-
1
-
-
4544285754
-
Suppression of the Shh pathway using a small molecule inhibitor eliminates medulloblastoma in Ptc1(+/-)p53(-/-) mice
-
Romer JT, Kimura H, Magdaleno S, Sasai K, Fuller C, Baines H, Connelly M, Stewart CF, Gould S, Rubin LL, et al. (2004). Suppression of the Shh pathway using a small molecule inhibitor eliminates medulloblastoma in Ptc1(+/-)p53(-/-) mice. Cancer Cell 6, 229-240.
-
(2004)
Cancer Cell
, vol.6
, pp. 229-240
-
-
Romer, J.T.1
Kimura, H.2
Magdaleno, S.3
Sasai, K.4
Fuller, C.5
Baines, H.6
Connelly, M.7
Stewart, C.F.8
Gould, S.9
Rubin, L.L.10
-
2
-
-
34548170996
-
The sonic hedgehog signaling network in development and neoplasia
-
Chari NS and McDonnell TJ (2007). The sonic hedgehog signaling network in development and neoplasia. Adv Anat Pathol 14, 344-352.
-
(2007)
Adv Anat Pathol
, vol.14
, pp. 344-352
-
-
Chari, N.S.1
McDonnell, T.J.2
-
3
-
-
34248573807
-
Medulloblastomas derived from Cxcr6 mutant mice respond to treatment with a smoothened inhibitor
-
Sasai K, Romer JT, Kimura H, Eberhart DE, Rice DS, and Curran T (2007). Medulloblastomas derived from Cxcr6 mutant mice respond to treatment with a smoothened inhibitor. Cancer Res 67, 3871-3877.
-
(2007)
Cancer Res
, vol.67
, pp. 3871-3877
-
-
Sasai, K.1
Romer, J.T.2
Kimura, H.3
Eberhart, D.E.4
Rice, D.S.5
Curran, T.6
-
4
-
-
1942473030
-
Induction of the differentiation and apoptosis of tumor cells in vivo with efficiency and selectivity
-
Tabs S and Avci O (2004). Induction of the differentiation and apoptosis of tumor cells in vivo with efficiency and selectivity. Eur J Dermatol 14, 96-102.
-
(2004)
Eur J Dermatol
, vol.14
, pp. 96-102
-
-
Tabs, S.1
Avci, O.2
-
5
-
-
31544458968
-
Cytotoxic effects induced by a combination of cyclopamine and gefitinib, the selective hedgehog and epidermal growth factor receptor signaling inhibitors, in prostate cancer cells
-
Mimeault M, Moore E, Moniaux N, Henichart JP, Depreux P, Lin MF, and Batra SK (2006). Cytotoxic effects induced by a combination of cyclopamine and gefitinib, the selective hedgehog and epidermal growth factor receptor signaling inhibitors, in prostate cancer cells. Int J Cancer 118, 1022-1031.
-
(2006)
Int J Cancer
, vol.118
, pp. 1022-1031
-
-
Mimeault, M.1
Moore, E.2
Moniaux, N.3
Henichart, J.P.4
Depreux, P.5
Lin, M.F.6
Batra, S.K.7
-
6
-
-
35348837163
-
Cyclopamine-mediated hedgehog pathway inhibition depletes stem-like cancer cells in glioblastoma
-
Bar EE, Chaudhry A, Lin A, Fan X, Schreck K, Matsui W, Piccirillo S, Vescovi AL, DiMeco F, Olivi A, et al. (2007). Cyclopamine-mediated hedgehog pathway inhibition depletes stem-like cancer cells in glioblastoma. Stem Cells 25, 2524-2533.
-
(2007)
Stem Cells
, vol.25
, pp. 2524-2533
-
-
Bar, E.E.1
Chaudhry, A.2
Lin, A.3
Fan, X.4
Schreck, K.5
Matsui, W.6
Piccirillo, S.7
Vescovi, A.L.8
DiMeco, F.9
Olivi, A.10
-
7
-
-
0037200078
-
Medulloblastoma growth inhibition by hedgehog pathway blockade
-
Berman DM, Karhadkar SS, Hallahan AR, Pritchard JI, Eberhart CG, Watkins DN, Chen JK, Cooper MK, Taipale J, Olson JM, et al. (2002). Medulloblastoma growth inhibition by hedgehog pathway blockade. Science 297, 1559-1561.
-
(2002)
Science
, vol.297
, pp. 1559-1561
-
-
Berman, D.M.1
Karhadkar, S.S.2
Hallahan, A.R.3
Pritchard, J.I.4
Eberhart, C.G.5
Watkins, D.N.6
Chen, J.K.7
Cooper, M.K.8
Taipale, J.9
Olson, J.M.10
-
8
-
-
33644775686
-
Targeting multidrug resistance in cancer
-
Szakacs G, Paterson JK, Ludwig JA, Booth-Genthe C, and Gottesman MM (2006). Targeting multidrug resistance in cancer. Nat Rev Drug Discov 5, 219-234.
-
(2006)
Nat Rev Drug Discov
, vol.5
, pp. 219-234
-
-
Szakacs, G.1
Paterson, J.K.2
Ludwig, J.A.3
Booth-Genthe, C.4
Gottesman, M.M.5
-
10
-
-
0034795256
-
The ABC transporter Bcrp1/ABCG2 is expressed in a wide variety of stem cells and is a molecular determinant of the side-population phenotype
-
Zhou S, Schuetz JD, Bunting KD, Colapietro AM, Sampath J, Morris JJ, Lagutina I, Grosveld GC, Osawa M, Nakauchi H, et al. (2001). The ABC transporter Bcrp1/ABCG2 is expressed in a wide variety of stem cells and is a molecular determinant of the side-population phenotype. Nat Med 7, 1028-1034.
-
(2001)
Nat Med
, vol.7
, pp. 1028-1034
-
-
Zhou, S.1
Schuetz, J.D.2
Bunting, K.D.3
Colapietro, A.M.4
Sampath, J.5
Morris, J.J.6
Lagutina, I.7
Grosveld, G.C.8
Osawa, M.9
Nakauchi, H.10
-
11
-
-
34648821257
-
Molecular heterogeneity of breast carcinomas and the cancer stem cell hypothesis
-
Stingl J and Caldas C (2007). Molecular heterogeneity of breast carcinomas and the cancer stem cell hypothesis. Nat Rev Cancer 7, 791-799.
-
(2007)
Nat Rev Cancer
, vol.7
, pp. 791-799
-
-
Stingl, J.1
Caldas, C.2
-
12
-
-
38449091379
-
Markers in normal and cancer stem cells
-
Natarajan TG and FitzGerald KT (2007). Markers in normal and cancer stem cells. Cancer Biomark 3, 211-231.
-
(2007)
Cancer Biomark
, vol.3
, pp. 211-231
-
-
Natarajan, T.G.1
FitzGerald, K.T.2
-
13
-
-
33847296106
-
Targeted therapy for cancer stem cells: The patched pathway and ABC transporters
-
Lou H and Dean M (2007). Targeted therapy for cancer stem cells: the patched pathway and ABC transporters. Oncogene 26, 1357-1360.
-
(2007)
Oncogene
, vol.26
, pp. 1357-1360
-
-
Lou, H.1
Dean, M.2
-
14
-
-
34249878632
-
Sonic Hedgehog promotes multiple drug resistance by regulation of drug transport
-
Sims-Mourtada J, Izzo JG, Ajani J, and Chao KS (2007). Sonic Hedgehog promotes multiple drug resistance by regulation of drug transport. Oncogene 26, 5674-5679.
-
(2007)
Oncogene
, vol.26
, pp. 5674-5679
-
-
Sims-Mourtada, J.1
Izzo, J.G.2
Ajani, J.3
Chao, K.S.4
-
15
-
-
35148846396
-
ABCG2/BCRP expression modulates D-luciferin based bioluminescence imaging
-
Zhang Y, Bressler JP, Neal J, Lal B, Bhang H-E, Laterra J, and Pomper MG (2007). ABCG2/BCRP expression modulates D-luciferin based bioluminescence imaging. Cancer Res 67, 9389-9397.
-
(2007)
Cancer Res
, vol.67
, pp. 9389-9397
-
-
Zhang, Y.1
Bressler, J.P.2
Neal, J.3
Lal, B.4
Bhang, H.-E.5
Laterra, J.6
Pomper, M.G.7
-
16
-
-
1242338786
-
Imaging tri-fusion multimodality reporter gene expression in living subjects
-
Ray P, De A, Min JJ, Tsien RY, and Gambhir SS (2004). Imaging tri-fusion multimodality reporter gene expression in living subjects. Cancer Res 64, 1323-1330.
-
(2004)
Cancer Res
, vol.64
, pp. 1323-1330
-
-
Ray, P.1
De, A.2
Min, J.J.3
Tsien, R.Y.4
Gambhir, S.S.5
-
17
-
-
0033922511
-
Inhibitory effect of the reversal agents V-104, GF120918 and Pluronic L61 on MDR1 Pgp-, MRP1- and MRP2-mediated transport
-
Evers R, Kool M, Smith AJ, van Deemter L, de Haas M, and Borst P (2000). Inhibitory effect of the reversal agents V-104, GF120918 and Pluronic L61 on MDR1 Pgp-, MRP1- and MRP2-mediated transport. Br J Cancer 83, 366-374.
-
(2000)
Br J Cancer
, vol.83
, pp. 366-374
-
-
Evers, R.1
Kool, M.2
Smith, A.J.3
van Deemter, L.4
de Haas, M.5
Borst, P.6
-
18
-
-
0347382812
-
Mutations at amino acid 482 in the ABCG2 gene affect substrate and antagonist specificity
-
Robey RW, Honjo Y, Morisaki K, Nadjem TA, Runge S, Risbood M, Poruchynsky MS, and Bates SE (2003). Mutations at amino acid 482 in the ABCG2 gene affect substrate and antagonist specificity. Br J Cancer 89, 1971-1978.
-
(2003)
Br J Cancer
, vol.89
, pp. 1971-1978
-
-
Robey, R.W.1
Honjo, Y.2
Morisaki, K.3
Nadjem, T.A.4
Runge, S.5
Risbood, M.6
Poruchynsky, M.S.7
Bates, S.E.8
-
19
-
-
0035815988
-
A functional assay for detection of the mitoxantrone resistance protein, MXR (ABCG2)
-
Robey RW, Honjo Y, van de Laar A, Miyake K, Regis JT, Litman T, and Bates SE (2001). A functional assay for detection of the mitoxantrone resistance protein, MXR (ABCG2). Biochim Biophys Acta 1512, 171-182.
-
(2001)
Biochim Biophys Acta
, vol.1512
, pp. 171-182
-
-
Robey, R.W.1
Honjo, Y.2
van de Laar, A.3
Miyake, K.4
Regis, J.T.5
Litman, T.6
Bates, S.E.7
-
20
-
-
0027432409
-
Fluorescent cellular indicators are extruded by the multidrug resistance protein
-
Homolya L, Hollo Z, Germann UA, Pastan I, Gottesman MM, and Sarkadi B (1993). Fluorescent cellular indicators are extruded by the multidrug resistance protein. J Biol Chem 268, 21493-21496.
-
(1993)
J Biol Chem
, vol.268
, pp. 21493-21496
-
-
Homolya, L.1
Hollo, Z.2
Germann, U.A.3
Pastan, I.4
Gottesman, M.M.5
Sarkadi, B.6
-
21
-
-
0029958849
-
Transport properties of the multidrug resistance-associated protein (MRP) in human tumour cells
-
Hollo Z, Homolya L, Hegedus T, and Sarkadi B (1996). Transport properties of the multidrug resistance-associated protein (MRP) in human tumour cells. FEBS Lett 383, 99-104.
-
(1996)
FEBS Lett
, vol.383
, pp. 99-104
-
-
Hollo, Z.1
Homolya, L.2
Hegedus, T.3
Sarkadi, B.4
-
22
-
-
84965822602
-
Feasibility of drug screening with panels of human tumor cell lines using a microculture tetrazolium assay
-
Alley MC, Scudiero DA, Monks A, Hursey ML, Czerwinski MJ, Fine DL, Abbott BJ, Mayo JG, Shoemaker RH, and Boyd MR (1988). Feasibility of drug screening with panels of human tumor cell lines using a microculture tetrazolium assay. Cancer Res 48, 589-601.
-
(1988)
Cancer Res
, vol.48
, pp. 589-601
-
-
Alley, M.C.1
Scudiero, D.A.2
Monks, A.3
Hursey, M.L.4
Czerwinski, M.J.5
Fine, D.L.6
Abbott, B.J.7
Mayo, J.G.8
Shoemaker, R.H.9
Boyd, M.R.10
-
23
-
-
0023792919
-
Evaluation of a soluble tetrazolium/formazan assay for cell growth and drug sensitivity in culture using human and other tumor cell lines
-
Scudiero DA, Shoemaker RH, Paull KD, Monks A, Tierney S, Nofziger TH, Currens MJ, Seniff D, and Boyd MR (1988). Evaluation of a soluble tetrazolium/formazan assay for cell growth and drug sensitivity in culture using human and other tumor cell lines. Cancer Res 48, 4827-4833.
-
(1988)
Cancer Res
, vol.48
, pp. 4827-4833
-
-
Scudiero, D.A.1
Shoemaker, R.H.2
Paull, K.D.3
Monks, A.4
Tierney, S.5
Nofziger, T.H.6
Currens, M.J.7
Seniff, D.8
Boyd, M.R.9
-
24
-
-
0033966957
-
Fumitremorgin C reverses multidrug resistance in cells transfected with the breast cancer resistance protein
-
Rabindran SK, Ross DD, Doyle LA, Yang W, and Greenberger LM (2000). Fumitremorgin C reverses multidrug resistance in cells transfected with the breast cancer resistance protein. Cancer Res 60, 47-50.
-
(2000)
Cancer Res
, vol.60
, pp. 47-50
-
-
Rabindran, S.K.1
Ross, D.D.2
Doyle, L.A.3
Yang, W.4
Greenberger, L.M.5
-
25
-
-
12344300543
-
Spying on cancer: Molecular imaging in vivo with genetically encoded reporters
-
Gross S and Piwnica-Worms D (2005). Spying on cancer: molecular imaging in vivo with genetically encoded reporters. Cancer Cell 7, 5-15.
-
(2005)
Cancer Cell
, vol.7
, pp. 5-15
-
-
Gross, S.1
Piwnica-Worms, D.2
-
26
-
-
13044249156
-
A multidrug resistance transporter from human MCF-7 breast cancer cells
-
Doyle LA, Yang W, Abruzzo LV, Krogmann T, Gao Y, Rishi AK, and Ross DD (1998). A multidrug resistance transporter from human MCF-7 breast cancer cells. Proc Natl Acad Sci USA 95, 15665-15670.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 15665-15670
-
-
Doyle, L.A.1
Yang, W.2
Abruzzo, L.V.3
Krogmann, T.4
Gao, Y.5
Rishi, A.K.6
Ross, D.D.7
-
27
-
-
0032900953
-
Biochemical, cellular, and pharmacological aspects of the multidrug transporter
-
Ambudkar SV, Dey S, Hrycyna CA, Ramachandra M, Pastan I, and Gottesman MM (1999). Biochemical, cellular, and pharmacological aspects of the multidrug transporter. Annu Rev Pharmacol Toxicol 39, 361-398.
-
(1999)
Annu Rev Pharmacol Toxicol
, vol.39
, pp. 361-398
-
-
Ambudkar, S.V.1
Dey, S.2
Hrycyna, C.A.3
Ramachandra, M.4
Pastan, I.5
Gottesman, M.M.6
-
28
-
-
0023030685
-
Multiple drug-resistant human KB carcinoma cells independently selected for high-level resistance to colchicine, adriamycin, or vinblastine show changes in expression of specific proteins
-
Shen DW, Cardarelli C, Hwang J, Cornwell M, Richert N, Ishii S, Pastan I, and Gottesman MM (1986). Multiple drug-resistant human KB carcinoma cells independently selected for high-level resistance to colchicine, adriamycin, or vinblastine show changes in expression of specific proteins. J Biol Chem 261, 7762-7770.
-
(1986)
J Biol Chem
, vol.261
, pp. 7762-7770
-
-
Shen, D.W.1
Cardarelli, C.2
Hwang, J.3
Cornwell, M.4
Richert, N.5
Ishii, S.6
Pastan, I.7
Gottesman, M.M.8
-
29
-
-
2442675466
-
MRP1 and glucosylceramide are coordinately over expressed and enriched in rafts during multidrug resistance acquisition in colon cancer cells
-
Klappe K, Hinrichs JW, Kroesen BJ, Sietsma H, and Kok JW (2004). MRP1 and glucosylceramide are coordinately over expressed and enriched in rafts during multidrug resistance acquisition in colon cancer cells. Int J Cancer 110, 511-522.
-
(2004)
Int J Cancer
, vol.110
, pp. 511-522
-
-
Klappe, K.1
Hinrichs, J.W.2
Kroesen, B.J.3
Sietsma, H.4
Kok, J.W.5
-
30
-
-
0034081847
-
The multidrug-resistant phenotype associated with overexpression of the new ABC half-transporter, MXR (ABCG2)
-
Litman T, Brangi M, Hudson E, Fetsch P, Abati A, Ross DD, Miyake K, Resau JH, and Bates SE (2000). The multidrug-resistant phenotype associated with overexpression of the new ABC half-transporter, MXR (ABCG2). J Cell Sci 113 (Pt 11), 2011-2021.
-
(2000)
J Cell Sci
, vol.113
, Issue.PART 11
, pp. 2011-2021
-
-
Litman, T.1
Brangi, M.2
Hudson, E.3
Fetsch, P.4
Abati, A.5
Ross, D.D.6
Miyake, K.7
Resau, J.H.8
Bates, S.E.9
-
31
-
-
0034817098
-
Breast cancer resistance protein directly confers SN-38 resistance of lung cancer cells
-
Kawabata S, Oka M, Shiozawa K, Tsukamoto K, Nakatomi K, Soda H, Fukuda M, Ikegami Y, Sugahara K, Yamada Y, et al. (2001). Breast cancer resistance protein directly confers SN-38 resistance of lung cancer cells. Biochem Biophys Res Commun 280, 1216-1223.
-
(2001)
Biochem Biophys Res Commun
, vol.280
, pp. 1216-1223
-
-
Kawabata, S.1
Oka, M.2
Shiozawa, K.3
Tsukamoto, K.4
Nakatomi, K.5
Soda, H.6
Fukuda, M.7
Ikegami, Y.8
Sugahara, K.9
Yamada, Y.10
-
32
-
-
0033429542
-
Camptothecin resistance: Role of the ATP-binding cassette (ABC), mitoxantrone-resistance half-transporter (MXR), and potential for glucuronidation in MXR-expressing cells
-
Brangi M, Litman T, Ciotti M, Nishiyama K, Kohlhagen G, Takimoto C, Robey R, Pommier Y, Fojo T, and Bates SE (1999). Camptothecin resistance: role of the ATP-binding cassette (ABC), mitoxantrone-resistance half-transporter (MXR), and potential for glucuronidation in MXR-expressing cells. Cancer Res 59, 5938-5946.
-
(1999)
Cancer Res
, vol.59
, pp. 5938-5946
-
-
Brangi, M.1
Litman, T.2
Ciotti, M.3
Nishiyama, K.4
Kohlhagen, G.5
Takimoto, C.6
Robey, R.7
Pommier, Y.8
Fojo, T.9
Bates, S.E.10
-
33
-
-
1642454475
-
ABC transporters and the blood-brain barrier
-
Begley DJ (2004). ABC transporters and the blood-brain barrier. Curr Pharm Des 10, 1295-1312.
-
(2004)
Curr Pharm Des
, vol.10
, pp. 1295-1312
-
-
Begley, D.J.1
-
34
-
-
0033763084
-
ZD1839 ("Iressa") as an anticancer agent
-
discussion 41-42
-
Baselga J and Averbuch SD (2000). ZD1839 ("Iressa") as an anticancer agent. Drugs 60 (Suppl 1), 33-40, discussion 41-42.
-
(2000)
Drugs
, vol.60
, Issue.SUPPL. 1
, pp. 33-40
-
-
Baselga, J.1
Averbuch, S.D.2
-
35
-
-
13944269488
-
Gefitinib ("Iressa", ZD1839), an epidermal growth factor receptor tyrosine kinase inhibitor, reverses breast cancer resistance protein/ABCG2-mediated drug resistance
-
Nakamura Y, Oka M, Soda H, Shiozawa K, Yoshikawa M, Itoh A, Ikegami Y, Tsurutani J, Nakatomi K, Kitazaki T, et al. (2005). Gefitinib ("Iressa", ZD1839), an epidermal growth factor receptor tyrosine kinase inhibitor, reverses breast cancer resistance protein/ABCG2-mediated drug resistance. Cancer Res 65, 1541-1546.
-
(2005)
Cancer Res
, vol.65
, pp. 1541-1546
-
-
Nakamura, Y.1
Oka, M.2
Soda, H.3
Shiozawa, K.4
Yoshikawa, M.5
Itoh, A.6
Ikegami, Y.7
Tsurutani, J.8
Nakatomi, K.9
Kitazaki, T.10
-
36
-
-
20144389530
-
Multidrug transporter ABCG2 prevents tumor cell death induced by the epidermal growth factor receptor inhibitor Iressa (ZD1839, gefitinib)
-
Elkind NB, Szentpetery Z, Apati A, Ozvegy-Laczka C, Varady G, Ujhelly O, Szabo K, Homolya L, Varadi A, Buday L, et al. (2005). Multidrug transporter ABCG2 prevents tumor cell death induced by the epidermal growth factor receptor inhibitor Iressa (ZD1839, gefitinib). Cancer Res 65, 1770-1777.
-
(2005)
Cancer Res
, vol.65
, pp. 1770-1777
-
-
Elkind, N.B.1
Szentpetery, Z.2
Apati, A.3
Ozvegy-Laczka, C.4
Varady, G.5
Ujhelly, O.6
Szabo, K.7
Homolya, L.8
Varadi, A.9
Buday, L.10
-
37
-
-
1942506722
-
Imatinib mesylate is a potent inhibitor of the ABCG2 (BCRP) transporter and reverses resistance to topotecan and SN-38 in vitro
-
Houghton PJ, Germain GS, Harwood FC, Schuetz JD, Stewart CF, Buchdunger E, and Traxler P (2004). Imatinib mesylate is a potent inhibitor of the ABCG2 (BCRP) transporter and reverses resistance to topotecan and SN-38 in vitro. Cancer Res 64, 2333-2337.
-
(2004)
Cancer Res
, vol.64
, pp. 2333-2337
-
-
Houghton, P.J.1
Germain, G.S.2
Harwood, F.C.3
Schuetz, J.D.4
Stewart, C.F.5
Buchdunger, E.6
Traxler, P.7
-
38
-
-
36348967305
-
Erlotinib (Tarceva, OSI-774) antagonizes ATP-binding cassette subfamily B member 1 and ATP-binding cassette subfamily G member 2-mediated drug resistance
-
Shi Z, Peng XX, Kim IW, Shukla S, Si QS, Robey RW, Bates SE, Shen T, Ashby CR Jr, Fu LW, et al. (2007). Erlotinib (Tarceva, OSI-774) antagonizes ATP-binding cassette subfamily B member 1 and ATP-binding cassette subfamily G member 2-mediated drug resistance. Cancer Res 67, 11012-11020.
-
(2007)
Cancer Res
, vol.67
, pp. 11012-11020
-
-
Shi, Z.1
Peng, X.X.2
Kim, I.W.3
Shukla, S.4
Si, Q.S.5
Robey, R.W.6
Bates, S.E.7
Shen, T.8
Ashby Jr, C.R.9
Fu, L.W.10
-
39
-
-
2442638937
-
High-affinity interaction of tyrosine kinase inhibitors with the ABCG2 multidrug transporter
-
Ozvegy-Laczka C, Hegedus T, Varady G, Ujhelly O, Schuetz JD, Varadi A, Keri G, Orfi L, Nemet K, and Sarkadi B (2004). High-affinity interaction of tyrosine kinase inhibitors with the ABCG2 multidrug transporter. Mol Pharmacol 65, 1485-1495.
-
(2004)
Mol Pharmacol
, vol.65
, pp. 1485-1495
-
-
Ozvegy-Laczka, C.1
Hegedus, T.2
Varady, G.3
Ujhelly, O.4
Schuetz, J.D.5
Varadi, A.6
Keri, G.7
Orfi, L.8
Nemet, K.9
Sarkadi, B.10
-
40
-
-
0344520475
-
Distribution of STI-571 to the brain is limited by P-glycoprotein-mediated efflux
-
Dai H, Marbach P, Lemaire M, Hayes M, and Elmquist WF (2003). Distribution of STI-571 to the brain is limited by P-glycoprotein-mediated efflux. J Pharmacol Exp Ther 304, 1085-1092.
-
(2003)
J Pharmacol Exp Ther
, vol.304
, pp. 1085-1092
-
-
Dai, H.1
Marbach, P.2
Lemaire, M.3
Hayes, M.4
Elmquist, W.F.5
-
41
-
-
33947498515
-
Modulation of human BCRP (ABCG2) activity by anti-HIV drugs
-
Weiss J, Rose J, Storch CH, Ketabi-Kiyanvash N, Sauer A, Haefeli WE, and Efferth T (2007). Modulation of human BCRP (ABCG2) activity by anti-HIV drugs. J Antimicrob Chemother 59, 238-245.
-
(2007)
J Antimicrob Chemother
, vol.59
, pp. 238-245
-
-
Weiss, J.1
Rose, J.2
Storch, C.H.3
Ketabi-Kiyanvash, N.4
Sauer, A.5
Haefeli, W.E.6
Efferth, T.7
-
42
-
-
33645499870
-
EGFR regulates the side population in head and neck squamous cell carcinoma
-
Chen JS, Pardo FS, Wang-Rodriguez J, Chu TS, Lopez JP, Aguilera J, Altuna X, Weisman RA, and Ongkeko WM (2006). EGFR regulates the side population in head and neck squamous cell carcinoma. Laryngoscope 116, 401-406.
-
(2006)
Laryngoscope
, vol.116
, pp. 401-406
-
-
Chen, J.S.1
Pardo, F.S.2
Wang-Rodriguez, J.3
Chu, T.S.4
Lopez, J.P.5
Aguilera, J.6
Altuna, X.7
Weisman, R.A.8
Ongkeko, W.M.9
-
43
-
-
22344435180
-
Regulation of the cell surface expression of human BCRP/ABCG2 by the phosphorylation state of Akt in polarized cells
-
Takada T, Suzuki H, Gotoh Y, and Sugiyama Y (2005). Regulation of the cell surface expression of human BCRP/ABCG2 by the phosphorylation state of Akt in polarized cells. Drug Metab Dispos 33, 905-909.
-
(2005)
Drug Metab Dispos
, vol.33
, pp. 905-909
-
-
Takada, T.1
Suzuki, H.2
Gotoh, Y.3
Sugiyama, Y.4
-
44
-
-
33645097928
-
Epidermal growth factor-mediated activation of the map kinase cascade results in altered expression and function of ABCG2 (BCRP)
-
Meyer zu Schwabedissen HE, Grube M, Dreisbach A, Jedlitschky G, Meissner K, Linnemann K, Fusch C, Ritter CA, Volker U, and Kroemer HK (2006). Epidermal growth factor-mediated activation of the map kinase cascade results in altered expression and function of ABCG2 (BCRP). Drug Metab Dispos 34, 524-533.
-
(2006)
Drug Metab Dispos
, vol.34
, pp. 524-533
-
-
Meyer zu Schwabedissen, H.E.1
Grube, M.2
Dreisbach, A.3
Jedlitschky, G.4
Meissner, K.5
Linnemann, K.6
Fusch, C.7
Ritter, C.A.8
Volker, U.9
Kroemer, H.K.10
-
45
-
-
33745953739
-
Complex interaction of BCRP/ABCG2 and imatinib in BCR-ABL-expressing cells: BCRP-mediated resistance to imatinib is attenuated by imatinib-induced reduction of BCRP expression
-
Nakanishi T, Shiozawa K, Hassel BA, and Ross DD (2006). Complex interaction of BCRP/ABCG2 and imatinib in BCR-ABL-expressing cells: BCRP-mediated resistance to imatinib is attenuated by imatinib-induced reduction of BCRP expression. Blood 108, 678-684.
-
(2006)
Blood
, vol.108
, pp. 678-684
-
-
Nakanishi, T.1
Shiozawa, K.2
Hassel, B.A.3
Ross, D.D.4
-
46
-
-
41249100545
-
The 44-kDa Pim-1 kinase phosphorylates BCRP/ABCG2 and thereby promotes its multimerization and drug-resistant activity in human prostate cancer cells
-
Xie Y, Xu K, Linn DE, Yang X, Guo Z, Shimelis H, Nakanishi T, Ross DD, Chen H, Fazli L, et al. (2008). The 44-kDa Pim-1 kinase phosphorylates BCRP/ABCG2 and thereby promotes its multimerization and drug-resistant activity in human prostate cancer cells. J Biol Chem 283, 3349-3356.
-
(2008)
J Biol Chem
, vol.283
, pp. 3349-3356
-
-
Xie, Y.1
Xu, K.2
Linn, D.E.3
Yang, X.4
Guo, Z.5
Shimelis, H.6
Nakanishi, T.7
Ross, D.D.8
Chen, H.9
Fazli, L.10
-
47
-
-
16844368698
-
Tumour stem cells and drug resistance
-
Dean M, Fojo T, and Bates S (2005). Tumour stem cells and drug resistance. Nat Rev Cancer 5, 275-284.
-
(2005)
Nat Rev Cancer
, vol.5
, pp. 275-284
-
-
Dean, M.1
Fojo, T.2
Bates, S.3
|