Human RISC couples microRNA biogenesis and posttranscriptional gene silencing

Cell

Volumn 123, Issue 4, 2005, Pages 631-640

  Gregory, Richard I ^a   Chendrimada, Thimmaiah P ^a   Cooch, Neil ^a   Shiekhattar, Ramin ^a  

^a WISTAR INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; ARGONAUTE2; BINDING PROTEIN; DOUBLE STRANDED RNA; DOUBLE STRANDED RNA BINDING PROTEIN; MICRORNA; PROTEIN; RNA INDUCED SILENCING COMPLEX; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ARTICLE; BIOGENESIS; ENZYME SUBSTRATE; POSTTRANSCRIPTIONAL GENE SILENCING; PRIORITY JOURNAL; RNA CLEAVAGE; RNA PROCESSING;

EID: 27744537851     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cell.2005.10.022     Document Type: Article

References (52)

1. D.P. Bartel MicroRNAs: genomics, biogenesis, mechanism, and function Cell 116 2004 281 297
2. E. Bernstein, A.A. Caudy, S.M. Hammond, and G.J. Hannon Role for a bidentate ribonuclease in the initiation step of RNA interference Nature 409 2001 363 366
3. A.A. Caudy, M. Myers, G.J. Hannon, and S.M. Hammond Fragile X-related protein and VIG associate with the RNA interference machinery Genes Dev. 16 2001 2491 2496
4. T.P. Chendrimada, R.I. Gregory, E. Kumaraswamy, J. Norman, N. Cooch, K. Nishikura, and R. Shiekhattar TRBP recruits the Dicer complex to Ago2 for microRNA processing and gene silencing Nature 436 2005 740 744 10.1038/nature03868 Published online June 22, 2005
5. A.M. Denli, B.B. Tops, R.H. Plasterk, R.F. Ketting, and G.J. Hannon Processing of primary microRNAs by the Microprocessor complex Nature 432 2004 231 235
6. N. Doi, S. Zenno, R. Ueda, H. Ohki-Hamazaki, K. Ui-Tei, and K. Saigo Short-interfering-RNA-mediated gene silencing in mammalian cells requires Dicer and eIF2C translation initiation factors Curr. Biol. 13 2003 41 46
7. S.M. Elbashir, J. Harborth, W. Lendeckel, A. Yalcin, K. Weber, and T. Tuschl Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells Nature 411 2001 494 498
8. W. Filipowicz RNAi: the nuts and bolts of the RISC machine Cell 122 2005 17 20
9. A. Fire, S. Xu, M.K. Montgomery, S.A. Kostas, S.E. Driver, and C.C. Mello Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans Nature 391 1998 806 811
10. K. Forstemann, Y. Tomari, T. Du, V.V. Vagin, A.M. Denli, D.P. Bratu, C. Klattenhoff, W.E. Theurkauf, and P.D. Zamore Normal microRNA maturation and germ-line stem cell maintenance requires Loquacious, a double-stranded RNA-binding domain protein PLoS Biol. 3 2005 e236 10.1371/journal.pbio.0030236
11. R.I. Gregory, K.P. Yan, G. Amuthan, T. Chendrimada, B. Doratotaj, N. Cooch, and R. Shiekhattar The Microprocessor complex mediates the genesis of microRNAs Nature 432 2004 235 240
12. A. Grishok, H. Tabara, and C.C. Mello Genetic requirements for inheritance of RNAi in C. elegans Science 287 2000 2494 2497
13. A. Grishok, A.E. Pasquinelli, D. Conte, N. Li, S. Parrish, I. Ha, D.L. Baillie, A. Fire, G. Ruvkun, and C.C. Mello Genes and mechanisms related to RNA interference regulate expression of the small temporal RNAs that control C. elegans developmental timing Cell 106 2001 23 34
14. B. Haley, and P.D. Zamore Kinetic analysis of the RNAi enzyme complex Nat. Struct. Mol. Biol. 11 2004 599 606
15. S.M. Hammond, E. Bernstein, D. Beach, and G.J. Hannon An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells Nature 404 2000 293 296
16. S.M. Hammond, S. Boettcher, A.A. Caudy, R. Kobayashi, and G.J. Hannon Argonaute2, a link between genetic and biochemical analyses of RNAi Science 293 2001 1146 1150
17. J. Han, Y. Lee, K.H. Yeom, Y.K. Kim, H. Jin, and V.N. Kim The Drosha-DGCR8 complex in primary microRNA processing Genes Dev. 18 2004 3016 3027
18. G. Hutvagner, and P.D. Zamore A microRNA in a multiple-turnover RNAi enzyme complex Science 297 2002 2056 2060
19. G. Hutvagner, J. McLachlan, A.E. Pasquinelli, E. Balint, T. Tuschl, and P.D. Zamore A cellular function for the RNA-interference enzyme Dicer in the maturation of the let-7 small temporal RNA Science 293 2001 834 838
20. F. Jiang, X. Ye, X. Liu, L. Fincher, D. McKearin, and Q. Liu Dicer-1 and R3D1-L catalyze microRNA maturation in Drosophila Genes Dev. 19 2005 1674 1679
21. R.F. Ketting, S.E. Fischer, E. Bernstein, T. Sijen, G.J. Hannon, and R.H. Plasterk Dicer functions in RNA interference and in synthesis of small RNA involved in developmental timing in C. elegans Genes Dev. 15 2001 2654 2659
22. A. Khvorova, A. Reynolds, and S.D. Jayasena Functional siRNAs and miRNAs exhibit strand bias Cell 115 2003 209 216
23. D.H. Kim, M.A. Behlke, S.D. Rose, M.S. Chang, S. Choi, and J.J. Rossi Synthetic dsRNA Dicer substrates enhance RNAi potency and efficacy Nat. Biotechnol. 23 2005 222 226
24. V.N. Kim MicroRNA biogenesis: coordinated cropping and dicing Nat. Rev. Mol. Cell Biol. 6 2005 376 385
25. Y.S. Lee, K. Nakahara, J.W. Pham, K. Kim, Z. He, E.J. Sontheimer, and R.W. Carthew Distinct roles for Drosophila Dicer-1 and Dicer-2 in the siRNA/miRNA silencing pathways Cell 117 2004 69 81
26. L.P. Lim, N.C. Lau, P. Garrett-Engele, A. Grimson, J.M. Schelter, J. Castle, D.P. Bartel, P.S. Linsley, and J.M. Johnson Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs Nature 433 2005 769 773
27. A. Lingel, B. Simon, E. Izaurralde, and M. Sattler Structure and nucleic-acid binding of the Drosophila Argonaute 2 PAZ domain Nature 426 2003 465 469
28. J. Liu, M.A. Carmell, F.V. Rivas, C.G. Marsden, J.M. Thomson, J.J. Song, S.M. Hammond, L. Joshua-Tor, and G.J. Hannon Argonaute2 is the catalytic engine of mammalian RNAi Science 305 2004 1437 1441
29. Q. Liu, T.A. Rand, S. Kalidas, F. Du, H.E. Kim, D.P. Smith, and X. Wang R2D2, a bridge between the initiation and effector steps of the Drosophila RNAi pathway Science 301 2003 1921 1925
30. J.B. Ma, K. Ye, and D.J. Patel Structural basis for overhang-specific small interfering RNA recognition by the PAZ domain Nature 429 2004 318 322
31. J.B. Ma, Y.R. Yuan, G. Meister, Y. Pei, T. Tuschl, and D.J. Patel Structural basis for 5′-end-specific recognition of guide RNA by the A. fulgidus Piwi protein Nature 434 2005 666 670
32. J. Martinez, A. Patkaniowska, H. Urlaub, R. Luhrmann, and T. Tuschl Single-stranded antisense siRNAs guide target RNA cleavage in RNAi Cell 110 2002 563 574
33. G. Meister, M. Landthaler, A. Patkaniowska, Y. Dorsett, G. Teng, and T. Tuschl Human Argonaute2 mediates RNA cleavage targeted by miRNAs and siRNAs Mol. Cell 15 2004 185 197
34. Z. Mourelatos, J. Dostie, S. Paushkin, A. Sharma, B. Charroux, L. Abel, J. Rappsilber, M. Mann, and G. Dreyfuss miRNPs: a novel class of ribonucleoproteins containing numerous microRNAs Genes Dev. 16 2000 720 728
35. C.D. Novina, and P.A. Sharp The RNAi revolution Nature 430 2004 161 164
36. A. Nykanen, B. Haley, and P.D. Zamore ATP requirements and small interfering RNA structure in the RNA interference pathway Cell 107 2001 309 321
37. K. Okamura, A. Ishizuka, H. Siomi, and M.C. Siomi Distinct roles for Argonaute proteins in small RNA-directed RNA cleavage pathways Genes Dev. 18 2004 1655 1666
38. J.W. Pham, J.L. Pellino, Y.S. Lee, R.W. Carthew, and E.J. Sontheimer A Dicer-2-dependent 80s complex cleaves targeted mRNAs during RNAi in Drosophila Cell 117 2004 83 94
39. P. Provost, D. Dishart, J. Doucet, D. Frendewey, B. Samuelsson, and O. Radmark Ribonuclease activity and RNA binding of recombinant human Dicer EMBO J. 21 2002 5864 5874
40. F.V. Rivas, N.H. Tolia, J.J. Song, J.P. Aragon, J. Liu, G.J. Hannon, and L. Joshua-Tor Purified Argonaute2 and an siRNA form recombinant human RISC Nat. Struct. Mol. Biol. 12 2005 340 349
41. K. Saito, A. Ishizuka, H. Siomi, and M.C. Siomi Processing of pre-microRNAs by the Dicer-1-Loquacious complex in Drosophila cells PLoS Biol. 3 2005 e235 10.1371/journal.pbio.0030235
42. D.S. Schwarz, G. Hutvagner, T. Du, Z. Xu, N. Aronin, and P.D. Zamore Asymmetry in the assembly of the RNAi enzyme complex Cell 115 2003 199 208
43. D. Siolas, C. Lerner, J. Burchard, W. Ge, P.S. Linsley, P.J. Paddison, G.J. Hannon, and M.A. Cleary Synthetic shRNAs as potent RNAi triggers Nat. Biotechnol. 23 2005 227 231
44. J.J. Song, J. Liu, N.H. Tolia, J. Schneiderman, S.K. Smith, R.A. Martienssen, G.J. Hannon, and L. Joshua-Tor The crystal structure of the Argonaute2 PAZ domain reveals an RNA binding motif in RNAi effector complexes Nat. Struct. Biol. 10 2003 1026 1032
45. J.J. Song, S.K. Smith, G.J. Hannon, and L. Joshua-Tor Crystal structure of Argonaute and its implications for RISC slicer activity Science 305 2004 1434 1437
46. E.J. Sontheimer Assembly and function of RNA silencing complexes Nat. Rev. Mol. Cell Biol. 6 2005 127 138
47. H. Tabara, E. Yigit, H. Siomi, and C.C. Mello The dsRNA binding protein RDE-4 interacts with RDE-1, DCR-1, and a DExH-box helicase to direct RNAi in C. elegans Cell 109 2002 861 871
48. N. Tahbaz, F.A. Kolb, H. Zhang, K. Jaronczyk, W. Filipowicz, and T.C. Hobman Characterization of the interactions between mammalian PAZ PIWI domain proteins and Dicer EMBO Rep. 5 2004 189 194
49. Y. Tomari, C. Matranga, B. Haley, N. Martinez, and P.D. Zamore A protein sensor for siRNA asymmetry Science 306 2004 1377 1380
50. K.S. Yan, S. Yan, A. Farooq, A. Han, L. Zeng, and M.M. Zhou Structure and conserved RNA binding of the PAZ domain Nature 426 2004 468 474
51. H. Zhang, F.A. Kolb, V. Brondani, E. Billy, and W. Filipowicz Human Dicer preferentially cleaves dsRNAs at their termini without a requirement for ATP EMBO J. 21 2002 5875 5885
52. H. Zhang, F.A. Kolb, L. Jaskiewicz, E. Westhof, and W. Filipowicz Single processing center models for human Dicer and bacterial RNase III Cell 118 2004 57 68