-
2
-
-
0031444312
-
Green tea constituent epigallocatechin-3-gallate and induction of apoptosis and cell cycle arrest in human carcinoma cells
-
Ahmad N, Feyes DK, Nieminen AL, Agarwal R, Mukhtar H. Green tea constituent epigallocatechin-3-gallate and induction of apoptosis and cell cycle arrest in human carcinoma cells. J Natl Cancer Inst 1997;89:1881-6.
-
(1997)
J Natl Cancer Inst
, vol.89
, pp. 1881-1886
-
-
Ahmad, N.1
Feyes, D.K.2
Nieminen, A.L.3
Agarwal, R.4
Mukhtar, H.5
-
4
-
-
0034726720
-
Cell cycle dysregulation by green tea polyphenol epigallocatechin-3- gallate
-
Ahmad N, Cheng P, Mukhtar H. Cell cycle dysregulation by green tea polyphenol epigallocatechin-3-gallate. Biochem Biophys Res Commun 2000;275:328-34.
-
(2000)
Biochem Biophys Res Commun
, vol.275
, pp. 328-334
-
-
Ahmad, N.1
Cheng, P.2
Mukhtar, H.3
-
6
-
-
0035861744
-
Effect of glutathione depletion on antitumor drug toxicity (apoptosis and necrosis) in U937 human promyelocytic cells
-
Troyano A, Fernandez C, Sancho P, de Blas E, Alter P. Effect of glutathione depletion on antitumor drug toxicity (apoptosis and necrosis) in U937 human promyelocytic cells. J Biol Chem 2001;276:47107-15.
-
(2001)
J Biol Chem
, vol.276
, pp. 47107-47115
-
-
Troyano, A.1
Fernandez, C.2
Sancho, P.3
De Blas, E.4
Alter, P.5
-
7
-
-
0344806276
-
Prooxidant toxicity of polyphenolic antioxidants to HL-60 cells: Description of quantitative structure-activity relationship
-
Sergediene E, Jönsson K, Szymusiak H, Tyrakowska B, Rietjens IMCM, Cenas N. Prooxidant toxicity of polyphenolic antioxidants to HL-60 cells: description of quantitative structure-activity relationship. FEBS Lett 1999;462:392-6.
-
(1999)
FEBS Lett
, vol.462
, pp. 392-396
-
-
Sergediene, E.1
Jönsson, K.2
Szymusiak, H.3
Tyrakowska, B.4
Rietjens, I.M.C.M.5
Cenas, N.6
-
8
-
-
0035437189
-
Ascorbic acid enhances arsenic trioxide-induced cytotoxicity in multiple myeloma cells
-
Grad JM, Bahlis NJ, Reis I, Oshiro MM, Dalton WS, Boise LH. Ascorbic acid enhances arsenic trioxide-induced cytotoxicity in multiple myeloma cells. Blood 2001;98:805-13.
-
(2001)
Blood
, vol.98
, pp. 805-813
-
-
Grad, J.M.1
Bahlis, N.J.2
Reis, I.3
Oshiro, M.M.4
Dalton, W.S.5
Boise, L.H.6
-
9
-
-
0037099645
-
Mechanism of action of arsenic trioxide
-
Miller WH, Jr., Schipper HM, Lee JS, Singer J, Waxman S. Mechanism of action of arsenic trioxide. Cancer Res 2002;62:3893-903.
-
(2002)
Cancer Res
, vol.62
, pp. 3893-3903
-
-
Miller Jr., W.H.1
Schipper, H.M.2
Lee, J.S.3
Singer, J.4
Waxman, S.5
-
10
-
-
0032933610
-
Malignant cells can be sensitized to undergo growth inhibition and apoptosis by arsenic trioxide through modulation of the glutathione redox system
-
Dai J, Weinberg RS, Waxman S, Jing Y. Malignant cells can be sensitized to undergo growth inhibition and apoptosis by arsenic trioxide through modulation of the glutathione redox system. Blood 1999;93:268-77.
-
(1999)
Blood
, vol.93
, pp. 268-277
-
-
Dai, J.1
Weinberg, R.S.2
Waxman, S.3
Jing, Y.4
-
11
-
-
0032575752
-
Mitochondria and apoptosis
-
Green DR, Reed JC. Mitochondria and apoptosis. Science 1998;281:1309-12.
-
(1998)
Science
, vol.281
, pp. 1309-1312
-
-
Green, D.R.1
Reed, J.C.2
-
12
-
-
0031037897
-
The release of cytochrome c from mitochondria: A primary site for Bcl-2 regulation of apoptosis
-
Kluck R, Bossy-Wetzel E, Green D, Newmeyer D. The release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosis. Science 1997;275:1132-6.
-
(1997)
Science
, vol.275
, pp. 1132-1136
-
-
Kluck, R.1
Bossy-Wetzel, E.2
Green, D.3
Newmeyer, D.4
-
13
-
-
0031815389
-
Inhibition of growth and induction of apoptosis in human cancer cells by tea polyphenols
-
Yang G, Liao J, Kim K, Yurkow EJ, Yang CS. Inhibition of growth and induction of apoptosis in human cancer cells by tea polyphenols. Carcinogenesis 1998;19:611-6.
-
(1998)
Carcinogenesis
, vol.19
, pp. 611-616
-
-
Yang, G.1
Liao, J.2
Kim, K.3
Yurkow, E.J.4
Yang, C.S.5
-
14
-
-
0035918278
-
Ester bound-containing tea polyphenols potently inhibit proteasome activity in vitro and in vivo
-
Nam S, Smith DM, Dou QP. Ester bound-containing tea polyphenols potently inhibit proteasome activity in vitro and in vivo. J Biol Chem 2001;276:13322-30.
-
(2001)
J Biol Chem
, vol.276
, pp. 13322-13330
-
-
Nam, S.1
Smith, D.M.2
Dou, Q.P.3
-
15
-
-
0034655603
-
Green tea polyphenol epigallocatechin-3-gallate differentially modulates nuclear factor κB in cancer cells versus normal cells
-
Ahmad N, Gupta S, Mukhtar H. Green tea polyphenol epigallocatechin-3- gallate differentially modulates nuclear factor κB in cancer cells versus normal cells. Arch Biochem Biophys 2000;376:338-46.
-
(2000)
Arch Biochem Biophys
, vol.376
, pp. 338-346
-
-
Ahmad, N.1
Gupta, S.2
Mukhtar, H.3
-
16
-
-
0034177207
-
Growth inhibition, cell-cycle dysregulation, and induction of apoptosis by green tea constituent (-)-epigallocatechin-3-gallate in androgen-sensitive and androgen-insensitive human prostate carcinoma cells
-
Gupta S, Ahmad N, Nieminen AL, Mulhtar H. Growth inhibition, cell-cycle dysregulation, and induction of apoptosis by green tea constituent (-)-epigallocatechin-3-gallate in androgen-sensitive and androgen-insensitive human prostate carcinoma cells. Toxicol Appl Pharmacol 2000;164:82-90.
-
(2000)
Toxicol Appl Pharmacol
, vol.164
, pp. 82-90
-
-
Gupta, S.1
Ahmad, N.2
Nieminen, A.L.3
Mulhtar, H.4
-
17
-
-
0032405689
-
(-)-Epigallocatechin-3-gallate inhibition of ultraviolet B-induced AP-1 activity
-
Barthelman M, Bair WB III, Stickland KK, et al. (-)-Epigallocatechin-3- gallate inhibition of ultraviolet B-induced AP-1 activity. Carcinogenesis 1998;19:2201-4.
-
(1998)
Carcinogenesis
, vol.19
, pp. 2201-2204
-
-
Barthelman, M.1
Bair III, W.B.2
Stickland, K.K.3
-
18
-
-
0034859081
-
The green tea polyphenol (-)-epigallocatechin-3-gallate blocks nuclear factor-κ B activation by inhibition I κ B kinase activity in the intestinal epithelial cell line IEC-6
-
Yang F, Oz HS, Barve S, de Villiers WJ, McClain CJ, Varilek GW. The green tea polyphenol (-)-epigallocatechin-3-gallate blocks nuclear factor-κ B activation by inhibition I κ B kinase activity in the intestinal epithelial cell line IEC-6. Mol Pharmacol 2001;60:528-33.
-
(2001)
Mol Pharmacol
, vol.60
, pp. 528-533
-
-
Yang, F.1
Oz, H.S.2
Barve, S.3
De Villiers, W.J.4
McClain, C.J.5
Varilek, G.W.6
-
19
-
-
0034733957
-
Growth factor-dependent induction of p21 (CIP1) by the green tea polyphenol, epigallocatechin gallate
-
Liberto M, Cobrinik D. Growth factor-dependent induction of p21 (CIP1) by the green tea polyphenol, epigallocatechin gallate. Cancer Lett 2000;154:151-61.
-
(2000)
Cancer Lett
, vol.154
, pp. 151-161
-
-
Liberto, M.1
Cobrinik, D.2
-
20
-
-
0035824609
-
Inhibitory mechanisms of tea polyphenols on the ultraviolet B-activated phosphatidylinositol 3-kinase-dependent pathway
-
Nomura M, Kaji A, He Z, et al. Inhibitory mechanisms of tea polyphenols on the ultraviolet B-activated phosphatidylinositol 3-kinase-dependent pathway. J Biol Chem 2001;276:46624-31.
-
(2001)
J Biol Chem
, vol.276
, pp. 46624-46631
-
-
Nomura, M.1
Kaji, A.2
He, Z.3
-
21
-
-
0034573074
-
Activation of antioxidant-response element (ARE), mitogen-activated protein kinases (MAPKs) and caspases by major green tea polyphenol components during cell survival and death
-
Chen C, Yu R, Owuor ED, Kong AN. Activation of antioxidant-response element (ARE), mitogen-activated protein kinases (MAPKs) and caspases by major green tea polyphenol components during cell survival and death. Arch Pharm Res 2000;23:605-12.
-
(2000)
Arch Pharm Res
, vol.23
, pp. 605-612
-
-
Chen, C.1
Yu, R.2
Owuor, E.D.3
Kong, A.N.4
-
22
-
-
0036624741
-
Biologic sequelae of nuclear factor-κ B blockade in multiple myeloma: Therapeutic applications
-
Mitsiades N, Mitsiades CS, Poulaki V, et al. Biologic sequelae of nuclear factor-κ B blockade in multiple myeloma: therapeutic applications. Blood 2002;99:4079-86.
-
(2002)
Blood
, vol.99
, pp. 4079-4086
-
-
Mitsiades, N.1
Mitsiades, C.S.2
Poulaki, V.3
-
23
-
-
18544367201
-
NF-κ B as a therapeutic target in multiple myeloma
-
Hideshima T, Chauhan D, Richardson P, et al. NF-κ B as a therapeutic target in multiple myeloma. J Biol Chem 2002;277:16639-47.
-
(2002)
J Biol Chem
, vol.277
, pp. 16639-16647
-
-
Hideshima, T.1
Chauhan, D.2
Richardson, P.3
-
24
-
-
0037097595
-
Apoptotic signaling induced by immunqmodulatory thalidomide analogs in human multiple myeloma cells: Therapeutic implications
-
Mitsiades N, Mitsiades CS, Poulaki V, et al. Apoptotic signaling induced by immunqmodulatory thalidomide analogs in human multiple myeloma cells: therapeutic implications. Blood 2002;99:4525-30.
-
(2002)
Blood
, vol.99
, pp. 4525-4530
-
-
Mitsiades, N.1
Mitsiades, C.S.2
Poulaki, V.3
-
25
-
-
9144220841
-
Transcriptional signature of histone deacetylase inhibition in multiple myeloma: Biological and clinical implications
-
Mitsiades CS, Mitsiades NS, McMullan CL, et al. Transcriptional signature of histone deacetylase inhibition in multiple myeloma: biological and clinical implications. Proc Natl Acad Sci U S A 2004;101:540-5.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 540-545
-
-
Mitsiades, C.S.1
Mitsiades, N.S.2
McMullan, C.L.3
-
26
-
-
15144349717
-
Cytochrome-c dependent and independent induction of apoptosis in multiple myeloma cells
-
Chauhan D, Pandey P, Ogata A, et al. Cytochrome-c dependent and independent induction of apoptosis in multiple myeloma cells. J Biol Chem 1997;272:29995-7.
-
(1997)
J Biol Chem
, vol.272
, pp. 29995-29997
-
-
Chauhan, D.1
Pandey, P.2
Ogata, A.3
-
27
-
-
0041507093
-
Apoptotic signaling in multiple myeloma: Therapeutic implications
-
Chauhan D, Hideshima T, Anderson KC. Apoptotic signaling in multiple myeloma: therapeutic implications. Int J Hematol 2002;78:114-20.
-
(2002)
Int J Hematol
, vol.78
, pp. 114-120
-
-
Chauhan, D.1
Hideshima, T.2
Anderson, K.C.3
-
28
-
-
0033198217
-
Bax translocation is a critical event in neuronal apoptosis regulation by neuroprotectants Bcl-2 and caspases
-
Putcha GV, Deshmukl M, Johnson EM, Jr. Bax translocation is a critical event in neuronal apoptosis regulation by neuroprotectants Bcl-2 and caspases. J Neurosci 1999;19:7476-85.
-
(1999)
J Neurosci
, vol.19
, pp. 7476-7485
-
-
Putcha, G.V.1
Deshmukl, M.2
Johnson Jr., E.M.3
-
29
-
-
0031984216
-
Bcl-X expression in multiple myeloma: Possible indicator of chemoresistance
-
Tu Y, Renner S, Fleishman A, et al. Bcl-X expression in multiple myeloma: possible indicator of chemoresistance. Cancer Res 1998;58:256-62.
-
(1998)
Cancer Res
, vol.58
, pp. 256-262
-
-
Tu, Y.1
Renner, S.2
Fleishman, A.3
-
30
-
-
0033179760
-
Bcl-2 family members and the mitochondria in apoptosis
-
Gross A, McDonnel JM, Korsmeyer SJ. Bcl-2 family members and the mitochondria in apoptosis. Genes Dev 1999;13:1899-911.
-
(1999)
Genes Dev
, vol.13
, pp. 1899-1911
-
-
Gross, A.1
McDonnel, J.M.2
Korsmeyer, S.J.3
-
31
-
-
0035816553
-
Apaf-1/cytochrome c-independent and Smac-dependent induction of apoptosis in multiple myeloma (MM) cells
-
Chauhan D, Hideshima T, Rosen S, Reed JC, Kharbanda S, Anderson KC. Apaf-1/cytochrome c-independent and Smac-dependent induction of apoptosis in multiple myeloma (MM) cells. J Biol Chem 2001;276:24453-6.
-
(2001)
J Biol Chem
, vol.276
, pp. 24453-24456
-
-
Chauhan, D.1
Hideshima, T.2
Rosen, S.3
Reed, J.C.4
Kharbanda, S.5
Anderson, K.C.6
-
32
-
-
0034468736
-
Role of reactive oxygen species (ROS) in apoptosis induction
-
Simon HU, Haj-Heyia A, Levi-Schaffer F. Role of reactive oxygen species (ROS) in apoptosis induction. Apoptosis 2000;5:415-8.
-
(2000)
Apoptosis
, vol.5
, pp. 415-418
-
-
Simon, H.U.1
Haj-Heyia, A.2
Levi-Schaffer, F.3
-
33
-
-
0035383778
-
Induction of mitochondrial changes in myeloma cells by imexon
-
Dvorakova K, Waltmire CN, Payne CM, Tome ME, Briehl MM, Dorr RT. Induction of mitochondrial changes in myeloma cells by imexon. Blood 2001;97:3544-51.
-
(2001)
Blood
, vol.97
, pp. 3544-3551
-
-
Dvorakova, K.1
Waltmire, C.N.2
Payne, C.M.3
Tome, M.E.4
Briehl, M.M.5
Dorr, R.T.6
-
35
-
-
4544236944
-
Generation of hydrogen peroxide primarily contributes to the induction of Fe (II)-dependent apoptosis in Jurkat cells by (-)-epigallocatechin gallate
-
Nakagawa H, Hasumi K, Woo J-T, Nagai K, Wachi M. Generation of hydrogen peroxide primarily contributes to the induction of Fe (II)-dependent apoptosis in Jurkat cells by (-)-epigallocatechin gallate. Carcinogenesis 2004;25:1567-74.
-
(2004)
Carcinogenesis
, vol.25
, pp. 1567-1574
-
-
Nakagawa, H.1
Hasumi, K.2
Woo, J.-T.3
Nagai, K.4
Wachi, M.5
-
36
-
-
19844369277
-
2-Methoxyestradiol-induced apoptosis in human leukemia cells proceeds through a reactive oxygen species and Akt-dependent process
-
Gao N, Rahmani M, Dent P, Grant S. 2-Methoxyestradiol-induced apoptosis in human leukemia cells proceeds through a reactive oxygen species and Akt-dependent process. Oncogene 2005;24:3797-809.
-
(2005)
Oncogene
, vol.24
, pp. 3797-3809
-
-
Gao, N.1
Rahmani, M.2
Dent, P.3
Grant, S.4
-
37
-
-
2542523228
-
Synergistic induction of oxidative injury and apoptosis in human multiple myeloma cells by proteasome inhibitor Bortezomib and histone deacetylase inhibitors
-
Pei X-Y, Dai Y, Grant S. Synergistic induction of oxidative injury and apoptosis in human multiple myeloma cells by proteasome inhibitor Bortezomib and histone deacetylase inhibitors. Clin Cancer Res 2004;10:3839-52.
-
(2004)
Clin Cancer Res
, vol.10
, pp. 3839-3852
-
-
Pei, X.-Y.1
Dai, Y.2
Grant, S.3
-
38
-
-
0032955284
-
Antioxidant chemistry of green tea catechins. Identification of products of the reaction of (-)-epigallocatechin gallate with peroxyl radicals
-
Valcic S, Muders A, Jacobsen NE, Liebler DC, Timmermann BN. Antioxidant chemistry of green tea catechins. Identification of products of the reaction of (-)-epigallocatechin gallate with peroxyl radicals. Chem Res Toxicol 1999;12:382-6.
-
(1999)
Chem Res Toxicol
, vol.12
, pp. 382-386
-
-
Valcic, S.1
Muders, A.2
Jacobsen, N.E.3
Liebler, D.C.4
Timmermann, B.N.5
-
40
-
-
0037115556
-
Stability, cellular uptake, biotransformation, and efflux of tea polyphenol (-)-epigallocatechin-3-gallate in HT-29 human colon adenocarcinoma cells
-
Hong J, Lu H, Meng X, Ryu JH, Hara Y, Yang CS. Stability, cellular uptake, biotransformation, and efflux of tea polyphenol (-)-epigallocatechin-3- gallate in HT-29 human colon adenocarcinoma cells. Cancer Res 2002;62:7241-6.
-
(2002)
Cancer Res
, vol.62
, pp. 7241-7246
-
-
Hong, J.1
Lu, H.2
Meng, X.3
Ryu, J.H.4
Hara, Y.5
Yang, C.S.6
-
41
-
-
0344806276
-
Prooxidant toxicity of polyphenolic antioxidants to HL-60 cells: Description of quantitative structure-activity relationship
-
Sergediene E, Jönsson K, Szymusiak H, Tyrakowska B, Rietjens IMCM, Cenas N. Prooxidant toxicity of polyphenolic antioxidants to HL-60 cells: description of quantitative structure-activity relationship. FEBS Lett 1999;462:392-6.
-
(1999)
FEBS Lett
, vol.462
, pp. 392-396
-
-
Sergediene, E.1
Jönsson, K.2
Szymusiak, H.3
Tyrakowska, B.4
Rietjens, I.M.C.M.5
Cenas, N.6
-
42
-
-
0035152982
-
Production of hydrogen peroxide and methionine sulfoxide by epigallocatechin gallate and antioxidants
-
Sakagami H, Arakawa H, Maeda M, et al. Production of hydrogen peroxide and methionine sulfoxide by epigallocatechin gallate and antioxidants. Anticancer Res 2001;21:2633-41.
-
(2001)
Anticancer Res
, vol.21
, pp. 2633-2641
-
-
Sakagami, H.1
Arakawa, H.2
Maeda, M.3
-
43
-
-
0033732496
-
2 production in transformed and non-transformed human bronchial cell lines: Possible mechanisms of cell growth inhibition and apoptosis induction
-
2 production in transformed and non-transformed human bronchial cell lines: possible mechanisms of cell growth inhibition and apoptosis induction. Carcinogenesis 2000;21:2035-9.
-
(2000)
Carcinogenesis
, vol.21
, pp. 2035-2039
-
-
Yang, G.Y.1
Liao, J.2
Li, C.3
-
44
-
-
0033568238
-
Arsenic trioxide selectively induces acute promyelocytic leukemia cell apoptosis via a hydrogen peroxide-dependent pathway
-
Jing Y, Dai J, Chalmens-Redman RME, Tatton WG, Waxman S. Arsenic trioxide selectively induces acute promyelocytic leukemia cell apoptosis via a hydrogen peroxide-dependent pathway. Blood 1999;94:2102-11.
-
(1999)
Blood
, vol.94
, pp. 2102-2111
-
-
Jing, Y.1
Dai, J.2
Chalmens-Redman, R.M.E.3
Tatton, W.G.4
Waxman, S.5
-
45
-
-
0031657760
-
Involvement of reactive oxygen species and caspase 3 activation in arsenite-induced apoptosis
-
Chen Y-C, Lin-Shiau SY, Lin J-K. Involvement of reactive oxygen species and caspase 3 activation in arsenite-induced apoptosis. J Cell Physiol 1998;177:324-33.
-
(1998)
J Cell Physiol
, vol.177
, pp. 324-333
-
-
Chen, Y.-C.1
Lin-Shiau, S.Y.2
Lin, J.-K.3
-
46
-
-
0034947164
-
Catechin metabolism: Glutathione conjugate formation catalyzed by tyrosinase, peroxidase, and cytochrome P450
-
Moridani MY, Scobie H, Salehi P, O'Brien PJ. Catechin metabolism: glutathione conjugate formation catalyzed by tyrosinase, peroxidase, and cytochrome P450. Chem Res Toxicol 2001;14:841-8.
-
(2001)
Chem Res Toxicol
, vol.14
, pp. 841-848
-
-
Moridani, M.Y.1
Scobie, H.2
Salehi, P.3
O'Brien, P.J.4
-
47
-
-
0035868975
-
Phase I trial of oral green tea extract in adult patients with solid tumors
-
Pisters AMW, Newman RA, Coldman B, et al. Phase I trial of oral green tea extract in adult patients with solid tumors. J Clin Oncol 2001;19:1830-8.
-
(2001)
J Clin Oncol
, vol.19
, pp. 1830-1838
-
-
Pisters, A.M.W.1
Newman, R.A.2
Coldman, B.3
-
48
-
-
0035682310
-
Inhibition of tumour invasion and angiogenesis by epigallocatechin gallate (EGCG), a major component of green tea
-
Jung YD, Ellis LM. Inhibition of tumour invasion and angiogenesis by epigallocatechin gallate (EGCG), a major component of green tea. Int J Exp Pathol 2001;82:309-16.
-
(2001)
Int J Exp Pathol
, vol.82
, pp. 309-316
-
-
Jung, Y.D.1
Ellis, L.M.2
-
49
-
-
0033859756
-
Inhibition of angiogenesis and induction of endothelial and tumor cell apoptosis by green tea in animal models of human high-grade non-Hodgkin's lymphoma
-
Bertolini F, Fusetti L, Cinieri S, Martinelli G, Pruneri G. Inhibition of angiogenesis and induction of endothelial and tumor cell apoptosis by green tea in animal models of human high-grade non-Hodgkin's lymphoma. Leukemia 2000;14:1477-82.
-
(2000)
Leukemia
, vol.14
, pp. 1477-1482
-
-
Bertolini, F.1
Fusetti, L.2
Cinieri, S.3
Martinelli, G.4
Pruneri, G.5
-
50
-
-
4344605629
-
Effect of EGCG, a major component of green tea, on the expression of Ets-1, c-Fos, and c-Jun during angiogenesis in vivo
-
Lai HC, Chao WT, Chen YT, Yang VC. Effect of EGCG, a major component of green tea, on the expression of Ets-1, c-Fos, and c-Jun during angiogenesis in vivo. Cancer Lett 2004;213:181-8.
-
(2004)
Cancer Lett
, vol.213
, pp. 181-188
-
-
Lai, H.C.1
Chao, W.T.2
Chen, Y.T.3
Yang, V.C.4
|