Kinetics of O6-methyl-2′-deoxyguanosine repair by O 6-alkylguanine DNA alkyltransferase within K-ras gene-derived DNA sequences

Chemical Research in Toxicology

Volumn 19, Issue 4, 2006, Pages 531-538

  Guza, Rebecca ^a   Rajesh, Mathur ^a   Fang, Qingming ^b   Pegg, Anthony E ^b   Tretyakova, Natalia ^a  

^a UNIVERSITY OF MINNESOTA   (United States)

^b PENN STATE COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 (METHYLNITROSAMINO) 1 (3 PYRIDYL) 1 BUTANONE; 6 O ALKYLGUANINE DNA ALKYLTRANSFERASE; 6 O METHYL 2' DEOXYGUANOSINE; ADENINE; ALKYL GROUP; ALKYLATING AGENT; CYSTEINE; DOUBLE STRANDED DNA; GUANINE; GUANOSINE DERIVATIVE; NITROSAMINE; PURINE DERIVATIVE; RECOMBINANT PROTEIN; THIOL; TOBACCO SMOKE; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL REACTION KINETICS; CODON; DEMETHYLATION; DNA ADDUCT; DNA CONFORMATION; DNA FLANKING REGION; DNA MODIFICATION; DNA REPAIR; DNA SEQUENCE; ELECTROSPRAY MASS SPECTROMETRY; ENERGY TRANSFER; ENZYME ACTIVE SITE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYDROLYSIS; ISOTOPE DILUTION ASSAY; LUNG TUMOR; METHYLATION; MUTAGENICITY; NUCLEIC ACID BASE SUBSTITUTION; ONCOGENE K RAS; SMOKING;

BASE SEQUENCE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DEOXYGUANOSINE; DNA; DNA PRIMERS; DNA REPAIR; GENES, RAS; HUMANS; KINETICS; O(6)-METHYLGUANINE-DNA METHYLTRANSFERASE; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;

ANIMALIA; NICOTIANA TABACUM;

EID: 33646083945     PISSN: 0893228X     EISSN: None     Source Type: Journal    
DOI: 10.1021/tx050348d     Document Type: Article

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