Small RNAs with imperfect match to endogenous mRNA repress translation. Implications for off-target activity of small inhibitory RNA in mammalian cells

Journal of Biological Chemistry

Volumn 278, Issue 45, 2003, Pages 44312-44319

  Saxena, Sandeep ^a   Jónsson, Zophonías O ^b   Dutta, Anindya ^a  

^a UNIVERSITY OF VIRGINIA   (United States)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; DEGRADATION; GENES; TISSUE;

GENE EXPRESSION;

RNA;

COMPLEMENTARY RNA; MESSENGER RNA; RNA; SMALL INHIBITORY RNA; UNCLASSIFIED DRUG;

3' UNTRANSLATED REGION; 5' UNTRANSLATED REGION; ARTICLE; BASE MISPAIRING; CONTROLLED STUDY; GENE EXPRESSION; GENE REPRESSION; GENE SEQUENCE; GENE SILENCING; GENETIC CODE; HUMAN; HUMAN CELL; MAMMAL CELL; PRIORITY JOURNAL; PROTEIN TARGETING; RNA ANALYSIS; RNA DEGRADATION; RNA SEQUENCE; RNA TRANSLATION; TISSUE CULTURE CELL; TRANSLATION REGULATION;

3' UNTRANSLATED REGIONS; BASE PAIR MISMATCH; BASE PAIRING; BASE SEQUENCE; CELL LINE; GENE SILENCING; HELA CELLS; HUMANS; PHOSPHATES; PROTEIN BIOSYNTHESIS; RNA, ANTISENSE; RNA, MESSENGER; RNA, SMALL INTERFERING; RNA-INDUCED SILENCING COMPLEX; STRUCTURE-ACTIVITY RELATIONSHIP; TRANSFECTION;

MAMMALIA;

EID: 0142173075     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M307089200     Document Type: Article

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