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Volumn 24, Issue 4, 2003, Pages 625-635

Variability and regulation of O6-alkylguanine-DNA alkyltransferase

Author keywords

[No Author keywords available]

Indexed keywords

6 O ALKYLGUANINE DNA ALKYLTRANSFERASE; 6 O ALKYLGUANINE DNA ALKYLTRANSFERASE INHIBITOR; 6 O BENZYLGUANINE; ALKYLATING AGENT; ANTINEOPLASTIC AGENT; CARMUSTINE; DEXAMETHASONE; TEMOZOLOMIDE; TRANSCRIPTION FACTOR AP 1; DNA; METHYLATED DNA PROTEIN CYSTEINE METHYLTRANSFERASE; TRANSCRIPTION FACTOR;

EID: 0038055835     PISSN: 01433334     EISSN: None     Source Type: Journal    
DOI: 10.1093/carcin/bgg005     Document Type: Review
Times cited : (181)

References (143)
  • 1
    • 0030611736 scopus 로고    scopus 로고
    • 6-methylguanine-DNA methyltransferase expression
    • 6-methylguanine-DNA methyltransferase expression. Pharmacol. Ther., 74, 285-297.
    • (1997) Pharmacol. Ther. , vol.74 , pp. 285-297
    • Pieper, R.O.1
  • 2
    • 0034028030 scopus 로고    scopus 로고
    • 6-alkylguanine by alkyltransferases
    • 6-alkylguanine by alkyltransferases. Mutat. Res., 462, 83-100.
    • (2000) Mutat. Res. , vol.462 , pp. 83-100
    • Pegg, A.E.1
  • 4
    • 0036006173 scopus 로고    scopus 로고
    • 6-Alkylguanine-DNA alkyltransferase: Role in carcinogenesis and chemotherapy
    • 6-Alkylguanine-DNA alkyltransferase: role in carcinogenesis and chemotherapy. Bioessays, 24, 255-266.
    • (2002) Bioessays , vol.24 , pp. 255-266
    • Margison, G.P.1    Santibáñez Koref, M.F.2
  • 5
    • 0031589755 scopus 로고    scopus 로고
    • + and methylation-tolerant mismatch repair compromised cells: Facts and models
    • + and methylation-tolerant mismatch repair compromised cells: facts and models. Mutat. Res., 381, 227-241.
    • (1997) Mutat. Res. , vol.381 , pp. 227-241
    • Kaina, B.1    Ziouta, A.2    Ochs, K.3    Coquerelle, T.4
  • 6
    • 0036709625 scopus 로고    scopus 로고
    • 6-methylguanine DNA-methyltransferase in other organisms
    • 6-methylguanine DNA-methyltransferase in other organisms. Mutat. Res., 512, 67-84.
    • (2002) Mutat. Res. , vol.512 , pp. 67-84
    • Kleibl, K.1
  • 7
    • 0035175762 scopus 로고    scopus 로고
    • Novel DNA repair alkyltransferase from Caenorhabditis elegans
    • Kanugula,S. and Pegg,A.E. (2001) Novel DNA repair alkyltransferase from Caenorhabditis elegans. Environ. Mol. Mutagen., 38, 235-243.
    • (2001) Environ. Mol. Mutagen. , vol.38 , pp. 235-243
    • Kanugula, S.1    Pegg, A.E.2
  • 9
    • 0029152241 scopus 로고
    • 6-methylguanine DNA methyltransferase (MGMT) expression in Mer+ human tumor cells
    • 6-methylguanine DNA methyltransferase (MGMT) expression in Mer+ human tumor cells. Carcinogenesis, 16, 2255-2257.
    • (1995) Carcinogenesis , vol.16 , pp. 2255-2257
    • Kroes, R.A.1    Erickson, L.C.2
  • 10
    • 0025767132 scopus 로고
    • 6-methylguanine-DNA methyltransferase in mammalian cells by DNA-damaging treatments
    • 6-methylguanine-DNA methyltransferase in mammalian cells by DNA-damaging treatments. Mol. Cell Biol., 11, 4660-4668.
    • (1991) Mol. Cell Biol. , vol.11 , pp. 4660-4668
    • Fritz, G.1    Tano, K.2    Mitra, S.3    Kaina, B.4
  • 13
    • 0030608633 scopus 로고    scopus 로고
    • 6-Benzylguanine and its role in chemotherapy
    • 6-Benzylguanine and its role in chemotherapy. Clin. Cancer Res., 3, 837-847.
    • (1997) Clin. Cancer Res. , vol.3 , pp. 837-847
    • Dolan, M.E.1    Pegg, A.E.2
  • 14
    • 0034813581 scopus 로고    scopus 로고
    • 6-methylguanine-DNA methyltransferase is a negative regulator of estrogen receptor-mediated transcription upon alkylation DNA damage
    • 6-methylguanine-DNA methyltransferase is a negative regulator of estrogen receptor-mediated transcription upon alkylation DNA damage. Mol. Cell Biol., 21, 7105-7114.
    • (2001) Mol. Cell Biol. , vol.21 , pp. 7105-7114
    • Teo, A.K.1    Oh, H.K.2    Ali, R.B.3    Li, B.F.4
  • 20
    • 0028904619 scopus 로고
    • Transgenic expression of human MGMT protects against azoxymethane-induced aberrant crypt foci and G to A mutations in the K-ras oncogene of mouse colon
    • Zaidi,N.H., Pretlow,T.P., O'Riordan,M.A., Dumenco,L.L., Allay,E. and Gerson,S.L. (1995) Transgenic expression of human MGMT protects against azoxymethane-induced aberrant crypt foci and G to A mutations in the K-ras oncogene of mouse colon. Carcinogenesis, 16, 451-456.
    • (1995) Carcinogenesis , vol.16 , pp. 451-456
    • Zaidi, N.H.1    Pretlow, T.P.2    O'Riordan, M.A.3    Dumenco, L.L.4    Allay, E.5    Gerson, S.L.6
  • 21
    • 0029901710 scopus 로고    scopus 로고
    • 6-methylguanine-DNA methyltransferase (MGMT) in transgenic mice protects against tumor initiation in two-stage skin carcinogenesis
    • 6-methylguanine-DNA methyltransferase (MGMT) in transgenic mice protects against tumor initiation in two-stage skin carcinogenesis. Cancer Res., 56, 3244-3249.
    • (1996) Cancer Res. , vol.56 , pp. 3244-3249
    • Becker, K.1    Dosch, J.2    Gregel, C.M.3    Martin, B.A.4    Kaina, B.5
  • 22
    • 0030749230 scopus 로고    scopus 로고
    • 6-methylguanine-DNA methyltransferase protects against skin tumor formation induced by antineoplastic chloroethylnitrosourea
    • 6-methylguanine-DNA methyltransferase protects against skin tumor formation induced by antineoplastic chloroethylnitrosourea. Cancer Res., 57, 3335-3338.
    • (1997) Cancer Res. , vol.57 , pp. 3335-3338
    • Becker, K.1    Gregel, C.M.2    Kaina, B.3
  • 23
    • 0032979605 scopus 로고    scopus 로고
    • 6-alkylguanine-DNA alkyltransferases are hypersensitive to dibromoalkanes
    • 6-alkylguanine-DNA alkyltransferases are hypersensitive to dibromoalkanes. Chem. Res. Toxicol., 12, 544-551.
    • (1999) Chem. Res. Toxicol. , vol.12 , pp. 544-551
    • Abril, N.1    Margison, G.P.2
  • 24
    • 0034691834 scopus 로고    scopus 로고
    • 6-alkylguanine-DNA alkyltransferase in promoting 1,2-dibromoethane-induced genotoxicity in Escherichia coli
    • 6-alkylguanine-DNA alkyltransferase in promoting 1,2-dibromoethane-induced genotoxicity in Escherichia coli. Mutat. Res., 452, 1-10.
    • (2000) Mutat. Res. , vol.452 , pp. 1-10
    • Liu, H.1    Xu-Welliver, M.2    Pegg, A.E.3
  • 25
    • 0031408141 scopus 로고    scopus 로고
    • Bacterial and mammalian DNA alkyltransferases sensitize Escherichia coli to the lethal and mutagenic effects of dibromoalkanes
    • Abril,N., Luque-Romero,F.L., Prieto-Alamo,M.J., Rafferty,J.A., Margison,G.P. and Pueyo,C. (1997) Bacterial and mammalian DNA alkyltransferases sensitize Escherichia coli to the lethal and mutagenic effects of dibromoalkanes. Carcinogenesis, 18, 1883-1888.
    • (1997) Carcinogenesis , vol.18 , pp. 1883-1888
    • Abril, N.1    Luque-Romero, F.L.2    Prieto-Alamo, M.J.3    Rafferty, J.A.4    Margison, G.P.5    Pueyo, C.6
  • 28
    • 0032552637 scopus 로고    scopus 로고
    • DNA adducts in humans after exposure to methylating agents
    • Kyrtopoulos,S.A. (1998) DNA adducts in humans after exposure to methylating agents. Mutat. Res., 405, 135-143.
    • (1998) Mutat. Res. , vol.405 , pp. 135-143
    • Kyrtopoulos, S.A.1
  • 29
    • 0031426032 scopus 로고    scopus 로고
    • 6-alkylguanine-DNA alkyltransferase deficient cells
    • 6-alkylguanine-DNA alkyltransferase deficient cells. Carcinogenesis, 18, 1561-1567.
    • (1997) Carcinogenesis , vol.18 , pp. 1561-1567
    • Sedgwick, B.1
  • 31
    • 0020341190 scopus 로고
    • Nonenzymatic methylation of DNA by the intracellular methyl group donor S-adenosyl-L-methionine is a potentially mutagenic reaction
    • Rydberg,B. and Lindahl,T. (1982) Nonenzymatic methylation of DNA by the intracellular methyl group donor S-adenosyl-L-methionine is a potentially mutagenic reaction. EMBO J., 1, 211-216.
    • (1982) EMBO J. , vol.1 , pp. 211-216
    • Rydberg, B.1    Lindahl, T.2
  • 32
    • 0020324376 scopus 로고
    • Nonenzymatic methylation of DNA by S-adenosylmethionine in vitro
    • Barrows,L.R. and Magee,P.N. (1982) Nonenzymatic methylation of DNA by S-adenosylmethionine in vitro. Carcinogenesis, 3, 349-351.
    • (1982) Carcinogenesis , vol.3 , pp. 349-351
    • Barrows, L.R.1    Magee, P.N.2
  • 33
    • 0021680014 scopus 로고
    • Relevance of nitrosamines to human cancer
    • Bartsch,H. and Montesano,R. (1984) Relevance of nitrosamines to human cancer. Carcinogenesis, 5, 1381-1393.
    • (1984) Carcinogenesis , vol.5 , pp. 1381-1393
    • Bartsch, H.1    Montesano, R.2
  • 36
    • 0019395086 scopus 로고
    • 6-methylguanine from DNA of normal and xeroderma pigmentosum-derived lymphoblastoid lines
    • 6-methylguanine from DNA of normal and xeroderma pigmentosum-derived lymphoblastoid lines. Nature, 289, 417-420.
    • (1981) Nature , vol.289 , pp. 417-420
    • Sklar, R.1    Strauss, B.2
  • 37
    • 0025194777 scopus 로고
    • 6-methylguanine-DNA methyltransferase (MGMT) activity in mammalian cells: A pre-molecular view
    • 6-methylguanine-DNA methyltransferase (MGMT) activity in mammalian cells: a pre-molecular view. Mutat. Res., 233, 139-150.
    • (1990) Mutat. Res. , vol.233 , pp. 139-150
    • Strauss, B.S.1
  • 38
    • 0024474023 scopus 로고
    • 6-alkylguanine-DNA alkyltransferase activity in peripheral blood lymphocytes: Relationship between this activity in lymphocytes and in lymphoblastoid lines from normal controls and from patients with Hodgkin's disease or non-Hodgkin's lymphoma
    • 6-alkylguanine-DNA alkyltransferase activity in peripheral blood lymphocytes: relationship between this activity in lymphocytes and in lymphoblastoid lines from normal controls and from patients with Hodgkin's disease or non-Hodgkin's lymphoma. Cancer Res., 49, 5339-5344.
    • (1989) Cancer Res. , vol.49 , pp. 5339-5344
    • Sagher, D.1    Karrison, T.2    Schwartz, J.L.3    Larson, R.A.4    Strauss, B.5
  • 39
    • 0024469972 scopus 로고
    • Predominance of Mex+ cells in newly-established human lymphoblastoid cell lines
    • Arita,I., Tachibana,A., Takebe,H. and Tatsumi,K. (1989) Predominance of Mex+ cells in newly-established human lymphoblastoid cell lines. Carcinogenesis, 10, 2067-2073.
    • (1989) Carcinogenesis , vol.10 , pp. 2067-2073
    • Arita, I.1    Tachibana, A.2    Takebe, H.3    Tatsumi, K.4
  • 45
    • 0026609497 scopus 로고
    • 6-methylguanine and the stimulation of DNA synthesis and growth of cultured chick hepatocytes
    • 6-methylguanine and the stimulation of DNA synthesis and growth of cultured chick hepatocytes. Carcinogenesis, 13, 33-39.
    • (1992) Carcinogenesis , vol.13 , pp. 33-39
    • Dutta-Choudhury, T.A.1    Couri, D.2    Stephens, R.E.3
  • 46
    • 0022269503 scopus 로고
    • 6-Methylguanine repair of methylated DNA in vitro: Cell cycle-dependence of rat liver methyltransferase activity
    • 6-Methylguanine repair of methylated DNA in vitro: cell cycle-dependence of rat liver methyltransferase activity. J. Cancer Res. Clin. Oncol., 110, 98-102.
    • (1985) J. Cancer Res. Clin. Oncol. , vol.110 , pp. 98-102
    • Schuster, C.1    Rode, G.2    Rabes, H.M.3
  • 47
    • 0034665972 scopus 로고    scopus 로고
    • Promoter structure and cell cycle dependent expression of the human methylpurine-DNA glycosylase gene
    • Bouziane,M., Miao,F., Bates,S.E., Somsouk,L., Sang,B.C., Denissenko,M. and O'Connor,T.R. (2000) Promoter structure and cell cycle dependent expression of the human methylpurine-DNA glycosylase gene. Mutat. Res., 461, 15-29.
    • (2000) Mutat. Res. , vol.461 , pp. 15-29
    • Bouziane, M.1    Miao, F.2    Bates, S.E.3    Somsouk, L.4    Sang, B.C.5    Denissenko, M.6    O'Connor, T.R.7
  • 48
    • 0033178297 scopus 로고    scopus 로고
    • Confluence-induced alterations in CpG island methylation in cultured normal human fibroblasts
    • Pieper,R.O., Lester,K.A. and Fanton,C.P. (1999) Confluence-induced alterations in CpG island methylation in cultured normal human fibroblasts. Nucleic Acids Res., 27, 3229-3235.
    • (1999) Nucleic Acids Res. , vol.27 , pp. 3229-3235
    • Pieper, R.O.1    Lester, K.A.2    Fanton, C.P.3
  • 50
    • 0022931463 scopus 로고
    • 6-alkylguanine-DNA alkyltransferase activity based on cellular DNA content in human, rat and mouse tissues
    • 6-alkylguanine-DNA alkyltransferase activity based on cellular DNA content in human, rat and mouse tissues. Carcinogenesis, 7, 745-749.
    • (1986) Carcinogenesis , vol.7 , pp. 745-749
    • Gerson, S.L.1    Trey, J.E.2    Miller, K.3    Berger, N.A.4
  • 54
    • 0027336954 scopus 로고
    • 6-methylguanine-DNA methyltransferase activity in brain tumors and adjacent normal brain
    • 6-methylguanine-DNA methyltransferase activity in brain tumors and adjacent normal brain. Cancer Res., 53, 3416-3420.
    • (1993) Cancer Res. , vol.53 , pp. 3416-3420
    • Silber, J.R.1    Mueller, B.A.2    Ewers, T.G.3    Berger, M.S.4
  • 55
    • 0032766511 scopus 로고    scopus 로고
    • 6-methylguanine-DNA methyltransferase in relation to p53 status and therapeutic response in ovarian cancer
    • 6-methylguanine-DNA methyltransferase in relation to p53 status and therapeutic response in ovarian cancer. Int. J. Cancer, 84, 388-395.
    • (1999) Int. J. Cancer , vol.84 , pp. 388-395
    • Hengstler, J.G.1    Tanner, B.2    Moller, L.3    Meinert, R.4    Kaina, B.5
  • 59
    • 0031283135 scopus 로고    scopus 로고
    • 6-alkylguanine-DNA alkyltransferase gene is elevated in human breast tumor cells
    • 6-alkylguanine-DNA alkyltransferase gene is elevated in human breast tumor cells. Anticancer Res., 17, 4311-4315.
    • (1997) Anticancer Res. , vol.17 , pp. 4311-4315
    • Wani, G.1    D'Ambrosio, S.M.2
  • 61
    • 0030068736 scopus 로고    scopus 로고
    • 6-methylguanine-DNA methyltransferase in human tumor and corresponding normal tissue
    • 6-methylguanine-DNA methyltransferase in human tumor and corresponding normal tissue. Cancer Detect. Prev., 20, 130-136.
    • (1996) Cancer Detect. Prev. , vol.20 , pp. 130-136
    • Preuss, I.1    Haas, S.2    Eichhorn, U.3
  • 67
    • 0031597371 scopus 로고    scopus 로고
    • 6-methylguanine-DNA methyltransferase in pretreatment tumour biopsies as a predictor of response to temozolomide in melanoma
    • 6-methylguanine-DNA methyltransferase in pretreatment tumour biopsies as a predictor of response to temozolomide in melanoma. Br. J. Cancer, 78, 1199-1202.
    • (1998) Br. J. Cancer , vol.78 , pp. 1199-1202
    • Middleton, M.R.1    Lunn, J.M.2    Morris, C.3
  • 70
    • 0008881320 scopus 로고    scopus 로고
    • 6-alkylguanine-DNA-alkyltransferase in hepatitis B cirrhotic human liver: A potential cofactor in the development of hepatocellular carcinoma
    • 6-alkylguanine-DNA-alkyltransferase in hepatitis B cirrhotic human liver: a potential cofactor in the development of hepatocellular carcinoma. Hepatology, 24, 987-990.
    • (1996) Hepatology , vol.24 , pp. 987-990
    • Lee, S.M.1    Portmann, B.C.2    Margison, G.P.3
  • 71
    • 0005726065 scopus 로고
    • 6-alkylguanine in mammalian systems
    • Seeberg,E. and Kleepe,K. (eds), Plenum Press, New York, London
    • 6-alkylguanine in mammalian systems. In Seeberg,E. and Kleepe,K. (eds), Chromosome Damage and Repair. Plenum Press, New York, London.
    • (1981) Chromosome Damage and Repair
    • O'Connor, P.J.1    Margisson, G.P.2
  • 73
    • 0029803785 scopus 로고    scopus 로고
    • Induction of the alkyltransferase (MGMT) gene by DNA damaging agents and the glucocorticoid dexamethasone and comparison with the response of base excision repair genes
    • Grombacher,T., Mitra,S. and Kaina,B. (1996) Induction of the alkyltransferase (MGMT) gene by DNA damaging agents and the glucocorticoid dexamethasone and comparison with the response of base excision repair genes. Carcinogenesis, 17, 2329-2336.
    • (1996) Carcinogenesis , vol.17 , pp. 2329-2336
    • Grombacher, T.1    Mitra, S.2    Kaina, B.3
  • 76
    • 0023818419 scopus 로고
    • 6-methylguanine-DNA methyltransferase in C3H/10T1/2 cells by X-rays is inhibited by nitrogen
    • 6-methylguanine-DNA methyltransferase in C3H/10T1/2 cells by X-rays is inhibited by nitrogen. Carcinogenesis, 9, 679-681.
    • (1988) Carcinogenesis , vol.9 , pp. 679-681
    • von Hofe, E.1    Kennedy, A.R.2
  • 77
    • 0028859644 scopus 로고
    • 6-methylguanine-DNA methyltransferase and N-methylpurine-DNA glycosylase in rat liver cells exhibiting different status of differentiation
    • 6-methylguanine-DNA methyltransferase and N-methylpurine-DNA glycosylase in rat liver cells exhibiting different status of differentiation. Biochim. Biophys. Acta, 1270, 63-72.
    • (1995) Biochim. Biophys. Acta , vol.1270 , pp. 63-72
    • Grombacher, T.1    Kaina, B.2
  • 78
    • 0026493772 scopus 로고
    • 6-methylguanine-DNA methyltransferase mRNA in rat hepatoma cells
    • 6-methylguanine-DNA methyltransferase mRNA in rat hepatoma cells. Biochim. Biophys. Acta, 1171, 35-40.
    • (1992) Biochim. Biophys. Acta , vol.1171 , pp. 35-40
    • Fritz, G.1    Kaina, B.2
  • 79
    • 0025039144 scopus 로고
    • Induction of proteins involved in the repair of alkylated bases in mammalian cells by DNA-damaging agents
    • Laval,F. (1990) Induction of proteins involved in the repair of alkylated bases in mammalian cells by DNA-damaging agents. Mutat. Res., 233, 211-218.
    • (1990) Mutat. Res. , vol.233 , pp. 211-218
    • Laval, F.1
  • 80
    • 0024450651 scopus 로고
    • 6-methylguanine-DNA-methyltransferase activity in a rat hepatoma cell line by poly (ADP-ribose) synthesis inhibitors
    • 6-methylguanine-DNA-methyltransferase activity in a rat hepatoma cell line by poly (ADP-ribose) synthesis inhibitors. Biochem. Biophys. Res. Commun., 163, 599-604.
    • (1989) Biochem. Biophys. Res. Commun. , vol.163 , pp. 599-604
    • Lefebvre, P.1    Laval, F.2
  • 82
    • 0026616951 scopus 로고
    • 6-methylguanine-DNA methyltransferase and uracil-DNA glycosylase in human placentae from smokers and non-smokers
    • 6-methylguanine-DNA methyltransferase and uracil-DNA glycosylase in human placentae from smokers and non-smokers. Carcinogenesis, 13, 1769-1773.
    • (1992) Carcinogenesis , vol.13 , pp. 1769-1773
    • Slupphaug, G.1    Lettrem, I.2    Myrnes, B.3    Krokan, H.E.4
  • 83
    • 0031878857 scopus 로고    scopus 로고
    • 6-methylguanine-DNA methyltransferase expression in human lung carcinomas
    • 6-methylguanine-DNA methyltransferase expression in human lung carcinomas. Carcinogenesis, 19, 1247-1250.
    • (1998) Carcinogenesis , vol.19 , pp. 1247-1250
    • Mattern, J.1    Koomagi, R.2    Volm, M.3
  • 84
  • 87
    • 0028805169 scopus 로고
    • 6-methylguanine-DNA methyltransferase gene in young patients with adult type cancers and functional assay
    • 6-methylguanine-DNA methyltransferase gene in young patients with adult type cancers and functional assay. Carcinogenesis, 16, 2441-2445.
    • (1995) Carcinogenesis , vol.16 , pp. 2441-2445
    • Imai, Y.1    Oda, H.2    Nakatsuru, Y.3    Ishikawa, T.4
  • 92
    • 0033584567 scopus 로고    scopus 로고
    • 6-methylguanine-DNA methyltransferase (MGMT) and N-methylpurine-DNA glycosylase (MPG) in lung cancer patients from Poland
    • 6-methylguanine-DNA methyltransferase (MGMT) and N-methylpurine-DNA glycosylase (MPG) in lung cancer patients from Poland. Hum. Mutat., 14, 269-270.
    • (1999) Hum. Mutat. , vol.14 , pp. 269-270
    • Rusin, M.1    Samojedny, A.2    Harris, C.C.3    Chorazy, M.4
  • 97
    • 0030611199 scopus 로고    scopus 로고
    • 6-methylguanine-DNA methyltransferase enhancer binding protein in DNA repair-deficient human cells
    • 6-methylguanine-DNA methyltransferase enhancer binding protein in DNA repair-deficient human cells. Proc. Natl Acad. Sci. USA, 94, 4348-4353.
    • (1997) Proc. Natl Acad. Sci. USA , vol.94 , pp. 4348-4353
    • Chen, F.Y.1    Harris, L.C.2    Remack, J.S.3    Brent, T.P.4
  • 99
    • 0032552021 scopus 로고    scopus 로고
    • 6-methylguanine-DNA methyltransferase (MGMT) by DNA damaging agents
    • 6-methylguanine-DNA methyltransferase (MGMT) by DNA damaging agents. Oncogene, 17, 845-851.
    • (1998) Oncogene , vol.17 , pp. 845-851
    • Grombacher, T.1    Eichhorn, U.2    Kaina, B.3
  • 102
    • 0034602378 scopus 로고    scopus 로고
    • 6-methylguanine-DNA methyltransferase gene by transcriptional coactivators cAMP response element-binding protein-binding protein and p300
    • 6-methylguanine-DNA methyltransferase gene by transcriptional coactivators cAMP response element-binding protein-binding protein and p300. J. Biol. Chem., 275, 34197-34204.
    • (2000) J. Biol. Chem. , vol.275 , pp. 34197-34204
    • Bhakat, K.K.1    Mitra, S.2
  • 103
    • 0030879709 scopus 로고    scopus 로고
    • 6-methylguanine DNA methyltransferase gene is associated with the loss of nucleosome-like positioning
    • 6-methylguanine DNA methyltransferase gene is associated with the loss of nucleosome-like positioning. Mol. Cell Biol., 17, 5813-5822.
    • (1997) Mol. Cell Biol. , vol.17 , pp. 5813-5822
    • Patel, S.A.1    Graunke, D.M.2    Pieper, R.O.3
  • 105
    • 0035313980 scopus 로고    scopus 로고
    • Acquired resistance of melanoma cells to the antineoplastic agent fotemustine is caused by reactivation of the DNA repair gene MGMT
    • Christmann,M., Pick,M., Lage,H., Schadendorf,D. and Kaina,B. (2001) Acquired resistance of melanoma cells to the antineoplastic agent fotemustine is caused by reactivation of the DNA repair gene MGMT. Int. J. Cancer, 92, 123-129.
    • (2001) Int. J. Cancer , vol.92 , pp. 123-129
    • Christmann, M.1    Pick, M.2    Lage, H.3    Schadendorf, D.4    Kaina, B.5
  • 106
  • 107
    • 0033557903 scopus 로고    scopus 로고
    • 6-methylguanine-DNA methyltransferase by promoter hypermethylation is a common event in primary human neoplasia
    • 6-methylguanine-DNA methyltransferase by promoter hypermethylation is a common event in primary human neoplasia. Cancer Res., 59, 793-797.
    • (1999) Cancer Res. , vol.59 , pp. 793-797
    • Esteller, M.1    Hamilton, S.R.2    Burger, P.C.3    Baylin, S.B.4    Herman, J.G.5
  • 108
    • 0037005988 scopus 로고    scopus 로고
    • 6-methylguanine DNA methyltransferase and survival of patients with diffuse large B-cell lymphoma
    • 6-methylguanine DNA methyltransferase and survival of patients with diffuse large B-cell lymphoma. J. Natl Cancer Inst., 94, 26-32.
    • (2002) J. Natl Cancer Inst. , vol.94 , pp. 26-32
    • Esteller, M.1    Gaidano, G.2    Goodman, S.N.3
  • 110
    • 0035575781 scopus 로고    scopus 로고
    • 6-methylguanine-DNA methyltransferase gene is associated significantly with K-ras mutation, lymph node invasion, tumor staging, and disease free survival in patients with gastric carcinoma
    • 6-methylguanine-DNA methyltransferase gene is associated significantly with K-ras mutation, lymph node invasion, tumor staging, and disease free survival in patients with gastric carcinoma. Cancer, 92, 2760-2768.
    • (2001) Cancer , vol.92 , pp. 2760-2768
    • Park, T.J.1    Han, S.U.2    Cho, Y.K.3    Paik, W.K.4    Kim, Y.B.5    Lim, I.K.6
  • 112
    • 0034667523 scopus 로고    scopus 로고
    • 6-alkylguanine-DNA alkyltransferase is phosphorylated by two distinct and novel protein kinases in human brain tumour cells
    • 6-alkylguanine-DNA alkyltransferase is phosphorylated by two distinct and novel protein kinases in human brain tumour cells. Biochem. J., 351(Pt 2), 393-402.
    • (2000) Biochem. J. , vol.351 , Issue.PART 2 , pp. 393-402
    • Mullapudi, S.R.1    Ali-Osman, F.2    Shou, J.3    Srivenugopal, K.S.4
  • 113
    • 0034672345 scopus 로고    scopus 로고
    • Phosphorylation of methylated-DNA-protein-cysteine S-methyltransferase at serine-204 significantly increases its resistance to proteolytic digestion
    • Lim,I.K., Park,T.J. and Paik,W.K. (2000) Phosphorylation of methylated-DNA-protein-cysteine S-methyltransferase at serine-204 significantly increases its resistance to proteolytic digestion. Biochem. J., 352 (Pt 3), 801-808.
    • (2000) Biochem. J. , vol.352 , Issue.PART 3 , pp. 801-808
    • Lim, I.K.1    Park, T.J.2    Paik, W.K.3
  • 114
    • 0036570062 scopus 로고    scopus 로고
    • Clinical relevance of MGMT in the treatment of cancer
    • Gerson,S.L. (2002) Clinical relevance of MGMT in the treatment of cancer. J. Clin. Oncol., 20, 2388-2399.
    • (2002) J. Clin. Oncol. , vol.20 , pp. 2388-2399
    • Gerson, S.L.1
  • 117
  • 118
    • 0034027863 scopus 로고    scopus 로고
    • Gene transfer to suppress bone marrow alkylation sensitivity
    • Roth,R.B. and Samson,L.D. (2000) Gene transfer to suppress bone marrow alkylation sensitivity. Mutat. Res., 462, 107-120.
    • (2000) Mutat. Res. , vol.462 , pp. 107-120
    • Roth, R.B.1    Samson, L.D.2
  • 119
    • 0032861845 scopus 로고    scopus 로고
    • 6-alkylguanine-DNA-alkyltransferase for engineering resistance of haemopoietic progenitor cells to multiple chemotherapeutic agents
    • 6-alkylguanine-DNA-alkyltransferase for engineering resistance of haemopoietic progenitor cells to multiple chemotherapeutic agents. Gene Ther., 6, 1489-1493.
    • (1999) Gene Ther. , vol.6 , pp. 1489-1493
    • Jelinek, J.1    Rafferty, J.A.2    Cmejla, R.3
  • 120
    • 0032031010 scopus 로고    scopus 로고
    • Engineering human DNA alkyltransferases for gene therapy using random sequence mutagenesis
    • Encell,L.P., Coates,M.M. and Loeb,L.A. (1998) Engineering human DNA alkyltransferases for gene therapy using random sequence mutagenesis. Cancer Res., 58, 1013-1020.
    • (1998) Cancer Res. , vol.58 , pp. 1013-1020
    • Encell, L.P.1    Coates, M.M.2    Loeb, L.A.3
  • 121
    • 0036570292 scopus 로고    scopus 로고
    • 6-benzylguanine for patients with nitrosourea-resistant recurrent or progressive malignant glioma
    • 6-benzylguanine for patients with nitrosourea-resistant recurrent or progressive malignant glioma. J. Clin. Oncol., 20, 2277-2283.
    • (2002) J. Clin. Oncol. , vol.20 , pp. 2277-2283
    • Quinn, J.A.1    Pluda, J.2    Dolan, M.E.3
  • 125
    • 0034917119 scopus 로고    scopus 로고
    • Long-time expression of DNA repair enzymes MGMT and APE in human peripheral blood mononuclear cells
    • Janssen,K., Eichhorn-Grombacher,U., Schlink,K., Nitzsche,S., Oesch,F. and Kaina,B. (2001) Long-time expression of DNA repair enzymes MGMT and APE in human peripheral blood mononuclear cells. Arch. Toxicol., 75, 306-312.
    • (2001) Arch. Toxicol. , vol.75 , pp. 306-312
    • Janssen, K.1    Eichhorn-Grombacher, U.2    Schlink, K.3    Nitzsche, S.4    Oesch, F.5    Kaina, B.6
  • 126
    • 45349112521 scopus 로고
    • 6-Methylguanine-DNA methyltransferase in lymphocytes of the elderly with and without Alzheimer's disease
    • 6-Methylguanine-DNA methyltransferase in lymphocytes of the elderly with and without Alzheimer's disease. Mutat. Res., 219, 267-272.
    • (1989) Mutat. Res. , vol.219 , pp. 267-272
    • Edwards, J.A.1    Wang, L.G.2    Setlow, R.B.3    Kaminskas, E.4
  • 128
    • 0021253942 scopus 로고
    • 6-methylguanine-DNA methyltransferase and uracil-DNA glycosylase activities
    • 6-methylguanine-DNA methyltransferase and uracil-DNA glycosylase activities. Mutat. Res., 131, 183-186.
    • (1984) Mutat. Res. , vol.131 , pp. 183-186
    • Myrnes, B.1    Eggset, G.2    Volden, G.3    Krokan, H.4
  • 132
    • 0028990059 scopus 로고
    • 4-ethylthymine in human liver and peripheral blood leukocyte DNA
    • 4-ethylthymine in human liver and peripheral blood leukocyte DNA. Carcinogenesis, 16, 1277-1280.
    • (1995) Carcinogenesis , vol.16 , pp. 1277-1280
    • Kang, H.1    Konishi, C.2    Kuroki, T.3    Huh, N.4
  • 133
    • 0028500761 scopus 로고
    • 6-Methylguanine in blood leucocyte DNA: An association with the geographic prevalence of gastric cancer and with low levels of serum pepsinogen A, a marker of severe chronic atrophic gastritis
    • The EUROGAST Study Group
    • 6-Methylguanine in blood leucocyte DNA: an association with the geographic prevalence of gastric cancer and with low levels of serum pepsinogen A, a marker of severe chronic atrophic gastritis. Carcinogenesis, 15, 1815-1820.
    • (1994) Carcinogenesis , vol.15 , pp. 1815-1820
  • 139
    • 0025743158 scopus 로고
    • The detection of alkylation damage in the DNA of human gastrointestinal tissues
    • Hall,C.N., Badawi,A.F., O'Connor,P.J. and Saffhill,R. (1991) The detection of alkylation damage in the DNA of human gastrointestinal tissues. Br. J. Cancer, 64, 59-63.
    • (1991) Br. J. Cancer , vol.64 , pp. 59-63
    • Hall, C.N.1    Badawi, A.F.2    O'Connor, P.J.3    Saffhill, R.4
  • 141
    • 0024327590 scopus 로고
    • 6-alkylguanine-DNA-alkyltransferase based on the use of an oligonucleotide substrate, and its application to the measurement of DNA repair activity in extracts of biopsy samples of human urinary bladder mucosa
    • 6-alkylguanine-DNA-alkyltransferase based on the use of an oligonucleotide substrate, and its application to the measurement of DNA repair activity in extracts of biopsy samples of human urinary bladder mucosa. Carcinogenesis, 10, 1203-1208.
    • (1989) Carcinogenesis , vol.10 , pp. 1203-1208
    • Souliotis, V.L.1    Giannopoulos, A.2    Koufakis, I.3    Kaila, S.4    Dimopoulos, C.5    Kyrtopoulos, S.A.6


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