The structural basis for the mutagenicity of O6-methyl-guanine lesions

Proceedings of the National Academy of Sciences of the United States of America

Volumn 103, Issue 52, 2006, Pages 19701-19706

  Warren, Joshua J ^a   Forsberg, Lawrence J ^a   Beese, Lorena S ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Crystal structure; DNA damage; DNA polymerase; Protein DNA complex

Indexed keywords

6 O METHYLGUANINE; ANTINEOPLASTIC AGENT; CYTOSINE; DNA POLYMERASE; NUCLEOTIDE; THYMINE;

ARTICLE; CANCER THERAPY; CARCINOGENESIS; CARCINOGENICITY; CONTROLLED STUDY; DNA DAMAGE; DNA METHYLATION; DNA PROTEIN COMPLEX; DNA TEMPLATE; ELECTRICITY; ENZYME SPECIFICITY; GEOBACILLUS STEAROTHERMOPHILUS; HYDROGEN BOND; MOLECULAR MIMICRY; MUTAGENICITY; NONHUMAN; PRIORITY JOURNAL; STEREOCHEMISTRY;

BINDING SITES; CRYSTALLOGRAPHY, X-RAY; DNA; DNA-DIRECTED DNA POLYMERASE; GUANINE; KINETICS; MODELS, MOLECULAR; MUTATION; PROTEIN STRUCTURE, TERTIARY;

GEOBACILLUS STEAROTHERMOPHILUS;

EID: 33845935791     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0609580103     Document Type: Article

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