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Volumn 26, Issue 31, 2007, Pages 4550-4562

Tumor suppressor Pdcd4 inhibits invasion/intravasation and regulates urokinase receptor (u-PAR) gene expression via Sp-transcription factors

Author keywords

Intravasation; Invasion; Pdcd4; Sp1; Sp3; u PAR

Indexed keywords

CHLORAMPHENICOL ACETYLTRANSFERASE; MESSENGER RNA; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR SP; TRANSCRIPTION FACTOR SP1; TRANSCRIPTION FACTOR SP3; TUMOR SUPPRESSOR PROTEIN; UROKINASE RECEPTOR;

EID: 34447270490     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/sj.onc.1210234     Document Type: Article
Times cited : (151)

References (61)
  • 1
    • 0035172910 scopus 로고    scopus 로고
    • Urokinase receptor and fibronectin regulate the ERKMAPK to p38MAPK activity ratios that determine carcinoma cell proliferation or dormancy in vivo
    • Aguirre-Ghiso J, Liu D, Mignatti A, Kovalski K, Ossowski L. (2001). Urokinase receptor and fibronectin regulate the ERKMAPK to p38MAPK activity ratios that determine carcinoma cell proliferation or dormancy in vivo. Mol Biol Cell 12: 863-879.
    • (2001) Mol Biol Cell , vol.12 , pp. 863-879
    • Aguirre-Ghiso, J.1    Liu, D.2    Mignatti, A.3    Kovalski, K.4    Ossowski, L.5
  • 2
    • 0037379794 scopus 로고    scopus 로고
    • ERKMAPK activity as a determinant of tumor growth and dormancy; regulation by p38SAPK
    • Aguirre-Ghiso J, Estrada Y, Liu D, Ossowski L. (2003). ERKMAPK activity as a determinant of tumor growth and dormancy; regulation by p38SAPK. Cancer Res 63: 1684-1695.
    • (2003) Cancer Res , vol.63 , pp. 1684-1695
    • Aguirre-Ghiso, J.1    Estrada, Y.2    Liu, D.3    Ossowski, L.4
  • 3
    • 0042121063 scopus 로고    scopus 로고
    • Downregulation of urokinase plasminogen activator receptor expression inhibits Erk signalling with concomitant suppression of invasiveness due to loss of uPAR-b1 integrin complex in colon cancer cells
    • Ahmed N, Oliva K, Wang Y, Quinn M, Rice G. (2003). Downregulation of urokinase plasminogen activator receptor expression inhibits Erk signalling with concomitant suppression of invasiveness due to loss of uPAR-b1 integrin complex in colon cancer cells. Br J Cancer 89: 374-384.
    • (2003) Br J Cancer , vol.89 , pp. 374-384
    • Ahmed, N.1    Oliva, K.2    Wang, Y.3    Quinn, M.4    Rice, G.5
  • 5
    • 0033603453 scopus 로고    scopus 로고
    • Transcriptional induction of the urokinase receptor gene by a constitutively active Src. Requirement of an upstream motif (-152/-135) bound with Sp1
    • Allgayer H, Wang H, Gallick GE, Crabtree A, Mazar A, Jones T et al. (1999a). Transcriptional induction of the urokinase receptor gene by a constitutively active Src. Requirement of an upstream motif (-152/-135) bound with Sp1. J Biol Chem 274: 18428-18437.
    • (1999) J Biol Chem , vol.274 , pp. 18428-18437
    • Allgayer, H.1    Wang, H.2    Gallick, G.E.3    Crabtree, A.4    Mazar, A.5    Jones, T.6
  • 6
    • 0032778698 scopus 로고    scopus 로고
    • Targeted disruption of the K-ras oncogene in an invasive colon cancer cell line down-regulates urokinase receptor expression and plasminogen-dependent proteolysis
    • Allgayer H, Wang H, Shirasawa S, Sasazuki T, Boyd D. (1999b). Targeted disruption of the K-ras oncogene in an invasive colon cancer cell line down-regulates urokinase receptor expression and plasminogen-dependent proteolysis. Br J Cancer 80: 1884-1891.
    • (1999) Br J Cancer , vol.80 , pp. 1884-1891
    • Allgayer, H.1    Wang, H.2    Shirasawa, S.3    Sasazuki, T.4    Boyd, D.5
  • 7
    • 0033582506 scopus 로고    scopus 로고
    • Transactivation of the urokinase-type plasminogen activator receptor gene through a novel promoter motif bound with an activator protein-2alpha- related factor
    • Allgayer H, Wang H, Wang Y, Heiss MM, Bauer R, Nyormoi O et al. (1999c). Transactivation of the urokinase-type plasminogen activator receptor gene through a novel promoter motif bound with an activator protein-2alpha- related factor. J Biol Chem 274: 4702-4714.
    • (1999) J Biol Chem , vol.274 , pp. 4702-4714
    • Allgayer, H.1    Wang, H.2    Wang, Y.3    Heiss, M.M.4    Bauer, R.5    Nyormoi, O.6
  • 8
    • 0032193771 scopus 로고    scopus 로고
    • Differential transcriptional regulation of CD161 and a novel gene, 197/15a, by IL-2, IL-15, and IL-12 in NK and T Cells
    • Azzoni L, Zatsepina O, Abebe B, Bennett IM, Kanakaraj P, Perussia B. (1998). Differential transcriptional regulation of CD161 and a novel gene, 197/15a, by IL-2, IL-15, and IL-12 in NK and T Cells. J Immunol 161: 243-253.
    • (1998) J Immunol , vol.161 , pp. 243-253
    • Azzoni, L.1    Zatsepina, O.2    Abebe, B.3    Bennett, I.M.4    Kanakaraj, P.5    Perussia, B.6
  • 9
    • 6344231276 scopus 로고    scopus 로고
    • Transformation suppressor protein Pdcd4 interferes with JNK-mediated phosphorylation of c-Jun and recruitment of the coactivator p300 by c-Jun
    • Bitomsky N, Bohm M, Klempnauer KH. (2004). Transformation suppressor protein Pdcd4 interferes with JNK-mediated phosphorylation of c-Jun and recruitment of the coactivator p300 by c-Jun. Oncogene 23: 7484-7493.
    • (2004) Oncogene , vol.23 , pp. 7484-7493
    • Bitomsky, N.1    Bohm, M.2    Klempnauer, K.H.3
  • 10
    • 0027550662 scopus 로고
    • Urokinase and urokinase receptor: A paracrine/autocrine system regulating cell migration and invasiveness
    • Blasi F. (1993). Urokinase and urokinase receptor: a paracrine/autocrine system regulating cell migration and invasiveness. BioEssays 15: 105-111.
    • (1993) BioEssays , vol.15 , pp. 105-111
    • Blasi, F.1
  • 11
    • 0024580569 scopus 로고
    • Determination of the effects of epidermal growth factor on urokinase secretion and urokinase receptor display in a well-differentiated human colon carcinoma cell line
    • Boyd D, Brattain M. (1989). Determination of the effects of epidermal growth factor on urokinase secretion and urokinase receptor display in a well-differentiated human colon carcinoma cell line. Cancer Res 49: 1948-1953.
    • (1989) Cancer Res , vol.49 , pp. 1948-1953
    • Boyd, D.1    Brattain, M.2
  • 12
    • 0023818612 scopus 로고
    • Determination of the levels of urokinase and its receptor in human colon carcinoma cell lines
    • Boyd D, Florent G, Kim P, Brattain M. (1988). Determination of the levels of urokinase and its receptor in human colon carcinoma cell lines. Cancer Res 48: 3112-3116.
    • (1988) Cancer Res , vol.48 , pp. 3112-3116
    • Boyd, D.1    Florent, G.2    Kim, P.3    Brattain, M.4
  • 13
    • 0042524204 scopus 로고    scopus 로고
    • Loss of PDCD4 expression in human lung cancer correlates with tumour progression and prognosis
    • Chen Y, Knosel T, Kristiansen G, Pietas A, Garber ME, Matsuhashi S et al. (2003). Loss of PDCD4 expression in human lung cancer correlates with tumour progression and prognosis. Pathology 200: 640-646.
    • (2003) Pathology , vol.200 , pp. 640-646
    • Chen, Y.1    Knosel, T.2    Kristiansen, G.3    Pietas, A.4    Garber, M.E.5    Matsuhashi, S.6
  • 14
    • 0033598712 scopus 로고    scopus 로고
    • Differentially expressed protein Pdcd4 inhibits tumor promoter-induced neoplastic transformation
    • Cmarik J, Min H, Hegamyer G, Zhan S, Kulesz-Martin M, Yoshinaga H et al. (1999). Differentially expressed protein Pdcd4 inhibits tumor promoter-induced neoplastic transformation. Proc Natl Acad Sci USA 96: 14037-14042.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 14037-14042
    • Cmarik, J.1    Min, H.2    Hegamyer, G.3    Zhan, S.4    Kulesz-Martin, M.5    Yoshinaga, H.6
  • 15
    • 0029078962 scopus 로고
    • Shc binding to nerve growth factor receptor is mediated by the phosphotyrosine interaction domain
    • Dikic I, Batzer A, Blaikie P, Obermeier A, Ullrich A, Schlessinger J et al. (1995). Shc binding to nerve growth factor receptor is mediated by the phosphotyrosine interaction domain. J Biol Chem 270: 15125-15129.
    • (1995) J Biol Chem , vol.270 , pp. 15125-15129
    • Dikic, I.1    Batzer, A.2    Blaikie, P.3    Obermeier, A.4    Ullrich, A.5    Schlessinger, J.6
  • 16
    • 0023140631 scopus 로고
    • Do proteases play a role in cancer invasion and metastasis?
    • Duffy M. (1987). Do proteases play a role in cancer invasion and metastasis? Eur J Cancer Clin Oncol 23: 583-589.
    • (1987) Eur J Cancer Clin Oncol , vol.23 , pp. 583-589
    • Duffy, M.1
  • 17
    • 0037532985 scopus 로고    scopus 로고
    • Transcriptional regulation of the urokinase receptor (u-PAR)-a central molecule of invasion and metastasis
    • Fuchs T, Allgayer H. (2003). Transcriptional regulation of the urokinase receptor (u-PAR)-a central molecule of invasion and metastasis. Biol Chem 384: 755-761.
    • (2003) Biol Chem , vol.384 , pp. 755-761
    • Fuchs, T.1    Allgayer, H.2
  • 18
    • 0026922126 scopus 로고
    • The biology of colorectal carcinoma
    • Ozols RF, Steele G, Kinsella TJ eds, Mosby Year Book Inc: St Louis, pp
    • Gallick G, Jessup J. (1992). The biology of colorectal carcinoma. In: Ozols RF, Steele G, Kinsella TJ (eds). Current Problems in Cancer. Mosby Year Book Inc: St Louis, pp 261-328.
    • (1992) Current Problems in Cancer , pp. 261-328
    • Gallick, G.1    Jessup, J.2
  • 20
    • 2342501442 scopus 로고    scopus 로고
    • Programmed cell death protein 4 (PDCD4) acts as a tumor suppressor in neuroendocrine tumor cells
    • Göke R, Gregel C, Göke A, Arnold R, Schmidt H, Lankat-Buttgereit B. (2004). Programmed cell death protein 4 (PDCD4) acts as a tumor suppressor in neuroendocrine tumor cells. Ann NY Acad Sci 1014: 220-222.
    • (2004) Ann NY Acad Sci , vol.1014 , pp. 220-222
    • Göke, R.1    Gregel, C.2    Göke, A.3    Arnold, R.4    Schmidt, H.5    Lankat-Buttgereit, B.6
  • 21
    • 0035015311 scopus 로고    scopus 로고
    • beta(3)A-integrin downregulates the urokinasetype plasminogen activator receptor (u-PAR) through a PEA3/ets transcriptional silencing element in the u-PAR promoter
    • Hapke S, Gawaz M, Dehne K, Kohler J, Marshall JF, Graeff H et al. (2001). beta(3)A-integrin downregulates the urokinasetype plasminogen activator receptor (u-PAR) through a PEA3/ets transcriptional silencing element in the u-PAR promoter. Mol Cell Biol 21: 2118-2132.
    • (2001) Mol Cell Biol , vol.21 , pp. 2118-2132
    • Hapke, S.1    Gawaz, M.2    Dehne, K.3    Kohler, J.4    Marshall, J.F.5    Graeff, H.6
  • 22
    • 0028885643 scopus 로고
    • Individual development and uPA-receptor expression of disseminated tumour cells in bone marrow: A reference to early systemic disease in solid cancer
    • Heiss MM, Allgayer H, Gruetzner KU, Funke I, Babic R, Jauch KW et al. (1995). Individual development and uPA-receptor expression of disseminated tumour cells in bone marrow: a reference to early systemic disease in solid cancer. Nat Med 1: 1035-1039.
    • (1995) Nat Med , vol.1 , pp. 1035-1039
    • Heiss, M.M.1    Allgayer, H.2    Gruetzner, K.U.3    Funke, I.4    Babic, R.5    Jauch, K.W.6
  • 23
    • 0029925798 scopus 로고    scopus 로고
    • The prognostic impact of the urokinase-type plasminogen activator system is associated with tumour differentiation in gastric cancer
    • Heiss MM, Babic R, Allgayer H, Gruetzner KU, Jauch KW, Loehrs U et al. (1996). The prognostic impact of the urokinase-type plasminogen activator system is associated with tumour differentiation in gastric cancer. Eur J Surg Oncol 22: 74-77.
    • (1996) Eur J Surg Oncol , vol.22 , pp. 74-77
    • Heiss, M.M.1    Babic, R.2    Allgayer, H.3    Gruetzner, K.U.4    Jauch, K.W.5    Loehrs, U.6
  • 24
    • 0027082979 scopus 로고
    • Urokinase (uPA) and its inhibitor PAI-1 are strong and independent prognostic factors in node-negative breast cancer
    • Janicke F, Schmitt M, Pache L, Ulm K, Harbeck N, Hofler H et al. (1993). Urokinase (uPA) and its inhibitor PAI-1 are strong and independent prognostic factors in node-negative breast cancer. Breast Cancer Res Treat 24: 195-208.
    • (1993) Breast Cancer Res Treat , vol.24 , pp. 195-208
    • Janicke, F.1    Schmitt, M.2    Pache, L.3    Ulm, K.4    Harbeck, N.5    Hofler, H.6
  • 25
    • 22244491639 scopus 로고    scopus 로고
    • Epidermal expression of the translation inhibitor programmed cell death 4 suppresses tumorigenesis
    • Jansen AP, Camalier C, Colburn NH. (2005). Epidermal expression of the translation inhibitor programmed cell death 4 suppresses tumorigenesis. Cancer Res 65: 6034-6041.
    • (2005) Cancer Res , vol.65 , pp. 6034-6041
    • Jansen, A.P.1    Camalier, C.2    Colburn, N.H.3
  • 26
    • 4444285717 scopus 로고    scopus 로고
    • Characterization of programmed cell death 4 in multiple human cancers reveals a novel enhancer of drug sensitivity
    • Jansen AP, Camalier CE, Stark C, Colburn NH. (2004). Characterization of programmed cell death 4 in multiple human cancers reveals a novel enhancer of drug sensitivity. Mol Cancer Ther 3: 103-110.
    • (2004) Mol Cancer Ther , vol.3 , pp. 103-110
    • Jansen, A.P.1    Camalier, C.E.2    Stark, C.3    Colburn, N.H.4
  • 28
    • 0032493871 scopus 로고    scopus 로고
    • Requirement for specific proteases in cancer cell intravasation as revealed by a novel semiquantitative PCR-based assay
    • Kim J, Yu W, Kovalski K, Ossowski L. (1998). Requirement for specific proteases in cancer cell intravasation as revealed by a novel semiquantitative PCR-based assay. Cell 94: 353-362.
    • (1998) Cell , vol.94 , pp. 353-362
    • Kim, J.1    Yu, W.2    Kovalski, K.3    Ossowski, L.4
  • 30
    • 0029809873 scopus 로고    scopus 로고
    • Requirement of an upstream AP-1 motif for the constitutive and phorbol ester-inducible expression of the urokinase-type plasminogen activator receptor gene
    • Lengyel E, Wang H, Stepp E, Juarez J, Wang Y, Doe W et al. (1996). Requirement of an upstream AP-1 motif for the constitutive and phorbol ester-inducible expression of the urokinase-type plasminogen activator receptor gene. J Biol Chem 271: 23176-23184.
    • (1996) J Biol Chem , vol.271 , pp. 23176-23184
    • Lengyel, E.1    Wang, H.2    Stepp, E.3    Juarez, J.4    Wang, Y.5    Doe, W.6
  • 32
    • 0035408087 scopus 로고    scopus 로고
    • Interference with the urokinase plasminogen activator system: A promising therapy concept for solid tumours
    • Muehlenweg B, Sperl S, Magdolen V, Schmitt M, Harbeck N. (2001). Interference with the urokinase plasminogen activator system: a promising therapy concept for solid tumours. Expert Opin Biol Ther 1: 683-691.
    • (2001) Expert Opin Biol Ther , vol.1 , pp. 683-691
    • Muehlenweg, B.1    Sperl, S.2    Magdolen, V.3    Schmitt, M.4    Harbeck, N.5
  • 33
    • 0028321634 scopus 로고
    • Prognostic impact of urokinase-type plasminogen activator and its inhibitor PAI-1 in completely resected gastric cancer
    • Nekarda H, Schmitt M, Ulm K, Wenninger A, Vogelsang H, Becker K et al. (1994). Prognostic impact of urokinase-type plasminogen activator and its inhibitor PAI-1 in completely resected gastric cancer. Cancer Res 54: 2900-2907.
    • (1994) Cancer Res , vol.54 , pp. 2900-2907
    • Nekarda, H.1    Schmitt, M.2    Ulm, K.3    Wenninger, A.4    Vogelsang, H.5    Becker, K.6
  • 34
    • 0030296790 scopus 로고    scopus 로고
    • Molecular cloning of the genes suppressed in RVC lymphoma cells by topoisomerase inhibitors
    • Onishi Y, Kizaki H. (1996). Molecular cloning of the genes suppressed in RVC lymphoma cells by topoisomerase inhibitors. Biochem Biophys Res Commun 228: 7-13.
    • (1996) Biochem Biophys Res Commun , vol.228 , pp. 7-13
    • Onishi, Y.1    Kizaki, H.2
  • 35
    • 0032581496 scopus 로고    scopus 로고
    • Cloning of the TIS gene suppressed by topoisomerase inhibitors
    • Onishi Y, Hashimoto S, Kizaki H. (1998). Cloning of the TIS gene suppressed by topoisomerase inhibitors. Gene 215: 453-459.
    • (1998) Gene , vol.215 , pp. 453-459
    • Onishi, Y.1    Hashimoto, S.2    Kizaki, H.3
  • 36
    • 0026341460 scopus 로고
    • In vivo paracrine interaction between urokinase and its receptor: Effect on tumor cell invasion
    • Ossowski L, Clunie G, Masucci MT, Blasi F. (1991). In vivo paracrine interaction between urokinase and its receptor: effect on tumor cell invasion. J Cell Biol 115: 1107-1112.
    • (1991) J Cell Biol , vol.115 , pp. 1107-1112
    • Ossowski, L.1    Clunie, G.2    Masucci, M.T.3    Blasi, F.4
  • 37
    • 0024238269 scopus 로고
    • In vivo invasion of modified chorioallantoic membrane by tumor cells: The role of cell surface-bound urokinase
    • Ossowski L. (1988). In vivo invasion of modified chorioallantoic membrane by tumor cells: the role of cell surface-bound urokinase. J Cell Biol 107: 2437-2445.
    • (1988) J Cell Biol , vol.107 , pp. 2437-2445
    • Ossowski, L.1
  • 39
    • 0032857460 scopus 로고    scopus 로고
    • The transcription factors Sp1, Sp3, and AP-2 are required for constitutive matrix metalloproteinase-2 gene expression in astroglioma cells
    • Qin H, Sun Y, Benveniste EN. (1999). The transcription factors Sp1, Sp3, and AP-2 are required for constitutive matrix metalloproteinase-2 gene expression in astroglioma cells. J Biol Chem 274: 29130-29137.
    • (1999) J Biol Chem , vol.274 , pp. 29130-29137
    • Qin, H.1    Sun, Y.2    Benveniste, E.N.3
  • 40
    • 0033969298 scopus 로고    scopus 로고
    • Transcription of the human c-Src promoter is dependent on Sp1, a novel pyrimidine binding factor SPy, and can be inhibited by triplex-forming oligonucleotides
    • Ritchie S, Boyd F, Wong J, Bonham K. (2000). Transcription of the human c-Src promoter is dependent on Sp1, a novel pyrimidine binding factor SPy, and can be inhibited by triplex-forming oligonucleotides. J Biol Chem 275: 847-854.
    • (2000) J Biol Chem , vol.275 , pp. 847-854
    • Ritchie, S.1    Boyd, F.2    Wong, J.3    Bonham, K.4
  • 41
    • 29344473741 scopus 로고    scopus 로고
    • Combination Analysis of Activator Protein-1 Family Members, Sp1 and an Activator Protein-2A-Related Factor Binding to Different Regions of the Urokinase Receptor Gene in Resected Colorectal Cancers
    • Schewe D, Biller T, Maurer G, Asangani IA, Leupold JH, Lengyel E et al. (2005). Combination Analysis of Activator Protein-1 Family Members, Sp1 and an Activator Protein-2A-Related Factor Binding to Different Regions of the Urokinase Receptor Gene in Resected Colorectal Cancers. Clin Cancer Res 11: 8538-8548.
    • (2005) Clin Cancer Res , vol.11 , pp. 8538-8548
    • Schewe, D.1    Biller, T.2    Maurer, G.3    Asangani, I.A.4    Leupold, J.H.5    Lengyel, E.6
  • 43
    • 0031027464 scopus 로고    scopus 로고
    • Post transcriptional regulation of urokinase receptor mRNA: Identification of a novel urokinase receptor mRNA binding protein in human mesothelioma cells
    • Shetty S, Kumar A, Idell S. (1997). Post transcriptional regulation of urokinase receptor mRNA: identification of a novel urokinase receptor mRNA binding protein in human mesothelioma cells. Mol Cell Biol 17: 1075-1083.
    • (1997) Mol Cell Biol , vol.17 , pp. 1075-1083
    • Shetty, S.1    Kumar, A.2    Idell, S.3
  • 44
    • 3042709446 scopus 로고    scopus 로고
    • Post transcriptional regulation of urokinase receptor mRNA: Identification of a novel urokinase receptor mRNA binding protein in human mesothelioma cells
    • Shetty S, Muniyappa H, Halady PKS, Idell S. (2004). Post transcriptional regulation of urokinase receptor mRNA: identification of a novel urokinase receptor mRNA binding protein in human mesothelioma cells. Am J Respir Cell Mol Biol 31: 100-106.
    • (2004) Am J Respir Cell Mol Biol , vol.31 , pp. 100-106
    • Shetty, S.1    Muniyappa, H.2    Halady, P.K.S.3    Idell, S.4
  • 45
    • 0029595270 scopus 로고
    • Isolation of a novel mouse gene MA-3 that is induced upon programmed cell death
    • Shibahara K, Asano M, Ishida Y, Aoki T, Koike T, Honjo T. (1995). Isolation of a novel mouse gene MA-3 that is induced upon programmed cell death. Gene 166: 297-301.
    • (1995) Gene , vol.166 , pp. 297-301
    • Shibahara, K.1    Asano, M.2    Ishida, Y.3    Aoki, T.4    Koike, T.5    Honjo, T.6
  • 46
    • 0033399923 scopus 로고    scopus 로고
    • Assignment of the programmed cell death 4 gene (PDCD4) to human chromosome band 10q24 by in situ hybridization
    • Soejima H, Miyoshi O, Yoshinaga H, Masaki Z, Ozaki I, Kajiwara S et al. (1999). Assignment of the programmed cell death 4 gene (PDCD4) to human chromosome band 10q24 by in situ hybridization. Cytogenet Cell Genet 87: 113-114.
    • (1999) Cytogenet Cell Genet , vol.87 , pp. 113-114
    • Soejima, H.1    Miyoshi, O.2    Yoshinaga, H.3    Masaki, Z.4    Ozaki, I.5    Kajiwara, S.6
  • 47
    • 0034804331 scopus 로고    scopus 로고
    • Differentially expressed cDNAs in PLCbeta3-induced tumor suppression in a human endocrine pancreatic tumor cell line: Activation of the human mismatch repair protein 3 gene
    • Stalberg P, Lopez-Egido JR, Wang S, Gobl A, Oberg K, Skogseid B. (2001). Differentially expressed cDNAs in PLCbeta3-induced tumor suppression in a human endocrine pancreatic tumor cell line: activation of the human mismatch repair protein 3 gene. Biochem Biophys Res Commun 281: 227-231.
    • (2001) Biochem Biophys Res Commun , vol.281 , pp. 227-231
    • Stalberg, P.1    Lopez-Egido, J.R.2    Wang, S.3    Gobl, A.4    Oberg, K.5    Skogseid, B.6
  • 48
    • 0033591451 scopus 로고    scopus 로고
    • An N-terminal region of Sp1 targets its proteasome-dependent degradation in vitro
    • Su K, Roos M, Yang X, Han I, Paterson AJ, Kudlow JE. (1999). An N-terminal region of Sp1 targets its proteasome-dependent degradation in vitro. J Biol Chem 274: 15194-15202.
    • (1999) J Biol Chem , vol.274 , pp. 15194-15202
    • Su, K.1    Roos, M.2    Yang, X.3    Han, I.4    Paterson, A.J.5    Kudlow, J.E.6
  • 49
    • 0029058918 scopus 로고
    • Modulation of urokinase and urokinase receptor gene expression in human renal cell carcinoma
    • Wagner S, Atkinson M, Thanner S, Wagner C, Schmitt M, Wilhelm O et al. (1995). Modulation of urokinase and urokinase receptor gene expression in human renal cell carcinoma. Am J Pathol 147: 183-192.
    • (1995) Am J Pathol , vol.147 , pp. 183-192
    • Wagner, S.1    Atkinson, M.2    Thanner, S.3    Wagner, C.4    Schmitt, M.5    Wilhelm, O.6
  • 50
    • 0028067512 scopus 로고
    • Transcriptional activation of the urokinase receptor gene in invasive colon cancer
    • Wang H, Skibber J, Juarez J, Boyd D. (1994). Transcriptional activation of the urokinase receptor gene in invasive colon cancer. Int J Cancer 58: 650-657.
    • (1994) Int J Cancer , vol.58 , pp. 650-657
    • Wang, H.1    Skibber, J.2    Juarez, J.3    Boyd, D.4
  • 51
    • 0034118807 scopus 로고    scopus 로고
    • Identification of a novel nuclear factor-kappaB sequence involved in expression of urokinase-type plasminogen activator receptor
    • Wang Y, Dang J, Wang H, Allgayer H, Murrell GA, Boyd D. (2000). Identification of a novel nuclear factor-kappaB sequence involved in expression of urokinase-type plasminogen activator receptor. Eur J Biochem 267: 3248-3254.
    • (2000) Eur J Biochem , vol.267 , pp. 3248-3254
    • Wang, Y.1    Dang, J.2    Wang, H.3    Allgayer, H.4    Murrell, G.A.5    Boyd, D.6
  • 52
    • 1942453838 scopus 로고    scopus 로고
    • A Novel function of the MA-3 domains in transformation and translation suppressor Pdcd4 is essential for its binding to eukaryotic translation initiation factor 4A
    • Yang H, Cho M, Zakowicz H, Hegamyer G, Sonenberg N, Colburn NH. (2004). A Novel function of the MA-3 domains in transformation and translation suppressor Pdcd4 is essential for its binding to eukaryotic translation initiation factor 4A. Mol Cell Bio 24: 3894-3906.
    • (2004) Mol Cell Bio , vol.24 , pp. 3894-3906
    • Yang, H.1    Cho, M.2    Zakowicz, H.3    Hegamyer, G.4    Sonenberg, N.5    Colburn, N.H.6
  • 53
    • 0037216626 scopus 로고    scopus 로고
    • The transformation suppressor Pdcd4 is a novel eukaryotic translation initiation factor 4A binding protein that inhibits translation
    • Yang H, Jansen A, Komar AA, Zheng X, Merrick WC, Costes S et al. (2003a). The transformation suppressor Pdcd4 is a novel eukaryotic translation initiation factor 4A binding protein that inhibits translation. Mol Cell Biol 23: 26-37.
    • (2003) Mol Cell Biol , vol.23 , pp. 26-37
    • Yang, H.1    Jansen, A.2    Komar, A.A.3    Zheng, X.4    Merrick, W.C.5    Costes, S.6
  • 54
    • 0035825611 scopus 로고    scopus 로고
    • A novel transformation suppressor, Pdcd4, inhibits AP-1 transactivation but not NF-kB or ODC transactivation
    • Yang H, Jansen A, Nair R, Shibahara K, Verma AK, Cmarik JL et al. (2001a). A novel transformation suppressor, Pdcd4, inhibits AP-1 transactivation but not NF-kB or ODC transactivation. Oncogene 20: 669-676.
    • (2001) Oncogene , vol.20 , pp. 669-676
    • Yang, H.1    Jansen, A.2    Nair, R.3    Shibahara, K.4    Verma, A.K.5    Cmarik, J.L.6
  • 55
    • 0038209450 scopus 로고    scopus 로고
    • Pdcd4 suppresses tumor phenotype in JB6 cells by inhibiting AP-1 transactivation
    • Yang H, Knies J, Stark C, Colburn NH. (2003b). Pdcd4 suppresses tumor phenotype in JB6 cells by inhibiting AP-1 transactivation. Oncogene 22: 3712-3720.
    • (2003) Oncogene , vol.22 , pp. 3712-3720
    • Yang, H.1    Knies, J.2    Stark, C.3    Colburn, N.H.4
  • 56
    • 32044459728 scopus 로고    scopus 로고
    • Tumorigenesis suppressor Pdcd4 down-regulates MAP4K1 expression to suppress colon carcinoma cell invasion
    • Yang H, Matthews C, Clair T, Wang Q, Baker AR, Li CCH et al. (2006). Tumorigenesis suppressor Pdcd4 down-regulates MAP4K1 expression to suppress colon carcinoma cell invasion. Mol Cell Biol 26: 1297-1306.
    • (2006) Mol Cell Biol , vol.26 , pp. 1297-1306
    • Yang, H.1    Matthews, C.2    Clair, T.3    Wang, Q.4    Baker, A.R.5    Li, C.C.H.6
  • 57
    • 0035811072 scopus 로고    scopus 로고
    • O-linkage of N-acetylglucosamine to Sp1 activation domain inhibits its transcriptional capability
    • Yang X, Su K, Roos MD, Chang Q, Paterson AJ, Kudlow JE. (2001b). O-linkage of N-acetylglucosamine to Sp1 activation domain inhibits its transcriptional capability. Proc Natl Acad Sci USA 98: 6611-6616.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 6611-6616
    • Yang, X.1    Su, K.2    Roos, M.D.3    Chang, Q.4    Paterson, A.J.5    Kudlow, J.E.6
  • 58
    • 0033498486 scopus 로고    scopus 로고
    • Novel human PDCD4 (H731) gene expressed in proliferative cells is expressed in the small duct epithelial cells of the breast as revealed by an anti-H731 antibody
    • Yoshinaga H, Matsuhashi S, Fujiyama C, Masaki Z. (1999). Novel human PDCD4 (H731) gene expressed in proliferative cells is expressed in the small duct epithelial cells of the breast as revealed by an anti-H731 antibody. Pathol Int 49: 1067-1077.
    • (1999) Pathol Int , vol.49 , pp. 1067-1077
    • Yoshinaga, H.1    Matsuhashi, S.2    Fujiyama, C.3    Masaki, Z.4
  • 59
    • 13944274057 scopus 로고    scopus 로고
    • Mutational analysis of the DEAD-box RNA helicase eIF4AII characterizes its interaction with transformation suppressor Pdcd4 and eIF4GI
    • Zakowicz H, Yang H, Stark C, Wlodawer A, Laronde-Leblanc N, Colburn NH. (2005). Mutational analysis of the DEAD-box RNA helicase eIF4AII characterizes its interaction with transformation suppressor Pdcd4 and eIF4GI. RNA 11: 261-274.
    • (2005) RNA , vol.11 , pp. 261-274
    • Zakowicz, H.1    Yang, H.2    Stark, C.3    Wlodawer, A.4    Laronde-Leblanc, N.5    Colburn, N.H.6
  • 60
    • 0035958553 scopus 로고    scopus 로고
    • Detection of differentially expressed genes in human colon carcinoma cells treated with a selective COX-2 inhibitor
    • Zhang Z, DuBois R. (2001). Detection of differentially expressed genes in human colon carcinoma cells treated with a selective COX-2 inhibitor. Oncogene 20: 4450-4456.
    • (2001) Oncogene , vol.20 , pp. 4450-4456
    • Zhang, Z.1    DuBois, R.2
  • 61
    • 0036894603 scopus 로고    scopus 로고
    • A quantitative analysis of rate-limiting steps in the metastatic cascade using humanspecific real-time polymerase chain reaction
    • Zijlstra A, Mellor R, Panzarella G, Aimes RT, Hooper JD, Marchenko ND et al. (2002). A quantitative analysis of rate-limiting steps in the metastatic cascade using humanspecific real-time polymerase chain reaction. Cancer Res 62: 7083-7092.
    • (2002) Cancer Res , vol.62 , pp. 7083-7092
    • Zijlstra, A.1    Mellor, R.2    Panzarella, G.3    Aimes, R.T.4    Hooper, J.D.5    Marchenko, N.D.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.