Frequent deregulations in the hedgehog signaling network and cross-talks with the epidermal growth factor receptor pathway involved in cancer progression and targeted therapies

Pharmacological Reviews

Volumn 62, Issue 3, 2010, Pages 497-524

  Mimeault, Murielle ^a   Batra, Surinder K ^a  

^a UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 (2 DIFLUOROMETHYLBENZIMIDAZOL 1 YL) 4,6 DIMORPHOLINO 1,3,5 TRIAZINE; 3 BENZYL 7 CYANO 2,3,4,5 TETRAHYDRO 1 (1H IMIDAZOL 4 YLMETHYL) 4 (2 THIENYLSULFONYL) 1H 1,4 BENZODIAZEPINE; 4 (3 CHLOROANILINO) 6,7 DIMETHOXYQUINAZOLINE; 4 [4 (1,3 BENZODIOXOL 5 YL) 5 (2 PYRIDINYL) 1H IMIDAZOL 2 YL]BENZAMIDE; 4 [4 (4' CHLORO 2 BIPHENYLYLMETHYL) 1 PIPERAZINYL] N [4 [3 DIMETHYLAMINO 1 (PHENYLTHIOMETHYL)PROPYLAMINO] 3 NITROBENZENESULFONYL]BENZAMIDE; 5 AZA 2' DEOXYCYTIDINE; ANTINEOPLASTIC AGENT; AZACITIDINE; BETA CATENIN; CETUXIMAB; CHIR 265; CYCLOPAMINE; DOCETAXEL; EPIDERMAL GROWTH FACTOR RECEPTOR; ERLOTINIB; GDC 0449; GEFITINIB; GEMCITABINE; IPI 926; MONOCLONAL ANTIBODY DC101; PELITINIB; RAPAMYCIN; SALAZOSULFAPYRIDINE; SALINOSPORAMIDE A; SONIC HEDGEHOG PROTEIN; SORAFENIB; TEMSIROLIMUS; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA RECEPTOR; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ABSENCE OF SIDE EFFECTS; ADVANCED CANCER; BASAL CELL CARCINOMA; BONE MARROW; CANCER GROWTH; CANCER PATIENT; CANCER RELAPSE; CANCER SURVIVAL; CLINICAL TRIAL; DRUG MEGADOSE; EUKARYOTIC FLAGELLUM; GENE TARGETING; HUMAN; METASTASIS; MORPHOGENESIS; NEUROPROTECTION; NONHUMAN; ONCOGENE; ORGANOGENESIS; POSTNATAL DEVELOPMENT; PRIORITY JOURNAL; PROSTATE CANCER; PROTEIN EXPRESSION; PROTEIN STRUCTURE; REGULATORY MECHANISM; REVIEW; SIGNAL TRANSDUCTION; STEM CELL; TISSUE REGENERATION;

CELL TRANSFORMATION, NEOPLASTIC; DISEASE PROGRESSION; HEDGEHOG PROTEINS; HUMANS; NEOPLASMS; NEOPLASTIC STEM CELLS; RECEPTOR, EPIDERMAL GROWTH FACTOR; SIGNAL TRANSDUCTION;

EID: 77956269175     PISSN: 00316997     EISSN: 15210081     Source Type: Journal    
DOI: 10.1124/pr.109.002329     Document Type: Review

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