Quantitative trait locus analysis reveals two intragenic sites that influence O6-alkylguanine-DNA alkyltransferase activity in peripheral blood mononuclear cells

Carcinogenesis

Volumn 26, Issue 8, 2005, Pages 1473-1480

  Margison, Geoffrey P ^a   Heighway, Jim ^b   Pearson, Steven ^a   McGown, Gail ^a   Thorncroft, Mary R ^a   Watson, Amanda J ^a   Harrison, Kathryn L ^c   Lewis, Sarah J ^c   Rohde, Klaus ^d   Barber, Philip V ^e   O'Donnell, Paul ^e   Povey, Andrew C ^c   Santibáñez Koref, Mauro F ^f  

^a CHRISTIE HOSPITAL   (United Kingdom)

^b UNIVERSITY OF LIVERPOOL   (United Kingdom)

^c UNIVERSITY OF MANCHESTER   (United Kingdom)

^d MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

^e WYTHENSHAWE HOSPITAL   (United Kingdom)

^f NEWCASTLE UNIVERSITY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

6 O ALKYLGUANINE DNA ALKYLTRANSFERASE; CYSTEINE; ISOLEUCINE; VALINE; METHYLATED DNA PROTEIN CYSTEINE METHYLTRANSFERASE; PRIMER DNA;

3' UNTRANSLATED REGION; ADULT; ALLELE; AMINO ACID SUBSTITUTION; ARTICLE; CONTROLLED STUDY; DNA METHYLATION; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME INACTIVATION; EXON; FEMALE; GENE EXPRESSION; GENE LINKAGE DISEQUILIBRIUM; GENETIC VARIABILITY; HUMAN; HUMAN CELL; IN VITRO STUDY; INHERITANCE; INTRON; LUNG CANCER; MAJOR CLINICAL STUDY; MALE; NUCLEOTIDE SEQUENCE; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; QUANTITATIVE TRAIT LOCUS; SINGLE NUCLEOTIDE POLYMORPHISM; CODON; ENZYMOLOGY; GENE EXPRESSION REGULATION; GENETIC PREDISPOSITION; GENETICS; GENOTYPE; LUNG TUMOR; MONONUCLEAR CELL;

BASE SEQUENCE; CODON; DNA PRIMERS; EXONS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; LEUKOCYTES, MONONUCLEAR; LUNG NEOPLASMS; O(6)-METHYLGUANINE-DNA METHYLTRANSFERASE; POLYMORPHISM, SINGLE NUCLEOTIDE; QUANTITATIVE TRAIT LOCI;

EID: 24944443492     PISSN: 01433334     EISSN: 14602180     Source Type: Journal    
DOI: 10.1093/carcin/bgi087     Document Type: Article

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