Sonic hedgehog protein promotes bone marrow-derived endothelial progenitor cell proliferation, migration and VEGF production via PI 3-kinase/Akt signaling pathways

Acta Pharmacologica Sinica

Volumn 27, Issue 6, 2006, Pages 685-693

  Fu, Jin Rong ^a   Liu, Wen Li ^a   Zhou, Jian Feng ^a   Sun, Han Ying ^a   Xu, Hui Zhen ^a   Luo, Li ^a   Zhang, Heng ^a   Zhou, Yu Feng ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

1 phos phatidylinositol 3 kinase; Cell proliferation; Emigration; Endothelial cells; Immigration; Mouse Sonic hedgehog protein; Protein kinase C; Stem cells; Vascular endothelial growth factor A

Indexed keywords

1 (5 ISOQUINOLINESULFONYL) 2 METHYLPIPERAZINE; 2 MORPHOLINO 8 PHENYLCHROMONE; BETA ACTIN; PEPTIDE ANTIBODY; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; PROTEIN KINASE B; SONIC HEDGEHOG PROTEIN; VASCULOTROPIN;

ANGIOGENESIS; ANIMAL CELL; ARTICLE; BONE MARROW CELL; CELL MIGRATION; CELL PROLIFERATION; CONTROLLED STUDY; ENDOTHELIUM CELL; ENZYME ACTIVATION; ENZYME LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; ISCHEMIA; MOUSE; NEOVASCULARIZATION (PATHOLOGY); NONHUMAN; PROTEIN ANALYSIS; SIGNAL TRANSDUCTION; STEM CELL; WESTERN BLOTTING;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; BONE MARROW CELLS; CELL MOVEMENT; CELL PROLIFERATION; CELLS, CULTURED; ENDOTHELIAL CELLS; HEDGEHOG PROTEINS; MICE; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION; STEM CELLS; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 33745379407     PISSN: 16714083     EISSN: 17457254     Source Type: Journal    
DOI: 10.1111/j.1745-7254.2006.00335.x     Document Type: Article

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