A TARBP2 mutation in human cancer impairs microRNA processing and DICER1 function

Nature Genetics

Volumn 41, Issue 3, 2009, Pages 365-370

  Melo, Sonia A ^a   Ropero, Santiago ^a   Moutinho, Catia ^a   Aaltonen, Lauri A ^b   Yamamoto, Hiroyuki ^c   Calin, George A ^d   Rossi, Simona ^d   Fernandez, Agustin F ^a   Carneiro, Fatima ^e   Oliveira, Carla ^e   Ferreira, Bibiana ^a   Liu, Chang Gong ^d   Villanueva, Alberto ^f   Capella, Gabriel ^f   Schwartz Jr , Simo ^g   Shiekhattar, Ramin ^h,i   Esteller, Manel ^a,i,j  

^a Centro Nacional de Investigaciones Oncológicas   (Spain)

^b UNIVERSITY OF HELSINKI   (Finland)

^c SAPPORO MEDICAL UNIVERSITY   (Japan)

^d UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^e University of Porto   (Portugal)

^f CATALAN INSTITUTE OF ONCOLOGY   (Spain)

^g HOSPITAL UNIVERSITARI VALL D HEBRON   (Spain)

^h Center for Genomic Regulation   (Spain)

ⁱ INSTITUCIÓ CATALANA DE RECERCA I ESTUDIS AVANÇATS ICREA   (Spain)

^j BELLVITGE BIOMEDICAL RESEARCH INSTITUTE IDIBELL   (Spain)

more..

Author keywords

[No Author keywords available]

Indexed keywords

BINDING PROTEIN; DOUBLE STRANDED RNA; MICRORNA; TAR RNA BINDING PROTEIN 2; UNCLASSIFIED DRUG;

ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; CARCINOMA; CELL TRANSFORMATION; CELL VIABILITY; COLON TUMOR; COLONY FORMATION; CPG ISLAND; DOWN REGULATION; ENDOMETRIUM TUMOR; FRAMESHIFT MUTATION; GENE CONTROL; GENE DISRUPTION; GENE EXPRESSION; GENE FUNCTION; GENE MUTATION; GENETIC TRANSCRIPTION; GENETIC TRANSFECTION; HISTOPATHOLOGY; HUMAN; HUMAN CELL CULTURE; HUMAN TISSUE; LOSS OF FUNCTION MUTATION; LYMPHOCYTE; METHYLATION; MICROSATELLITE INSTABILITY; NEOPLASM; ONCOGENE; POSTTRANSCRIPTIONAL GENE SILENCING; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; RNA BINDING; RNA INTERFERENCE; STOMACH TUMOR; TRANSCRIPTION REGULATION;

ANIMALS; BASE SEQUENCE; CELL LINE, TUMOR; CELL SURVIVAL; DEAD-BOX RNA HELICASES; DNA MUTATIONAL ANALYSIS; DOWN-REGULATION; HCT116 CELLS; HUMANS; MICE; MICE, NUDE; MICRORNAS; MOLECULAR SEQUENCE DATA; MUTATION; NEOPLASMS; RIBONUCLEASE III; RNA PROCESSING, POST-TRANSCRIPTIONAL; RNA-BINDING PROTEINS; TRANSFECTION;

EID: 61349127117     PISSN: 10614036     EISSN: 15461718     Source Type: Journal    
DOI: 10.1038/ng.317     Document Type: Article

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