Novel human DNA alkyltransferases obtained by random substitution and genetic selection in bacteria

Proceedings of the National Academy of Sciences of the United States of America

Volumn 93, Issue 12, 1996, Pages 6124-6128

  Christians, Fred C ^a   Loeb, Lawrence A ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

Author keywords

alkylating agents; gene therapy; hematopoietic stem cells; O6 methylguanine DNA methyltransferase; random mutagenesis

Indexed keywords

ALKYLATING AGENT; CYSTEINE; METHYLATED DNA PROTEIN CYSTEINE METHYLTRANSFERASE; METHYLNITRONITROSOGUANIDINE; MUTANT PROTEIN;

ARTICLE; CARCINOGENICITY; CONTROLLED STUDY; CYTOTOXICITY; DNA ALKYLATION; DNA REPAIR; ESCHERICHIA COLI; GENE MUTATION; GENE TRANSFER; HEMATOPOIETIC STEM CELL; MUTAGENICITY; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL;

AMINO ACID SEQUENCE; BASE SEQUENCE; CLONING, MOLECULAR; DNA, COMPLEMENTARY; ESCHERICHIA COLI; HUMANS; METHYLTRANSFERASES; MOLECULAR SEQUENCE DATA; MUTAGENESIS; O(6)-METHYLGUANINE-DNA METHYLTRANSFERASE;

EID: 0029929724     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.93.12.6124     Document Type: Article

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