The let-7 MicroRNA family members mir-48, mir-84, and mir-241 function together to regulate developmental timing in Caenorhabditis elegans

Developmental Cell

Volumn 9, Issue 3, 2005, Pages 403-414

  Abbott, Allison L ^a   Alvarez Saavedra, Ezequiel ^b   Miska, Eric A ^b,d   Lau, Nelson C ^c,e   Bartel, David P ^c   Horvitz, H Robert ^b   Ambros, Victor ^a  

^a DARTMOUTH MEDICAL SCHOOL   (United States)

^b HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^c WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH   (United States)

^d UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^e MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MICRORNA;

3' UNTRANSLATED REGION; ANIMAL TISSUE; ARTICLE; BASE PAIRING; CAENORHABDITIS ELEGANS; CONTROLLED STUDY; DEVELOPMENTAL STAGE; DOWN REGULATION; GENE FUNCTION; GENETIC ANALYSIS; LARVAL DEVELOPMENT; MOLTING; MULTIGENE FAMILY; MUTANT; NONHUMAN; PRIORITY JOURNAL; REGULATORY MECHANISM;

ANIMALS; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; GENE DELETION; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENOTYPE; MICRORNAS; MUTATION; PHYLOGENY; TIME FACTORS;

ANIMALIA; CAENORHABDITIS ELEGANS;

EID: 24144494563     PISSN: 15345807     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.devcel.2005.07.009     Document Type: Article

References (53)

1. J.E. Abrahante E.A. Miller and A.E. Rougvie Identification of heterochronic mutants in Caenorhabditis elegans. Temporal misexpression of a collagen: green fluorescent protein fusion gene Genetics 149 1998 1335-1351
2. J.E. Abrahante A.L. Daul M. Li M.L. Volk J.M. Tennessen E.A. Miller and A.E. Rougvie The Caenorhabditis elegans hunchback-like gene lin-57/hbl-1 controls developmental time and is regulated by microRNAs Dev. Cell 4 2003 625-637
3. V. Ambros A hierarchy of regulatory genes controls a larva-to-adult developmental switch in C. elegans Cell 57 1989 49-57
4. V. Ambros and H.R. Horvitz Heterochronic mutants of the nematode Caenorhabditis elegans Science 226 1984 409-416
5. V. Ambros R.C. Lee A. Lavanway P.T. Williams and D. Jewell MicroRNAs and other tiny endogenous RNAs in C. elegans Curr. Biol. 13 2003 807-818
6. C.I. Bargmann E. Hartwieg and H.R. Horvitz Odorant-selective genes and neurons mediate olfaction in C. elegans Cell 74 1993 515-527
7. D.P. Bartel MicroRNAs: Genomics, biogenesis, mechanism, and function Cell 116 2004 281-297
8. M.A. Behlke S.A. Dames W.H. McDonald K.L. Gould E.J. Devor and J.A. Walder Use of high specific activity StarFire oligonucleotide probes to visualize low-abundance pre-mRNA splicing intermediates in S. pombe Biotechniques 29 2000 892-897
9. G.J. Beitel S.G. Clark and H.R. Horvitz Caenorhabditis elegans ras gene let-60 acts as a switch in the pathway of vulval induction Nature 348 1990 503-509
10. E. Berezikov V. Guryev J. van de Belt E. Wienholds R.H. Plasterk and E. Cuppen Phylogenetic shadowing and computational identification of human microRNA genes Cell 120 2005 21-24
11. J. Brennecke A. Stark R.B. Russell and S.M. Cohen Principles of microRNA-target recognition PLoS Biol. 3 2005 e85
12. S. Brenner The genetics of Caenorhabditis elegans Genetics 77 1974 71-94
13. J.G. Doench and P.A. Sharp Specificity of microRNA target selection in translational repression Genes Dev. 18 2004 504-511
14. M. Edgley A. D'Souza G. Moulder S. McKay B. Shen E. Gilchrist and D. Moerman R. Barstead Improved detection of small deletions in complex pools of DNA Nucleic Acids Res. 30 2002 e52
15. D.S. Fay H.M. Stanley M. Han and W.B. Wood A Caenorhabditis elegans homologue of hunchback is required for late stages of development but not early embryonic patterning Dev. Biol. 205 1999 240-253
16. A.G. Fraser R.S. Kamath P. Zipperlen M. Martinez-Campos M. Sohrmann and J. Ahringer Functional genomic analysis of C. elegans chromosome I by systematic RNA interference Nature 408 2000 325-330
17. Y. Grad J. Aach G.D. Hayes B.J. Reinhart G.M. Church G. Ruvkun and J. Kim Computational and experimental identification of C. elegans microRNAs Mol. Cell 11 2003 1253-1263
18. H. Grosshans T. Johnson K.L. Reinert M. Gerstein and F.J. Slack The temporal patterning microRNA let-7 regulates several transcription factors at the larval to adult transition in C. elegans Dev. Cell 8 2005 321-330
19. M. Han and P.W. Sternberg Let-60, a gene that specifies cell fates during C. elegans vulval induction, encodes a ras protein Cell 63 1990 921-931
20. E.M. Hedgecock and R.K. Herman The ncl-1 gene and genetic mosaics of Caenorhabditis elegans Genetics 141 1995 989-1006
21. R.K. Herman and E.M. Hedgecock Limitation of the size of the vulval primordium of Caenorhabditis elegans by lin-15 expression in surrounding hypodermis Nature 348 1990 169-171
22. G. Jansen E. Hazendonk K.L. Thijssen and R.H. Plasterk Reverse genetics by chemical mutagenesis in Caenorhabditis elegans Nat. Genet. 17 1997 119-121
23. S.M. Johnson H. Grosshans J. Shingara M. Byrom R. Jarvis A. Cheng E. Labourier K.L. Reinert D. Brown and F.J. Slack RAS is regulated by the let-7 microRNA family Cell 120 2005 635-647
24. R.S. Kamath and J. Ahringer Genome-wide RNAi screening in Caenorhabditis elegans Methods 30 2003 313-321
25. W.P. Kloosterman E. Wienholds R.F. Ketting and R.H. Plasterk Substrate requirements for let-7 function in the developing zebrafish embryo Nucleic Acids Res. 32 2004 6284-6291
26. E.C. Lai Micro RNAs are complementary to 3′ UTR sequence motifs that mediate negative post-transcriptional regulation Nat. Genet. 30 2002 363-364
27. N.C. Lau L.P. Lim E.G. Weinstein and D.P. Bartel An abundant class of tiny RNAs with probable regulatory roles in Caenorhabditis elegans Science 294 2001 858-862
28. R.C. Lee and V. Ambros An extensive class of small RNAs in Caenorhabditis elegans Science 294 2001 862-864
29. R.C. Lee R.L. Feinbaum and V. Ambros The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14 Cell 75 1993 843-854
30. B.P. Lewis I.H. Shih M.W. Jones-Rhoades D.P. Bartel and C.B. Burge Prediction of mammalian microRNA targets Cell 115 2003 787-798
31. B.P. Lewis C.B. Burge and D.P. Bartel Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets Cell 120 2005 15-20
32. L.P. Lim N.C. Lau E.G. Weinstein A. Abdelhakim S. Yekta M.W. Rhoades C.B. Burge and D.P. Bartel The microRNAs of Caenorhabditis elegans Genes Dev. 17 2003 991-1008
33. L.P. Lim N.C. Lau P. Garrett-Engele A. Grimson J.M. Schelter J. Castle D.P. Bartel P.S. Linsley and J.M. Johnson Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs Nature 433 2005 769-773
34. S.Y. Lin S.M. Johnson M. Abraham M.C. Vella A. Pasquinelli C. Gamberi E. Gottlieb and F.J. Slack The C. elegans hunchback homolog, hbl-1, controls temporal patterning and is a probable microRNA target Dev. Cell 4 2003 639-650
35. L.X. Liu J.M. Spoerke E.L. Mulligan J. Chen B. Reardon B. Westlund L. Sun K. Abel B. Armstrong and G. Hardiman High-throughput isolation of Caenorhabditis elegans deletion mutants Genome Res. 9 1999 859-867
36. Z. Liu S. Kirch and V. Ambros The Caenorhabditis elegans heterochronic gene pathway controls stage-specific transcription of collagen genes Development 121 1995 2471-2478
37. A.C. Mallory B.J. Reinhart M.W. Jones-Rhoades G. Tang P.D. Zamore M.K. Barton and D.P. Bartel MicroRNA control of PHABULOSA in leaf development: Importance of pairing to the microRNA 5′ region EMBO J. 23 2004 3356-3364
38. C.C. Mello and A. Fire DNA transformation H.F. Epstein D.C. Shakes eds. In: Methods in Cell Biology: Caenorhabditis elegans: Modern Biological Analysis of an Organism 1995 Academic Press San Diego, CA 451-482
39. E.G. Moss R.C. Lee and V. Ambros The cold shock domain protein LIN-28 controls developmental timing in C. elegans and is regulated by the lin-4 RNA Cell 88 1997 637-646
40. T.R. Myers and I. Greenwald Lin-35 Rb Acts in the major hypodermis to oppose Ras-mediated vulval induction in C. elegans Dev. Cell 8 2005 117-123
41. U. Ohler S. Yekta L.P. Lim D.P. Bartel and C.B. Burge Patterns of flanking sequence conservation and a characteristic upstream motif for microRNA gene identification RNA 10 2004 1309-1322
42. A.E. Pasquinelli B.J. Reinhart F. Slack M.Q. Martindale M.I. Kuroda B. Maller D.C. Hayward E.E. Ball B. Degnan and P. Muller Conservation of the sequence and temporal expression of let-7 heterochronic regulatory RNA Nature 408 2000 86-89
43. A.S. Pepper J.E. McCane K. Kemper D.A. Yeung R.C. Lee V. Ambros and E.G. Moss The C. elegans heterochronic gene lin-46 affects developmental timing at two larval stages and encodes a relative of the scaffolding protein gephyrin Development 131 2004 2049-2059
44. B.J. Reinhart F.J. Slack M. Basson A.E. Pasquinelli J.C. Bettinger A.E. Rougvie H.R. Horvitz and G. Ruvkun The 21-nucleotide let-7 RNA regulates developmental timing in Caenorhabditis elegans Nature 403 2000 901-906
45. A.E. Rougvie Control of developmental timing in animals Nat. Rev. Genet. 2 2001 690-701
46. K. Seggerson L. Tang and E.G. Moss Two genetic circuits repress the Caenorhabditis elegans heterochronic gene lin-28 after translation initiation Dev. Biol. 243 2002 215-225
47. F.J. Slack M. Basson Z. Liu V. Ambros H.R. Horvitz and G. Ruvkun The lin-41 RBCC gene acts in the C. elegans heterochronic pathway between the let-7 regulatory RNA and the LIN-29 transcription factor Mol. Cell 5 2000 659-669
48. A. Stark J. Brennecke R.B. Russell and S.M. Cohen Identification of Drosophila MicroRNA targets PLoS Biol. 1 2003 E60
49. J.E. Sulston and H.R. Horvitz Post-embryonic cell lineages of the nematode, Caenorhabditis elegans Dev. Biol. 56 1977 110-156
50. L. Timmons D.L. Court and A. Fire Ingestion of bacterially expressed dsRNAs can produce specific and potent genetic interference in Caenorhabditis elegans Gene 263 2001 103-112
51. M.C. Vella E.Y. Choi S.Y. Lin K. Reinert and F.J. Slack The C. elegans microRNA let-7 binds to imperfect let-7 complementary sites from the lin-41 3′UTR Genes Dev. 18 2004 132-137
52. B. Wightman I. Ha G. Ruvkun Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegans Cell 75 1993 855-862
53. Wood, W.B., and the Community of C. elegans Researchers (1988). Nematode Caenorhabditis elegans (Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press).