MicroRNA-dependent localization of targeted mRNAs to mammalian P-bodies

Nature Cell Biology

Volumn 7, Issue 7, 2005, Pages 719-723

  Liu, Jidong ^a   Valencia Sanchez, Marco Antonio ^b   Hannon, Gregory J ^a   Parker, Roy ^b  

^a Watson School of Biological Sciences   (United States)

^b UNIVERSITY OF ARIZONA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARGONAUTE PROTEIN; CYTOPLASM PROTEIN; MESSENGER RNA; MICRORNA; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL ORGANELLE; COMPLEX FORMATION; CONTROLLED STUDY; CYTOPLASM; EFFECTOR CELL; GENE SILENCING; HUMAN; HUMAN CELL; MAMMAL CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROCESSING BODY; PROTEIN LOCALIZATION; PROTEIN SYNTHESIS INHIBITION; RNA CLEAVAGE; RNA DEGRADATION; RNA INTERFERENCE; RNA PROCESSING; RNA TRANSLATION; TRANSLATION REGULATION;

3' UNTRANSLATED REGIONS; CAENORHABDITIS ELEGANS PROTEINS; CELL LINE; CELL LINE, TUMOR; CYTOPLASMIC STRUCTURES; ENDORIBONUCLEASES; GENE EXPRESSION REGULATION; HELA CELLS; HUMANS; IMMUNOPRECIPITATION; MICRORNAS; MICROSCOPY, FLUORESCENCE; MUTATION; PEPTIDE INITIATION FACTORS; PROTEIN BINDING; RECEPTORS, CXCR4; RNA TRANSPORT; RNA, MESSENGER; RNA, SMALL INTERFERING; RNA-INDUCED SILENCING COMPLEX; TRANS-ACTIVATORS; TRANSFECTION;

ANIMALIA; MAMMALIA;

EID: 22144478256     PISSN: 14657392     EISSN: None     Source Type: Journal    
DOI: 10.1038/ncb1274     Document Type: Article

References (30)

1. Hannon, G. J. RNA interference. Nature 418, 244-251 (2002).
2. Ingelfinger, D., Arndt-Jovin, D.J., Luhrmann, R. & Achsel, T. The human LSm1-7 proteins colocalize with the mRNA-degrading enzymes Dcp1/2 and Xrnl in distinct cytoplasmic foci. RNA 8, 1489-1501 (2002).
3. van Dijk, E. et al. Human Dcp2: a catalytically active mRNA decapping enzyme located in specific cytoplasmic structures. EMBO J. 21, 6915-6924 (2002).
4. Lykke-Andersen, J. Identification of a human decapping complex associated with hUpf proteins in nonsense-mediated decay. Mol. Cell. Biol. 22, 8114-8121 (2002).
5. Sheth, U. & Parker, R. Decapping and decay of messenger RNA occur in cytoplasmic processing bodies. Science 300, 805-808 (2003).
6. Teixeira, D., Sheth, U., Valencia-Sanchez, M.A., Brengues, M. & Parker, R. Processing bodies require RNA for assembly and contain nontranslating mRNAs. RNA 11, 371-382 (2005).
7. Cougot, N., Babajko, S. & Seraphin, B. Cytoplasmic foci are sites of mRNA decay in human cells. J. Cell. Biol. 165, 31-40 (2004).
8. Meister, G. & Tuschl, T. Mechanisms of gene silencing by double-stranded RNA. Nature 431, 343-349 (2004).
9. Wightman, B., Ha, I. & Ruvkun, G. Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegans. Cell 75, 855-862 (1993).
10. Lee, R. C., Feinbaum, R. L. & Ambros, V. The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14. Cell 75, 843-854 (1993).
11. Ketting, R. F. et al. Dicer functions in RNA interference and in synthesis of small RNA involved in developmental timing in C. elegans. Genes Dev. 15, 2654-2659 (2001).
12. Knight, S. W. & Bass, B. L. A role for the RNase III enzyme DCR-1 in RNA interference and germ line development in Caenorhabditis elegans. Science 293, 2269-2271 (2001).
13. Hutvagner, G. et al. A cellular function for the RNA-interference enzyme Dicer in the maturation of the let-7 small temporal RNA. Science 293, 834-838 (2001).
14. Bartel, D. P. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 116, 281-297 (2004).
15. Ambros, V. The functions of animal microRNAs. Nature 431, 350-355 (2004).
16. Liu, J. et al. Argonaute2 is the catalytic engine of mammalian RNAi. Science 305, 1437-1441 (2004).
17. Eystathioy, T. et al. The GW182 protein colocalizes with mRNA degradation associated proteins hDcp1 and hLSm4 in cytoplasmic GW bodies. RNA 9, 1171-1173 (2003).
18. Tharun, S. et al. Yeast Sm-like proteins function in mRNA decapping and decay. Nature 404, 515-518 (2000).
19. Ma, J. B., Ye, K. & Patel, D. J. Structural basis for overhang-specific small interfering RNA recognition by the PAZ domain. Nature 429, 318-322 (2004).
20. Janicki, S. M. et al. From silencing to gene expression: real-time analysis in single cells. Cell 116, 683-698 (2004).
21. Lewis, B. P., Shih, I. H., Jones-Rhoades, M. W., Bartel, D. P. & Burge, C. B. Prediction of mammalian microRNA targets. Cell 115, 787-798 (2003).
22. Doench, J. G., Petersen, C. P. & Sharp, P. A. siRNAs can function as miRNAs. Genes Dev. 17, 438-442 (2003).
23. Souret, F. F., Kastenmayer, J. P. & Green, P. J. AtXRN4 degrades mRNA in Arabidopsis and its substrates include selected miRNA targets. Mol. Cell 15, 173-183 (2004).
24. Orban, T. I. & Izaurralde, E. Decay of mRNAs targeted by RISC requires XRN1, the Ski complex, and the exosome. RNA 11, 459-469 (2005).
25. Newbury, S. & Woollard, A. The 5′-3′ exoribonuclease xrn-1 is essential for ventral epithelial enclosure during C. elegans embryogenesis. RNA 10, 59-65 (2004).
26. Gazzani, S., Lawrenson, T., Woodward, C., Headon, D. & Sablowski, R. A link between mRNA turnover and RNA interference in Arabidopsis. Science 306, 1046-1048 (2004).
27. Lim, L. P. et al. Microarray analysis shows that some microRNAS downregulate large numbers of target mRNAs. Nature 433, 769-773 (2005).
28. Jing, Q. et al. Involvement of microRNA in AU-rich element-mediated mRNA instability. Cell 120, 623-634 (2005).
29. Andrei, M. A. et al. A role for eIF4E and eIF4E-transporter in targeting mRNPs to mammalian processing bodies. RNA 11, 717-727 (2005).
30. Sen, G. L. & Blau, H. M. Argonaute 2/RISC resides in sites of mammalian mRNA decay known as cytoplasmic bodies. Nature Cell Biol. 7, 633-636 (2205).