Multifaceted roles of alkyltransferase and related proteins in DNA repair, DNA damage, resistance to chemotherapy, and research tools

Chemical Research in Toxicology

Volumn 24, Issue 5, 2011, Pages 618-639

  Pegg, Anthony E ^a  

^a PENN STATE MILTON S HERSHEY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 O METHYLTHYMINE; 6 O ALKYLGUANINE DNA ALKYLTRANSFERASE; 6 O BENZYLGUANINE; ALKANE DERIVATIVE; ALKYLATING AGENT; ANTINEOPLASTIC AGENT; ELECTROPHILE; HISTONE; HYBRID PROTEIN; METHYLNITRONITROSOGUANIDINE; NITRIC OXIDE; NITROSO DERIVATIVE; PROTEIN TAG;

AMINO ACID SEQUENCE; CANCER CHEMOTHERAPY; CANCER RESISTANCE; CARCINOGENESIS; CHEMICAL REACTION; CYTOTOXICITY; DNA ALKYLATION; DNA CROSS LINKING; DNA DAMAGE; DNA POLYMORPHISM; DNA REPAIR; ENZYME ACTIVITY; ENZYME DEGRADATION; ENZYME INACTIVATION; ENZYME STRUCTURE; GENE MUTATION; GENETIC TRANSCRIPTION; HUMAN; MAMMAL CELL; MUTAGENESIS; NONHUMAN; PROTEIN FUNCTION; PROTEIN VARIANT; REVIEW; TRANSCRIPTION REGULATION;

AMINO ACID SEQUENCE; ANIMALS; DNA; DNA DAMAGE; DNA REPAIR; DRUG RESISTANCE, NEOPLASM; HUMANS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; NEOPLASMS; O(6)-METHYLGUANINE-DNA METHYLTRANSFERASE; SEQUENCE ALIGNMENT;

EID: 79956084544     PISSN: 0893228X     EISSN: 15205010     Source Type: Journal    
DOI: 10.1021/tx200031q     Document Type: Review

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