. Neurochem. 91, 1199 1210.
    • (2004) J. Neurochem. , vol.91 , pp. 1199-1210
    • Giri, R.K.1    Rajagopal, V.2    Kalra, V.K.3
  • 50
    • 0034814629 scopus 로고    scopus 로고
    • Nutrition and cognitive impairment in the elderly
    • Gonzalez-Gross M., Marcos A. Pietrzik K. (2001) Nutrition and cognitive impairment in the elderly. Br. J. Nutr. 86, 313 321.
    • (2001) Br. J. Nutr. , vol.86 , pp. 313-321
    • Gonzalez-Gross, M.1    Marcos, A.2    Pietrzik, K.3
  • 51
    • 0026573467 scopus 로고
    • Selective accumulation of aluminum and iron in the neurofibrillary tangles of Alzheimer's disease: A laser microprobe (LAMMA) study
    • Good P. F., Perl D. P., Bierer L. M. Schmeidler J. (1992) Selective accumulation of aluminum and iron in the neurofibrillary tangles of Alzheimer's disease: a laser microprobe (LAMMA) study. Ann. Neurol. 31, 286 292.
    • (1992) Ann. Neurol. , vol.31 , pp. 286-292
    • Good, P.F.1    Perl, D.P.2    Bierer, L.M.3    Schmeidler, J.4
  • 52
    • 0037101616 scopus 로고    scopus 로고
    • Inflammation-dependent cerebral deposition of serum amyloid a protein in a mouse model of amyloidosis
    • Guo J. T., Yu J., Grass D., de Beer F. C. Kindy M. S. (2002) Inflammation-dependent cerebral deposition of serum amyloid a protein in a mouse model of amyloidosis. J. Neurosci. 22, 5900 5909.
    • (2002) J. Neurosci. , vol.22 , pp. 5900-5909
    • Guo, J.T.1    Yu, J.2    Grass, D.3    De Beer, F.C.4    Kindy, M.S.5
  • 53
    • 0038823692 scopus 로고    scopus 로고
    • Epigallocatechin gallate, a constituent of green tea, suppresses cytokine-induced pancreatic beta-cell damage
    • Han M. K. (2003) Epigallocatechin gallate, a constituent of green tea, suppresses cytokine-induced pancreatic beta-cell damage. Exp. Mol. Med. 35, 136 139.
    • (2003) Exp. Mol. Med. , vol.35 , pp. 136-139
    • Han, M.K.1
  • 54
    • 1942472491 scopus 로고    scopus 로고
    • Neuroprotective effects of resveratrol against beta-amyloid-induced neurotoxicity in rat hippocampal neurons: Involvement of protein kinase C
    • Han Y. S., Zheng W. H., Bastianetto S., Chabot J. G. Quirion R. (2004) Neuroprotective effects of resveratrol against beta-amyloid-induced neurotoxicity in rat hippocampal neurons: involvement of protein kinase C. Br. J. Pharmacol. 141, 997 1005.
    • (2004) Br. J. Pharmacol. , vol.141 , pp. 997-1005
    • Han, Y.S.1    Zheng, W.H.2    Bastianetto, S.3    Chabot, J.G.4    Quirion, R.5
  • 55
    • 44249109772 scopus 로고    scopus 로고
    • Green tea catechins prevent cognitive deficits caused by Abeta1-40 in rats
    • Haque A. M., Hashimoto M., Katakura M., Hara Y. Shido O. (2008) Green tea catechins prevent cognitive deficits caused by Abeta1-40 in rats. J. Nutr. Biochem. 19, 619 626.
    • (2008) J. Nutr. Biochem. , vol.19 , pp. 619-626
    • Haque, A.M.1    Hashimoto, M.2    Katakura, M.3    Hara, Y.4    Shido, O.5
  • 56
    • 0026597063 scopus 로고
    • Alzheimer's disease: The amyloid cascade hypothesis
    • Hardy J. A. Higgins G. A. (1992) Alzheimer's disease: the amyloid cascade hypothesis. Science 256, 184 185.
    • (1992) Science , vol.256 , pp. 184-185
    • Hardy, J.A.1    Higgins, G.A.2
  • 57
    • 33847613885 scopus 로고    scopus 로고
    • Inflammatory processes in Alzheimer's disease
    • Heneka M. T. O'Banion M. K. (2007) Inflammatory processes in Alzheimer's disease. J. Neuroimmunol. 184, 69 91.
    • (2007) J. Neuroimmunol. , vol.184 , pp. 69-91
    • Heneka, M.T.1    O'Banion, M.K.2
  • 58
    • 0028985209 scopus 로고
    • Amyloid beta-peptide spin trapping. II: Evidence for decomposition of the PBN spin adduct
    • Hensley K., Aksenova M., Carney J. M., Harris M. Butterfield D. A. (1995) Amyloid beta-peptide spin trapping. II: Evidence for decomposition of the PBN spin adduct. Neuroreport 6, 493 496.
    • (1995) Neuroreport , vol.6 , pp. 493-496
    • Hensley, K.1    Aksenova, M.2    Carney, J.M.3    Harris, M.4    Butterfield, D.A.5
  • 59
    • 0038100154 scopus 로고    scopus 로고
    • Antibodies against beta-amyloid slow cognitive decline in Alzheimer's disease
    • Hock C., Konietzko U., Streffer J. R. et al. (2003) Antibodies against beta-amyloid slow cognitive decline in Alzheimer's disease. Neuron 38, 547 554.
    • (2003) Neuron , vol.38 , pp. 547-554
    • Hock, C.1    Konietzko, U.2    Streffer, J.R.3
  • 60
    • 0037591210 scopus 로고    scopus 로고
    • Animal self-medication and ethno-medicine: Exploration and exploitation of the medicinal properties of plants
    • Huffman M. A. (2003) Animal self-medication and ethno-medicine: exploration and exploitation of the medicinal properties of plants. Proc. Nutr. Soc. 62, 371 381.
    • (2003) Proc. Nutr. Soc. , vol.62 , pp. 371-381
    • Huffman, M.A.1
  • 61
    • 0035865819 scopus 로고    scopus 로고
    • Flavonoids protect neuronal cells from oxidative stress by three distinct mechanisms
    • Ishige K., Schubert D. Sagara Y. (2001) Flavonoids protect neuronal cells from oxidative stress by three distinct mechanisms. Free Radic. Biol. Med. 30, 433 446.
    • (2001) Free Radic. Biol. Med. , vol.30 , pp. 433-446
    • Ishige, K.1    Schubert, D.2    Sagara, Y.3
  • 62
    • 67650705731 scopus 로고    scopus 로고
    • Amelioration of cognitive deficits and neurodegeneration by curcumin in rat model of sporadic dementia of Alzheimer's type (SDAT)
    • Ishrat T., Hoda M. N., Khan M. B., Yousuf S., Ahmad M., Khan M. M., Ahmad A. Islam F. (2009) Amelioration of cognitive deficits and neurodegeneration by curcumin in rat model of sporadic dementia of Alzheimer's type (SDAT). Eur. Neuropsychopharmacol. 19, 636 647.
    • (2009) Eur. Neuropsychopharmacol. , vol.19 , pp. 636-647
    • Ishrat, T.1    Hoda, M.N.2    Khan, M.B.3    Yousuf, S.4    Ahmad, M.5    Khan, M.M.6    Ahmad, A.7    Islam, F.8
  • 63
    • 0037446328 scopus 로고    scopus 로고
    • Protective effect of resveratrol on beta-amyloid-induced oxidative PC12 cell death
    • Jang J. H. Surh Y. J. (2003) Protective effect of resveratrol on beta-amyloid-induced oxidative PC12 cell death. Free Radic. Biol. Med. 34, 1100 1110.
    • (2003) Free Radic. Biol. Med. , vol.34 , pp. 1100-1110
    • Jang, J.H.1    Surh, Y.J.2
  • 64
    • 0034700471 scopus 로고    scopus 로고
    • A beta peptide immunization reduces behavioural impairment and plaques in a model of Alzheimer's disease
    • Janus C., Pearson J., McLaurin J. et al. (2000) A beta peptide immunization reduces behavioural impairment and plaques in a model of Alzheimer's disease. Nature 408, 979 982.
    • (2000) Nature , vol.408 , pp. 979-982
    • Janus, C.1    Pearson, J.2    McLaurin, J.3
  • 65
    • 0242285619 scopus 로고    scopus 로고
    • Green tea catechins as a BACE1 (beta-secretase) inhibitor
    • Jeon S. Y., Bae K., Seong Y. H. Song K. S. (2003) Green tea catechins as a BACE1 (beta-secretase) inhibitor. Bioorg. Med. Chem. Lett. 13, 3905 3908.
    • (2003) Bioorg. Med. Chem. Lett. , vol.13 , pp. 3905-3908
    • Jeon, S.Y.1    Bae, K.2    Seong, Y.H.3    Song, K.S.4
  • 66
    • 56149119401 scopus 로고    scopus 로고
    • Neuroprotective effect of resveratrol on 6-OHDA-induced Parkinson's disease in rats
    • Jin F., Wu Q., Lu Y. F., Gong Q. H. Shi J. S. (2008) Neuroprotective effect of resveratrol on 6-OHDA-induced Parkinson's disease in rats. Eur. J. Pharmacol. 600, 78 82.
    • (2008) Eur. J. Pharmacol. , vol.600 , pp. 78-82
    • Jin, F.1    Wu, Q.2    Lu, Y.F.3    Gong, Q.H.4    Shi, J.S.5
  • 67
    • 0028990941 scopus 로고
    • APOE*4-associated Alzheimer's disease risk is modified by alpha 1-antichymotrypsin polymorphism
    • Kamboh M. I., Sanghera D. K., Ferrell R. E. DeKosky S. T. (1995) APOE*4-associated Alzheimer's disease risk is modified by alpha 1-antichymotrypsin polymorphism. Nat. Genet. 10, 486 488.
    • (1995) Nat. Genet. , vol.10 , pp. 486-488
    • Kamboh, M.I.1    Sanghera, D.K.2    Ferrell, R.E.3    Dekosky, S.T.4
  • 68
    • 53549104731 scopus 로고    scopus 로고
    • Alternative medicine and Alzheimer disease
    • Kelley B. J. Knopman D. S. (2008) Alternative medicine and Alzheimer disease. Neurologist 14, 299 306.
    • (2008) Neurologist , vol.14 , pp. 299-306
    • Kelley, B.J.1    Knopman, D.S.2
  • 69
    • 0035957872 scopus 로고    scopus 로고
    • Curcuminoids from Curcuma longa L. (Zingiberaceae) that protect PC12 rat pheochromocytoma and normal human umbilical vein endothelial cells from betaA(1-42) insult
    • Kim D. S., Park S. Y. Kim J. K. (2001) Curcuminoids from Curcuma longa L. (Zingiberaceae) that protect PC12 rat pheochromocytoma and normal human umbilical vein endothelial cells from betaA(1-42) insult. Neurosci. Lett. 303, 57061.
    • (2001) Neurosci. Lett. , vol.303 , pp. 57061
    • Kim, D.S.1    Park, S.Y.2    Kim, J.K.3
  • 70
    • 34447308268 scopus 로고    scopus 로고
    • SIRT1 deacetylase protects against neurodegeneration in models for Alzheimer's disease and amyotrophic lateral sclerosis
    • Kim D., Nguyen M. D., Dobbin M. M. et al. (2007a) SIRT1 deacetylase protects against neurodegeneration in models for Alzheimer's disease and amyotrophic lateral sclerosis. EMBO J. 26, 3169 3179.
    • (2007) EMBO J. , vol.26 , pp. 3169-3179
    • Kim, D.1    Nguyen, M.D.2    Dobbin, M.M.3
  • 71
    • 34547700243 scopus 로고    scopus 로고
    • Epigallocatechin-3-gallate suppresses NF-kappaB activation and phosphorylation of p38 MAPK and JNK in human astrocytoma U373MG cells
    • Kim S. J., Jeong H. J., Lee K. M. et al. (2007b) Epigallocatechin-3- gallate suppresses NF-kappaB activation and phosphorylation of p38 MAPK and JNK in human astrocytoma U373MG cells. J. Nutr. Biochem. 18, 587 596.
    • (2007) J. Nutr. Biochem. , vol.18 , pp. 587-596
    • Kim, S.J.1    Jeong, H.J.2    Lee, K.M.3
  • 72
    • 31944446417 scopus 로고    scopus 로고
    • The effect of epigallocatechin gallate on suppressing disease progression of ALS model mice
    • Koh S. H., Lee S. M., Kim H. Y. et al. (2006) The effect of epigallocatechin gallate on suppressing disease progression of ALS model mice. Neurosci. Lett. 395, 103 107.
    • (2006) Neurosci. Lett. , vol.395 , pp. 103-107
    • Koh, S.H.1    Lee, S.M.2    Kim, H.Y.3
  • 74
    • 33845917602 scopus 로고    scopus 로고
    • Neuroprotective effects of resveratrol against intracerebroventricular colchicine-induced cognitive impairment and oxidative stress in rats
    • DOI 10.1159/000097511
    • Kumar A., Naidu P. S., Seghal N. Padi S. S. (2007) Neuroprotective effects of resveratrol against intracerebroventricular colchicine-induced cognitive impairment and oxidative stress in rats. Pharmacology 79, 17 26. (Pubitemid 46034173)
    • (2007) Pharmacology , vol.79 , Issue.1 , pp. 17-26
    • Kumar, A.1    Naidu, P.S.2    Seghal, N.3    Padi, S.S.V.4
  • 76
    • 0042165908 scopus 로고    scopus 로고
    • Effects of delayed administration of (-)-epigallocatechin gallate, a green tea polyphenol on the changes in polyamine levels and neuronal damage after transient forebrain ischemia in gerbils
    • Lee S. Y., Kim C. Y., Lee J. J., Jung J. G. Lee S. R. (2003) Effects of delayed administration of (-)-epigallocatechin gallate, a green tea polyphenol on the changes in polyamine levels and neuronal damage after transient forebrain ischemia in gerbils. Brain Res. Bull. 61, 399 406.
    • (2003) Brain Res. Bull. , vol.61 , pp. 399-406
    • Lee, S.Y.1    Kim, C.Y.2    Lee, J.J.3    Jung, J.G.4    Lee, S.R.5
  • 77
    • 0034851553 scopus 로고    scopus 로고
    • Green tea polyphenol (-)-epigallocatechin-3-gallate prevents N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced dopaminergic neurodegeneration
    • Levites Y., Weinreb O., Maor G., Youdim M. B. Mandel S. (2001) Green tea polyphenol (-)-epigallocatechin-3-gallate prevents N-methyl-4-phenyl-1,2,3,6- tetrahydropyridine-induced dopaminergic neurodegeneration. J. Neurochem. 78, 1073 1082.
    • (2001) J. Neurochem. , vol.78 , pp. 1073-1082
    • Levites, Y.1    Weinreb, O.2    Maor, G.3    Youdim, M.B.4    Mandel, S.5
  • 78
    • 0037163110 scopus 로고    scopus 로고
    • Involvement of protein kinase C activation and cell survival/cell cycle genes in green tea polyphenol (-)-epigallocatechin 3-gallate neuroprotective action
    • Levites Y., Amit T., Youdim M. B. Mandel S. (2002) Involvement of protein kinase C activation and cell survival/cell cycle genes in green tea polyphenol (-)-epigallocatechin 3-gallate neuroprotective action. J. Biol. Chem. 277, 30574 30580.
    • (2002) J. Biol. Chem. , vol.277 , pp. 30574-30580
    • Levites, Y.1    Amit, T.2    Youdim, M.B.3    Mandel, S.4
  • 79
    • 0038661168 scopus 로고    scopus 로고
    • Neuroprotection and neurorescue against Abeta toxicity and PKC-dependent release of nonamyloidogenic soluble precursor protein by green tea polyphenol (-)-epigallocatechin-3-gallate
    • Levites Y., Amit T., Mandel S. Youdim M. B. (2003) Neuroprotection and neurorescue against Abeta toxicity and PKC-dependent release of nonamyloidogenic soluble precursor protein by green tea polyphenol (-)-epigallocatechin-3- gallate. FASEB J. 17, 952 954.
    • (2003) FASEB J. , vol.17 , pp. 952-954
    • Levites, Y.1    Amit, T.2    Mandel, S.3    Youdim, M.B.4
  • 80
    • 10644230076 scopus 로고    scopus 로고
    • (-)-Epigallocatechin gallate inhibits lipopolysaccharide-induced microglial activation and protects against inflammation-mediated dopaminergic neuronal injury
    • Li R., Huang Y. G., Fang D. Le W. D. (2004) (-)-Epigallocatechin gallate inhibits lipopolysaccharide-induced microglial activation and protects against inflammation-mediated dopaminergic neuronal injury. J. Neurosci. Res. 78, 723 731.
    • (2004) J. Neurosci. Res. , vol.78 , pp. 723-731
    • Li, R.1    Huang, Y.G.2    Fang, D.3    Le, W.D.4
  • 81
    • 39049194011 scopus 로고    scopus 로고
    • Epigallocatechin gallate protects dopaminergic neurons against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity by inhibiting microglial cell activation
    • Li R., Peng N., Du F., Li X. P. Le W. D. (2006) Epigallocatechin gallate protects dopaminergic neurons against 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine-induced neurotoxicity by inhibiting microglial cell activation. Nan Fang Yi Ke Da Xue Xue Bao 26, 376 380.
    • (2006) Nan Fang Yi Ke da Xue Xue Bao , vol.26 , pp. 376-380
    • Li, R.1    Peng, N.2    Du, F.3    Li, X.P.4    Le, W.D.5
  • 82
    • 0035503597 scopus 로고    scopus 로고
    • The curry spice curcumin reduces oxidative damage and amyloid pathology in an Alzheimer transgenic mouse
    • Lim G. P., Chu T., Yang F., Beech W., Frautschy S. A. Cole G. M. (2001) The curry spice curcumin reduces oxidative damage and amyloid pathology in an Alzheimer transgenic mouse. J. Neurosci. 21, 8370 8377.
    • (2001) J. Neurosci. , vol.21 , pp. 8370-8377
    • Lim, G.P.1    Chu, T.2    Yang, F.3    Beech, W.4    Frautschy, S.A.5    Cole, G.M.6
  • 83
    • 0036725818 scopus 로고    scopus 로고
    • Risk factors for Alzheimer's disease: A prospective analysis from the Canadian Study of Health and Aging
    • Lindsay J., Laurin D., Verreault R., Hebert R., Helliwell B., Hill G. B. McDowell I. (2002) Risk factors for Alzheimer's disease: a prospective analysis from the Canadian Study of Health and Aging. Am. J. Epidemiol. 156, 445 453.
    • (2002) Am. J. Epidemiol. , vol.156 , pp. 445-453
    • Lindsay, J.1    Laurin, D.2    Verreault, R.3    Hebert, R.4    Helliwell, B.5    Hill, G.B.6    McDowell, I.7
  • 84
    • 31144450053 scopus 로고    scopus 로고
    • Current pharmacotherapy for Alzheimer's disease
    • Lleo A., Greenberg S. M. Growdon J. H. (2006) Current pharmacotherapy for Alzheimer's disease. Annu. Rev. Med. 57, 513 533.
    • (2006) Annu. Rev. Med. , vol.57 , pp. 513-533
    • Lleo, A.1    Greenberg, S.M.2    Growdon, J.H.3
  • 87
    • 33646244725 scopus 로고    scopus 로고
    • Cholinesterase inhibitors: Drugs looking for a disease?
    • Maggini M., Vanacore N. Raschetti R. (2006) Cholinesterase inhibitors: drugs looking for a disease? PLoS Med. 3, e140.
    • (2006) PLoS Med. , vol.3 , pp. 140
    • Maggini, M.1    Vanacore, N.2    Raschetti, R.3
  • 88
    • 14744287885 scopus 로고    scopus 로고
    • Polyphenols and prevention of cardiovascular diseases
    • Manach C., Mazur A. Scalbert A. (2005) Polyphenols and prevention of cardiovascular diseases. Curr. Opin. Lipidol. 16, 77 84.
    • (2005) Curr. Opin. Lipidol. , vol.16 , pp. 77-84
    • Manach, C.1    Mazur, A.2    Scalbert, A.3
  • 89
    • 20944444111 scopus 로고    scopus 로고
    • Multifunctional activities of green tea catechins in neuroprotection. Modulation of cell survival genes, iron-dependent oxidative stress and PKC signaling pathway
    • Mandel S. A., Avramovich-Tirosh Y., Reznichenko L., Zheng H., Weinreb O., Amit T. Youdim M. B. (2005) Multifunctional activities of green tea catechins in neuroprotection. Modulation of cell survival genes, iron-dependent oxidative stress and PKC signaling pathway. Neuro-Signals 14, 46 60.
    • (2005) Neuro-Signals , vol.14 , pp. 46-60
    • Mandel, S.A.1    Avramovich-Tirosh, Y.2    Reznichenko, L.3    Zheng, H.4    Weinreb, O.5    Amit, T.6    Youdim, M.B.7
  • 90
    • 33644660982 scopus 로고    scopus 로고
    • Green tea catechins as brain-permeable, natural iron chelators- antioxidants for the treatment of neurodegenerative disorders
    • Mandel S., Amit T., Reznichenko L., Weinreb O. Youdim M. B. (2006) Green tea catechins as brain-permeable, natural iron chelators-antioxidants for the treatment of neurodegenerative disorders. Mol. Nutr. Food Res. 50, 229 234.
    • (2006) Mol. Nutr. Food Res. , vol.50 , pp. 229-234
    • Mandel, S.1    Amit, T.2    Reznichenko, L.3    Weinreb, O.4    Youdim, M.B.5
  • 91
    • 27844497059 scopus 로고    scopus 로고
    • Resveratrol promotes clearance of Alzheimer's disease amyloid-beta peptides
    • Marambaud P., Zhao H. Davies P. (2005) Resveratrol promotes clearance of Alzheimer's disease amyloid-beta peptides. J. Biol. Chem. 280, 37377 37382.
    • (2005) J. Biol. Chem. , vol.280 , pp. 37377-37382
    • Marambaud, P.1    Zhao, H.2    Davies, P.3
  • 92
    • 44049102976 scopus 로고    scopus 로고
    • Current and future therapy in Alzheimer's disease
    • van Marum R. J. (2008) Current and future therapy in Alzheimer's disease. Fundam. Clin. Pharmacol. 22, 265 274.
    • (2008) Fundam. Clin. Pharmacol. , vol.22 , pp. 265-274
    • Van Marum, R.J.1
  • 95
    • 3943092621 scopus 로고    scopus 로고
    • Pathways towards and away from Alzheimer's disease
    • Mattson M. P. (2004) Pathways towards and away from Alzheimer's disease. Nature 430, 631 639.
    • (2004) Nature , vol.430 , pp. 631-639
    • Mattson, M.P.1
  • 96
    • 33750159449 scopus 로고    scopus 로고
    • Neurohormetic phytochemicals: Low-dose toxins that induce adaptive neuronal stress responses
    • Mattson M. P. Cheng A. (2006) Neurohormetic phytochemicals: low-dose toxins that induce adaptive neuronal stress responses. Trends Neurosci. 29, 632 639.
    • (2006) Trends Neurosci. , vol.29 , pp. 632-639
    • Mattson, M.P.1    Cheng, A.2
  • 97
    • 60949108706 scopus 로고    scopus 로고
    • Viewpoint: Mechanisms of action and therapeutic potential of neurohormetic phytochemicals
    • Mattson M. P., Son T. G. Camandola S. (2007) Viewpoint: mechanisms of action and therapeutic potential of neurohormetic phytochemicals. Dose Response 5, 174 186.
    • (2007) Dose Response , vol.5 , pp. 174-186
    • Mattson, M.P.1    Son, T.G.2    Camandola, S.3
  • 98
    • 0035835451 scopus 로고    scopus 로고
    • Association between polymorphism in regulatory region of gene encoding tumour necrosis factor alpha and risk of Alzheimer's disease and vascular dementia: A case-control study
    • McCusker S. M., Curran M. D., Dynan K. B., McCullagh C. D., Urquhart D. D., Middleton D., Patterson C. C., McIlroy S. P. Passmore A. P. (2001) Association between polymorphism in regulatory region of gene encoding tumour necrosis factor alpha and risk of Alzheimer's disease and vascular dementia: a case-control study. Lancet 357, 436 439.
    • (2001) Lancet , vol.357 , pp. 436-439
    • McCusker, S.M.1    Curran, M.D.2    Dynan, K.B.3    McCullagh, C.D.4    Urquhart, D.D.5    Middleton, D.6    Patterson, C.C.7    McIlroy, S.P.8    Passmore, A.P.9
  • 99
    • 0242580631 scopus 로고    scopus 로고
    • "Brain-specific" nutrients: A memory cure?
    • McDaniel M. A., Maier S. F. Einstein G. O. (2003) "Brain- specific" nutrients: a memory cure? Nutrition 19, 957 975.
    • (2003) Nutrition , vol.19 , pp. 957-975
    • McDaniel, M.A.1    Maier, S.F.2    Einstein, G.O.3
  • 100
    • 0035693924 scopus 로고    scopus 로고
    • Inflammation, autotoxicity and Alzheimer disease
    • McGeer P. L. McGeer E. G. (2001) Inflammation, autotoxicity and Alzheimer disease. Neurobiol. Aging 22, 799 809.
    • (2001) Neurobiol. Aging , vol.22 , pp. 799-809
    • McGeer, P.L.1    McGeer, E.G.2
  • 101
    • 70849095823 scopus 로고    scopus 로고
    • Curcumin inhibits COPD-like airway inflammation and lung cancer progression in mice
    • Moghaddam S. J., Barta P., Mirabolfathinejad S. G. et al. (2009) Curcumin inhibits COPD-like airway inflammation and lung cancer progression in mice. Carcinogenesis 30, 1949 1956.
    • (2009) Carcinogenesis , vol.30 , pp. 1949-1956
    • Moghaddam, S.J.1    Barta, P.2    Mirabolfathinejad, S.G.3
  • 102
    • 34248146970 scopus 로고    scopus 로고
    • Effect of resveratrol on antioxidant enzyme activities in the brain of healthy rat
    • Mokni M., Elkahoui S., Limam F., Amri M. Aouani E. (2007) Effect of resveratrol on antioxidant enzyme activities in the brain of healthy rat. Neurochem. Res. 32, 981 987.
    • (2007) Neurochem. Res. , vol.32 , pp. 981-987
    • Mokni, M.1    Elkahoui, S.2    Limam, F.3    Amri, M.4    Aouani, E.5
  • 103
    • 84984755327 scopus 로고    scopus 로고
    • A beta peptide vaccination prevents memory loss in an animal model of Alzheimer's disease
    • Morgan D., Diamond D. M., Gottschall P. E. et al. (2000) A beta peptide vaccination prevents memory loss in an animal model of Alzheimer's disease. Nature 408, 982 985.
    • (2000) Nature , vol.408 , pp. 982-985
    • Morgan, D.1    Diamond, D.M.2    Gottschall, P.E.3
  • 104
    • 0034655773 scopus 로고    scopus 로고
    • Curcumin, an antioxidant and anti-inflammatory agent, induces heme oxygenase-1 and protects endothelial cells against oxidative stress
    • Motterlini R., Foresti R., Bassi R. Green C. J. (2000) Curcumin, an antioxidant and anti-inflammatory agent, induces heme oxygenase-1 and protects endothelial cells against oxidative stress. Free Radic. Biol. Med. 28, 1303 1312.
    • (2000) Free Radic. Biol. Med. , vol.28 , pp. 1303-1312
    • Motterlini, R.1    Foresti, R.2    Bassi, R.3    Green, C.J.4
  • 105
    • 0031441473 scopus 로고    scopus 로고
    • Absorption and distribution of tea catechin, (-)-epigallocatechin-3- gallate, in the rat
    • Nakagawa K. Miyazawa T. (1997) Absorption and distribution of tea catechin, (-)-epigallocatechin-3-gallate, in the rat. J. Nutr. Sci. Vitaminol. 43, 679 684.
    • (1997) J. Nutr. Sci. Vitaminol. , vol.43 , pp. 679-684
    • Nakagawa, K.1    Miyazawa, T.2
  • 107
    • 0034053173 scopus 로고    scopus 로고
    • Association of interleukin-1 gene polymorphisms with Alzheimer's disease
    • Nicoll J. A., Mrak R. E., Graham D. I. et al. (2000) Association of interleukin-1 gene polymorphisms with Alzheimer's disease. Ann. Neurol. 47, 365 368.
    • (2000) Ann. Neurol. , vol.47 , pp. 365-368
    • Nicoll, J.A.1    Mrak, R.E.2    Graham, D.I.3
  • 108
    • 0036292827 scopus 로고    scopus 로고
    • Protective effects of green tea polyphenols and their major component, (-)-epigallocatechin-3-gallate (EGCG), on 6-hydroxydopamine-induced apoptosis in PC12 cells
    • Nie G., Cao Y. Zhao B. (2002a) Protective effects of green tea polyphenols and their major component, (-)-epigallocatechin-3-gallate (EGCG), on 6-hydroxydopamine-induced apoptosis in PC12 cells. Redox Rep 7, 171 177.
    • (2002) Redox Rep , vol.7 , pp. 171-177
    • Nie, G.1    Cao, Y.2    Zhao, B.3
  • 109
    • 0036329717 scopus 로고    scopus 로고
    • Distinct effects of tea catechins on 6-hydroxydopamine-induced apoptosis in PC12 cells
    • Nie G., Jin C., Cao Y., Shen S. Zhao B. (2002b) Distinct effects of tea catechins on 6-hydroxydopamine-induced apoptosis in PC12 cells. Arch. Biochem. Biophys. 397, 84 90.
    • (2002) Arch. Biochem. Biophys. , vol.397 , pp. 84-90
    • Nie, G.1    Jin, C.2    Cao, Y.3    Shen, S.4    Zhao, B.5
  • 111
    • 33745209915 scopus 로고    scopus 로고
    • ADAM10 activation is required for green tea (-)-epigallocatechin-3- gallate-induced alpha-secretase cleavage of amyloid precursor protein
    • Obregon D. F., Rezai-Zadeh K., Bai Y. et al. (2006) ADAM10 activation is required for green tea (-)-epigallocatechin-3-gallate-induced alpha-secretase cleavage of amyloid precursor protein. J. Biol. Chem. 281, 16419 16427.
    • (2006) J. Biol. Chem. , vol.281 , pp. 16419-16427
    • Obregon, D.F.1    Rezai-Zadeh, K.2    Bai, Y.3
  • 112
    • 0141642253 scopus 로고    scopus 로고
    • Potent anti-amyloidogenic and fibril-destabilizing effects of polyphenols in vitro: Implications for the prevention and therapeutics of Alzheimer's disease
    • Ono K., Yoshiike Y., Takashima A., Hasegawa K., Naiki H. Yamada M. (2003) Potent anti-amyloidogenic and fibril-destabilizing effects of polyphenols in vitro: implications for the prevention and therapeutics of Alzheimer's disease. J. Neurochem. 87, 172 181.
    • (2003) J. Neurochem. , vol.87 , pp. 172-181
    • Ono, K.1    Yoshiike, Y.2    Takashima, A.3    Hasegawa, K.4    Naiki, H.5    Yamada, M.6
  • 113
    • 1542364225 scopus 로고    scopus 로고
    • Curcumin has potent anti-amyloidogenic effects for Alzheimer's beta-amyloid fibrils in vitro
    • Ono K., Hasegawa K., Naiki H. Yamada M. (2004) Curcumin has potent anti-amyloidogenic effects for Alzheimer's beta-amyloid fibrils in vitro. J. Neurosci. Res. 75, 742 750.
    • (2004) J. Neurosci. Res. , vol.75 , pp. 742-750
    • Ono, K.1    Hasegawa, K.2    Naiki, H.3    Yamada, M.4
  • 115
    • 10744230547 scopus 로고    scopus 로고
    • Subacute meningoencephalitis in a subset of patients with AD after Abeta42 immunization
    • Orgogozo J. M., Gilman S., Dartigues J. F. et al. (2003) Subacute meningoencephalitis in a subset of patients with AD after Abeta42 immunization. Neurology 61, 46 54.
    • (2003) Neurology , vol.61 , pp. 46-54
    • Orgogozo, J.M.1    Gilman, S.2    Dartigues, J.F.3
  • 117
    • 16344364163 scopus 로고    scopus 로고
    • Epigallocatechin gallate inhibits aryl hydrocarbon receptor gene transcription through an indirect mechanism involving binding to a 90 kDa heat shock protein
    • Palermo C. M., Westlake C. A. Gasiewicz T. A. (2005) Epigallocatechin gallate inhibits aryl hydrocarbon receptor gene transcription through an indirect mechanism involving binding to a 90 kDa heat shock protein. Biochemistry 44, 5041 5052.
    • (2005) Biochemistry , vol.44 , pp. 5041-5052
    • Palermo, C.M.1    Westlake, C.A.2    Gasiewicz, T.A.3
  • 119
    • 0032914896 scopus 로고    scopus 로고
    • A genetic variation of the inflammatory cytokine interleukin-6 delays the initial onset and reduces the risk for sporadic Alzheimer's disease
    • Papassotiropoulos A., Bagli M., Jessen F., Bayer T. A., Maier W., Rao M. L. Heun R. (1999) A genetic variation of the inflammatory cytokine interleukin-6 delays the initial onset and reduces the risk for sporadic Alzheimer's disease. Ann. Neurol. 45, 666 668.
    • (1999) Ann. Neurol. , vol.45 , pp. 666-668
    • Papassotiropoulos, A.1    Bagli, M.2    Jessen, F.3    Bayer, T.A.4    Maier, W.5    Rao, M.L.6    Heun, R.7
  • 120
    • 0030248270 scopus 로고    scopus 로고
    • Microglial cells internalize aggregates of the Alzheimer's disease amyloid beta-protein via a scavenger receptor
    • Paresce D. M., Ghosh R. N. Maxfield F. R. (1996) Microglial cells internalize aggregates of the Alzheimer's disease amyloid beta-protein via a scavenger receptor. Neuron 17, 553 565.
    • (1996) Neuron , vol.17 , pp. 553-565
    • Paresce, D.M.1    Ghosh, R.N.2    Maxfield, F.R.3
  • 122
    • 0035826546 scopus 로고    scopus 로고
    • Investigation of association of 13 polymorphisms in eight genes in southeastern African American Alzheimer disease patients as compared to age-matched controls
    • Perry R. T., Collins J. S., Harrell L. E., Acton R. T. Go R. C. (2001) Investigation of association of 13 polymorphisms in eight genes in southeastern African American Alzheimer disease patients as compared to age-matched controls. Am. J. Med. Genet. 105, 332 342.
    • (2001) Am. J. Med. Genet. , vol.105 , pp. 332-342
    • Perry, R.T.1    Collins, J.S.2    Harrell, L.E.3    Acton, R.T.4    Go, R.C.5
  • 124
    • 56349145099 scopus 로고    scopus 로고
    • Oxidative stress hypothesis in Alzheimer's disease: A reappraisal
    • Pratico D. (2008) Oxidative stress hypothesis in Alzheimer's disease: a reappraisal. Trends Pharmacol. Sci. 29, 609 615.
    • (2008) Trends Pharmacol. Sci. , vol.29 , pp. 609-615
    • Pratico, D.1
  • 125
    • 2342420034 scopus 로고    scopus 로고
    • Lipid peroxidation and oxidative imbalance: Early functional events in Alzheimer's disease
    • Pratico D. Sung S. (2004) Lipid peroxidation and oxidative imbalance: early functional events in Alzheimer's disease. J. Alzheimers Dis. 6, 171 175.
    • (2004) J. Alzheimers Dis. , vol.6 , pp. 171-175
    • Pratico, D.1    Sung, S.2
  • 126
    • 0036845314 scopus 로고    scopus 로고
    • Microglia enhance beta-amyloid peptide-induced toxicity in cortical and mesencephalic neurons by producing reactive oxygen species
    • Qin L., Liu Y., Cooper C., Liu B., Wilson B. Hong J. S. (2002) Microglia enhance beta-amyloid peptide-induced toxicity in cortical and mesencephalic neurons by producing reactive oxygen species. J. Neurochem. 83, 973 983.
    • (2002) J. Neurochem. , vol.83 , pp. 973-983
    • Qin, L.1    Liu, Y.2    Cooper, C.3    Liu, B.4    Wilson, B.5    Hong, J.S.6
  • 127
    • 33750532308 scopus 로고    scopus 로고
    • Regulation of inflammation and redox signaling by dietary polyphenols
    • DOI 10.1016/j.bcp.2006.07.004, PII S0006295206004199, Cell Signalling, Transcription and Translation as Therapeutic Tergets
    • Rahman I., Biswas S. K. Kirkham P. A. (2006) Regulation of inflammation and redox signaling by dietary polyphenols. Biochem. Pharmacol. 72, 1439 1452. (Pubitemid 44666744)
    • (2006) Biochemical Pharmacology , vol.72 , Issue.11 , pp. 1439-1452
    • Rahman, I.1    Biswas, S.K.2    Kirkham, P.A.3
  • 128
    • 42049109707 scopus 로고    scopus 로고
    • Inhibition of monoamine oxidase-B by the polyphenolic compound, curcumin and its metabolite tetrahydrocurcumin, in a model of Parkinson's disease induced by MPTP neurodegeneration in mice
    • Rajeswari A. Sabesan M. (2008) Inhibition of monoamine oxidase-B by the polyphenolic compound, curcumin and its metabolite tetrahydrocurcumin, in a model of Parkinson's disease induced by MPTP neurodegeneration in mice. Inflammopharmacology 16, 96 99.
    • (2008) Inflammopharmacology , vol.16 , pp. 96-99
    • Rajeswari, A.1    Sabesan, M.2
  • 129
    • 84934436223 scopus 로고    scopus 로고
    • Regulation of COX and LOX by curcumin
    • Rao C. V. (2007) Regulation of COX and LOX by curcumin. Adv. Exp. Med. Biol. 595, 213 226.
    • (2007) Adv. Exp. Med. Biol. , vol.595 , pp. 213-226
    • Rao, C.V.1
  • 130
    • 39149122810 scopus 로고    scopus 로고
    • Amyloid beta, mitochondrial dysfunction and synaptic damage: Implications for cognitive decline in aging and Alzheimer's disease
    • Reddy P. H. Beal M. F. (2008) Amyloid beta, mitochondrial dysfunction and synaptic damage: implications for cognitive decline in aging and Alzheimer's disease. Trends Mol. Med. 14, 45 53.
    • (2008) Trends Mol. Med. , vol.14 , pp. 45-53
    • Reddy, P.H.1    Beal, M.F.2
  • 131
    • 25444500410 scopus 로고    scopus 로고
    • Green tea epigallocatechin-3-gallate (EGCG) modulates amyloid precursor protein cleavage and reduces cerebral amyloidosis in Alzheimer transgenic mice
    • Rezai-Zadeh K., Shytle D., Sun N. et al. (2005) Green tea epigallocatechin-3-gallate (EGCG) modulates amyloid precursor protein cleavage and reduces cerebral amyloidosis in Alzheimer transgenic mice. J. Neurosci. 25, 8807 8814.
    • (2005) J. Neurosci. , vol.25 , pp. 8807-8814
    • Rezai-Zadeh, K.1    Shytle, D.2    Sun, N.3
  • 132
    • 44249116000 scopus 로고    scopus 로고
    • Green tea epigallocatechin-3-gallate (EGCG) reduces beta-amyloid mediated cognitive impairment and modulates tau pathology in Alzheimer transgenic mice
    • Rezai-Zadeh K., Arendash G. W., Hou H., Fernandez F., Jensen M., Runfeldt M., Shytle R. D. Tan J. (2008) Green tea epigallocatechin-3-gallate (EGCG) reduces beta-amyloid mediated cognitive impairment and modulates tau pathology in Alzheimer transgenic mice. Brain Res. 1214, 177 187.
    • (2008) Brain Res. , vol.1214 , pp. 177-187
    • Rezai-Zadeh, K.1    Arendash, G.W.2    Hou, H.3    Fernandez, F.4    Jensen, M.5    Runfeldt, M.6    Shytle, R.D.7    Tan, J.8
  • 134
    • 38349053821 scopus 로고    scopus 로고
    • Molecular mechanisms of oxidative stress resistance induced by resveratrol: Specific and progressive induction of MnSOD
    • Robb E. L., Page M. M., Wiens B. E. Stuart J. A. (2008) Molecular mechanisms of oxidative stress resistance induced by resveratrol: specific and progressive induction of MnSOD. Biochem. Biophys. Res. Commun. 367, 406 412.
    • (2008) Biochem. Biophys. Res. Commun. , vol.367 , pp. 406-412
    • Robb, E.L.1    Page, M.M.2    Wiens, B.E.3    Stuart, J.A.4
  • 135
    • 33750731675 scopus 로고    scopus 로고
    • 100 years and counting: Prospects for defeating Alzheimer's disease
    • Roberson E. D. Mucke L. (2006) 100 years and counting: prospects for defeating Alzheimer's disease. Science 314, 781 784.
    • (2006) Science , vol.314 , pp. 781-784
    • Roberson, E.D.1    Mucke, L.2
  • 136
    • 0026447529 scopus 로고
    • Complement activation by beta-amyloid in Alzheimer disease
    • Rogers J., Cooper N. R., Webster S. et al. (1992) Complement activation by beta-amyloid in Alzheimer disease. Proc. Natl Acad. Sci. USA 89, 10016 10020.
    • (1992) Proc. Natl Acad. Sci. USA , vol.89 , pp. 10016-10020
    • Rogers, J.1    Cooper, N.R.2    Webster, S.3
  • 137
    • 0027268393 scopus 로고
    • Clinical trial of indomethacin in Alzheimer's disease
    • Rogers J., Kirby L. C., Hempelman S. R. et al. (1993) Clinical trial of indomethacin in Alzheimer's disease. Neurology 43, 1609 1611.
    • (1993) Neurology , vol.43 , pp. 1609-1611
    • Rogers, J.1    Kirby, L.C.2    Hempelman, S.R.3
  • 139
    • 0242609178 scopus 로고    scopus 로고
    • Nonsteroidal anti-inflammatory drugs and peroxisome proliferator- activated receptor-gamma agonists modulate immunostimulated processing of amyloid precursor protein through regulation of beta-secretase
    • Sastre M., Dewachter I., Landreth G. E., Willson T. M., Klockgether T., van Leuven F. Heneka M. T. (2003) Nonsteroidal anti-inflammatory drugs and peroxisome proliferator-activated receptor-gamma agonists modulate immunostimulated processing of amyloid precursor protein through regulation of beta-secretase. J. Neurosci. 23, 9796 9804.
    • (2003) J. Neurosci. , vol.23 , pp. 9796-9804
    • Sastre, M.1    Dewachter, I.2    Landreth, G.E.3    Willson, T.M.4    Klockgether, T.5    Van Leuven, F.6    Heneka, M.T.7
  • 142
    • 0033551547 scopus 로고    scopus 로고
    • A double-blind, placebo-controlled trial of diclofenac/misoprostol in Alzheimer's disease
    • Scharf S., Mander A., Ugoni A., Vajda F. Christophidis N. (1999) A double-blind, placebo-controlled trial of diclofenac/misoprostol in Alzheimer's disease. Neurology 53, 197 201.
    • (1999) Neurology , vol.53 , pp. 197-201
    • Scharf, S.1    Mander, A.2    Ugoni, A.3    Vajda, F.4    Christophidis, N.5
  • 143
    • 0033536163 scopus 로고    scopus 로고
    • Immunization with amyloid-beta attenuates Alzheimer-disease-like pathology in the PDAPP mouse
    • Schenk D., Barbour R., Dunn W. et al. (1999) Immunization with amyloid-beta attenuates Alzheimer-disease-like pathology in the PDAPP mouse. Nature 400, 173 177.
    • (1999) Nature , vol.400 , pp. 173-177
    • Schenk, D.1    Barbour, R.2    Dunn, W.3
  • 144
    • 8544257019 scopus 로고    scopus 로고
    • Heme oxygenase expression in human central nervous system disorders
    • Schipper H. M. (2004) Heme oxygenase expression in human central nervous system disorders. Free Radic. Biol. Med. 37, 1995 2011.
    • (2004) Free Radic. Biol. Med. , vol.37 , pp. 1995-2011
    • Schipper, H.M.1
  • 145
    • 63249137056 scopus 로고    scopus 로고
    • Development of affitope vaccines for Alzheimer's disease (AD) - From concept to clinical testing
    • Schneeberger A., Mandler M., Otawa O., Zauner W., Mattner F. Schmidt W. (2009) Development of affitope vaccines for Alzheimer's disease (AD) - from concept to clinical testing. J. Nutr. Health Aging 13, 264 267.
    • (2009) J. Nutr. Health Aging , vol.13 , pp. 264-267
    • Schneeberger, A.1    Mandler, M.2    Otawa, O.3    Zauner, W.4    Mattner, F.5    Schmidt, W.6
  • 147
    • 0029784838 scopus 로고    scopus 로고
    • Amyloid beta-protein and the genetics of Alzheimer's disease
    • Selkoe D. J. (1996) Amyloid beta-protein and the genetics of Alzheimer's disease. J. Biol. Chem. 271, 18295 18298.
    • (1996) J. Biol. Chem. , vol.271 , pp. 18295-18298
    • Selkoe, D.J.1
  • 148
    • 0037063709 scopus 로고    scopus 로고
    • Chronic treatment with transresveratrol prevents intracerebroventricular streptozotocin induced cognitive impairment and oxidative stress in rats
    • Sharma M. Gupta Y. K. (2002) Chronic treatment with transresveratrol prevents intracerebroventricular streptozotocin induced cognitive impairment and oxidative stress in rats. Life Sci. 71, 2489 2498.
    • (2002) Life Sci. , vol.71 , pp. 2489-2498
    • Sharma, M.1    Gupta, Y.K.2
  • 149
    • 27644457456 scopus 로고    scopus 로고
    • Effect of alpha lipoic acid, melatonin and trans resveratrol on intracerebroventricular streptozotocin induced spatial memory deficit in rats
    • Sharma M., Briyal S. Gupta Y. K. (2005) Effect of alpha lipoic acid, melatonin and trans resveratrol on intracerebroventricular streptozotocin induced spatial memory deficit in rats. Indian J. Physiol. Pharmacol. 49, 395 402.
    • (2005) Indian J. Physiol. Pharmacol. , vol.49 , pp. 395-402
    • Sharma, M.1    Briyal, S.2    Gupta, Y.K.3
  • 150
    • 0027270278 scopus 로고
    • Inhibition of 8-hydroxydeoxyguanosine formation by curcumin in mouse fibroblast cells
    • Shih C. A. Lin J. K. (1993) Inhibition of 8-hydroxydeoxyguanosine formation by curcumin in mouse fibroblast cells. Carcinogenesis 14, 709 712.
    • (1993) Carcinogenesis , vol.14 , pp. 709-712
    • Shih, C.A.1    Lin, J.K.2
  • 152
    • 0028867742 scopus 로고
    • Activation of transcription factor NF-kappa B is suppressed by curcumin (diferuloylmethane) [corrected]
    • Singh S. Aggarwal B. B. (1995) Activation of transcription factor NF-kappa B is suppressed by curcumin (diferuloylmethane) [corrected]. J. Biol. Chem. 270, 24995 25000.
    • (1995) J. Biol. Chem. , vol.270 , pp. 24995-25000
    • Singh, S.1    Aggarwal, B.B.2
  • 153
    • 47849120398 scopus 로고    scopus 로고
    • Challenges for research on polyphenols from foods in Alzheimer's disease: Bioavailability, metabolism, and cellular and molecular mechanisms
    • Singh M., Arseneault M., Sanderson T., Murthy V. Ramassamy C. (2008) Challenges for research on polyphenols from foods in Alzheimer's disease: bioavailability, metabolism, and cellular and molecular mechanisms. J. Agric. Food Chem. 56, 4855 4873.
    • (2008) J. Agric. Food Chem. , vol.56 , pp. 4855-4873
    • Singh, M.1    Arseneault, M.2    Sanderson, T.3    Murthy, V.4    Ramassamy, C.5
  • 155
    • 0030963473 scopus 로고    scopus 로고
    • Resveratrol: A molecule whose time has come? and gone?
    • Soleas G. J., Diamandis E. P. Goldberg D. M. (1997) Resveratrol: a molecule whose time has come? And gone? Clin. Biochem. 30, 91 113.
    • (1997) Clin. Biochem. , vol.30 , pp. 91-113
    • Soleas, G.J.1    Diamandis, E.P.2    Goldberg, D.M.3
  • 157
    • 0031595920 scopus 로고    scopus 로고
    • Wide distribution of [3H](-)-epigallocatechin gallate, a cancer preventive tea polyphenol, in mouse tissue
    • Suganuma M., Okabe S., Oniyama M., Tada Y., Ito H. Fujiki H. (1998) Wide distribution of [3H](-)-epigallocatechin gallate, a cancer preventive tea polyphenol, in mouse tissue. Carcinogenesis 19, 1771 1776.
    • (1998) Carcinogenesis , vol.19 , pp. 1771-1776
    • Suganuma, M.1    Okabe, S.2    Oniyama, M.3    Tada, Y.4    Ito, H.5    Fujiki, H.6
  • 158
    • 4944258716 scopus 로고    scopus 로고
    • The role of inflammation in Alzheimer's disease
    • Tuppo E. E. Arias H. R. (2005) The role of inflammation in Alzheimer's disease. Int. J. Biochem. Cell Biol. 37, 289 305.
    • (2005) Int. J. Biochem. Cell Biol. , vol.37 , pp. 289-305
    • Tuppo, E.E.1    Arias, H.R.2
  • 160
    • 0035845325 scopus 로고    scopus 로고
    • Effect of hydroxychloroquine on progression of dementia in early Alzheimer's disease: An 18-month randomised, double-blind, placebo-controlled study
    • Van Gool W. A., Weinstein H. C., Scheltens P. Walstra G. J. (2001) Effect of hydroxychloroquine on progression of dementia in early Alzheimer's disease: an 18-month randomised, double-blind, placebo-controlled study. Lancet 358, 455 460.
    • (2001) Lancet , vol.358 , pp. 455-460
    • Van Gool, W.A.1    Weinstein, H.C.2    Scheltens, P.3    Walstra, G.J.4
  • 162
    • 0033993607 scopus 로고    scopus 로고
    • Partial neuroprotection of in vivo excitotoxic brain damage by chronic administration of the red wine antioxidant agent, trans-resveratrol in rats
    • Virgili M. Contestabile A. (2000) Partial neuroprotection of in vivo
    • (2000) Neurosci. Lett. , vol.281 , pp. 123-126
    • Virgili, M.1    Contestabile, A.2
  • 164
    • 65649105139 scopus 로고    scopus 로고
    • Curcumin attenuates 6-hydroxydopamine-induced cytotoxicity by anti-oxidation and nuclear factor-kappaB modulation in MES23.5 cells
    • Wang J., Du X. X., Jiang H. Xie J. X. (2009) Curcumin attenuates 6-hydroxydopamine-induced cytotoxicity by anti-oxidation and nuclear factor-kappaB modulation in MES23.5 cells. Biochem. Pharmacol. 78, 178 183.
    • (2009) Biochem. Pharmacol. , vol.78 , pp. 178-183
    • Wang, J.1    Du, X.X.2    Jiang, H.3    Xie, J.X.4
  • 165
    • 29044433921 scopus 로고    scopus 로고
    • Inhibition of lipid peroxidation and protein oxidation in rat liver mitochondria by curcumin and its analogues
    • Wei Q. Y., Chen W. F., Zhou B., Yang L. Liu Z. L. (2006) Inhibition of lipid peroxidation and protein oxidation in rat liver mitochondria by curcumin and its analogues. Biochim. Biophys. Acta 1760, 70 77.
    • (2006) Biochim. Biophys. Acta , vol.1760 , pp. 70-77
    • Wei, Q.Y.1    Chen, W.F.2    Zhou, B.3    Yang, L.4    Liu, Z.L.5
  • 167
    • 33646179260 scopus 로고    scopus 로고
    • Upregulation of heme oxygenase-1 by epigallocatechin-3-gallate via the phosphatidylinositol 3-kinase/Akt and ERK pathways
    • Wu C. C., Hsu M. C., Hsieh C. W., Lin J. B., Lai P. H. Wung B. S. (2006) Upregulation of heme oxygenase-1 by epigallocatechin-3-gallate via the phosphatidylinositol 3-kinase/Akt and ERK pathways. Life Sci. 78, 2889 2897.
    • (2006) Life Sci. , vol.78 , pp. 2889-2897
    • Wu, C.C.1    Hsu, M.C.2    Hsieh, C.W.3    Lin, J.B.4    Lai, P.H.5    Wung, B.S.6
  • 168
    • 0032917904 scopus 로고    scopus 로고
    • Chemokines/chemokine receptors in the central nervous system and Alzheimer's disease
    • Xia M. Q. Hyman B. T. (1999) Chemokines/chemokine receptors in the central nervous system and Alzheimer's disease. J. Neurovirol. 5, 32 41.
    • (1999) J. Neurovirol. , vol.5 , pp. 32-41
    • Xia, M.Q.1    Hyman, B.T.2
  • 170
    • 20044370990 scopus 로고    scopus 로고
    • Curcumin inhibits formation of amyloid beta oligomers and fibrils, binds plaques, and reduces amyloid in vivo
    • Yang F., Lim G. P., Begum A. N. et al. (2005) Curcumin inhibits formation of amyloid beta oligomers and fibrils, binds plaques, and reduces amyloid in vivo. J. Biol. Chem. 280, 5892 5901.
    • (2005) J. Biol. Chem. , vol.280 , pp. 5892-5901
    • Yang, F.1    Lim, G.P.2    Begum, A.N.3
  • 171
    • 0033061855 scopus 로고    scopus 로고
    • Up-regulated production and activation of the complement system in Alzheimer's disease brain
    • Yasojima K., Schwab C., McGeer E. G. McGeer P. L. (1999) Up-regulated production and activation of the complement system in Alzheimer's disease brain. Am. J. Pathol. 154, 927 936.
    • (1999) Am. J. Pathol. , vol.154 , pp. 927-936
    • Yasojima, K.1    Schwab, C.2    McGeer, E.G.3    McGeer, P.L.4
  • 173
    • 0037167542 scopus 로고    scopus 로고
    • Reduced incidence of AD with NSAID but not H2 receptor antagonists: The Cache County Study
    • Zandi P. P., Anthony J. C., Hayden K. M., Mehta K., Mayer L. Breitner J. C. (2002) Reduced incidence of AD with NSAID but not H2 receptor antagonists: the Cache County Study. Neurology 59, 880 886.
    • (2002) Neurology , vol.59 , pp. 880-886
    • Zandi, P.P.1    Anthony, J.C.2    Hayden, K.M.3    Mehta, K.4    Mayer, L.5    Breitner, J.C.6
  • 174
    • 25444508963 scopus 로고    scopus 로고
    • Neuroprotective properties of the natural phenolic antioxidants curcumin and naringenin but not quercetin and fisetin in a 6-OHDA model of Parkinson's disease
    • Zbarsky V., Datla K. P., Parkar S., Rai D. K., Aruoma O. I. Dexter D. T. (2005) Neuroprotective properties of the natural phenolic antioxidants curcumin and naringenin but not quercetin and fisetin in a 6-OHDA model of Parkinson's disease. Free Radic. Res. 39, 1119 1125.
    • (2005) Free Radic. Res. , vol.39 , pp. 1119-1125
    • Zbarsky, V.1    Datla, K.P.2    Parkar, S.3    Rai, D.K.4    Aruoma, O.I.5    Dexter, D.T.6
  • 175
    • 0024652076 scopus 로고
    • Scavenging effect of extracts of green tea and natural antioxidants on active oxygen radicals
    • Zhao B. L., Li X. J., He R. G., Cheng S. J. Xin W. J. (1989) Scavenging effect of extracts of green tea and natural antioxidants on active oxygen radicals. Cell Biophys. 14, 175 185.
    • (1989) Cell Biophys. , vol.14 , pp. 175-185
    • Zhao, B.L.1    Li, X.J.2    He, R.G.3    Cheng, S.J.4    Xin, W.J.5
  • 176
    • 0037713341 scopus 로고    scopus 로고
    • Potential mechanism by which resveratrol, a red wine constituent, protects neurons
    • Zhuang H., Kim Y. S., Koehler R. C. Dore S. (2003) Potential mechanism by which resveratrol, a red wine constituent, protects neurons. Ann. N Y Acad. Sci. 993, 276 286.
    • (2003) Ann. N y Acad. Sci. , vol.993 , pp. 276-286
    • Zhuang, H.1    Kim, Y.S.2    Koehler, R.C.3    Dore, S.4


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