Distinct roles for Drosophila Dicer-1 and Dicer-2 in the siRNA/miRNA silencing pathways

Cell

Volumn 117, Issue 1, 2004, Pages 69-81

  Lee, Young Sik ^a   Nakahara, Kenji ^a   Pham, John W ^a   Kim, Kevin ^a   He, Zhengying ^a   Sontheimer, Erik J ^a   Carthew, Richard W ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MICRORNA; SMALL INTERFERING RNA;

ARTICLE; COMPLEX FORMATION; DROSOPHILA; ENZYME ACTIVATION; GENE; GENE DICER1; GENE DICER2; GENE MUTATION; GENE SILENCING; MUTANT; NONHUMAN; PRECURSOR; PRIORITY JOURNAL; PROTEIN ASSEMBLY; RNA CLEAVAGE; RNA TRANSLATION;

ARACHNIDA; DROSOPHILA; HEXAPODA;

EID: 1842816517     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0092-8674(04)00261-2     Document Type: Article

References (45)

1. Abrahante J.E., Daul A.L., Li M., Volk M.L., Tennessen J.M., Miller E.A., Rougvie A.E. The Caenorhabditis elegans hunchback-like gene lin-57/hbl-1 controls developmental time and is regulated by microRNAs. Dev. Cell. 4:2003;625-637.
2. Berger J., Suzuki T., Senti K.A., Stubbs J., Schaffner G., Dickson B.J. Genetic mapping with SNP markers in Drosophila. Nat. Genet. 29:2001;475-481.
3. Bernstein E., Caudy A.A., Hammond S.M., Hannon G.J. Role for a bidentate ribonuclease in the initiation step of RNA interference. Nature. 409:2001;363-366.
4. Blaszczyk J., Tropea J.E., Bubunenko M., Routzahn K.M., Waugh D.S., Court D.L., Ji X. Crystallographic and modeling studies of RNase III suggest a mechanism for double-stranded RNA cleavage. Structure (Camb). 9:2001;1225-1236.
5. Brennecke J., Hipfner D.R., Stark A., Russell R.B., Cohen S.M. bantam encodes a developmentally regulated microRNA that controls cell proliferation and regulates the proapoptotic gene hid in Drosophila. Cell. 113:2003;25-36.
6. Chou T.B., Perrimon N. The autosomal FLP-DFS technique for generating germline mosaics in Drosophila melanogaster. Genetics. 144:1996;1673-1679.
7. Dasgupta S., Fernandez L., Kameyama L., Inada T., Nakamura Y., Pappas A., Court D.L. Genetic uncoupling of the dsRNA-binding and RNA cleavage activities of the Escherichia coli endoribonuclease RNase III-the effect of dsRNA binding on gene expression. Mol. Microbiol. 28:1998;629-640.
8. Doench J.G., Petersen C.P., Sharp P.A. siRNAs can function as miRNAs. Genes Dev. 17:2003;438-442.
9. Doi N., Zenno S., Ueda R., Ohki-Hamazaki H., Ui-Tei K., Saigo K. Short-interfering-RNA-mediated gene silencing in mammalian cells requires Dicer and eIF2C translation initiation factors. Curr. Biol. 13:2003;41-46.
10. Elbashir S.M., Lendeckel W., Tuschl T. RNA interference is mediated by 21- and 22-nucleotide RNAs. Genes Dev. 15:2001;188-200.
11. Grishok A., Pasquinelli A.E., Conte D., Li N., Parrish S., Ha I., Baillie D.L., Fire A., Ruvkun G., Mello C.C. Genes and mechanisms related to RNA interference regulate expression of the small temporal RNAs that control C. elegans developmental timing. Cell. 106:2001;23-34.
12. Hamilton A.J., Baulcombe D.C. A species of small antisense RNA in posttranscriptional gene silencing in plants. Science. 286:1999;950-952.
13. Hammond S.M., Bernstein E., Beach D., Hannon G.J. An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells. Nature. 404:2000;293-296.
14. Hammond S.M., Boettcher S., Caudy A.A., Kobayashi R., Hannon G.J. Argonaute2, a link between genetic and biochemical analyses of RNAi. Science. 293:2001;1146-1150.
15. Hannon G.J. RNA interference. Nature. 418:2002;244-251.
16. Hutvagner G., Zamore P.D. A MicroRNA in a Multiple-Turnover RNAi Enzyme Complex. Science. 297:2002;2056-2060.
17. Hutvagner G., McLachlan J., Pasquinelli A.E., Balint E., Tuschl T., Zamore P.D. A cellular function for the RNA-interference enzyme Dicer in the maturation of the let-7 small temporal RNA. Science. 293:2001;834-838.
18. Kennerdell J.R., Yamaguchi S., Carthew R.W. RNAi is activated during Drosophila oocyte maturation in a manner dependent on aubergine and spindle-E. Genes Dev. 16:2002;1884-1889.
19. Ketting R.F., Fischer S.E., Bernstein E., Sijen T., Hannon G.J., Plasterk R.H. Dicer functions in RNA interference and in synthesis of small RNA involved in developmental timing in C. elegans. Genes Dev. 15:2001;2654-2659.
20. Knight S.W., Bass B.L. A role for the RNase III enzyme DCR-1 in RNA interference and germ line development in Caenorhabditis elegans. Science. 293:2001;2269-2271.
21. Lai E.C. Micro RNAs are complementary to 3′ UTR sequence motifs that mediate negative post-transcriptional regulation. Nat. Genet. 30:2002;363-364.
22. Lai E.C., Posakony J.W. The Bearded box, a novel 3′ UTR sequence motif, mediates negative post- transcriptional regulation of Bearded and Enhancer of split Complex gene expression. Development. 124:1997;4847-4856.
23. Lai E.C., Burks C., Posakony J.W. The K box, a conserved 3′ UTR sequence motif, negatively regulates accumulation of enhancer of split complex transcripts. Development. 125:1998;4077-4088.
24. Lee T., Luo L. Mosaic analysis with a repressible cell marker for studies of gene function in neuronal morphogenesis. Neuron. 22:1999;451-461.
25. Lee Y.S., Carthew R.W. Making a better RNAi vector for Drosophila. Use of Intron Spacers Methods. 30:2003;322-329.
26. Lee R.C., Feinbaum R.L., Ambros V. The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14. Cell. 75:1993;843-854.
27. Lee Y., Jeon K., Lee J.T., Kim S., Kim V.N. MicroRNA maturation. stepwise processing and subcellular localization EMBO J. 21:2002;4663-4670.
28. Lee Y., Ahn C., Han J., Choi H., Kim J., Yim J., Lee J., Provost P., Radmark O., Kim S., Kim V.N. The nuclear RNase III Drosha initiates microRNA processing. Nature. 425:2003;415-419.
29. Lin S.Y., Johnson S.M., Abraham M., Vella M.C., Pasquinelli A., Gamberi C., Gottlieb E., Slack F.J. The C elegans hunchback homolog, hbl-1, controls temporal patterning and is a probable microRNA target. Dev. Cell. 4:2003;639-650.
30. Liu Q., Rand T.A., Kalidas S., Du F., Kim H.E., Smith D.P., Wang X. R2D2, a bridge between the initiation and effector steps of the Drosophila RNAi pathway. Science. 301:2003;1921-1925.
31. Llave C., Xie Z., Kasschau K.D., Carrington J.C. Cleavage of Scarecrow-like mRNA targets directed by a class of Arabidopsis miRNA. Science. 297:2002;2053-2056.
32. Myers J.W., Jones J.T., Meyer T., Ferrell J.E. Jr. Recombinant Dicer efficiently converts large dsRNAs into siRNAs suitable for gene silencing. Nat. Biotechnol. 21:2003;324-328.
33. Newsome T.P., Asling B., Dickson B.J. Analysis of Drosophila photoreceptor axon guidance in eye-specific mosaics. Development. 127:2000;851-860.
34. Nicholson A.W. The ribonuclease III superfamily. forms and functions in RNA maturation, decay, and gene silencing Hannon G.J. RNAi. A Guide to Gene Silencing:2003;149-174 Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
35. Nykänen A., Haley B., Zamore P.D. ATP requirements and small interfering RNA structure in the RNA interference pathway. Cell. 107:2001;309-321.
36. Palatnik J.F., Allen E., Wu X., Schommer C., Schwab R., Carrington J.C., Weigel D. Control of leaf morphogenesis by microRNAs. Nature. 425:2003;257-263.
37. Pham J.W., Pellino J.L., Lee Y.S., Carthew R.W., Sontheimer E.J. A Dicer-2-dependent 80S complex cleaves targeted mRNAs during RNAi in Drosophila. Cell. 117:2004;83-94., this issue.
38. Provost P., Dishart D., Doucet J., Frendewey D., Samuelsson B., Radmark O. Ribonuclease activity and RNA binding of recombinant human Dicer. EMBO J. 21:2002;5864-5874.
39. Reinhart B.J., Slack F.J., Basson M., Pasquinelli A.E., Bettinger J.C., Rougvie A.E., Horvitz H.R., Ruvkun G. The 21-nt let-7 RNA regulates developmental timing in C. elegans. Nature. 403:2000;901-906.
40. Stowers R.S., Schwarz T.L. A genetic method for generating Drosophila eyes composed exclusively of mitotic clones of a single genotype. Genetics. 152:1999;1631-1639.
41. Tabara H., Yigit E., Siomi H., Mello C.C. The dsRNA binding protein RDE-4 interacts with RDE-1, DCR-1, and a DExH-box helicase to direct RNAi in C. elegans. Cell. 109:2002;861-871.
42. Tang G., Reinhart B.J., Bartel D.P., Zamore P.D. A biochemical framework for RNA silencing in plants. Genes Dev. 17:2003;49-63.
43. Tuschl T., Zamore P.D., Lehmann R., Bartel D.P., Sharp P.A. Targeted mRNA degradation by double-stranded RNA in vitro. Genes Dev. 13:1999;3191-3197.
44. Xu C., Kauffmann R.C., Zhang J., Kladny S., Carthew R.W. Overlapping activators and repressors delimit transcriptional response to receptor tyrosine kinase signals in the Drosophila eye. Cell. 103:2000;87-97.
45. Zeng Y., Yi R., Cullen B.R. MicroRNAs and small interfering RNAs can inhibit mRNA expression by similar mechanisms. Proc. Natl. Acad. Sci. USA. 100:2003;9779-9784.