Quercetin potentiates insulin secretion and protects INS-1 pancreatic -cells against oxidative damage via the ERK1/2 pathway

British Journal of Pharmacology

Volumn 161, Issue 4, 2010, Pages 799-814

  Youl, E ^a   Bardy, G ^a   Magous, R ^a   Cros, G ^a   Sejalon, F ^a   Virsolvy, A ^b   Richard, S ^b   Quignard, J F ^c   Gross, R ^a   Petit, P ^a   Bataille, D ^a   Oiry, C ^a  

^a EA7288   (France)

^b HÔPITAL ARNAUD DE VILLENEUVE   (France)

^c CENTRE DE RECHERCHE CARDIO THORACIQUE DE BORDEAUX   (France)

Author keywords

cell viability; diabetes; ERK1 2; insulin secretion; oxidative stress; pancreatic cells; quercetin

Indexed keywords

ACETYLCYSTEINE; ANTIOXIDANT; CALCIUM ION; GLIBENCLAMIDE; GLUCOSE; HYDROGEN PEROXIDE; INSULIN; INSULIN RECEPTOR SUBSTRATE 1; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; QUERCETIN; RESVERATROL;

ANIMAL CELL; ARTICLE; CALCIUM CELL LEVEL; CELL VIABILITY; CONTROLLED STUDY; DIABETES MELLITUS; DRUG EFFECT; DRUG POTENTIATION; ENZYME ACTIVATION; GLUCOSE BLOOD LEVEL; INSULIN RELEASE; NONHUMAN; OXIDATIVE STRESS; PANCREAS ISLET BETA CELL; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

ACETYLCYSTEINE; ANIMALS; ANTIOXIDANTS; CELL LINE; GLUCOSE; GLYBURIDE; HYDROGEN PEROXIDE; HYPOGLYCEMIC AGENTS; INSULIN; INSULIN-SECRETING CELLS; MALE; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; OXIDATIVE STRESS; PHOSPHORYLATION; QUERCETIN; RATS; RATS, WISTAR; SIGNAL TRANSDUCTION; STILBENES;

EID: 77957229744     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/j.1476-5381.2010.00910.x     Document Type: Article

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