메뉴 건너뛰기




Volumn 21, Issue 24, 2002, Pages 6915-6924

Human Dcp2: A catalytically active mRNA decapping enzyme located in specific cytoplasmic structures

Author keywords

Cap mRNA; Decay MutT Nudix nuclease turnover; MRNA

Indexed keywords

COMPLEMENTARY DNA; ENZYME; EXONUCLEASE; GUANOSINE DIPHOSPHATE; MESSENGER RNA; PROTEIN DCP1; PROTEIN DCP2; RECOMBINANT ENZYME; UNCLASSIFIED DRUG;

EID: 0037121926     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/cdf678     Document Type: Article
Times cited : (391)

References (37)
  • 2
    • 0031030491 scopus 로고    scopus 로고
    • A mouse cytoplasmic exoribonuclease (mXRN1p) with preference for G4 tetraplex substrates
    • Bashkirov, V.I., Scherthan, H., Solinger, J.A., Buerstedde, J.M. and Heyer, W.D. (1997) A mouse cytoplasmic exoribonuclease (mXRN1p) with preference for G4 tetraplex substrates. J. Cell Biol., 136, 761-773.
    • (1997) J. Cell Biol. , vol.136 , pp. 761-773
    • Bashkirov, V.I.1    Scherthan, H.2    Solinger, J.A.3    Buerstedde, J.M.4    Heyer, W.D.5
  • 4
    • 0029835350 scopus 로고    scopus 로고
    • The MutT proteins or 'Nudix' hydrolases, a family of versatile, widely distributed, 'housecleaning' enzymes
    • Bessman, M.J., Frick, D.N. and O'Handley, S.F. (1996) The MutT proteins or 'Nudix' hydrolases, a family of versatile, widely distributed, 'housecleaning' enzymes. J. Biol. Chem., 271, 25059-25062.
    • (1996) J. Biol. Chem. , vol.271 , pp. 25059-25062
    • Bessman, M.J.1    Frick, D.N.2    O'Handley, S.F.3
  • 5
    • 0034664803 scopus 로고    scopus 로고
    • Identification of a regulated pathway for nuclear pre-mRNA turnover
    • Bousquet-Antonelli, C., Presutti, C. and Tollervey, D. (2000) Identification of a regulated pathway for nuclear pre-mRNA turnover. Cell, 102, 765-775.
    • (2000) Cell , vol.102 , pp. 765-775
    • Bousquet-Antonelli, C.1    Presutti, C.2    Tollervey, D.3
  • 6
    • 0034599976 scopus 로고    scopus 로고
    • A Sm-like protein complex that participates in mRNA degradation
    • Bouveret, E., Rigaut, G., Shevchenko, A., Wilm, M. and Séraphin, B. (2000) A Sm-like protein complex that participates in mRNA degradation. EMBO J., 19, 1661-1671.
    • (2000) EMBO J. , vol.19 , pp. 1661-1671
    • Bouveret, E.1    Rigaut, G.2    Shevchenko, A.3    Wilm, M.4    Séraphin, B.5
  • 7
    • 0036781068 scopus 로고    scopus 로고
    • Ribosome components are associated with sites of transcription
    • Brogna, S., Sato, T.A. and Rosbash, M. (2002) Ribosome components are associated with sites of transcription. Mol. Cell, 10, 93-104.
    • (2002) Mol. Cell , vol.10 , pp. 93-104
    • Brogna, S.1    Sato, T.A.2    Rosbash, M.3
  • 8
    • 0035174662 scopus 로고    scopus 로고
    • A cis-acting element known to block 3′ mRNA degradation enhances expression of poly(A)-mRNA in wild-type yeast cells and phenocopies a ski mutant
    • Brown, J.T. and Johnson, A.W. (2001) A cis-acting element known to block 3′ mRNA degradation enhances expression of poly(A)-mRNA in wild-type yeast cells and phenocopies a ski mutant. RNA, 7, 1566-1577.
    • (2001) RNA , vol.7 , pp. 1566-1577
    • Brown, J.T.1    Johnson, A.W.2
  • 9
    • 0036469214 scopus 로고    scopus 로고
    • The yin and yang of the exosome
    • Butler, J.S. (2002) The yin and yang of the exosome. Trends Cell Biol., 12, 90-96.
    • (2002) Trends Cell Biol. , vol.12 , pp. 90-96
    • Butler, J.S.1
  • 10
    • 0029871812 scopus 로고    scopus 로고
    • Mechanisms and control of mRNA turnover in Saccharomyces cerevisiae
    • Caponigro, G. and Parker, R. (1996) Mechanisms and control of mRNA turnover in Saccharomyces cerevisiae. Microbiol. Rev., 60, 233-249.
    • (1996) Microbiol. Rev. , vol.60 , pp. 233-249
    • Caponigro, G.1    Parker, R.2
  • 11
    • 18044371822 scopus 로고    scopus 로고
    • AU binding proteins recruit the exosome to degrade ARE-containing mRNAs
    • Chen, C.Y. et al. (2001) AU binding proteins recruit the exosome to degrade ARE-containing mRNAs. Cell, 107, 451-464.
    • (2001) Cell , vol.107 , pp. 451-464
    • Chen, C.Y.1
  • 13
    • 0033180278 scopus 로고    scopus 로고
    • Should we kill the messenger? The role of the surveillance complex in translation termination and mRNA turnover
    • Czaplinski, K., Ruiz-Echevarria, M.J., Gonzalez, C.I. and Peltz, S.W. (1999) Should we kill the messenger? The role of the surveillance complex in translation termination and mRNA turnover. BioEssays, 21, 685-696.
    • (1999) BioEssays , vol.21 , pp. 685-696
    • Czaplinski, K.1    Ruiz-Echevarria, M.J.2    Gonzalez, C.I.3    Peltz, S.W.4
  • 14
    • 0035875115 scopus 로고    scopus 로고
    • The yeast POP2 gene encodes a nuclease involved in mRNA deadenylation
    • Daugeron, M.C., Mauxion, F. and Séraphin, B. (2001) The yeast POP2 gene encodes a nuclease involved in mRNA deadenylation. Nucleic Acids Res., 29, 2448-2455.
    • (2001) Nucleic Acids Res. , vol.29 , pp. 2448-2455
    • Daugeron, M.C.1    Mauxion, F.2    Séraphin, B.3
  • 15
    • 0033214061 scopus 로고    scopus 로고
    • The DCP2 protein is required for mRNA decapping in Saccharomyces cerevisiae and contains a functional MutT motif
    • Dunckley, T. and Parker, R. (1999) The DCP2 protein is required for mRNA decapping in Saccharomyces cerevisiae and contains a functional MutT motif. EMBO J., 18, 5411-5422.
    • (1999) EMBO J. , vol.18 , pp. 5411-5422
    • Dunckley, T.1    Parker, R.2
  • 16
    • 0036223709 scopus 로고    scopus 로고
    • A phosphorylated cytoplasmic autoantigen, GW182, Associates with a unique population of human mRNAs within novel cytoplasmic speckles
    • Eystathioy, T., Chan, E.K., Tenenbaum, S.A., Keene, J.D., Griffith, K. and Fritzler, M.J. (2002) A phosphorylated cytoplasmic autoantigen, GW182, Associates with a unique population of human mRNAs within novel cytoplasmic speckles. Mol. Biol. Cell, 13, 1338-1351.
    • (2002) Mol. Biol. Cell , vol.13 , pp. 1338-1351
    • Eystathioy, T.1    Chan, E.K.2    Tenenbaum, S.A.3    Keene, J.D.4    Griffith, K.5    Fritzler, M.J.6
  • 17
    • 0037013898 scopus 로고    scopus 로고
    • The DEAD box protein Dhh1 stimulates the decapping enzyme Dcpl
    • Fischer, N. and Weis, K. (2002) The DEAD box protein Dhh1 stimulates the decapping enzyme Dcpl. EMBO J., 21, 2788-2797.
    • (2002) EMBO J. , vol.21 , pp. 2788-2797
    • Fischer, N.1    Weis, K.2
  • 18
    • 0037155592 scopus 로고    scopus 로고
    • An mRNA surveillance mechanism that eliminates transcripts lacking termination codons
    • Frischmeyer, P.A., van Hoof, A., O'Donnell, K., Guerrerio, A.L., Parker, R. and Dietz, H.C. (2002) An mRNA surveillance mechanism that eliminates transcripts lacking termination codons. Science, 295, 2258-2261.
    • (2002) Science , vol.295 , pp. 2258-2261
    • Frischmeyer, P.A.1    Van Hoof, A.2    O'Donnell, K.3    Guerrerio, A.L.4    Parker, R.5    Dietz, H.C.6
  • 19
    • 0035282971 scopus 로고    scopus 로고
    • A novel mRNA-decapping activity in HeLa cytoplasmic extracts is regulated by AU-rich elements
    • Gao, M., Wilusz, C.J., Peltz, S.W. and Wilusz, J. (2001) A novel mRNA-decapping activity in HeLa cytoplasmic extracts is regulated by AU-rich elements. EMBO J., 20, 1134-1143.
    • (2001) EMBO J. , vol.20 , pp. 1134-1143
    • Gao, M.1    Wilusz, C.J.2    Peltz, S.W.3    Wilusz, J.4
  • 20
    • 0028948708 scopus 로고
    • Identification of a novel component of the nonsense-mediated mRNA decay pathway by use of an interacting protein screen
    • He, F. and Jacobson, A. (1995) Identification of a novel component of the nonsense-mediated mRNA decay pathway by use of an interacting protein screen. Genes Dev., 9, 437-454.
    • (1995) Genes Dev. , vol.9 , pp. 437-454
    • He, F.1    Jacobson, A.2
  • 21
    • 0027242173 scopus 로고
    • Stabilization and ribosome association of unspliced pre-mRNAs in a yeast upfl-mutant
    • He, F., Peltz, S.W., Donahue, J.L., Rosbash, M. and Jacobson, A. (1993) Stabilization and ribosome association of unspliced pre-mRNAs in a yeast upfl-mutant. Proc. Natl. Acad. Sci. USA, 90, 7034-7038.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 7034-7038
    • He, F.1    Peltz, S.W.2    Donahue, J.L.3    Rosbash, M.4    Jacobson, A.5
  • 22
    • 0028239360 scopus 로고
    • The mRNA (guanine-7-)methyltransferase domain of the vaccinia virus mRNA capping enzyme. Expression in Escherichia coli and structural and kinetic comparison to the intact capping enzyme
    • Higman, M.A., Christen, L.A. and Niles, E.G. (1994) The mRNA (guanine-7-)methyltransferase domain of the vaccinia virus mRNA capping enzyme. Expression in Escherichia coli and structural and kinetic comparison to the intact capping enzyme. J. Biol. Chem., 269, 14974-14981.
    • (1994) J. Biol. Chem. , vol.269 , pp. 14974-14981
    • Higman, M.A.1    Christen, L.A.2    Niles, E.G.3
  • 23
    • 0035839002 scopus 로고    scopus 로고
    • Coupled transcription and translation within nuclei of mammalian cells
    • Iborra, F.J., Jackson, D.A. and Cook, P.R. (2001) Coupled transcription and translation within nuclei of mammalian cells. Science, 293, 1139-1142.
    • (2001) Science , vol.293 , pp. 1139-1142
    • Iborra, F.J.1    Jackson, D.A.2    Cook, P.R.3
  • 24
    • 0035823036 scopus 로고    scopus 로고
    • Evidence for a pioneer round of mRNA translation: mRNAs subject to nonsense-mediated decay in mammalian cells are bound by CBP80 and CBP20
    • Ishigaki, Y., Li, X., Serin, G. and Maquat, L.E. (2001) Evidence for a pioneer round of mRNA translation: mRNAs subject to nonsense-mediated decay in mammalian cells are bound by CBP80 and CBP20. Cell, 106, 607-617.
    • (2001) Cell , vol.106 , pp. 607-617
    • Ishigaki, Y.1    Li, X.2    Serin, G.3    Maquat, L.E.4
  • 25
    • 0032473359 scopus 로고    scopus 로고
    • Isolation and characterization of Dcp1p, the yeast mRNA decapping enzyme
    • LaGrandeur, T.E. and Parker, R. (1998) Isolation and characterization of Dcp1p, the yeast mRNA decapping enzyme. EMBO J., 17, 1487-1496.
    • (1998) EMBO J. , vol.17 , pp. 1487-1496
    • LaGrandeur, T.E.1    Parker, R.2
  • 26
    • 0026782452 scopus 로고
    • Characterization of the XRN1 gene encoding a 5′→3′ exoribonuclease: Sequence data and analysis of disparate protein and mRNA levels of gene-disrupted yeast cells
    • Larimer, F.W., Hsu, C.L., Maupin, M.K. and Stevens, A. (1992) Characterization of the XRN1 gene encoding a 5′→3′ exoribonuclease: Sequence data and analysis of disparate protein and mRNA levels of gene-disrupted yeast cells. Gene, 120, 51-57.
    • (1992) Gene , vol.120 , pp. 51-57
    • Larimer, F.W.1    Hsu, C.L.2    Maupin, M.K.3    Stevens, A.4
  • 27
    • 0030005755 scopus 로고    scopus 로고
    • The I.M.A.G.E. Consortium: An integrated molecular analysis of genomes and their expression
    • Lennon, G., Auffray, C., Polymeropoulos, M. and Soares, M.B. (1996) The I.M.A.G.E. Consortium: An integrated molecular analysis of genomes and their expression. Genomics, 33, 151-152.
    • (1996) Genomics , vol.33 , pp. 151-152
    • Lennon, G.1    Auffray, C.2    Polymeropoulos, M.3    Soares, M.B.4
  • 28
    • 0030702085 scopus 로고    scopus 로고
    • The exosome: A conserved eukaryotic RNA processing complex containing multiple 3′→5′ exoribonucleases
    • Mitchell, P., Petfalski, E., Shevchenko, A., Mann, M. and Tollervey, D. (1997) The exosome: A conserved eukaryotic RNA processing complex containing multiple 3′→5′ exoribonucleases. Cell, 91, 457-466.
    • (1997) Cell , vol.91 , pp. 457-466
    • Mitchell, P.1    Petfalski, E.2    Shevchenko, A.3    Mann, M.4    Tollervey, D.5
  • 29
    • 0037080834 scopus 로고    scopus 로고
    • The mammalian exosome mediates the efficient degradation of mRNAs that contain AU-rich elements
    • Mukherjee, D., Gao, M., O'Connor, J.P., Raijmakers, R., Pruijn, G., Lutz, C.S. and Wilusz, J. (2002) The mammalian exosome mediates the efficient degradation of mRNAs that contain AU-rich elements. EMBO J., 21, 165-174.
    • (2002) EMBO J. , vol.21 , pp. 165-174
    • Mukherjee, D.1    Gao, M.2    O'Connor, J.P.3    Raijmakers, R.4    Pruijn, G.5    Lutz, C.S.6    Wilusz, J.7
  • 30
    • 0035937181 scopus 로고    scopus 로고
    • Orf135 from Escherichia coli is a Nudix hydrolase specific for CTP, dCTP, and 5-methyl-dCTP
    • O'Handley, S.F., Dunn, C.A. and Bessman, M.J. (2001) Orf135 from Escherichia coli is a Nudix hydrolase specific for CTP, dCTP, and 5-methyl-dCTP. J. Biol. Chem., 276, 5421-5426.
    • (2001) J. Biol. Chem. , vol.276 , pp. 5421-5426
    • O'Handley, S.F.1    Dunn, C.A.2    Bessman, M.J.3
  • 31
    • 0034732089 scopus 로고    scopus 로고
    • Yeast Sm-like proteins function in mRNA decapping and decay
    • Tharun, S., He, W., Mayes, A.E., Lennertz, P., Beggs, J.D. and Parker, R. (2000) Yeast Sm-like proteins function in mRNA decapping and decay. Nature, 404, 515-518.
    • (2000) Nature , vol.404 , pp. 515-518
    • Tharun, S.1    He, W.2    Mayes, A.E.3    Lennertz, P.4    Beggs, J.D.5    Parker, R.6
  • 32
    • 0035830508 scopus 로고    scopus 로고
    • The transcription factor associated Ccr4 and Caf1 proteins are components of the major cytoplasmic mRNA deadenylase in Saccharomyces cerevisiae
    • Tucker, M., Valencia-Sanchez, M.A., Staples, R.R., Chen, J., Denis, C.L. and Parker, R. (2001) The transcription factor associated Ccr4 and Caf1 proteins are components of the major cytoplasmic mRNA deadenylase in Saccharomyces cerevisiae. Cell, 104, 377-386.
    • (2001) Cell , vol.104 , pp. 377-386
    • Tucker, M.1    Valencia-Sanchez, M.A.2    Staples, R.R.3    Chen, J.4    Denis, C.L.5    Parker, R.6
  • 33
    • 0037117760 scopus 로고    scopus 로고
    • Messenger RNA degradation: Beginning at the end
    • van Hoof, A. and Parker, R. (2002) Messenger RNA degradation: Beginning at the end. Curr. Biol., 12, R285-R287.
    • (2002) Curr. Biol. , vol.12
    • Van Hoof, A.1    Parker, R.2
  • 34
    • 0037155584 scopus 로고    scopus 로고
    • Exosome-mediated recognition and degradation of mRNAs lacking a termination codon
    • van Hoof, A., Frischmeyer, P.A., Dietz, H.C. and Parker, R. (2002) Exosome-mediated recognition and degradation of mRNAs lacking a termination codon. Science, 295, 2262-2264.
    • (2002) Science , vol.295 , pp. 2262-2264
    • Van Hoof, A.1    Frischmeyer, P.A.2    Dietz, H.C.3    Parker, R.4
  • 35
    • 0034663782 scopus 로고    scopus 로고
    • The eukaryotic mRNA decapping protein Dcpl interacts physically and functionally with the eIF4F translation initiation complex
    • Vilela, C., Velasco, C., Ptushkina, M. and McCarthy, J.E. (2000) The eukaryotic mRNA decapping protein Dcpl interacts physically and functionally with the eIF4F translation initiation complex. EMBO J., 19, 4372-4382.
    • (2000) EMBO J. , vol.19 , pp. 4372-4382
    • Vilela, C.1    Velasco, C.2    Ptushkina, M.3    McCarthy, J.E.4
  • 36
    • 0035861864 scopus 로고    scopus 로고
    • Functional link between the mammalian exosome and mRNA decapping
    • Wang, Z. and Kiledjian, M. (2001) Functional link between the mammalian exosome and mRNA decapping. Cell, 107, 751-762.
    • (2001) Cell , vol.107 , pp. 751-762
    • Wang, Z.1    Kiledjian, M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.