메뉴 건너뛰기




Volumn 21, Issue 21, 2002, Pages 5864-5874

Ribonuclease activity and RNA binding of recombinant human Dicer

Author keywords

Dicer; dsRNA; Ribonuclease III; RNA binding; RNA processing

Indexed keywords

ADENOSINE TRIPHOSPHATE; CALRETICULIN; DICER; DOUBLE STRANDED RNA; MAGNESIUM; POTASSIUM CHLORIDE; RECOMBINANT PROTEIN; RIBONUCLEASE; UNCLASSIFIED DRUG;

EID: 0036847540     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/cdf578     Document Type: Article
Times cited : (380)

References (52)
  • 1
    • 0029919935 scopus 로고    scopus 로고
    • RNase III cleaves eukaryotic preribosomal RNA at a U3 snoRNP-dependent site
    • Abou Elela, S., Igel, H. and Ares, M., Jr (1996) RNase III cleaves eukaryotic preribosomal RNA at a U3 snoRNP-dependent site. Cell, 85, 115-124.
    • (1996) Cell , vol.85 , pp. 115-124
    • Abou Elela, S.1    Igel, H.2    Ares, M.3
  • 2
    • 0034724519 scopus 로고    scopus 로고
    • Double-stranded RNA as a template for gene silencing
    • Bass, B.L. (2000) Double-stranded RNA as a template for gene silencing. Cell, 101, 235-238.
    • (2000) Cell , vol.101 , pp. 235-238
    • Bass, B.L.1
  • 3
    • 0030267493 scopus 로고    scopus 로고
    • RNA as a target and an initiator of posttranscriptional gene silencing in transgenic plants
    • Baulcombe, D.C. (1996) RNA as a target and an initiator of posttranscriptional gene silencing in transgenic plants. Plant Mol. Biol., 32, 79-88.
    • (1996) Plant Mol. Biol. , vol.32 , pp. 79-88
    • Baulcombe, D.C.1
  • 4
    • 0035905766 scopus 로고    scopus 로고
    • Role for a bidentate ribonuclease in the initiation step of RNA interference
    • Bernstein, E., Caudy, A.A., Hammond, S.M. and Hannon, G.J. (2001) Role for a bidentate ribonuclease in the initiation step of RNA interference. Nature, 409, 363-366.
    • (2001) Nature , vol.409 , pp. 363-366
    • Bernstein, E.1    Caudy, A.A.2    Hammond, S.M.3    Hannon, G.J.4
  • 5
    • 0035807818 scopus 로고    scopus 로고
    • Specific interference with gene expression induced by long, double-stranded RNA in mouse embryonal teratocarcinoma cell lines
    • Billy, E., Brondani, V., Zhang, H., Muller, U. and Filipowicz, W. (2001) Specific interference with gene expression induced by long, double-stranded RNA in mouse embryonal teratocarcinoma cell lines. Proc. Natl. Acad. Sci. USA, 98, 14428-14433.
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 14428-14433
    • Billy, E.1    Brondani, V.2    Zhang, H.3    Muller, U.4    Filipowicz, W.5
  • 6
    • 0035662491 scopus 로고    scopus 로고
    • Crystallographic and modeling studies of RNase III suggest a mechanism for double-stranded RNA cleavage
    • Blaszczyk, J., Tropea, J.E., Bubunenko, M., Routzahn, K.M., Waugh, D.S., Court, D.L. and Ji, X. (2001) Crystallographic and modeling studies of RNase III suggest a mechanism for double-stranded RNA cleavage. Structure (Camb.), 9, 1225-1236.
    • (2001) Structure (Camb.) , vol.9 , pp. 1225-1236
    • Blaszczyk, J.1    Tropea, J.E.2    Bubunenko, M.3    Routzahn, K.M.4    Waugh, D.S.5    Court, D.L.6    Ji, X.7
  • 7
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • Bradford, M.M. (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem., 72, 248-254.
    • (1976) Anal. Biochem. , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 8
    • 0030859441 scopus 로고    scopus 로고
    • Alternative 3′-end processing of U5 snRNA by RNase III
    • Chanfreau, G., Abou Elela, S., Ares, M., Jr and Guthrie, C. (1997) Alternative 3′-end processing of U5 snRNA by RNase III. Genes Dev., 11, 2741-2751.
    • (1997) Genes Dev. , vol.11 , pp. 2741-2751
    • Chanfreau, G.1    Abou Elela, S.2    Ares, M.3    Guthrie, C.4
  • 9
    • 0032189582 scopus 로고    scopus 로고
    • Different cleavage specificities of RNases III from Rhodobacter capsulatus and Escherichia coli
    • Conrad, C., Rauhut, R. and Klug, G. (1998) Different cleavage specificities of RNases III from Rhodobacter capsulatus and Escherichia coli. Nucleic Acids Res., 26, 4446-4453.
    • (1998) Nucleic Acids Res. , vol.26 , pp. 4446-4453
    • Conrad, C.1    Rauhut, R.2    Klug, G.3
  • 10
    • 34250257369 scopus 로고
    • RNA processing and degradation by RNase III
    • Belasco, J.G. and Brawerman, G. (eds). Academic Press, San Diego, CA
    • Court, D. (1993) RNA processing and degradation by RNase III. In Belasco, J.G. and Brawerman, G. (eds), Control of Messenger RNA Stability. Academic Press, San Diego, CA, pp. 71-116.
    • (1993) Control of Messenger RNA Stability , pp. 71-116
    • Court, D.1
  • 11
    • 0035942736 scopus 로고    scopus 로고
    • Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells
    • Elbashir, S.M., Harborth, J., Lendeckel, W., Yalcin, A., Weber, K. and Tuschl, T. (2001a) Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells. Nature, 411, 494-498.
    • (2001) Nature , vol.411 , pp. 494-498
    • Elbashir, S.M.1    Harborth, J.2    Lendeckel, W.3    Yalcin, A.4    Weber, K.5    Tuschl, T.6
  • 12
    • 0035863097 scopus 로고    scopus 로고
    • RNA interference is mediated by 21- and 22-nucleotide RNAs
    • Elbashir, S.M., Lendeckel, W. and Tuschl, T. (2001b) RNA interference is mediated by 21- and 22-nucleotide RNAs. Genes Dev., 15, 188-200.
    • (2001) Genes Dev. , vol.15 , pp. 188-200
    • Elbashir, S.M.1    Lendeckel, W.2    Tuschl, T.3
  • 13
    • 0032545933 scopus 로고    scopus 로고
    • Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans
    • Fire, A., Xu, S., Montgomery, M.K., Kostas, S.A., Driver, S.E. and Mello, C.C. (1998) Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature, 391, 806-811.
    • (1998) Nature , vol.391 , pp. 806-811
    • Fire, A.1    Xu, S.2    Montgomery, M.K.3    Kostas, S.A.4    Driver, S.E.5    Mello, C.C.6
  • 14
    • 17844364875 scopus 로고    scopus 로고
    • Genes and mechanisms related to RNA interference regulate expression of the small temporal RNAs that control C. elegans developmental timing
    • Grishok, A. et al. (2001) Genes and mechanisms related to RNA interference regulate expression of the small temporal RNAs that control C. elegans developmental timing. Cell, 106, 23-34.
    • (2001) Cell , vol.106 , pp. 23-34
    • Grishok, A.1
  • 15
    • 0034673638 scopus 로고    scopus 로고
    • An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells
    • Hammond, S.M., Bernstein, E., Beach, D. and Hannon, G.J. (2000) An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells. Nature, 404, 293-296.
    • (2000) Nature , vol.404 , pp. 293-296
    • Hammond, S.M.1    Bernstein, E.2    Beach, D.3    Hannon, G.J.4
  • 16
    • 0035261255 scopus 로고    scopus 로고
    • Posttranscriptional gene silencing by double-stranded RNA
    • Hammond, S.M., Caudy, A.A. and Hannon, G.J. (2001) Posttranscriptional gene silencing by double-stranded RNA. Nat. Rev. Genet., 2, 110-119.
    • (2001) Nat. Rev. Genet. , vol.2 , pp. 110-119
    • Hammond, S.M.1    Caudy, A.A.2    Hannon, G.J.3
  • 18
    • 0035800521 scopus 로고    scopus 로고
    • A cellular function for the RNA-interference enzyme Dicer in the maturation of the let-7 small temporal RNA
    • Hutvágner, G., McLachlan, J., Pasquinelli, A.E., Balint, E., Tuschl, T. and Zamore, P.D. (2001) A cellular function for the RNA-interference enzyme Dicer in the maturation of the let-7 small temporal RNA. Science, 293, 834-838.
    • (2001) Science , vol.293 , pp. 834-838
    • Hutvágner, G.1    McLachlan, J.2    Pasquinelli, A.E.3    Balint, E.4    Tuschl, T.5    Zamore, P.D.6
  • 19
    • 0026089369 scopus 로고
    • +, whose overexpression inhibits sexual development, encodes a ribonuclease III-like RNase
    • +, whose overexpression inhibits sexual development, encodes a ribonuclease III-like RNase. EMBO J., 10, 221-226.
    • (1991) EMBO J. , vol.10 , pp. 221-226
    • Iino, Y.1    Sugimoto, A.2    Yamamoto, M.3
  • 20
    • 0033385170 scopus 로고    scopus 로고
    • Disruption of an RNA helicase/RNase III gene in Arabidopsis causes unregulated cell division in floral meristems
    • Jacobsen, S.E., Running, M.P. and Meyerowitz, E.M. (1999) Disruption of an RNA helicase/RNase III gene in Arabidopsis causes unregulated cell division in floral meristems. Development, 126, 5231-5243.
    • (1999) Development , vol.126 , pp. 5231-5243
    • Jacobsen, S.E.1    Running, M.P.2    Meyerowitz, E.M.3
  • 21
    • 0035887005 scopus 로고    scopus 로고
    • Dicer functions in RNA interference and in synthesis of small RNA involved in developmental timing in C. elegans
    • Ketting, R.F., Fischer, S.E., Bernstein, E., Sijen, T., Hannon, G.J. and Plasterk, R.H. (2001) Dicer functions in RNA interference and in synthesis of small RNA involved in developmental timing in C. elegans. Genes Dev., 15, 2654-2659.
    • (2001) Genes Dev. , vol.15 , pp. 2654-2659
    • Ketting, R.F.1    Fischer, S.E.2    Bernstein, E.3    Sijen, T.4    Hannon, G.J.5    Plasterk, R.H.6
  • 22
    • 0035929322 scopus 로고    scopus 로고
    • A role for the RNase III enzyme DCR-1 in RNA interference and germ line development in Caenorhabditis elegans
    • Knight, S.W. and Bass, B.L. (2001) A role for the RNase III enzyme DCR-1 in RNA interference and germ line development in Caenorhabditis elegans. Science, 293, 2269-2271.
    • (2001) Science , vol.293 , pp. 2269-2271
    • Knight, S.W.1    Bass, B.L.2
  • 23
    • 0023665902 scopus 로고
    • An analysis of 5′-noncoding sequences from 699 vertebrate messenger RNAs
    • Kozak, M. (1987) An analysis of 5′-noncoding sequences from 699 vertebrate messenger RNAs. Nucleic Acids Res., 15, 8125-8148.
    • (1987) Nucleic Acids Res. , vol.15 , pp. 8125-8148
    • Kozak, M.1
  • 24
    • 0035955374 scopus 로고    scopus 로고
    • Identification of novel genes coding for small expressed RNAs
    • Lagos-Quintana, M., Rauhut, R., Lendeckel, W. and Tuschl, T. (2001) Identification of novel genes coding for small expressed RNAs. Science, 294, 853-858.
    • (2001) Science , vol.294 , pp. 853-858
    • Lagos-Quintana, M.1    Rauhut, R.2    Lendeckel, W.3    Tuschl, T.4
  • 25
    • 0035955361 scopus 로고    scopus 로고
    • An abundant class of tiny RNAs with probable regulatory roles in Caenorhabditis elegans
    • Lau, N.C., Lim, L.P., Weinstein, E.G. and Bartel, D.P. (2001) An abundant class of tiny RNAs with probable regulatory roles in Caenorhabditis elegans. Science, 294, 858-862.
    • (2001) Science , vol.294 , pp. 858-862
    • Lau, N.C.1    Lim, L.P.2    Weinstein, E.G.3    Bartel, D.P.4
  • 26
    • 0035955366 scopus 로고    scopus 로고
    • An extensive class of small RNAs in Caenorhabditis elegans
    • Lee, R.C. and Ambros, V. (2001) An extensive class of small RNAs in Caenorhabditis elegans. Science, 294, 862-864.
    • (2001) Science , vol.294 , pp. 862-864
    • Lee, R.C.1    Ambros, V.2
  • 27
    • 0027191132 scopus 로고
    • Ribonuclease III cleavage of a bacteriophage T7 processing signal. Divalent cation specificity, and specific anion effects
    • Li, H.L., Chelladurai, B.S., Zhang, K. and Nicholson, A.W. (1993) Ribonuclease III cleavage of a bacteriophage T7 processing signal. Divalent cation specificity, and specific anion effects. Nucleic Acids Res., 21, 1919-1925.
    • (1993) Nucleic Acids Res. , vol.21 , pp. 1919-1925
    • Li, H.L.1    Chelladurai, B.S.2    Zhang, K.3    Nicholson, A.W.4
  • 28
    • 0033979493 scopus 로고    scopus 로고
    • Molecular cloning and characterization of a novel human gene (HERNA) which encodes a putative RNA-helicase
    • Matsuda, S., Ichigotani, Y., Okuda, T., Irimura, T., Nakatsugawa, S. and Hamaguchi, M. (2000) Molecular cloning and characterization of a novel human gene (HERNA) which encodes a putative RNA-helicase. Biochim. Biophys. Acta, 1490, 163-169.
    • (2000) Biochim. Biophys. Acta , vol.1490 , pp. 163-169
    • Matsuda, S.1    Ichigotani, Y.2    Okuda, T.3    Irimura, T.4    Nakatsugawa, S.5    Hamaguchi, M.6
  • 29
    • 0011327145 scopus 로고    scopus 로고
    • Expression of proteins in insect cells using baculovirus vectors
    • Ausubel, F. et al. (eds). John Wiley & Sons, Inc., New York, NY
    • Murphy, C.I., Piwnica-Worms, H., Grunwald, S. and Romanow, W.G. (1997) Expression of proteins in insect cells using baculovirus vectors. In Ausubel, F. et al. (eds), Current Protocols in Molecular Biology. John Wiley & Sons, Inc., New York, NY, pp. 16.9.1-16.9.10.
    • (1997) Current Protocols in Molecular Biology , pp. 1691-16910
    • Murphy, C.I.1    Piwnica-Worms, H.2    Grunwald, S.3    Romanow, W.G.4
  • 30
    • 0036147007 scopus 로고    scopus 로고
    • Molecular characterization of a mouse cDNA encoding Dicer, a ribonuclease III ortholog involved in RNA interference
    • Nicholson, R.H. and Nicholson, A.W. (2002) Molecular characterization of a mouse cDNA encoding Dicer, a ribonuclease III ortholog involved in RNA interference. Mamm. Genome, 13, 67-73.
    • (2002) Mamm. Genome , vol.13 , pp. 67-73
    • Nicholson, R.H.1    Nicholson, A.W.2
  • 31
    • 0035798415 scopus 로고    scopus 로고
    • ATP requirements and small interfering RNA structure in the RNA interference pathway
    • Nykänen, A., Haley, B. and Zamore, P.D. (2001) ATP requirements and small interfering RNA structure in the RNA interference pathway. Cell, 107, 309-321.
    • (2001) Cell , vol.107 , pp. 309-321
    • Nykänen, A.1    Haley, B.2    Zamore, P.D.3
  • 32
    • 0034597777 scopus 로고    scopus 로고
    • Conservation of the sequence and temporal expression of let-7 heterochronic regulatory RNA
    • Pasquinelli, A.E. et al. (2000) Conservation of the sequence and temporal expression of let-7 heterochronic regulatory RNA. Nature, 408, 86-89.
    • (2000) Nature , vol.408 , pp. 86-89
    • Pasquinelli, A.E.1
  • 34
    • 0035886877 scopus 로고    scopus 로고
    • Coactosin-like protein, a human F-actin-binding protein: Critical role of lysine-75
    • Provost, P., Doucet, J., Stock, A., Gerisch, G., Samuelsson, B. and Rådmark, O. (2001b) Coactosin-like protein, a human F-actin-binding protein: Critical role of lysine-75. Biochem. J., 359, 255-263.
    • (2001) Biochem. J. , vol.359 , pp. 255-263
    • Provost, P.1    Doucet, J.2    Stock, A.3    Gerisch, G.4    Samuelsson, B.5    Rådmark, O.6
  • 36
    • 0014408286 scopus 로고
    • Purification and properties of ribonuclease III from Escherichia coli
    • Robertson, H.D., Webster, R.E. and Zinder, N.D. (1968) Purification and properties of ribonuclease III from Escherichia coli. J. Biol. Chem., 243, 82-91.
    • (1968) J. Biol. Chem. , vol.243 , pp. 82-91
    • Robertson, H.D.1    Webster, R.E.2    Zinder, N.D.3
  • 37
    • 0026441194 scopus 로고
    • Quelling: Transient inactivation of gene expression in Neurospora crassa by transformation with homologous sequences
    • Romano, N. and Macino, G. (1992) Quelling: Transient inactivation of gene expression in Neurospora crassa by transformation with homologous sequences. Mol. Microbiol., 6, 3343-3353.
    • (1992) Mol. Microbiol. , vol.6 , pp. 3343-3353
    • Romano, N.1    Macino, G.2
  • 38
    • 0029931692 scopus 로고    scopus 로고
    • Purification and characterization of the Pac1 ribonuclease of Schizosaccharomyces pombe
    • Rotondo, G. and Frendewey, D. (1996) Purification and characterization of the Pac1 ribonuclease of Schizosaccharomyces pombe. Nucleic Acids Res., 24, 2377-2386.
    • (1996) Nucleic Acids Res. , vol.24 , pp. 2377-2386
    • Rotondo, G.1    Frendewey, D.2
  • 39
    • 0034809803 scopus 로고    scopus 로고
    • Pac1 ribonuclease of Schizosaccharomyces pombe
    • Rotondo, G. and Frendewey, D. (2001) Pac1 ribonuclease of Schizosaccharomyces pombe. Methods Enzymol., 342, 168-193.
    • (2001) Methods Enzymol. , vol.342 , pp. 168-193
    • Rotondo, G.1    Frendewey, D.2
  • 40
    • 0029021141 scopus 로고
    • Rescue of the fission yeast snRNA synthesis mutant snm1 by overexpression of the double-strand-specific Pac1 ribonuclease
    • Rotondo, G., Gillespie, M. and Frendewey, D. (1995) Rescue of the fission yeast snRNA synthesis mutant snm1 by overexpression of the double-strand-specific Pac1 ribonuclease. Mol. Gen. Genet., 247, 698-708.
    • (1995) Mol. Gen. Genet. , vol.247 , pp. 698-708
    • Rotondo, G.1    Gillespie, M.2    Frendewey, D.3
  • 41
    • 0030761010 scopus 로고    scopus 로고
    • Substrate structure requirements of the Pac1 ribonuclease from Schizosaccharomyces pombe
    • Rotondo, G., Huang, J.Y. and Frendewey, D. (1997) Substrate structure requirements of the Pac1 ribonuclease from Schizosaccharomyces pombe. RNA, 3, 1182-1193.
    • (1997) RNA , vol.3 , pp. 1182-1193
    • Rotondo, G.1    Huang, J.Y.2    Frendewey, D.3
  • 42
    • 0020597565 scopus 로고
    • Leukotrienes: Mediators of immediate hypersensitivity reactions and inflammation
    • Samuelsson, B. (1983) Leukotrienes: Mediators of immediate hypersensitivity reactions and inflammation. Science, 220, 568-575.
    • (1983) Science , vol.220 , pp. 568-575
    • Samuelsson, B.1
  • 43
    • 0035281741 scopus 로고    scopus 로고
    • RNA interference-2001
    • Sharp, P.A. (2001) RNA interference-2001. Genes Dev., 15, 485-490.
    • (2001) Genes Dev. , vol.15 , pp. 485-490
    • Sharp, P.A.1
  • 44
    • 0035846580 scopus 로고    scopus 로고
    • Intrinsic double-stranded-RNA processing activity of Escherichia coli ribonuclease III lacking the dsRNA-binding domain
    • Sun, W., Jun, E. and Nicholson, A.W. (2001) Intrinsic double-stranded-RNA processing activity of Escherichia coli ribonuclease III lacking the dsRNA-binding domain. Biochemistry, 40, 14976-14984.
    • (2001) Biochemistry , vol.40 , pp. 14976-14984
    • Sun, W.1    Jun, E.2    Nicholson, A.W.3
  • 45
    • 0035795428 scopus 로고    scopus 로고
    • RNA interference and small interfering RNAs
    • Tuschl, T. (2001) RNA interference and small interfering RNAs. Chembiochem., 2, 239-245.
    • (2001) Chembiochem. , vol.2 , pp. 239-245
    • Tuschl, T.1
  • 46
    • 0028295681 scopus 로고
    • 2.2 Mb of contiguous nucleotide sequence from chromosome III of C. elegans
    • Wilson, R. et al. (1994) 2.2 Mb of contiguous nucleotide sequence from chromosome III of C. elegans. Nature, 368, 32-38.
    • (1994) Nature , vol.368 , pp. 32-38
    • Wilson, R.1
  • 47
    • 0027504207 scopus 로고
    • 5-Lipoxygenase and 5-lipoxygenase-activating protein are localized in the nuclear envelope of activated human leukocytes
    • Woods, J.W., Evans, J.F., Ethier, D., Scott, S., Vickers, P.J., Hearn, L., Heibein, J.A., Charleson, S. and Singer, I.I. (1993) 5-Lipoxygenase and 5-lipoxygenase-activating protein are localized in the nuclear envelope of activated human leukocytes. J. Exp. Med., 178, 1935-1946.
    • (1993) J. Exp. Med. , vol.178 , pp. 1935-1946
    • Woods, J.W.1    Evans, J.F.2    Ethier, D.3    Scott, S.4    Vickers, P.J.5    Hearn, L.6    Heibein, J.A.7    Charleson, S.8    Singer, I.I.9
  • 48
    • 0028937635 scopus 로고
    • 5-Lipoxygenase is located in the euchromatin of the nucleus in resting human alveolar macrophages and translocates to the nuclear envelope upon cell activation
    • Woods, J.W., Coffey, M.J., Brock, T.G., Singer, I.I. and Peters-Golden, M. (1995) 5-Lipoxygenase is located in the euchromatin of the nucleus in resting human alveolar macrophages and translocates to the nuclear envelope upon cell activation. J. Clin. Invest., 95, 2035-2046.
    • (1995) J. Clin. Invest. , vol.95 , pp. 2035-2046
    • Woods, J.W.1    Coffey, M.J.2    Brock, T.G.3    Singer, I.I.4    Peters-Golden, M.5
  • 49
    • 0025164247 scopus 로고
    • A gene from S.pombe with homology to E.coli RNase III blocks conjugation and sporulation when overexpressed in wild type cells
    • Xu, H.P., Riggs, M., Rodgers, L. and Wigler, M. (1990) A gene from S.pombe with homology to E.coli RNase III blocks conjugation and sporulation when overexpressed in wild type cells. Nucleic Acids Res., 18, 5304.
    • (1990) Nucleic Acids Res. , vol.18 , pp. 5304
    • Xu, H.P.1    Riggs, M.2    Rodgers, L.3    Wigler, M.4
  • 50
    • 0034737298 scopus 로고    scopus 로고
    • RNAi: Double-stranded RNA directs the ATP-dependent cleavage of mRNA at 21 to 23 nucleotide intervals
    • Zamore, P.D., Tuschl, T., Sharp, P.A. and Bartel, D.P. (2000) RNAi: Double-stranded RNA directs the ATP-dependent cleavage of mRNA at 21 to 23 nucleotide intervals. Cell, 101, 25-33.
    • (2000) Cell , vol.101 , pp. 25-33
    • Zamore, P.D.1    Tuschl, T.2    Sharp, P.A.3    Bartel, D.P.4
  • 51
    • 0036845374 scopus 로고    scopus 로고
    • Human Dicer preferentially cleaves dsRNAs at their termini without a requirement for ATP
    • Zhang, H., Kolb, F.A., Brondani, V., Billy, E. and Filipowicz, W. (2002) Human Dicer preferentially cleaves dsRNAs at their termini without a requirement for ATP. EMBO J., 21, 5875-5885.
    • (2002) EMBO J. , vol.21 , pp. 5875-5885
    • Zhang, H.1    Kolb, F.A.2    Brondani, V.3    Billy, E.4    Filipowicz, W.5
  • 52
    • 0032857606 scopus 로고    scopus 로고
    • Pac1p, an RNase III homolog, is required for formation of the 3′ end of U2 snRNA in Schizosaccharomyces pombe
    • Zhou, D., Frendewey, D. and Lobo Ruppert, S.M. (1999) Pac1p, an RNase III homolog, is required for formation of the 3′ end of U2 snRNA in Schizosaccharomyces pombe. RNA, 5, 1083-1098.
    • (1999) RNA , vol.5 , pp. 1083-1098
    • Zhou, D.1    Frendewey, D.2    Lobo Ruppert, S.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.