Structural basis of O6-alkylguanine recognition by a bacterial alkyltransferase-like DNA repair protein

Journal of Biological Chemistry

Volumn 285, Issue 18, 2010, Pages 13736-13741

  Aramini, James M ^a,b   Tubbs, Julie L ^c   Kanugula, Sreenivas ^c   Rossi, Paolo ^a,b   Ertekin, Asli ^a,b   Maglaqui, Melissa ^a,b   Hamilton, Keith ^a,b   Ciccosanti, Colleen T ^a,b   Jiang, Mei ^a,b   Xiao, Rong ^a,b   Soong, Ta Tsen ^b,e   Rost, Burkhard ^b,e   Acton, Thomas B ^a,b   Everett, John K ^a,b   Pegg, Anthony E ^d   Tainer, John A ^c,f   Montelione, Gaetano T ^a,b,g  

^a RUTGERS UNIVERSITY   (United States)

^b Northeast Structural Genomics Consortium ^*  (United States)

^c SCRIPPS RESEARCH INSTITUTE   (United States)

^d PENN STATE COLLEGE OF MEDICINE   (United States)

^e Och Spine at New York Presbyterian Hospitals   (United States)

^f LAWRENCE BERKELEY NATIONAL LABORATORY   (United States)

^g RUTGERS ROBERT WOOD JOHNSON MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALKYLTRANSFERASE; CONFORMATIONAL PLASTICITY; CONSERVED RESIDUES; DNA REPAIR; DNA REPAIR PROTEINS; NMR RELAXATION; NUCLEOTIDE EXCISION REPAIR; STRUCTURAL BASIS; VIBRIO PARAHAEMOLYTICUS;

BACTERIOLOGY; DNA; PROTEINS; REPAIR;

GENES;

6 O ALKYLGUANINE DNA ALKYLTRANSFERASE; ALKYLTRANSFERASE LIKE PROTEIN; ARGININE; BACTERIAL PROTEIN; GUANINE; TYROSINE; UNCLASSIFIED DRUG; DNA; DRUG DERIVATIVE; O (6) METHYLGUANINE; O-(6)-METHYLGUANINE; TRANSFERASE;

AMINO ACID SEQUENCE; ARTICLE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; DNA ALKYLATION; DNA REPAIR; MOLECULAR RECOGNITION; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; PROTEIN DNA BINDING; PROTEIN FOLDING; PROTEIN STRUCTURE; VIBRIO PARAHAEMOLYTICUS; AMINO ACID SUBSTITUTION; CHEMISTRY; ENZYMOLOGY; GENETICS; HUMAN; METABOLISM; MISSENSE MUTATION; PHYSIOLOGY;

BACTERIA (MICROORGANISMS); VIBRIO PARAHAEMOLYTICUS;

ALKYL AND ARYL TRANSFERASES; AMINO ACID SUBSTITUTION; DNA; DNA REPAIR; GUANINE; HUMANS; MUTATION, MISSENSE; PROTEIN FOLDING; VIBRIO PARAHAEMOLYTICUS;

EID: 77951582198     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.093591     Document Type: Article

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