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Volumn 11, Issue 7, 2010, Pages 537-561

MicroRNA: Biogenesis, function and role in cancer

Author keywords

Cancer; MicroRNA; Post transcriptional gene regulation; RNA interference (RNAi)

Indexed keywords

DNA DIRECTED RNA POLYMERASE III; MESSENGER RNA; MICRORNA; RNA INDUCED SILENCING COMPLEX; RNA POLYMERASE II; UNTRANSLATED RNA;

EID: 78650004201     PISSN: 13892029     EISSN: None     Source Type: Journal    
DOI: 10.2174/138920210793175895     Document Type: Article
Times cited : (1409)

References (381)
  • 1
    • 38449100766 scopus 로고    scopus 로고
    • Protein interactions and complexes in human microRNA biogenesis and function
    • Perron, M. P.; Provost, P. Protein interactions and complexes in human microRNA biogenesis and function. Front. Biosci., 2008, 13, 2537-2547.
    • (2008) Front. Biosci , vol.13 , pp. 2537-2547
    • Perron, M.P.1    Provost, P.2
  • 2
    • 0027730383 scopus 로고
    • Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediated temporal pattern formation in C. elegans
    • Wightman, B. H. I.; Ruvkun, G. Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediated temporal pattern formation in C. elegans. Cell, 1993, 75, 855-862.
    • (1993) Cell , vol.75 , pp. 855-862
    • Wightman, B.H.I.1    Ruvkun, G.2
  • 3
    • 0027751663 scopus 로고
    • The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14
    • Lee, R.C. F. R.; Ambros, V. The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14. Cell, 1993, 75, 843-854.
    • (1993) Cell , vol.75 , pp. 843-854
    • Lee, R.C.F.R.1    Ambros, V.2
  • 4
    • 33748354897 scopus 로고    scopus 로고
    • L(ou)sy miRNA targets?
    • Rajewsky, N. L(ou)sy miRNA targets? Nat. Struct. Mol. Biol. 2006, 13, 754-755.
    • (2006) Nat. Struct. Mol. Biol , vol.13 , pp. 754-755
    • Rajewsky, N.1
  • 5
    • 33745248430 scopus 로고    scopus 로고
    • MicroRNA target predictions in animals
    • Rajewsky, N. microRNA target predictions in animals. Nat. Genet., 2006, 38(Suppl), S8-13.
    • (2006) Nat. Genet , vol.38 , Issue.SUPPL
    • Rajewsky, N.1
  • 7
    • 11844262661 scopus 로고    scopus 로고
    • Phylogenetic shadowing and computational identification of human microRNA genes
    • Berezikov, E.; Guryev, V.; van de Belt, J.; Wienholds, E.; Plasterk, R. H.; Cuppen, E. Phylogenetic shadowing and computational identification of human microRNA genes. Cell, 2005, 120, 21-24.
    • (2005) Cell , vol.120 , pp. 21-24
    • Berezikov, E.1    Guryev, V.2    van de, B.J.3    Wienholds, E.4    Plasterk, R.H.5    Cuppen, E.6
  • 9
    • 33749059160 scopus 로고    scopus 로고
    • miRBase: The microRNA sequence database
    • Griffiths-Jones, S. miRBase: the microRNA sequence database. Methods Mol. Biol., 2006, 342, 129-138.
    • (2006) Methods Mol. Biol , vol.342 , pp. 129-138
    • Griffiths-Jones, S.1
  • 12
    • 10944254152 scopus 로고    scopus 로고
    • Transcription and processing of human microRNA precursors
    • Cullen, B. R. Transcription and processing of human microRNA precursors. Mol. Cell, 2004, 16, 861-865.
    • (2004) Mol. Cell , vol.16 , pp. 861-865
    • Cullen, B.R.1
  • 15
    • 22444437609 scopus 로고    scopus 로고
    • Serum response factor regulates a muscle-specific microRNA that targets Hand2 during cardiogenesis
    • Zhao, Y.; Samal, E.; Srivastava, D. Serum response factor regulates a muscle-specific microRNA that targets Hand2 during cardiogenesis. Nature, 2005, 436, 214-220.
    • (2005) Nature , vol.436 , pp. 214-220
    • Zhao, Y.1    Samal, E.2    Srivastava, D.3
  • 19
    • 4644309196 scopus 로고    scopus 로고
    • The functions of animal microRNAs
    • Ambros, V. The functions of animal microRNAs. Nature, 2004, 431, 350-355.
    • (2004) Nature , vol.431 , pp. 350-355
    • Ambros, V.1
  • 20
    • 0347444723 scopus 로고    scopus 로고
    • MicroRNAs: Genomics, biogenesis, mechanism, and function
    • Bartel, D. P. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell, 2004, 116, 281-297.
    • (2004) Cell , vol.116 , pp. 281-297
    • Bartel, D.P.1
  • 21
    • 33947431322 scopus 로고    scopus 로고
    • Disrupting the pairing between let-7 and Hmga2 enhances oncogenic transformation
    • Mayr, C.; Hemann, M. T.; Bartel, D. P. Disrupting the pairing between let-7 and Hmga2 enhances oncogenic transformation. Science, 2007, 315(5818), 1576-9.
    • (2007) Science , vol.315 , Issue.5818 , pp. 1576-1579
    • Mayr, C.1    Hemann, M.T.2    Bartel, D.P.3
  • 22
    • 34247565615 scopus 로고    scopus 로고
    • The tumor suppressor microRNA let-7 represses the HMGA2 oncogene
    • Lee, Y. S.; Dutta, A. The tumor suppressor microRNA let-7 represses the HMGA2 oncogene. Genes Dev., 2007, 21, 1025-1030.
    • (2007) Genes Dev , vol.21 , pp. 1025-1030
    • Lee, Y.S.1    Dutta, A.2
  • 25
    • 38349186896 scopus 로고    scopus 로고
    • MicroRNAs (miRNAs) in neurodegenerative diseases
    • Nelson, P. T.; Wang, W. X.; Rajeev, B. W. MicroRNAs (miRNAs) in neurodegenerative diseases. Brain Pathol., 2008, 18, 130-138.
    • (2008) Brain Pathol , vol.18 , pp. 130-138
    • Nelson, P.T.1    Wang, W.X.2    Rajeev, B.W.3
  • 26
    • 38749095507 scopus 로고    scopus 로고
    • The expression of microRNA miR-107 decreases early in Alzheimer's disease and may accelerate disease progression through regulation of beta-site amyloid precursor protein-cleaving enzyme 1
    • Wang, W. X.; Rajeev, B. W.; Stromberg, A. J.; Ren, N.; Tang, G.; Huang, Q.; Rigoutsos, I.; Nelson, P. T. The expression of microRNA miR-107 decreases early in Alzheimer's disease and may accelerate disease progression through regulation of beta-site amyloid precursor protein-cleaving enzyme 1. J. Neurosci., 2008, 28, 1213-1223.
    • (2008) J. Neurosci , vol.28 , pp. 1213-1223
    • Wang, W.X.1    Rajeev, B.W.2    Stromberg, A.J.3    Ren, N.4    Tang, G.5    Huang, Q.6    Rigoutsos, I.7    Nelson, P.T.8
  • 28
    • 34249086851 scopus 로고    scopus 로고
    • MiRNA profiling for diagnosis and prognosis of human cancer
    • Jay, C.; Nemunaitis, J.; Chen, P.; Fulgham, P.; Tong, A. W. MiRNA profiling for diagnosis and prognosis of human cancer. DNA Cell Biol., 2007, 26, 293-300.
    • (2007) DNA Cell Biol , vol.26 , pp. 293-300
    • Jay, C.1    Nemunaitis, J.2    Chen, P.3    Fulgham, P.4    Tong, A.W.5
  • 29
    • 34250353602 scopus 로고    scopus 로고
    • MicroRNAs and cancer: Role in tumorigenesis, patient classification and therapy
    • Hernando, E. MicroRNAs and cancer: role in tumorigenesis, patient classification and therapy. Clin. Transl. Oncol., 2007, 9, 155-160.
    • (2007) Clin. Transl. Oncol , vol.9 , pp. 155-160
    • Hernando, E.1
  • 30
    • 38749083425 scopus 로고    scopus 로고
    • MicroRNAs and cancer: Profile, profile, profile
    • Barbarotto, E.; Schmittgen, T. D.; Calin, G. A. MicroRNAs and cancer: profile, profile, profile. Int. J. Cancer, 2008, 122, 969-977.
    • (2008) Int. J. Cancer , vol.122 , pp. 969-977
    • Barbarotto, E.1    Schmittgen, T.D.2    Calin, G.A.3
  • 33
    • 18344369543 scopus 로고    scopus 로고
    • MicroRNA biogenesis: Coordinated cropping and dicing
    • Kim, V. N. MicroRNA biogenesis: coordinated cropping and dicing. Nat. Rev. Mol. Cell. Biol., 2005, 6, 376-385.
    • (2005) Nat. Rev. Mol. Cell. Biol , vol.6 , pp. 376-385
    • Kim, V.N.1
  • 34
    • 18344373363 scopus 로고    scopus 로고
    • Small RNAs: Classification, biogenesis, and function
    • Kim, V. N. Small RNAs: classification, biogenesis, and function. Mol. Cells, 2005, 19, 1-15.
    • (2005) Mol. Cells , vol.19 , pp. 1-15
    • Kim, V.N.1
  • 36
    • 6344281172 scopus 로고    scopus 로고
    • Identification of mammalian microRNA host genes and transcription units
    • Rodriguez, A.; Griffiths-Jones, S.; Ashurst, J. L.; Bradley, A. Identification of mammalian microRNA host genes and transcription units. Genome Res., 2004, 14, 1902-1910.
    • (2004) Genome Res , vol.14 , pp. 1902-1910
    • Rodriguez, A.1    Griffiths-Jones, S.2    Ashurst, J.L.3    Bradley, A.4
  • 37
    • 77954052354 scopus 로고    scopus 로고
    • Intron-mediated RNA interference, intronic microRNAs, and applications
    • Ying, S. Y.; Chang, C. P.; Lin, S. L. Intron-mediated RNA interference, intronic microRNAs, and applications. Methods Mol. Biol., 2010, 629, 205-237.
    • (2010) Methods Mol. Biol , vol.629 , pp. 205-237
    • Ying, S.Y.1    Chang, C.P.2    Lin, S.L.3
  • 40
    • 33748286897 scopus 로고    scopus 로고
    • Human microRNA clusters: Genomic organization and expression profile in leukemia cell lines
    • Yu, J.; Wang, F.; Yang, G. H.; Wang, F. L.; Ma, Y. N.; Du, Z. W.; Zhang, J. W. Human microRNA clusters: genomic organization and expression profile in leukemia cell lines. Biochem. Biophys. Res. Commun., 2006, 349, 59-68.
    • (2006) Biochem. Biophys. Res. Commun , vol.349 , pp. 59-68
    • Yu, J.1    Wang, F.2    Yang, G.H.3    Wang, F.L.4    Ma, Y.N.5    Du, Z.W.6    Zhang, J.W.7
  • 41
    • 1842427197 scopus 로고    scopus 로고
    • Derivation and function of small interfering RNAs and microRNAs
    • Cullen, B. R. Derivation and function of small interfering RNAs and microRNAs. Virus Res., 2004, 102, 3-9.
    • (2004) Virus Res , vol.102 , pp. 3-9
    • Cullen, B.R.1
  • 42
    • 8144225486 scopus 로고    scopus 로고
    • MicroRNA genes are transcribed by RNA polymerase II
    • Lee, Y.; Kim, M.; Han, J.; Yeom, K. H.; Lee, S.; Baek, S. H.; Kim, V. N. MicroRNA genes are transcribed by RNA polymerase II. EMBO J., 2004, 23, 4051-4060.
    • (2004) EMBO J , vol.23 , pp. 4051-4060
    • Lee, Y.1    Kim, M.2    Han, J.3    Yeom, K.H.4    Lee, S.5    Baek, S.H.6    Kim, V.N.7
  • 43
    • 9344235449 scopus 로고    scopus 로고
    • Human microRNAs are processed from capped, polyadenylated transcripts that can also function as mRNAs
    • Cai, X.; Hagedorn, C. H.; Cullen, B. R. Human microRNAs are processed from capped, polyadenylated transcripts that can also function as mRNAs. RNA, 2004, 10, 1957-1966.
    • (2004) RNA , vol.10 , pp. 1957-1966
    • Cai, X.1    Hagedorn, C.H.2    Cullen, B.R.3
  • 44
    • 1942435249 scopus 로고    scopus 로고
    • Micromanagers of gene expression: The potentially widespread influence of metazoan microRNAs
    • Bartel, D. P.; Chen, C. Z. Micromanagers of gene expression: the potentially widespread influence of metazoan microRNAs. Nat. Rev. Genet., 2004, 5, 396-400.
    • (2004) Nat. Rev. Genet , vol.5 , pp. 396-400
    • Bartel, D.P.1    Chen, C.Z.2
  • 45
    • 1242273889 scopus 로고    scopus 로고
    • Structure and function of RNA polymerase II
    • Cramer, P. Structure and function of RNA polymerase II. Adv. Protein Chem., 2004, 67, 1-42.
    • (2004) Adv. Protein Chem , vol.67 , pp. 1-42
    • Cramer, P.1
  • 46
    • 0033087907 scopus 로고    scopus 로고
    • Function and structural biology of general transcription factors and RNA polymerase II in eukaryotes
    • Ohkuma, Y. [Function and structural biology of general transcription factors and RNA polymerase II in eukaryotes]. Tanpakushitsu Kakusan Koso, 1999, 44, 438-456.
    • (1999) Tanpakushitsu Kakusan Koso , vol.44 , pp. 438-456
    • Ohkuma, Y.1
  • 47
    • 0024986518 scopus 로고
    • RNA polymerase II: Subunit structure and function
    • Woychik, N. A.; Young, R. A. RNA polymerase II: subunit structure and function. Trends Biochem. Sci., 1990, 15, 347-351.
    • (1990) Trends Biochem. Sci , vol.15 , pp. 347-351
    • Woychik, N.A.1    Young, R.A.2
  • 48
    • 35848963394 scopus 로고    scopus 로고
    • Regulation of RNA polymerase III transcription during mammalian cell growth
    • Goodfellow, S. J.; White, R. J. Regulation of RNA polymerase III transcription during mammalian cell growth. Cell Cycle, 2007, 6, 2323-2326.
    • (2007) Cell Cycle , vol.6 , pp. 2323-2326
    • Goodfellow, S.J.1    White, R.J.2
  • 51
    • 0028828102 scopus 로고
    • Cell cycle regulation of RNA polymerase III transcription
    • White, R. J.; Gottlieb, T. M.; Downes, C. S.; Jackson, S. P. Cell cycle regulation of RNA polymerase III transcription. Mol. Cell Biol., 1995, 15, 6653-6662.
    • (1995) Mol. Cell Biol , vol.15 , pp. 6653-6662
    • White, R.J.1    Gottlieb, T.M.2    Downes, C.S.3    Jackson, S.P.4
  • 52
    • 0035044015 scopus 로고    scopus 로고
    • RNA polymerase III transcription complexes on chromosomal 5S rRNA genes in vivo: TFIIIB occupancy and promoter opening
    • Costanzo, G.; Camier, S.; Carlucci, P.; Burderi, L.; Negri, R. RNA polymerase III transcription complexes on chromosomal 5S rRNA genes in vivo: TFIIIB occupancy and promoter opening. Mol. Cell Biol., 2001, 21, 3166-3178.
    • (2001) Mol. Cell Biol , vol.21 , pp. 3166-3178
    • Costanzo, G.1    Camier, S.2    Carlucci, P.3    Burderi, L.4    Negri, R.5
  • 53
    • 0026078524 scopus 로고
    • Sequences far downstream from the classical tRNA promoter elements bind RNA polymerase III transcription factors
    • Young, L. S.; Rivier, D. H.; Sprague, K. U. Sequences far downstream from the classical tRNA promoter elements bind RNA polymerase III transcription factors. Mol. Cell Biol., 1991, 11, 1382-1392.
    • (1991) Mol. Cell Biol , vol.11 , pp. 1382-1392
    • Young, L.S.1    Rivier, D.H.2    Sprague, K.U.3
  • 54
    • 0025063806 scopus 로고
    • DNA methylation inhibits transcription by RNA polymerase III of a tRNA gene, but not of a 5S rRNA gene
    • Besser, D.; Gotz, F.; Schulze-Forster, K.; Wagner, H.; Kroger, H.; Simon, D. DNA methylation inhibits transcription by RNA polymerase III of a tRNA gene, but not of a 5S rRNA gene. FEBS Lett., 1990, 269, 358-362.
    • (1990) FEBS Lett , vol.269 , pp. 358-362
    • Besser, D.1    Gotz, F.2    Schulze-Forster, K.3    Wagner, H.4    Kroger, H.5    Simon, D.6
  • 55
    • 0024360443 scopus 로고
    • Transcription factor IIIB generates extended DNA interactions in RNA polymerase III transcription complexes on tRNA genes
    • Kassavetis, G. A.; Riggs, D. L.; Negri, R.; Nguyen, L. H.; Geiduschek, E. P. Transcription factor IIIB generates extended DNA interactions in RNA polymerase III transcription complexes on tRNA genes. Mol. Cell Biol., 1989, 9, 2551-2566.
    • (1989) Mol. Cell Biol , vol.9 , pp. 2551-2566
    • Kassavetis, G.A.1    Riggs, D.L.2    Negri, R.3    Nguyen, L.H.4    Geiduschek, E.P.5
  • 56
    • 0346727524 scopus 로고    scopus 로고
    • MicroRNAs modulate hematopoietic lineage differentiation
    • Chen, C. Z.; Li, L.; Lodish, H. F.; Bartel, D. P. MicroRNAs modulate hematopoietic lineage differentiation. Science, 2004, 303, 83-86.
    • (2004) Science , vol.303 , pp. 83-86
    • Chen, C.Z.1    Li, L.2    Lodish, H.F.3    Bartel, D.P.4
  • 58
    • 84886639593 scopus 로고
    • End-to-end transcription of an Alu family repeat. A new type of polymerase-III-dependent terminator and its evolutionary implication
    • Hess, J.; Perez-Stable, C.; Wu, G. J.; Weir, B.; Tinoco, I., Jr. Shen, C. K. End-to-end transcription of an Alu family repeat. A new type of polymerase-III-dependent terminator and its evolutionary implication. J. Mol. Biol., 1985, 184, 7-21.
    • (1985) J. Mol. Biol , vol.184 , pp. 7-21
    • Hess, J.1    Perez-Stable, C.2    Wu, G.J.3    Weir, B.4    Tinoco Jr., I.5    Shen, C.K.6
  • 59
    • 73149098353 scopus 로고    scopus 로고
    • Alu-directed transcriptional regulation of some novel miRNAs
    • Gu, T. J.; Yi, X.; Zhao, X. W.; Zhao, Y.; Yin, J. Q. Alu-directed transcriptional regulation of some novel miRNAs. BMC Genomics, 2009, 10, 563.
    • (2009) BMC Genomics , vol.10 , pp. 563
    • Gu, T.J.1    Yi, X.2    Zhao, X.W.3    Zhao, Y.4    Yin, J.Q.5
  • 60
    • 3142726606 scopus 로고    scopus 로고
    • Identification of microRNAs and other tiny noncoding RNAs by cDNA cloning
    • Ambros, V.; Lee, R. C. Identification of microRNAs and other tiny noncoding RNAs by cDNA cloning. Methods Mol. Biol., 2004, 265, 131-158.
    • (2004) Methods Mol. Biol , vol.265 , pp. 131-158
    • Ambros, V.1    Lee, R.C.2
  • 61
    • 33846277696 scopus 로고    scopus 로고
    • Repression of protein synthesis by miRNAs: How many mechanisms?
    • Pillai, R. S.; Bhattacharyya, S. N.; Filipowicz, W. Repression of protein synthesis by miRNAs: how many mechanisms? Trends Cell Biol., 2007, 17, 118-126.
    • (2007) Trends Cell Biol , vol.17 , pp. 118-126
    • Pillai, R.S.1    Bhattacharyya, S.N.2    Filipowicz, W.3
  • 62
    • 33748587841 scopus 로고    scopus 로고
    • A pattern-based method for the identification of MicroRNA binding sites and their corresponding heteroduplexes
    • Miranda, K. C.; Huynh, T.; Tay, Y.; Ang, Y. S.; Tam, W. L.; Thomson, A. M.; Lim, B.; Rigoutsos, I. A pattern-based method for the identification of MicroRNA binding sites and their corresponding heteroduplexes. Cell, 2006, 126, 1203-1217.
    • (2006) Cell , vol.126 , pp. 1203-1217
    • Miranda, K.C.1    Huynh, T.2    Tay, Y.3    Ang, Y.S.4    Tam, W.L.5    Thomson, A.M.6    Lim, B.7    Rigoutsos, I.8
  • 63
    • 48349133693 scopus 로고    scopus 로고
    • Evidence for dietary regulation of microRNA expression in cancer cells
    • Davis, C. D.; Ross, S. A. Evidence for dietary regulation of microRNA expression in cancer cells. Nutr. Rev., 2008, 66, 477-482.
    • (2008) Nutr. Rev , vol.66 , pp. 477-482
    • Davis, C.D.1    Ross, S.A.2
  • 64
    • 56749087994 scopus 로고    scopus 로고
    • Hormonal regulation of microRNA expression in periovulatory mouse mural granulosa cells
    • Fiedler, S. D.; Carletti, M. Z.; Hong, X.; Christenson, L. K. Hormonal regulation of microRNA expression in periovulatory mouse mural granulosa cells. Biol. Reprod., 2008, 79(6), 1030-7.
    • (2008) Biol. Reprod , vol.79 , Issue.6 , pp. 1030-1037
    • Fiedler, S.D.1    Carletti, M.Z.2    Hong, X.3    Christenson, L.K.4
  • 69
    • 34047264639 scopus 로고    scopus 로고
    • Direct regulation of an oncogenic micro-RNA cluster by E2F transcription factors
    • Woods, K.; Thomson, J. M.; Hammond, S. M. Direct regulation of an oncogenic micro-RNA cluster by E2F transcription factors. J. Biol. Chem., 2007, 282, 2130-2134.
    • (2007) J. Biol. Chem , vol.282 , pp. 2130-2134
    • Woods, K.1    Thomson, J.M.2    Hammond, S.M.3
  • 70
    • 77955484492 scopus 로고    scopus 로고
    • Smad proteins bind a conserved RNA sequence to promote microRNA maturation by Drosha
    • Davis, B. N.; Hilyard, A. C.; Nguyen, P. H.; Lagna, G.; Hata, A. Smad proteins bind a conserved RNA sequence to promote microRNA maturation by Drosha. Mol. Cell, 2010, 39, 373-384.
    • (2010) Mol. Cell , vol.39 , pp. 373-384
    • Davis, B.N.1    Hilyard, A.C.2    Nguyen, P.H.3    Lagna, G.4    Hata, A.5
  • 71
    • 55049119136 scopus 로고    scopus 로고
    • Posttranscriptional regulation of miRNAs harboring conserved terminal loops
    • Michlewski, G.; Guil, S.; Semple, C. A.; Caceres, J. F. Posttranscriptional regulation of miRNAs harboring conserved terminal loops. Mol. Cell., 2008, 32, 383-393.
    • (2008) Mol. Cell , vol.32 , pp. 383-393
    • Michlewski, G.1    Guil, S.2    Semple, C.A.3    Caceres, J.F.4
  • 72
    • 77049099101 scopus 로고    scopus 로고
    • Lin28: A microRNA regulator with a macro role
    • Viswanathan, S. R.; Daley, G. Q. Lin28: A microRNA regulator with a macro role. Cell, 2010, 140, 445-449.
    • (2010) Cell , vol.140 , pp. 445-449
    • Viswanathan, S.R.1    Daley, G.Q.2
  • 75
    • 9144224451 scopus 로고    scopus 로고
    • Processing of primary microRNAs by the Microprocessor complex
    • Denli, A. M.; Tops, B. B.; Plasterk, R. H.; Ketting, R. F.; Hannon, G. J. Processing of primary microRNAs by the Microprocessor complex. Nature, 2004, 432, 231-235.
    • (2004) Nature , vol.432 , pp. 231-235
    • Denli, A.M.1    Tops, B.B.2    Plasterk, R.H.3    Ketting, R.F.4    Hannon, G.J.5
  • 76
    • 28044455435 scopus 로고    scopus 로고
    • microPrimer: The biogenesis and function of microRNA
    • Du, T.; Zamore, P. D. microPrimer: the biogenesis and function of microRNA. Development, 2005, 132, 4645-4652.
    • (2005) Development , vol.132 , pp. 4645-4652
    • Du, T.1    Zamore, P.D.2
  • 78
    • 10644234841 scopus 로고    scopus 로고
    • The Drosha-DGCR8 complex in primary microRNA processing
    • Han, J.; Lee, Y.; Yeom, K. H.; Kim, Y. K.; Jin, H.; Kim, V. N. The Drosha-DGCR8 complex in primary microRNA processing. Genes Dev., 2004, 18, 3016-3027.
    • (2004) Genes Dev , vol.18 , pp. 3016-3027
    • Han, J.1    Lee, Y.2    Yeom, K.H.3    Kim, Y.K.4    Jin, H.5    Kim, V.N.6
  • 79
    • 0035800521 scopus 로고    scopus 로고
    • A cellular function for the RNAinterference enzyme Dicer in the maturation of the let-7 small temporal RNA
    • Hutvagner, G.; McLachlan, J.; Pasquinelli, A. E.; Balint, E.; Tuschl, T.; Zamore, P. D. A cellular function for the RNAinterference enzyme Dicer in the maturation of the let-7 small temporal RNA. Science, 2001, 293, 834-838.
    • (2001) Science , vol.293 , pp. 834-838
    • Hutvagner, G.1    McLachlan, J.2    Pasquinelli, A.E.3    Balint, E.4    Tuschl, T.5    Zamore, P.D.6
  • 81
    • 0037009364 scopus 로고    scopus 로고
    • MicroRNA maturation: Stepwise processing and subcellular localization
    • Lee, Y.; Jeon, K.; Lee, J. T.; Kim, S.; Kim, V. N. MicroRNA maturation: stepwise processing and subcellular localization. EMBO J., 2002, 21, 4663-4670.
    • (2002) EMBO J , vol.21 , pp. 4663-4670
    • Lee, Y.1    Jeon, K.2    Lee, J.T.3    Kim, S.4    Kim, V.N.5
  • 82
    • 38449116843 scopus 로고    scopus 로고
    • Intron-mediated RNA interference and microRNA (miRNA)
    • Lin, S. L.; Kim, H.; Ying, S. Y. Intron-mediated RNA interference and microRNA (miRNA). Front. Biosci., 2008, 13, 2216-2230.
    • (2008) Front. Biosci , vol.13 , pp. 2216-2230
    • Lin, S.L.1    Kim, H.2    Ying, S.Y.3
  • 83
  • 84
    • 24144494563 scopus 로고    scopus 로고
    • The let-7 MicroRNA family members mir-48, mir-84, and mir-241 function together to regulate developmental timing in Caenorhabditis elegans
    • Abbott, A. L.; Alvarez-Saavedra, E.; Miska, E. A.; Lau, N. C.; Bartel, D. P.; Horvitz, H. R.; Ambros, V. The let-7 MicroRNA family members mir-48, mir-84, and mir-241 function together to regulate developmental timing in Caenorhabditis elegans. Dev. Cell, 2005, 9, 403-414.
    • (2005) Dev. Cell , vol.9 , pp. 403-414
    • Abbott, A.L.1    Alvarez-Saavedra, E.2    Miska, E.A.3    Lau, N.C.4    Bartel, D.P.5    Horvitz, H.R.6    Ambros, V.7
  • 85
    • 11844297347 scopus 로고    scopus 로고
    • Use of RNA polymerase II to transcribe artificial microRNAs
    • Zeng, Y.; Cai, X.; Cullen, B. R. Use of RNA polymerase II to transcribe artificial microRNAs. Methods Enzymol., 2005, 392, 371-380.
    • (2005) Methods Enzymol , vol.392 , pp. 371-380
    • Zeng, Y.1    Cai, X.2    Cullen, B.R.3
  • 86
    • 0037273432 scopus 로고    scopus 로고
    • Sequence requirements for micro RNA processing and function in human cells
    • Zeng, Y.; Cullen, B. R. Sequence requirements for micro RNA processing and function in human cells. RNA, 2003, 9, 112-123.
    • (2003) RNA , vol.9 , pp. 112-123
    • Zeng, Y.1    Cullen, B.R.2
  • 87
    • 23044502585 scopus 로고    scopus 로고
    • Efficient processing of primary microRNA hairpins by Drosha requires flanking nonstructured RNA sequences
    • Zeng, Y.; Cullen, B. R. Efficient processing of primary microRNA hairpins by Drosha requires flanking nonstructured RNA sequences. J. Biol. Chem., 2005, 280, 27595-27603.
    • (2005) J. Biol. Chem , vol.280 , pp. 27595-27603
    • Zeng, Y.1    Cullen, B.R.2
  • 88
    • 78649870594 scopus 로고    scopus 로고
    • The terminal loop region controls microRNA processing by Drosha and Dicer
    • Epub ahead of print
    • Zhang, X.; Zeng, Y. The terminal loop region controls microRNA processing by Drosha and Dicer. Nucleic Acids Res., 2010, [Epub ahead of print].
    • (2010) Nucleic Acids Res
    • Zhang, X.1    Zeng, Y.2
  • 90
    • 66449118741 scopus 로고    scopus 로고
    • Posttranscriptional control of DGCR8 expression by the Microprocessor
    • Triboulet, R.; Chang, H. M.; Lapierre, R. J.; Gregory, R. I. Posttranscriptional control of DGCR8 expression by the Microprocessor. RNA, 2009, 15, 1005-1011.
    • (2009) RNA , vol.15 , pp. 1005-1011
    • Triboulet, R.1    Chang, H.M.2    Lapierre, R.J.3    Gregory, R.I.4
  • 91
    • 34447115822 scopus 로고    scopus 로고
    • The multifunctional RNA-binding protein hnRNP A1 is required for processing of miR-18a
    • Guil, S.; Caceres, J. F. The multifunctional RNA-binding protein hnRNP A1 is required for processing of miR-18a. Nat. Struct. Mol. Biol., 2007, 14, 591-596.
    • (2007) Nat. Struct. Mol. Biol , vol.14 , pp. 591-596
    • Guil, S.1    Caceres, J.F.2
  • 92
    • 18144365478 scopus 로고    scopus 로고
    • MicroRNA biogenesis and cancer
    • Gregory, R. I.; Shiekhattar, R. MicroRNA biogenesis and cancer. Cancer Res., 2005, 65, 3509-3512.
    • (2005) Cancer Res , vol.65 , pp. 3509-3512
    • Gregory, R.I.1    Shiekhattar, R.2
  • 93
    • 0041691111 scopus 로고    scopus 로고
    • MicroRNAs and small interfering RNAs can inhibit mRNA expression by similar mechanisms
    • Zeng, Y.; Yi, R.; Cullen, B. R. MicroRNAs and small interfering RNAs can inhibit mRNA expression by similar mechanisms. Proc. Natl. Acad. Sci. USA, 2003, 100, 9779-9784.
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 9779-9784
    • Zeng, Y.1    Yi, R.2    Cullen, B.R.3
  • 94
    • 33846945735 scopus 로고    scopus 로고
    • Processing of intronic microRNAs
    • Kim, Y. K.; Kim, V. N. Processing of intronic microRNAs. EMBO J., 2007, 26, 775-783.
    • (2007) EMBO J , vol.26 , pp. 775-783
    • Kim, Y.K.1    Kim, V.N.2
  • 95
    • 7644237777 scopus 로고    scopus 로고
    • Intron-derived microRNAs--fine tuning of gene functions
    • Ying, S. Y.; Lin, S. L. Intron-derived microRNAs--fine tuning of gene functions. Gene, 2004, 342, 25-28.
    • (2004) Gene , vol.342 , pp. 25-28
    • Ying, S.Y.1    Lin, S.L.2
  • 96
    • 0141534299 scopus 로고    scopus 로고
    • A novel RNA splicing- mediated gene silencing mechanism potential for genome evolution
    • Lin, S. L.; Chang, D.; Wu, D. Y.; Ying, S. Y. A novel RNA splicing- mediated gene silencing mechanism potential for genome evolution. Biochem. Biophys. Res. Commun., 2003, 310, 754-760.
    • (2003) Biochem. Biophys. Res. Commun , vol.310 , pp. 754-760
    • Lin, S.L.1    Chang, D.2    Wu, D.Y.3    Ying, S.Y.4
  • 99
    • 34447097693 scopus 로고    scopus 로고
    • Intronic microRNA precursors that bypass Drosha processing
    • Ruby, J. G.; Jan, C. H.; Bartel, D. P. Intronic microRNA precursors that bypass Drosha processing. Nature, 2007, 448, 83-86.
    • (2007) Nature , vol.448 , pp. 83-86
    • Ruby, J.G.1    Jan, C.H.2    Bartel, D.P.3
  • 101
    • 1642499415 scopus 로고    scopus 로고
    • Exportin 5 is a RanGTP-dependent dsRNA-binding protein that mediates nuclear export of pre-miRNAs
    • Bohnsack, M. T.; Czaplinski, K.; Gorlich, D. Exportin 5 is a RanGTP-dependent dsRNA-binding protein that mediates nuclear export of pre-miRNAs. RNA, 2004, 10, 185-191.
    • (2004) RNA , vol.10 , pp. 185-191
    • Bohnsack, M.T.1    Czaplinski, K.2    Gorlich, D.3
  • 102
    • 34250677322 scopus 로고    scopus 로고
    • Substrate Selectivity of Exportin 5 and Dicer in the Biogenesis of MicroRNAs
    • Lund, E.; Dahlberg, J. E. Substrate Selectivity of Exportin 5 and Dicer in the Biogenesis of MicroRNAs. Cold Spring Harb. Symp. Quant. Biol., 2006, 71, 59-66.
    • (2006) Cold Spring Harb. Symp. Quant. Biol , vol.71 , pp. 59-66
    • Lund, E.1    Dahlberg, J.E.2
  • 104
    • 0347361541 scopus 로고    scopus 로고
    • Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs
    • Yi, R.; Qin, Y.; Macara, I. G.; Cullen, B. R. Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs. Genes Dev., 2003, 17, 3011-3016.
    • (2003) Genes Dev , vol.17 , pp. 3011-3016
    • Yi, R.1    Qin, Y.2    Macara, I.G.3    Cullen, B.R.4
  • 105
    • 4444230672 scopus 로고    scopus 로고
    • Structural requirements for pre-microRNA binding and nuclear export by Exportin 5
    • Zeng, Y.; Cullen, B. R. Structural requirements for pre-microRNA binding and nuclear export by Exportin 5. Nucleic Acids Res., 2004, 32, 4776-4785.
    • (2004) Nucleic Acids Res , vol.32 , pp. 4776-4785
    • Zeng, Y.1    Cullen, B.R.2
  • 106
    • 34447107760 scopus 로고    scopus 로고
    • The mirtron pathway generates microRNA-class regulatory RNAs in Drosophila
    • Okamura, K.; Hagen, J. W.; Duan, H.; Tyler, D. M.; Lai, E. C. The mirtron pathway generates microRNA-class regulatory RNAs in Drosophila. Cell, 2007, 130, 89-100.
    • (2007) Cell , vol.130 , pp. 89-100
    • Okamura, K.1    Hagen, J.W.2    Duan, H.3    Tyler, D.M.4    Lai, E.C.5
  • 107
    • 0036845374 scopus 로고    scopus 로고
    • Human Dicer preferentially cleaves dsRNAs at their termini without a requirement for ATP
    • Zhang, H.; Kolb, F. A.; Brondani, V.; Billy, E.; Filipowicz, W. Human Dicer preferentially cleaves dsRNAs at their termini without a requirement for ATP. EMBO J., 2002, 21, 5875-5885.
    • (2002) EMBO J , vol.21 , pp. 5875-5885
    • Zhang, H.1    Kolb, F.A.2    Brondani, V.3    Billy, E.4    Filipowicz, W.5
  • 109
    • 27144550559 scopus 로고    scopus 로고
    • TRBP, a regulator of cellular PKR and HIV-1 virus expression, interacts with Dicer and functions in RNA silencing
    • Haase, A. D.; Jaskiewicz, L.; Zhang, H.; Laine, S.; Sack, R.; Gatignol, A.; Filipowicz, W. TRBP, a regulator of cellular PKR and HIV-1 virus expression, interacts with Dicer and functions in RNA silencing. EMBO Rep., 2005, 6, 961-967.
    • (2005) EMBO Rep , vol.6 , pp. 961-967
    • Haase, A.D.1    Jaskiewicz, L.2    Zhang, H.3    Laine, S.4    Sack, R.5    Gatignol, A.6    Filipowicz, W.7
  • 110
    • 23044462450 scopus 로고    scopus 로고
    • Dicer-1 and R3D1-L catalyze microRNA maturation in Drosophila
    • Jiang, F.; Ye, X.; Liu, X.; Fincher, L.; McKearin, D.; Liu, Q. Dicer-1 and R3D1-L catalyze microRNA maturation in Drosophila. Genes Dev., 2005, 19, 1674-1679.
    • (2005) Genes Dev , vol.19 , pp. 1674-1679
    • Jiang, F.1    Ye, X.2    Liu, X.3    Fincher, L.4    McKearin, D.5    Liu, Q.6
  • 111
    • 1842816517 scopus 로고    scopus 로고
    • Distinct roles for Drosophila Dicer-1 and Dicer-2 in the siRNA/miRNA silencing pathways
    • Lee, Y. S.; Nakahara, K.; Pham, J. W.; Kim, K.; He, Z.; Sontheimer, E. J.; Carthew, R. W. Distinct roles for Drosophila Dicer-1 and Dicer-2 in the siRNA/miRNA silencing pathways. Cell, 2004, 117, 69-81.
    • (2004) Cell , vol.117 , pp. 69-81
    • Lee, Y.S.1    Nakahara, K.2    Pham, J.W.3    Kim, K.4    He, Z.5    Sontheimer, E.J.6    Carthew, R.W.7
  • 113
    • 3142613181 scopus 로고    scopus 로고
    • Single processing center models for human Dicer and bacterial RNase III
    • Zhang, H.; Kolb, F. A.; Jaskiewicz, L.; Westhof, E.; Filipowicz, W. Single processing center models for human Dicer and bacterial RNase III. Cell, 2004, 118, 57-68.
    • (2004) Cell , vol.118 , pp. 57-68
    • Zhang, H.1    Kolb, F.A.2    Jaskiewicz, L.3    Westhof, E.4    Filipowicz, W.5
  • 115
    • 0642345790 scopus 로고    scopus 로고
    • Structure and conserved RNA binding of the PAZ domain
    • Yan, K. S.; Yan, S.; Farooq, A.; Han, A.; Zeng, L.; Zhou, M. M. Structure and conserved RNA binding of the PAZ domain. Nature, 2003, 426, 468-474.
    • (2003) Nature , vol.426 , pp. 468-474
    • Yan, K.S.1    Yan, S.2    Farooq, A.3    Han, A.4    Zeng, L.5    Zhou, M.M.6
  • 116
    • 33846188098 scopus 로고    scopus 로고
    • MicroRNAs as oncogenes and tumor suppressors
    • Zhang, B.; Pan, X.; Cobb, G. P.; Anderson, T. A. MicroRNAs as oncogenes and tumor suppressors. Dev. Biol., 2007, 302, 1-12.
    • (2007) Dev. Biol , vol.302 , pp. 1-12
    • Zhang, B.1    Pan, X.2    Cobb, G.P.3    Anderson, T.A.4
  • 117
    • 0035807818 scopus 로고    scopus 로고
    • Specific interference with gene expression induced by long, double- stranded RNA in mouse embryonal teratocarcinoma cell lines
    • Billy, E.; Brondani, V.; Zhang, H.; Muller, U.; Filipowicz, W. Specific interference with gene expression induced by long, double- stranded RNA in mouse embryonal teratocarcinoma cell lines. Proc. Natl. Acad. Sci. USA, 2001, 98, 14428-14433.
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 14428-14433
    • Billy, E.1    Brondani, V.2    Zhang, H.3    Muller, U.4    Filipowicz, W.5
  • 119
    • 32544460452 scopus 로고    scopus 로고
    • The role of PACT in the RNA silencing pathway
    • Lee, Y.; Hur, I.; Park, S. Y.; Kim, Y. K.; Suh, M. R.; Kim, V. N. The role of PACT in the RNA silencing pathway. EMBO J., 2006, 25, 522-532.
    • (2006) EMBO J , vol.25 , pp. 522-532
    • Lee, Y.1    Hur, I.2    Park, S.Y.3    Kim, Y.K.4    Suh, M.R.5    Kim, V.N.6
  • 120
    • 36849048778 scopus 로고    scopus 로고
    • Dual role for argonautes in microRNA processing and posttranscriptional regulation of microRNA expression
    • Diederichs, S.; Haber, D. A. Dual role for argonautes in microRNA processing and posttranscriptional regulation of microRNA expression. Cell, 2007, 131, 1097-1108.
    • (2007) Cell , vol.131 , pp. 1097-1108
    • Diederichs, S.1    Haber, D.A.2
  • 122
    • 4444302947 scopus 로고    scopus 로고
    • Crystal structure of Argonaute and its implications for RISC slicer activity
    • Song, J. J.; Smith, S. K.; Hannon, G. J.; Joshua-Tor, L. Crystal structure of Argonaute and its implications for RISC slicer activity. Science, 2004, 305, 1434-1437.
    • (2004) Science , vol.305 , pp. 1434-1437
    • Song, J.J.1    Smith, S.K.2    Hannon, G.J.3    Joshua-Tor, L.4
  • 125
    • 27744537851 scopus 로고    scopus 로고
    • Human RISC couples microRNA biogenesis and posttranscriptional gene silencing
    • Gregory, R. I.; Chendrimada, T. P.; Cooch, N.; Shiekhattar, R. Human RISC couples microRNA biogenesis and posttranscriptional gene silencing. Cell, 2005, 123, 631-640.
    • (2005) Cell , vol.123 , pp. 631-640
    • Gregory, R.I.1    Chendrimada, T.P.2    Cooch, N.3    Shiekhattar, R.4
  • 126
    • 29144431656 scopus 로고    scopus 로고
    • A human, ATP-independent, RISC assembly machine fueled by pre-miRNA
    • Maniataki, E.; Mourelatos, Z. A human, ATP-independent, RISC assembly machine fueled by pre-miRNA. Genes Dev., 2005, 19, 2979-2990.
    • (2005) Genes Dev , vol.19 , pp. 2979-2990
    • Maniataki, E.1    Mourelatos, Z.2
  • 127
    • 27344452745 scopus 로고    scopus 로고
    • Mammalian Dicer finds a partner
    • Rossi, J. J. Mammalian Dicer finds a partner. EMBO Rep., 2005, 6, 927-929.
    • (2005) EMBO Rep , vol.6 , pp. 927-929
    • Rossi, J.J.1
  • 129
    • 0035823590 scopus 로고    scopus 로고
    • Two dimerization domains in the transactivation response RNA-binding protein (TRBP) individually reverse the protein kinase R inhibition of HIV-1 long terminal repeat expression
    • Daher, A.; Longuet, M.; Dorin, D.; Bois, F.; Segeral, E.; Bannwarth, S.; Battisti, P. L.; Purcell, D. F.; Benarous, R.; Vaquero, C.; Meurs, E. F.; Gatignol, A. Two dimerization domains in the transactivation response RNA-binding protein (TRBP) individually reverse the protein kinase R inhibition of HIV-1 long terminal repeat expression. J. Biol. Chem., 2001, 276, 33899-33905.
    • (2001) J. Biol. Chem , vol.276 , pp. 33899-33905
    • Daher, A.1    Longuet, M.2    Dorin, D.3    Bois, F.4    Segeral, E.5    Bannwarth, S.6    Battisti, P.L.7    Purcell, D.F.8    Benarous, R.9    Vaquero, C.10    Meurs, E.F.11    Gatignol, A.12
  • 130
    • 0142247418 scopus 로고    scopus 로고
    • The carboxy-terminal, M3 motifs of PACT and TRBP have opposite effects on PKR activity
    • Gupta, V.; Huang, X.; Patel, R. C. The carboxy-terminal, M3 motifs of PACT and TRBP have opposite effects on PKR activity. Virology, 2003, 315, 283-291.
    • (2003) Virology , vol.315 , pp. 283-291
    • Gupta, V.1    Huang, X.2    Patel, R.C.3
  • 131
    • 0035012516 scopus 로고    scopus 로고
    • Modular structure of PACT: Distinct domains for binding and activating PKR
    • Peters, G. A.; Hartmann, R.; Qin, J.; Sen, G. C. Modular structure of PACT: distinct domains for binding and activating PKR. Mol. Cell. Biol., 2001, 21, 1908-1920.
    • (2001) Mol. Cell. Biol , vol.21 , pp. 1908-1920
    • Peters, G.A.1    Hartmann, R.2    Qin, J.3    Sen, G.C.4
  • 132
    • 0032480017 scopus 로고    scopus 로고
    • PACT, a protein activator of the interferoninduced protein kinase, PKR
    • Patel, R. C.; Sen, G. C. PACT, a protein activator of the interferoninduced protein kinase, PKR. EMBO J., 1998, 17, 4379-4390.
    • (1998) EMBO J , vol.17 , pp. 4379-4390
    • Patel, R.C.1    Sen, G.C.2
  • 133
    • 34347225099 scopus 로고    scopus 로고
    • The dsRNA protein kinase PKR: Virus and cell control
    • Garcia, M. A.; Meurs, E. F.; Esteban, M. The dsRNA protein kinase PKR: virus and cell control. Biochimie, 2007, 89, 799-811.
    • (2007) Biochimie , vol.89 , pp. 799-811
    • Garcia, M.A.1    Meurs, E.F.2    Esteban, M.3
  • 135
    • 0034825325 scopus 로고    scopus 로고
    • Mechanism of activation of the double-stranded-RNA-dependent protein kinase, PKR: Role of dimerization and cellular localization in the stimulation of PKR phosphorylation of eukaryotic initiation factor-2 (eIF2)
    • Vattem, K. M.; Staschke, K. A.; Wek, R. C. Mechanism of activation of the double-stranded-RNA-dependent protein kinase, PKR: role of dimerization and cellular localization in the stimulation of PKR phosphorylation of eukaryotic initiation factor-2 (eIF2). Eur. J. Biochem., 2001, 268, 3674-3684.
    • (2001) Eur. J. Biochem , vol.268 , pp. 3674-3684
    • Vattem, K.M.1    Staschke, K.A.2    Wek, R.C.3
  • 137
    • 0035955361 scopus 로고    scopus 로고
    • An abundant class of tiny RNAs with probable regulatory roles in Caenorhabditis elegans
    • Lau, N. C.; Lim, L. P.; Weinstein, E. G.; Bartel, D. P. An abundant class of tiny RNAs with probable regulatory roles in Caenorhabditis elegans. Science, 2001, 294, 858-862.
    • (2001) Science , vol.294 , pp. 858-862
    • Lau, N.C.1    Lim, L.P.2    Weinstein, E.G.3    Bartel, D.P.4
  • 138
    • 2142654329 scopus 로고    scopus 로고
    • MicroRNA-directed cleavage of HOXB8 mRNA
    • Yekta, S.; Shih, I. H.; Bartel, D. P. MicroRNA-directed cleavage of HOXB8 mRNA. Science, 2004, 304, 594-596.
    • (2004) Science , vol.304 , pp. 594-596
    • Yekta, S.1    Shih, I.H.2    Bartel, D.P.3
  • 139
    • 27744590896 scopus 로고    scopus 로고
    • Passenger-strand cleavage facilitates assembly of siRNA into Ago2-containing RNAi enzyme complexes
    • Matranga, C.; Tomari, Y.; Shin, C.; Bartel, D. P.; Zamore, P. D. Passenger-strand cleavage facilitates assembly of siRNA into Ago2-containing RNAi enzyme complexes. Cell, 2005, 123, 607-620.
    • (2005) Cell , vol.123 , pp. 607-620
    • Matranga, C.1    Tomari, Y.2    Shin, C.3    Bartel, D.P.4    Zamore, P.D.5
  • 140
    • 27744506761 scopus 로고    scopus 로고
    • Argonaute2 cleaves the anti-guide strand of siRNA during RISC activation
    • Rand, T. A.; Petersen, S.; Du, F.; Wang, X. Argonaute2 cleaves the anti-guide strand of siRNA during RISC activation. Cell, 2005, 123, 621-629.
    • (2005) Cell , vol.123 , pp. 621-629
    • Rand, T.A.1    Petersen, S.2    Du, F.3    Wang, X.4
  • 141
    • 0142165224 scopus 로고    scopus 로고
    • Functional siRNAs and miRNAs exhibit strand bias
    • Khvorova, A.; Reynolds, A.; Jayasena, S. D. Functional siRNAs and miRNAs exhibit strand bias. Cell, 2003, 115, 209-216.
    • (2003) Cell , vol.115 , pp. 209-216
    • Khvorova, A.1    Reynolds, A.2    Jayasena, S.D.3
  • 142
  • 143
    • 0035955374 scopus 로고    scopus 로고
    • Identification of novel genes coding for small expressed RNAs
    • Lagos-Quintana, M.; Rauhut, R.; Lendeckel, W.; Tuschl, T. Identification of novel genes coding for small expressed RNAs. Science, 2001, 294, 853-858.
    • (2001) Science , vol.294 , pp. 853-858
    • Lagos-Quintana, M.1    Rauhut, R.2    Lendeckel, W.3    Tuschl, T.4
  • 145
    • 0036074161 scopus 로고    scopus 로고
    • RNA interference in human cells is restricted to the cytoplasm
    • Zeng, Y.; Cullen, B. R. RNA interference in human cells is restricted to the cytoplasm. RNA, 2002, 8, 855-860.
    • (2002) RNA , vol.8 , pp. 855-860
    • Zeng, Y.1    Cullen, B.R.2
  • 146
    • 12544258104 scopus 로고    scopus 로고
    • MicroRNA biogenesis: Drosha can't cut it without a partner
    • Tomari, Y.; Zamore, P. D. MicroRNA biogenesis: drosha can't cut it without a partner. Curr. Biol., 2005, 15, R61-64.
    • (2005) Curr. Biol , vol.15
    • Tomari, Y.1    Zamore, P.D.2
  • 147
    • 33645763485 scopus 로고    scopus 로고
    • Cleavage of the siRNA passenger strand during RISC assembly in human cells
    • Leuschner, P. J.; Ameres, S. L.; Kueng, S.; Martinez, J. Cleavage of the siRNA passenger strand during RISC assembly in human cells. EMBO Rep., 2006, 7, 314-320.
    • (2006) EMBO Rep , vol.7 , pp. 314-320
    • Leuschner, P.J.1    Ameres, S.L.2    Kueng, S.3    Martinez, J.4
  • 149
    • 0036529621 scopus 로고    scopus 로고
    • Comparative genomics and evolution of proteins involved in RNA metabolism
    • Anantharaman, V.; Koonin, E. V.; Aravind, L. Comparative genomics and evolution of proteins involved in RNA metabolism. Nucleic Acids Res., 2002, 30, 1427-1464.
    • (2002) Nucleic Acids Res , vol.30 , pp. 1427-1464
    • Anantharaman, V.1    Koonin, E.V.2    Aravind, L.3
  • 150
    • 34248576287 scopus 로고    scopus 로고
    • RNA helicase A interacts with RISC in human cells and functions in RISC loading
    • Robb, G. B.; Rana, T. M. RNA helicase A interacts with RISC in human cells and functions in RISC loading. Mol. Cell, 2007, 26, 523-537.
    • (2007) Mol. Cell , vol.26 , pp. 523-537
    • Robb, G.B.1    Rana, T.M.2
  • 151
    • 0038024236 scopus 로고    scopus 로고
    • The human DDX and DHX gene families of putative RNA helicases
    • Abdelhaleem, M.; Maltais, L.; Wain, H. The human DDX and DHX gene families of putative RNA helicases. Genomics, 2003, 81, 618-622.
    • (2003) Genomics , vol.81 , pp. 618-622
    • Abdelhaleem, M.1    Maltais, L.2    Wain, H.3
  • 152
    • 0026726096 scopus 로고
    • A new RNA helicase isolated from HeLa cells that catalytically translocates in the 3' to 5' direction
    • Lee, C. G.; Hurwitz, J. A new RNA helicase isolated from HeLa cells that catalytically translocates in the 3' to 5' direction. J. Biol. Chem., 1992, 267, 4398-4407.
    • (1992) J. Biol. Chem , vol.267 , pp. 4398-4407
    • Lee, C.G.1    Hurwitz, J.2
  • 153
    • 24744471193 scopus 로고    scopus 로고
    • Nuclear DNA helicase II (RNA helicase A) interacts with Werner syndrome helicase and stimulates its exonuclease activity
    • Friedemann, J.; Grosse, F.; Zhang, S. Nuclear DNA helicase II (RNA helicase A) interacts with Werner syndrome helicase and stimulates its exonuclease activity. J. Biol. Chem., 2005, 280, 31303-31313.
    • (2005) J. Biol. Chem , vol.280 , pp. 31303-31313
    • Friedemann, J.1    Grosse, F.2    Zhang, S.3
  • 157
    • 1642374097 scopus 로고    scopus 로고
    • Specificity of microRNA target selection in translational repression
    • Doench, J. G.; Sharp, P. A. Specificity of microRNA target selection in translational repression. Genes Dev., 2004, 18, 504-511.
    • (2004) Genes Dev , vol.18 , pp. 504-511
    • Doench, J.G.1    Sharp, P.A.2
  • 161
    • 0142173075 scopus 로고    scopus 로고
    • Small RNAs with imperfect match to endogenous mRNA repress translation. Implications for off-target activity of small inhibitory RNA in mammalian cells
    • Saxena, S.; Jonsson, Z. O.; Dutta, A. Small RNAs with imperfect match to endogenous mRNA repress translation. Implications for off-target activity of small inhibitory RNA in mammalian cells. J. Biol. Chem., 2003, 278, 44312-44319.
    • (2003) J. Biol. Chem , vol.278 , pp. 44312-44319
    • Saxena, S.1    Jonsson, Z.O.2    Dutta, A.3
  • 164
    • 2442566370 scopus 로고    scopus 로고
    • Cytoplasmic foci are sites of mRNA decay in human cells
    • Cougot, N.; Babajko, S.; Seraphin, B. Cytoplasmic foci are sites of mRNA decay in human cells. J. Cell Biol., 2004, 165, 31-40.
    • (2004) J. Cell Biol , vol.165 , pp. 31-40
    • Cougot, N.1    Babajko, S.2    Seraphin, B.3
  • 165
    • 27144515901 scopus 로고    scopus 로고
    • Movement of eukaryotic mRNAs between polysomes and cytoplasmic processing bodies
    • Brengues, M.; Teixeira, D.; Parker, R. Movement of eukaryotic mRNAs between polysomes and cytoplasmic processing bodies. Science, 2005, 310, 486-489.
    • (2005) Science , vol.310 , pp. 486-489
    • Brengues, M.1    Teixeira, D.2    Parker, R.3
  • 166
    • 0037968357 scopus 로고    scopus 로고
    • Decapping and decay of messenger RNA occur in cytoplasmic processing bodies
    • Sheth, U.; Parker, R. Decapping and decay of messenger RNA occur in cytoplasmic processing bodies. Science, 2003, 300, 805-808.
    • (2003) Science , vol.300 , pp. 805-808
    • Sheth, U.1    Parker, R.2
  • 168
    • 0141856112 scopus 로고    scopus 로고
    • The GW182 protein colocalizes with mRNA degradation associated proteins hDcp1 and hLSm4 in cytoplasmic GW bodies
    • Eystathioy, T.; Jakymiw, A.; Chan, E. K.; Seraphin, B.; Cougot, N.; Fritzler, M. J. The GW182 protein colocalizes with mRNA degradation associated proteins hDcp1 and hLSm4 in cytoplasmic GW bodies. RNA, 2003, 9, 1171-1173.
    • (2003) RNA , vol.9 , pp. 1171-1173
    • Eystathioy, T.1    Jakymiw, A.2    Chan, E.K.3    Seraphin, B.4    Cougot, N.5    Fritzler, M.J.6
  • 169
    • 33645119514 scopus 로고    scopus 로고
    • MicroRNAs direct rapid deadenylation of mRNA
    • Wu, L.; Fan, J.; Belasco, J. G. MicroRNAs direct rapid deadenylation of mRNA. Proc. Natl. Acad. Sci. USA, 2006, 103, 4034-4039.
    • (2006) Proc. Natl. Acad. Sci. USA , vol.103 , pp. 4034-4039
    • Wu, L.1    Fan, J.2    Belasco, J.G.3
  • 170
    • 0037121926 scopus 로고    scopus 로고
    • Human Dcp2: A catalytically active mRNA decapping enzyme located in specific cytoplasmic structures
    • van Dijk, E.; Cougot, N.; Meyer, S.; Babajko, S.; Wahle, E.; Seraphin, B. Human Dcp2: a catalytically active mRNA decapping enzyme located in specific cytoplasmic structures. EMBO J., 2002, 21, 6915-6924.
    • (2002) EMBO J , vol.21 , pp. 6915-6924
    • van Dijk, E.1    Cougot, N.2    Meyer, S.3    Babajko, S.4    Wahle, E.5    Seraphin, B.6
  • 171
    • 25144482816 scopus 로고    scopus 로고
    • General translational repression by activators of mRNA decapping
    • Coller, J.; Parker, R. General translational repression by activators of mRNA decapping. Cell, 2005, 122, 875-886.
    • (2005) Cell , vol.122 , pp. 875-886
    • Coller, J.1    Parker, R.2
  • 173
    • 1242318826 scopus 로고    scopus 로고
    • Sequencespecific inhibition of microRNA- and siRNA-induced RNA silencing
    • Meister, G.; Landthaler, M.; Dorsett, Y.; Tuschl, T. Sequencespecific inhibition of microRNA- and siRNA-induced RNA silencing. RNA, 2004, 10, 544-550.
    • (2004) RNA , vol.10 , pp. 544-550
    • Meister, G.1    Landthaler, M.2    Dorsett, Y.3    Tuschl, T.4
  • 174
    • 33644768174 scopus 로고    scopus 로고
    • Control of translation and mRNA degradation by miRNAs and siRNAs
    • Valencia-Sanchez, M. A.; Liu, J.; Hannon, G. J.; Parker, R. Control of translation and mRNA degradation by miRNAs and siRNAs. Genes Dev., 2006, 20, 515-524.
    • (2006) Genes Dev , vol.20 , pp. 515-524
    • Valencia-Sanchez, M.A.1    Liu, J.2    Hannon, G.J.3    Parker, R.4
  • 175
    • 33845353746 scopus 로고    scopus 로고
    • Evidence that microRNAs are associated with translating messenger RNAs in human cells
    • Maroney, P. A.; Yu, Y.; Fisher, J.; Nilsen, T. W. Evidence that microRNAs are associated with translating messenger RNAs in human cells. Nat. Struct. Mol. Biol., 2006, 13, 1102-1107.
    • (2006) Nat. Struct. Mol. Biol , vol.13 , pp. 1102-1107
    • Maroney, P.A.1    Yu, Y.2    Fisher, J.3    Nilsen, T.W.4
  • 177
    • 33845354027 scopus 로고    scopus 로고
    • Human let-7a miRNA blocks protein production on actively translating polyribosomes
    • Nottrott, S.; Simard, M. J.; Richter, J. D. Human let-7a miRNA blocks protein production on actively translating polyribosomes. Nat. Struct. Mol. Biol., 2006, 13, 1108-1114.
    • (2006) Nat. Struct. Mol. Biol , vol.13 , pp. 1108-1114
    • Nottrott, S.1    Simard, M.J.2    Richter, J.D.3
  • 178
    • 4444363152 scopus 로고    scopus 로고
    • MicroRNA control of PHABULOSA in leaf development: Importance of pairing to the microRNA 5' region
    • Mallory, A. C.; Reinhart, B. J.; Jones-Rhoades, M. W.; Tang, G.; Zamore, P. D.; Barton, M. K.; Bartel, D. P. MicroRNA control of PHABULOSA in leaf development: importance of pairing to the microRNA 5' region. EMBO J., 2004, 23, 3356-3364.
    • (2004) EMBO J , vol.23 , pp. 3356-3364
    • Mallory, A.C.1    Reinhart, B.J.2    Jones-Rhoades, M.W.3    Tang, G.4    Zamore, P.D.5    Barton, M.K.6    Bartel, D.P.7
  • 179
    • 1542351278 scopus 로고    scopus 로고
    • MicroRNAs: Something important between the genes
    • Mallory, A. C.; Vaucheret, H. MicroRNAs: something important between the genes. Curr. Opin. Plant. Biol., 2004, 7, 120-125.
    • (2004) Curr. Opin. Plant. Biol , vol.7 , pp. 120-125
    • Mallory, A.C.1    Vaucheret, H.2
  • 181
    • 0742288008 scopus 로고    scopus 로고
    • The enzymes and control of eukaryotic mRNA turnover
    • Parker, R.; Song, H. The enzymes and control of eukaryotic mRNA turnover. Nat. Struct. Mol. Biol., 2004, 11, 121-127.
    • (2004) Nat. Struct. Mol. Biol , vol.11 , pp. 121-127
    • Parker, R.1    Song, H.2
  • 182
    • 3943051423 scopus 로고    scopus 로고
    • Eukaryotic mRNA decapping
    • Coller, J.; Parker, R. Eukaryotic mRNA decapping. Annu. Rev. Biochem., 2004, 73, 861-890.
    • (2004) Annu. Rev. Biochem , vol.73 , pp. 861-890
    • Coller, J.1    Parker, R.2
  • 183
    • 28344440823 scopus 로고    scopus 로고
    • MicroRNA function: Multiple mechanisms for a tiny RNA?
    • Pillai, R. S. MicroRNA function: multiple mechanisms for a tiny RNA? RNA, 2005, 11, 1753-1761.
    • (2005) RNA , vol.11 , pp. 1753-1761
    • Pillai, R.S.1
  • 185
    • 4644310115 scopus 로고    scopus 로고
    • Tethering of human Ago proteins to mRNA mimics the miRNA-mediated repression of protein synthesis
    • Pillai, R. S.; Artus, C. G.; Filipowicz, W. Tethering of human Ago proteins to mRNA mimics the miRNA-mediated repression of protein synthesis. RNA, 2004, 10, 1518-1525.
    • (2004) RNA , vol.10 , pp. 1518-1525
    • Pillai, R.S.1    Artus, C.G.2    Filipowicz, W.3
  • 186
    • 0017339341 scopus 로고
    • The mechanism of protein synthesisinitiation, elongation and termination in translation of genetic messeges
    • Richter, D.; Isono, K. The mechanism of protein synthesisinitiation, elongation and termination in translation of genetic messeges. Curr. Top. Microbiol. Immunol., 1977, 76, 83-125.
    • (1977) Curr. Top. Microbiol. Immunol , vol.76 , pp. 83-125
    • Richter, D.1    Isono, K.2
  • 187
    • 32444436121 scopus 로고    scopus 로고
    • Short RNAs repress translation after initiation in mammalian cells
    • Petersen, C. P.; Bordeleau, M. E.; Pelletier, J.; Sharp, P. A. Short RNAs repress translation after initiation in mammalian cells. Mol. Cell, 2006, 21, 533-542.
    • (2006) Mol. Cell , vol.21 , pp. 533-542
    • Petersen, C.P.1    Bordeleau, M.E.2    Pelletier, J.3    Sharp, P.A.4
  • 189
    • 22144478256 scopus 로고    scopus 로고
    • MicroRNA-dependent localization of targeted mRNAs to mammalian P-bodies
    • Liu, J.; Valencia-Sanchez, M. A.; Hannon, G. J.; Parker, R. MicroRNA-dependent localization of targeted mRNAs to mammalian P-bodies. Nat. Cell Biol., 2005, 7, 719-723.
    • (2005) Nat. Cell Biol , vol.7 , pp. 719-723
    • Liu, J.1    Valencia-Sanchez, M.A.2    Hannon, G.J.3    Parker, R.4
  • 192
    • 17844371700 scopus 로고    scopus 로고
    • A role for eIF4E and eIF4E-transporter in targeting mRNPs to mammalian processing bodies
    • Andrei, M. A.; Ingelfinger, D.; Heintzmann, R.; Achsel, T.; Rivera-Pomar, R.; Luhrmann, R. A role for eIF4E and eIF4E-transporter in targeting mRNPs to mammalian processing bodies. RNA, 2005, 11, 717-727.
    • (2005) RNA , vol.11 , pp. 717-727
    • Andrei, M.A.1    Ingelfinger, D.2    Heintzmann, R.3    Achsel, T.4    Rivera-Pomar, R.5    Luhrmann, R.6
  • 194
    • 15444379718 scopus 로고    scopus 로고
    • Processing bodies require RNA for assembly and contain nontranslating mRNAs
    • Teixeira, D.; Sheth, U.; Valencia-Sanchez, M. A.; Brengues, M.; Parker, R. Processing bodies require RNA for assembly and contain nontranslating mRNAs. RNA, 2005, 11, 371-382.
    • (2005) RNA , vol.11 , pp. 371-382
    • Teixeira, D.1    Sheth, U.2    Valencia-Sanchez, M.A.3    Brengues, M.4    Parker, R.5
  • 196
    • 0037013898 scopus 로고    scopus 로고
    • The DEAD box protein Dhh1 stimulates the decapping enzyme Dcp1
    • Fischer, N.; Weis, K. The DEAD box protein Dhh1 stimulates the decapping enzyme Dcp1. EMBO J., 2002, 21, 2788-2797.
    • (2002) EMBO J , vol.21 , pp. 2788-2797
    • Fischer, N.1    Weis, K.2
  • 197
    • 0035674477 scopus 로고    scopus 로고
    • The DEAD box helicase, Dhh1p, functions in mRNA decapping and interacts with both the decapping and deadenylase complexes
    • Coller, J. M.; Tucker, M.; Sheth, U.; Valencia-Sanchez, M. A.; Parker, R. The DEAD box helicase, Dhh1p, functions in mRNA decapping and interacts with both the decapping and deadenylase complexes. RNA, 2001, 7, 1717-1727.
    • (2001) RNA , vol.7 , pp. 1717-1727
    • Coller, J.M.1    Tucker, M.2    Sheth, U.3    Valencia-Sanchez, M.A.4    Parker, R.5
  • 198
    • 69949117622 scopus 로고    scopus 로고
    • Multivesicular bodies associate with components of miRNA effector complexes and modulate miRNA activity
    • Gibbings, D. J.; Ciaudo, C.; Erhardt, M.; Voinnet, O. Multivesicular bodies associate with components of miRNA effector complexes and modulate miRNA activity. Nat. Cell Biol., 2009, 11, 1143-1149.
    • (2009) Nat. Cell Biol , vol.11 , pp. 1143-1149
    • Gibbings, D.J.1    Ciaudo, C.2    Erhardt, M.3    Voinnet, O.4
  • 199
    • 38449123517 scopus 로고    scopus 로고
    • Mammalian stress granules and processing bodies
    • Kedersha, N.; Anderson, P. Mammalian stress granules and processing bodies. Methods Enzymol., 2007, 431, 61-81.
    • (2007) Methods Enzymol , vol.431 , pp. 61-81
    • Kedersha, N.1    Anderson, P.2
  • 200
    • 0033611157 scopus 로고    scopus 로고
    • RNAbinding proteins TIA-1 and TIAR link the phosphorylation of eIF-2 alpha to the assembly of mammalian stress granules
    • Kedersha, N. L.; Gupta, M.; Li, W.; Miller, I.; Anderson, P. RNAbinding proteins TIA-1 and TIAR link the phosphorylation of eIF-2 alpha to the assembly of mammalian stress granules. J. Cell Biol., 1999, 147, 1431-1442.
    • (1999) J. Cell Biol , vol.147 , pp. 1431-1442
    • Kedersha, N.L.1    Gupta, M.2    Li, W.3    Miller, I.4    Anderson, P.5
  • 201
    • 33751225043 scopus 로고    scopus 로고
    • MicroRNA-Mediated Silencing Inside PBodies
    • Chan, S. P.; Slack, F. J. MicroRNA-Mediated Silencing Inside PBodies. RNA Biol., 2006, 3, 97-100.
    • (2006) RNA Biol , vol.3 , pp. 97-100
    • Chan, S.P.1    Slack, F.J.2
  • 202
    • 33847417585 scopus 로고    scopus 로고
    • Bodies and the control of mRNA translation and degradation
    • Parker, R.; Sheth, U. P Bodies and the control of mRNA translation and degradation. Mol. Cell, 2007, 25, 635-646.
    • (2007) Mol. Cell , vol.25 , pp. 635-646
    • Parker, R.1    Sheth, U.P.2
  • 206
    • 20444427566 scopus 로고    scopus 로고
    • Argonaute 2/RISC resides in sites of mammalian mRNA decay known as cytoplasmic bodies
    • Sen, G. L.; Blau, H. M. Argonaute 2/RISC resides in sites of mammalian mRNA decay known as cytoplasmic bodies. Nat. Cell Biol., 2005, 7, 633-636.
    • (2005) Nat. Cell Biol , vol.7 , pp. 633-636
    • Sen, G.L.1    Blau, H.M.2
  • 207
    • 10944256057 scopus 로고    scopus 로고
    • GW182 is critical for the stability of GW bodies expressed during the cell cycle and cell proliferation
    • Yang, Z.; Jakymiw, A.; Wood, M. R.; Eystathioy, T.; Rubin, R. L.; Fritzler, M. J.; Chan, E. K. GW182 is critical for the stability of GW bodies expressed during the cell cycle and cell proliferation. J. Cell Sci., 2004, 117, 5567-5578.
    • (2004) J. Cell Sci , vol.117 , pp. 5567-5578
    • Yang, Z.1    Jakymiw, A.2    Wood, M.R.3    Eystathioy, T.4    Rubin, R.L.5    Fritzler, M.J.6    Chan, E.K.7
  • 208
    • 0036223709 scopus 로고    scopus 로고
    • A phosphorylated cytoplasmic autoantigen, GW182, associates with a unique population of human mRNAs within novel cytoplasmic speckles
    • Eystathioy, T.; Chan, E. K.; Tenenbaum, S. A.; Keene, J. D.; Griffith, K.; Fritzler, M. J. A phosphorylated cytoplasmic autoantigen, GW182, associates with a unique population of human mRNAs within novel cytoplasmic speckles. Mol. Biol. Cell, 2002, 13, 1338-1351.
    • (2002) Mol. Biol. Cell , vol.13 , pp. 1338-1351
    • Eystathioy, T.1    Chan, E.K.2    Tenenbaum, S.A.3    Keene, J.D.4    Griffith, K.5    Fritzler, M.J.6
  • 209
    • 33746055678 scopus 로고    scopus 로고
    • MRNA degradation by miRNAs and GW182 requires both CCR4:NOT deadenylase and DCP1:DCP2 decapping complexes
    • Behm-Ansmant, I.; Rehwinkel, J.; Doerks, T.; Stark, A.; Bork, P.; Izaurralde, E. MRNA degradation by miRNAs and GW182 requires both CCR4:NOT deadenylase and DCP1:DCP2 decapping complexes. Genes Dev., 2006, 20, 1885-1898.
    • (2006) Genes Dev , vol.20 , pp. 1885-1898
    • Behm-Ansmant, I.1    Rehwinkel, J.2    Doerks, T.3    Stark, A.4    Bork, P.5    Izaurralde, E.6
  • 210
    • 34250653704 scopus 로고    scopus 로고
    • MicroRNAs Silence Gene Expression by Repressing Protein Expression and/or by Promoting mRNA Decay
    • Behm-Ansmant, I.; Rehwinkel, J.; Izaurralde, E. MicroRNAs Silence Gene Expression by Repressing Protein Expression and/or by Promoting mRNA Decay. Cold Spring Harb. Symp. Quant. Biol., 2006, 71, 523-530.
    • (2006) Cold Spring Harb. Symp. Quant. Biol , vol.71 , pp. 523-530
    • Behm-Ansmant, I.1    Rehwinkel, J.2    Izaurralde, E.3
  • 211
    • 34548490990 scopus 로고    scopus 로고
    • GW182 family proteins are crucial for microRNA-mediated gene silencing
    • Ding, L.; Han, M. GW182 family proteins are crucial for microRNA-mediated gene silencing. Trends Cell Biol., 2007, 17, 411-416.
    • (2007) Trends Cell Biol , vol.17 , pp. 411-416
    • Ding, L.1    Han, M.2
  • 212
    • 33751348560 scopus 로고    scopus 로고
    • Detection of the argonaute protein Ago2 and microRNAs in the RNA induced silencing complex (RISC) using a monoclonal antibody
    • Ikeda, K.; Satoh, M.; Pauley, K. M.; Fritzler, M. J.; Reeves, W. H.; Chan, E. K. Detection of the argonaute protein Ago2 and microRNAs in the RNA induced silencing complex (RISC) using a monoclonal antibody. J. Immunol. Methods, 2006, 317, 38-44.
    • (2006) J. Immunol. Methods , vol.317 , pp. 38-44
    • Ikeda, K.1    Satoh, M.2    Pauley, K.M.3    Fritzler, M.J.4    Reeves, W.H.5    Chan, E.K.6
  • 213
    • 33745894330 scopus 로고    scopus 로고
    • Translation repression in human cells by microRNA-induced gene silencing requires RCK/p54
    • Chu, C. Y.; Rana, T. M. Translation repression in human cells by microRNA-induced gene silencing requires RCK/p54. PLoS Biol., 2006, 4, e210.
    • (2006) PLoS Biol , vol.4
    • Chu, C.Y.1    Rana, T.M.2
  • 215
    • 0036792769 scopus 로고    scopus 로고
    • Fragile X-related protein and VIG associate with the RNA interference machinery
    • Caudy, A. A.; Myers, M.; Hannon, G. J.; Hammond, S. M. Fragile X-related protein and VIG associate with the RNA interference machinery. Genes Dev., 2002, 16, 2491-2496.
    • (2002) Genes Dev , vol.16 , pp. 2491-2496
    • Caudy, A.A.1    Myers, M.2    Hannon, G.J.3    Hammond, S.M.4
  • 216
    • 34250613502 scopus 로고    scopus 로고
    • MiRNA in disease and therapeutic development
    • Tanaka, Y.; Kozu, T. MiRNA in disease and therapeutic development. Tanpakushitsu Kakusan Koso, 2006, 51, 2509-2514.
    • (2006) Tanpakushitsu Kakusan Koso , vol.51 , pp. 2509-2514
    • Tanaka, Y.1    Kozu, T.2
  • 218
    • 11844281461 scopus 로고    scopus 로고
    • Mammalian poly(A)-binding protein is a eukaryotic translation initiation factor, which acts via multiple mechanisms
    • Kahvejian, A.; Svitkin, Y. V.; Sukarieh, R.; M'Boutchou, M. N.; Sonenberg, N. Mammalian poly(A)-binding protein is a eukaryotic translation initiation factor, which acts via multiple mechanisms. Genes Dev., 2005, 19, 104-113.
    • (2005) Genes Dev , vol.19 , pp. 104-113
    • Kahvejian, A.1    Svitkin, Y.V.2    Sukarieh, R.3    M'Boutchou, M.N.4    Sonenberg, N.5
  • 219
    • 33744973775 scopus 로고    scopus 로고
    • Relief of microRNA-mediated translational repression in human cells subjected to stress
    • Bhattacharyya, S. N.; Habermacher, R.; Martine, U.; Closs, E. I.; Filipowicz, W. Relief of microRNA-mediated translational repression in human cells subjected to stress. Cell, 2006, 125, 1111-1124.
    • (2006) Cell , vol.125 , pp. 1111-1124
    • Bhattacharyya, S.N.1    Habermacher, R.2    Martine, U.3    Closs, E.I.4    Filipowicz, W.5
  • 222
    • 77956278708 scopus 로고    scopus 로고
    • Deep sequencing of human nuclear and cytoplasmic small RNAs reveals an unexpectedly complex subcellular distribution of miRNAs and tRNA 3' trailers
    • Liao, J. Y.; Ma, L. M.; Guo, Y. H.; Zhang, Y. C.; Zhou, H.; Shao, P.; Chen, Y. Q.; Qu, L. H. Deep sequencing of human nuclear and cytoplasmic small RNAs reveals an unexpectedly complex subcellular distribution of miRNAs and tRNA 3' trailers. PLoS One, 2010, 5, e10563.
    • (2010) PLoS One , vol.5
    • Liao, J.Y.1    Ma, L.M.2    Guo, Y.H.3    Zhang, Y.C.4    Zhou, H.5    Shao, P.6    Chen, Y.Q.7    Qu, L.H.8
  • 223
    • 40349090024 scopus 로고    scopus 로고
    • MiRNA and piRNA localization in the male mammalian meiotic nucleus
    • Marcon, E.; Babak, T.; Chua, G.; Hughes, T.; Moens, P. B. MiRNA and piRNA localization in the male mammalian meiotic nucleus. Chromosome Res., 2008, 16, 243-260
    • (2008) Chromosome Res , vol.16 , pp. 243-260
    • Marcon, E.1    Babak, T.2    Chua, G.3    Hughes, T.4    Moens, P.B.5
  • 224
    • 35548971658 scopus 로고    scopus 로고
    • MicroRNA-206 colocalizes with ribosome-rich regions in both the nucleolus and cytoplasm of rat myogenic cells
    • Politz, J. C.; Zhang, F.; Pederson, T. MicroRNA-206 colocalizes with ribosome-rich regions in both the nucleolus and cytoplasm of rat myogenic cells. Proc. Natl. Acad. Sci. USA, 2006, 103, 18957-18962.
    • (2006) Proc. Natl. Acad. Sci. USA , vol.103 , pp. 18957-18962
    • Politz, J.C.1    Zhang, F.2    Pederson, T.3
  • 227
    • 48249088866 scopus 로고    scopus 로고
    • Molecular biology. RNA interference in the nucleus
    • Meister, G. Molecular biology. RNA interference in the nucleus. Science, 2008, 321, 496-497.
    • (2008) Science , vol.321 , pp. 496-497
    • Meister, G.1
  • 230
  • 232
    • 0034614637 scopus 로고    scopus 로고
    • The hallmarks of cancer
    • Hanahan, D.; Weinberg, R. A. The hallmarks of cancer. Cell, 2000, 100, 57-70.
    • (2000) Cell , vol.100 , pp. 57-70
    • Hanahan, D.1    Weinberg, R.A.2
  • 233
    • 38749114995 scopus 로고    scopus 로고
    • Oncogenes and cancer
    • Croce, C. M. Oncogenes and cancer. N. Engl. J. Med., 2008, 358, 502-511.
    • (2008) N. Engl. J. Med , vol.358 , pp. 502-511
    • Croce, C.M.1
  • 234
    • 0004334206 scopus 로고
    • Cell lines and clinical isolates derived from Ph1- positive chronic myelogenous leukemia patients express c-abl proteins with a common structural alteration
    • Konopka, J. B.; Watanabe, S. M.; Singer, J. W.; Collins, S. J.; Witte, O. N. Cell lines and clinical isolates derived from Ph1- positive chronic myelogenous leukemia patients express c-abl proteins with a common structural alteration. Proc. Natl. Acad. Sci. USA, 1985, 82, 1810-1814.
    • (1985) Proc. Natl. Acad. Sci. USA , vol.82 , pp. 1810-1814
    • Konopka, J.B.1    Watanabe, S.M.2    Singer, J.W.3    Collins, S.J.4    Witte, O.N.5
  • 235
    • 0021829149 scopus 로고
    • Clustering of breakpoints on chromosome 11 in human B-cell neoplasms with the t(11;14) chromosome translocation
    • Tsujimoto, Y.; Jaffe, E.; Cossman, J.; Gorham, J.; Nowell, P. C.; Croce, C. M. Clustering of breakpoints on chromosome 11 in human B-cell neoplasms with the t(11;14) chromosome translocation. Nature, 1985, 315, 340-343.
    • (1985) Nature , vol.315 , pp. 340-343
    • Tsujimoto, Y.1    Jaffe, E.2    Cossman, J.3    Gorham, J.4    Nowell, P.C.5    Croce, C.M.6
  • 236
    • 0842346437 scopus 로고    scopus 로고
    • Principles of tumor suppression
    • Sherr, C. J. Principles of tumor suppression. Cell, 2004, 116, 235-246.
    • (2004) Cell , vol.116 , pp. 235-246
    • Sherr, C.J.1
  • 237
    • 33846846397 scopus 로고    scopus 로고
    • MicroRNA and cancer: Current status and prospective
    • Wu, W.; Sun, M.; Zou, G. M.; Chen, J. MicroRNA and cancer: Current status and prospective. Int. J. Cancer, 2007, 120, 953-960.
    • (2007) Int. J. Cancer , vol.120 , pp. 953-960
    • Wu, W.1    Sun, M.2    Zou, G.M.3    Chen, J.4
  • 238
    • 33749504736 scopus 로고    scopus 로고
    • MicroRNAs and the hallmarks of cancer
    • Dalmay, T.; Edwards, D. R. MicroRNAs and the hallmarks of cancer. Oncogene, 2006, 25, 6170-6175.
    • (2006) Oncogene , vol.25 , pp. 6170-6175
    • Dalmay, T.1    Edwards, D.R.2
  • 239
    • 33645294070 scopus 로고    scopus 로고
    • Oncomirs - microRNAs with a role in cancer
    • Esquela-Kerscher, A.; Slack, F. J. Oncomirs - microRNAs with a role in cancer. Nat. Rev. Cancer, 2006, 6, 259-269.
    • (2006) Nat. Rev. Cancer , vol.6 , pp. 259-269
    • Esquela-Kerscher, A.1    Slack, F.J.2
  • 240
    • 33645321647 scopus 로고    scopus 로고
    • MicroRNAs in cell proliferation, cell death, and tumorigenesis
    • Hwang, H. W.; Mendell, J. T. MicroRNAs in cell proliferation, cell death, and tumorigenesis. Br. J. Cancer, 2006, 94, 776-780.
    • (2006) Br. J. Cancer , vol.94 , pp. 776-780
    • Hwang, H.W.1    Mendell, J.T.2
  • 246
    • 0033594123 scopus 로고    scopus 로고
    • Rho GTPases control polarity, protrusion, and adhesion during cell movement
    • Nobes, C. D.; Hall, A. Rho GTPases control polarity, protrusion, and adhesion during cell movement. J. Cell Biol., 1999, 144, 1235-1244.
    • (1999) J. Cell Biol , vol.144 , pp. 1235-1244
    • Nobes, C.D.1    Hall, A.2
  • 247
    • 0035934224 scopus 로고    scopus 로고
    • Activation of mitogen-activated protein kinase cascade and phosphorylation of cytoskeletal proteins after neurone-specific activation of p21ras. II. Cytoskeletal proteins and dendritic morphology
    • Holzer, M.; Rodel, L.; Seeger, G.; Gartner, U.; Narz, F.; Janke, C.; Heumann, R.; Arendt, T. Activation of mitogen-activated protein kinase cascade and phosphorylation of cytoskeletal proteins after neurone-specific activation of p21ras. II. Cytoskeletal proteins and dendritic morphology. Neuroscience, 2001, 105, 1041-1054.
    • (2001) Neuroscience , vol.105 , pp. 1041-1054
    • Holzer, M.1    Rodel, L.2    Seeger, G.3    Gartner, U.4    Narz, F.5    Janke, C.6    Heumann, R.7    Arendt, T.8
  • 248
    • 0035936807 scopus 로고    scopus 로고
    • Hyperproliferation and defects in epithelial polarity upon conditional ablation of alpha-catenin in skin
    • Vasioukhin, V.; Bauer, C.; Degenstein, L.; Wise, B.; Fuchs, E. Hyperproliferation and defects in epithelial polarity upon conditional ablation of alpha-catenin in skin. Cell, 2001, 104, 605-617.
    • (2001) Cell , vol.104 , pp. 605-617
    • Vasioukhin, V.1    Bauer, C.2    Degenstein, L.3    Wise, B.4    Fuchs, E.5
  • 249
    • 0035844149 scopus 로고    scopus 로고
    • Differential activation of the Rac pathway by Ha-Ras and K-Ras
    • Walsh, A. B.; Bar-Sagi, D. Differential activation of the Rac pathway by Ha-Ras and K-Ras. J. Biol. Chem., 2001, 276, 15609-15615.
    • (2001) J. Biol. Chem , vol.276 , pp. 15609-15615
    • Walsh, A.B.1    Bar-Sagi, D.2
  • 250
    • 0024376173 scopus 로고
    • ras oncogenes in human cancer: A review
    • Bos, J. L. ras oncogenes in human cancer: a review. Cancer Res. 1989, 49, 4682-4689.
    • (1989) Cancer Res , vol.49 , pp. 4682-4689
    • Bos, J.L.1
  • 252
    • 34248638447 scopus 로고    scopus 로고
    • Evolutionary conservation of microRNA regulatory circuits: An examination of microRNA gene complexity and conserved microRNA-target interactions through metazoan phylogeny
    • Lee, C. T.; Risom, T.; Strauss, W. M. Evolutionary conservation of microRNA regulatory circuits: an examination of microRNA gene complexity and conserved microRNA-target interactions through metazoan phylogeny. DNA Cell Biol., 2007, 26, 209-218.
    • (2007) DNA Cell Biol , vol.26 , pp. 209-218
    • Lee, C.T.1    Risom, T.2    Strauss, W.M.3
  • 254
    • 33646444884 scopus 로고    scopus 로고
    • Let-7 microRNA functions as a potential growth suppressor in human colon cancer cells
    • Akao, Y.; Nakagawa, Y.; Naoe, T. Let-7 microRNA functions as a potential growth suppressor in human colon cancer cells. Biol. Pharm. Bull., 2006, 29, 903-906.
    • (2006) Biol. Pharm. Bull , vol.29 , pp. 903-906
    • Akao, Y.1    Nakagawa, Y.2    Naoe, T.3
  • 255
    • 0035904395 scopus 로고    scopus 로고
    • Molecular biology of HMGA proteins: Hubs of nuclear function
    • Reeves, R. Molecular biology of HMGA proteins: hubs of nuclear function. Gene, 2001, 277, 63-81.
    • (2001) Gene , vol.277 , pp. 63-81
    • Reeves, R.1
  • 256
    • 0037677597 scopus 로고    scopus 로고
    • Etiology and pathogenesis of uterine leiomyomas: A review
    • Flake, G. P.; Andersen, J.; Dixon, D. Etiology and pathogenesis of uterine leiomyomas: a review. Environ. Health Perspect., 2003, 111, 1037-1054.
    • (2003) Environ. Health Perspect , vol.111 , pp. 1037-1054
    • Flake, G.P.1    Andersen, J.2    Dixon, D.3
  • 258
    • 0035139934 scopus 로고    scopus 로고
    • Leiomyomata: Heritability and cytogenetic studies
    • Ligon, A. H.; Morton, C. C. Leiomyomata: heritability and cytogenetic studies. Hum. Reprod. Update, 2001, 7, 8-14.
    • (2001) Hum. Reprod. Update , vol.7 , pp. 8-14
    • Ligon, A.H.1    Morton, C.C.2
  • 260
    • 34247593034 scopus 로고    scopus 로고
    • Impaired microRNA processing enhances cellular transformation and tumorigenesis
    • Kumar, M. S.; Lu, J.; Mercer, K. L.; Golub, T. R.; Jacks, T. Impaired microRNA processing enhances cellular transformation and tumorigenesis. Nat. Genet., 2007, 39, 673-677.
    • (2007) Nat. Genet , vol.39 , pp. 673-677
    • Kumar, M.S.1    Lu, J.2    Mercer, K.L.3    Golub, T.R.4    Jacks, T.5
  • 263
    • 44949249814 scopus 로고    scopus 로고
    • MiR-15b and miR-16 modulate multidrug resistance by targeting BCL2 in human gastric cancer cells
    • Xia, L.; Zhang, D.; Du, R.; Pan, Y.; Zhao, L.; Sun, S.; Hong, L.; Liu, J.; Fan, D. MiR-15b and miR-16 modulate multidrug resistance by targeting BCL2 in human gastric cancer cells. Int. J. Cancer, 2008, 123, 372-379.
    • (2008) Int. J. Cancer , vol.123 , pp. 372-379
    • Xia, L.1    Zhang, D.2    Du, R.3    Pan, Y.4    Zhao, L.5    Sun, S.6    Hong, L.7    Liu, J.8    Fan, D.9
  • 264
    • 0036716281 scopus 로고    scopus 로고
    • The Bcl2 family: Regulators of the cellular life-or-death switch
    • Cory, S.; Adams, J. M. The Bcl2 family: regulators of the cellular life-or-death switch. Nat. Rev. Cancer, 2002, 2, 647-656.
    • (2002) Nat. Rev. Cancer , vol.2 , pp. 647-656
    • Cory, S.1    Adams, J.M.2
  • 265
    • 0037441895 scopus 로고    scopus 로고
    • Cell cycle deregulation in B-cell lymphomas
    • Sanchez-Beato, M.; Sanchez-Aguilera, A.; Piris, M. A. Cell cycle deregulation in B-cell lymphomas. Blood, 2003, 101, 1220-1235.
    • (2003) Blood , vol.101 , pp. 1220-1235
    • Sanchez-Beato, M.1    Sanchez-Aguilera, A.2    Piris, M.A.3
  • 268
    • 3943071150 scopus 로고    scopus 로고
    • Cytochrome C-mediated apoptosis
    • Jiang, X.; Wang, X. Cytochrome C-mediated apoptosis. Annu. Rev. Biochem., 2004, 73, 87-106.
    • (2004) Annu. Rev. Biochem , vol.73 , pp. 87-106
    • Jiang, X.1    Wang, X.2
  • 269
    • 0142117313 scopus 로고    scopus 로고
    • The Bcl-2 family: Roles in cell survival and oncogenesis
    • Cory, S.; Huang, D. C.; Adams, J. M. The Bcl-2 family: roles in cell survival and oncogenesis. Oncogene, 2003, 22, 8590-8607.
    • (2003) Oncogene , vol.22 , pp. 8590-8607
    • Cory, S.1    Huang, D.C.2    Adams, J.M.3
  • 270
    • 0034630167 scopus 로고    scopus 로고
    • Induction of apoptosis by cancer chemotherapy
    • Kaufmann, S. H.; Earnshaw, W. C. Induction of apoptosis by cancer chemotherapy. Exp. Cell Res., 2000, 256, 42-49.
    • (2000) Exp. Cell Res , vol.256 , pp. 42-49
    • Kaufmann, S.H.1    Earnshaw, W.C.2
  • 271
    • 0033773114 scopus 로고    scopus 로고
    • Apoptosis in cancer: Cause and cure
    • Kaufmann, S. H.; Gores, G. J. Apoptosis in cancer: cause and cure. Bioessays, 2000, 22, 1007-1017.
    • (2000) Bioessays , vol.22 , pp. 1007-1017
    • Kaufmann, S.H.1    Gores, G.J.2
  • 272
    • 34247336873 scopus 로고    scopus 로고
    • Bcl2/bcl-xL inhibitor engenders apoptosis and increases chemosensitivity in mesothelioma
    • Cao, X.; Rodarte, C.; Zhang, L.; Morgan, C. D.; Littlejohn, J.; Smythe, W. R. Bcl2/bcl-xL inhibitor engenders apoptosis and increases chemosensitivity in mesothelioma. Cancer Biol. Ther., 2007, 6, 246-252.
    • (2007) Cancer Biol. Ther , vol.6 , pp. 246-252
    • Cao, X.1    Rodarte, C.2    Zhang, L.3    Morgan, C.D.4    Littlejohn, J.5    Smythe, W.R.6
  • 274
    • 22244467087 scopus 로고    scopus 로고
    • MicroRNA-21 is an antiapoptotic factor in human glioblastoma cells
    • Chan, J. A.; Krichevsky, A. M.; Kosik, K. S. MicroRNA-21 is an antiapoptotic factor in human glioblastoma cells. Cancer Res., 2005, 65, 6029-6033.
    • (2005) Cancer Res , vol.65 , pp. 6029-6033
    • Chan, J.A.1    Krichevsky, A.M.2    Kosik, K.S.3
  • 275
    • 34547524771 scopus 로고    scopus 로고
    • MicroRNA-21 regulates expression of the PTEN tumor suppressor gene in human hepatocellular cancer
    • Meng, F.; Henson, R.; Wehbe-Janek, H.; Ghoshal, K.; Jacob, S. T.; Patel, T. MicroRNA-21 regulates expression of the PTEN tumor suppressor gene in human hepatocellular cancer. Gastroenterology, 2007, 133, 647-658.
    • (2007) Gastroenterology , vol.133 , pp. 647-658
    • Meng, F.1    Henson, R.2    Wehbe-Janek, H.3    Ghoshal, K.4    Jacob, S.T.5    Patel, T.6
  • 276
    • 57049090610 scopus 로고    scopus 로고
    • MicroRNA-21 is overexpressed in pancreatic cancer and a potential predictor of survival
    • Dillhoff, M.; Liu, J.; Frankel, W.; Croce, C.; Bloomston, M. MicroRNA-21 is overexpressed in pancreatic cancer and a potential predictor of survival. J. Gastrointest. Surg., 2008, 12(12), 2171-6.
    • (2008) J. Gastrointest. Surg , vol.12 , Issue.12 , pp. 2171-2176
    • Dillhoff, M.1    Liu, J.2    Frankel, W.3    Croce, C.4    Bloomston, M.5
  • 277
    • 41749113108 scopus 로고    scopus 로고
    • MicroRNA-21 (miR-21) post-transcriptionally downregulates tumor suppressor Pdcd4 and stimulates invasion, intravasation and metastasis in colorectal cancer
    • Asangani, I. A.; Rasheed, S. A.; Nikolova, D. A.; Leupold, J. H.; Colburn, N. H.; Post, S.; Allgayer, H. MicroRNA-21 (miR-21) post-transcriptionally downregulates tumor suppressor Pdcd4 and stimulates invasion, intravasation and metastasis in colorectal cancer. Oncogene, 2008, 27, 2128-2136.
    • (2008) Oncogene , vol.27 , pp. 2128-2136
    • Asangani, I.A.1    Rasheed, S.A.2    Nikolova, D.A.3    Leupold, J.H.4    Colburn, N.H.5    Post, S.6    Allgayer, H.7
  • 279
    • 33750600178 scopus 로고    scopus 로고
    • MicroRNA expression abnormalities in pancreatic endocrine and acinar tumors are associated with distinctive pathologic features and clinical behavior
    • Roldo, C.; Missiaglia, E.; Hagan, J. P.; Falconi, M.; Capelli, P.; Bersani, S.; Calin, G. A.; Volinia, S.; Liu, C. G.; Scarpa, A.; Croce, C. M. MicroRNA expression abnormalities in pancreatic endocrine and acinar tumors are associated with distinctive pathologic features and clinical behavior. J. Clin. Oncol., 2006, 24, 4677-4684.
    • (2006) J. Clin. Oncol , vol.24 , pp. 4677-4684
    • Roldo, C.1    Missiaglia, E.2    Hagan, J.P.3    Falconi, M.4    Capelli, P.5    Bersani, S.6    Calin, G.A.7    Volinia, S.8    Liu, C.G.9    Scarpa, A.10    Croce, C.M.11
  • 280
    • 40249092910 scopus 로고    scopus 로고
    • MicroRNA-21 targets tumor suppressor genes in invasion and metastasis
    • Zhu, S.; Wu, H.; Wu, F.; Nie, D.; Sheng, S.; Mo, Y. Y. MicroRNA-21 targets tumor suppressor genes in invasion and metastasis. Cell Res., 2008, 18, 350-359.
    • (2008) Cell Res , vol.18 , pp. 350-359
    • Zhu, S.1    Wu, H.2    Wu, F.3    Nie, D.4    Sheng, S.5    Mo, Y.Y.6
  • 281
    • 47549109566 scopus 로고    scopus 로고
    • MicroRNA-21 promotes cell transformation by targeting the programmed cell death 4 gene
    • Lu, Z.; Liu, M.; Stribinskis, V.; Klinge, C. M.; Ramos, K. S.; Colburn, N. H.; Li, Y. MicroRNA-21 promotes cell transformation by targeting the programmed cell death 4 gene. Oncogene, 2008, 27, 4373-4379.
    • (2008) Oncogene , vol.27 , pp. 4373-4379
    • Lu, Z.1    Liu, M.2    Stribinskis, V.3    Klinge, C.M.4    Ramos, K.S.5    Colburn, N.H.6    Li, Y.7
  • 282
    • 34347266556 scopus 로고    scopus 로고
    • MicroRNA-21 targets the tumor suppressor gene tropomyosin 1 (TPM1)
    • Zhu, S.; Si, M. L.; Wu, H.; Mo, Y. Y. MicroRNA-21 targets the tumor suppressor gene tropomyosin 1 (TPM1). J. Biol. Chem., 2007, 282(19), 14328-36.
    • (2007) J. Biol. Chem , vol.282 , Issue.19 , pp. 14328-14336
    • Zhu, S.1    Si, M.L.2    Wu, H.3    Mo, Y.Y.4
  • 283
    • 33644834046 scopus 로고    scopus 로고
    • Tumours and tremors: How PTEN regulation underlies both
    • Kim, R. H.; Mak, T. W. Tumours and tremors: how PTEN regulation underlies both. Br. J. Cancer, 2006, 94, 620-624.
    • (2006) Br. J. Cancer , vol.94 , pp. 620-624
    • Kim, R.H.1    Mak, T.W.2
  • 284
    • 0037205230 scopus 로고    scopus 로고
    • Tumor suppressor PTEN mediates sensing of chemoattractant gradients
    • Iijima, M.; Devreotes, P. Tumor suppressor PTEN mediates sensing of chemoattractant gradients. Cell, 2002, 109, 599-610.
    • (2002) Cell , vol.109 , pp. 599-610
    • Iijima, M.1    Devreotes, P.2
  • 285
    • 4344602002 scopus 로고    scopus 로고
    • The biology and clinical relevance of the PTEN tumor suppressor pathway
    • Sansal, I.; Sellers, W. R. The biology and clinical relevance of the PTEN tumor suppressor pathway. J. Clin. Oncol., 2004, 22, 2954-2963.
    • (2004) J. Clin. Oncol , vol.22 , pp. 2954-2963
    • Sansal, I.1    Sellers, W.R.2
  • 286
    • 0036830240 scopus 로고    scopus 로고
    • PTEN suppresses hyaluronic acid-induced matrix metalloproteinase-9 expression in U87MG glioblastoma cells through focal adhesion kinase dephosphorylation
    • Park, M. J.; Kim, M. S.; Park, I. C.; Kang, H. S.; Yoo, H.; Park, S. H.; Rhee, C. H.; Hong, S. I.; Lee, S. H. PTEN suppresses hyaluronic acid-induced matrix metalloproteinase-9 expression in U87MG glioblastoma cells through focal adhesion kinase dephosphorylation. Cancer Res., 2002, 62, 6318-6322.
    • (2002) Cancer Res , vol.62 , pp. 6318-6322
    • Park, M.J.1    Kim, M.S.2    Park, I.C.3    Kang, H.S.4    Yoo, H.5    Park, S.H.6    Rhee, C.H.7    Hong, S.I.8    Lee, S.H.9
  • 287
    • 0034841005 scopus 로고    scopus 로고
    • Vertebrate tropomyosin: Distribution, properties and function
    • Perry, S. V. Vertebrate tropomyosin: distribution, properties and function. J. Muscle Res. Cell Motil., 2001, 22, 5-49.
    • (2001) J. Muscle Res. Cell Motil , vol.22 , pp. 5-49
    • Perry, S.V.1
  • 289
    • 38149042783 scopus 로고    scopus 로고
    • Programmed cell death 4 (PDCD4) is an important functional target of the microRNA miR-21 in breast cancer cells
    • Frankel, L. B.; Christoffersen, N. R.; Jacobsen, A.; Lindow, M.; Krogh, A.; Lund, A. H. Programmed cell death 4 (PDCD4) is an important functional target of the microRNA miR-21 in breast cancer cells. J. Biol. Chem., 2008, 283, 1026-1033.
    • (2008) J. Biol. Chem , vol.283 , pp. 1026-1033
    • Frankel, L.B.1    Christoffersen, N.R.2    Jacobsen, A.3    Lindow, M.4    Krogh, A.5    Lund, A.H.6
  • 290
    • 33646271356 scopus 로고    scopus 로고
    • Maspin retards cell detachment via a novel interaction with the urokinase-type plasminogen activator/urokinase-type plasminogen activator receptor system
    • Yin, S.; Lockett, J.; Meng, Y.; Biliran, H., Jr.; Blouse, G. E.; Li, X.; Reddy, N.; Zhao, Z.; Lin, X.; Anagli, J.; Cher, M. L.; Sheng, S. Maspin retards cell detachment via a novel interaction with the urokinase-type plasminogen activator/urokinase-type plasminogen activator receptor system. Cancer Res., 2006, 66, 4173-4181.
    • (2006) Cancer Res , vol.66 , pp. 4173-4181
    • Yin, S.1    Lockett, J.2    Meng, Y.3    Biliran Jr., H.4    Blouse, G.E.5    Li, X.6    Reddy, N.7    Zhao, Z.8    Lin, X.9    Anagli, J.10    Cher, M.L.11    Sheng, S.12
  • 291
    • 34447270490 scopus 로고    scopus 로고
    • Tumor suppressor Pdcd4 inhibits invasion/ intravasation and regulates urokinase receptor (u-PAR) gene expression via Sp-transcription factors
    • Leupold, J. H.; Yang, H. S.; Colburn, N. H.; Asangani, I.; Post, S.; Allgayer, H. Tumor suppressor Pdcd4 inhibits invasion/ intravasation and regulates urokinase receptor (u-PAR) gene expression via Sp-transcription factors. Oncogene, 2007, 26, 4550-4562.
    • (2007) Oncogene , vol.26 , pp. 4550-4562
    • Leupold, J.H.1    Yang, H.S.2    Colburn, N.H.3    Asangani, I.4    Post, S.5    Allgayer, H.6
  • 293
    • 41949102707 scopus 로고    scopus 로고
    • MiRiad roles for the miR-17-92 cluster in development and disease
    • Mendell, J. T. MiRiad roles for the miR-17-92 cluster in development and disease. Cell, 2008, 133, 217-222.
    • (2008) Cell , vol.133 , pp. 217-222
    • Mendell, J.T.1
  • 294
    • 2342449399 scopus 로고    scopus 로고
    • Identification and characterization of a novel gene, C13orf25, as a target for 13q31-q32 amplification in malignant lymphoma
    • Ota, A.; Tagawa, H.; Karnan, S.; Tsuzuki, S.; Karpas, A.; Kira, S.; Yoshida, Y.; Seto, M. Identification and characterization of a novel gene, C13orf25, as a target for 13q31-q32 amplification in malignant lymphoma. Cancer Res., 2004, 64, 3087-3095.
    • (2004) Cancer Res , vol.64 , pp. 3087-3095
    • Ota, A.1    Tagawa, H.2    Karnan, S.3    Tsuzuki, S.4    Karpas, A.5    Kira, S.6    Yoshida, Y.7    Seto, M.8
  • 301
    • 0033551390 scopus 로고    scopus 로고
    • The Myc oncoprotein: A critical evaluation of transactivation and target gene regulation
    • Cole, M. D.; McMahon, S. B. The Myc oncoprotein: a critical evaluation of transactivation and target gene regulation. Oncogene, 1999, 18, 2916-2924.
    • (1999) Oncogene , vol.18 , pp. 2916-2924
    • Cole, M.D.1    McMahon, S.B.2
  • 302
    • 0035882058 scopus 로고    scopus 로고
    • Deconstructing myc
    • Eisenman, R. N. Deconstructing myc. Genes Dev., 2001, 15, 2023-2030.
    • (2001) Genes Dev , vol.15 , pp. 2023-2030
    • Eisenman, R.N.1
  • 306
    • 0027491775 scopus 로고
    • Expression of transcription factor E2F1 induces quiescent cells to enter S phase
    • Johnson, D. G.; Schwarz, J. K.; Cress, W. D.; Nevins, J. R. Expression of transcription factor E2F1 induces quiescent cells to enter S phase. Nature, 1993, 365, 349-352.
    • (1993) Nature , vol.365 , pp. 349-352
    • Johnson, D.G.1    Schwarz, J.K.2    Cress, W.D.3    Nevins, J.R.4
  • 309
    • 10644270921 scopus 로고    scopus 로고
    • P73 induction after DNA damage is regulated by checkpoint kinases Chk1 and Chk2
    • Urist, M.; Tanaka, T.; Poyurovsky, M. V.; Prives, C. P73 induction after DNA damage is regulated by checkpoint kinases Chk1 and Chk2. Genes Dev., 2004, 18, 3041-3054.
    • (2004) Genes Dev , vol.18 , pp. 3041-3054
    • Urist, M.1    Tanaka, T.2    Poyurovsky, M.V.3    Prives, C.4
  • 310
    • 0035878122 scopus 로고    scopus 로고
    • Selective induction of E2F1 in response to DNA damage, mediated by ATM-dependent phosphorylation
    • Lin, W. C.; Lin, F. T.; Nevins, J. R. Selective induction of E2F1 in response to DNA damage, mediated by ATM-dependent phosphorylation. Genes Dev., 2001, 15, 1833-1844.
    • (2001) Genes Dev , vol.15 , pp. 1833-1844
    • Lin, W.C.1    Lin, F.T.2    Nevins, J.R.3
  • 311
    • 0028960617 scopus 로고
    • E2F1 overexpression in quiescent fibroblasts leads to induction of cellular DNA synthesis and apoptosis
    • Kowalik, T. F.; DeGregori, J.; Schwarz, J. K.; Nevins, J. R. E2F1 overexpression in quiescent fibroblasts leads to induction of cellular DNA synthesis and apoptosis. J. Virol., 1995, 69, 2491-2500.
    • (1995) J. Virol , vol.69 , pp. 2491-2500
    • Kowalik, T.F.1    Degregori, J.2    Schwarz, J.K.3    Nevins, J.R.4
  • 312
    • 0037010122 scopus 로고    scopus 로고
    • E2F1 pathways to apoptosis
    • Ginsberg, D. E2F1 pathways to apoptosis. FEBS Lett., 2002, 529, 122-125.
    • (2002) FEBS Lett , vol.529 , pp. 122-125
    • Ginsberg, D.1
  • 313
    • 34548381748 scopus 로고    scopus 로고
    • Myc'ed messages: Myc induces transcription of E2F1 while inhibiting its translation via a microRNA polycistron
    • Coller, H. A.; Forman, J. J.; Legesse-Miller, A. Myc'ed messages: myc induces transcription of E2F1 while inhibiting its translation via a microRNA polycistron. PLoS Genet., 2007, 3, e146.
    • (2007) PLoS Genet , vol.3
    • Coller, H.A.1    Forman, J.J.2    Legesse-Miller, A.3
  • 315
    • 0024651359 scopus 로고
    • Nuclear factor E2F mediates basic transcription and transactivation by E1a of the human MYC promoter
    • Thalmeier, K.; Synovzik, H.; Mertz, R.; Winnacker, E. L.; Lipp, M. Nuclear factor E2F mediates basic transcription and transactivation by E1a of the human MYC promoter. Genes Dev., 1989, 3, 527-536.
    • (1989) Genes Dev , vol.3 , pp. 527-536
    • Thalmeier, K.1    Synovzik, H.2    Mertz, R.3    Winnacker, E.L.4    Lipp, M.5
  • 316
    • 0142027814 scopus 로고    scopus 로고
    • Structure and function of the feed-forward loop network motif
    • Mangan, S.; Alon, U. Structure and function of the feed-forward loop network motif. Proc. Natl. Acad. Sci. USA, 2003, 100, 11980-11985.
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 11980-11985
    • Mangan, S.1    Alon, U.2
  • 317
    • 22044445947 scopus 로고    scopus 로고
    • Molecular studies of loss of heterozygosity in Chinese sporadic retinoblastoma patients
    • Zhang, X. L.; Fu, W. L.; Zhao, H. X.; Zhou, L. X.; Huang, J. F.; Wang, J. H. Molecular studies of loss of heterozygosity in Chinese sporadic retinoblastoma patients. Clin. Chim. Acta, 2005, 358, 75-80.
    • (2005) Clin. Chim. Acta , vol.358 , pp. 75-80
    • Zhang, X.L.1    Fu, W.L.2    Zhao, H.X.3    Zhou, L.X.4    Huang, J.F.5    Wang, J.H.6
  • 318
    • 0033369354 scopus 로고    scopus 로고
    • Loss of heterozygosity at chromosome 13q in hepatocellular carcinoma: Identification of three independent regions
    • Lin, Y. W.; Sheu, J. C.; Liu, L. Y.; Chen, C. H.; Lee, H. S.; Huang, G. T.; Wang, J. T.; Lee, P. H.; Lu, F. J. Loss of heterozygosity at chromosome 13q in hepatocellular carcinoma: identification of three independent regions. Eur. J. Cancer, 1999, 35, 1730-1734.
    • (1999) Eur. J. Cancer , vol.35 , pp. 1730-1734
    • Lin, Y.W.1    Sheu, J.C.2    Liu, L.Y.3    Chen, C.H.4    Lee, H.S.5    Huang, G.T.6    Wang, J.T.7    Lee, P.H.8    Lu, F.J.9
  • 320
    • 0036107699 scopus 로고    scopus 로고
    • High frequency loss of heterozygosity on the long arms of chromosomes 13 and 14 in nasopharyngeal carcinoma in Southern China
    • Shao, J.; Li, Y.; Wu, Q.; Liang, X.; Yu, X.; Huang, L.; Hou, J.; Huang, X.; Ernberg, I.; Hu, L. F.; Zeng, Y. High frequency loss of heterozygosity on the long arms of chromosomes 13 and 14 in nasopharyngeal carcinoma in Southern China. Chin. Med. J. (Engl), 2002, 115, 571-575.
    • (2002) Chin. Med. J. (Engl) , vol.115 , pp. 571-575
    • Shao, J.1    Li, Y.2    Wu, Q.3    Liang, X.4    Yu, X.5    Huang, L.6    Hou, J.7    Huang, X.8    Ernberg, I.9    Hu, L.F.10    Zeng, Y.11
  • 321
    • 33750376591 scopus 로고    scopus 로고
    • Mir-17-5p regulates breast cancer cell proliferation by inhibiting translation of AIB1 mRNA
    • Hossain, A.; Kuo, M. T.; Saunders, G. F. Mir-17-5p regulates breast cancer cell proliferation by inhibiting translation of AIB1 mRNA. Mol. Cell. Biol., 2006, 26, 8191-8201.
    • (2006) Mol. Cell. Biol , vol.26 , pp. 8191-8201
    • Hossain, A.1    Kuo, M.T.2    Saunders, G.F.3
  • 322
    • 33645237486 scopus 로고    scopus 로고
    • SRC-3/AIB1: Transcriptional coactivator in oncogenesis
    • Yan, J.; Tsai, S. Y.; Tsai, M. J. SRC-3/AIB1: transcriptional coactivator in oncogenesis. Acta Pharmacol. Sin., 2006, 27, 387-394.
    • (2006) Acta Pharmacol. Sin , vol.27 , pp. 387-394
    • Yan, J.1    Tsai, S.Y.2    Tsai, M.J.3
  • 324
    • 2942628182 scopus 로고    scopus 로고
    • ACTR/AIB1 functions as an E2F1 coactivator to promote breast cancer cell proliferation and antiestrogen resistance
    • Louie, M. C.; Zou, J. X.; Rabinovich, A.; Chen, H. W. ACTR/AIB1 functions as an E2F1 coactivator to promote breast cancer cell proliferation and antiestrogen resistance. Mol. Cell. Biol., 2004, 24, 5157-5171.
    • (2004) Mol. Cell. Biol , vol.24 , pp. 5157-5171
    • Louie, M.C.1    Zou, J.X.2    Rabinovich, A.3    Chen, H.W.4
  • 325
    • 8544284122 scopus 로고    scopus 로고
    • The nuclear receptor coactivator AIB1 mediates insulin-like growth factor I-induced phenotypic changes in human breast cancer cells
    • Oh, A.; List, H. J.; Reiter, R.; Mani, A.; Zhang, Y.; Gehan, E.; Wellstein, A.; Riegel, A. T. The nuclear receptor coactivator AIB1 mediates insulin-like growth factor I-induced phenotypic changes in human breast cancer cells. Cancer Res., 2004, 64, 8299-8308.
    • (2004) Cancer Res , vol.64 , pp. 8299-8308
    • Oh, A.1    List, H.J.2    Reiter, R.3    Mani, A.4    Zhang, Y.5    Gehan, E.6    Wellstein, A.7    Riegel, A.T.8
  • 327
    • 0142059907 scopus 로고    scopus 로고
    • Role of the steroid receptor coactivator SRC-3 in cell growth
    • Zhou, G.; Hashimoto, Y.; Kwak, I.; Tsai, S. Y.; Tsai, M. J. Role of the steroid receptor coactivator SRC-3 in cell growth. Mol. Cell Biol., 2003, 23, 7742-7755.
    • (2003) Mol. Cell Biol , vol.23 , pp. 7742-7755
    • Zhou, G.1    Hashimoto, Y.2    Kwak, I.3    Tsai, S.Y.4    Tsai, M.J.5
  • 328
    • 29444449329 scopus 로고    scopus 로고
    • Steroid receptor coactivator (SRC)-1 and SRC-3 differentially modulate tissue-specific activation functions of the progesterone receptor
    • Han, S. J.; DeMayo, F. J.; Xu, J.; Tsai, S. Y.; Tsai, M. J.; O'Malley, B. W. Steroid receptor coactivator (SRC)-1 and SRC-3 differentially modulate tissue-specific activation functions of the progesterone receptor. Mol. Endocrinol., 2006, 20, 45-55.
    • (2006) Mol. Endocrinol , vol.20 , pp. 45-55
    • Han, S.J.1    Demayo, F.J.2    Xu, J.3    Tsai, S.Y.4    Tsai, M.J.5    O'Malley, B.W.6
  • 331
    • 7044285911 scopus 로고    scopus 로고
    • Probing microRNAs with microarrays: Tissue specificity and functional inference
    • Babak, T.; Zhang, W.; Morris, Q.; Blencowe, B. J.; Hughes, T. R. Probing microRNAs with microarrays: tissue specificity and functional inference. RNA, 2004, 10, 1813-1819.
    • (2004) RNA , vol.10 , pp. 1813-1819
    • Babak, T.1    Zhang, W.2    Morris, Q.3    Blencowe, B.J.4    Hughes, T.R.5
  • 334
    • 16344383409 scopus 로고    scopus 로고
    • Development of a micro-array to detect human and mouse microRNAs and characterization of expression in human organs
    • Sun, Y.; Koo, S.; White, N.; Peralta, E.; Esau, C.; Dean, N. M.; Perera, R. J. Development of a micro-array to detect human and mouse microRNAs and characterization of expression in human organs. Nucleic Acids Res., 2004, 32, e188.
    • (2004) Nucleic Acids Res , vol.32
    • Sun, Y.1    Koo, S.2    White, N.3    Peralta, E.4    Esau, C.5    Dean, N.M.6    Perera, R.J.7
  • 336
    • 50249103246 scopus 로고    scopus 로고
    • MicroRNA analysis as a potential diagnostic tool for papillary thyroid carcinoma
    • Chen, Y. T.; Kitabayashi, N.; Zhou, X. K.; Fahey, T. J., 3rd.; Scognamiglio, T. MicroRNA analysis as a potential diagnostic tool for papillary thyroid carcinoma. Mod. Pathol., 2008, 21, 1139-1146.
    • (2008) Mod. Pathol , vol.21 , pp. 1139-1146
    • Chen, Y.T.1    Kitabayashi, N.2    Zhou, X.K.3    Fahey 3rd, T.J.4    Scognamiglio, T.5
  • 337
    • 33748624597 scopus 로고    scopus 로고
    • Optimized high-throughput microRNA expression profiling provides novel biomarker assessment of clinical prostate and breast cancer biopsies
    • Mattie, M. D.; Benz, C. C.; Bowers, J.; Sensinger, K.; Wong, L.; Scott, G. K.; Fedele, V.; Ginzinger, D.; Getts, R.; Haqq, C. Optimized high-throughput microRNA expression profiling provides novel biomarker assessment of clinical prostate and breast cancer biopsies. Mol. Cancer, 2006, 5, 24.
    • (2006) Mol. Cancer , vol.5 , pp. 24
    • Mattie, M.D.1    Benz, C.C.2    Bowers, J.3    Sensinger, K.4    Wong, L.5    Scott, G.K.6    Fedele, V.7    Ginzinger, D.8    Getts, R.9    Haqq, C.10
  • 338
  • 339
    • 54049115558 scopus 로고    scopus 로고
    • Prognostic value of mature microRNA- 21 and microRNA-205 overexpression in non-small cell lung cancer by quantitative real-time RT-PCR
    • Markou, A.; Tsaroucha, E. G.; Kaklamanis, L.; Fotinou, M.; Georgoulias, V.; Lianidou, E. S. Prognostic value of mature microRNA- 21 and microRNA-205 overexpression in non-small cell lung cancer by quantitative real-time RT-PCR. Clin. Chem., 2008, 54, 1696-1704.
    • (2008) Clin. Chem , vol.54 , pp. 1696-1704
    • Markou, A.1    Tsaroucha, E.G.2    Kaklamanis, L.3    Fotinou, M.4    Georgoulias, V.5    Lianidou, E.S.6
  • 343
    • 54849186900 scopus 로고    scopus 로고
    • Micro-RNAs miR125b and miR137 are frequently upregulated in response to capecitabine chemoradiotherapy of rectal cancer
    • Svoboda, M.; Izakovicova Holla, L.; Sefr, R.; Vrtkova, I.; Kocakova, I.; Tichy, B.; Dvorak, J. Micro-RNAs miR125b and miR137 are frequently upregulated in response to capecitabine chemoradiotherapy of rectal cancer. Int. J. Oncol., 2008, 33, 541-547.
    • (2008) Int. J. Oncol , vol.33 , pp. 541-547
    • Svoboda, M.1    Izakovicova, H.L.2    Sefr, R.3    Vrtkova, I.4    Kocakova, I.5    Tichy, B.6    Dvorak, J.7
  • 346
    • 35148886434 scopus 로고    scopus 로고
    • Tumour invasion and metastasis initiated by microRNA-10b in breast cancer
    • Ma, L.; Teruya-Feldstein, J.; Weinberg, R. A. Tumour invasion and metastasis initiated by microRNA-10b in breast cancer. Nature, 2007, 449, 682-688.
    • (2007) Nature , vol.449 , pp. 682-688
    • Ma, L.1    Teruya-Feldstein, J.2    Weinberg, R.A.3
  • 347
    • 77950498821 scopus 로고    scopus 로고
    • Serum microRNA signatures identified in a genome-wide serum microRNA expression profiling predict survival of non-small-cell lung cancer
    • Hu, Z.; Chen, X.; Zhao, Y.; Tian, T.; Jin, G.; Shu, Y.; Chen, Y.; Xu, L.; Zen, K.; Zhang, C.; Shen, H. Serum microRNA signatures identified in a genome-wide serum microRNA expression profiling predict survival of non-small-cell lung cancer. J. Clin. Oncol., 2010, 28, 1721-1726.
    • (2010) J. Clin. Oncol , vol.28 , pp. 1721-1726
    • Hu, Z.1    Chen, X.2    Zhao, Y.3    Tian, T.4    Jin, G.5    Shu, Y.6    Chen, Y.7    Xu, L.8    Zen, K.9    Zhang, C.10    Shen, H.11
  • 352
    • 68949181981 scopus 로고    scopus 로고
    • A robust methodology to study urine microRNA as tumor marker: MicroRNA-126 and microRNA- 182 are related to urinary bladder cancer
    • Epub ahead of print
    • Hanke, M.; Hoefig, K.; Merz, H.; Feller, A. C.; Kausch, I.; Jocham, D.; Warnecke, J. M.; Sczakiel, G. A robust methodology to study urine microRNA as tumor marker: microRNA-126 and microRNA- 182 are related to urinary bladder cancer. Urol. Oncol., 2009, [Epub ahead of print].
    • (2009) Urol. Oncol
    • Hanke, M.1    Hoefig, K.2    Merz, H.3    Feller, A.C.4    Kausch, I.5    Jocham, D.6    Warnecke, J.M.7    Sczakiel, G.8
  • 354
    • 78149409316 scopus 로고    scopus 로고
    • Export of microRNAs and microRNA-protective protein by mammalian cells
    • Epub ahead of print
    • Wang, K.; Zhang, S.; Weber, J.; Baxter, D.; Galas, D. J. Export of microRNAs and microRNA-protective protein by mammalian cells. Nucleic Acids Res., 2010, [Epub ahead of print].
    • Nucleic Acids Res , pp. 2010
    • Wang, K.1    Zhang, S.2    Weber, J.3    Baxter, D.4    Galas, D.J.5
  • 357
    • 1542328938 scopus 로고    scopus 로고
    • Characterization of amplifiable, circulating RNA in plasma and its potential as a tool for cancer diagnostics
    • El-Hefnawy, T.; Raja, S.; Kelly, L.; Bigbee, W. L.; Kirkwood, J. M.; Luketich, J. D.; Godfrey, T. E. Characterization of amplifiable, circulating RNA in plasma and its potential as a tool for cancer diagnostics. Clin. Chem., 2004, 50, 564-573.
    • (2004) Clin. Chem , vol.50 , pp. 564-573
    • El-Hefnawy, T.1    Raja, S.2    Kelly, L.3    Bigbee, W.L.4    Kirkwood, J.M.5    Luketich, J.D.6    Godfrey, T.E.7
  • 358
    • 0034865765 scopus 로고    scopus 로고
    • Is RNA in serum bound to nucleoprotein complexes?
    • Sisco, K. L. Is RNA in serum bound to nucleoprotein complexes? Clin. Chem., 2001, 47, 1744-1745.
    • (2001) Clin. Chem , vol.47 , pp. 1744-1745
    • Sisco, K.L.1
  • 359
    • 52049121293 scopus 로고    scopus 로고
    • Mature miR-184 as Potential Oncogenic microRNA of Squamous Cell Carcinoma of Tongue
    • Wong, T. S.; Liu, X. B.; Wong, B. Y.; Ng, R. W.; Yuen, A. P.; Wei, W. I. Mature miR-184 as Potential Oncogenic microRNA of Squamous Cell Carcinoma of Tongue. Clin. Cancer Res., 2008, 14, 2588-2592.
    • (2008) Clin. Cancer Res , vol.14 , pp. 2588-2592
    • Wong, T.S.1    Liu, X.B.2    Wong, B.Y.3    Ng, R.W.4    Yuen, A.P.5    Wei, W.I.6
  • 363
    • 33749236251 scopus 로고    scopus 로고
    • MicroRNA: A new player in stem cells
    • Zhang, B.; Pan, X.; Anderson, T. A. MicroRNA: a new player in stem cells. J Cell Physiol, 2006, 209, 266-269.
    • (2006) J Cell Physiol , vol.209 , pp. 266-269
    • Zhang, B.1    Pan, X.2    Anderson, T.A.3
  • 364
    • 33751250183 scopus 로고    scopus 로고
    • Computational identification of microRNAs and their targets
    • Zhang, B.; Pan, X.; Wang, Q.; Cobb, G. P.; Anderson, T. A. Computational identification of microRNAs and their targets. Comput. Biol. Chem., 2006, 30, 395-407.
    • (2006) Comput. Biol. Chem , vol.30 , pp. 395-407
    • Zhang, B.1    Pan, X.2    Wang, Q.3    Cobb, G.P.4    Anderson, T.A.5
  • 365
    • 36749094533 scopus 로고    scopus 로고
    • Discovery, biology and therapeutic potential of RNA interference, microRNA and antagomirs
    • Yang, M.; Mattes, J. Discovery, biology and therapeutic potential of RNA interference, microRNA and antagomirs. Pharmacol. Ther., 2008, 117, 94-104.
    • (2008) Pharmacol. Ther , vol.117 , pp. 94-104
    • Yang, M.1    Mattes, J.2
  • 366
    • 0036727416 scopus 로고    scopus 로고
    • Efficient delivery of siRNA for inhibition of gene expression in postnatal mice
    • Lewis, D. L.; Hagstrom, J. E.; Loomis, A. G.; Wolff, J. A.; Herweijer, H. Efficient delivery of siRNA for inhibition of gene expression in postnatal mice. Nat. Genet., 2002, 32, 107-108.
    • (2002) Nat. Genet , vol.32 , pp. 107-108
    • Lewis, D.L.1    Hagstrom, J.E.2    Loomis, A.G.3    Wolff, J.A.4    Herweijer, H.5
  • 367
    • 0042812244 scopus 로고    scopus 로고
    • A comparison of efficacy and toxicity between electroporation and adenoviral gene transfer
    • Lefesvre, P.; Attema, J.; van Bekkum, D. A comparison of efficacy and toxicity between electroporation and adenoviral gene transfer. BMC Mol. Biol., 2002, 3, 12.
    • (2002) BMC Mol. Biol , vol.3 , pp. 12
    • Lefesvre, P.1    Attema, J.2    van Bekkum, D.3
  • 368
    • 1642443401 scopus 로고    scopus 로고
    • Efficient gene transfer of HIV-1-specific short hairpin RNA into human lymphocytic cells using recombinant adeno-associated virus vectors
    • Boden, D.; Pusch, O.; Lee, F.; Tucker, L.; Ramratnam, B. Efficient gene transfer of HIV-1-specific short hairpin RNA into human lymphocytic cells using recombinant adeno-associated virus vectors. Mol. Ther., 2004, 9, 396-402.
    • (2004) Mol. Ther , vol.9 , pp. 396-402
    • Boden, D.1    Pusch, O.2    Lee, F.3    Tucker, L.4    Ramratnam, B.5
  • 371
    • 0038745599 scopus 로고    scopus 로고
    • Progress and problems with the use of viral vectors for gene therapy
    • Thomas, C. E.; Ehrhardt, A.; Kay, M. A. Progress and problems with the use of viral vectors for gene therapy. Nat. Rev. Genet., 2003, 4, 346-358.
    • (2003) Nat. Rev. Genet , vol.4 , pp. 346-358
    • Thomas, C.E.1    Ehrhardt, A.2    Kay, M.A.3
  • 372
  • 373
    • 0028937785 scopus 로고
    • Cellular and humoral immune responses to viral antigens create barriers to lung-directed gene therapy with recombinant adenoviruses
    • Yang, Y.; Li, Q.; Ertl, H. C.; Wilson, J. M. Cellular and humoral immune responses to viral antigens create barriers to lung-directed gene therapy with recombinant adenoviruses. J. Virol., 1995, 69, 2004-2015.
    • (1995) J. Virol , vol.69 , pp. 2004-2015
    • Yang, Y.1    Li, Q.2    Ertl, H.C.3    Wilson, J.M.4
  • 374
    • 22744455256 scopus 로고    scopus 로고
    • Gene therapy progress and prospects: Development of improved lentiviral and retroviral vectors--design, biosafety, and production
    • Sinn, P. L.; Sauter, S. L.; McCray, P. B., Jr. Gene therapy progress and prospects: development of improved lentiviral and retroviral vectors--design, biosafety, and production. Gene Ther., 2005, 12, 1089-1098.
    • (2005) Gene Ther , vol.12 , pp. 1089-1098
    • Sinn, P.L.1    Sauter, S.L.2    McCray Jr., P.B.3
  • 375
    • 38449089316 scopus 로고    scopus 로고
    • Predicting preferential DNA vector insertion sites: Implications for functional genomics and gene therapy
    • Hackett, C. S.; Geurts, A. M.; Hackett, P. B. Predicting preferential DNA vector insertion sites: implications for functional genomics and gene therapy. Genome Biol., 2007, 8(Suppl 1), S12.
    • (2007) Genome Biol , vol.8 , Issue.SUPPL. 1
    • Hackett, C.S.1    Geurts, A.M.2    Hackett, P.B.3
  • 376
    • 0038482054 scopus 로고    scopus 로고
    • The problem with cationic liposome/micelle-based non-viral vector systems for gene therapy
    • Miller, A. D. The problem with cationic liposome/micelle-based non-viral vector systems for gene therapy. Curr. Med. Chem., 2003, 10, 1195-1211.
    • (2003) Curr. Med. Chem , vol.10 , pp. 1195-1211
    • Miller, A.D.1


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