The Repair of the Tobacco Specific Nitrosamine Derived Adduct O 6-[4-Oxo-4-(3-pyridyl)butyl]guanine by O 6-Alkylguanine-DNA Alkyltransferase Variants

Chemical Research in Toxicology

Volumn 17, Issue 3, 2004, Pages 424-434

  Mijal, Renée S ^a   Thomson, Nicole M ^a   Fleischer, Nancy L ^a   Pauly, Gary T ^b   Moschel, Robert C ^b   Kanugula, Sreenivas ^c   Fang, Qingming ^c   Pegg, Anthony E ^c   Peterson, Lisa A ^a  

^a UNIVERSITY OF MINNESOTA   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

^c PENN STATE MILTON S HERSHEY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 (METHYLNITROSAMINO) 1 (3 PYRIDYL) 1 BUTANONE; 6 O [4 OXO 4 (3 PYRIDYL)BUTYL]GUANINE; 6 O ALKYLGUANINE DNA ALKYLTRANSFERASE; 6 O BENZYLGUANINE; 6 O BUTYLGUANINE; 6 O METHYLGUANINE; CARCINOGEN; CYSTEINE; GUANINE DERIVATIVE; MUTANT PROTEIN; NITROSAMINE; OLIGODEOXYNUCLEOTIDE; PROMUTAGEN; PYRIDINE DERIVATIVE; PYRIDYLOXOBUTYL DERIVATIVE; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; AMINO ACID TRANSPORT; ARTICLE; BINDING AFFINITY; BINDING SITE; CARCINOGENICITY; CHEMICAL REACTION; CHEMICAL STRUCTURE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; DNA ADDUCT; DNA REPAIR; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME STRUCTURE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; METHYLATION; MOLECULAR INTERACTION; MOLECULAR SIZE; MOUSE; MUTAGENICITY; NONHUMAN; NUCLEOTIDE SEQUENCE; POLYACRYLAMIDE GEL ELECTROPHORESIS; RAT; REACTION ANALYSIS; SEQUENCE ALIGNMENT; STRUCTURE ANALYSIS; SYNTHESIS; TOBACCO; WILD TYPE;

ANIMALS; CARCINOGENS; CATTLE; DNA ADDUCTS; DNA REPAIR; GUANINE; HUMANS; KINETICS; MICE; NITROSAMINES; O(6)-METHYLGUANINE-DNA METHYLTRANSFERASE; RATS; SPECIES SPECIFICITY;

BACTERIA (MICROORGANISMS); MAMMALIA; NICOTIANA TABACUM;

EID: 1642359266     PISSN: 0893228X     EISSN: None     Source Type: Journal    
DOI: 10.1021/tx0342417     Document Type: Article

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