Characterization of a Mutagenic DNA Adduct Formed from 1,2-Dibromoethane by O6-Alkylguanine-DNA Alkyltransferase

Journal of Biological Chemistry

Volumn 279, Issue 6, 2004, Pages 4250-4259

  Liu, Liping ^a,c   Hachey, David L ^b   Valadez, Gerardo ^b   Williams, Kevin M ^b,d   Guengerich, F Peter ^b   Loktionova, Natalia A ^a   Kanugula, Sreenivas ^a   Pegg, Anthony E ^a  

^a PENN STATE COLLEGE OF MEDICINE   (United States)

^b VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

^d WESTERN KENTUCKY UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALKYLATION; CHROMATOGRAPHIC ANALYSIS; CROSSLINKING; DNA; ENZYMES; ESCHERICHIA COLI; MASS SPECTROMETRY; MUTAGENESIS;

CYSTEINE ACCEPTOR SITE; DEPURINATION;

BIOCHEMISTRY;

1,2 DIBROMOETHANE; 6 O ALKYLGUANINE DNA ALKYLTRANSFERASE;

ANIMAL CELL; ARTICLE; COMPLEX FORMATION; COVALENT BOND; DNA ADDUCT; DNA ALKYLATION; DNA REPAIR; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME ANALYSIS; GENE; GENE MUTATION; MASS SPECTROMETRY; MUTAGENICITY; NONHUMAN; PEPTIDE SYNTHESIS; PRIORITY JOURNAL; PROTEIN SYNTHESIS; RPOB GENE;

ANIMALS; CATTLE; DNA ADDUCTS; ETHYLENE DIBROMIDE; HUMANS; MOLECULAR STRUCTURE; MUTAGENS; O(6)-METHYLGUANINE-DNA METHYLTRANSFERASE; RECOMBINANT PROTEINS; SALMONELLA TYPHIMURIUM; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION;

ANIMALIA; ESCHERICHIA COLI;

EID: 1042266666     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M311105200     Document Type: Article

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