-
1
-
-
0347444723
-
MicroRNAs: genomics, biogenesis, mechanism, and function
-
Bartel D.P. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 116 (2004) 281-297
-
(2004)
Cell
, vol.116
, pp. 281-297
-
-
Bartel, D.P.1
-
2
-
-
0344668836
-
Human let-7 stem-loop precursors harbor features of RNase III cleavage products
-
Basyuk E., Suavet F., Doglio A., Bordonne R., and Bertrand E. Human let-7 stem-loop precursors harbor features of RNase III cleavage products. Nucleic Acids Res. 31 (2003) 6593-6597
-
(2003)
Nucleic Acids Res.
, vol.31
, pp. 6593-6597
-
-
Basyuk, E.1
Suavet, F.2
Doglio, A.3
Bordonne, R.4
Bertrand, E.5
-
3
-
-
0035662491
-
Crystallographic and modeling studies of RNase III suggest a mechanism for double-stranded RNA cleavage
-
Blaszczyk J., Tropea J.E., Bubunenko M., Routzahn K.M., Waugh D.S., Court D.L., and Ji X. Crystallographic and modeling studies of RNase III suggest a mechanism for double-stranded RNA cleavage. Structure (Camb) 9 (2001) 1225-1236
-
(2001)
Structure (Camb)
, vol.9
, pp. 1225-1236
-
-
Blaszczyk, J.1
Tropea, J.E.2
Bubunenko, M.3
Routzahn, K.M.4
Waugh, D.S.5
Court, D.L.6
Ji, X.7
-
4
-
-
1642499415
-
Exportin 5 is a RanGTP-dependent dsRNA-binding protein that mediates nuclear export of pre-miRNAs
-
Bohnsack M.T., Czaplinski K., and Gorlich D. Exportin 5 is a RanGTP-dependent dsRNA-binding protein that mediates nuclear export of pre-miRNAs. RNA 10 (2004) 185-191
-
(2004)
RNA
, vol.10
, pp. 185-191
-
-
Bohnsack, M.T.1
Czaplinski, K.2
Gorlich, D.3
-
5
-
-
9344235449
-
Human microRNAs are processed from capped, polyadenylated transcripts that can also function as mRNAs
-
Cai X., Hagedorn C.H., and Cullen B.R. Human microRNAs are processed from capped, polyadenylated transcripts that can also function as mRNAs. RNA 10 (2004) 1957-1966
-
(2004)
RNA
, vol.10
, pp. 1957-1966
-
-
Cai, X.1
Hagedorn, C.H.2
Cullen, B.R.3
-
6
-
-
0346727524
-
MicroRNAs modulate hematopoietic lineage differentiation
-
Chen C.Z., Li L., Lodish H.F., and Bartel D.P. MicroRNAs modulate hematopoietic lineage differentiation. Science 303 (2004) 83-86
-
(2004)
Science
, vol.303
, pp. 83-86
-
-
Chen, C.Z.1
Li, L.2
Lodish, H.F.3
Bartel, D.P.4
-
7
-
-
4444376317
-
Over 20% of human transcripts might form sense-antisense pairs
-
Chen J., Sun M., Kent W.J., Huang X., Xie H., Wang W., Zhou G., Shi R.Z., and Rowley J.D. Over 20% of human transcripts might form sense-antisense pairs. Nucleic Acids Res. 32 (2004) 4812-4820
-
(2004)
Nucleic Acids Res.
, vol.32
, pp. 4812-4820
-
-
Chen, J.1
Sun, M.2
Kent, W.J.3
Huang, X.4
Xie, H.5
Wang, W.6
Zhou, G.7
Shi, R.Z.8
Rowley, J.D.9
-
8
-
-
22144461002
-
miRNAs, cancer, and stem cell division
-
Croce C.M., and Calin G.A. miRNAs, cancer, and stem cell division. Cell 122 (2005) 6-7
-
(2005)
Cell
, vol.122
, pp. 6-7
-
-
Croce, C.M.1
Calin, G.A.2
-
9
-
-
9144224451
-
Processing of primary microRNAs by the Microprocessor complex
-
Denli A.M., Tops B.B., Plasterk R.H., Ketting R.F., and Hannon G.J. Processing of primary microRNAs by the Microprocessor complex. Nature 432 (2004) 231-235
-
(2004)
Nature
, vol.432
, pp. 231-235
-
-
Denli, A.M.1
Tops, B.B.2
Plasterk, R.H.3
Ketting, R.F.4
Hannon, G.J.5
-
10
-
-
27644582893
-
Probing tumor phenotypes using stable and regulated synthetic microRNA precursors
-
Dickins R.A., Hemann M.T., Zilfou J.T., Simpson D.R., Ibarra I., Hannon G.J., and Lowe S.W. Probing tumor phenotypes using stable and regulated synthetic microRNA precursors. Nat. Genet. 37 (2005) 1289-1295
-
(2005)
Nat. Genet.
, vol.37
, pp. 1289-1295
-
-
Dickins, R.A.1
Hemann, M.T.2
Zilfou, J.T.3
Simpson, D.R.4
Ibarra, I.5
Hannon, G.J.6
Lowe, S.W.7
-
11
-
-
9144225636
-
The Microprocessor complex mediates the genesis of microRNAs
-
Gregory R.I., Yan K.P., Amuthan G., Chendrimada T., Doratotaj B., Cooch N., and Shiekhattar R. The Microprocessor complex mediates the genesis of microRNAs. Nature 432 (2004) 235-240
-
(2004)
Nature
, vol.432
, pp. 235-240
-
-
Gregory, R.I.1
Yan, K.P.2
Amuthan, G.3
Chendrimada, T.4
Doratotaj, B.5
Cooch, N.6
Shiekhattar, R.7
-
12
-
-
17844364875
-
Genes and mechanisms related to RNA interference regulate expression of the small temporal RNAs that control C. elegans developmental timing
-
Grishok A., Pasquinelli A.E., Conte D., Li N., Parrish S., Ha I., Baillie D.L., Fire A., Ruvkun G., and Mello C.C. Genes and mechanisms related to RNA interference regulate expression of the small temporal RNAs that control C. elegans developmental timing. Cell 106 (2001) 23-34
-
(2001)
Cell
, vol.106
, pp. 23-34
-
-
Grishok, A.1
Pasquinelli, A.E.2
Conte, D.3
Li, N.4
Parrish, S.5
Ha, I.6
Baillie, D.L.7
Fire, A.8
Ruvkun, G.9
Mello, C.C.10
-
13
-
-
10644234841
-
The Drosha-DGCR8 complex in primary microRNA processing
-
Han J., Lee Y., Yeom K.H., Kim Y.K., Jin H., and Kim V.N. The Drosha-DGCR8 complex in primary microRNA processing. Genes Dev. 18 (2004) 3016-3027
-
(2004)
Genes Dev.
, vol.18
, pp. 3016-3027
-
-
Han, J.1
Lee, Y.2
Yeom, K.H.3
Kim, Y.K.4
Jin, H.5
Kim, V.N.6
-
14
-
-
0035800521
-
A cellular function for the RNA-interference enzyme Dicer in the maturation of the let-7 small temporal RNA
-
Hutvagner G., McLachlan J., Pasquinelli A.E., Balint E., Tuschl T., and Zamore P.D. A cellular function for the RNA-interference enzyme Dicer in the maturation of the let-7 small temporal RNA. Science 293 (2001) 834-838
-
(2001)
Science
, vol.293
, pp. 834-838
-
-
Hutvagner, G.1
McLachlan, J.2
Pasquinelli, A.E.3
Balint, E.4
Tuschl, T.5
Zamore, P.D.6
-
15
-
-
0035887005
-
Dicer functions in RNA interference and in synthesis of small RNA involved in developmental timing in C. elegans
-
Ketting R.F., Fischer S.E., Bernstein E., Sijen T., Hannon G.J., and Plasterk R.H. Dicer functions in RNA interference and in synthesis of small RNA involved in developmental timing in C. elegans. Genes Dev. 15 (2001) 2654-2659
-
(2001)
Genes Dev.
, vol.15
, pp. 2654-2659
-
-
Ketting, R.F.1
Fischer, S.E.2
Bernstein, E.3
Sijen, T.4
Hannon, G.J.5
Plasterk, R.H.6
-
16
-
-
0142165224
-
Functional siRNAs and miRNAs exhibit strand bias
-
Khvorova A., Reynolds A., and Jayasena S.D. Functional siRNAs and miRNAs exhibit strand bias. Cell 115 (2003) 209-216
-
(2003)
Cell
, vol.115
, pp. 209-216
-
-
Khvorova, A.1
Reynolds, A.2
Jayasena, S.D.3
-
17
-
-
18344369543
-
MicroRNA biogenesis: coordinated cropping and dicing
-
Kim V.N. MicroRNA biogenesis: coordinated cropping and dicing. Nat. Rev. Mol. Cell Biol. 6 (2005) 376-385
-
(2005)
Nat. Rev. Mol. Cell Biol.
, vol.6
, pp. 376-385
-
-
Kim, V.N.1
-
18
-
-
18344373363
-
Small RNAs: Classification, biogenesis, and function
-
Kim V.N. Small RNAs: Classification, biogenesis, and function. Mol. Cells 19 (2005) 1-15
-
(2005)
Mol. Cells
, vol.19
, pp. 1-15
-
-
Kim, V.N.1
-
19
-
-
4744357297
-
Structural features of microRNA (miRNA) precursors and their relevance to miRNA biogenesis and small interfering RNA/short hairpin RNA design
-
Krol J., Sobczak K., Wilczynska U., Drath M., Jasinska A., Kaczynska D., and Krzyzosiak W.J. Structural features of microRNA (miRNA) precursors and their relevance to miRNA biogenesis and small interfering RNA/short hairpin RNA design. J. Biol. Chem. 279 (2004) 42230-42239
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 42230-42239
-
-
Krol, J.1
Sobczak, K.2
Wilczynska, U.3
Drath, M.4
Jasinska, A.5
Kaczynska, D.6
Krzyzosiak, W.J.7
-
20
-
-
10344248903
-
The human DiGeorge syndrome critical region gene 8 and Its D. melanogaster homolog are required for miRNA biogenesis
-
Landthaler M., Yalcin A., and Tuschl T. The human DiGeorge syndrome critical region gene 8 and Its D. melanogaster homolog are required for miRNA biogenesis. Curr. Biol. 14 (2004) 2162-2167
-
(2004)
Curr. Biol.
, vol.14
, pp. 2162-2167
-
-
Landthaler, M.1
Yalcin, A.2
Tuschl, T.3
-
21
-
-
0037009364
-
MicroRNA maturation: stepwise processing and subcellular localization
-
Lee Y., Jeon K., Lee J.T., Kim S., and Kim V.N. MicroRNA maturation: stepwise processing and subcellular localization. EMBO J. 21 (2002) 4663-4670
-
(2002)
EMBO J.
, vol.21
, pp. 4663-4670
-
-
Lee, Y.1
Jeon, K.2
Lee, J.T.3
Kim, S.4
Kim, V.N.5
-
22
-
-
0141843656
-
The nuclear RNase III Drosha initiates microRNA processing
-
Lee Y., Ahn C., Han J., Choi H., Kim J., Yim J., Lee J., Provost P., Radmark O., Kim S., and Kim V.N. The nuclear RNase III Drosha initiates microRNA processing. Nature 425 (2003) 415-419
-
(2003)
Nature
, vol.425
, pp. 415-419
-
-
Lee, Y.1
Ahn, C.2
Han, J.3
Choi, H.4
Kim, J.5
Yim, J.6
Lee, J.7
Provost, P.8
Radmark, O.9
Kim, S.10
Kim, V.N.11
-
23
-
-
8144225486
-
MicroRNA genes are transcribed by RNA polymerase II
-
Lee Y., Kim M., Han J., Yeom K.H., Lee S., Baek S.H., and Kim V.N. MicroRNA genes are transcribed by RNA polymerase II. EMBO J. 23 (2004) 4051-4060
-
(2004)
EMBO J.
, vol.23
, pp. 4051-4060
-
-
Lee, Y.1
Kim, M.2
Han, J.3
Yeom, K.H.4
Lee, S.5
Baek, S.H.6
Kim, V.N.7
-
25
-
-
20444460289
-
MicroRNA expression profiles classify human cancers
-
Lu J., Getz G., Miska E.A., Alvarez-Saavedra E., Lamb J., Peck D., Sweet-Cordero A., Ebert B.L., Mak R.H., Ferrando A.A., et al. MicroRNA expression profiles classify human cancers. Nature 435 (2005) 834-838
-
(2005)
Nature
, vol.435
, pp. 834-838
-
-
Lu, J.1
Getz, G.2
Miska, E.A.3
Alvarez-Saavedra, E.4
Lamb, J.5
Peck, D.6
Sweet-Cordero, A.7
Ebert, B.L.8
Mak, R.H.9
Ferrando, A.A.10
-
26
-
-
0347988235
-
Nuclear export of microRNA precursors
-
Lund E., Guttinger S., Calado A., Dahlberg J.E., and Kutay U. Nuclear export of microRNA precursors. Science 303 (2004) 95-98
-
(2004)
Science
, vol.303
, pp. 95-98
-
-
Lund, E.1
Guttinger, S.2
Calado, A.3
Dahlberg, J.E.4
Kutay, U.5
-
27
-
-
2442679207
-
Structural basis for overhang-specific small interfering RNA recognition by the PAZ domain
-
Ma J.B., Ye K., and Patel D.J. Structural basis for overhang-specific small interfering RNA recognition by the PAZ domain. Nature 429 (2004) 318-322
-
(2004)
Nature
, vol.429
, pp. 318-322
-
-
Ma, J.B.1
Ye, K.2
Patel, D.J.3
-
28
-
-
30844438338
-
Structural basis for double-stranded RNA processing by Dicer
-
Macrae I.J., Zhou K., Li F., Repic A., Brooks A.N., Cande W.Z., Adams P.D., and Doudna J.A. Structural basis for double-stranded RNA processing by Dicer. Science 311 (2006) 195-198
-
(2006)
Science
, vol.311
, pp. 195-198
-
-
Macrae, I.J.1
Zhou, K.2
Li, F.3
Repic, A.4
Brooks, A.N.5
Cande, W.Z.6
Adams, P.D.7
Doudna, J.A.8
-
29
-
-
0033591465
-
Expanded sequence dependence of thermodynamic parameters improves prediction of RNA secondary structure
-
Mathews D.H., Sabina J., Zuker M., and Turner D.H. Expanded sequence dependence of thermodynamic parameters improves prediction of RNA secondary structure. J. Mol. Biol. 288 (1999) 911-940
-
(1999)
J. Mol. Biol.
, vol.288
, pp. 911-940
-
-
Mathews, D.H.1
Sabina, J.2
Zuker, M.3
Turner, D.H.4
-
30
-
-
10744225153
-
Asymmetry in the assembly of the RNAi enzyme complex
-
Schwarz D.S., Hutvagner G., Du T., Xu Z., Aronin N., and Zamore P.D. Asymmetry in the assembly of the RNAi enzyme complex. Cell 115 (2003) 199-208
-
(2003)
Cell
, vol.115
, pp. 199-208
-
-
Schwarz, D.S.1
Hutvagner, G.2
Du, T.3
Xu, Z.4
Aronin, N.5
Zamore, P.D.6
-
31
-
-
27644436787
-
Second-generation shRNA libraries covering the mouse and human genomes
-
Silva J.M., Li M.Z., Chang K., Ge W., Golding M.C., Rickles R.J., Siolas D., Hu G., Paddison P.J., Schlabach M.R., et al. Second-generation shRNA libraries covering the mouse and human genomes. Nat. Genet. 37 (2005) 1281-1288
-
(2005)
Nat. Genet.
, vol.37
, pp. 1281-1288
-
-
Silva, J.M.1
Li, M.Z.2
Chang, K.3
Ge, W.4
Golding, M.C.5
Rickles, R.J.6
Siolas, D.7
Hu, G.8
Paddison, P.J.9
Schlabach, M.R.10
-
32
-
-
0345490960
-
The crystal structure of the Argonaute2 PAZ domain reveals an RNA binding motif in RNAi effector complexes
-
Song J.J., Liu J., Tolia N.H., Schneiderman J., Smith S.K., Martienssen R.A., Hannon G.J., and Joshua-Tor L. The crystal structure of the Argonaute2 PAZ domain reveals an RNA binding motif in RNAi effector complexes. Nat. Struct. Biol. 10 (2003) 1026-1032
-
(2003)
Nat. Struct. Biol.
, vol.10
, pp. 1026-1032
-
-
Song, J.J.1
Liu, J.2
Tolia, N.H.3
Schneiderman, J.4
Smith, S.K.5
Martienssen, R.A.6
Hannon, G.J.7
Joshua-Tor, L.8
-
33
-
-
12544258104
-
MicroRNA biogenesis: Drosha can't cut it without a partner
-
Tomari Y., and Zamore P.D. MicroRNA biogenesis: Drosha can't cut it without a partner. Curr. Biol. 15 (2005) R61-R64
-
(2005)
Curr. Biol.
, vol.15
-
-
Tomari, Y.1
Zamore, P.D.2
-
34
-
-
17844363243
-
The contributions of dsRNA structure to Dicer specificity and efficiency
-
Vermeulen A., Behlen L., Reynolds A., Wolfson A., Marshall W.S., Karpilow J., and Khvorova A. The contributions of dsRNA structure to Dicer specificity and efficiency. RNA 11 (2005) 674-682
-
(2005)
RNA
, vol.11
, pp. 674-682
-
-
Vermeulen, A.1
Behlen, L.2
Reynolds, A.3
Wolfson, A.4
Marshall, W.S.5
Karpilow, J.6
Khvorova, A.7
-
35
-
-
0642345790
-
Structure and conserved RNA binding of the PAZ domain
-
Yan K.S., Yan S., Farooq A., Han A., Zeng L., and Zhou M.M. Structure and conserved RNA binding of the PAZ domain. Nature 426 (2003) 468-474
-
(2003)
Nature
, vol.426
, pp. 468-474
-
-
Yan, K.S.1
Yan, S.2
Farooq, A.3
Han, A.4
Zeng, L.5
Zhou, M.M.6
-
36
-
-
2142654329
-
MicroRNA-directed cleavage of HOXB8 mRNA
-
Yekta S., Shih I.H., and Bartel D.P. MicroRNA-directed cleavage of HOXB8 mRNA. Science 304 (2004) 594-596
-
(2004)
Science
, vol.304
, pp. 594-596
-
-
Yekta, S.1
Shih, I.H.2
Bartel, D.P.3
-
37
-
-
12244275645
-
Widespread occurrence of antisense transcription in the human genome
-
Yelin R., Dahary D., Sorek R., Levanon E.Y., Goldstein O., Shoshan A., Diber A., Biton S., Tamir Y., Khosravi R., et al. Widespread occurrence of antisense transcription in the human genome. Nat. Biotechnol. 21 (2003) 379-386
-
(2003)
Nat. Biotechnol.
, vol.21
, pp. 379-386
-
-
Yelin, R.1
Dahary, D.2
Sorek, R.3
Levanon, E.Y.4
Goldstein, O.5
Shoshan, A.6
Diber, A.7
Biton, S.8
Tamir, Y.9
Khosravi, R.10
-
38
-
-
0347361541
-
Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs
-
Yi R., Qin Y., Macara I.G., and Cullen B.R. Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs. Genes Dev. 17 (2003) 3011-3016
-
(2003)
Genes Dev.
, vol.17
, pp. 3011-3016
-
-
Yi, R.1
Qin, Y.2
Macara, I.G.3
Cullen, B.R.4
-
39
-
-
23044502585
-
Efficient processing of primary microRNA hairpins by Drosha requires flanking nonstructured RNA sequences
-
Zeng Y., and Cullen B.R. Efficient processing of primary microRNA hairpins by Drosha requires flanking nonstructured RNA sequences. J. Biol. Chem. 280 (2005) 27595-27603
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 27595-27603
-
-
Zeng, Y.1
Cullen, B.R.2
-
40
-
-
0036294527
-
Both natural and designed micro RNAs can inhibit the expression of cognate mRNAs when expressed in human cells
-
Zeng Y., Wagner E.J., and Cullen B.R. Both natural and designed micro RNAs can inhibit the expression of cognate mRNAs when expressed in human cells. Mol. Cell 9 (2002) 1327-1333
-
(2002)
Mol. Cell
, vol.9
, pp. 1327-1333
-
-
Zeng, Y.1
Wagner, E.J.2
Cullen, B.R.3
-
41
-
-
12544255565
-
Recognition and cleavage of primary microRNA precursors by the nuclear processing enzyme Drosha
-
Zeng Y., Yi R., and Cullen B.R. Recognition and cleavage of primary microRNA precursors by the nuclear processing enzyme Drosha. EMBO J. 24 (2005) 138-148
-
(2005)
EMBO J.
, vol.24
, pp. 138-148
-
-
Zeng, Y.1
Yi, R.2
Cullen, B.R.3
-
42
-
-
0036845374
-
Human Dicer preferentially cleaves dsRNAs at their termini without a requirement for ATP
-
Zhang H., Kolb F.A., Brondani V., Billy E., and Filipowicz W. Human Dicer preferentially cleaves dsRNAs at their termini without a requirement for ATP. EMBO J. 21 (2002) 5875-5885
-
(2002)
EMBO J.
, vol.21
, pp. 5875-5885
-
-
Zhang, H.1
Kolb, F.A.2
Brondani, V.3
Billy, E.4
Filipowicz, W.5
-
43
-
-
3142613181
-
Single processing center models for human Dicer and bacterial RNase III
-
Zhang H., Kolb F.A., Jaskiewicz L., Westhof E., and Filipowicz W. Single processing center models for human Dicer and bacterial RNase III. Cell 118 (2004) 57-68
-
(2004)
Cell
, vol.118
, pp. 57-68
-
-
Zhang, H.1
Kolb, F.A.2
Jaskiewicz, L.3
Westhof, E.4
Filipowicz, W.5
-
44
-
-
0042121256
-
Mfold web server for nucleic acid folding and hybridization prediction
-
Zuker M. Mfold web server for nucleic acid folding and hybridization prediction. Nucleic Acids Res. 31 (2003) 3406-3415
-
(2003)
Nucleic Acids Res.
, vol.31
, pp. 3406-3415
-
-
Zuker, M.1
|