Cyclopamine-mediated Hedgehog pathway inhibition depletes stem-like cancer cells in glioblastoma

Stem Cells

Volumn 25, Issue 10, 2007, Pages 2524-2533

  Bar, Eli E ^a   Chaudhry, Aneeka ^a   Lin, Alex ^a   Fan, Xing ^a   Schreck, Karisa ^a   Matsui, William ^a   Piccirillo, Sara ^b   Vescovi, Angelo L ^b   DiMeco, Francesco ^c   Olivi, Alessandro ^a   Eberhart, Charles G ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF MILANO BICOCCA   (Italy)

^c DEPARTMENT OF NEUROSURGERY   (Italy)

Author keywords

Glioma; Hedgehog; Stem cell

Indexed keywords

CYCLOPAMINE; HOE 33342; TRANSCRIPTION FACTOR GLI1;

ANIMAL CELL; ARTICLE; CANCER CELL; CELL DIFFERENTIATION; CONTROLLED STUDY; GLIOBLASTOMA; GLIOMA; HEDGEHOG; NONHUMAN; PROTEIN EXPRESSION; STEM CELL; TUMOR CELL;

ANIMALS; CELL LINE, TUMOR; ETHANOL; GAMMA RAYS; GLIOBLASTOMA; HEDGEHOG PROTEINS; HUMANS; MICE; MICE, NUDE; NEOPLASM PROTEINS; NEOPLASM TRANSPLANTATION; NEOPLASTIC STEM CELLS; RNA, MESSENGER; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS; VERATRUM ALKALOIDS;

ERINACEIDAE; MUS;

EID: 35348837163     PISSN: 10665099     EISSN: None     Source Type: Journal    
DOI: 10.1634/stemcells.2007-0166     Document Type: Article

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